Annotation of imach/src/imach.c, revision 1.313

1.313   ! brouard     1: /* $Id: imach.c,v 1.312 2022/04/05 21:24:39 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.313   ! brouard     4:   Revision 1.312  2022/04/05 21:24:39  brouard
        !             5:   *** empty log message ***
        !             6: 
1.312     brouard     7:   Revision 1.311  2022/04/05 21:03:51  brouard
                      8:   Summary: Fixed quantitative covariates
                      9: 
                     10:          Fixed covariates (dummy or quantitative)
                     11:        with missing values have never been allowed but are ERRORS and
                     12:        program quits. Standard deviations of fixed covariates were
                     13:        wrongly computed. Mean and standard deviations of time varying
                     14:        covariates are still not computed.
                     15: 
1.311     brouard    16:   Revision 1.310  2022/03/17 08:45:53  brouard
                     17:   Summary: 99r25
                     18: 
                     19:   Improving detection of errors: result lines should be compatible with
                     20:   the model.
                     21: 
1.310     brouard    22:   Revision 1.309  2021/05/20 12:39:14  brouard
                     23:   Summary: Version 0.99r24
                     24: 
1.309     brouard    25:   Revision 1.308  2021/03/31 13:11:57  brouard
                     26:   Summary: Version 0.99r23
                     27: 
                     28: 
                     29:   * imach.c (Module): Still bugs in the result loop. Thank to Holly Benett
                     30: 
1.308     brouard    31:   Revision 1.307  2021/03/08 18:11:32  brouard
                     32:   Summary: 0.99r22 fixed bug on result:
                     33: 
1.307     brouard    34:   Revision 1.306  2021/02/20 15:44:02  brouard
                     35:   Summary: Version 0.99r21
                     36: 
                     37:   * imach.c (Module): Fix bug on quitting after result lines!
                     38:   (Module): Version 0.99r21
                     39: 
1.306     brouard    40:   Revision 1.305  2021/02/20 15:28:30  brouard
                     41:   * imach.c (Module): Fix bug on quitting after result lines!
                     42: 
1.305     brouard    43:   Revision 1.304  2021/02/12 11:34:20  brouard
                     44:   * imach.c (Module): The use of a Windows BOM (huge) file is now an error
                     45: 
1.304     brouard    46:   Revision 1.303  2021/02/11 19:50:15  brouard
                     47:   *  (Module): imach.c Someone entered 'results:' instead of 'result:'. Now it is an error which is printed.
                     48: 
1.303     brouard    49:   Revision 1.302  2020/02/22 21:00:05  brouard
                     50:   *  (Module): imach.c Update mle=-3 (for computing Life expectancy
                     51:   and life table from the data without any state)
                     52: 
1.302     brouard    53:   Revision 1.301  2019/06/04 13:51:20  brouard
                     54:   Summary: Error in 'r'parameter file backcast yearsbproj instead of yearsfproj
                     55: 
1.301     brouard    56:   Revision 1.300  2019/05/22 19:09:45  brouard
                     57:   Summary: version 0.99r19 of May 2019
                     58: 
1.300     brouard    59:   Revision 1.299  2019/05/22 18:37:08  brouard
                     60:   Summary: Cleaned 0.99r19
                     61: 
1.299     brouard    62:   Revision 1.298  2019/05/22 18:19:56  brouard
                     63:   *** empty log message ***
                     64: 
1.298     brouard    65:   Revision 1.297  2019/05/22 17:56:10  brouard
                     66:   Summary: Fix bug by moving date2dmy and nhstepm which gaefin=-1
                     67: 
1.297     brouard    68:   Revision 1.296  2019/05/20 13:03:18  brouard
                     69:   Summary: Projection syntax simplified
                     70: 
                     71: 
                     72:   We can now start projections, forward or backward, from the mean date
                     73:   of inteviews up to or down to a number of years of projection:
                     74:   prevforecast=1 yearsfproj=15.3 mobil_average=0
                     75:   or
                     76:   prevforecast=1 starting-proj-date=1/1/2007 final-proj-date=12/31/2017 mobil_average=0
                     77:   or
                     78:   prevbackcast=1 yearsbproj=12.3 mobil_average=1
                     79:   or
                     80:   prevbackcast=1 starting-back-date=1/10/1999 final-back-date=1/1/1985 mobil_average=1
                     81: 
1.296     brouard    82:   Revision 1.295  2019/05/18 09:52:50  brouard
                     83:   Summary: doxygen tex bug
                     84: 
1.295     brouard    85:   Revision 1.294  2019/05/16 14:54:33  brouard
                     86:   Summary: There was some wrong lines added
                     87: 
1.294     brouard    88:   Revision 1.293  2019/05/09 15:17:34  brouard
                     89:   *** empty log message ***
                     90: 
1.293     brouard    91:   Revision 1.292  2019/05/09 14:17:20  brouard
                     92:   Summary: Some updates
                     93: 
1.292     brouard    94:   Revision 1.291  2019/05/09 13:44:18  brouard
                     95:   Summary: Before ncovmax
                     96: 
1.291     brouard    97:   Revision 1.290  2019/05/09 13:39:37  brouard
                     98:   Summary: 0.99r18 unlimited number of individuals
                     99: 
                    100:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
                    101: 
1.290     brouard   102:   Revision 1.289  2018/12/13 09:16:26  brouard
                    103:   Summary: Bug for young ages (<-30) will be in r17
                    104: 
1.289     brouard   105:   Revision 1.288  2018/05/02 20:58:27  brouard
                    106:   Summary: Some bugs fixed
                    107: 
1.288     brouard   108:   Revision 1.287  2018/05/01 17:57:25  brouard
                    109:   Summary: Bug fixed by providing frequencies only for non missing covariates
                    110: 
1.287     brouard   111:   Revision 1.286  2018/04/27 14:27:04  brouard
                    112:   Summary: some minor bugs
                    113: 
1.286     brouard   114:   Revision 1.285  2018/04/21 21:02:16  brouard
                    115:   Summary: Some bugs fixed, valgrind tested
                    116: 
1.285     brouard   117:   Revision 1.284  2018/04/20 05:22:13  brouard
                    118:   Summary: Computing mean and stdeviation of fixed quantitative variables
                    119: 
1.284     brouard   120:   Revision 1.283  2018/04/19 14:49:16  brouard
                    121:   Summary: Some minor bugs fixed
                    122: 
1.283     brouard   123:   Revision 1.282  2018/02/27 22:50:02  brouard
                    124:   *** empty log message ***
                    125: 
1.282     brouard   126:   Revision 1.281  2018/02/27 19:25:23  brouard
                    127:   Summary: Adding second argument for quitting
                    128: 
1.281     brouard   129:   Revision 1.280  2018/02/21 07:58:13  brouard
                    130:   Summary: 0.99r15
                    131: 
                    132:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                    133: 
1.280     brouard   134:   Revision 1.279  2017/07/20 13:35:01  brouard
                    135:   Summary: temporary working
                    136: 
1.279     brouard   137:   Revision 1.278  2017/07/19 14:09:02  brouard
                    138:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                    139: 
1.278     brouard   140:   Revision 1.277  2017/07/17 08:53:49  brouard
                    141:   Summary: BOM files can be read now
                    142: 
1.277     brouard   143:   Revision 1.276  2017/06/30 15:48:31  brouard
                    144:   Summary: Graphs improvements
                    145: 
1.276     brouard   146:   Revision 1.275  2017/06/30 13:39:33  brouard
                    147:   Summary: Saito's color
                    148: 
1.275     brouard   149:   Revision 1.274  2017/06/29 09:47:08  brouard
                    150:   Summary: Version 0.99r14
                    151: 
1.274     brouard   152:   Revision 1.273  2017/06/27 11:06:02  brouard
                    153:   Summary: More documentation on projections
                    154: 
1.273     brouard   155:   Revision 1.272  2017/06/27 10:22:40  brouard
                    156:   Summary: Color of backprojection changed from 6 to 5(yellow)
                    157: 
1.272     brouard   158:   Revision 1.271  2017/06/27 10:17:50  brouard
                    159:   Summary: Some bug with rint
                    160: 
1.271     brouard   161:   Revision 1.270  2017/05/24 05:45:29  brouard
                    162:   *** empty log message ***
                    163: 
1.270     brouard   164:   Revision 1.269  2017/05/23 08:39:25  brouard
                    165:   Summary: Code into subroutine, cleanings
                    166: 
1.269     brouard   167:   Revision 1.268  2017/05/18 20:09:32  brouard
                    168:   Summary: backprojection and confidence intervals of backprevalence
                    169: 
1.268     brouard   170:   Revision 1.267  2017/05/13 10:25:05  brouard
                    171:   Summary: temporary save for backprojection
                    172: 
1.267     brouard   173:   Revision 1.266  2017/05/13 07:26:12  brouard
                    174:   Summary: Version 0.99r13 (improvements and bugs fixed)
                    175: 
1.266     brouard   176:   Revision 1.265  2017/04/26 16:22:11  brouard
                    177:   Summary: imach 0.99r13 Some bugs fixed
                    178: 
1.265     brouard   179:   Revision 1.264  2017/04/26 06:01:29  brouard
                    180:   Summary: Labels in graphs
                    181: 
1.264     brouard   182:   Revision 1.263  2017/04/24 15:23:15  brouard
                    183:   Summary: to save
                    184: 
1.263     brouard   185:   Revision 1.262  2017/04/18 16:48:12  brouard
                    186:   *** empty log message ***
                    187: 
1.262     brouard   188:   Revision 1.261  2017/04/05 10:14:09  brouard
                    189:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                    190: 
1.261     brouard   191:   Revision 1.260  2017/04/04 17:46:59  brouard
                    192:   Summary: Gnuplot indexations fixed (humm)
                    193: 
1.260     brouard   194:   Revision 1.259  2017/04/04 13:01:16  brouard
                    195:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    196: 
1.259     brouard   197:   Revision 1.258  2017/04/03 10:17:47  brouard
                    198:   Summary: Version 0.99r12
                    199: 
                    200:   Some cleanings, conformed with updated documentation.
                    201: 
1.258     brouard   202:   Revision 1.257  2017/03/29 16:53:30  brouard
                    203:   Summary: Temp
                    204: 
1.257     brouard   205:   Revision 1.256  2017/03/27 05:50:23  brouard
                    206:   Summary: Temporary
                    207: 
1.256     brouard   208:   Revision 1.255  2017/03/08 16:02:28  brouard
                    209:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    210: 
1.255     brouard   211:   Revision 1.254  2017/03/08 07:13:00  brouard
                    212:   Summary: Fixing data parameter line
                    213: 
1.254     brouard   214:   Revision 1.253  2016/12/15 11:59:41  brouard
                    215:   Summary: 0.99 in progress
                    216: 
1.253     brouard   217:   Revision 1.252  2016/09/15 21:15:37  brouard
                    218:   *** empty log message ***
                    219: 
1.252     brouard   220:   Revision 1.251  2016/09/15 15:01:13  brouard
                    221:   Summary: not working
                    222: 
1.251     brouard   223:   Revision 1.250  2016/09/08 16:07:27  brouard
                    224:   Summary: continue
                    225: 
1.250     brouard   226:   Revision 1.249  2016/09/07 17:14:18  brouard
                    227:   Summary: Starting values from frequencies
                    228: 
1.249     brouard   229:   Revision 1.248  2016/09/07 14:10:18  brouard
                    230:   *** empty log message ***
                    231: 
1.248     brouard   232:   Revision 1.247  2016/09/02 11:11:21  brouard
                    233:   *** empty log message ***
                    234: 
1.247     brouard   235:   Revision 1.246  2016/09/02 08:49:22  brouard
                    236:   *** empty log message ***
                    237: 
1.246     brouard   238:   Revision 1.245  2016/09/02 07:25:01  brouard
                    239:   *** empty log message ***
                    240: 
1.245     brouard   241:   Revision 1.244  2016/09/02 07:17:34  brouard
                    242:   *** empty log message ***
                    243: 
1.244     brouard   244:   Revision 1.243  2016/09/02 06:45:35  brouard
                    245:   *** empty log message ***
                    246: 
1.243     brouard   247:   Revision 1.242  2016/08/30 15:01:20  brouard
                    248:   Summary: Fixing a lots
                    249: 
1.242     brouard   250:   Revision 1.241  2016/08/29 17:17:25  brouard
                    251:   Summary: gnuplot problem in Back projection to fix
                    252: 
1.241     brouard   253:   Revision 1.240  2016/08/29 07:53:18  brouard
                    254:   Summary: Better
                    255: 
1.240     brouard   256:   Revision 1.239  2016/08/26 15:51:03  brouard
                    257:   Summary: Improvement in Powell output in order to copy and paste
                    258: 
                    259:   Author:
                    260: 
1.239     brouard   261:   Revision 1.238  2016/08/26 14:23:35  brouard
                    262:   Summary: Starting tests of 0.99
                    263: 
1.238     brouard   264:   Revision 1.237  2016/08/26 09:20:19  brouard
                    265:   Summary: to valgrind
                    266: 
1.237     brouard   267:   Revision 1.236  2016/08/25 10:50:18  brouard
                    268:   *** empty log message ***
                    269: 
1.236     brouard   270:   Revision 1.235  2016/08/25 06:59:23  brouard
                    271:   *** empty log message ***
                    272: 
1.235     brouard   273:   Revision 1.234  2016/08/23 16:51:20  brouard
                    274:   *** empty log message ***
                    275: 
1.234     brouard   276:   Revision 1.233  2016/08/23 07:40:50  brouard
                    277:   Summary: not working
                    278: 
1.233     brouard   279:   Revision 1.232  2016/08/22 14:20:21  brouard
                    280:   Summary: not working
                    281: 
1.232     brouard   282:   Revision 1.231  2016/08/22 07:17:15  brouard
                    283:   Summary: not working
                    284: 
1.231     brouard   285:   Revision 1.230  2016/08/22 06:55:53  brouard
                    286:   Summary: Not working
                    287: 
1.230     brouard   288:   Revision 1.229  2016/07/23 09:45:53  brouard
                    289:   Summary: Completing for func too
                    290: 
1.229     brouard   291:   Revision 1.228  2016/07/22 17:45:30  brouard
                    292:   Summary: Fixing some arrays, still debugging
                    293: 
1.227     brouard   294:   Revision 1.226  2016/07/12 18:42:34  brouard
                    295:   Summary: temp
                    296: 
1.226     brouard   297:   Revision 1.225  2016/07/12 08:40:03  brouard
                    298:   Summary: saving but not running
                    299: 
1.225     brouard   300:   Revision 1.224  2016/07/01 13:16:01  brouard
                    301:   Summary: Fixes
                    302: 
1.224     brouard   303:   Revision 1.223  2016/02/19 09:23:35  brouard
                    304:   Summary: temporary
                    305: 
1.223     brouard   306:   Revision 1.222  2016/02/17 08:14:50  brouard
                    307:   Summary: Probably last 0.98 stable version 0.98r6
                    308: 
1.222     brouard   309:   Revision 1.221  2016/02/15 23:35:36  brouard
                    310:   Summary: minor bug
                    311: 
1.220     brouard   312:   Revision 1.219  2016/02/15 00:48:12  brouard
                    313:   *** empty log message ***
                    314: 
1.219     brouard   315:   Revision 1.218  2016/02/12 11:29:23  brouard
                    316:   Summary: 0.99 Back projections
                    317: 
1.218     brouard   318:   Revision 1.217  2015/12/23 17:18:31  brouard
                    319:   Summary: Experimental backcast
                    320: 
1.217     brouard   321:   Revision 1.216  2015/12/18 17:32:11  brouard
                    322:   Summary: 0.98r4 Warning and status=-2
                    323: 
                    324:   Version 0.98r4 is now:
                    325:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    326:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    327:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    328: 
1.216     brouard   329:   Revision 1.215  2015/12/16 08:52:24  brouard
                    330:   Summary: 0.98r4 working
                    331: 
1.215     brouard   332:   Revision 1.214  2015/12/16 06:57:54  brouard
                    333:   Summary: temporary not working
                    334: 
1.214     brouard   335:   Revision 1.213  2015/12/11 18:22:17  brouard
                    336:   Summary: 0.98r4
                    337: 
1.213     brouard   338:   Revision 1.212  2015/11/21 12:47:24  brouard
                    339:   Summary: minor typo
                    340: 
1.212     brouard   341:   Revision 1.211  2015/11/21 12:41:11  brouard
                    342:   Summary: 0.98r3 with some graph of projected cross-sectional
                    343: 
                    344:   Author: Nicolas Brouard
                    345: 
1.211     brouard   346:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   347:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   348:   Summary: Adding ftolpl parameter
                    349:   Author: N Brouard
                    350: 
                    351:   We had difficulties to get smoothed confidence intervals. It was due
                    352:   to the period prevalence which wasn't computed accurately. The inner
                    353:   parameter ftolpl is now an outer parameter of the .imach parameter
                    354:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    355:   computation are long.
                    356: 
1.209     brouard   357:   Revision 1.208  2015/11/17 14:31:57  brouard
                    358:   Summary: temporary
                    359: 
1.208     brouard   360:   Revision 1.207  2015/10/27 17:36:57  brouard
                    361:   *** empty log message ***
                    362: 
1.207     brouard   363:   Revision 1.206  2015/10/24 07:14:11  brouard
                    364:   *** empty log message ***
                    365: 
1.206     brouard   366:   Revision 1.205  2015/10/23 15:50:53  brouard
                    367:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    368: 
1.205     brouard   369:   Revision 1.204  2015/10/01 16:20:26  brouard
                    370:   Summary: Some new graphs of contribution to likelihood
                    371: 
1.204     brouard   372:   Revision 1.203  2015/09/30 17:45:14  brouard
                    373:   Summary: looking at better estimation of the hessian
                    374: 
                    375:   Also a better criteria for convergence to the period prevalence And
                    376:   therefore adding the number of years needed to converge. (The
                    377:   prevalence in any alive state shold sum to one
                    378: 
1.203     brouard   379:   Revision 1.202  2015/09/22 19:45:16  brouard
                    380:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    381: 
1.202     brouard   382:   Revision 1.201  2015/09/15 17:34:58  brouard
                    383:   Summary: 0.98r0
                    384: 
                    385:   - Some new graphs like suvival functions
                    386:   - Some bugs fixed like model=1+age+V2.
                    387: 
1.201     brouard   388:   Revision 1.200  2015/09/09 16:53:55  brouard
                    389:   Summary: Big bug thanks to Flavia
                    390: 
                    391:   Even model=1+age+V2. did not work anymore
                    392: 
1.200     brouard   393:   Revision 1.199  2015/09/07 14:09:23  brouard
                    394:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    395: 
1.199     brouard   396:   Revision 1.198  2015/09/03 07:14:39  brouard
                    397:   Summary: 0.98q5 Flavia
                    398: 
1.198     brouard   399:   Revision 1.197  2015/09/01 18:24:39  brouard
                    400:   *** empty log message ***
                    401: 
1.197     brouard   402:   Revision 1.196  2015/08/18 23:17:52  brouard
                    403:   Summary: 0.98q5
                    404: 
1.196     brouard   405:   Revision 1.195  2015/08/18 16:28:39  brouard
                    406:   Summary: Adding a hack for testing purpose
                    407: 
                    408:   After reading the title, ftol and model lines, if the comment line has
                    409:   a q, starting with #q, the answer at the end of the run is quit. It
                    410:   permits to run test files in batch with ctest. The former workaround was
                    411:   $ echo q | imach foo.imach
                    412: 
1.195     brouard   413:   Revision 1.194  2015/08/18 13:32:00  brouard
                    414:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    415: 
1.194     brouard   416:   Revision 1.193  2015/08/04 07:17:42  brouard
                    417:   Summary: 0.98q4
                    418: 
1.193     brouard   419:   Revision 1.192  2015/07/16 16:49:02  brouard
                    420:   Summary: Fixing some outputs
                    421: 
1.192     brouard   422:   Revision 1.191  2015/07/14 10:00:33  brouard
                    423:   Summary: Some fixes
                    424: 
1.191     brouard   425:   Revision 1.190  2015/05/05 08:51:13  brouard
                    426:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    427: 
                    428:   Fix 1+age+.
                    429: 
1.190     brouard   430:   Revision 1.189  2015/04/30 14:45:16  brouard
                    431:   Summary: 0.98q2
                    432: 
1.189     brouard   433:   Revision 1.188  2015/04/30 08:27:53  brouard
                    434:   *** empty log message ***
                    435: 
1.188     brouard   436:   Revision 1.187  2015/04/29 09:11:15  brouard
                    437:   *** empty log message ***
                    438: 
1.187     brouard   439:   Revision 1.186  2015/04/23 12:01:52  brouard
                    440:   Summary: V1*age is working now, version 0.98q1
                    441: 
                    442:   Some codes had been disabled in order to simplify and Vn*age was
                    443:   working in the optimization phase, ie, giving correct MLE parameters,
                    444:   but, as usual, outputs were not correct and program core dumped.
                    445: 
1.186     brouard   446:   Revision 1.185  2015/03/11 13:26:42  brouard
                    447:   Summary: Inclusion of compile and links command line for Intel Compiler
                    448: 
1.185     brouard   449:   Revision 1.184  2015/03/11 11:52:39  brouard
                    450:   Summary: Back from Windows 8. Intel Compiler
                    451: 
1.184     brouard   452:   Revision 1.183  2015/03/10 20:34:32  brouard
                    453:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    454: 
                    455:   We use directest instead of original Powell test; probably no
                    456:   incidence on the results, but better justifications;
                    457:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    458:   wrong results.
                    459: 
1.183     brouard   460:   Revision 1.182  2015/02/12 08:19:57  brouard
                    461:   Summary: Trying to keep directest which seems simpler and more general
                    462:   Author: Nicolas Brouard
                    463: 
1.182     brouard   464:   Revision 1.181  2015/02/11 23:22:24  brouard
                    465:   Summary: Comments on Powell added
                    466: 
                    467:   Author:
                    468: 
1.181     brouard   469:   Revision 1.180  2015/02/11 17:33:45  brouard
                    470:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    471: 
1.180     brouard   472:   Revision 1.179  2015/01/04 09:57:06  brouard
                    473:   Summary: back to OS/X
                    474: 
1.179     brouard   475:   Revision 1.178  2015/01/04 09:35:48  brouard
                    476:   *** empty log message ***
                    477: 
1.178     brouard   478:   Revision 1.177  2015/01/03 18:40:56  brouard
                    479:   Summary: Still testing ilc32 on OSX
                    480: 
1.177     brouard   481:   Revision 1.176  2015/01/03 16:45:04  brouard
                    482:   *** empty log message ***
                    483: 
1.176     brouard   484:   Revision 1.175  2015/01/03 16:33:42  brouard
                    485:   *** empty log message ***
                    486: 
1.175     brouard   487:   Revision 1.174  2015/01/03 16:15:49  brouard
                    488:   Summary: Still in cross-compilation
                    489: 
1.174     brouard   490:   Revision 1.173  2015/01/03 12:06:26  brouard
                    491:   Summary: trying to detect cross-compilation
                    492: 
1.173     brouard   493:   Revision 1.172  2014/12/27 12:07:47  brouard
                    494:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    495: 
1.172     brouard   496:   Revision 1.171  2014/12/23 13:26:59  brouard
                    497:   Summary: Back from Visual C
                    498: 
                    499:   Still problem with utsname.h on Windows
                    500: 
1.171     brouard   501:   Revision 1.170  2014/12/23 11:17:12  brouard
                    502:   Summary: Cleaning some \%% back to %%
                    503: 
                    504:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    505: 
1.170     brouard   506:   Revision 1.169  2014/12/22 23:08:31  brouard
                    507:   Summary: 0.98p
                    508: 
                    509:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    510: 
1.169     brouard   511:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   512:   Summary: update
1.169     brouard   513: 
1.168     brouard   514:   Revision 1.167  2014/12/22 13:50:56  brouard
                    515:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    516: 
                    517:   Testing on Linux 64
                    518: 
1.167     brouard   519:   Revision 1.166  2014/12/22 11:40:47  brouard
                    520:   *** empty log message ***
                    521: 
1.166     brouard   522:   Revision 1.165  2014/12/16 11:20:36  brouard
                    523:   Summary: After compiling on Visual C
                    524: 
                    525:   * imach.c (Module): Merging 1.61 to 1.162
                    526: 
1.165     brouard   527:   Revision 1.164  2014/12/16 10:52:11  brouard
                    528:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    529: 
                    530:   * imach.c (Module): Merging 1.61 to 1.162
                    531: 
1.164     brouard   532:   Revision 1.163  2014/12/16 10:30:11  brouard
                    533:   * imach.c (Module): Merging 1.61 to 1.162
                    534: 
1.163     brouard   535:   Revision 1.162  2014/09/25 11:43:39  brouard
                    536:   Summary: temporary backup 0.99!
                    537: 
1.162     brouard   538:   Revision 1.1  2014/09/16 11:06:58  brouard
                    539:   Summary: With some code (wrong) for nlopt
                    540: 
                    541:   Author:
                    542: 
                    543:   Revision 1.161  2014/09/15 20:41:41  brouard
                    544:   Summary: Problem with macro SQR on Intel compiler
                    545: 
1.161     brouard   546:   Revision 1.160  2014/09/02 09:24:05  brouard
                    547:   *** empty log message ***
                    548: 
1.160     brouard   549:   Revision 1.159  2014/09/01 10:34:10  brouard
                    550:   Summary: WIN32
                    551:   Author: Brouard
                    552: 
1.159     brouard   553:   Revision 1.158  2014/08/27 17:11:51  brouard
                    554:   *** empty log message ***
                    555: 
1.158     brouard   556:   Revision 1.157  2014/08/27 16:26:55  brouard
                    557:   Summary: Preparing windows Visual studio version
                    558:   Author: Brouard
                    559: 
                    560:   In order to compile on Visual studio, time.h is now correct and time_t
                    561:   and tm struct should be used. difftime should be used but sometimes I
                    562:   just make the differences in raw time format (time(&now).
                    563:   Trying to suppress #ifdef LINUX
                    564:   Add xdg-open for __linux in order to open default browser.
                    565: 
1.157     brouard   566:   Revision 1.156  2014/08/25 20:10:10  brouard
                    567:   *** empty log message ***
                    568: 
1.156     brouard   569:   Revision 1.155  2014/08/25 18:32:34  brouard
                    570:   Summary: New compile, minor changes
                    571:   Author: Brouard
                    572: 
1.155     brouard   573:   Revision 1.154  2014/06/20 17:32:08  brouard
                    574:   Summary: Outputs now all graphs of convergence to period prevalence
                    575: 
1.154     brouard   576:   Revision 1.153  2014/06/20 16:45:46  brouard
                    577:   Summary: If 3 live state, convergence to period prevalence on same graph
                    578:   Author: Brouard
                    579: 
1.153     brouard   580:   Revision 1.152  2014/06/18 17:54:09  brouard
                    581:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    582: 
1.152     brouard   583:   Revision 1.151  2014/06/18 16:43:30  brouard
                    584:   *** empty log message ***
                    585: 
1.151     brouard   586:   Revision 1.150  2014/06/18 16:42:35  brouard
                    587:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    588:   Author: brouard
                    589: 
1.150     brouard   590:   Revision 1.149  2014/06/18 15:51:14  brouard
                    591:   Summary: Some fixes in parameter files errors
                    592:   Author: Nicolas Brouard
                    593: 
1.149     brouard   594:   Revision 1.148  2014/06/17 17:38:48  brouard
                    595:   Summary: Nothing new
                    596:   Author: Brouard
                    597: 
                    598:   Just a new packaging for OS/X version 0.98nS
                    599: 
1.148     brouard   600:   Revision 1.147  2014/06/16 10:33:11  brouard
                    601:   *** empty log message ***
                    602: 
1.147     brouard   603:   Revision 1.146  2014/06/16 10:20:28  brouard
                    604:   Summary: Merge
                    605:   Author: Brouard
                    606: 
                    607:   Merge, before building revised version.
                    608: 
1.146     brouard   609:   Revision 1.145  2014/06/10 21:23:15  brouard
                    610:   Summary: Debugging with valgrind
                    611:   Author: Nicolas Brouard
                    612: 
                    613:   Lot of changes in order to output the results with some covariates
                    614:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    615:   improve the code.
                    616:   No more memory valgrind error but a lot has to be done in order to
                    617:   continue the work of splitting the code into subroutines.
                    618:   Also, decodemodel has been improved. Tricode is still not
                    619:   optimal. nbcode should be improved. Documentation has been added in
                    620:   the source code.
                    621: 
1.144     brouard   622:   Revision 1.143  2014/01/26 09:45:38  brouard
                    623:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    624: 
                    625:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    626:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    627: 
1.143     brouard   628:   Revision 1.142  2014/01/26 03:57:36  brouard
                    629:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    630: 
                    631:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    632: 
1.142     brouard   633:   Revision 1.141  2014/01/26 02:42:01  brouard
                    634:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    635: 
1.141     brouard   636:   Revision 1.140  2011/09/02 10:37:54  brouard
                    637:   Summary: times.h is ok with mingw32 now.
                    638: 
1.140     brouard   639:   Revision 1.139  2010/06/14 07:50:17  brouard
                    640:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    641:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    642: 
1.139     brouard   643:   Revision 1.138  2010/04/30 18:19:40  brouard
                    644:   *** empty log message ***
                    645: 
1.138     brouard   646:   Revision 1.137  2010/04/29 18:11:38  brouard
                    647:   (Module): Checking covariates for more complex models
                    648:   than V1+V2. A lot of change to be done. Unstable.
                    649: 
1.137     brouard   650:   Revision 1.136  2010/04/26 20:30:53  brouard
                    651:   (Module): merging some libgsl code. Fixing computation
                    652:   of likelione (using inter/intrapolation if mle = 0) in order to
                    653:   get same likelihood as if mle=1.
                    654:   Some cleaning of code and comments added.
                    655: 
1.136     brouard   656:   Revision 1.135  2009/10/29 15:33:14  brouard
                    657:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    658: 
1.135     brouard   659:   Revision 1.134  2009/10/29 13:18:53  brouard
                    660:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    661: 
1.134     brouard   662:   Revision 1.133  2009/07/06 10:21:25  brouard
                    663:   just nforces
                    664: 
1.133     brouard   665:   Revision 1.132  2009/07/06 08:22:05  brouard
                    666:   Many tings
                    667: 
1.132     brouard   668:   Revision 1.131  2009/06/20 16:22:47  brouard
                    669:   Some dimensions resccaled
                    670: 
1.131     brouard   671:   Revision 1.130  2009/05/26 06:44:34  brouard
                    672:   (Module): Max Covariate is now set to 20 instead of 8. A
                    673:   lot of cleaning with variables initialized to 0. Trying to make
                    674:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    675: 
1.130     brouard   676:   Revision 1.129  2007/08/31 13:49:27  lievre
                    677:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    678: 
1.129     lievre    679:   Revision 1.128  2006/06/30 13:02:05  brouard
                    680:   (Module): Clarifications on computing e.j
                    681: 
1.128     brouard   682:   Revision 1.127  2006/04/28 18:11:50  brouard
                    683:   (Module): Yes the sum of survivors was wrong since
                    684:   imach-114 because nhstepm was no more computed in the age
                    685:   loop. Now we define nhstepma in the age loop.
                    686:   (Module): In order to speed up (in case of numerous covariates) we
                    687:   compute health expectancies (without variances) in a first step
                    688:   and then all the health expectancies with variances or standard
                    689:   deviation (needs data from the Hessian matrices) which slows the
                    690:   computation.
                    691:   In the future we should be able to stop the program is only health
                    692:   expectancies and graph are needed without standard deviations.
                    693: 
1.127     brouard   694:   Revision 1.126  2006/04/28 17:23:28  brouard
                    695:   (Module): Yes the sum of survivors was wrong since
                    696:   imach-114 because nhstepm was no more computed in the age
                    697:   loop. Now we define nhstepma in the age loop.
                    698:   Version 0.98h
                    699: 
1.126     brouard   700:   Revision 1.125  2006/04/04 15:20:31  lievre
                    701:   Errors in calculation of health expectancies. Age was not initialized.
                    702:   Forecasting file added.
                    703: 
                    704:   Revision 1.124  2006/03/22 17:13:53  lievre
                    705:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    706:   The log-likelihood is printed in the log file
                    707: 
                    708:   Revision 1.123  2006/03/20 10:52:43  brouard
                    709:   * imach.c (Module): <title> changed, corresponds to .htm file
                    710:   name. <head> headers where missing.
                    711: 
                    712:   * imach.c (Module): Weights can have a decimal point as for
                    713:   English (a comma might work with a correct LC_NUMERIC environment,
                    714:   otherwise the weight is truncated).
                    715:   Modification of warning when the covariates values are not 0 or
                    716:   1.
                    717:   Version 0.98g
                    718: 
                    719:   Revision 1.122  2006/03/20 09:45:41  brouard
                    720:   (Module): Weights can have a decimal point as for
                    721:   English (a comma might work with a correct LC_NUMERIC environment,
                    722:   otherwise the weight is truncated).
                    723:   Modification of warning when the covariates values are not 0 or
                    724:   1.
                    725:   Version 0.98g
                    726: 
                    727:   Revision 1.121  2006/03/16 17:45:01  lievre
                    728:   * imach.c (Module): Comments concerning covariates added
                    729: 
                    730:   * imach.c (Module): refinements in the computation of lli if
                    731:   status=-2 in order to have more reliable computation if stepm is
                    732:   not 1 month. Version 0.98f
                    733: 
                    734:   Revision 1.120  2006/03/16 15:10:38  lievre
                    735:   (Module): refinements in the computation of lli if
                    736:   status=-2 in order to have more reliable computation if stepm is
                    737:   not 1 month. Version 0.98f
                    738: 
                    739:   Revision 1.119  2006/03/15 17:42:26  brouard
                    740:   (Module): Bug if status = -2, the loglikelihood was
                    741:   computed as likelihood omitting the logarithm. Version O.98e
                    742: 
                    743:   Revision 1.118  2006/03/14 18:20:07  brouard
                    744:   (Module): varevsij Comments added explaining the second
                    745:   table of variances if popbased=1 .
                    746:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    747:   (Module): Function pstamp added
                    748:   (Module): Version 0.98d
                    749: 
                    750:   Revision 1.117  2006/03/14 17:16:22  brouard
                    751:   (Module): varevsij Comments added explaining the second
                    752:   table of variances if popbased=1 .
                    753:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    754:   (Module): Function pstamp added
                    755:   (Module): Version 0.98d
                    756: 
                    757:   Revision 1.116  2006/03/06 10:29:27  brouard
                    758:   (Module): Variance-covariance wrong links and
                    759:   varian-covariance of ej. is needed (Saito).
                    760: 
                    761:   Revision 1.115  2006/02/27 12:17:45  brouard
                    762:   (Module): One freematrix added in mlikeli! 0.98c
                    763: 
                    764:   Revision 1.114  2006/02/26 12:57:58  brouard
                    765:   (Module): Some improvements in processing parameter
                    766:   filename with strsep.
                    767: 
                    768:   Revision 1.113  2006/02/24 14:20:24  brouard
                    769:   (Module): Memory leaks checks with valgrind and:
                    770:   datafile was not closed, some imatrix were not freed and on matrix
                    771:   allocation too.
                    772: 
                    773:   Revision 1.112  2006/01/30 09:55:26  brouard
                    774:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    775: 
                    776:   Revision 1.111  2006/01/25 20:38:18  brouard
                    777:   (Module): Lots of cleaning and bugs added (Gompertz)
                    778:   (Module): Comments can be added in data file. Missing date values
                    779:   can be a simple dot '.'.
                    780: 
                    781:   Revision 1.110  2006/01/25 00:51:50  brouard
                    782:   (Module): Lots of cleaning and bugs added (Gompertz)
                    783: 
                    784:   Revision 1.109  2006/01/24 19:37:15  brouard
                    785:   (Module): Comments (lines starting with a #) are allowed in data.
                    786: 
                    787:   Revision 1.108  2006/01/19 18:05:42  lievre
                    788:   Gnuplot problem appeared...
                    789:   To be fixed
                    790: 
                    791:   Revision 1.107  2006/01/19 16:20:37  brouard
                    792:   Test existence of gnuplot in imach path
                    793: 
                    794:   Revision 1.106  2006/01/19 13:24:36  brouard
                    795:   Some cleaning and links added in html output
                    796: 
                    797:   Revision 1.105  2006/01/05 20:23:19  lievre
                    798:   *** empty log message ***
                    799: 
                    800:   Revision 1.104  2005/09/30 16:11:43  lievre
                    801:   (Module): sump fixed, loop imx fixed, and simplifications.
                    802:   (Module): If the status is missing at the last wave but we know
                    803:   that the person is alive, then we can code his/her status as -2
                    804:   (instead of missing=-1 in earlier versions) and his/her
                    805:   contributions to the likelihood is 1 - Prob of dying from last
                    806:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    807:   the healthy state at last known wave). Version is 0.98
                    808: 
                    809:   Revision 1.103  2005/09/30 15:54:49  lievre
                    810:   (Module): sump fixed, loop imx fixed, and simplifications.
                    811: 
                    812:   Revision 1.102  2004/09/15 17:31:30  brouard
                    813:   Add the possibility to read data file including tab characters.
                    814: 
                    815:   Revision 1.101  2004/09/15 10:38:38  brouard
                    816:   Fix on curr_time
                    817: 
                    818:   Revision 1.100  2004/07/12 18:29:06  brouard
                    819:   Add version for Mac OS X. Just define UNIX in Makefile
                    820: 
                    821:   Revision 1.99  2004/06/05 08:57:40  brouard
                    822:   *** empty log message ***
                    823: 
                    824:   Revision 1.98  2004/05/16 15:05:56  brouard
                    825:   New version 0.97 . First attempt to estimate force of mortality
                    826:   directly from the data i.e. without the need of knowing the health
                    827:   state at each age, but using a Gompertz model: log u =a + b*age .
                    828:   This is the basic analysis of mortality and should be done before any
                    829:   other analysis, in order to test if the mortality estimated from the
                    830:   cross-longitudinal survey is different from the mortality estimated
                    831:   from other sources like vital statistic data.
                    832: 
                    833:   The same imach parameter file can be used but the option for mle should be -3.
                    834: 
1.133     brouard   835:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   836:   former routines in order to include the new code within the former code.
                    837: 
                    838:   The output is very simple: only an estimate of the intercept and of
                    839:   the slope with 95% confident intervals.
                    840: 
                    841:   Current limitations:
                    842:   A) Even if you enter covariates, i.e. with the
                    843:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    844:   B) There is no computation of Life Expectancy nor Life Table.
                    845: 
                    846:   Revision 1.97  2004/02/20 13:25:42  lievre
                    847:   Version 0.96d. Population forecasting command line is (temporarily)
                    848:   suppressed.
                    849: 
                    850:   Revision 1.96  2003/07/15 15:38:55  brouard
                    851:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    852:   rewritten within the same printf. Workaround: many printfs.
                    853: 
                    854:   Revision 1.95  2003/07/08 07:54:34  brouard
                    855:   * imach.c (Repository):
                    856:   (Repository): Using imachwizard code to output a more meaningful covariance
                    857:   matrix (cov(a12,c31) instead of numbers.
                    858: 
                    859:   Revision 1.94  2003/06/27 13:00:02  brouard
                    860:   Just cleaning
                    861: 
                    862:   Revision 1.93  2003/06/25 16:33:55  brouard
                    863:   (Module): On windows (cygwin) function asctime_r doesn't
                    864:   exist so I changed back to asctime which exists.
                    865:   (Module): Version 0.96b
                    866: 
                    867:   Revision 1.92  2003/06/25 16:30:45  brouard
                    868:   (Module): On windows (cygwin) function asctime_r doesn't
                    869:   exist so I changed back to asctime which exists.
                    870: 
                    871:   Revision 1.91  2003/06/25 15:30:29  brouard
                    872:   * imach.c (Repository): Duplicated warning errors corrected.
                    873:   (Repository): Elapsed time after each iteration is now output. It
                    874:   helps to forecast when convergence will be reached. Elapsed time
                    875:   is stamped in powell.  We created a new html file for the graphs
                    876:   concerning matrix of covariance. It has extension -cov.htm.
                    877: 
                    878:   Revision 1.90  2003/06/24 12:34:15  brouard
                    879:   (Module): Some bugs corrected for windows. Also, when
                    880:   mle=-1 a template is output in file "or"mypar.txt with the design
                    881:   of the covariance matrix to be input.
                    882: 
                    883:   Revision 1.89  2003/06/24 12:30:52  brouard
                    884:   (Module): Some bugs corrected for windows. Also, when
                    885:   mle=-1 a template is output in file "or"mypar.txt with the design
                    886:   of the covariance matrix to be input.
                    887: 
                    888:   Revision 1.88  2003/06/23 17:54:56  brouard
                    889:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    890: 
                    891:   Revision 1.87  2003/06/18 12:26:01  brouard
                    892:   Version 0.96
                    893: 
                    894:   Revision 1.86  2003/06/17 20:04:08  brouard
                    895:   (Module): Change position of html and gnuplot routines and added
                    896:   routine fileappend.
                    897: 
                    898:   Revision 1.85  2003/06/17 13:12:43  brouard
                    899:   * imach.c (Repository): Check when date of death was earlier that
                    900:   current date of interview. It may happen when the death was just
                    901:   prior to the death. In this case, dh was negative and likelihood
                    902:   was wrong (infinity). We still send an "Error" but patch by
                    903:   assuming that the date of death was just one stepm after the
                    904:   interview.
                    905:   (Repository): Because some people have very long ID (first column)
                    906:   we changed int to long in num[] and we added a new lvector for
                    907:   memory allocation. But we also truncated to 8 characters (left
                    908:   truncation)
                    909:   (Repository): No more line truncation errors.
                    910: 
                    911:   Revision 1.84  2003/06/13 21:44:43  brouard
                    912:   * imach.c (Repository): Replace "freqsummary" at a correct
                    913:   place. It differs from routine "prevalence" which may be called
                    914:   many times. Probs is memory consuming and must be used with
                    915:   parcimony.
                    916:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    917: 
                    918:   Revision 1.83  2003/06/10 13:39:11  lievre
                    919:   *** empty log message ***
                    920: 
                    921:   Revision 1.82  2003/06/05 15:57:20  brouard
                    922:   Add log in  imach.c and  fullversion number is now printed.
                    923: 
                    924: */
                    925: /*
                    926:    Interpolated Markov Chain
                    927: 
                    928:   Short summary of the programme:
                    929:   
1.227     brouard   930:   This program computes Healthy Life Expectancies or State-specific
                    931:   (if states aren't health statuses) Expectancies from
                    932:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    933: 
                    934:   -1- a first survey ("cross") where individuals from different ages
                    935:   are interviewed on their health status or degree of disability (in
                    936:   the case of a health survey which is our main interest)
                    937: 
                    938:   -2- at least a second wave of interviews ("longitudinal") which
                    939:   measure each change (if any) in individual health status.  Health
                    940:   expectancies are computed from the time spent in each health state
                    941:   according to a model. More health states you consider, more time is
                    942:   necessary to reach the Maximum Likelihood of the parameters involved
                    943:   in the model.  The simplest model is the multinomial logistic model
                    944:   where pij is the probability to be observed in state j at the second
                    945:   wave conditional to be observed in state i at the first
                    946:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    947:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    948:   have a more complex model than "constant and age", you should modify
                    949:   the program where the markup *Covariates have to be included here
                    950:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   951:   convergence.
                    952: 
                    953:   The advantage of this computer programme, compared to a simple
                    954:   multinomial logistic model, is clear when the delay between waves is not
                    955:   identical for each individual. Also, if a individual missed an
                    956:   intermediate interview, the information is lost, but taken into
                    957:   account using an interpolation or extrapolation.  
                    958: 
                    959:   hPijx is the probability to be observed in state i at age x+h
                    960:   conditional to the observed state i at age x. The delay 'h' can be
                    961:   split into an exact number (nh*stepm) of unobserved intermediate
                    962:   states. This elementary transition (by month, quarter,
                    963:   semester or year) is modelled as a multinomial logistic.  The hPx
                    964:   matrix is simply the matrix product of nh*stepm elementary matrices
                    965:   and the contribution of each individual to the likelihood is simply
                    966:   hPijx.
                    967: 
                    968:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   969:   of the life expectancies. It also computes the period (stable) prevalence.
                    970: 
                    971: Back prevalence and projections:
1.227     brouard   972: 
                    973:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    974:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    975:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    976:    mobilavproj)
                    977: 
                    978:     Computes the back prevalence limit for any combination of
                    979:     covariate values k at any age between ageminpar and agemaxpar and
                    980:     returns it in **bprlim. In the loops,
                    981: 
                    982:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    983:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    984: 
                    985:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   986:    Computes for any combination of covariates k and any age between bage and fage 
                    987:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    988:                        oldm=oldms;savm=savms;
1.227     brouard   989: 
1.267     brouard   990:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   991:      Computes the transition matrix starting at age 'age' over
                    992:      'nhstepm*hstepm*stepm' months (i.e. until
                    993:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   994:      nhstepm*hstepm matrices. 
                    995: 
                    996:      Returns p3mat[i][j][h] after calling
                    997:      p3mat[i][j][h]=matprod2(newm,
                    998:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    999:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                   1000:      oldm);
1.226     brouard  1001: 
                   1002: Important routines
                   1003: 
                   1004: - func (or funcone), computes logit (pij) distinguishing
                   1005:   o fixed variables (single or product dummies or quantitative);
                   1006:   o varying variables by:
                   1007:    (1) wave (single, product dummies, quantitative), 
                   1008:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                   1009:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                   1010:        % varying dummy (not done) or quantitative (not done);
                   1011: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                   1012:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                   1013: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                   1014:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                   1015:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard  1016: 
1.226     brouard  1017: 
                   1018:   
1.133     brouard  1019:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                   1020:            Institut national d'études démographiques, Paris.
1.126     brouard  1021:   This software have been partly granted by Euro-REVES, a concerted action
                   1022:   from the European Union.
                   1023:   It is copyrighted identically to a GNU software product, ie programme and
                   1024:   software can be distributed freely for non commercial use. Latest version
                   1025:   can be accessed at http://euroreves.ined.fr/imach .
                   1026: 
                   1027:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                   1028:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                   1029:   
                   1030:   **********************************************************************/
                   1031: /*
                   1032:   main
                   1033:   read parameterfile
                   1034:   read datafile
                   1035:   concatwav
                   1036:   freqsummary
                   1037:   if (mle >= 1)
                   1038:     mlikeli
                   1039:   print results files
                   1040:   if mle==1 
                   1041:      computes hessian
                   1042:   read end of parameter file: agemin, agemax, bage, fage, estepm
                   1043:       begin-prev-date,...
                   1044:   open gnuplot file
                   1045:   open html file
1.145     brouard  1046:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                   1047:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                   1048:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                   1049:     freexexit2 possible for memory heap.
                   1050: 
                   1051:   h Pij x                         | pij_nom  ficrestpij
                   1052:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                   1053:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                   1054:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                   1055: 
                   1056:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                   1057:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                   1058:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                   1059:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                   1060:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                   1061: 
1.126     brouard  1062:   forecasting if prevfcast==1 prevforecast call prevalence()
                   1063:   health expectancies
                   1064:   Variance-covariance of DFLE
                   1065:   prevalence()
                   1066:    movingaverage()
                   1067:   varevsij() 
                   1068:   if popbased==1 varevsij(,popbased)
                   1069:   total life expectancies
                   1070:   Variance of period (stable) prevalence
                   1071:  end
                   1072: */
                   1073: 
1.187     brouard  1074: /* #define DEBUG */
                   1075: /* #define DEBUGBRENT */
1.203     brouard  1076: /* #define DEBUGLINMIN */
                   1077: /* #define DEBUGHESS */
                   1078: #define DEBUGHESSIJ
1.224     brouard  1079: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard  1080: #define POWELL /* Instead of NLOPT */
1.224     brouard  1081: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard  1082: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                   1083: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard  1084: 
                   1085: #include <math.h>
                   1086: #include <stdio.h>
                   1087: #include <stdlib.h>
                   1088: #include <string.h>
1.226     brouard  1089: #include <ctype.h>
1.159     brouard  1090: 
                   1091: #ifdef _WIN32
                   1092: #include <io.h>
1.172     brouard  1093: #include <windows.h>
                   1094: #include <tchar.h>
1.159     brouard  1095: #else
1.126     brouard  1096: #include <unistd.h>
1.159     brouard  1097: #endif
1.126     brouard  1098: 
                   1099: #include <limits.h>
                   1100: #include <sys/types.h>
1.171     brouard  1101: 
                   1102: #if defined(__GNUC__)
                   1103: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1104: #endif
                   1105: 
1.126     brouard  1106: #include <sys/stat.h>
                   1107: #include <errno.h>
1.159     brouard  1108: /* extern int errno; */
1.126     brouard  1109: 
1.157     brouard  1110: /* #ifdef LINUX */
                   1111: /* #include <time.h> */
                   1112: /* #include "timeval.h" */
                   1113: /* #else */
                   1114: /* #include <sys/time.h> */
                   1115: /* #endif */
                   1116: 
1.126     brouard  1117: #include <time.h>
                   1118: 
1.136     brouard  1119: #ifdef GSL
                   1120: #include <gsl/gsl_errno.h>
                   1121: #include <gsl/gsl_multimin.h>
                   1122: #endif
                   1123: 
1.167     brouard  1124: 
1.162     brouard  1125: #ifdef NLOPT
                   1126: #include <nlopt.h>
                   1127: typedef struct {
                   1128:   double (* function)(double [] );
                   1129: } myfunc_data ;
                   1130: #endif
                   1131: 
1.126     brouard  1132: /* #include <libintl.h> */
                   1133: /* #define _(String) gettext (String) */
                   1134: 
1.251     brouard  1135: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1136: 
                   1137: #define GNUPLOTPROGRAM "gnuplot"
                   1138: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1139: #define FILENAMELENGTH 132
                   1140: 
                   1141: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1142: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1143: 
1.144     brouard  1144: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1145: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1146: 
                   1147: #define NINTERVMAX 8
1.144     brouard  1148: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1149: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.291     brouard  1150: #define NCOVMAX 20  /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1151: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1152: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1153: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1154: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1155: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1156: /* #define AGESUP 130 */
1.288     brouard  1157: /* #define AGESUP 150 */
                   1158: #define AGESUP 200
1.268     brouard  1159: #define AGEINF 0
1.218     brouard  1160: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1161: #define AGEBASE 40
1.194     brouard  1162: #define AGEOVERFLOW 1.e20
1.164     brouard  1163: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1164: #ifdef _WIN32
                   1165: #define DIRSEPARATOR '\\'
                   1166: #define CHARSEPARATOR "\\"
                   1167: #define ODIRSEPARATOR '/'
                   1168: #else
1.126     brouard  1169: #define DIRSEPARATOR '/'
                   1170: #define CHARSEPARATOR "/"
                   1171: #define ODIRSEPARATOR '\\'
                   1172: #endif
                   1173: 
1.313   ! brouard  1174: /* $Id: imach.c,v 1.312 2022/04/05 21:24:39 brouard Exp $ */
1.126     brouard  1175: /* $State: Exp $ */
1.196     brouard  1176: #include "version.h"
                   1177: char version[]=__IMACH_VERSION__;
1.308     brouard  1178: char copyright[]="March 2021,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2020, Nihon University 2021, INED 2000-2021";
1.313   ! brouard  1179: char fullversion[]="$Revision: 1.312 $ $Date: 2022/04/05 21:24:39 $"; 
1.126     brouard  1180: char strstart[80];
                   1181: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1182: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1183: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1184: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1185: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1186: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1187: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1188: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1189: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1190: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1191: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1192: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1193: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1194: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1195: int nsd=0; /**< Total number of single dummy variables (output) */
                   1196: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1197: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1198: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1199: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1200: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1201: int cptcov=0; /* Working variable */
1.290     brouard  1202: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1203: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.302     brouard  1204: int npar=NPARMAX; /* Number of parameters (nlstate+ndeath-1)*nlstate*ncovmodel; */
1.126     brouard  1205: int nlstate=2; /* Number of live states */
                   1206: int ndeath=1; /* Number of dead states */
1.130     brouard  1207: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1208: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1209: int popbased=0;
                   1210: 
                   1211: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1212: int maxwav=0; /* Maxim number of waves */
                   1213: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1214: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1215: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1216:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1217: int mle=1, weightopt=0;
1.126     brouard  1218: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1219: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1220: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1221:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1222: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1223: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1224: 
1.130     brouard  1225: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1226: double **matprod2(); /* test */
1.126     brouard  1227: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1228: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1229: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1230: 
1.136     brouard  1231: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1232: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1233: FILE *ficlog, *ficrespow;
1.130     brouard  1234: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1235: double fretone; /* Only one call to likelihood */
1.130     brouard  1236: long ipmx=0; /* Number of contributions */
1.126     brouard  1237: double sw; /* Sum of weights */
                   1238: char filerespow[FILENAMELENGTH];
                   1239: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1240: FILE *ficresilk;
                   1241: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1242: FILE *ficresprobmorprev;
                   1243: FILE *fichtm, *fichtmcov; /* Html File */
                   1244: FILE *ficreseij;
                   1245: char filerese[FILENAMELENGTH];
                   1246: FILE *ficresstdeij;
                   1247: char fileresstde[FILENAMELENGTH];
                   1248: FILE *ficrescveij;
                   1249: char filerescve[FILENAMELENGTH];
                   1250: FILE  *ficresvij;
                   1251: char fileresv[FILENAMELENGTH];
1.269     brouard  1252: 
1.126     brouard  1253: char title[MAXLINE];
1.234     brouard  1254: char model[MAXLINE]; /**< The model line */
1.217     brouard  1255: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1256: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1257: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1258: char command[FILENAMELENGTH];
                   1259: int  outcmd=0;
                   1260: 
1.217     brouard  1261: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1262: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1263: char filelog[FILENAMELENGTH]; /* Log file */
                   1264: char filerest[FILENAMELENGTH];
                   1265: char fileregp[FILENAMELENGTH];
                   1266: char popfile[FILENAMELENGTH];
                   1267: 
                   1268: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1269: 
1.157     brouard  1270: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1271: /* struct timezone tzp; */
                   1272: /* extern int gettimeofday(); */
                   1273: struct tm tml, *gmtime(), *localtime();
                   1274: 
                   1275: extern time_t time();
                   1276: 
                   1277: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1278: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1279: struct tm tm;
                   1280: 
1.126     brouard  1281: char strcurr[80], strfor[80];
                   1282: 
                   1283: char *endptr;
                   1284: long lval;
                   1285: double dval;
                   1286: 
                   1287: #define NR_END 1
                   1288: #define FREE_ARG char*
                   1289: #define FTOL 1.0e-10
                   1290: 
                   1291: #define NRANSI 
1.240     brouard  1292: #define ITMAX 200
                   1293: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1294: 
                   1295: #define TOL 2.0e-4 
                   1296: 
                   1297: #define CGOLD 0.3819660 
                   1298: #define ZEPS 1.0e-10 
                   1299: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1300: 
                   1301: #define GOLD 1.618034 
                   1302: #define GLIMIT 100.0 
                   1303: #define TINY 1.0e-20 
                   1304: 
                   1305: static double maxarg1,maxarg2;
                   1306: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1307: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1308:   
                   1309: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1310: #define rint(a) floor(a+0.5)
1.166     brouard  1311: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1312: #define mytinydouble 1.0e-16
1.166     brouard  1313: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1314: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1315: /* static double dsqrarg; */
                   1316: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1317: static double sqrarg;
                   1318: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1319: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1320: int agegomp= AGEGOMP;
                   1321: 
                   1322: int imx; 
                   1323: int stepm=1;
                   1324: /* Stepm, step in month: minimum step interpolation*/
                   1325: 
                   1326: int estepm;
                   1327: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1328: 
                   1329: int m,nb;
                   1330: long *num;
1.197     brouard  1331: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1332: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1333:                   covariate for which somebody answered excluding 
                   1334:                   undefined. Usually 2: 0 and 1. */
                   1335: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1336:                             covariate for which somebody answered including 
                   1337:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1338: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1339: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1340: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1341: double *ageexmed,*agecens;
                   1342: double dateintmean=0;
1.296     brouard  1343:   double anprojd, mprojd, jprojd; /* For eventual projections */
                   1344:   double anprojf, mprojf, jprojf;
1.126     brouard  1345: 
1.296     brouard  1346:   double anbackd, mbackd, jbackd; /* For eventual backprojections */
                   1347:   double anbackf, mbackf, jbackf;
                   1348:   double jintmean,mintmean,aintmean;  
1.126     brouard  1349: double *weight;
                   1350: int **s; /* Status */
1.141     brouard  1351: double *agedc;
1.145     brouard  1352: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1353:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1354:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1355: double **coqvar; /* Fixed quantitative covariate nqv */
                   1356: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1357: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1358: double  idx; 
                   1359: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1360: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1361: /*k          1  2   3   4     5    6    7     8    9 */
                   1362: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1363: /* Tndvar[k]    1   2   3               4          5 */
                   1364: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1365: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1366: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1367: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1368: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1369: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1370: /* Tprod[i]=k           4               7            */
                   1371: /* Tage[i]=k                  5               8      */
                   1372: /* */
                   1373: /* Type                    */
                   1374: /* V         1  2  3  4  5 */
                   1375: /*           F  F  V  V  V */
                   1376: /*           D  Q  D  D  Q */
                   1377: /*                         */
                   1378: int *TvarsD;
                   1379: int *TvarsDind;
                   1380: int *TvarsQ;
                   1381: int *TvarsQind;
                   1382: 
1.235     brouard  1383: #define MAXRESULTLINES 10
                   1384: int nresult=0;
1.258     brouard  1385: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1386: int TKresult[MAXRESULTLINES];
1.237     brouard  1387: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1388: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1389: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1390: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1391: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1392: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1393: 
1.234     brouard  1394: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1395: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1396: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1397: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1398: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1399: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1400: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1401: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1402: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1403: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1404: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1405: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1406: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1407: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1408: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1409: 
1.230     brouard  1410: int *Tvarsel; /**< Selected covariates for output */
                   1411: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1412: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1413: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1414: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1415: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1416: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1417: int *Tage;
1.227     brouard  1418: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1419: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1420: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1421: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1422: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1423: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1424: int **Tvard;
                   1425: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1426: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1427: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1428:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1429:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1430: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1431: double *lsurv, *lpop, *tpop;
                   1432: 
1.231     brouard  1433: #define FD 1; /* Fixed dummy covariate */
                   1434: #define FQ 2; /* Fixed quantitative covariate */
                   1435: #define FP 3; /* Fixed product covariate */
                   1436: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1437: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1438: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1439: #define VD 10; /* Varying dummy covariate */
                   1440: #define VQ 11; /* Varying quantitative covariate */
                   1441: #define VP 12; /* Varying product covariate */
                   1442: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1443: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1444: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1445: #define APFD 16; /* Age product * fixed dummy covariate */
                   1446: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1447: #define APVD 18; /* Age product * varying dummy covariate */
                   1448: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1449: 
                   1450: #define FTYPE 1; /* Fixed covariate */
                   1451: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1452: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1453: 
                   1454: struct kmodel{
                   1455:        int maintype; /* main type */
                   1456:        int subtype; /* subtype */
                   1457: };
                   1458: struct kmodel modell[NCOVMAX];
                   1459: 
1.143     brouard  1460: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1461: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1462: 
                   1463: /**************** split *************************/
                   1464: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1465: {
                   1466:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1467:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1468:   */ 
                   1469:   char *ss;                            /* pointer */
1.186     brouard  1470:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1471: 
                   1472:   l1 = strlen(path );                  /* length of path */
                   1473:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1474:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1475:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1476:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1477:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1478:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1479:     /* get current working directory */
                   1480:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1481: #ifdef WIN32
                   1482:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1483: #else
                   1484:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1485: #endif
1.126     brouard  1486:       return( GLOCK_ERROR_GETCWD );
                   1487:     }
                   1488:     /* got dirc from getcwd*/
                   1489:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1490:   } else {                             /* strip directory from path */
1.126     brouard  1491:     ss++;                              /* after this, the filename */
                   1492:     l2 = strlen( ss );                 /* length of filename */
                   1493:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1494:     strcpy( name, ss );                /* save file name */
                   1495:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1496:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1497:     printf(" DIRC2 = %s \n",dirc);
                   1498:   }
                   1499:   /* We add a separator at the end of dirc if not exists */
                   1500:   l1 = strlen( dirc );                 /* length of directory */
                   1501:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1502:     dirc[l1] =  DIRSEPARATOR;
                   1503:     dirc[l1+1] = 0; 
                   1504:     printf(" DIRC3 = %s \n",dirc);
                   1505:   }
                   1506:   ss = strrchr( name, '.' );           /* find last / */
                   1507:   if (ss >0){
                   1508:     ss++;
                   1509:     strcpy(ext,ss);                    /* save extension */
                   1510:     l1= strlen( name);
                   1511:     l2= strlen(ss)+1;
                   1512:     strncpy( finame, name, l1-l2);
                   1513:     finame[l1-l2]= 0;
                   1514:   }
                   1515: 
                   1516:   return( 0 );                         /* we're done */
                   1517: }
                   1518: 
                   1519: 
                   1520: /******************************************/
                   1521: 
                   1522: void replace_back_to_slash(char *s, char*t)
                   1523: {
                   1524:   int i;
                   1525:   int lg=0;
                   1526:   i=0;
                   1527:   lg=strlen(t);
                   1528:   for(i=0; i<= lg; i++) {
                   1529:     (s[i] = t[i]);
                   1530:     if (t[i]== '\\') s[i]='/';
                   1531:   }
                   1532: }
                   1533: 
1.132     brouard  1534: char *trimbb(char *out, char *in)
1.137     brouard  1535: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1536:   char *s;
                   1537:   s=out;
                   1538:   while (*in != '\0'){
1.137     brouard  1539:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1540:       in++;
                   1541:     }
                   1542:     *out++ = *in++;
                   1543:   }
                   1544:   *out='\0';
                   1545:   return s;
                   1546: }
                   1547: 
1.187     brouard  1548: /* char *substrchaine(char *out, char *in, char *chain) */
                   1549: /* { */
                   1550: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1551: /*   char *s, *t; */
                   1552: /*   t=in;s=out; */
                   1553: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1554: /*     *out++ = *in++; */
                   1555: /*   } */
                   1556: 
                   1557: /*   /\* *in matches *chain *\/ */
                   1558: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1559: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1560: /*   } */
                   1561: /*   in--; chain--; */
                   1562: /*   while ( (*in != '\0')){ */
                   1563: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1564: /*     *out++ = *in++; */
                   1565: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1566: /*   } */
                   1567: /*   *out='\0'; */
                   1568: /*   out=s; */
                   1569: /*   return out; */
                   1570: /* } */
                   1571: char *substrchaine(char *out, char *in, char *chain)
                   1572: {
                   1573:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1574:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1575: 
                   1576:   char *strloc;
                   1577: 
                   1578:   strcpy (out, in); 
                   1579:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1580:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1581:   if(strloc != NULL){ 
                   1582:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1583:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1584:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1585:   }
                   1586:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1587:   return out;
                   1588: }
                   1589: 
                   1590: 
1.145     brouard  1591: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1592: {
1.187     brouard  1593:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1594:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.310     brouard  1595:      gives alocc="abcdef" and blocc="ghi2j".
1.145     brouard  1596:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1597:   */
1.160     brouard  1598:   char *s, *t;
1.145     brouard  1599:   t=in;s=in;
                   1600:   while ((*in != occ) && (*in != '\0')){
                   1601:     *alocc++ = *in++;
                   1602:   }
                   1603:   if( *in == occ){
                   1604:     *(alocc)='\0';
                   1605:     s=++in;
                   1606:   }
                   1607:  
                   1608:   if (s == t) {/* occ not found */
                   1609:     *(alocc-(in-s))='\0';
                   1610:     in=s;
                   1611:   }
                   1612:   while ( *in != '\0'){
                   1613:     *blocc++ = *in++;
                   1614:   }
                   1615: 
                   1616:   *blocc='\0';
                   1617:   return t;
                   1618: }
1.137     brouard  1619: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1620: {
1.187     brouard  1621:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1622:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1623:      gives blocc="abcdef2ghi" and alocc="j".
                   1624:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1625:   */
                   1626:   char *s, *t;
                   1627:   t=in;s=in;
                   1628:   while (*in != '\0'){
                   1629:     while( *in == occ){
                   1630:       *blocc++ = *in++;
                   1631:       s=in;
                   1632:     }
                   1633:     *blocc++ = *in++;
                   1634:   }
                   1635:   if (s == t) /* occ not found */
                   1636:     *(blocc-(in-s))='\0';
                   1637:   else
                   1638:     *(blocc-(in-s)-1)='\0';
                   1639:   in=s;
                   1640:   while ( *in != '\0'){
                   1641:     *alocc++ = *in++;
                   1642:   }
                   1643: 
                   1644:   *alocc='\0';
                   1645:   return s;
                   1646: }
                   1647: 
1.126     brouard  1648: int nbocc(char *s, char occ)
                   1649: {
                   1650:   int i,j=0;
                   1651:   int lg=20;
                   1652:   i=0;
                   1653:   lg=strlen(s);
                   1654:   for(i=0; i<= lg; i++) {
1.234     brouard  1655:     if  (s[i] == occ ) j++;
1.126     brouard  1656:   }
                   1657:   return j;
                   1658: }
                   1659: 
1.137     brouard  1660: /* void cutv(char *u,char *v, char*t, char occ) */
                   1661: /* { */
                   1662: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1663: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1664: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1665: /*   int i,lg,j,p=0; */
                   1666: /*   i=0; */
                   1667: /*   lg=strlen(t); */
                   1668: /*   for(j=0; j<=lg-1; j++) { */
                   1669: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1670: /*   } */
1.126     brouard  1671: 
1.137     brouard  1672: /*   for(j=0; j<p; j++) { */
                   1673: /*     (u[j] = t[j]); */
                   1674: /*   } */
                   1675: /*      u[p]='\0'; */
1.126     brouard  1676: 
1.137     brouard  1677: /*    for(j=0; j<= lg; j++) { */
                   1678: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1679: /*   } */
                   1680: /* } */
1.126     brouard  1681: 
1.160     brouard  1682: #ifdef _WIN32
                   1683: char * strsep(char **pp, const char *delim)
                   1684: {
                   1685:   char *p, *q;
                   1686:          
                   1687:   if ((p = *pp) == NULL)
                   1688:     return 0;
                   1689:   if ((q = strpbrk (p, delim)) != NULL)
                   1690:   {
                   1691:     *pp = q + 1;
                   1692:     *q = '\0';
                   1693:   }
                   1694:   else
                   1695:     *pp = 0;
                   1696:   return p;
                   1697: }
                   1698: #endif
                   1699: 
1.126     brouard  1700: /********************** nrerror ********************/
                   1701: 
                   1702: void nrerror(char error_text[])
                   1703: {
                   1704:   fprintf(stderr,"ERREUR ...\n");
                   1705:   fprintf(stderr,"%s\n",error_text);
                   1706:   exit(EXIT_FAILURE);
                   1707: }
                   1708: /*********************** vector *******************/
                   1709: double *vector(int nl, int nh)
                   1710: {
                   1711:   double *v;
                   1712:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1713:   if (!v) nrerror("allocation failure in vector");
                   1714:   return v-nl+NR_END;
                   1715: }
                   1716: 
                   1717: /************************ free vector ******************/
                   1718: void free_vector(double*v, int nl, int nh)
                   1719: {
                   1720:   free((FREE_ARG)(v+nl-NR_END));
                   1721: }
                   1722: 
                   1723: /************************ivector *******************************/
                   1724: int *ivector(long nl,long nh)
                   1725: {
                   1726:   int *v;
                   1727:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1728:   if (!v) nrerror("allocation failure in ivector");
                   1729:   return v-nl+NR_END;
                   1730: }
                   1731: 
                   1732: /******************free ivector **************************/
                   1733: void free_ivector(int *v, long nl, long nh)
                   1734: {
                   1735:   free((FREE_ARG)(v+nl-NR_END));
                   1736: }
                   1737: 
                   1738: /************************lvector *******************************/
                   1739: long *lvector(long nl,long nh)
                   1740: {
                   1741:   long *v;
                   1742:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1743:   if (!v) nrerror("allocation failure in ivector");
                   1744:   return v-nl+NR_END;
                   1745: }
                   1746: 
                   1747: /******************free lvector **************************/
                   1748: void free_lvector(long *v, long nl, long nh)
                   1749: {
                   1750:   free((FREE_ARG)(v+nl-NR_END));
                   1751: }
                   1752: 
                   1753: /******************* imatrix *******************************/
                   1754: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1755:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1756: { 
                   1757:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1758:   int **m; 
                   1759:   
                   1760:   /* allocate pointers to rows */ 
                   1761:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1762:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1763:   m += NR_END; 
                   1764:   m -= nrl; 
                   1765:   
                   1766:   
                   1767:   /* allocate rows and set pointers to them */ 
                   1768:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1769:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1770:   m[nrl] += NR_END; 
                   1771:   m[nrl] -= ncl; 
                   1772:   
                   1773:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1774:   
                   1775:   /* return pointer to array of pointers to rows */ 
                   1776:   return m; 
                   1777: } 
                   1778: 
                   1779: /****************** free_imatrix *************************/
                   1780: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1781:       int **m;
                   1782:       long nch,ncl,nrh,nrl; 
                   1783:      /* free an int matrix allocated by imatrix() */ 
                   1784: { 
                   1785:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1786:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1787: } 
                   1788: 
                   1789: /******************* matrix *******************************/
                   1790: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1791: {
                   1792:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1793:   double **m;
                   1794: 
                   1795:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1796:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1797:   m += NR_END;
                   1798:   m -= nrl;
                   1799: 
                   1800:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1801:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1802:   m[nrl] += NR_END;
                   1803:   m[nrl] -= ncl;
                   1804: 
                   1805:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1806:   return m;
1.145     brouard  1807:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1808: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1809: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1810:    */
                   1811: }
                   1812: 
                   1813: /*************************free matrix ************************/
                   1814: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1815: {
                   1816:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1817:   free((FREE_ARG)(m+nrl-NR_END));
                   1818: }
                   1819: 
                   1820: /******************* ma3x *******************************/
                   1821: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1822: {
                   1823:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1824:   double ***m;
                   1825: 
                   1826:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1827:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1828:   m += NR_END;
                   1829:   m -= nrl;
                   1830: 
                   1831:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1832:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1833:   m[nrl] += NR_END;
                   1834:   m[nrl] -= ncl;
                   1835: 
                   1836:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1837: 
                   1838:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1839:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1840:   m[nrl][ncl] += NR_END;
                   1841:   m[nrl][ncl] -= nll;
                   1842:   for (j=ncl+1; j<=nch; j++) 
                   1843:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1844:   
                   1845:   for (i=nrl+1; i<=nrh; i++) {
                   1846:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1847:     for (j=ncl+1; j<=nch; j++) 
                   1848:       m[i][j]=m[i][j-1]+nlay;
                   1849:   }
                   1850:   return m; 
                   1851:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1852:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1853:   */
                   1854: }
                   1855: 
                   1856: /*************************free ma3x ************************/
                   1857: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1858: {
                   1859:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1860:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1861:   free((FREE_ARG)(m+nrl-NR_END));
                   1862: }
                   1863: 
                   1864: /*************** function subdirf ***********/
                   1865: char *subdirf(char fileres[])
                   1866: {
                   1867:   /* Caution optionfilefiname is hidden */
                   1868:   strcpy(tmpout,optionfilefiname);
                   1869:   strcat(tmpout,"/"); /* Add to the right */
                   1870:   strcat(tmpout,fileres);
                   1871:   return tmpout;
                   1872: }
                   1873: 
                   1874: /*************** function subdirf2 ***********/
                   1875: char *subdirf2(char fileres[], char *preop)
                   1876: {
                   1877:   
                   1878:   /* Caution optionfilefiname is hidden */
                   1879:   strcpy(tmpout,optionfilefiname);
                   1880:   strcat(tmpout,"/");
                   1881:   strcat(tmpout,preop);
                   1882:   strcat(tmpout,fileres);
                   1883:   return tmpout;
                   1884: }
                   1885: 
                   1886: /*************** function subdirf3 ***********/
                   1887: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1888: {
                   1889:   
                   1890:   /* Caution optionfilefiname is hidden */
                   1891:   strcpy(tmpout,optionfilefiname);
                   1892:   strcat(tmpout,"/");
                   1893:   strcat(tmpout,preop);
                   1894:   strcat(tmpout,preop2);
                   1895:   strcat(tmpout,fileres);
                   1896:   return tmpout;
                   1897: }
1.213     brouard  1898:  
                   1899: /*************** function subdirfext ***********/
                   1900: char *subdirfext(char fileres[], char *preop, char *postop)
                   1901: {
                   1902:   
                   1903:   strcpy(tmpout,preop);
                   1904:   strcat(tmpout,fileres);
                   1905:   strcat(tmpout,postop);
                   1906:   return tmpout;
                   1907: }
1.126     brouard  1908: 
1.213     brouard  1909: /*************** function subdirfext3 ***********/
                   1910: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1911: {
                   1912:   
                   1913:   /* Caution optionfilefiname is hidden */
                   1914:   strcpy(tmpout,optionfilefiname);
                   1915:   strcat(tmpout,"/");
                   1916:   strcat(tmpout,preop);
                   1917:   strcat(tmpout,fileres);
                   1918:   strcat(tmpout,postop);
                   1919:   return tmpout;
                   1920: }
                   1921:  
1.162     brouard  1922: char *asc_diff_time(long time_sec, char ascdiff[])
                   1923: {
                   1924:   long sec_left, days, hours, minutes;
                   1925:   days = (time_sec) / (60*60*24);
                   1926:   sec_left = (time_sec) % (60*60*24);
                   1927:   hours = (sec_left) / (60*60) ;
                   1928:   sec_left = (sec_left) %(60*60);
                   1929:   minutes = (sec_left) /60;
                   1930:   sec_left = (sec_left) % (60);
                   1931:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1932:   return ascdiff;
                   1933: }
                   1934: 
1.126     brouard  1935: /***************** f1dim *************************/
                   1936: extern int ncom; 
                   1937: extern double *pcom,*xicom;
                   1938: extern double (*nrfunc)(double []); 
                   1939:  
                   1940: double f1dim(double x) 
                   1941: { 
                   1942:   int j; 
                   1943:   double f;
                   1944:   double *xt; 
                   1945:  
                   1946:   xt=vector(1,ncom); 
                   1947:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1948:   f=(*nrfunc)(xt); 
                   1949:   free_vector(xt,1,ncom); 
                   1950:   return f; 
                   1951: } 
                   1952: 
                   1953: /*****************brent *************************/
                   1954: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1955: {
                   1956:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1957:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1958:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1959:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1960:    * returned function value. 
                   1961:   */
1.126     brouard  1962:   int iter; 
                   1963:   double a,b,d,etemp;
1.159     brouard  1964:   double fu=0,fv,fw,fx;
1.164     brouard  1965:   double ftemp=0.;
1.126     brouard  1966:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1967:   double e=0.0; 
                   1968:  
                   1969:   a=(ax < cx ? ax : cx); 
                   1970:   b=(ax > cx ? ax : cx); 
                   1971:   x=w=v=bx; 
                   1972:   fw=fv=fx=(*f)(x); 
                   1973:   for (iter=1;iter<=ITMAX;iter++) { 
                   1974:     xm=0.5*(a+b); 
                   1975:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1976:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1977:     printf(".");fflush(stdout);
                   1978:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1979: #ifdef DEBUGBRENT
1.126     brouard  1980:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1981:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1982:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1983: #endif
                   1984:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1985:       *xmin=x; 
                   1986:       return fx; 
                   1987:     } 
                   1988:     ftemp=fu;
                   1989:     if (fabs(e) > tol1) { 
                   1990:       r=(x-w)*(fx-fv); 
                   1991:       q=(x-v)*(fx-fw); 
                   1992:       p=(x-v)*q-(x-w)*r; 
                   1993:       q=2.0*(q-r); 
                   1994:       if (q > 0.0) p = -p; 
                   1995:       q=fabs(q); 
                   1996:       etemp=e; 
                   1997:       e=d; 
                   1998:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1999:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  2000:       else { 
1.224     brouard  2001:                                d=p/q; 
                   2002:                                u=x+d; 
                   2003:                                if (u-a < tol2 || b-u < tol2) 
                   2004:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  2005:       } 
                   2006:     } else { 
                   2007:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   2008:     } 
                   2009:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   2010:     fu=(*f)(u); 
                   2011:     if (fu <= fx) { 
                   2012:       if (u >= x) a=x; else b=x; 
                   2013:       SHFT(v,w,x,u) 
1.183     brouard  2014:       SHFT(fv,fw,fx,fu) 
                   2015:     } else { 
                   2016:       if (u < x) a=u; else b=u; 
                   2017:       if (fu <= fw || w == x) { 
1.224     brouard  2018:                                v=w; 
                   2019:                                w=u; 
                   2020:                                fv=fw; 
                   2021:                                fw=fu; 
1.183     brouard  2022:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  2023:                                v=u; 
                   2024:                                fv=fu; 
1.183     brouard  2025:       } 
                   2026:     } 
1.126     brouard  2027:   } 
                   2028:   nrerror("Too many iterations in brent"); 
                   2029:   *xmin=x; 
                   2030:   return fx; 
                   2031: } 
                   2032: 
                   2033: /****************** mnbrak ***********************/
                   2034: 
                   2035: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   2036:            double (*func)(double)) 
1.183     brouard  2037: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   2038: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   2039: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   2040: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   2041:    */
1.126     brouard  2042:   double ulim,u,r,q, dum;
                   2043:   double fu; 
1.187     brouard  2044: 
                   2045:   double scale=10.;
                   2046:   int iterscale=0;
                   2047: 
                   2048:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   2049:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   2050: 
                   2051: 
                   2052:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   2053:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   2054:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   2055:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   2056:   /* } */
                   2057: 
1.126     brouard  2058:   if (*fb > *fa) { 
                   2059:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  2060:     SHFT(dum,*fb,*fa,dum) 
                   2061:   } 
1.126     brouard  2062:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   2063:   *fc=(*func)(*cx); 
1.183     brouard  2064: #ifdef DEBUG
1.224     brouard  2065:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   2066:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  2067: #endif
1.224     brouard  2068:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  2069:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  2070:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  2071:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  2072:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   2073:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   2074:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  2075:       fu=(*func)(u); 
1.163     brouard  2076: #ifdef DEBUG
                   2077:       /* f(x)=A(x-u)**2+f(u) */
                   2078:       double A, fparabu; 
                   2079:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2080:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  2081:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   2082:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  2083:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   2084:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   2085:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   2086:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  2087: #endif 
1.184     brouard  2088: #ifdef MNBRAKORIGINAL
1.183     brouard  2089: #else
1.191     brouard  2090: /*       if (fu > *fc) { */
                   2091: /* #ifdef DEBUG */
                   2092: /*       printf("mnbrak4  fu > fc \n"); */
                   2093: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   2094: /* #endif */
                   2095: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   2096: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   2097: /*     dum=u; /\* Shifting c and u *\/ */
                   2098: /*     u = *cx; */
                   2099: /*     *cx = dum; */
                   2100: /*     dum = fu; */
                   2101: /*     fu = *fc; */
                   2102: /*     *fc =dum; */
                   2103: /*       } else { /\* end *\/ */
                   2104: /* #ifdef DEBUG */
                   2105: /*       printf("mnbrak3  fu < fc \n"); */
                   2106: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2107: /* #endif */
                   2108: /*     dum=u; /\* Shifting c and u *\/ */
                   2109: /*     u = *cx; */
                   2110: /*     *cx = dum; */
                   2111: /*     dum = fu; */
                   2112: /*     fu = *fc; */
                   2113: /*     *fc =dum; */
                   2114: /*       } */
1.224     brouard  2115: #ifdef DEBUGMNBRAK
                   2116:                 double A, fparabu; 
                   2117:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2118:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2119:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2120:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2121: #endif
1.191     brouard  2122:       dum=u; /* Shifting c and u */
                   2123:       u = *cx;
                   2124:       *cx = dum;
                   2125:       dum = fu;
                   2126:       fu = *fc;
                   2127:       *fc =dum;
1.183     brouard  2128: #endif
1.162     brouard  2129:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2130: #ifdef DEBUG
1.224     brouard  2131:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2132:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2133: #endif
1.126     brouard  2134:       fu=(*func)(u); 
                   2135:       if (fu < *fc) { 
1.183     brouard  2136: #ifdef DEBUG
1.224     brouard  2137:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2138:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2139: #endif
                   2140:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2141:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2142: #ifdef DEBUG
                   2143:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2144: #endif
                   2145:       } 
1.162     brouard  2146:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2147: #ifdef DEBUG
1.224     brouard  2148:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2149:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2150: #endif
1.126     brouard  2151:       u=ulim; 
                   2152:       fu=(*func)(u); 
1.183     brouard  2153:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2154: #ifdef DEBUG
1.224     brouard  2155:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2156:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2157: #endif
1.126     brouard  2158:       u=(*cx)+GOLD*(*cx-*bx); 
                   2159:       fu=(*func)(u); 
1.224     brouard  2160: #ifdef DEBUG
                   2161:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2162:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2163: #endif
1.183     brouard  2164:     } /* end tests */
1.126     brouard  2165:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2166:     SHFT(*fa,*fb,*fc,fu) 
                   2167: #ifdef DEBUG
1.224     brouard  2168:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2169:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2170: #endif
                   2171:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2172: } 
                   2173: 
                   2174: /*************** linmin ************************/
1.162     brouard  2175: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2176: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2177: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2178: the value of func at the returned location p . This is actually all accomplished by calling the
                   2179: routines mnbrak and brent .*/
1.126     brouard  2180: int ncom; 
                   2181: double *pcom,*xicom;
                   2182: double (*nrfunc)(double []); 
                   2183:  
1.224     brouard  2184: #ifdef LINMINORIGINAL
1.126     brouard  2185: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2186: #else
                   2187: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2188: #endif
1.126     brouard  2189: { 
                   2190:   double brent(double ax, double bx, double cx, 
                   2191:               double (*f)(double), double tol, double *xmin); 
                   2192:   double f1dim(double x); 
                   2193:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2194:              double *fc, double (*func)(double)); 
                   2195:   int j; 
                   2196:   double xx,xmin,bx,ax; 
                   2197:   double fx,fb,fa;
1.187     brouard  2198: 
1.203     brouard  2199: #ifdef LINMINORIGINAL
                   2200: #else
                   2201:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2202: #endif
                   2203:   
1.126     brouard  2204:   ncom=n; 
                   2205:   pcom=vector(1,n); 
                   2206:   xicom=vector(1,n); 
                   2207:   nrfunc=func; 
                   2208:   for (j=1;j<=n;j++) { 
                   2209:     pcom[j]=p[j]; 
1.202     brouard  2210:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2211:   } 
1.187     brouard  2212: 
1.203     brouard  2213: #ifdef LINMINORIGINAL
                   2214:   xx=1.;
                   2215: #else
                   2216:   axs=0.0;
                   2217:   xxs=1.;
                   2218:   do{
                   2219:     xx= xxs;
                   2220: #endif
1.187     brouard  2221:     ax=0.;
                   2222:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2223:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2224:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2225:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2226:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2227:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2228:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2229: #ifdef LINMINORIGINAL
                   2230: #else
                   2231:     if (fx != fx){
1.224     brouard  2232:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2233:                        printf("|");
                   2234:                        fprintf(ficlog,"|");
1.203     brouard  2235: #ifdef DEBUGLINMIN
1.224     brouard  2236:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2237: #endif
                   2238:     }
1.224     brouard  2239:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2240: #endif
                   2241:   
1.191     brouard  2242: #ifdef DEBUGLINMIN
                   2243:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2244:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2245: #endif
1.224     brouard  2246: #ifdef LINMINORIGINAL
                   2247: #else
                   2248:        if(fb == fx){ /* Flat function in the direction */
                   2249:                xmin=xx;
                   2250:     *flat=1;
                   2251:        }else{
                   2252:     *flat=0;
                   2253: #endif
                   2254:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2255:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2256:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2257:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2258:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2259:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2260: #ifdef DEBUG
1.224     brouard  2261:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2262:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2263: #endif
                   2264: #ifdef LINMINORIGINAL
                   2265: #else
                   2266:                        }
1.126     brouard  2267: #endif
1.191     brouard  2268: #ifdef DEBUGLINMIN
                   2269:   printf("linmin end ");
1.202     brouard  2270:   fprintf(ficlog,"linmin end ");
1.191     brouard  2271: #endif
1.126     brouard  2272:   for (j=1;j<=n;j++) { 
1.203     brouard  2273: #ifdef LINMINORIGINAL
                   2274:     xi[j] *= xmin; 
                   2275: #else
                   2276: #ifdef DEBUGLINMIN
                   2277:     if(xxs <1.0)
                   2278:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2279: #endif
                   2280:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2281: #ifdef DEBUGLINMIN
                   2282:     if(xxs <1.0)
                   2283:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2284: #endif
                   2285: #endif
1.187     brouard  2286:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2287:   } 
1.191     brouard  2288: #ifdef DEBUGLINMIN
1.203     brouard  2289:   printf("\n");
1.191     brouard  2290:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2291:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2292:   for (j=1;j<=n;j++) { 
1.202     brouard  2293:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2294:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2295:     if(j % ncovmodel == 0){
1.191     brouard  2296:       printf("\n");
1.202     brouard  2297:       fprintf(ficlog,"\n");
                   2298:     }
1.191     brouard  2299:   }
1.203     brouard  2300: #else
1.191     brouard  2301: #endif
1.126     brouard  2302:   free_vector(xicom,1,n); 
                   2303:   free_vector(pcom,1,n); 
                   2304: } 
                   2305: 
                   2306: 
                   2307: /*************** powell ************************/
1.162     brouard  2308: /*
                   2309: Minimization of a function func of n variables. Input consists of an initial starting point
                   2310: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2311: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2312: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2313: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2314: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2315:  */
1.224     brouard  2316: #ifdef LINMINORIGINAL
                   2317: #else
                   2318:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2319:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2320: #endif
1.126     brouard  2321: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2322:            double (*func)(double [])) 
                   2323: { 
1.224     brouard  2324: #ifdef LINMINORIGINAL
                   2325:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2326:              double (*func)(double [])); 
1.224     brouard  2327: #else 
1.241     brouard  2328:  void linmin(double p[], double xi[], int n, double *fret,
                   2329:             double (*func)(double []),int *flat); 
1.224     brouard  2330: #endif
1.239     brouard  2331:  int i,ibig,j,jk,k; 
1.126     brouard  2332:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2333:   double directest;
1.126     brouard  2334:   double fp,fptt;
                   2335:   double *xits;
                   2336:   int niterf, itmp;
1.224     brouard  2337: #ifdef LINMINORIGINAL
                   2338: #else
                   2339: 
                   2340:   flatdir=ivector(1,n); 
                   2341:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2342: #endif
1.126     brouard  2343: 
                   2344:   pt=vector(1,n); 
                   2345:   ptt=vector(1,n); 
                   2346:   xit=vector(1,n); 
                   2347:   xits=vector(1,n); 
                   2348:   *fret=(*func)(p); 
                   2349:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2350:   rcurr_time = time(NULL);  
1.126     brouard  2351:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2352:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2353:     ibig=0; 
                   2354:     del=0.0; 
1.157     brouard  2355:     rlast_time=rcurr_time;
                   2356:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2357:     rcurr_time = time(NULL);  
                   2358:     curr_time = *localtime(&rcurr_time);
                   2359:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2360:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2361: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2362:     for (i=1;i<=n;i++) {
1.126     brouard  2363:       fprintf(ficrespow," %.12lf", p[i]);
                   2364:     }
1.239     brouard  2365:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2366:     printf("\n#model=  1      +     age ");
                   2367:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2368:     if(nagesqr==1){
1.241     brouard  2369:        printf("  + age*age  ");
                   2370:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2371:     }
                   2372:     for(j=1;j <=ncovmodel-2;j++){
                   2373:       if(Typevar[j]==0) {
                   2374:        printf("  +      V%d  ",Tvar[j]);
                   2375:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2376:       }else if(Typevar[j]==1) {
                   2377:        printf("  +    V%d*age ",Tvar[j]);
                   2378:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2379:       }else if(Typevar[j]==2) {
                   2380:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2381:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2382:       }
                   2383:     }
1.126     brouard  2384:     printf("\n");
1.239     brouard  2385: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2386: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2387:     fprintf(ficlog,"\n");
1.239     brouard  2388:     for(i=1,jk=1; i <=nlstate; i++){
                   2389:       for(k=1; k <=(nlstate+ndeath); k++){
                   2390:        if (k != i) {
                   2391:          printf("%d%d ",i,k);
                   2392:          fprintf(ficlog,"%d%d ",i,k);
                   2393:          for(j=1; j <=ncovmodel; j++){
                   2394:            printf("%12.7f ",p[jk]);
                   2395:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2396:            jk++; 
                   2397:          }
                   2398:          printf("\n");
                   2399:          fprintf(ficlog,"\n");
                   2400:        }
                   2401:       }
                   2402:     }
1.241     brouard  2403:     if(*iter <=3 && *iter >1){
1.157     brouard  2404:       tml = *localtime(&rcurr_time);
                   2405:       strcpy(strcurr,asctime(&tml));
                   2406:       rforecast_time=rcurr_time; 
1.126     brouard  2407:       itmp = strlen(strcurr);
                   2408:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2409:        strcurr[itmp-1]='\0';
1.162     brouard  2410:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2411:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2412:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2413:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2414:        forecast_time = *localtime(&rforecast_time);
                   2415:        strcpy(strfor,asctime(&forecast_time));
                   2416:        itmp = strlen(strfor);
                   2417:        if(strfor[itmp-1]=='\n')
                   2418:          strfor[itmp-1]='\0';
                   2419:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2420:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2421:       }
                   2422:     }
1.187     brouard  2423:     for (i=1;i<=n;i++) { /* For each direction i */
                   2424:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2425:       fptt=(*fret); 
                   2426: #ifdef DEBUG
1.203     brouard  2427:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2428:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2429: #endif
1.203     brouard  2430:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2431:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2432: #ifdef LINMINORIGINAL
1.188     brouard  2433:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2434: #else
                   2435:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2436:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2437: #endif
                   2438:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2439:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2440:                                /* because that direction will be replaced unless the gain del is small */
                   2441:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2442:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2443:                                /* with the new direction. */
                   2444:                                del=fabs(fptt-(*fret)); 
                   2445:                                ibig=i; 
1.126     brouard  2446:       } 
                   2447: #ifdef DEBUG
                   2448:       printf("%d %.12e",i,(*fret));
                   2449:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2450:       for (j=1;j<=n;j++) {
1.224     brouard  2451:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2452:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2453:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2454:       }
                   2455:       for(j=1;j<=n;j++) {
1.225     brouard  2456:                                printf(" p(%d)=%.12e",j,p[j]);
                   2457:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2458:       }
                   2459:       printf("\n");
                   2460:       fprintf(ficlog,"\n");
                   2461: #endif
1.187     brouard  2462:     } /* end loop on each direction i */
                   2463:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2464:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2465:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2466:       for(j=1;j<=n;j++) {
1.302     brouard  2467:        if(flatdir[j] >0){
                   2468:          printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2469:          fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2470:        }
                   2471:        /* printf("\n"); */
                   2472:        /* fprintf(ficlog,"\n"); */
                   2473:       }
1.243     brouard  2474:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2475:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2476:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2477:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2478:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2479:       /* decreased of more than 3.84  */
                   2480:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2481:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2482:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2483:                        
1.188     brouard  2484:       /* Starting the program with initial values given by a former maximization will simply change */
                   2485:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2486:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2487:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2488: #ifdef DEBUG
                   2489:       int k[2],l;
                   2490:       k[0]=1;
                   2491:       k[1]=-1;
                   2492:       printf("Max: %.12e",(*func)(p));
                   2493:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2494:       for (j=1;j<=n;j++) {
                   2495:        printf(" %.12e",p[j]);
                   2496:        fprintf(ficlog," %.12e",p[j]);
                   2497:       }
                   2498:       printf("\n");
                   2499:       fprintf(ficlog,"\n");
                   2500:       for(l=0;l<=1;l++) {
                   2501:        for (j=1;j<=n;j++) {
                   2502:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2503:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2504:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2505:        }
                   2506:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2507:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2508:       }
                   2509: #endif
                   2510: 
1.224     brouard  2511: #ifdef LINMINORIGINAL
                   2512: #else
                   2513:       free_ivector(flatdir,1,n); 
                   2514: #endif
1.126     brouard  2515:       free_vector(xit,1,n); 
                   2516:       free_vector(xits,1,n); 
                   2517:       free_vector(ptt,1,n); 
                   2518:       free_vector(pt,1,n); 
                   2519:       return; 
1.192     brouard  2520:     } /* enough precision */ 
1.240     brouard  2521:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2522:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2523:       ptt[j]=2.0*p[j]-pt[j]; 
                   2524:       xit[j]=p[j]-pt[j]; 
                   2525:       pt[j]=p[j]; 
                   2526:     } 
1.181     brouard  2527:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2528: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2529:                if (*iter <=4) {
1.225     brouard  2530: #else
                   2531: #endif
1.224     brouard  2532: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2533: #else
1.161     brouard  2534:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2535: #endif
1.162     brouard  2536:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2537:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2538:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2539:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2540:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2541:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2542:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2543:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2544:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2545:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2546:       /* mu² and del² are equal when f3=f1 */
                   2547:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2548:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2549:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2550:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2551: #ifdef NRCORIGINAL
                   2552:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2553: #else
                   2554:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2555:       t= t- del*SQR(fp-fptt);
1.183     brouard  2556: #endif
1.202     brouard  2557:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2558: #ifdef DEBUG
1.181     brouard  2559:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2560:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2561:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2562:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2563:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2564:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2565:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2566:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2567: #endif
1.183     brouard  2568: #ifdef POWELLORIGINAL
                   2569:       if (t < 0.0) { /* Then we use it for new direction */
                   2570: #else
1.182     brouard  2571:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2572:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2573:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2574:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2575:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2576:       } 
1.181     brouard  2577:       if (directest < 0.0) { /* Then we use it for new direction */
                   2578: #endif
1.191     brouard  2579: #ifdef DEBUGLINMIN
1.234     brouard  2580:        printf("Before linmin in direction P%d-P0\n",n);
                   2581:        for (j=1;j<=n;j++) {
                   2582:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2583:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2584:          if(j % ncovmodel == 0){
                   2585:            printf("\n");
                   2586:            fprintf(ficlog,"\n");
                   2587:          }
                   2588:        }
1.224     brouard  2589: #endif
                   2590: #ifdef LINMINORIGINAL
1.234     brouard  2591:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2592: #else
1.234     brouard  2593:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2594:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2595: #endif
1.234     brouard  2596:        
1.191     brouard  2597: #ifdef DEBUGLINMIN
1.234     brouard  2598:        for (j=1;j<=n;j++) { 
                   2599:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2600:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2601:          if(j % ncovmodel == 0){
                   2602:            printf("\n");
                   2603:            fprintf(ficlog,"\n");
                   2604:          }
                   2605:        }
1.224     brouard  2606: #endif
1.234     brouard  2607:        for (j=1;j<=n;j++) { 
                   2608:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2609:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2610:        }
1.224     brouard  2611: #ifdef LINMINORIGINAL
                   2612: #else
1.234     brouard  2613:        for (j=1, flatd=0;j<=n;j++) {
                   2614:          if(flatdir[j]>0)
                   2615:            flatd++;
                   2616:        }
                   2617:        if(flatd >0){
1.255     brouard  2618:          printf("%d flat directions: ",flatd);
                   2619:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2620:          for (j=1;j<=n;j++) { 
                   2621:            if(flatdir[j]>0){
                   2622:              printf("%d ",j);
                   2623:              fprintf(ficlog,"%d ",j);
                   2624:            }
                   2625:          }
                   2626:          printf("\n");
                   2627:          fprintf(ficlog,"\n");
                   2628:        }
1.191     brouard  2629: #endif
1.234     brouard  2630:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2631:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2632:        
1.126     brouard  2633: #ifdef DEBUG
1.234     brouard  2634:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2635:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2636:        for(j=1;j<=n;j++){
                   2637:          printf(" %lf",xit[j]);
                   2638:          fprintf(ficlog," %lf",xit[j]);
                   2639:        }
                   2640:        printf("\n");
                   2641:        fprintf(ficlog,"\n");
1.126     brouard  2642: #endif
1.192     brouard  2643:       } /* end of t or directest negative */
1.224     brouard  2644: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2645: #else
1.234     brouard  2646:       } /* end if (fptt < fp)  */
1.192     brouard  2647: #endif
1.225     brouard  2648: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2649:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2650: #else
1.224     brouard  2651: #endif
1.234     brouard  2652:                } /* loop iteration */ 
1.126     brouard  2653: } 
1.234     brouard  2654:   
1.126     brouard  2655: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2656:   
1.235     brouard  2657:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2658:   {
1.279     brouard  2659:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2660:      *   (and selected quantitative values in nres)
                   2661:      *  by left multiplying the unit
                   2662:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2663:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2664:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2665:      * or prevalence in state 1, prevalence in state 2, 0
                   2666:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2667:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2668:      * Output is prlim.
                   2669:      * Initial matrix pimij 
                   2670:      */
1.206     brouard  2671:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2672:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2673:   /*  0,                   0                  , 1} */
                   2674:   /*
                   2675:    * and after some iteration: */
                   2676:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2677:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2678:   /*  0,                   0                  , 1} */
                   2679:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2680:   /* {0.51571254859325999, 0.4842874514067399, */
                   2681:   /*  0.51326036147820708, 0.48673963852179264} */
                   2682:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2683:     
1.126     brouard  2684:   int i, ii,j,k;
1.209     brouard  2685:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2686:   /* double **matprod2(); */ /* test */
1.218     brouard  2687:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2688:   double **newm;
1.209     brouard  2689:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2690:   int ncvloop=0;
1.288     brouard  2691:   int first=0;
1.169     brouard  2692:   
1.209     brouard  2693:   min=vector(1,nlstate);
                   2694:   max=vector(1,nlstate);
                   2695:   meandiff=vector(1,nlstate);
                   2696: 
1.218     brouard  2697:        /* Starting with matrix unity */
1.126     brouard  2698:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2699:     for (j=1;j<=nlstate+ndeath;j++){
                   2700:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2701:     }
1.169     brouard  2702:   
                   2703:   cov[1]=1.;
                   2704:   
                   2705:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2706:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2707:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2708:     ncvloop++;
1.126     brouard  2709:     newm=savm;
                   2710:     /* Covariates have to be included here again */
1.138     brouard  2711:     cov[2]=agefin;
1.187     brouard  2712:     if(nagesqr==1)
                   2713:       cov[3]= agefin*agefin;;
1.234     brouard  2714:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2715:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2716:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2717:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2718:     }
                   2719:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2720:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2721:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2722:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2723:     }
1.237     brouard  2724:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2725:       if(Dummy[Tvar[Tage[k]]]){
                   2726:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2727:       } else{
1.235     brouard  2728:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2729:       }
1.235     brouard  2730:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2731:     }
1.237     brouard  2732:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2733:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2734:       if(Dummy[Tvard[k][1]==0]){
                   2735:        if(Dummy[Tvard[k][2]==0]){
                   2736:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2737:        }else{
                   2738:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2739:        }
                   2740:       }else{
                   2741:        if(Dummy[Tvard[k][2]==0]){
                   2742:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2743:        }else{
                   2744:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2745:        }
                   2746:       }
1.234     brouard  2747:     }
1.138     brouard  2748:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2749:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2750:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2751:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2752:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2753:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2754:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2755:     
1.126     brouard  2756:     savm=oldm;
                   2757:     oldm=newm;
1.209     brouard  2758: 
                   2759:     for(j=1; j<=nlstate; j++){
                   2760:       max[j]=0.;
                   2761:       min[j]=1.;
                   2762:     }
                   2763:     for(i=1;i<=nlstate;i++){
                   2764:       sumnew=0;
                   2765:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2766:       for(j=1; j<=nlstate; j++){ 
                   2767:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2768:        max[j]=FMAX(max[j],prlim[i][j]);
                   2769:        min[j]=FMIN(min[j],prlim[i][j]);
                   2770:       }
                   2771:     }
                   2772: 
1.126     brouard  2773:     maxmax=0.;
1.209     brouard  2774:     for(j=1; j<=nlstate; j++){
                   2775:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2776:       maxmax=FMAX(maxmax,meandiff[j]);
                   2777:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2778:     } /* j loop */
1.203     brouard  2779:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2780:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2781:     if(maxmax < ftolpl){
1.209     brouard  2782:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2783:       free_vector(min,1,nlstate);
                   2784:       free_vector(max,1,nlstate);
                   2785:       free_vector(meandiff,1,nlstate);
1.126     brouard  2786:       return prlim;
                   2787:     }
1.288     brouard  2788:   } /* agefin loop */
1.208     brouard  2789:     /* After some age loop it doesn't converge */
1.288     brouard  2790:   if(!first){
                   2791:     first=1;
                   2792:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2793:   }
                   2794:   fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2795: 
1.209     brouard  2796:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2797:   free_vector(min,1,nlstate);
                   2798:   free_vector(max,1,nlstate);
                   2799:   free_vector(meandiff,1,nlstate);
1.208     brouard  2800:   
1.169     brouard  2801:   return prlim; /* should not reach here */
1.126     brouard  2802: }
                   2803: 
1.217     brouard  2804: 
                   2805:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2806: 
1.218     brouard  2807:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2808:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2809:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2810: {
1.264     brouard  2811:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2812:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2813:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2814:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2815:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2816:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2817:   /* Initial matrix pimij */
                   2818:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2819:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2820:   /*  0,                   0                  , 1} */
                   2821:   /*
                   2822:    * and after some iteration: */
                   2823:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2824:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2825:   /*  0,                   0                  , 1} */
                   2826:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2827:   /* {0.51571254859325999, 0.4842874514067399, */
                   2828:   /*  0.51326036147820708, 0.48673963852179264} */
                   2829:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2830: 
                   2831:   int i, ii,j,k;
1.247     brouard  2832:   int first=0;
1.217     brouard  2833:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2834:   /* double **matprod2(); */ /* test */
                   2835:   double **out, cov[NCOVMAX+1], **bmij();
                   2836:   double **newm;
1.218     brouard  2837:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2838:   double        **oldm, **savm;  /* for use */
                   2839: 
1.217     brouard  2840:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2841:   int ncvloop=0;
                   2842:   
                   2843:   min=vector(1,nlstate);
                   2844:   max=vector(1,nlstate);
                   2845:   meandiff=vector(1,nlstate);
                   2846: 
1.266     brouard  2847:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2848:   oldm=oldms; savm=savms;
                   2849:   
                   2850:   /* Starting with matrix unity */
                   2851:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2852:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2853:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2854:     }
                   2855:   
                   2856:   cov[1]=1.;
                   2857:   
                   2858:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2859:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2860:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2861:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2862:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2863:     ncvloop++;
1.218     brouard  2864:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2865:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2866:     /* Covariates have to be included here again */
                   2867:     cov[2]=agefin;
                   2868:     if(nagesqr==1)
                   2869:       cov[3]= agefin*agefin;;
1.242     brouard  2870:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2871:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2872:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2873:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2874:     }
                   2875:     /* for (k=1; k<=cptcovn;k++) { */
                   2876:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2877:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2878:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2879:     /* } */
                   2880:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2881:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2882:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2883:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2884:     }
                   2885:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2886:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2887:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2888:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2889:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2890:       if(Dummy[Tvar[Tage[k]]]){
                   2891:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2892:       } else{
                   2893:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2894:       }
                   2895:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2896:     }
                   2897:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2898:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2899:       if(Dummy[Tvard[k][1]==0]){
                   2900:        if(Dummy[Tvard[k][2]==0]){
                   2901:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2902:        }else{
                   2903:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2904:        }
                   2905:       }else{
                   2906:        if(Dummy[Tvard[k][2]==0]){
                   2907:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2908:        }else{
                   2909:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2910:        }
                   2911:       }
1.217     brouard  2912:     }
                   2913:     
                   2914:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2915:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2916:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2917:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2918:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2919:                /* ij should be linked to the correct index of cov */
                   2920:                /* age and covariate values ij are in 'cov', but we need to pass
                   2921:                 * ij for the observed prevalence at age and status and covariate
                   2922:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2923:                 */
                   2924:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2925:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2926:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2927:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2928:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2929:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2930:     /*         printf("%d newm= ",i); */
                   2931:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2932:     /*           printf("%f ",newm[i][j]); */
                   2933:     /*         } */
                   2934:     /*         printf("oldm * "); */
                   2935:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2936:     /*           printf("%f ",oldm[i][j]); */
                   2937:     /*         } */
1.268     brouard  2938:     /*         printf(" bmmij "); */
1.266     brouard  2939:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2940:     /*           printf("%f ",pmmij[i][j]); */
                   2941:     /*         } */
                   2942:     /*         printf("\n"); */
                   2943:     /*   } */
                   2944:     /* } */
1.217     brouard  2945:     savm=oldm;
                   2946:     oldm=newm;
1.266     brouard  2947: 
1.217     brouard  2948:     for(j=1; j<=nlstate; j++){
                   2949:       max[j]=0.;
                   2950:       min[j]=1.;
                   2951:     }
                   2952:     for(j=1; j<=nlstate; j++){ 
                   2953:       for(i=1;i<=nlstate;i++){
1.234     brouard  2954:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2955:        bprlim[i][j]= newm[i][j];
                   2956:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2957:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2958:       }
                   2959:     }
1.218     brouard  2960:                
1.217     brouard  2961:     maxmax=0.;
                   2962:     for(i=1; i<=nlstate; i++){
                   2963:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2964:       maxmax=FMAX(maxmax,meandiff[i]);
                   2965:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2966:     } /* i loop */
1.217     brouard  2967:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2968:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2969:     if(maxmax < ftolpl){
1.220     brouard  2970:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2971:       free_vector(min,1,nlstate);
                   2972:       free_vector(max,1,nlstate);
                   2973:       free_vector(meandiff,1,nlstate);
                   2974:       return bprlim;
                   2975:     }
1.288     brouard  2976:   } /* agefin loop */
1.217     brouard  2977:     /* After some age loop it doesn't converge */
1.288     brouard  2978:   if(!first){
1.247     brouard  2979:     first=1;
                   2980:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2981: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2982:   }
                   2983:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2984: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2985:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2986:   free_vector(min,1,nlstate);
                   2987:   free_vector(max,1,nlstate);
                   2988:   free_vector(meandiff,1,nlstate);
                   2989:   
                   2990:   return bprlim; /* should not reach here */
                   2991: }
                   2992: 
1.126     brouard  2993: /*************** transition probabilities ***************/ 
                   2994: 
                   2995: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2996: {
1.138     brouard  2997:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2998:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2999:      model to the ncovmodel covariates (including constant and age).
                   3000:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3001:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3002:      ncth covariate in the global vector x is given by the formula:
                   3003:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3004:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3005:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3006:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  3007:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  3008:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  3009:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  3010:   */
                   3011:   double s1, lnpijopii;
1.126     brouard  3012:   /*double t34;*/
1.164     brouard  3013:   int i,j, nc, ii, jj;
1.126     brouard  3014: 
1.223     brouard  3015:   for(i=1; i<= nlstate; i++){
                   3016:     for(j=1; j<i;j++){
                   3017:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3018:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3019:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3020:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3021:       }
                   3022:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3023:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3024:     }
                   3025:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3026:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3027:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3028:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3029:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3030:       }
                   3031:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3032:     }
                   3033:   }
1.218     brouard  3034:   
1.223     brouard  3035:   for(i=1; i<= nlstate; i++){
                   3036:     s1=0;
                   3037:     for(j=1; j<i; j++){
                   3038:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3039:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3040:     }
                   3041:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3042:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3043:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3044:     }
                   3045:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3046:     ps[i][i]=1./(s1+1.);
                   3047:     /* Computing other pijs */
                   3048:     for(j=1; j<i; j++)
                   3049:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3050:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3051:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3052:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3053:   } /* end i */
1.218     brouard  3054:   
1.223     brouard  3055:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3056:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3057:       ps[ii][jj]=0;
                   3058:       ps[ii][ii]=1;
                   3059:     }
                   3060:   }
1.294     brouard  3061: 
                   3062: 
1.223     brouard  3063:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3064:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3065:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3066:   /*   } */
                   3067:   /*   printf("\n "); */
                   3068:   /* } */
                   3069:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3070:   /*
                   3071:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  3072:                goto end;*/
1.266     brouard  3073:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  3074: }
                   3075: 
1.218     brouard  3076: /*************** backward transition probabilities ***************/ 
                   3077: 
                   3078:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3079: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3080:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   3081: {
1.302     brouard  3082:   /* Computes the backward probability at age agefin, cov[2], and covariate combination 'ij'. In fact cov is already filled and x too.
1.266     brouard  3083:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  3084:    */
1.218     brouard  3085:   int i, ii, j,k;
1.222     brouard  3086:   
                   3087:   double **out, **pmij();
                   3088:   double sumnew=0.;
1.218     brouard  3089:   double agefin;
1.292     brouard  3090:   double k3=0.; /* constant of the w_x diagonal matrix (in order for B to sum to 1 even for death state) */
1.222     brouard  3091:   double **dnewm, **dsavm, **doldm;
                   3092:   double **bbmij;
                   3093:   
1.218     brouard  3094:   doldm=ddoldms; /* global pointers */
1.222     brouard  3095:   dnewm=ddnewms;
                   3096:   dsavm=ddsavms;
                   3097:   
                   3098:   agefin=cov[2];
1.268     brouard  3099:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3100:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3101:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3102:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3103: 
                   3104:   /* P_x */
1.266     brouard  3105:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  3106:   /* outputs pmmij which is a stochastic matrix in row */
                   3107: 
                   3108:   /* Diag(w_x) */
1.292     brouard  3109:   /* Rescaling the cross-sectional prevalence: Problem with prevacurrent which can be zero */
1.268     brouard  3110:   sumnew=0.;
1.269     brouard  3111:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3112:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.297     brouard  3113:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]); */
1.268     brouard  3114:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3115:   }
                   3116:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3117:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3118:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3119:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3120:     }
                   3121:   }else{
                   3122:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3123:       for (j=1;j<=nlstate+ndeath;j++)
                   3124:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3125:     }
                   3126:     /* if(sumnew <0.9){ */
                   3127:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3128:     /* } */
                   3129:   }
                   3130:   k3=0.0;  /* We put the last diagonal to 0 */
                   3131:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3132:       doldm[ii][ii]= k3;
                   3133:   }
                   3134:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3135:   
1.292     brouard  3136:   /* Left product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm): diag[(w_i)*Px */
                   3137:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* was a Bug Valgrind */
1.268     brouard  3138: 
1.292     brouard  3139:   /* Diag(Sum_i w^i_x p^ij_x, should be the prevalence at age x+stepm */
1.268     brouard  3140:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3141:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3142:     sumnew=0.;
1.222     brouard  3143:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3144:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3145:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3146:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3147:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3148:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3149:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3150:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3151:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3152:        /* }else */
1.268     brouard  3153:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3154:     } /*End ii */
                   3155:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3156: 
1.292     brouard  3157:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* was a Bug Valgrind */
1.268     brouard  3158:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3159:   /* end bmij */
1.266     brouard  3160:   return ps; /*pointer is unchanged */
1.218     brouard  3161: }
1.217     brouard  3162: /*************** transition probabilities ***************/ 
                   3163: 
1.218     brouard  3164: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3165: {
                   3166:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3167:      computes the probability to be observed in state j being in state i by appying the
                   3168:      model to the ncovmodel covariates (including constant and age).
                   3169:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3170:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3171:      ncth covariate in the global vector x is given by the formula:
                   3172:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3173:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3174:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3175:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3176:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3177:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3178:   */
                   3179:   double s1, lnpijopii;
                   3180:   /*double t34;*/
                   3181:   int i,j, nc, ii, jj;
                   3182: 
1.234     brouard  3183:   for(i=1; i<= nlstate; i++){
                   3184:     for(j=1; j<i;j++){
                   3185:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3186:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3187:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3188:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3189:       }
                   3190:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3191:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3192:     }
                   3193:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3194:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3195:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3196:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3197:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3198:       }
                   3199:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3200:     }
                   3201:   }
                   3202:   
                   3203:   for(i=1; i<= nlstate; i++){
                   3204:     s1=0;
                   3205:     for(j=1; j<i; j++){
                   3206:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3207:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3208:     }
                   3209:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3210:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3211:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3212:     }
                   3213:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3214:     ps[i][i]=1./(s1+1.);
                   3215:     /* Computing other pijs */
                   3216:     for(j=1; j<i; j++)
                   3217:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3218:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3219:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3220:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3221:   } /* end i */
                   3222:   
                   3223:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3224:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3225:       ps[ii][jj]=0;
                   3226:       ps[ii][ii]=1;
                   3227:     }
                   3228:   }
1.296     brouard  3229:   /* Added for prevbcast */ /* Transposed matrix too */
1.234     brouard  3230:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3231:     s1=0.;
                   3232:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3233:       s1+=ps[ii][jj];
                   3234:     }
                   3235:     for(ii=1; ii<= nlstate; ii++){
                   3236:       ps[ii][jj]=ps[ii][jj]/s1;
                   3237:     }
                   3238:   }
                   3239:   /* Transposition */
                   3240:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3241:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3242:       s1=ps[ii][jj];
                   3243:       ps[ii][jj]=ps[jj][ii];
                   3244:       ps[jj][ii]=s1;
                   3245:     }
                   3246:   }
                   3247:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3248:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3249:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3250:   /*   } */
                   3251:   /*   printf("\n "); */
                   3252:   /* } */
                   3253:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3254:   /*
                   3255:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3256:     goto end;*/
                   3257:   return ps;
1.217     brouard  3258: }
                   3259: 
                   3260: 
1.126     brouard  3261: /**************** Product of 2 matrices ******************/
                   3262: 
1.145     brouard  3263: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3264: {
                   3265:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3266:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3267:   /* in, b, out are matrice of pointers which should have been initialized 
                   3268:      before: only the contents of out is modified. The function returns
                   3269:      a pointer to pointers identical to out */
1.145     brouard  3270:   int i, j, k;
1.126     brouard  3271:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3272:     for(k=ncolol; k<=ncoloh; k++){
                   3273:       out[i][k]=0.;
                   3274:       for(j=ncl; j<=nch; j++)
                   3275:        out[i][k] +=in[i][j]*b[j][k];
                   3276:     }
1.126     brouard  3277:   return out;
                   3278: }
                   3279: 
                   3280: 
                   3281: /************* Higher Matrix Product ***************/
                   3282: 
1.235     brouard  3283: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3284: {
1.218     brouard  3285:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3286:      'nhstepm*hstepm*stepm' months (i.e. until
                   3287:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3288:      nhstepm*hstepm matrices. 
                   3289:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3290:      (typically every 2 years instead of every month which is too big 
                   3291:      for the memory).
                   3292:      Model is determined by parameters x and covariates have to be 
                   3293:      included manually here. 
                   3294: 
                   3295:      */
                   3296: 
                   3297:   int i, j, d, h, k;
1.131     brouard  3298:   double **out, cov[NCOVMAX+1];
1.126     brouard  3299:   double **newm;
1.187     brouard  3300:   double agexact;
1.214     brouard  3301:   double agebegin, ageend;
1.126     brouard  3302: 
                   3303:   /* Hstepm could be zero and should return the unit matrix */
                   3304:   for (i=1;i<=nlstate+ndeath;i++)
                   3305:     for (j=1;j<=nlstate+ndeath;j++){
                   3306:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3307:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3308:     }
                   3309:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3310:   for(h=1; h <=nhstepm; h++){
                   3311:     for(d=1; d <=hstepm; d++){
                   3312:       newm=savm;
                   3313:       /* Covariates have to be included here again */
                   3314:       cov[1]=1.;
1.214     brouard  3315:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3316:       cov[2]=agexact;
                   3317:       if(nagesqr==1)
1.227     brouard  3318:        cov[3]= agexact*agexact;
1.235     brouard  3319:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3320:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3321:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3322:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3323:       }
                   3324:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3325:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3326:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3327:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3328:       }
                   3329:       for (k=1; k<=cptcovage;k++){
                   3330:        if(Dummy[Tvar[Tage[k]]]){
                   3331:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3332:        } else{
                   3333:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3334:        }
                   3335:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3336:       }
                   3337:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3338:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3339:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3340:       }
                   3341:       /* for (k=1; k<=cptcovn;k++)  */
                   3342:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3343:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3344:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3345:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3346:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3347:       
                   3348:       
1.126     brouard  3349:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3350:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3351:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3352:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3353:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3354:       /* if((int)age == 70){ */
                   3355:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3356:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3357:       /*         printf("%d pmmij ",i); */
                   3358:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3359:       /*           printf("%f ",pmmij[i][j]); */
                   3360:       /*         } */
                   3361:       /*         printf(" oldm "); */
                   3362:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3363:       /*           printf("%f ",oldm[i][j]); */
                   3364:       /*         } */
                   3365:       /*         printf("\n"); */
                   3366:       /*       } */
                   3367:       /* } */
1.126     brouard  3368:       savm=oldm;
                   3369:       oldm=newm;
                   3370:     }
                   3371:     for(i=1; i<=nlstate+ndeath; i++)
                   3372:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3373:        po[i][j][h]=newm[i][j];
                   3374:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3375:       }
1.128     brouard  3376:     /*printf("h=%d ",h);*/
1.126     brouard  3377:   } /* end h */
1.267     brouard  3378:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3379:   return po;
                   3380: }
                   3381: 
1.217     brouard  3382: /************* Higher Back Matrix Product ***************/
1.218     brouard  3383: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3384: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3385: {
1.266     brouard  3386:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3387:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3388:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3389:      nhstepm*hstepm matrices.
                   3390:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3391:      (typically every 2 years instead of every month which is too big
1.217     brouard  3392:      for the memory).
1.218     brouard  3393:      Model is determined by parameters x and covariates have to be
1.266     brouard  3394:      included manually here. Then we use a call to bmij(x and cov)
                   3395:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3396:   */
1.217     brouard  3397: 
                   3398:   int i, j, d, h, k;
1.266     brouard  3399:   double **out, cov[NCOVMAX+1], **bmij();
                   3400:   double **newm, ***newmm;
1.217     brouard  3401:   double agexact;
                   3402:   double agebegin, ageend;
1.222     brouard  3403:   double **oldm, **savm;
1.217     brouard  3404: 
1.266     brouard  3405:   newmm=po; /* To be saved */
                   3406:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3407:   /* Hstepm could be zero and should return the unit matrix */
                   3408:   for (i=1;i<=nlstate+ndeath;i++)
                   3409:     for (j=1;j<=nlstate+ndeath;j++){
                   3410:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3411:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3412:     }
                   3413:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3414:   for(h=1; h <=nhstepm; h++){
                   3415:     for(d=1; d <=hstepm; d++){
                   3416:       newm=savm;
                   3417:       /* Covariates have to be included here again */
                   3418:       cov[1]=1.;
1.271     brouard  3419:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3420:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3421:       cov[2]=agexact;
                   3422:       if(nagesqr==1)
1.222     brouard  3423:        cov[3]= agexact*agexact;
1.266     brouard  3424:       for (k=1; k<=cptcovn;k++){
                   3425:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3426:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3427:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3428:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3429:       }
1.267     brouard  3430:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3431:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3432:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3433:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3434:       }
                   3435:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3436:        if(Dummy[Tvar[Tage[k]]]){
                   3437:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3438:        } else{
                   3439:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3440:        }
                   3441:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3442:       }
                   3443:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3444:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3445:       }                        
1.217     brouard  3446:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3447:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3448: 
1.218     brouard  3449:       /* Careful transposed matrix */
1.266     brouard  3450:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3451:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3452:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3453:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3454:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3455:       /* if((int)age == 70){ */
                   3456:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3457:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3458:       /*         printf("%d pmmij ",i); */
                   3459:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3460:       /*           printf("%f ",pmmij[i][j]); */
                   3461:       /*         } */
                   3462:       /*         printf(" oldm "); */
                   3463:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3464:       /*           printf("%f ",oldm[i][j]); */
                   3465:       /*         } */
                   3466:       /*         printf("\n"); */
                   3467:       /*       } */
                   3468:       /* } */
                   3469:       savm=oldm;
                   3470:       oldm=newm;
                   3471:     }
                   3472:     for(i=1; i<=nlstate+ndeath; i++)
                   3473:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3474:        po[i][j][h]=newm[i][j];
1.268     brouard  3475:        /* if(h==nhstepm) */
                   3476:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3477:       }
1.268     brouard  3478:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3479:   } /* end h */
1.268     brouard  3480:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3481:   return po;
                   3482: }
                   3483: 
                   3484: 
1.162     brouard  3485: #ifdef NLOPT
                   3486:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3487:   double fret;
                   3488:   double *xt;
                   3489:   int j;
                   3490:   myfunc_data *d2 = (myfunc_data *) pd;
                   3491: /* xt = (p1-1); */
                   3492:   xt=vector(1,n); 
                   3493:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3494: 
                   3495:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3496:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3497:   printf("Function = %.12lf ",fret);
                   3498:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3499:   printf("\n");
                   3500:  free_vector(xt,1,n);
                   3501:   return fret;
                   3502: }
                   3503: #endif
1.126     brouard  3504: 
                   3505: /*************** log-likelihood *************/
                   3506: double func( double *x)
                   3507: {
1.226     brouard  3508:   int i, ii, j, k, mi, d, kk;
                   3509:   int ioffset=0;
                   3510:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3511:   double **out;
                   3512:   double lli; /* Individual log likelihood */
                   3513:   int s1, s2;
1.228     brouard  3514:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3515:   double bbh, survp;
                   3516:   long ipmx;
                   3517:   double agexact;
                   3518:   /*extern weight */
                   3519:   /* We are differentiating ll according to initial status */
                   3520:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3521:   /*for(i=1;i<imx;i++) 
                   3522:     printf(" %d\n",s[4][i]);
                   3523:   */
1.162     brouard  3524: 
1.226     brouard  3525:   ++countcallfunc;
1.162     brouard  3526: 
1.226     brouard  3527:   cov[1]=1.;
1.126     brouard  3528: 
1.226     brouard  3529:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3530:   ioffset=0;
1.226     brouard  3531:   if(mle==1){
                   3532:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3533:       /* Computes the values of the ncovmodel covariates of the model
                   3534:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3535:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3536:         to be observed in j being in i according to the model.
                   3537:       */
1.243     brouard  3538:       ioffset=2+nagesqr ;
1.233     brouard  3539:    /* Fixed */
1.234     brouard  3540:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3541:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3542:       }
1.226     brouard  3543:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3544:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3545:         has been calculated etc */
                   3546:       /* For an individual i, wav[i] gives the number of effective waves */
                   3547:       /* We compute the contribution to Likelihood of each effective transition
                   3548:         mw[mi][i] is real wave of the mi th effectve wave */
                   3549:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3550:         s2=s[mw[mi+1][i]][i];
                   3551:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3552:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3553:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3554:       */
                   3555:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3556:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3557:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3558:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3559:        }
                   3560:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3561:          for (j=1;j<=nlstate+ndeath;j++){
                   3562:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3563:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3564:          }
                   3565:        for(d=0; d<dh[mi][i]; d++){
                   3566:          newm=savm;
                   3567:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3568:          cov[2]=agexact;
                   3569:          if(nagesqr==1)
                   3570:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3571:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3572:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3573:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3574:          else
                   3575:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3576:          }
                   3577:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3578:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3579:          savm=oldm;
                   3580:          oldm=newm;
                   3581:        } /* end mult */
                   3582:        
                   3583:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3584:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3585:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3586:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3587:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3588:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3589:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3590:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3591:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3592:                                 * -stepm/2 to stepm/2 .
                   3593:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3594:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3595:                                 */
1.234     brouard  3596:        s1=s[mw[mi][i]][i];
                   3597:        s2=s[mw[mi+1][i]][i];
                   3598:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3599:        /* bias bh is positive if real duration
                   3600:         * is higher than the multiple of stepm and negative otherwise.
                   3601:         */
                   3602:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3603:        if( s2 > nlstate){ 
                   3604:          /* i.e. if s2 is a death state and if the date of death is known 
                   3605:             then the contribution to the likelihood is the probability to 
                   3606:             die between last step unit time and current  step unit time, 
                   3607:             which is also equal to probability to die before dh 
                   3608:             minus probability to die before dh-stepm . 
                   3609:             In version up to 0.92 likelihood was computed
                   3610:             as if date of death was unknown. Death was treated as any other
                   3611:             health state: the date of the interview describes the actual state
                   3612:             and not the date of a change in health state. The former idea was
                   3613:             to consider that at each interview the state was recorded
                   3614:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3615:             introduced the exact date of death then we should have modified
                   3616:             the contribution of an exact death to the likelihood. This new
                   3617:             contribution is smaller and very dependent of the step unit
                   3618:             stepm. It is no more the probability to die between last interview
                   3619:             and month of death but the probability to survive from last
                   3620:             interview up to one month before death multiplied by the
                   3621:             probability to die within a month. Thanks to Chris
                   3622:             Jackson for correcting this bug.  Former versions increased
                   3623:             mortality artificially. The bad side is that we add another loop
                   3624:             which slows down the processing. The difference can be up to 10%
                   3625:             lower mortality.
                   3626:          */
                   3627:          /* If, at the beginning of the maximization mostly, the
                   3628:             cumulative probability or probability to be dead is
                   3629:             constant (ie = 1) over time d, the difference is equal to
                   3630:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3631:             s1 at precedent wave, to be dead a month before current
                   3632:             wave is equal to probability, being at state s1 at
                   3633:             precedent wave, to be dead at mont of the current
                   3634:             wave. Then the observed probability (that this person died)
                   3635:             is null according to current estimated parameter. In fact,
                   3636:             it should be very low but not zero otherwise the log go to
                   3637:             infinity.
                   3638:          */
1.183     brouard  3639: /* #ifdef INFINITYORIGINAL */
                   3640: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3641: /* #else */
                   3642: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3643: /*         lli=log(mytinydouble); */
                   3644: /*       else */
                   3645: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3646: /* #endif */
1.226     brouard  3647:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3648:          
1.226     brouard  3649:        } else if  ( s2==-1 ) { /* alive */
                   3650:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3651:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3652:          /*survp += out[s1][j]; */
                   3653:          lli= log(survp);
                   3654:        }
                   3655:        else if  (s2==-4) { 
                   3656:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3657:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3658:          lli= log(survp); 
                   3659:        } 
                   3660:        else if  (s2==-5) { 
                   3661:          for (j=1,survp=0. ; j<=2; j++)  
                   3662:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3663:          lli= log(survp); 
                   3664:        } 
                   3665:        else{
                   3666:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3667:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3668:        } 
                   3669:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3670:        /*if(lli ==000.0)*/
                   3671:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3672:        ipmx +=1;
                   3673:        sw += weight[i];
                   3674:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3675:        /* if (lli < log(mytinydouble)){ */
                   3676:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3677:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3678:        /* } */
                   3679:       } /* end of wave */
                   3680:     } /* end of individual */
                   3681:   }  else if(mle==2){
                   3682:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3683:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3684:       for(mi=1; mi<= wav[i]-1; mi++){
                   3685:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3686:          for (j=1;j<=nlstate+ndeath;j++){
                   3687:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3688:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3689:          }
                   3690:        for(d=0; d<=dh[mi][i]; d++){
                   3691:          newm=savm;
                   3692:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3693:          cov[2]=agexact;
                   3694:          if(nagesqr==1)
                   3695:            cov[3]= agexact*agexact;
                   3696:          for (kk=1; kk<=cptcovage;kk++) {
                   3697:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3698:          }
                   3699:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3700:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3701:          savm=oldm;
                   3702:          oldm=newm;
                   3703:        } /* end mult */
                   3704:       
                   3705:        s1=s[mw[mi][i]][i];
                   3706:        s2=s[mw[mi+1][i]][i];
                   3707:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3708:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3709:        ipmx +=1;
                   3710:        sw += weight[i];
                   3711:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3712:       } /* end of wave */
                   3713:     } /* end of individual */
                   3714:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3715:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3716:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3717:       for(mi=1; mi<= wav[i]-1; mi++){
                   3718:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3719:          for (j=1;j<=nlstate+ndeath;j++){
                   3720:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3721:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3722:          }
                   3723:        for(d=0; d<dh[mi][i]; d++){
                   3724:          newm=savm;
                   3725:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3726:          cov[2]=agexact;
                   3727:          if(nagesqr==1)
                   3728:            cov[3]= agexact*agexact;
                   3729:          for (kk=1; kk<=cptcovage;kk++) {
                   3730:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3731:          }
                   3732:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3733:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3734:          savm=oldm;
                   3735:          oldm=newm;
                   3736:        } /* end mult */
                   3737:       
                   3738:        s1=s[mw[mi][i]][i];
                   3739:        s2=s[mw[mi+1][i]][i];
                   3740:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3741:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3742:        ipmx +=1;
                   3743:        sw += weight[i];
                   3744:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3745:       } /* end of wave */
                   3746:     } /* end of individual */
                   3747:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3748:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3749:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3750:       for(mi=1; mi<= wav[i]-1; mi++){
                   3751:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3752:          for (j=1;j<=nlstate+ndeath;j++){
                   3753:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3754:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3755:          }
                   3756:        for(d=0; d<dh[mi][i]; d++){
                   3757:          newm=savm;
                   3758:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3759:          cov[2]=agexact;
                   3760:          if(nagesqr==1)
                   3761:            cov[3]= agexact*agexact;
                   3762:          for (kk=1; kk<=cptcovage;kk++) {
                   3763:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3764:          }
1.126     brouard  3765:        
1.226     brouard  3766:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3767:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3768:          savm=oldm;
                   3769:          oldm=newm;
                   3770:        } /* end mult */
                   3771:       
                   3772:        s1=s[mw[mi][i]][i];
                   3773:        s2=s[mw[mi+1][i]][i];
                   3774:        if( s2 > nlstate){ 
                   3775:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3776:        } else if  ( s2==-1 ) { /* alive */
                   3777:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3778:            survp += out[s1][j];
                   3779:          lli= log(survp);
                   3780:        }else{
                   3781:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3782:        }
                   3783:        ipmx +=1;
                   3784:        sw += weight[i];
                   3785:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3786: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3787:       } /* end of wave */
                   3788:     } /* end of individual */
                   3789:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3790:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3791:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3792:       for(mi=1; mi<= wav[i]-1; mi++){
                   3793:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3794:          for (j=1;j<=nlstate+ndeath;j++){
                   3795:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3796:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3797:          }
                   3798:        for(d=0; d<dh[mi][i]; d++){
                   3799:          newm=savm;
                   3800:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3801:          cov[2]=agexact;
                   3802:          if(nagesqr==1)
                   3803:            cov[3]= agexact*agexact;
                   3804:          for (kk=1; kk<=cptcovage;kk++) {
                   3805:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3806:          }
1.126     brouard  3807:        
1.226     brouard  3808:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3809:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3810:          savm=oldm;
                   3811:          oldm=newm;
                   3812:        } /* end mult */
                   3813:       
                   3814:        s1=s[mw[mi][i]][i];
                   3815:        s2=s[mw[mi+1][i]][i];
                   3816:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3817:        ipmx +=1;
                   3818:        sw += weight[i];
                   3819:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3820:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3821:       } /* end of wave */
                   3822:     } /* end of individual */
                   3823:   } /* End of if */
                   3824:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3825:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3826:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3827:   return -l;
1.126     brouard  3828: }
                   3829: 
                   3830: /*************** log-likelihood *************/
                   3831: double funcone( double *x)
                   3832: {
1.228     brouard  3833:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3834:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3835:   int ioffset=0;
1.131     brouard  3836:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3837:   double **out;
                   3838:   double lli; /* Individual log likelihood */
                   3839:   double llt;
                   3840:   int s1, s2;
1.228     brouard  3841:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3842: 
1.126     brouard  3843:   double bbh, survp;
1.187     brouard  3844:   double agexact;
1.214     brouard  3845:   double agebegin, ageend;
1.126     brouard  3846:   /*extern weight */
                   3847:   /* We are differentiating ll according to initial status */
                   3848:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3849:   /*for(i=1;i<imx;i++) 
                   3850:     printf(" %d\n",s[4][i]);
                   3851:   */
                   3852:   cov[1]=1.;
                   3853: 
                   3854:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3855:   ioffset=0;
                   3856:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3857:     /* ioffset=2+nagesqr+cptcovage; */
                   3858:     ioffset=2+nagesqr;
1.232     brouard  3859:     /* Fixed */
1.224     brouard  3860:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3861:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
1.311     brouard  3862:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products *//* Missing values are set to -1 but should be dropped */
1.232     brouard  3863:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3864: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3865: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3866: /*    cov[2+6]=covar[2][i]; V2  */
                   3867: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3868: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3869: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3870: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3871: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3872: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3873:     }
1.232     brouard  3874:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3875:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3876:     /* } */
1.231     brouard  3877:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3878:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3879:     /* } */
1.225     brouard  3880:     
1.233     brouard  3881: 
                   3882:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3883:     /* Wave varying (but not age varying) */
                   3884:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3885:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3886:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3887:       }
1.232     brouard  3888:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3889:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3890:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3891:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3892:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3893:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3894:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3895:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3896:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3897:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3898:       /* } */
1.126     brouard  3899:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3900:        for (j=1;j<=nlstate+ndeath;j++){
                   3901:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3902:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3903:        }
1.214     brouard  3904:       
                   3905:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3906:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3907:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3908:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3909:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3910:          and mw[mi+1][i]. dh depends on stepm.*/
                   3911:        newm=savm;
1.247     brouard  3912:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3913:        cov[2]=agexact;
                   3914:        if(nagesqr==1)
                   3915:          cov[3]= agexact*agexact;
                   3916:        for (kk=1; kk<=cptcovage;kk++) {
                   3917:          if(!FixedV[Tvar[Tage[kk]]])
                   3918:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3919:          else
                   3920:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3921:        }
                   3922:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3923:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3924:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3925:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3926:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3927:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3928:        savm=oldm;
                   3929:        oldm=newm;
1.126     brouard  3930:       } /* end mult */
                   3931:       
                   3932:       s1=s[mw[mi][i]][i];
                   3933:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3934:       /* if(s2==-1){ */
1.268     brouard  3935:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3936:       /*       /\* exit(1); *\/ */
                   3937:       /* } */
1.126     brouard  3938:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3939:       /* bias is positive if real duration
                   3940:        * is higher than the multiple of stepm and negative otherwise.
                   3941:        */
                   3942:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3943:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3944:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3945:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3946:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3947:        lli= log(survp);
1.126     brouard  3948:       }else if (mle==1){
1.242     brouard  3949:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3950:       } else if(mle==2){
1.242     brouard  3951:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3952:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3953:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3954:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3955:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3956:       } else{  /* mle=0 back to 1 */
1.242     brouard  3957:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3958:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3959:       } /* End of if */
                   3960:       ipmx +=1;
                   3961:       sw += weight[i];
                   3962:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3963:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3964:       if(globpr){
1.246     brouard  3965:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3966:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3967:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3968:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3969:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3970:          llt +=ll[k]*gipmx/gsw;
                   3971:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3972:        }
                   3973:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3974:       }
1.232     brouard  3975:        } /* end of wave */
                   3976: } /* end of individual */
                   3977: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3978: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3979: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3980: if(globpr==0){ /* First time we count the contributions and weights */
                   3981:        gipmx=ipmx;
                   3982:        gsw=sw;
                   3983: }
                   3984: return -l;
1.126     brouard  3985: }
                   3986: 
                   3987: 
                   3988: /*************** function likelione ***********/
1.292     brouard  3989: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*func)(double []))
1.126     brouard  3990: {
                   3991:   /* This routine should help understanding what is done with 
                   3992:      the selection of individuals/waves and
                   3993:      to check the exact contribution to the likelihood.
                   3994:      Plotting could be done.
                   3995:    */
                   3996:   int k;
                   3997: 
                   3998:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3999:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  4000:     strcat(fileresilk,fileresu);
1.126     brouard  4001:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   4002:       printf("Problem with resultfile: %s\n", fileresilk);
                   4003:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   4004:     }
1.214     brouard  4005:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   4006:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  4007:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   4008:     for(k=1; k<=nlstate; k++) 
                   4009:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   4010:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   4011:   }
                   4012: 
1.292     brouard  4013:   *fretone=(*func)(p);
1.126     brouard  4014:   if(*globpri !=0){
                   4015:     fclose(ficresilk);
1.205     brouard  4016:     if (mle ==0)
                   4017:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   4018:     else if(mle >=1)
                   4019:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   4020:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  4021:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  4022:       
                   4023:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  4024:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  4025: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   4026:     }
1.207     brouard  4027:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  4028: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4029:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  4030: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4031:     fflush(fichtm);
1.205     brouard  4032:   }
1.126     brouard  4033:   return;
                   4034: }
                   4035: 
                   4036: 
                   4037: /*********** Maximum Likelihood Estimation ***************/
                   4038: 
                   4039: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   4040: {
1.165     brouard  4041:   int i,j, iter=0;
1.126     brouard  4042:   double **xi;
                   4043:   double fret;
                   4044:   double fretone; /* Only one call to likelihood */
                   4045:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  4046: 
                   4047: #ifdef NLOPT
                   4048:   int creturn;
                   4049:   nlopt_opt opt;
                   4050:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   4051:   double *lb;
                   4052:   double minf; /* the minimum objective value, upon return */
                   4053:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   4054:   myfunc_data dinst, *d = &dinst;
                   4055: #endif
                   4056: 
                   4057: 
1.126     brouard  4058:   xi=matrix(1,npar,1,npar);
                   4059:   for (i=1;i<=npar;i++)
                   4060:     for (j=1;j<=npar;j++)
                   4061:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   4062:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  4063:   strcpy(filerespow,"POW_"); 
1.126     brouard  4064:   strcat(filerespow,fileres);
                   4065:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   4066:     printf("Problem with resultfile: %s\n", filerespow);
                   4067:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   4068:   }
                   4069:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   4070:   for (i=1;i<=nlstate;i++)
                   4071:     for(j=1;j<=nlstate+ndeath;j++)
                   4072:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   4073:   fprintf(ficrespow,"\n");
1.162     brouard  4074: #ifdef POWELL
1.126     brouard  4075:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  4076: #endif
1.126     brouard  4077: 
1.162     brouard  4078: #ifdef NLOPT
                   4079: #ifdef NEWUOA
                   4080:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   4081: #else
                   4082:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   4083: #endif
                   4084:   lb=vector(0,npar-1);
                   4085:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   4086:   nlopt_set_lower_bounds(opt, lb);
                   4087:   nlopt_set_initial_step1(opt, 0.1);
                   4088:   
                   4089:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   4090:   d->function = func;
                   4091:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   4092:   nlopt_set_min_objective(opt, myfunc, d);
                   4093:   nlopt_set_xtol_rel(opt, ftol);
                   4094:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   4095:     printf("nlopt failed! %d\n",creturn); 
                   4096:   }
                   4097:   else {
                   4098:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4099:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4100:     iter=1; /* not equal */
                   4101:   }
                   4102:   nlopt_destroy(opt);
                   4103: #endif
1.126     brouard  4104:   free_matrix(xi,1,npar,1,npar);
                   4105:   fclose(ficrespow);
1.203     brouard  4106:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4107:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4108:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4109: 
                   4110: }
                   4111: 
                   4112: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4113: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4114: {
                   4115:   double  **a,**y,*x,pd;
1.203     brouard  4116:   /* double **hess; */
1.164     brouard  4117:   int i, j;
1.126     brouard  4118:   int *indx;
                   4119: 
                   4120:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4121:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4122:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4123:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4124:   double gompertz(double p[]);
1.203     brouard  4125:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4126: 
                   4127:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4128:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4129:   for (i=1;i<=npar;i++){
1.203     brouard  4130:     printf("%d-",i);fflush(stdout);
                   4131:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4132:    
                   4133:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4134:     
                   4135:     /*  printf(" %f ",p[i]);
                   4136:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4137:   }
                   4138:   
                   4139:   for (i=1;i<=npar;i++) {
                   4140:     for (j=1;j<=npar;j++)  {
                   4141:       if (j>i) { 
1.203     brouard  4142:        printf(".%d-%d",i,j);fflush(stdout);
                   4143:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4144:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4145:        
                   4146:        hess[j][i]=hess[i][j];    
                   4147:        /*printf(" %lf ",hess[i][j]);*/
                   4148:       }
                   4149:     }
                   4150:   }
                   4151:   printf("\n");
                   4152:   fprintf(ficlog,"\n");
                   4153: 
                   4154:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4155:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4156:   
                   4157:   a=matrix(1,npar,1,npar);
                   4158:   y=matrix(1,npar,1,npar);
                   4159:   x=vector(1,npar);
                   4160:   indx=ivector(1,npar);
                   4161:   for (i=1;i<=npar;i++)
                   4162:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4163:   ludcmp(a,npar,indx,&pd);
                   4164: 
                   4165:   for (j=1;j<=npar;j++) {
                   4166:     for (i=1;i<=npar;i++) x[i]=0;
                   4167:     x[j]=1;
                   4168:     lubksb(a,npar,indx,x);
                   4169:     for (i=1;i<=npar;i++){ 
                   4170:       matcov[i][j]=x[i];
                   4171:     }
                   4172:   }
                   4173: 
                   4174:   printf("\n#Hessian matrix#\n");
                   4175:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4176:   for (i=1;i<=npar;i++) { 
                   4177:     for (j=1;j<=npar;j++) { 
1.203     brouard  4178:       printf("%.6e ",hess[i][j]);
                   4179:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4180:     }
                   4181:     printf("\n");
                   4182:     fprintf(ficlog,"\n");
                   4183:   }
                   4184: 
1.203     brouard  4185:   /* printf("\n#Covariance matrix#\n"); */
                   4186:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4187:   /* for (i=1;i<=npar;i++) {  */
                   4188:   /*   for (j=1;j<=npar;j++) {  */
                   4189:   /*     printf("%.6e ",matcov[i][j]); */
                   4190:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4191:   /*   } */
                   4192:   /*   printf("\n"); */
                   4193:   /*   fprintf(ficlog,"\n"); */
                   4194:   /* } */
                   4195: 
1.126     brouard  4196:   /* Recompute Inverse */
1.203     brouard  4197:   /* for (i=1;i<=npar;i++) */
                   4198:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4199:   /* ludcmp(a,npar,indx,&pd); */
                   4200: 
                   4201:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4202: 
                   4203:   /* for (j=1;j<=npar;j++) { */
                   4204:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4205:   /*   x[j]=1; */
                   4206:   /*   lubksb(a,npar,indx,x); */
                   4207:   /*   for (i=1;i<=npar;i++){  */
                   4208:   /*     y[i][j]=x[i]; */
                   4209:   /*     printf("%.3e ",y[i][j]); */
                   4210:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4211:   /*   } */
                   4212:   /*   printf("\n"); */
                   4213:   /*   fprintf(ficlog,"\n"); */
                   4214:   /* } */
                   4215: 
                   4216:   /* Verifying the inverse matrix */
                   4217: #ifdef DEBUGHESS
                   4218:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4219: 
1.203     brouard  4220:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4221:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4222: 
                   4223:   for (j=1;j<=npar;j++) {
                   4224:     for (i=1;i<=npar;i++){ 
1.203     brouard  4225:       printf("%.2f ",y[i][j]);
                   4226:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4227:     }
                   4228:     printf("\n");
                   4229:     fprintf(ficlog,"\n");
                   4230:   }
1.203     brouard  4231: #endif
1.126     brouard  4232: 
                   4233:   free_matrix(a,1,npar,1,npar);
                   4234:   free_matrix(y,1,npar,1,npar);
                   4235:   free_vector(x,1,npar);
                   4236:   free_ivector(indx,1,npar);
1.203     brouard  4237:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4238: 
                   4239: 
                   4240: }
                   4241: 
                   4242: /*************** hessian matrix ****************/
                   4243: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4244: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4245:   int i;
                   4246:   int l=1, lmax=20;
1.203     brouard  4247:   double k1,k2, res, fx;
1.132     brouard  4248:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4249:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4250:   int k=0,kmax=10;
                   4251:   double l1;
                   4252: 
                   4253:   fx=func(x);
                   4254:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4255:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4256:     l1=pow(10,l);
                   4257:     delts=delt;
                   4258:     for(k=1 ; k <kmax; k=k+1){
                   4259:       delt = delta*(l1*k);
                   4260:       p2[theta]=x[theta] +delt;
1.145     brouard  4261:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4262:       p2[theta]=x[theta]-delt;
                   4263:       k2=func(p2)-fx;
                   4264:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4265:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4266:       
1.203     brouard  4267: #ifdef DEBUGHESSII
1.126     brouard  4268:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4269:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4270: #endif
                   4271:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4272:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4273:        k=kmax;
                   4274:       }
                   4275:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4276:        k=kmax; l=lmax*10;
1.126     brouard  4277:       }
                   4278:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4279:        delts=delt;
                   4280:       }
1.203     brouard  4281:     } /* End loop k */
1.126     brouard  4282:   }
                   4283:   delti[theta]=delts;
                   4284:   return res; 
                   4285:   
                   4286: }
                   4287: 
1.203     brouard  4288: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4289: {
                   4290:   int i;
1.164     brouard  4291:   int l=1, lmax=20;
1.126     brouard  4292:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4293:   double p2[MAXPARM+1];
1.203     brouard  4294:   int k, kmax=1;
                   4295:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4296: 
                   4297:   int firstime=0;
1.203     brouard  4298:   
1.126     brouard  4299:   fx=func(x);
1.203     brouard  4300:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4301:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4302:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4303:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4304:     k1=func(p2)-fx;
                   4305:   
1.203     brouard  4306:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4307:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4308:     k2=func(p2)-fx;
                   4309:   
1.203     brouard  4310:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4311:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4312:     k3=func(p2)-fx;
                   4313:   
1.203     brouard  4314:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4315:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4316:     k4=func(p2)-fx;
1.203     brouard  4317:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4318:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4319:       firstime=1;
1.203     brouard  4320:       kmax=kmax+10;
1.208     brouard  4321:     }
                   4322:     if(kmax >=10 || firstime ==1){
1.246     brouard  4323:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4324:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4325:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4326:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4327:     }
                   4328: #ifdef DEBUGHESSIJ
                   4329:     v1=hess[thetai][thetai];
                   4330:     v2=hess[thetaj][thetaj];
                   4331:     cv12=res;
                   4332:     /* Computing eigen value of Hessian matrix */
                   4333:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4334:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4335:     if ((lc2 <0) || (lc1 <0) ){
                   4336:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4337:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4338:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4339:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4340:     }
1.126     brouard  4341: #endif
                   4342:   }
                   4343:   return res;
                   4344: }
                   4345: 
1.203     brouard  4346:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4347: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4348: /* { */
                   4349: /*   int i; */
                   4350: /*   int l=1, lmax=20; */
                   4351: /*   double k1,k2,k3,k4,res,fx; */
                   4352: /*   double p2[MAXPARM+1]; */
                   4353: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4354: /*   int k=0,kmax=10; */
                   4355: /*   double l1; */
                   4356:   
                   4357: /*   fx=func(x); */
                   4358: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4359: /*     l1=pow(10,l); */
                   4360: /*     delts=delt; */
                   4361: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4362: /*       delt = delti*(l1*k); */
                   4363: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4364: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4365: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4366: /*       k1=func(p2)-fx; */
                   4367:       
                   4368: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4369: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4370: /*       k2=func(p2)-fx; */
                   4371:       
                   4372: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4373: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4374: /*       k3=func(p2)-fx; */
                   4375:       
                   4376: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4377: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4378: /*       k4=func(p2)-fx; */
                   4379: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4380: /* #ifdef DEBUGHESSIJ */
                   4381: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4382: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4383: /* #endif */
                   4384: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4385: /*     k=kmax; */
                   4386: /*       } */
                   4387: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4388: /*     k=kmax; l=lmax*10; */
                   4389: /*       } */
                   4390: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4391: /*     delts=delt; */
                   4392: /*       } */
                   4393: /*     } /\* End loop k *\/ */
                   4394: /*   } */
                   4395: /*   delti[theta]=delts; */
                   4396: /*   return res;  */
                   4397: /* } */
                   4398: 
                   4399: 
1.126     brouard  4400: /************** Inverse of matrix **************/
                   4401: void ludcmp(double **a, int n, int *indx, double *d) 
                   4402: { 
                   4403:   int i,imax,j,k; 
                   4404:   double big,dum,sum,temp; 
                   4405:   double *vv; 
                   4406:  
                   4407:   vv=vector(1,n); 
                   4408:   *d=1.0; 
                   4409:   for (i=1;i<=n;i++) { 
                   4410:     big=0.0; 
                   4411:     for (j=1;j<=n;j++) 
                   4412:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4413:     if (big == 0.0){
                   4414:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4415:       for (j=1;j<=n;j++) {
                   4416:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4417:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4418:       }
                   4419:       fflush(ficlog);
                   4420:       fclose(ficlog);
                   4421:       nrerror("Singular matrix in routine ludcmp"); 
                   4422:     }
1.126     brouard  4423:     vv[i]=1.0/big; 
                   4424:   } 
                   4425:   for (j=1;j<=n;j++) { 
                   4426:     for (i=1;i<j;i++) { 
                   4427:       sum=a[i][j]; 
                   4428:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4429:       a[i][j]=sum; 
                   4430:     } 
                   4431:     big=0.0; 
                   4432:     for (i=j;i<=n;i++) { 
                   4433:       sum=a[i][j]; 
                   4434:       for (k=1;k<j;k++) 
                   4435:        sum -= a[i][k]*a[k][j]; 
                   4436:       a[i][j]=sum; 
                   4437:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4438:        big=dum; 
                   4439:        imax=i; 
                   4440:       } 
                   4441:     } 
                   4442:     if (j != imax) { 
                   4443:       for (k=1;k<=n;k++) { 
                   4444:        dum=a[imax][k]; 
                   4445:        a[imax][k]=a[j][k]; 
                   4446:        a[j][k]=dum; 
                   4447:       } 
                   4448:       *d = -(*d); 
                   4449:       vv[imax]=vv[j]; 
                   4450:     } 
                   4451:     indx[j]=imax; 
                   4452:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4453:     if (j != n) { 
                   4454:       dum=1.0/(a[j][j]); 
                   4455:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4456:     } 
                   4457:   } 
                   4458:   free_vector(vv,1,n);  /* Doesn't work */
                   4459: ;
                   4460: } 
                   4461: 
                   4462: void lubksb(double **a, int n, int *indx, double b[]) 
                   4463: { 
                   4464:   int i,ii=0,ip,j; 
                   4465:   double sum; 
                   4466:  
                   4467:   for (i=1;i<=n;i++) { 
                   4468:     ip=indx[i]; 
                   4469:     sum=b[ip]; 
                   4470:     b[ip]=b[i]; 
                   4471:     if (ii) 
                   4472:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4473:     else if (sum) ii=i; 
                   4474:     b[i]=sum; 
                   4475:   } 
                   4476:   for (i=n;i>=1;i--) { 
                   4477:     sum=b[i]; 
                   4478:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4479:     b[i]=sum/a[i][i]; 
                   4480:   } 
                   4481: } 
                   4482: 
                   4483: void pstamp(FILE *fichier)
                   4484: {
1.196     brouard  4485:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4486: }
                   4487: 
1.297     brouard  4488: void date2dmy(double date,double *day, double *month, double *year){
                   4489:   double yp=0., yp1=0., yp2=0.;
                   4490:   
                   4491:   yp1=modf(date,&yp);/* extracts integral of date in yp  and
                   4492:                        fractional in yp1 */
                   4493:   *year=yp;
                   4494:   yp2=modf((yp1*12),&yp);
                   4495:   *month=yp;
                   4496:   yp1=modf((yp2*30.5),&yp);
                   4497:   *day=yp;
                   4498:   if(*day==0) *day=1;
                   4499:   if(*month==0) *month=1;
                   4500: }
                   4501: 
1.253     brouard  4502: 
                   4503: 
1.126     brouard  4504: /************ Frequencies ********************/
1.251     brouard  4505: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4506:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4507:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4508: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4509:   
1.265     brouard  4510:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4511:   int iind=0, iage=0;
                   4512:   int mi; /* Effective wave */
                   4513:   int first;
                   4514:   double ***freq; /* Frequencies */
1.268     brouard  4515:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4516:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4517:   double *meanq, *stdq, *idq;
1.226     brouard  4518:   double **meanqt;
                   4519:   double *pp, **prop, *posprop, *pospropt;
                   4520:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4521:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4522:   double agebegin, ageend;
                   4523:     
                   4524:   pp=vector(1,nlstate);
1.251     brouard  4525:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4526:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4527:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4528:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4529:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4530:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4531:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4532:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4533:   strcpy(fileresp,"P_");
                   4534:   strcat(fileresp,fileresu);
                   4535:   /*strcat(fileresphtm,fileresu);*/
                   4536:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4537:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4538:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4539:     exit(0);
                   4540:   }
1.240     brouard  4541:   
1.226     brouard  4542:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4543:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4544:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4545:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4546:     fflush(ficlog);
                   4547:     exit(70); 
                   4548:   }
                   4549:   else{
                   4550:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4551: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4552: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4553:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4554:   }
1.237     brouard  4555:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4556:   
1.226     brouard  4557:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4558:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4559:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4560:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4561:     fflush(ficlog);
                   4562:     exit(70); 
1.240     brouard  4563:   } else{
1.226     brouard  4564:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4565: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4566: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4567:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4568:   }
1.240     brouard  4569:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4570:   
1.253     brouard  4571:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4572:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4573:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4574:   j1=0;
1.126     brouard  4575:   
1.227     brouard  4576:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4577:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4578:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4579:   
                   4580:   
1.226     brouard  4581:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4582:      reference=low_education V1=0,V2=0
                   4583:      med_educ                V1=1 V2=0, 
                   4584:      high_educ               V1=0 V2=1
                   4585:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4586:   */
1.249     brouard  4587:   dateintsum=0;
                   4588:   k2cpt=0;
                   4589: 
1.253     brouard  4590:   if(cptcoveff == 0 )
1.265     brouard  4591:     nl=1;  /* Constant and age model only */
1.253     brouard  4592:   else
                   4593:     nl=2;
1.265     brouard  4594: 
                   4595:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4596:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4597:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4598:    *     freq[s1][s2][iage] =0.
                   4599:    *     Loop on iind
                   4600:    *       ++freq[s1][s2][iage] weighted
                   4601:    *     end iind
                   4602:    *     if covariate and j!0
                   4603:    *       headers Variable on one line
                   4604:    *     endif cov j!=0
                   4605:    *     header of frequency table by age
                   4606:    *     Loop on age
                   4607:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4608:    *       pos+=freq[s1][s2][iage] weighted
                   4609:    *       Loop on s1 initial state
                   4610:    *         fprintf(ficresp
                   4611:    *       end s1
                   4612:    *     end age
                   4613:    *     if j!=0 computes starting values
                   4614:    *     end compute starting values
                   4615:    *   end j1
                   4616:    * end nl 
                   4617:    */
1.253     brouard  4618:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4619:     if(nj==1)
                   4620:       j=0;  /* First pass for the constant */
1.265     brouard  4621:     else{
1.253     brouard  4622:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4623:     }
1.251     brouard  4624:     first=1;
1.265     brouard  4625:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4626:       posproptt=0.;
                   4627:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4628:        scanf("%d", i);*/
                   4629:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4630:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4631:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4632:            freq[i][s2][m]=0;
1.251     brouard  4633:       
                   4634:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4635:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4636:          prop[i][m]=0;
                   4637:        posprop[i]=0;
                   4638:        pospropt[i]=0;
                   4639:       }
1.283     brouard  4640:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4641:         idq[z1]=0.;
                   4642:         meanq[z1]=0.;
                   4643:         stdq[z1]=0.;
1.283     brouard  4644:       }
                   4645:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4646:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4647:       /*         meanqt[m][z1]=0.; */
                   4648:       /*       } */
                   4649:       /* }       */
1.251     brouard  4650:       /* dateintsum=0; */
                   4651:       /* k2cpt=0; */
                   4652:       
1.265     brouard  4653:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4654:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4655:        bool=1;
                   4656:        if(j !=0){
                   4657:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4658:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4659:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4660:                /* if(Tvaraff[z1] ==-20){ */
                   4661:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4662:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4663:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4664:                /* }else  */
                   4665:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4666:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4667:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4668:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4669:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4670:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4671:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4672:                } /* Onlyf fixed */
                   4673:              } /* end z1 */
                   4674:            } /* cptcovn > 0 */
                   4675:          } /* end any */
                   4676:        }/* end j==0 */
1.265     brouard  4677:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4678:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4679:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4680:            m=mw[mi][iind];
                   4681:            if(j!=0){
                   4682:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4683:                for (z1=1; z1<=cptcoveff; z1++) {
                   4684:                  if( Fixed[Tmodelind[z1]]==1){
                   4685:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4686:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4687:                                                                                      value is -1, we don't select. It differs from the 
                   4688:                                                                                      constant and age model which counts them. */
                   4689:                      bool=0; /* not selected */
                   4690:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4691:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4692:                      bool=0;
                   4693:                    }
                   4694:                  }
                   4695:                }
                   4696:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4697:            } /* end j==0 */
                   4698:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4699:            if(bool==1){ /*Selected */
1.251     brouard  4700:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4701:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4702:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4703:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4704:              if(m >=firstpass && m <=lastpass){
                   4705:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4706:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4707:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4708:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4709:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4710:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4711:                if (m<lastpass) {
                   4712:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4713:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4714:                  if(s[m][iind]==-1)
                   4715:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4716:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.311     brouard  4717:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean on known values only */
                   4718:                    if(!isnan(covar[ncovcol+z1][iind])){
                   4719:                        idq[z1]=idq[z1]+weight[iind];
                   4720:                        meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4721:                        /* stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; *//*error*/
                   4722:                        stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4723:                    }
1.284     brouard  4724:                  }
1.251     brouard  4725:                  /* if((int)agev[m][iind] == 55) */
                   4726:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4727:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4728:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4729:                }
1.251     brouard  4730:              } /* end if between passes */  
                   4731:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4732:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4733:                k2cpt++;
                   4734:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4735:              }
1.251     brouard  4736:            }else{
                   4737:              bool=1;
                   4738:            }/* end bool 2 */
                   4739:          } /* end m */
1.284     brouard  4740:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4741:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4742:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4743:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4744:          /* } */
1.251     brouard  4745:        } /* end bool */
                   4746:       } /* end iind = 1 to imx */
                   4747:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4748:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4749:       
                   4750:       
                   4751:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4752:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4753:         pstamp(ficresp);
1.251     brouard  4754:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4755:         pstamp(ficresp);
1.251     brouard  4756:        printf( "\n#********** Variable "); 
                   4757:        fprintf(ficresp, "\n#********** Variable "); 
                   4758:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4759:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4760:        fprintf(ficlog, "\n#********** Variable "); 
                   4761:        for (z1=1; z1<=cptcoveff; z1++){
                   4762:          if(!FixedV[Tvaraff[z1]]){
                   4763:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4764:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4765:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4766:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4767:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4768:          }else{
1.251     brouard  4769:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4770:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4771:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4772:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4773:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4774:          }
                   4775:        }
                   4776:        printf( "**********\n#");
                   4777:        fprintf(ficresp, "**********\n#");
                   4778:        fprintf(ficresphtm, "**********</h3>\n");
                   4779:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4780:        fprintf(ficlog, "**********\n");
                   4781:       }
1.284     brouard  4782:       /*
                   4783:        Printing means of quantitative variables if any
                   4784:       */
                   4785:       for (z1=1; z1<= nqfveff; z1++) {
1.311     brouard  4786:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.3g (weighted) individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.312     brouard  4787:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
1.284     brouard  4788:        if(weightopt==1){
                   4789:          printf(" Weighted mean and standard deviation of");
                   4790:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4791:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4792:        }
1.311     brouard  4793:        /* mu = \frac{w x}{\sum w}
                   4794:            var = \frac{\sum w (x-mu)^2}{\sum w} = \frac{w x^2}{\sum w} - mu^2 
                   4795:        */
                   4796:        printf(" fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   4797:        fprintf(ficlog," fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   4798:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.3g (weighted) representatives of the population : %8.5g (%8.5g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
1.284     brouard  4799:       }
                   4800:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4801:       /*       for(m=1;m<=lastpass;m++){ */
                   4802:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4803:       /*   } */
                   4804:       /* } */
1.283     brouard  4805: 
1.251     brouard  4806:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4807:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4808:         fprintf(ficresp, " Age");
                   4809:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4810:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4811:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4812:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4813:       }
1.265     brouard  4814:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4815:       fprintf(ficresphtm, "\n");
                   4816:       
                   4817:       /* Header of frequency table by age */
                   4818:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4819:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4820:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4821:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4822:          if(s2!=0 && m!=0)
                   4823:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4824:        }
1.226     brouard  4825:       }
1.251     brouard  4826:       fprintf(ficresphtmfr, "\n");
                   4827:     
                   4828:       /* For each age */
                   4829:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4830:        fprintf(ficresphtm,"<tr>");
                   4831:        if(iage==iagemax+1){
                   4832:          fprintf(ficlog,"1");
                   4833:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4834:        }else if(iage==iagemax+2){
                   4835:          fprintf(ficlog,"0");
                   4836:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4837:        }else if(iage==iagemax+3){
                   4838:          fprintf(ficlog,"Total");
                   4839:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4840:        }else{
1.240     brouard  4841:          if(first==1){
1.251     brouard  4842:            first=0;
                   4843:            printf("See log file for details...\n");
                   4844:          }
                   4845:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4846:          fprintf(ficlog,"Age %d", iage);
                   4847:        }
1.265     brouard  4848:        for(s1=1; s1 <=nlstate ; s1++){
                   4849:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4850:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4851:        }
1.265     brouard  4852:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4853:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4854:            pos += freq[s1][m][iage];
                   4855:          if(pp[s1]>=1.e-10){
1.251     brouard  4856:            if(first==1){
1.265     brouard  4857:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4858:            }
1.265     brouard  4859:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4860:          }else{
                   4861:            if(first==1)
1.265     brouard  4862:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4863:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4864:          }
                   4865:        }
                   4866:       
1.265     brouard  4867:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4868:          /* posprop[s1]=0; */
                   4869:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4870:            pp[s1] += freq[s1][m][iage];
                   4871:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4872:       
                   4873:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4874:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4875:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4876:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4877:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4878:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4879:        }
                   4880:        
                   4881:        /* Writing ficresp */
                   4882:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4883:           if( iage <= iagemax){
                   4884:            fprintf(ficresp," %d",iage);
                   4885:           }
                   4886:         }else if( nj==2){
                   4887:           if( iage <= iagemax){
                   4888:            fprintf(ficresp," %d",iage);
                   4889:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4890:           }
1.240     brouard  4891:        }
1.265     brouard  4892:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4893:          if(pos>=1.e-5){
1.251     brouard  4894:            if(first==1)
1.265     brouard  4895:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4896:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4897:          }else{
                   4898:            if(first==1)
1.265     brouard  4899:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4900:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4901:          }
                   4902:          if( iage <= iagemax){
                   4903:            if(pos>=1.e-5){
1.265     brouard  4904:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4905:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4906:               }else if( nj==2){
                   4907:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4908:               }
                   4909:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4910:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4911:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4912:            } else{
                   4913:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4914:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4915:            }
1.240     brouard  4916:          }
1.265     brouard  4917:          pospropt[s1] +=posprop[s1];
                   4918:        } /* end loop s1 */
1.251     brouard  4919:        /* pospropt=0.; */
1.265     brouard  4920:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4921:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4922:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4923:              if(first==1){
1.265     brouard  4924:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4925:              }
1.265     brouard  4926:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4927:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4928:            }
1.265     brouard  4929:            if(s1!=0 && m!=0)
                   4930:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4931:          }
1.265     brouard  4932:        } /* end loop s1 */
1.251     brouard  4933:        posproptt=0.; 
1.265     brouard  4934:        for(s1=1; s1 <=nlstate; s1++){
                   4935:          posproptt += pospropt[s1];
1.251     brouard  4936:        }
                   4937:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4938:        fprintf(ficresphtm,"</tr>\n");
                   4939:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4940:          if(iage <= iagemax)
                   4941:            fprintf(ficresp,"\n");
1.240     brouard  4942:        }
1.251     brouard  4943:        if(first==1)
                   4944:          printf("Others in log...\n");
                   4945:        fprintf(ficlog,"\n");
                   4946:       } /* end loop age iage */
1.265     brouard  4947:       
1.251     brouard  4948:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4949:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4950:        if(posproptt < 1.e-5){
1.265     brouard  4951:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4952:        }else{
1.265     brouard  4953:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4954:        }
1.226     brouard  4955:       }
1.251     brouard  4956:       fprintf(ficresphtm,"</tr>\n");
                   4957:       fprintf(ficresphtm,"</table>\n");
                   4958:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4959:       if(posproptt < 1.e-5){
1.251     brouard  4960:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4961:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4962:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4963:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4964:        invalidvarcomb[j1]=1;
1.226     brouard  4965:       }else{
1.251     brouard  4966:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4967:        invalidvarcomb[j1]=0;
1.226     brouard  4968:       }
1.251     brouard  4969:       fprintf(ficresphtmfr,"</table>\n");
                   4970:       fprintf(ficlog,"\n");
                   4971:       if(j!=0){
                   4972:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4973:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4974:          for(k=1; k <=(nlstate+ndeath); k++){
                   4975:            if (k != i) {
1.265     brouard  4976:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4977:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4978:                  if(j1==1){ /* All dummy covariates to zero */
                   4979:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4980:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4981:                    printf("%d%d ",i,k);
                   4982:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4983:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4984:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4985:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4986:                  }
1.253     brouard  4987:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4988:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4989:                    x[iage]= (double)iage;
                   4990:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4991:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4992:                  }
1.268     brouard  4993:                  /* Some are not finite, but linreg will ignore these ages */
                   4994:                  no=0;
1.253     brouard  4995:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4996:                  pstart[s1]=b;
                   4997:                  pstart[s1-1]=a;
1.252     brouard  4998:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4999:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   5000:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  5001:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  5002:                  printf("%d%d ",i,k);
                   5003:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  5004:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  5005:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   5006:                  ;
                   5007:                }
                   5008:                /* printf("%12.7f )", param[i][jj][k]); */
                   5009:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5010:                s1++; 
1.251     brouard  5011:              } /* end jj */
                   5012:            } /* end k!= i */
                   5013:          } /* end k */
1.265     brouard  5014:        } /* end i, s1 */
1.251     brouard  5015:       } /* end j !=0 */
                   5016:     } /* end selected combination of covariate j1 */
                   5017:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   5018:       printf("#Freqsummary: Starting values for the constants:\n");
                   5019:       fprintf(ficlog,"\n");
1.265     brouard  5020:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  5021:        for(k=1; k <=(nlstate+ndeath); k++){
                   5022:          if (k != i) {
                   5023:            printf("%d%d ",i,k);
                   5024:            fprintf(ficlog,"%d%d ",i,k);
                   5025:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  5026:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  5027:              if(jj==1){ /* Age has to be done */
1.265     brouard  5028:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   5029:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   5030:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  5031:              }
                   5032:              /* printf("%12.7f )", param[i][jj][k]); */
                   5033:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5034:              s1++; 
1.250     brouard  5035:            }
1.251     brouard  5036:            printf("\n");
                   5037:            fprintf(ficlog,"\n");
1.250     brouard  5038:          }
                   5039:        }
1.284     brouard  5040:       } /* end of state i */
1.251     brouard  5041:       printf("#Freqsummary\n");
                   5042:       fprintf(ficlog,"\n");
1.265     brouard  5043:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   5044:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   5045:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   5046:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5047:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5048:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   5049:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   5050:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  5051:          /* } */
                   5052:        }
1.265     brouard  5053:       } /* end loop s1 */
1.251     brouard  5054:       
                   5055:       printf("\n");
                   5056:       fprintf(ficlog,"\n");
                   5057:     } /* end j=0 */
1.249     brouard  5058:   } /* end j */
1.252     brouard  5059: 
1.253     brouard  5060:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  5061:     for(i=1, jk=1; i <=nlstate; i++){
                   5062:       for(j=1; j <=nlstate+ndeath; j++){
                   5063:        if(j!=i){
                   5064:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   5065:          printf("%1d%1d",i,j);
                   5066:          fprintf(ficparo,"%1d%1d",i,j);
                   5067:          for(k=1; k<=ncovmodel;k++){
                   5068:            /*    printf(" %lf",param[i][j][k]); */
                   5069:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   5070:            p[jk]=pstart[jk];
                   5071:            printf(" %f ",pstart[jk]);
                   5072:            fprintf(ficparo," %f ",pstart[jk]);
                   5073:            jk++;
                   5074:          }
                   5075:          printf("\n");
                   5076:          fprintf(ficparo,"\n");
                   5077:        }
                   5078:       }
                   5079:     }
                   5080:   } /* end mle=-2 */
1.226     brouard  5081:   dateintmean=dateintsum/k2cpt; 
1.296     brouard  5082:   date2dmy(dateintmean,&jintmean,&mintmean,&aintmean);
1.240     brouard  5083:   
1.226     brouard  5084:   fclose(ficresp);
                   5085:   fclose(ficresphtm);
                   5086:   fclose(ficresphtmfr);
1.283     brouard  5087:   free_vector(idq,1,nqfveff);
1.226     brouard  5088:   free_vector(meanq,1,nqfveff);
1.284     brouard  5089:   free_vector(stdq,1,nqfveff);
1.226     brouard  5090:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  5091:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   5092:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  5093:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5094:   free_vector(pospropt,1,nlstate);
                   5095:   free_vector(posprop,1,nlstate);
1.251     brouard  5096:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5097:   free_vector(pp,1,nlstate);
                   5098:   /* End of freqsummary */
                   5099: }
1.126     brouard  5100: 
1.268     brouard  5101: /* Simple linear regression */
                   5102: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   5103: 
                   5104:   /* y=a+bx regression */
                   5105:   double   sumx = 0.0;                        /* sum of x                      */
                   5106:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   5107:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   5108:   double   sumy = 0.0;                        /* sum of y                      */
                   5109:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   5110:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   5111:   double yhat;
                   5112:   
                   5113:   double denom=0;
                   5114:   int i;
                   5115:   int ne=*no;
                   5116:   
                   5117:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5118:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5119:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5120:       continue;
                   5121:     }
                   5122:     ne=ne+1;
                   5123:     sumx  += x[i];       
                   5124:     sumx2 += x[i]*x[i];  
                   5125:     sumxy += x[i] * y[i];
                   5126:     sumy  += y[i];      
                   5127:     sumy2 += y[i]*y[i]; 
                   5128:     denom = (ne * sumx2 - sumx*sumx);
                   5129:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5130:   } 
                   5131:   
                   5132:   denom = (ne * sumx2 - sumx*sumx);
                   5133:   if (denom == 0) {
                   5134:     // vertical, slope m is infinity
                   5135:     *b = INFINITY;
                   5136:     *a = 0;
                   5137:     if (r) *r = 0;
                   5138:     return 1;
                   5139:   }
                   5140:   
                   5141:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5142:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5143:   if (r!=NULL) {
                   5144:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5145:       sqrt((sumx2 - sumx*sumx/ne) *
                   5146:           (sumy2 - sumy*sumy/ne));
                   5147:   }
                   5148:   *no=ne;
                   5149:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5150:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5151:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5152:       continue;
                   5153:     }
                   5154:     ne=ne+1;
                   5155:     yhat = y[i] - *a -*b* x[i];
                   5156:     sume2  += yhat * yhat ;       
                   5157:     
                   5158:     denom = (ne * sumx2 - sumx*sumx);
                   5159:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5160:   } 
                   5161:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5162:   *sa= *sb * sqrt(sumx2/ne);
                   5163:   
                   5164:   return 0; 
                   5165: }
                   5166: 
1.126     brouard  5167: /************ Prevalence ********************/
1.227     brouard  5168: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5169: {  
                   5170:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5171:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5172:      We still use firstpass and lastpass as another selection.
                   5173:   */
1.126     brouard  5174:  
1.227     brouard  5175:   int i, m, jk, j1, bool, z1,j, iv;
                   5176:   int mi; /* Effective wave */
                   5177:   int iage;
                   5178:   double agebegin, ageend;
                   5179: 
                   5180:   double **prop;
                   5181:   double posprop; 
                   5182:   double  y2; /* in fractional years */
                   5183:   int iagemin, iagemax;
                   5184:   int first; /** to stop verbosity which is redirected to log file */
                   5185: 
                   5186:   iagemin= (int) agemin;
                   5187:   iagemax= (int) agemax;
                   5188:   /*pp=vector(1,nlstate);*/
1.251     brouard  5189:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5190:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5191:   j1=0;
1.222     brouard  5192:   
1.227     brouard  5193:   /*j=cptcoveff;*/
                   5194:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5195:   
1.288     brouard  5196:   first=0;
1.227     brouard  5197:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5198:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5199:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5200:        prop[i][iage]=0.0;
                   5201:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5202:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5203:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5204:     
                   5205:     for (i=1; i<=imx; i++) { /* Each individual */
                   5206:       bool=1;
                   5207:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5208:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5209:        m=mw[mi][i];
                   5210:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5211:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5212:        for (z1=1; z1<=cptcoveff; z1++){
                   5213:          if( Fixed[Tmodelind[z1]]==1){
                   5214:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5215:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5216:              bool=0;
                   5217:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5218:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5219:              bool=0;
                   5220:            }
                   5221:        }
                   5222:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5223:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5224:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5225:          if(m >=firstpass && m <=lastpass){
                   5226:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5227:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5228:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5229:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5230:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5231:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5232:                exit(1);
                   5233:              }
                   5234:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5235:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5236:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5237:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5238:              } /* end valid statuses */ 
                   5239:            } /* end selection of dates */
                   5240:          } /* end selection of waves */
                   5241:        } /* end bool */
                   5242:       } /* end wave */
                   5243:     } /* end individual */
                   5244:     for(i=iagemin; i <= iagemax+3; i++){  
                   5245:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5246:        posprop += prop[jk][i]; 
                   5247:       } 
                   5248:       
                   5249:       for(jk=1; jk <=nlstate ; jk++){      
                   5250:        if( i <=  iagemax){ 
                   5251:          if(posprop>=1.e-5){ 
                   5252:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5253:          } else{
1.288     brouard  5254:            if(!first){
                   5255:              first=1;
1.266     brouard  5256:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5257:            }else{
1.288     brouard  5258:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5259:            }
                   5260:          }
                   5261:        } 
                   5262:       }/* end jk */ 
                   5263:     }/* end i */ 
1.222     brouard  5264:      /*} *//* end i1 */
1.227     brouard  5265:   } /* end j1 */
1.222     brouard  5266:   
1.227     brouard  5267:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5268:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5269:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5270: }  /* End of prevalence */
1.126     brouard  5271: 
                   5272: /************* Waves Concatenation ***************/
                   5273: 
                   5274: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5275: {
1.298     brouard  5276:   /* Concatenates waves: wav[i] is the number of effective (useful waves in the sense that a non interview is useless) of individual i.
1.126     brouard  5277:      Death is a valid wave (if date is known).
                   5278:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5279:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
1.298     brouard  5280:      and mw[mi+1][i]. dh depends on stepm. s[m][i] exists for any wave from firstpass to lastpass
1.227     brouard  5281:   */
1.126     brouard  5282: 
1.224     brouard  5283:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5284:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5285:      double sum=0., jmean=0.;*/
1.224     brouard  5286:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5287:   int j, k=0,jk, ju, jl;
                   5288:   double sum=0.;
                   5289:   first=0;
1.214     brouard  5290:   firstwo=0;
1.217     brouard  5291:   firsthree=0;
1.218     brouard  5292:   firstfour=0;
1.164     brouard  5293:   jmin=100000;
1.126     brouard  5294:   jmax=-1;
                   5295:   jmean=0.;
1.224     brouard  5296: 
                   5297: /* Treating live states */
1.214     brouard  5298:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5299:     mi=0;  /* First valid wave */
1.227     brouard  5300:     mli=0; /* Last valid wave */
1.309     brouard  5301:     m=firstpass;  /* Loop on waves */
                   5302:     while(s[m][i] <= nlstate){  /* a live state or unknown state  */
1.227     brouard  5303:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5304:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5305:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
1.309     brouard  5306:        mw[++mi][i]=m; /* Valid wave: incrementing mi and updating mi; mw[mi] is the wave number of mi_th valid transition   */
1.227     brouard  5307:        mli=m;
1.224     brouard  5308:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5309:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5310:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5311:       }
1.309     brouard  5312:       else{ /* m = lastpass, eventual special issue with warning */
1.224     brouard  5313: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5314:        break;
1.224     brouard  5315: #else
1.309     brouard  5316:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){ /* case -2 (vital status unknown is warned later */
1.227     brouard  5317:          if(firsthree == 0){
1.302     brouard  5318:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5319:            firsthree=1;
                   5320:          }
1.302     brouard  5321:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.309     brouard  5322:          mw[++mi][i]=m; /* Valid transition with unknown status */
1.227     brouard  5323:          mli=m;
                   5324:        }
                   5325:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5326:          nbwarn++;
1.309     brouard  5327:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified?not a transition */
1.227     brouard  5328:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5329:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5330:          }
                   5331:          break;
                   5332:        }
                   5333:        break;
1.224     brouard  5334: #endif
1.227     brouard  5335:       }/* End m >= lastpass */
1.126     brouard  5336:     }/* end while */
1.224     brouard  5337: 
1.227     brouard  5338:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5339:     /* After last pass */
1.224     brouard  5340: /* Treating death states */
1.214     brouard  5341:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5342:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5343:       /* } */
1.126     brouard  5344:       mi++;    /* Death is another wave */
                   5345:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5346:       /* Only death is a correct wave */
1.126     brouard  5347:       mw[mi][i]=m;
1.257     brouard  5348:     } /* else not in a death state */
1.224     brouard  5349: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5350:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5351:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.309     brouard  5352:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* month of death occured before last wave month and status should have been death instead of -1 */
1.227     brouard  5353:          nbwarn++;
                   5354:          if(firstfiv==0){
1.309     brouard  5355:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5356:            firstfiv=1;
                   5357:          }else{
1.309     brouard  5358:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5359:          }
1.309     brouard  5360:            s[m][i]=nlstate+1; /* Fixing the status as death. Be careful if multiple death states */
                   5361:        }else{ /* Month of Death occured afer last wave month, potential bias */
1.227     brouard  5362:          nberr++;
                   5363:          if(firstwo==0){
1.309     brouard  5364:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5365:            firstwo=1;
                   5366:          }
1.309     brouard  5367:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5368:        }
1.257     brouard  5369:       }else{ /* if date of interview is unknown */
1.227     brouard  5370:        /* death is known but not confirmed by death status at any wave */
                   5371:        if(firstfour==0){
1.309     brouard  5372:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5373:          firstfour=1;
                   5374:        }
1.309     brouard  5375:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d  with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.214     brouard  5376:       }
1.224     brouard  5377:     } /* end if date of death is known */
                   5378: #endif
1.309     brouard  5379:     wav[i]=mi; /* mi should be the last effective wave (or mli),  */
                   5380:     /* wav[i]=mw[mi][i];   */
1.126     brouard  5381:     if(mi==0){
                   5382:       nbwarn++;
                   5383:       if(first==0){
1.227     brouard  5384:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5385:        first=1;
1.126     brouard  5386:       }
                   5387:       if(first==1){
1.227     brouard  5388:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5389:       }
                   5390:     } /* end mi==0 */
                   5391:   } /* End individuals */
1.214     brouard  5392:   /* wav and mw are no more changed */
1.223     brouard  5393:        
1.214     brouard  5394:   
1.126     brouard  5395:   for(i=1; i<=imx; i++){
                   5396:     for(mi=1; mi<wav[i];mi++){
                   5397:       if (stepm <=0)
1.227     brouard  5398:        dh[mi][i]=1;
1.126     brouard  5399:       else{
1.260     brouard  5400:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5401:          if (agedc[i] < 2*AGESUP) {
                   5402:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5403:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5404:            else if(j<0){
                   5405:              nberr++;
                   5406:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5407:              j=1; /* Temporary Dangerous patch */
                   5408:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5409:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5410:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5411:            }
                   5412:            k=k+1;
                   5413:            if (j >= jmax){
                   5414:              jmax=j;
                   5415:              ijmax=i;
                   5416:            }
                   5417:            if (j <= jmin){
                   5418:              jmin=j;
                   5419:              ijmin=i;
                   5420:            }
                   5421:            sum=sum+j;
                   5422:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5423:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5424:          }
                   5425:        }
                   5426:        else{
                   5427:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5428: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5429:                                        
1.227     brouard  5430:          k=k+1;
                   5431:          if (j >= jmax) {
                   5432:            jmax=j;
                   5433:            ijmax=i;
                   5434:          }
                   5435:          else if (j <= jmin){
                   5436:            jmin=j;
                   5437:            ijmin=i;
                   5438:          }
                   5439:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5440:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5441:          if(j<0){
                   5442:            nberr++;
                   5443:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5444:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5445:          }
                   5446:          sum=sum+j;
                   5447:        }
                   5448:        jk= j/stepm;
                   5449:        jl= j -jk*stepm;
                   5450:        ju= j -(jk+1)*stepm;
                   5451:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5452:          if(jl==0){
                   5453:            dh[mi][i]=jk;
                   5454:            bh[mi][i]=0;
                   5455:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5456:                  * to avoid the price of an extra matrix product in likelihood */
                   5457:            dh[mi][i]=jk+1;
                   5458:            bh[mi][i]=ju;
                   5459:          }
                   5460:        }else{
                   5461:          if(jl <= -ju){
                   5462:            dh[mi][i]=jk;
                   5463:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5464:                                 * is higher than the multiple of stepm and negative otherwise.
                   5465:                                 */
                   5466:          }
                   5467:          else{
                   5468:            dh[mi][i]=jk+1;
                   5469:            bh[mi][i]=ju;
                   5470:          }
                   5471:          if(dh[mi][i]==0){
                   5472:            dh[mi][i]=1; /* At least one step */
                   5473:            bh[mi][i]=ju; /* At least one step */
                   5474:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5475:          }
                   5476:        } /* end if mle */
1.126     brouard  5477:       }
                   5478:     } /* end wave */
                   5479:   }
                   5480:   jmean=sum/k;
                   5481:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5482:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5483: }
1.126     brouard  5484: 
                   5485: /*********** Tricode ****************************/
1.220     brouard  5486:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5487:  {
                   5488:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5489:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5490:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5491:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5492:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5493:     */
1.130     brouard  5494: 
1.242     brouard  5495:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5496:    int modmaxcovj=0; /* Modality max of covariates j */
                   5497:    int cptcode=0; /* Modality max of covariates j */
                   5498:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5499: 
                   5500: 
1.242     brouard  5501:    /* cptcoveff=0;  */
                   5502:    /* *cptcov=0; */
1.126     brouard  5503:  
1.242     brouard  5504:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5505:    for (k=1; k <= maxncov; k++)
                   5506:      for(j=1; j<=2; j++)
                   5507:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5508: 
1.242     brouard  5509:    /* Loop on covariates without age and products and no quantitative variable */
                   5510:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5511:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5512:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5513:        switch(Fixed[k]) {
                   5514:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
1.311     brouard  5515:         modmaxcovj=0;
                   5516:         modmincovj=0;
1.242     brouard  5517:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5518:           ij=(int)(covar[Tvar[k]][i]);
                   5519:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5520:            * If product of Vn*Vm, still boolean *:
                   5521:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5522:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5523:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5524:              modality of the nth covariate of individual i. */
                   5525:           if (ij > modmaxcovj)
                   5526:             modmaxcovj=ij; 
                   5527:           else if (ij < modmincovj) 
                   5528:             modmincovj=ij; 
1.287     brouard  5529:           if (ij <0 || ij >1 ){
1.311     brouard  5530:             printf("ERROR, IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5531:             fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5532:             fflush(ficlog);
                   5533:             exit(1);
1.287     brouard  5534:           }
                   5535:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5536:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5537:             exit(1);
                   5538:           }else
                   5539:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5540:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5541:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5542:           /* getting the maximum value of the modality of the covariate
                   5543:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5544:              female ies 1, then modmaxcovj=1.
                   5545:           */
                   5546:         } /* end for loop on individuals i */
                   5547:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5548:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5549:         cptcode=modmaxcovj;
                   5550:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5551:         /*for (i=0; i<=cptcode; i++) {*/
                   5552:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5553:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5554:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5555:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5556:             if( j != -1){
                   5557:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5558:                                  covariate for which somebody answered excluding 
                   5559:                                  undefined. Usually 2: 0 and 1. */
                   5560:             }
                   5561:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5562:                                     covariate for which somebody answered including 
                   5563:                                     undefined. Usually 3: -1, 0 and 1. */
                   5564:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5565:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5566:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5567:                        
1.242     brouard  5568:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5569:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5570:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5571:         /* modmincovj=3; modmaxcovj = 7; */
                   5572:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5573:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5574:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5575:         /* nbcode[Tvar[j]][ij]=k; */
                   5576:         /* nbcode[Tvar[j]][1]=0; */
                   5577:         /* nbcode[Tvar[j]][2]=1; */
                   5578:         /* nbcode[Tvar[j]][3]=2; */
                   5579:         /* To be continued (not working yet). */
                   5580:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5581: 
                   5582:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5583:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5584:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5585:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5586:         /*, could be restored in the future */
                   5587:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5588:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5589:             break;
                   5590:           }
                   5591:           ij++;
1.287     brouard  5592:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5593:           cptcode = ij; /* New max modality for covar j */
                   5594:         } /* end of loop on modality i=-1 to 1 or more */
                   5595:         break;
                   5596:        case 1: /* Testing on varying covariate, could be simple and
                   5597:                * should look at waves or product of fixed *
                   5598:                * varying. No time to test -1, assuming 0 and 1 only */
                   5599:         ij=0;
                   5600:         for(i=0; i<=1;i++){
                   5601:           nbcode[Tvar[k]][++ij]=i;
                   5602:         }
                   5603:         break;
                   5604:        default:
                   5605:         break;
                   5606:        } /* end switch */
                   5607:      } /* end dummy test */
1.311     brouard  5608:      if(Dummy[k]==1 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5609:        for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5610:         if(isnan(covar[Tvar[k]][i])){
                   5611:           printf("ERROR, IMaCh doesn't treat fixed quantitative covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5612:           fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5613:           fflush(ficlog);
                   5614:           exit(1);
                   5615:          }
                   5616:        }
                   5617:      }
1.287     brouard  5618:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5619:   
                   5620:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5621:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5622:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5623:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5624:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5625:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5626:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5627:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5628:   
                   5629:    ij=0;
                   5630:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5631:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5632:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5633:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5634:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5635:        /* If product not in single variable we don't print results */
                   5636:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5637:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5638:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5639:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5640:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5641:        if(Fixed[k]!=0)
                   5642:         anyvaryingduminmodel=1;
                   5643:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5644:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5645:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5646:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5647:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5648:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5649:      } 
                   5650:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5651:    /* ij--; */
                   5652:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5653:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5654:                * because they can be excluded from the model and real
                   5655:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5656:    for(j=ij+1; j<= cptcovt; j++){
                   5657:      Tvaraff[j]=0;
                   5658:      Tmodelind[j]=0;
                   5659:    }
                   5660:    for(j=ntveff+1; j<= cptcovt; j++){
                   5661:      TmodelInvind[j]=0;
                   5662:    }
                   5663:    /* To be sorted */
                   5664:    ;
                   5665:  }
1.126     brouard  5666: 
1.145     brouard  5667: 
1.126     brouard  5668: /*********** Health Expectancies ****************/
                   5669: 
1.235     brouard  5670:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5671: 
                   5672: {
                   5673:   /* Health expectancies, no variances */
1.164     brouard  5674:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5675:   int nhstepma, nstepma; /* Decreasing with age */
                   5676:   double age, agelim, hf;
                   5677:   double ***p3mat;
                   5678:   double eip;
                   5679: 
1.238     brouard  5680:   /* pstamp(ficreseij); */
1.126     brouard  5681:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5682:   fprintf(ficreseij,"# Age");
                   5683:   for(i=1; i<=nlstate;i++){
                   5684:     for(j=1; j<=nlstate;j++){
                   5685:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5686:     }
                   5687:     fprintf(ficreseij," e%1d. ",i);
                   5688:   }
                   5689:   fprintf(ficreseij,"\n");
                   5690: 
                   5691:   
                   5692:   if(estepm < stepm){
                   5693:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5694:   }
                   5695:   else  hstepm=estepm;   
                   5696:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5697:    * This is mainly to measure the difference between two models: for example
                   5698:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5699:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5700:    * progression in between and thus overestimating or underestimating according
                   5701:    * to the curvature of the survival function. If, for the same date, we 
                   5702:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5703:    * to compare the new estimate of Life expectancy with the same linear 
                   5704:    * hypothesis. A more precise result, taking into account a more precise
                   5705:    * curvature will be obtained if estepm is as small as stepm. */
                   5706: 
                   5707:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5708:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5709:      nhstepm is the number of hstepm from age to agelim 
                   5710:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5711:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5712:      and note for a fixed period like estepm months */
                   5713:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5714:      survival function given by stepm (the optimization length). Unfortunately it
                   5715:      means that if the survival funtion is printed only each two years of age and if
                   5716:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5717:      results. So we changed our mind and took the option of the best precision.
                   5718:   */
                   5719:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5720: 
                   5721:   agelim=AGESUP;
                   5722:   /* If stepm=6 months */
                   5723:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5724:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5725:     
                   5726: /* nhstepm age range expressed in number of stepm */
                   5727:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5728:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5729:   /* if (stepm >= YEARM) hstepm=1;*/
                   5730:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5731:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5732: 
                   5733:   for (age=bage; age<=fage; age ++){ 
                   5734:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5735:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5736:     /* if (stepm >= YEARM) hstepm=1;*/
                   5737:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5738: 
                   5739:     /* If stepm=6 months */
                   5740:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5741:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5742:     
1.235     brouard  5743:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5744:     
                   5745:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5746:     
                   5747:     printf("%d|",(int)age);fflush(stdout);
                   5748:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5749:     
                   5750:     /* Computing expectancies */
                   5751:     for(i=1; i<=nlstate;i++)
                   5752:       for(j=1; j<=nlstate;j++)
                   5753:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5754:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5755:          
                   5756:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5757: 
                   5758:        }
                   5759: 
                   5760:     fprintf(ficreseij,"%3.0f",age );
                   5761:     for(i=1; i<=nlstate;i++){
                   5762:       eip=0;
                   5763:       for(j=1; j<=nlstate;j++){
                   5764:        eip +=eij[i][j][(int)age];
                   5765:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5766:       }
                   5767:       fprintf(ficreseij,"%9.4f", eip );
                   5768:     }
                   5769:     fprintf(ficreseij,"\n");
                   5770:     
                   5771:   }
                   5772:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5773:   printf("\n");
                   5774:   fprintf(ficlog,"\n");
                   5775:   
                   5776: }
                   5777: 
1.235     brouard  5778:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5779: 
                   5780: {
                   5781:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5782:      to initial status i, ei. .
1.126     brouard  5783:   */
                   5784:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5785:   int nhstepma, nstepma; /* Decreasing with age */
                   5786:   double age, agelim, hf;
                   5787:   double ***p3matp, ***p3matm, ***varhe;
                   5788:   double **dnewm,**doldm;
                   5789:   double *xp, *xm;
                   5790:   double **gp, **gm;
                   5791:   double ***gradg, ***trgradg;
                   5792:   int theta;
                   5793: 
                   5794:   double eip, vip;
                   5795: 
                   5796:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5797:   xp=vector(1,npar);
                   5798:   xm=vector(1,npar);
                   5799:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5800:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5801:   
                   5802:   pstamp(ficresstdeij);
                   5803:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5804:   fprintf(ficresstdeij,"# Age");
                   5805:   for(i=1; i<=nlstate;i++){
                   5806:     for(j=1; j<=nlstate;j++)
                   5807:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5808:     fprintf(ficresstdeij," e%1d. ",i);
                   5809:   }
                   5810:   fprintf(ficresstdeij,"\n");
                   5811: 
                   5812:   pstamp(ficrescveij);
                   5813:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5814:   fprintf(ficrescveij,"# Age");
                   5815:   for(i=1; i<=nlstate;i++)
                   5816:     for(j=1; j<=nlstate;j++){
                   5817:       cptj= (j-1)*nlstate+i;
                   5818:       for(i2=1; i2<=nlstate;i2++)
                   5819:        for(j2=1; j2<=nlstate;j2++){
                   5820:          cptj2= (j2-1)*nlstate+i2;
                   5821:          if(cptj2 <= cptj)
                   5822:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5823:        }
                   5824:     }
                   5825:   fprintf(ficrescveij,"\n");
                   5826:   
                   5827:   if(estepm < stepm){
                   5828:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5829:   }
                   5830:   else  hstepm=estepm;   
                   5831:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5832:    * This is mainly to measure the difference between two models: for example
                   5833:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5834:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5835:    * progression in between and thus overestimating or underestimating according
                   5836:    * to the curvature of the survival function. If, for the same date, we 
                   5837:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5838:    * to compare the new estimate of Life expectancy with the same linear 
                   5839:    * hypothesis. A more precise result, taking into account a more precise
                   5840:    * curvature will be obtained if estepm is as small as stepm. */
                   5841: 
                   5842:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5843:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5844:      nhstepm is the number of hstepm from age to agelim 
                   5845:      nstepm is the number of stepm from age to agelin. 
                   5846:      Look at hpijx to understand the reason of that which relies in memory size
                   5847:      and note for a fixed period like estepm months */
                   5848:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5849:      survival function given by stepm (the optimization length). Unfortunately it
                   5850:      means that if the survival funtion is printed only each two years of age and if
                   5851:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5852:      results. So we changed our mind and took the option of the best precision.
                   5853:   */
                   5854:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5855: 
                   5856:   /* If stepm=6 months */
                   5857:   /* nhstepm age range expressed in number of stepm */
                   5858:   agelim=AGESUP;
                   5859:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5860:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5861:   /* if (stepm >= YEARM) hstepm=1;*/
                   5862:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5863:   
                   5864:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5865:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5866:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5867:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5868:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5869:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5870: 
                   5871:   for (age=bage; age<=fage; age ++){ 
                   5872:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5873:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5874:     /* if (stepm >= YEARM) hstepm=1;*/
                   5875:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5876:                
1.126     brouard  5877:     /* If stepm=6 months */
                   5878:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5879:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5880:     
                   5881:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5882:                
1.126     brouard  5883:     /* Computing  Variances of health expectancies */
                   5884:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5885:        decrease memory allocation */
                   5886:     for(theta=1; theta <=npar; theta++){
                   5887:       for(i=1; i<=npar; i++){ 
1.222     brouard  5888:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5889:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5890:       }
1.235     brouard  5891:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5892:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5893:                        
1.126     brouard  5894:       for(j=1; j<= nlstate; j++){
1.222     brouard  5895:        for(i=1; i<=nlstate; i++){
                   5896:          for(h=0; h<=nhstepm-1; h++){
                   5897:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5898:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5899:          }
                   5900:        }
1.126     brouard  5901:       }
1.218     brouard  5902:                        
1.126     brouard  5903:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5904:        for(h=0; h<=nhstepm-1; h++){
                   5905:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5906:        }
1.126     brouard  5907:     }/* End theta */
                   5908:     
                   5909:     
                   5910:     for(h=0; h<=nhstepm-1; h++)
                   5911:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5912:        for(theta=1; theta <=npar; theta++)
                   5913:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5914:     
1.218     brouard  5915:                
1.222     brouard  5916:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5917:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5918:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5919:                
1.222     brouard  5920:     printf("%d|",(int)age);fflush(stdout);
                   5921:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5922:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5923:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5924:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5925:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5926:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5927:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5928:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5929:       }
                   5930:     }
1.218     brouard  5931:                
1.126     brouard  5932:     /* Computing expectancies */
1.235     brouard  5933:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5934:     for(i=1; i<=nlstate;i++)
                   5935:       for(j=1; j<=nlstate;j++)
1.222     brouard  5936:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5937:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5938:                                        
1.222     brouard  5939:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5940:                                        
1.222     brouard  5941:        }
1.269     brouard  5942: 
                   5943:     /* Standard deviation of expectancies ij */                
1.126     brouard  5944:     fprintf(ficresstdeij,"%3.0f",age );
                   5945:     for(i=1; i<=nlstate;i++){
                   5946:       eip=0.;
                   5947:       vip=0.;
                   5948:       for(j=1; j<=nlstate;j++){
1.222     brouard  5949:        eip += eij[i][j][(int)age];
                   5950:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5951:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5952:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5953:       }
                   5954:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5955:     }
                   5956:     fprintf(ficresstdeij,"\n");
1.218     brouard  5957:                
1.269     brouard  5958:     /* Variance of expectancies ij */          
1.126     brouard  5959:     fprintf(ficrescveij,"%3.0f",age );
                   5960:     for(i=1; i<=nlstate;i++)
                   5961:       for(j=1; j<=nlstate;j++){
1.222     brouard  5962:        cptj= (j-1)*nlstate+i;
                   5963:        for(i2=1; i2<=nlstate;i2++)
                   5964:          for(j2=1; j2<=nlstate;j2++){
                   5965:            cptj2= (j2-1)*nlstate+i2;
                   5966:            if(cptj2 <= cptj)
                   5967:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5968:          }
1.126     brouard  5969:       }
                   5970:     fprintf(ficrescveij,"\n");
1.218     brouard  5971:                
1.126     brouard  5972:   }
                   5973:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5974:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5975:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5976:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5977:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5978:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5979:   printf("\n");
                   5980:   fprintf(ficlog,"\n");
1.218     brouard  5981:        
1.126     brouard  5982:   free_vector(xm,1,npar);
                   5983:   free_vector(xp,1,npar);
                   5984:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5985:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5986:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5987: }
1.218     brouard  5988:  
1.126     brouard  5989: /************ Variance ******************/
1.235     brouard  5990:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5991:  {
1.279     brouard  5992:    /** Variance of health expectancies 
                   5993:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5994:     * double **newm;
                   5995:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5996:     */
1.218     brouard  5997:   
                   5998:    /* int movingaverage(); */
                   5999:    double **dnewm,**doldm;
                   6000:    double **dnewmp,**doldmp;
                   6001:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  6002:    int first=0;
1.218     brouard  6003:    int k;
                   6004:    double *xp;
1.279     brouard  6005:    double **gp, **gm;  /**< for var eij */
                   6006:    double ***gradg, ***trgradg; /**< for var eij */
                   6007:    double **gradgp, **trgradgp; /**< for var p point j */
                   6008:    double *gpp, *gmp; /**< for var p point j */
                   6009:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  6010:    double ***p3mat;
                   6011:    double age,agelim, hf;
                   6012:    /* double ***mobaverage; */
                   6013:    int theta;
                   6014:    char digit[4];
                   6015:    char digitp[25];
                   6016: 
                   6017:    char fileresprobmorprev[FILENAMELENGTH];
                   6018: 
                   6019:    if(popbased==1){
                   6020:      if(mobilav!=0)
                   6021:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   6022:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   6023:    }
                   6024:    else 
                   6025:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  6026: 
1.218     brouard  6027:    /* if (mobilav!=0) { */
                   6028:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6029:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   6030:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   6031:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   6032:    /*   } */
                   6033:    /* } */
                   6034: 
                   6035:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   6036:    sprintf(digit,"%-d",ij);
                   6037:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   6038:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   6039:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   6040:    strcat(fileresprobmorprev,fileresu);
                   6041:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   6042:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   6043:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   6044:    }
                   6045:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6046:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6047:    pstamp(ficresprobmorprev);
                   6048:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  6049:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   6050:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   6051:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   6052:    }
                   6053:    for(j=1;j<=cptcoveff;j++) 
                   6054:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   6055:    fprintf(ficresprobmorprev,"\n");
                   6056: 
1.218     brouard  6057:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   6058:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6059:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   6060:      for(i=1; i<=nlstate;i++)
                   6061:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   6062:    }  
                   6063:    fprintf(ficresprobmorprev,"\n");
                   6064:   
                   6065:    fprintf(ficgp,"\n# Routine varevsij");
                   6066:    fprintf(ficgp,"\nunset title \n");
                   6067:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   6068:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   6069:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  6070: 
1.218     brouard  6071:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6072:    pstamp(ficresvij);
                   6073:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   6074:    if(popbased==1)
                   6075:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   6076:    else
                   6077:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   6078:    fprintf(ficresvij,"# Age");
                   6079:    for(i=1; i<=nlstate;i++)
                   6080:      for(j=1; j<=nlstate;j++)
                   6081:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   6082:    fprintf(ficresvij,"\n");
                   6083: 
                   6084:    xp=vector(1,npar);
                   6085:    dnewm=matrix(1,nlstate,1,npar);
                   6086:    doldm=matrix(1,nlstate,1,nlstate);
                   6087:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   6088:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6089: 
                   6090:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   6091:    gpp=vector(nlstate+1,nlstate+ndeath);
                   6092:    gmp=vector(nlstate+1,nlstate+ndeath);
                   6093:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  6094:   
1.218     brouard  6095:    if(estepm < stepm){
                   6096:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   6097:    }
                   6098:    else  hstepm=estepm;   
                   6099:    /* For example we decided to compute the life expectancy with the smallest unit */
                   6100:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6101:       nhstepm is the number of hstepm from age to agelim 
                   6102:       nstepm is the number of stepm from age to agelim. 
                   6103:       Look at function hpijx to understand why because of memory size limitations, 
                   6104:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   6105:       survival function given by stepm (the optimization length). Unfortunately it
                   6106:       means that if the survival funtion is printed every two years of age and if
                   6107:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6108:       results. So we changed our mind and took the option of the best precision.
                   6109:    */
                   6110:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6111:    agelim = AGESUP;
                   6112:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6113:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6114:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6115:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6116:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   6117:      gp=matrix(0,nhstepm,1,nlstate);
                   6118:      gm=matrix(0,nhstepm,1,nlstate);
                   6119:                
                   6120:                
                   6121:      for(theta=1; theta <=npar; theta++){
                   6122:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   6123:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6124:        }
1.279     brouard  6125:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   6126:        * returns into prlim .
1.288     brouard  6127:        */
1.242     brouard  6128:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  6129: 
                   6130:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  6131:        if (popbased==1) {
                   6132:         if(mobilav ==0){
                   6133:           for(i=1; i<=nlstate;i++)
                   6134:             prlim[i][i]=probs[(int)age][i][ij];
                   6135:         }else{ /* mobilav */ 
                   6136:           for(i=1; i<=nlstate;i++)
                   6137:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6138:         }
                   6139:        }
1.295     brouard  6140:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}x\f$ at horizon h.
1.279     brouard  6141:        */                      
                   6142:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
1.292     brouard  6143:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}x\f$, which are the probability
1.279     brouard  6144:        * at horizon h in state j including mortality.
                   6145:        */
1.218     brouard  6146:        for(j=1; j<= nlstate; j++){
                   6147:         for(h=0; h<=nhstepm; h++){
                   6148:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6149:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6150:         }
                   6151:        }
1.279     brouard  6152:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6153:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6154:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6155:        */
                   6156:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6157:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6158:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6159:        }
                   6160:        
                   6161:        /* Again with minus shift */
1.218     brouard  6162:                        
                   6163:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6164:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6165: 
1.242     brouard  6166:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6167:                        
                   6168:        if (popbased==1) {
                   6169:         if(mobilav ==0){
                   6170:           for(i=1; i<=nlstate;i++)
                   6171:             prlim[i][i]=probs[(int)age][i][ij];
                   6172:         }else{ /* mobilav */ 
                   6173:           for(i=1; i<=nlstate;i++)
                   6174:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6175:         }
                   6176:        }
                   6177:                        
1.235     brouard  6178:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6179:                        
                   6180:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6181:         for(h=0; h<=nhstepm; h++){
                   6182:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6183:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6184:         }
                   6185:        }
                   6186:        /* This for computing probability of death (h=1 means
                   6187:          computed over hstepm matrices product = hstepm*stepm months) 
                   6188:          as a weighted average of prlim.
                   6189:        */
                   6190:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6191:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6192:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6193:        }    
1.279     brouard  6194:        /* end shifting computations */
                   6195: 
                   6196:        /**< Computing gradient matrix at horizon h 
                   6197:        */
1.218     brouard  6198:        for(j=1; j<= nlstate; j++) /* vareij */
                   6199:         for(h=0; h<=nhstepm; h++){
                   6200:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6201:         }
1.279     brouard  6202:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6203:        */
                   6204:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6205:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6206:        }
                   6207:                        
                   6208:      } /* End theta */
1.279     brouard  6209:      
                   6210:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6211:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6212:                
                   6213:      for(h=0; h<=nhstepm; h++) /* veij */
                   6214:        for(j=1; j<=nlstate;j++)
                   6215:         for(theta=1; theta <=npar; theta++)
                   6216:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6217:                
                   6218:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6219:        for(theta=1; theta <=npar; theta++)
                   6220:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6221:      /**< as well as its transposed matrix 
                   6222:       */               
1.218     brouard  6223:                
                   6224:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6225:      for(i=1;i<=nlstate;i++)
                   6226:        for(j=1;j<=nlstate;j++)
                   6227:         vareij[i][j][(int)age] =0.;
1.279     brouard  6228: 
                   6229:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6230:       * and k (nhstepm) formula 15 of article
                   6231:       * Lievre-Brouard-Heathcote
                   6232:       */
                   6233:      
1.218     brouard  6234:      for(h=0;h<=nhstepm;h++){
                   6235:        for(k=0;k<=nhstepm;k++){
                   6236:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6237:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6238:         for(i=1;i<=nlstate;i++)
                   6239:           for(j=1;j<=nlstate;j++)
                   6240:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6241:        }
                   6242:      }
                   6243:                
1.279     brouard  6244:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6245:       * p.j overall mortality formula 49 but computed directly because
                   6246:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6247:       * wix is independent of theta.
                   6248:       */
1.218     brouard  6249:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6250:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6251:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6252:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6253:         varppt[j][i]=doldmp[j][i];
                   6254:      /* end ppptj */
                   6255:      /*  x centered again */
                   6256:                
1.242     brouard  6257:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6258:                
                   6259:      if (popbased==1) {
                   6260:        if(mobilav ==0){
                   6261:         for(i=1; i<=nlstate;i++)
                   6262:           prlim[i][i]=probs[(int)age][i][ij];
                   6263:        }else{ /* mobilav */ 
                   6264:         for(i=1; i<=nlstate;i++)
                   6265:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6266:        }
                   6267:      }
                   6268:                
                   6269:      /* This for computing probability of death (h=1 means
                   6270:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6271:        as a weighted average of prlim.
                   6272:      */
1.235     brouard  6273:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6274:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6275:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6276:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6277:      }    
                   6278:      /* end probability of death */
                   6279:                
                   6280:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6281:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6282:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6283:        for(i=1; i<=nlstate;i++){
                   6284:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6285:        }
                   6286:      } 
                   6287:      fprintf(ficresprobmorprev,"\n");
                   6288:                
                   6289:      fprintf(ficresvij,"%.0f ",age );
                   6290:      for(i=1; i<=nlstate;i++)
                   6291:        for(j=1; j<=nlstate;j++){
                   6292:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6293:        }
                   6294:      fprintf(ficresvij,"\n");
                   6295:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6296:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6297:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6298:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6299:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6300:    } /* End age */
                   6301:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6302:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6303:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6304:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6305:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6306:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6307:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6308:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6309:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6310:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6311:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6312:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6313:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6314:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6315:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6316:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6317:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6318:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6319:     */
1.218     brouard  6320:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6321:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6322: 
1.218     brouard  6323:    free_vector(xp,1,npar);
                   6324:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6325:    free_matrix(dnewm,1,nlstate,1,npar);
                   6326:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6327:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6328:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6329:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6330:    fclose(ficresprobmorprev);
                   6331:    fflush(ficgp);
                   6332:    fflush(fichtm); 
                   6333:  }  /* end varevsij */
1.126     brouard  6334: 
                   6335: /************ Variance of prevlim ******************/
1.269     brouard  6336:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6337: {
1.205     brouard  6338:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6339:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6340: 
1.268     brouard  6341:   double **dnewmpar,**doldm;
1.126     brouard  6342:   int i, j, nhstepm, hstepm;
                   6343:   double *xp;
                   6344:   double *gp, *gm;
                   6345:   double **gradg, **trgradg;
1.208     brouard  6346:   double **mgm, **mgp;
1.126     brouard  6347:   double age,agelim;
                   6348:   int theta;
                   6349:   
                   6350:   pstamp(ficresvpl);
1.288     brouard  6351:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6352:   fprintf(ficresvpl,"# Age ");
                   6353:   if(nresult >=1)
                   6354:     fprintf(ficresvpl," Result# ");
1.126     brouard  6355:   for(i=1; i<=nlstate;i++)
                   6356:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6357:   fprintf(ficresvpl,"\n");
                   6358: 
                   6359:   xp=vector(1,npar);
1.268     brouard  6360:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6361:   doldm=matrix(1,nlstate,1,nlstate);
                   6362:   
                   6363:   hstepm=1*YEARM; /* Every year of age */
                   6364:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6365:   agelim = AGESUP;
                   6366:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6367:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6368:     if (stepm >= YEARM) hstepm=1;
                   6369:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6370:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6371:     mgp=matrix(1,npar,1,nlstate);
                   6372:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6373:     gp=vector(1,nlstate);
                   6374:     gm=vector(1,nlstate);
                   6375: 
                   6376:     for(theta=1; theta <=npar; theta++){
                   6377:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6378:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6379:       }
1.288     brouard  6380:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6381:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6382:       /* else */
                   6383:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6384:       for(i=1;i<=nlstate;i++){
1.126     brouard  6385:        gp[i] = prlim[i][i];
1.208     brouard  6386:        mgp[theta][i] = prlim[i][i];
                   6387:       }
1.126     brouard  6388:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6389:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6390:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6391:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6392:       /* else */
                   6393:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6394:       for(i=1;i<=nlstate;i++){
1.126     brouard  6395:        gm[i] = prlim[i][i];
1.208     brouard  6396:        mgm[theta][i] = prlim[i][i];
                   6397:       }
1.126     brouard  6398:       for(i=1;i<=nlstate;i++)
                   6399:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6400:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6401:     } /* End theta */
                   6402: 
                   6403:     trgradg =matrix(1,nlstate,1,npar);
                   6404: 
                   6405:     for(j=1; j<=nlstate;j++)
                   6406:       for(theta=1; theta <=npar; theta++)
                   6407:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6408:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6409:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6410:     /*   for(j=1; j<=nlstate;j++){ */
                   6411:     /*         printf(" %d ",j); */
                   6412:     /*         for(theta=1; theta <=npar; theta++) */
                   6413:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6414:     /*         printf("\n "); */
                   6415:     /*   } */
                   6416:     /* } */
                   6417:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6418:     /*   printf("\n gradg %d ",(int)age); */
                   6419:     /*   for(j=1; j<=nlstate;j++){ */
                   6420:     /*         printf("%d ",j); */
                   6421:     /*         for(theta=1; theta <=npar; theta++) */
                   6422:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6423:     /*         printf("\n "); */
                   6424:     /*   } */
                   6425:     /* } */
1.126     brouard  6426: 
                   6427:     for(i=1;i<=nlstate;i++)
                   6428:       varpl[i][(int)age] =0.;
1.209     brouard  6429:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6430:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6431:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6432:     }else{
1.268     brouard  6433:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6434:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6435:     }
1.126     brouard  6436:     for(i=1;i<=nlstate;i++)
                   6437:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6438: 
                   6439:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6440:     if(nresult >=1)
                   6441:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6442:     for(i=1; i<=nlstate;i++){
1.126     brouard  6443:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6444:       /* for(j=1;j<=nlstate;j++) */
                   6445:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6446:     }
1.126     brouard  6447:     fprintf(ficresvpl,"\n");
                   6448:     free_vector(gp,1,nlstate);
                   6449:     free_vector(gm,1,nlstate);
1.208     brouard  6450:     free_matrix(mgm,1,npar,1,nlstate);
                   6451:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6452:     free_matrix(gradg,1,npar,1,nlstate);
                   6453:     free_matrix(trgradg,1,nlstate,1,npar);
                   6454:   } /* End age */
                   6455: 
                   6456:   free_vector(xp,1,npar);
                   6457:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6458:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6459: 
                   6460: }
                   6461: 
                   6462: 
                   6463: /************ Variance of backprevalence limit ******************/
1.269     brouard  6464:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6465: {
                   6466:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6467:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6468: 
                   6469:   double **dnewmpar,**doldm;
                   6470:   int i, j, nhstepm, hstepm;
                   6471:   double *xp;
                   6472:   double *gp, *gm;
                   6473:   double **gradg, **trgradg;
                   6474:   double **mgm, **mgp;
                   6475:   double age,agelim;
                   6476:   int theta;
                   6477:   
                   6478:   pstamp(ficresvbl);
                   6479:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6480:   fprintf(ficresvbl,"# Age ");
                   6481:   if(nresult >=1)
                   6482:     fprintf(ficresvbl," Result# ");
                   6483:   for(i=1; i<=nlstate;i++)
                   6484:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6485:   fprintf(ficresvbl,"\n");
                   6486: 
                   6487:   xp=vector(1,npar);
                   6488:   dnewmpar=matrix(1,nlstate,1,npar);
                   6489:   doldm=matrix(1,nlstate,1,nlstate);
                   6490:   
                   6491:   hstepm=1*YEARM; /* Every year of age */
                   6492:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6493:   agelim = AGEINF;
                   6494:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6495:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6496:     if (stepm >= YEARM) hstepm=1;
                   6497:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6498:     gradg=matrix(1,npar,1,nlstate);
                   6499:     mgp=matrix(1,npar,1,nlstate);
                   6500:     mgm=matrix(1,npar,1,nlstate);
                   6501:     gp=vector(1,nlstate);
                   6502:     gm=vector(1,nlstate);
                   6503: 
                   6504:     for(theta=1; theta <=npar; theta++){
                   6505:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6506:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6507:       }
                   6508:       if(mobilavproj > 0 )
                   6509:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6510:       else
                   6511:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6512:       for(i=1;i<=nlstate;i++){
                   6513:        gp[i] = bprlim[i][i];
                   6514:        mgp[theta][i] = bprlim[i][i];
                   6515:       }
                   6516:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6517:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6518:        if(mobilavproj > 0 )
                   6519:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6520:        else
                   6521:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6522:       for(i=1;i<=nlstate;i++){
                   6523:        gm[i] = bprlim[i][i];
                   6524:        mgm[theta][i] = bprlim[i][i];
                   6525:       }
                   6526:       for(i=1;i<=nlstate;i++)
                   6527:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6528:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6529:     } /* End theta */
                   6530: 
                   6531:     trgradg =matrix(1,nlstate,1,npar);
                   6532: 
                   6533:     for(j=1; j<=nlstate;j++)
                   6534:       for(theta=1; theta <=npar; theta++)
                   6535:        trgradg[j][theta]=gradg[theta][j];
                   6536:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6537:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6538:     /*   for(j=1; j<=nlstate;j++){ */
                   6539:     /*         printf(" %d ",j); */
                   6540:     /*         for(theta=1; theta <=npar; theta++) */
                   6541:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6542:     /*         printf("\n "); */
                   6543:     /*   } */
                   6544:     /* } */
                   6545:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6546:     /*   printf("\n gradg %d ",(int)age); */
                   6547:     /*   for(j=1; j<=nlstate;j++){ */
                   6548:     /*         printf("%d ",j); */
                   6549:     /*         for(theta=1; theta <=npar; theta++) */
                   6550:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6551:     /*         printf("\n "); */
                   6552:     /*   } */
                   6553:     /* } */
                   6554: 
                   6555:     for(i=1;i<=nlstate;i++)
                   6556:       varbpl[i][(int)age] =0.;
                   6557:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6558:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6559:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6560:     }else{
                   6561:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6562:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6563:     }
                   6564:     for(i=1;i<=nlstate;i++)
                   6565:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6566: 
                   6567:     fprintf(ficresvbl,"%.0f ",age );
                   6568:     if(nresult >=1)
                   6569:       fprintf(ficresvbl,"%d ",nres );
                   6570:     for(i=1; i<=nlstate;i++)
                   6571:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6572:     fprintf(ficresvbl,"\n");
                   6573:     free_vector(gp,1,nlstate);
                   6574:     free_vector(gm,1,nlstate);
                   6575:     free_matrix(mgm,1,npar,1,nlstate);
                   6576:     free_matrix(mgp,1,npar,1,nlstate);
                   6577:     free_matrix(gradg,1,npar,1,nlstate);
                   6578:     free_matrix(trgradg,1,nlstate,1,npar);
                   6579:   } /* End age */
                   6580: 
                   6581:   free_vector(xp,1,npar);
                   6582:   free_matrix(doldm,1,nlstate,1,npar);
                   6583:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6584: 
                   6585: }
                   6586: 
                   6587: /************ Variance of one-step probabilities  ******************/
                   6588: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6589:  {
                   6590:    int i, j=0,  k1, l1, tj;
                   6591:    int k2, l2, j1,  z1;
                   6592:    int k=0, l;
                   6593:    int first=1, first1, first2;
                   6594:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6595:    double **dnewm,**doldm;
                   6596:    double *xp;
                   6597:    double *gp, *gm;
                   6598:    double **gradg, **trgradg;
                   6599:    double **mu;
                   6600:    double age, cov[NCOVMAX+1];
                   6601:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6602:    int theta;
                   6603:    char fileresprob[FILENAMELENGTH];
                   6604:    char fileresprobcov[FILENAMELENGTH];
                   6605:    char fileresprobcor[FILENAMELENGTH];
                   6606:    double ***varpij;
                   6607: 
                   6608:    strcpy(fileresprob,"PROB_"); 
                   6609:    strcat(fileresprob,fileres);
                   6610:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6611:      printf("Problem with resultfile: %s\n", fileresprob);
                   6612:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6613:    }
                   6614:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6615:    strcat(fileresprobcov,fileresu);
                   6616:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6617:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6618:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6619:    }
                   6620:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6621:    strcat(fileresprobcor,fileresu);
                   6622:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6623:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6624:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6625:    }
                   6626:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6627:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6628:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6629:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6630:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6631:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6632:    pstamp(ficresprob);
                   6633:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6634:    fprintf(ficresprob,"# Age");
                   6635:    pstamp(ficresprobcov);
                   6636:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6637:    fprintf(ficresprobcov,"# Age");
                   6638:    pstamp(ficresprobcor);
                   6639:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6640:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6641: 
                   6642: 
1.222     brouard  6643:    for(i=1; i<=nlstate;i++)
                   6644:      for(j=1; j<=(nlstate+ndeath);j++){
                   6645:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6646:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6647:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6648:      }  
                   6649:    /* fprintf(ficresprob,"\n");
                   6650:       fprintf(ficresprobcov,"\n");
                   6651:       fprintf(ficresprobcor,"\n");
                   6652:    */
                   6653:    xp=vector(1,npar);
                   6654:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6655:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6656:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6657:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6658:    first=1;
                   6659:    fprintf(ficgp,"\n# Routine varprob");
                   6660:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6661:    fprintf(fichtm,"\n");
                   6662: 
1.288     brouard  6663:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6664:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6665:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6666: and drawn. It helps understanding how is the covariance between two incidences.\
                   6667:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6668:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6669: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6670: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6671: standard deviations wide on each axis. <br>\
                   6672:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6673:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6674: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6675: 
1.222     brouard  6676:    cov[1]=1;
                   6677:    /* tj=cptcoveff; */
1.225     brouard  6678:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6679:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6680:    j1=0;
1.224     brouard  6681:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6682:      if  (cptcovn>0) {
                   6683:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6684:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6685:        fprintf(ficresprob, "**********\n#\n");
                   6686:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6687:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6688:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6689:                        
1.222     brouard  6690:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6691:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6692:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6693:                        
                   6694:                        
1.222     brouard  6695:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6696:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6697:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6698:                        
1.222     brouard  6699:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6700:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6701:        fprintf(ficresprobcor, "**********\n#");    
                   6702:        if(invalidvarcomb[j1]){
                   6703:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6704:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6705:         continue;
                   6706:        }
                   6707:      }
                   6708:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6709:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6710:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6711:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6712:      for (age=bage; age<=fage; age ++){ 
                   6713:        cov[2]=age;
                   6714:        if(nagesqr==1)
                   6715:         cov[3]= age*age;
                   6716:        for (k=1; k<=cptcovn;k++) {
                   6717:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6718:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6719:                                                                    * 1  1 1 1 1
                   6720:                                                                    * 2  2 1 1 1
                   6721:                                                                    * 3  1 2 1 1
                   6722:                                                                    */
                   6723:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6724:        }
                   6725:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6726:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6727:        for (k=1; k<=cptcovprod;k++)
                   6728:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6729:                        
                   6730:                        
1.222     brouard  6731:        for(theta=1; theta <=npar; theta++){
                   6732:         for(i=1; i<=npar; i++)
                   6733:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6734:                                
1.222     brouard  6735:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6736:                                
1.222     brouard  6737:         k=0;
                   6738:         for(i=1; i<= (nlstate); i++){
                   6739:           for(j=1; j<=(nlstate+ndeath);j++){
                   6740:             k=k+1;
                   6741:             gp[k]=pmmij[i][j];
                   6742:           }
                   6743:         }
1.220     brouard  6744:                                
1.222     brouard  6745:         for(i=1; i<=npar; i++)
                   6746:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6747:                                
1.222     brouard  6748:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6749:         k=0;
                   6750:         for(i=1; i<=(nlstate); i++){
                   6751:           for(j=1; j<=(nlstate+ndeath);j++){
                   6752:             k=k+1;
                   6753:             gm[k]=pmmij[i][j];
                   6754:           }
                   6755:         }
1.220     brouard  6756:                                
1.222     brouard  6757:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6758:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6759:        }
1.126     brouard  6760: 
1.222     brouard  6761:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6762:         for(theta=1; theta <=npar; theta++)
                   6763:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6764:                        
1.222     brouard  6765:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6766:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6767:                        
1.222     brouard  6768:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6769:                        
1.222     brouard  6770:        k=0;
                   6771:        for(i=1; i<=(nlstate); i++){
                   6772:         for(j=1; j<=(nlstate+ndeath);j++){
                   6773:           k=k+1;
                   6774:           mu[k][(int) age]=pmmij[i][j];
                   6775:         }
                   6776:        }
                   6777:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6778:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6779:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6780:                        
1.222     brouard  6781:        /*printf("\n%d ",(int)age);
                   6782:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6783:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6784:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6785:         }*/
1.220     brouard  6786:                        
1.222     brouard  6787:        fprintf(ficresprob,"\n%d ",(int)age);
                   6788:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6789:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6790:                        
1.222     brouard  6791:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6792:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6793:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6794:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6795:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6796:        }
                   6797:        i=0;
                   6798:        for (k=1; k<=(nlstate);k++){
                   6799:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6800:           i++;
                   6801:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6802:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6803:           for (j=1; j<=i;j++){
                   6804:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6805:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6806:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6807:           }
                   6808:         }
                   6809:        }/* end of loop for state */
                   6810:      } /* end of loop for age */
                   6811:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6812:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6813:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6814:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6815:     
                   6816:      /* Confidence intervalle of pij  */
                   6817:      /*
                   6818:        fprintf(ficgp,"\nunset parametric;unset label");
                   6819:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6820:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6821:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6822:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6823:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6824:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6825:      */
                   6826:                
                   6827:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6828:      first1=1;first2=2;
                   6829:      for (k2=1; k2<=(nlstate);k2++){
                   6830:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6831:         if(l2==k2) continue;
                   6832:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6833:         for (k1=1; k1<=(nlstate);k1++){
                   6834:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6835:             if(l1==k1) continue;
                   6836:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6837:             if(i<=j) continue;
                   6838:             for (age=bage; age<=fage; age ++){ 
                   6839:               if ((int)age %5==0){
                   6840:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6841:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6842:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6843:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6844:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6845:                 c12=cv12/sqrt(v1*v2);
                   6846:                 /* Computing eigen value of matrix of covariance */
                   6847:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6848:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6849:                 if ((lc2 <0) || (lc1 <0) ){
                   6850:                   if(first2==1){
                   6851:                     first1=0;
                   6852:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6853:                   }
                   6854:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6855:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6856:                   /* lc2=fabs(lc2); */
                   6857:                 }
1.220     brouard  6858:                                                                
1.222     brouard  6859:                 /* Eigen vectors */
1.280     brouard  6860:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6861:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6862:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6863:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6864:                 }else
                   6865:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6866:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6867:                 v21=(lc1-v1)/cv12*v11;
                   6868:                 v12=-v21;
                   6869:                 v22=v11;
                   6870:                 tnalp=v21/v11;
                   6871:                 if(first1==1){
                   6872:                   first1=0;
                   6873:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6874:                 }
                   6875:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6876:                 /*printf(fignu*/
                   6877:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6878:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6879:                 if(first==1){
                   6880:                   first=0;
                   6881:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6882:                   fprintf(ficgp,"\nset parametric;unset label");
                   6883:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6884:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6885:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6886:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6887: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6888:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6889:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6890:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6891:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6892:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6893:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6894:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6895:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6896:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6897:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6898:                 }else{
                   6899:                   first=0;
                   6900:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6901:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6902:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6903:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6904:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6905:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6906:                 }/* if first */
                   6907:               } /* age mod 5 */
                   6908:             } /* end loop age */
                   6909:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6910:             first=1;
                   6911:           } /*l12 */
                   6912:         } /* k12 */
                   6913:        } /*l1 */
                   6914:      }/* k1 */
                   6915:    }  /* loop on combination of covariates j1 */
                   6916:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6917:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6918:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6919:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6920:    free_vector(xp,1,npar);
                   6921:    fclose(ficresprob);
                   6922:    fclose(ficresprobcov);
                   6923:    fclose(ficresprobcor);
                   6924:    fflush(ficgp);
                   6925:    fflush(fichtmcov);
                   6926:  }
1.126     brouard  6927: 
                   6928: 
                   6929: /******************* Printing html file ***********/
1.201     brouard  6930: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6931:                  int lastpass, int stepm, int weightopt, char model[],\
                   6932:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.296     brouard  6933:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int prevbcast, int estepm , \
                   6934:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateprojd, double dateback1, \
                   6935:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateprojf, double dateback2){
1.237     brouard  6936:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6937: 
                   6938:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6939:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6940: </ul>");
1.237     brouard  6941:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6942: </ul>", model);
1.214     brouard  6943:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6944:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6945:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6946:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6947:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6948:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6949:    fprintf(fichtm,"\
                   6950:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6951:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6952:    fprintf(fichtm,"\
1.217     brouard  6953:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6954:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6955:    fprintf(fichtm,"\
1.288     brouard  6956:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6957:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6958:    fprintf(fichtm,"\
1.288     brouard  6959:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  6960:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6961:    fprintf(fichtm,"\
1.211     brouard  6962:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6963:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6964:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6965:    if(prevfcast==1){
                   6966:      fprintf(fichtm,"\
                   6967:  - Prevalence projections by age and states:                           \
1.201     brouard  6968:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6969:    }
1.126     brouard  6970: 
                   6971: 
1.225     brouard  6972:    m=pow(2,cptcoveff);
1.222     brouard  6973:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6974: 
1.264     brouard  6975:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6976: 
                   6977:    jj1=0;
                   6978: 
                   6979:    fprintf(fichtm," \n<ul>");
                   6980:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6981:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6982:      if(m != 1 && TKresult[nres]!= k1)
                   6983:        continue;
                   6984:      jj1++;
                   6985:      if (cptcovn > 0) {
                   6986:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6987:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6988:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6989:        }
                   6990:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6991:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6992:        }
                   6993:        fprintf(fichtm,"\">");
                   6994:        
                   6995:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6996:        fprintf(fichtm,"************ Results for covariates");
                   6997:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6998:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6999:        }
                   7000:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7001:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7002:        }
                   7003:        if(invalidvarcomb[k1]){
                   7004:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   7005:         continue;
                   7006:        }
                   7007:        fprintf(fichtm,"</a></li>");
                   7008:      } /* cptcovn >0 */
                   7009:    }
                   7010:      fprintf(fichtm," \n</ul>");
                   7011: 
1.222     brouard  7012:    jj1=0;
1.237     brouard  7013: 
                   7014:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  7015:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  7016:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7017:        continue;
1.220     brouard  7018: 
1.222     brouard  7019:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7020:      jj1++;
                   7021:      if (cptcovn > 0) {
1.264     brouard  7022:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   7023:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7024:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7025:        }
                   7026:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7027:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7028:        }
                   7029:        fprintf(fichtm,"\"</a>");
                   7030:  
1.222     brouard  7031:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7032:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  7033:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7034:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   7035:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7036:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  7037:        }
1.237     brouard  7038:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7039:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7040:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   7041:       }
                   7042:        
1.230     brouard  7043:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  7044:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   7045:        if(invalidvarcomb[k1]){
                   7046:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   7047:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   7048:         continue;
                   7049:        }
                   7050:      }
                   7051:      /* aij, bij */
1.259     brouard  7052:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  7053: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  7054:      /* Pij */
1.241     brouard  7055:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   7056: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  7057:      /* Quasi-incidences */
                   7058:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  7059:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  7060:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  7061: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   7062: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  7063:      /* Survival functions (period) in state j */
                   7064:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7065:        fprintf(fichtm,"<br>\n- Survival functions in state %d. And probability to be observed in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7066: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  7067:      }
                   7068:      /* State specific survival functions (period) */
                   7069:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7070:        fprintf(fichtm,"<br>\n- Survival functions in state %d and in any other live state (total).\
                   7071:  And probability to be observed in various states (up to %d) being in state %d at different ages.      \
1.283     brouard  7072:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  7073:      }
1.288     brouard  7074:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  7075:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7076:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7077: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  7078:      }
1.296     brouard  7079:      if(prevbcast==1){
1.288     brouard  7080:        /* Backward prevalence in each health state */
1.222     brouard  7081:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7082:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7083: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  7084:        }
1.217     brouard  7085:      }
1.222     brouard  7086:      if(prevfcast==1){
1.288     brouard  7087:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  7088:        for(cpt=1; cpt<=nlstate;cpt++){
1.288     brouard  7089:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.296     brouard  7090: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateprojd, dateprojf, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  7091:        }
                   7092:      }
1.296     brouard  7093:      if(prevbcast==1){
1.268     brouard  7094:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   7095:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  7096:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   7097:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   7098:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   7099: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7100:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  7101:        }
                   7102:      }
1.220     brouard  7103:         
1.222     brouard  7104:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  7105:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   7106: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  7107:      }
                   7108:      /* } /\* end i1 *\/ */
                   7109:    }/* End k1 */
                   7110:    fprintf(fichtm,"</ul>");
1.126     brouard  7111: 
1.222     brouard  7112:    fprintf(fichtm,"\
1.126     brouard  7113: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  7114:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  7115:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  7116: But because parameters are usually highly correlated (a higher incidence of disability \
                   7117: and a higher incidence of recovery can give very close observed transition) it might \
                   7118: be very useful to look not only at linear confidence intervals estimated from the \
                   7119: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   7120: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   7121: covariance matrix of the one-step probabilities. \
                   7122: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  7123: 
1.222     brouard  7124:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   7125:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   7126:    fprintf(fichtm,"\
1.126     brouard  7127:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7128:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  7129: 
1.222     brouard  7130:    fprintf(fichtm,"\
1.126     brouard  7131:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7132:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   7133:    fprintf(fichtm,"\
1.126     brouard  7134:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7135:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7136:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7137:    fprintf(fichtm,"\
1.126     brouard  7138:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7139:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7140:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7141:    fprintf(fichtm,"\
1.288     brouard  7142:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7143:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7144:    fprintf(fichtm,"\
1.128     brouard  7145:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7146:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7147:    fprintf(fichtm,"\
1.288     brouard  7148:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7149:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7150: 
                   7151: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7152: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7153: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7154: /*     <br>",fileres,fileres,fileres,fileres); */
                   7155: /*  else  */
                   7156: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7157:    fflush(fichtm);
                   7158:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  7159: 
1.225     brouard  7160:    m=pow(2,cptcoveff);
1.222     brouard  7161:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7162: 
1.222     brouard  7163:    jj1=0;
1.237     brouard  7164: 
1.241     brouard  7165:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7166:    for(k1=1; k1<=m;k1++){
1.253     brouard  7167:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7168:        continue;
1.222     brouard  7169:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7170:      jj1++;
1.126     brouard  7171:      if (cptcovn > 0) {
                   7172:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7173:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7174:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7175:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7176:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7177:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7178:       }
                   7179: 
1.126     brouard  7180:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7181: 
1.222     brouard  7182:        if(invalidvarcomb[k1]){
                   7183:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7184:         continue;
                   7185:        }
1.126     brouard  7186:      }
                   7187:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7188:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7189: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7190: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7191:      }
                   7192:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7193: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7194: true period expectancies (those weighted with period prevalences are also\
                   7195:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7196:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7197: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7198:      /* } /\* end i1 *\/ */
                   7199:    }/* End k1 */
1.241     brouard  7200:   }/* End nres */
1.222     brouard  7201:    fprintf(fichtm,"</ul>");
                   7202:    fflush(fichtm);
1.126     brouard  7203: }
                   7204: 
                   7205: /******************* Gnuplot file **************/
1.296     brouard  7206: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int prevbcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7207: 
                   7208:   char dirfileres[132],optfileres[132];
1.264     brouard  7209:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7210:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7211:   int lv=0, vlv=0, kl=0;
1.130     brouard  7212:   int ng=0;
1.201     brouard  7213:   int vpopbased;
1.223     brouard  7214:   int ioffset; /* variable offset for columns */
1.270     brouard  7215:   int iyearc=1; /* variable column for year of projection  */
                   7216:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7217:   int nres=0; /* Index of resultline */
1.266     brouard  7218:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7219: 
1.126     brouard  7220: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7221: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7222: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7223: /*   } */
                   7224: 
                   7225:   /*#ifdef windows */
                   7226:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7227:   /*#endif */
1.225     brouard  7228:   m=pow(2,cptcoveff);
1.126     brouard  7229: 
1.274     brouard  7230:   /* diagram of the model */
                   7231:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7232:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7233:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7234:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7235: 
                   7236:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7237:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7238:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7239:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7240:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7241:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7242:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7243: 
1.202     brouard  7244:   /* Contribution to likelihood */
                   7245:   /* Plot the probability implied in the likelihood */
1.223     brouard  7246:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7247:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7248:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7249:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7250: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7251:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7252: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7253:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7254:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7255:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7256:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7257:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7258:   for (i=1; i<= nlstate ; i ++) {
                   7259:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7260:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7261:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7262:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7263:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7264:     }
                   7265:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7266:   }
                   7267:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7268:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7269:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7270:   fprintf(ficgp,"\nset out;unset log\n");
                   7271:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7272: 
1.126     brouard  7273:   strcpy(dirfileres,optionfilefiname);
                   7274:   strcpy(optfileres,"vpl");
1.223     brouard  7275:   /* 1eme*/
1.238     brouard  7276:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7277:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7278:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7279:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7280:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7281:          continue;
                   7282:        /* We are interested in selected combination by the resultline */
1.246     brouard  7283:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7284:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7285:        strcpy(gplotlabel,"(");
1.238     brouard  7286:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7287:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7288:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7289:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7290:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7291:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7292:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7293:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7294:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7295:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7296:        }
                   7297:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7298:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7299:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7300:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7301:        }
                   7302:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7303:        /* printf("\n#\n"); */
1.238     brouard  7304:        fprintf(ficgp,"\n#\n");
                   7305:        if(invalidvarcomb[k1]){
1.260     brouard  7306:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7307:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7308:          continue;
                   7309:        }
1.235     brouard  7310:       
1.241     brouard  7311:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7312:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7313:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7314:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7315:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7316:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7317:       /* k1-1 error should be nres-1*/
1.238     brouard  7318:        for (i=1; i<= nlstate ; i ++) {
                   7319:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7320:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7321:        }
1.288     brouard  7322:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7323:        for (i=1; i<= nlstate ; i ++) {
                   7324:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7325:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7326:        } 
1.260     brouard  7327:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7328:        for (i=1; i<= nlstate ; i ++) {
                   7329:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7330:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7331:        }  
1.265     brouard  7332:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7333:        
                   7334:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7335:         if(cptcoveff ==0){
1.271     brouard  7336:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7337:        }else{
                   7338:          kl=0;
                   7339:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7340:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7341:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7342:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7343:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7344:            vlv= nbcode[Tvaraff[k]][lv];
                   7345:            kl++;
                   7346:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7347:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7348:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7349:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7350:            if(k==cptcoveff){
                   7351:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7352:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7353:            }else{
                   7354:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7355:              kl++;
                   7356:            }
                   7357:          } /* end covariate */
                   7358:        } /* end if no covariate */
                   7359: 
1.296     brouard  7360:        if(prevbcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
1.238     brouard  7361:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7362:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7363:          if(cptcoveff ==0){
1.245     brouard  7364:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7365:          }else{
                   7366:            kl=0;
                   7367:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7368:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7369:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7370:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7371:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7372:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7373:              kl++;
1.238     brouard  7374:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7375:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7376:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7377:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7378:              if(k==cptcoveff){
1.245     brouard  7379:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7380:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7381:              }else{
                   7382:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7383:                kl++;
                   7384:              }
                   7385:            } /* end covariate */
                   7386:          } /* end if no covariate */
1.296     brouard  7387:          if(prevbcast == 1){
1.268     brouard  7388:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7389:            /* k1-1 error should be nres-1*/
                   7390:            for (i=1; i<= nlstate ; i ++) {
                   7391:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7392:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7393:            }
1.271     brouard  7394:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7395:            for (i=1; i<= nlstate ; i ++) {
                   7396:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7397:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7398:            } 
1.276     brouard  7399:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7400:            for (i=1; i<= nlstate ; i ++) {
                   7401:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7402:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7403:            } 
1.274     brouard  7404:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7405:          } /* end if backprojcast */
1.296     brouard  7406:        } /* end if prevbcast */
1.276     brouard  7407:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7408:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7409:       } /* nres */
1.201     brouard  7410:     } /* k1 */
                   7411:   } /* cpt */
1.235     brouard  7412: 
                   7413:   
1.126     brouard  7414:   /*2 eme*/
1.238     brouard  7415:   for (k1=1; k1<= m ; k1 ++){  
                   7416:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7417:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7418:        continue;
                   7419:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7420:       strcpy(gplotlabel,"(");
1.238     brouard  7421:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7422:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7423:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7424:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7425:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7426:        vlv= nbcode[Tvaraff[k]][lv];
                   7427:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7428:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7429:       }
1.237     brouard  7430:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7431:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7432:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7433:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7434:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7435:       }
1.264     brouard  7436:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7437:       fprintf(ficgp,"\n#\n");
1.223     brouard  7438:       if(invalidvarcomb[k1]){
                   7439:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7440:        continue;
                   7441:       }
1.219     brouard  7442:                        
1.241     brouard  7443:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7444:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7445:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7446:        if(vpopbased==0){
1.238     brouard  7447:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7448:        }else
1.238     brouard  7449:          fprintf(ficgp,"\nreplot ");
                   7450:        for (i=1; i<= nlstate+1 ; i ++) {
                   7451:          k=2*i;
1.261     brouard  7452:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7453:          for (j=1; j<= nlstate+1 ; j ++) {
                   7454:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7455:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7456:          }   
                   7457:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7458:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7459:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7460:          for (j=1; j<= nlstate+1 ; j ++) {
                   7461:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7462:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7463:          }   
                   7464:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7465:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7466:          for (j=1; j<= nlstate+1 ; j ++) {
                   7467:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7468:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7469:          }   
                   7470:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7471:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7472:        } /* state */
                   7473:       } /* vpopbased */
1.264     brouard  7474:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7475:     } /* end nres */
                   7476:   } /* k1 end 2 eme*/
                   7477:        
                   7478:        
                   7479:   /*3eme*/
                   7480:   for (k1=1; k1<= m ; k1 ++){
                   7481:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7482:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7483:        continue;
                   7484: 
                   7485:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7486:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7487:        strcpy(gplotlabel,"(");
1.238     brouard  7488:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7489:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7490:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7491:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7492:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7493:          vlv= nbcode[Tvaraff[k]][lv];
                   7494:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7495:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7496:        }
                   7497:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7498:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7499:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7500:        }       
1.264     brouard  7501:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7502:        fprintf(ficgp,"\n#\n");
                   7503:        if(invalidvarcomb[k1]){
                   7504:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7505:          continue;
                   7506:        }
                   7507:                        
                   7508:        /*       k=2+nlstate*(2*cpt-2); */
                   7509:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7510:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7511:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7512:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7513: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7514:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7515:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7516:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7517:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7518:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7519:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7520:                                
1.238     brouard  7521:        */
                   7522:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7523:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7524:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7525:                                
1.238     brouard  7526:        } 
1.261     brouard  7527:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7528:       }
1.264     brouard  7529:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7530:     } /* end nres */
                   7531:   } /* end kl 3eme */
1.126     brouard  7532:   
1.223     brouard  7533:   /* 4eme */
1.201     brouard  7534:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7535:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7536:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7537:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7538:        continue;
1.238     brouard  7539:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7540:        strcpy(gplotlabel,"(");
1.238     brouard  7541:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7542:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7543:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7544:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7545:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7546:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7547:          vlv= nbcode[Tvaraff[k]][lv];
                   7548:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7549:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7550:        }
                   7551:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7552:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7553:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7554:        }       
1.264     brouard  7555:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7556:        fprintf(ficgp,"\n#\n");
                   7557:        if(invalidvarcomb[k1]){
                   7558:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7559:          continue;
1.223     brouard  7560:        }
1.238     brouard  7561:       
1.241     brouard  7562:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7563:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7564:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7565: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7566:        k=3;
                   7567:        for (i=1; i<= nlstate ; i ++){
                   7568:          if(i==1){
                   7569:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7570:          }else{
                   7571:            fprintf(ficgp,", '' ");
                   7572:          }
                   7573:          l=(nlstate+ndeath)*(i-1)+1;
                   7574:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7575:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7576:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7577:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7578:        } /* nlstate */
1.264     brouard  7579:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7580:       } /* end cpt state*/ 
                   7581:     } /* end nres */
                   7582:   } /* end covariate k1 */  
                   7583: 
1.220     brouard  7584: /* 5eme */
1.201     brouard  7585:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7586:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7587:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7588:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7589:        continue;
1.238     brouard  7590:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7591:        strcpy(gplotlabel,"(");
1.238     brouard  7592:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7593:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7594:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7595:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7596:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7597:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7598:          vlv= nbcode[Tvaraff[k]][lv];
                   7599:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7600:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7601:        }
                   7602:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7603:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7604:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7605:        }       
1.264     brouard  7606:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7607:        fprintf(ficgp,"\n#\n");
                   7608:        if(invalidvarcomb[k1]){
                   7609:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7610:          continue;
                   7611:        }
1.227     brouard  7612:       
1.241     brouard  7613:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7614:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7615:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7616: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7617:        k=3;
                   7618:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7619:          if(j==1)
                   7620:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7621:          else
                   7622:            fprintf(ficgp,", '' ");
                   7623:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7624:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7625:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7626:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7627:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7628:        } /* nlstate */
                   7629:        fprintf(ficgp,", '' ");
                   7630:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7631:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7632:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7633:          if(j < nlstate)
                   7634:            fprintf(ficgp,"$%d +",k+l);
                   7635:          else
                   7636:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7637:        }
1.264     brouard  7638:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7639:       } /* end cpt state*/ 
                   7640:     } /* end covariate */  
                   7641:   } /* end nres */
1.227     brouard  7642:   
1.220     brouard  7643: /* 6eme */
1.202     brouard  7644:   /* CV preval stable (period) for each covariate */
1.237     brouard  7645:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7646:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7647:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7648:       continue;
1.255     brouard  7649:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7650:       strcpy(gplotlabel,"(");      
1.288     brouard  7651:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7652:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7653:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7654:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7655:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7656:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7657:        vlv= nbcode[Tvaraff[k]][lv];
                   7658:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7659:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7660:       }
1.237     brouard  7661:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7662:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7663:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7664:       }        
1.264     brouard  7665:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7666:       fprintf(ficgp,"\n#\n");
1.223     brouard  7667:       if(invalidvarcomb[k1]){
1.227     brouard  7668:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7669:        continue;
1.223     brouard  7670:       }
1.227     brouard  7671:       
1.241     brouard  7672:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7673:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7674:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7675: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7676:       k=3; /* Offset */
1.255     brouard  7677:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7678:        if(i==1)
                   7679:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7680:        else
                   7681:          fprintf(ficgp,", '' ");
1.255     brouard  7682:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7683:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7684:        for (j=2; j<= nlstate ; j ++)
                   7685:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7686:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7687:       } /* nlstate */
1.264     brouard  7688:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7689:     } /* end cpt state*/ 
                   7690:   } /* end covariate */  
1.227     brouard  7691:   
                   7692:   
1.220     brouard  7693: /* 7eme */
1.296     brouard  7694:   if(prevbcast == 1){
1.288     brouard  7695:     /* CV backward prevalence  for each covariate */
1.237     brouard  7696:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7697:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7698:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7699:        continue;
1.268     brouard  7700:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7701:        strcpy(gplotlabel,"(");      
1.288     brouard  7702:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7703:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7704:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7705:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7706:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7707:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7708:          vlv= nbcode[Tvaraff[k]][lv];
                   7709:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7710:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7711:        }
1.237     brouard  7712:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7713:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7714:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7715:        }       
1.264     brouard  7716:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7717:        fprintf(ficgp,"\n#\n");
                   7718:        if(invalidvarcomb[k1]){
                   7719:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7720:          continue;
                   7721:        }
                   7722:        
1.241     brouard  7723:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7724:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7725:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7726: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7727:        k=3; /* Offset */
1.268     brouard  7728:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7729:          if(i==1)
                   7730:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7731:          else
                   7732:            fprintf(ficgp,", '' ");
                   7733:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7734:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7735:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7736:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7737:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7738:          /* for (j=2; j<= nlstate ; j ++) */
                   7739:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7740:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7741:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7742:        } /* nlstate */
1.264     brouard  7743:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7744:       } /* end cpt state*/ 
                   7745:     } /* end covariate */  
1.296     brouard  7746:   } /* End if prevbcast */
1.218     brouard  7747:   
1.223     brouard  7748:   /* 8eme */
1.218     brouard  7749:   if(prevfcast==1){
1.288     brouard  7750:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  7751:     
1.237     brouard  7752:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7753:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7754:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7755:        continue;
1.211     brouard  7756:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7757:        strcpy(gplotlabel,"(");      
1.288     brouard  7758:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7759:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7760:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7761:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7762:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7763:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7764:          vlv= nbcode[Tvaraff[k]][lv];
                   7765:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7766:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7767:        }
1.237     brouard  7768:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7769:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7770:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7771:        }       
1.264     brouard  7772:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7773:        fprintf(ficgp,"\n#\n");
                   7774:        if(invalidvarcomb[k1]){
                   7775:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7776:          continue;
                   7777:        }
                   7778:        
                   7779:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7780:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7781:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7782:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7783: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7784: 
                   7785:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7786:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7787:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7788:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7789:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7790:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7791:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7792:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7793:          if(i==istart){
1.227     brouard  7794:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7795:          }else{
                   7796:            fprintf(ficgp,",\\\n '' ");
                   7797:          }
                   7798:          if(cptcoveff ==0){ /* No covariate */
                   7799:            ioffset=2; /* Age is in 2 */
                   7800:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7801:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7802:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7803:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7804:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7805:            if(i==nlstate+1){
1.270     brouard  7806:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7807:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7808:              fprintf(ficgp,",\\\n '' ");
                   7809:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7810:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7811:                     offyear,                           \
1.268     brouard  7812:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7813:            }else
1.227     brouard  7814:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7815:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7816:          }else{ /* more than 2 covariates */
1.270     brouard  7817:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7818:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7819:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7820:            iyearc=ioffset-1;
                   7821:            iagec=ioffset;
1.227     brouard  7822:            fprintf(ficgp," u %d:(",ioffset); 
                   7823:            kl=0;
                   7824:            strcpy(gplotcondition,"(");
                   7825:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7826:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7827:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7828:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7829:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7830:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7831:              kl++;
                   7832:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7833:              kl++;
                   7834:              if(k <cptcoveff && cptcoveff>1)
                   7835:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7836:            }
                   7837:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7838:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7839:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7840:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7841:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7842:            if(i==nlstate+1){
1.270     brouard  7843:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7844:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7845:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7846:              fprintf(ficgp," u %d:(",iagec); 
                   7847:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7848:                      iyearc, iagec, offyear,                           \
                   7849:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7850: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7851:            }else{
                   7852:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7853:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7854:            }
                   7855:          } /* end if covariate */
                   7856:        } /* nlstate */
1.264     brouard  7857:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7858:       } /* end cpt state*/
                   7859:     } /* end covariate */
                   7860:   } /* End if prevfcast */
1.227     brouard  7861:   
1.296     brouard  7862:   if(prevbcast==1){
1.268     brouard  7863:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7864:     
                   7865:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7866:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7867:       if(m != 1 && TKresult[nres]!= k1)
                   7868:        continue;
                   7869:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7870:        strcpy(gplotlabel,"(");      
                   7871:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7872:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7873:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7874:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7875:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7876:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7877:          vlv= nbcode[Tvaraff[k]][lv];
                   7878:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7879:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7880:        }
                   7881:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7882:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7883:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7884:        }       
                   7885:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7886:        fprintf(ficgp,"\n#\n");
                   7887:        if(invalidvarcomb[k1]){
                   7888:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7889:          continue;
                   7890:        }
                   7891:        
                   7892:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7893:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7894:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7895:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7896: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7897: 
                   7898:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7899:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7900:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7901:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7902:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7903:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7904:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7905:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7906:          if(i==istart){
                   7907:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7908:          }else{
                   7909:            fprintf(ficgp,",\\\n '' ");
                   7910:          }
                   7911:          if(cptcoveff ==0){ /* No covariate */
                   7912:            ioffset=2; /* Age is in 2 */
                   7913:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7914:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7915:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7916:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7917:            fprintf(ficgp," u %d:(", ioffset); 
                   7918:            if(i==nlstate+1){
1.270     brouard  7919:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7920:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7921:              fprintf(ficgp,",\\\n '' ");
                   7922:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7923:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7924:                     offbyear,                          \
                   7925:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7926:            }else
                   7927:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7928:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7929:          }else{ /* more than 2 covariates */
1.270     brouard  7930:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7931:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7932:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7933:            iyearc=ioffset-1;
                   7934:            iagec=ioffset;
1.268     brouard  7935:            fprintf(ficgp," u %d:(",ioffset); 
                   7936:            kl=0;
                   7937:            strcpy(gplotcondition,"(");
                   7938:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7939:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7940:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7941:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7942:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7943:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7944:              kl++;
                   7945:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7946:              kl++;
                   7947:              if(k <cptcoveff && cptcoveff>1)
                   7948:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7949:            }
                   7950:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7951:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7952:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7953:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7954:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7955:            if(i==nlstate+1){
1.270     brouard  7956:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7957:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7958:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7959:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7960:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7961:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7962:                      iyearc,iagec,offbyear,                            \
                   7963:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7964: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7965:            }else{
                   7966:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7967:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7968:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7969:            }
                   7970:          } /* end if covariate */
                   7971:        } /* nlstate */
                   7972:        fprintf(ficgp,"\nset out; unset label;\n");
                   7973:       } /* end cpt state*/
                   7974:     } /* end covariate */
1.296     brouard  7975:   } /* End if prevbcast */
1.268     brouard  7976:   
1.227     brouard  7977:   
1.238     brouard  7978:   /* 9eme writing MLE parameters */
                   7979:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7980:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7981:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7982:     for(k=1; k <=(nlstate+ndeath); k++){
                   7983:       if (k != i) {
1.227     brouard  7984:        fprintf(ficgp,"#   current state %d\n",k);
                   7985:        for(j=1; j <=ncovmodel; j++){
                   7986:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7987:          jk++; 
                   7988:        }
                   7989:        fprintf(ficgp,"\n");
1.126     brouard  7990:       }
                   7991:     }
1.223     brouard  7992:   }
1.187     brouard  7993:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7994:   
1.145     brouard  7995:   /*goto avoid;*/
1.238     brouard  7996:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7997:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7998:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7999:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   8000:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   8001:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   8002:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8003:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8004:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8005:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8006:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   8007:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8008:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   8009:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   8010:   fprintf(ficgp,"#\n");
1.223     brouard  8011:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  8012:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  8013:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  8014:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  8015:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   8016:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  8017:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  8018:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  8019:        continue;
1.264     brouard  8020:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   8021:       strcpy(gplotlabel,"(");
1.276     brouard  8022:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  8023:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8024:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8025:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8026:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8027:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8028:        vlv= nbcode[Tvaraff[k]][lv];
                   8029:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   8030:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   8031:       }
1.237     brouard  8032:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8033:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  8034:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  8035:       }        
1.264     brouard  8036:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  8037:       fprintf(ficgp,"\n#\n");
1.264     brouard  8038:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  8039:       fprintf(ficgp,"\nset key outside ");
                   8040:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   8041:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  8042:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   8043:       if (ng==1){
                   8044:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   8045:        fprintf(ficgp,"\nunset log y");
                   8046:       }else if (ng==2){
                   8047:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   8048:        fprintf(ficgp,"\nset log y");
                   8049:       }else if (ng==3){
                   8050:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   8051:        fprintf(ficgp,"\nset log y");
                   8052:       }else
                   8053:        fprintf(ficgp,"\nunset title ");
                   8054:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   8055:       i=1;
                   8056:       for(k2=1; k2<=nlstate; k2++) {
                   8057:        k3=i;
                   8058:        for(k=1; k<=(nlstate+ndeath); k++) {
                   8059:          if (k != k2){
                   8060:            switch( ng) {
                   8061:            case 1:
                   8062:              if(nagesqr==0)
                   8063:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   8064:              else /* nagesqr =1 */
                   8065:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8066:              break;
                   8067:            case 2: /* ng=2 */
                   8068:              if(nagesqr==0)
                   8069:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   8070:              else /* nagesqr =1 */
                   8071:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8072:              break;
                   8073:            case 3:
                   8074:              if(nagesqr==0)
                   8075:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   8076:              else /* nagesqr =1 */
                   8077:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   8078:              break;
                   8079:            }
                   8080:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  8081:            ijp=1; /* product no age */
                   8082:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   8083:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  8084:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  8085:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8086:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   8087:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8088:                    if(DummyV[j]==0){
                   8089:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   8090:                    }else{ /* quantitative */
                   8091:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   8092:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8093:                    }
                   8094:                    ij++;
1.237     brouard  8095:                  }
1.268     brouard  8096:                } 
                   8097:              }else if(cptcovprod >0){
                   8098:                if(j==Tprod[ijp]) { /* */ 
                   8099:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   8100:                  if(ijp <=cptcovprod) { /* Product */
                   8101:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   8102:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   8103:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   8104:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   8105:                      }else{ /* Vn is dummy and Vm is quanti */
                   8106:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   8107:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8108:                      }
                   8109:                    }else{ /* Vn*Vm Vn is quanti */
                   8110:                      if(DummyV[Tvard[ijp][2]]==0){
                   8111:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   8112:                      }else{ /* Both quanti */
                   8113:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8114:                      }
1.237     brouard  8115:                    }
1.268     brouard  8116:                    ijp++;
1.237     brouard  8117:                  }
1.268     brouard  8118:                } /* end Tprod */
1.237     brouard  8119:              } else{  /* simple covariate */
1.264     brouard  8120:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  8121:                if(Dummy[j]==0){
                   8122:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   8123:                }else{ /* quantitative */
                   8124:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  8125:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  8126:                }
1.237     brouard  8127:              } /* end simple */
                   8128:            } /* end j */
1.223     brouard  8129:          }else{
                   8130:            i=i-ncovmodel;
                   8131:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   8132:              fprintf(ficgp," (1.");
                   8133:          }
1.227     brouard  8134:          
1.223     brouard  8135:          if(ng != 1){
                   8136:            fprintf(ficgp,")/(1");
1.227     brouard  8137:            
1.264     brouard  8138:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8139:              if(nagesqr==0)
1.264     brouard  8140:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8141:              else /* nagesqr =1 */
1.264     brouard  8142:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8143:               
1.223     brouard  8144:              ij=1;
                   8145:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8146:                 if(cptcovage >0){ 
                   8147:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8148:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8149:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8150:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8151:                       ij++;
                   8152:                     }
                   8153:                   }
                   8154:                 }else
                   8155:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8156:              }
                   8157:              fprintf(ficgp,")");
                   8158:            }
                   8159:            fprintf(ficgp,")");
                   8160:            if(ng ==2)
1.276     brouard  8161:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8162:            else /* ng= 3 */
1.276     brouard  8163:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8164:          }else{ /* end ng <> 1 */
                   8165:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8166:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8167:          }
                   8168:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8169:            fprintf(ficgp,",");
                   8170:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8171:            fprintf(ficgp,",");
                   8172:          i=i+ncovmodel;
                   8173:        } /* end k */
                   8174:       } /* end k2 */
1.276     brouard  8175:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8176:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8177:     } /* end k1 */
1.223     brouard  8178:   } /* end ng */
                   8179:   /* avoid: */
                   8180:   fflush(ficgp); 
1.126     brouard  8181: }  /* end gnuplot */
                   8182: 
                   8183: 
                   8184: /*************** Moving average **************/
1.219     brouard  8185: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8186:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8187:    
1.222     brouard  8188:    int i, cpt, cptcod;
                   8189:    int modcovmax =1;
                   8190:    int mobilavrange, mob;
                   8191:    int iage=0;
1.288     brouard  8192:    int firstA1=0, firstA2=0;
1.222     brouard  8193: 
1.266     brouard  8194:    double sum=0., sumr=0.;
1.222     brouard  8195:    double age;
1.266     brouard  8196:    double *sumnewp, *sumnewm, *sumnewmr;
                   8197:    double *agemingood, *agemaxgood; 
                   8198:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8199:   
                   8200:   
1.278     brouard  8201:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8202:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8203: 
                   8204:    sumnewp = vector(1,ncovcombmax);
                   8205:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8206:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8207:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8208:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8209:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8210:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8211: 
                   8212:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8213:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8214:      sumnewp[cptcod]=0.;
1.266     brouard  8215:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8216:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8217:    }
                   8218:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8219:   
1.266     brouard  8220:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8221:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8222:      else mobilavrange=mobilav;
                   8223:      for (age=bage; age<=fage; age++)
                   8224:        for (i=1; i<=nlstate;i++)
                   8225:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8226:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8227:      /* We keep the original values on the extreme ages bage, fage and for 
                   8228:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8229:        we use a 5 terms etc. until the borders are no more concerned. 
                   8230:      */ 
                   8231:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8232:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8233:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8234:           sumnewm[cptcod]=0.;
                   8235:           for (i=1; i<=nlstate;i++){
1.222     brouard  8236:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8237:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8238:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8239:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8240:             }
                   8241:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8242:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8243:           } /* end i */
                   8244:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8245:         } /* end cptcod */
1.222     brouard  8246:        }/* end age */
                   8247:      }/* end mob */
1.266     brouard  8248:    }else{
                   8249:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8250:      return -1;
1.266     brouard  8251:    }
                   8252: 
                   8253:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8254:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8255:      if(invalidvarcomb[cptcod]){
                   8256:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8257:        continue;
                   8258:      }
1.219     brouard  8259: 
1.266     brouard  8260:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8261:        sumnewm[cptcod]=0.;
                   8262:        sumnewmr[cptcod]=0.;
                   8263:        for (i=1; i<=nlstate;i++){
                   8264:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8265:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8266:        }
                   8267:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8268:         agemingoodr[cptcod]=age;
                   8269:        }
                   8270:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8271:           agemingood[cptcod]=age;
                   8272:        }
                   8273:      } /* age */
                   8274:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8275:        sumnewm[cptcod]=0.;
1.266     brouard  8276:        sumnewmr[cptcod]=0.;
1.222     brouard  8277:        for (i=1; i<=nlstate;i++){
                   8278:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8279:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8280:        }
                   8281:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8282:         agemaxgoodr[cptcod]=age;
1.222     brouard  8283:        }
                   8284:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8285:         agemaxgood[cptcod]=age;
                   8286:        }
                   8287:      } /* age */
                   8288:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8289:      /* but they will change */
1.288     brouard  8290:      firstA1=0;firstA2=0;
1.266     brouard  8291:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8292:        sumnewm[cptcod]=0.;
                   8293:        sumnewmr[cptcod]=0.;
                   8294:        for (i=1; i<=nlstate;i++){
                   8295:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8296:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8297:        }
                   8298:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8299:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8300:           agemaxgoodr[cptcod]=age;  /* age min */
                   8301:           for (i=1; i<=nlstate;i++)
                   8302:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8303:         }else{ /* bad we change the value with the values of good ages */
                   8304:           for (i=1; i<=nlstate;i++){
                   8305:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8306:           } /* i */
                   8307:         } /* end bad */
                   8308:        }else{
                   8309:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8310:           agemaxgood[cptcod]=age;
                   8311:         }else{ /* bad we change the value with the values of good ages */
                   8312:           for (i=1; i<=nlstate;i++){
                   8313:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8314:           } /* i */
                   8315:         } /* end bad */
                   8316:        }/* end else */
                   8317:        sum=0.;sumr=0.;
                   8318:        for (i=1; i<=nlstate;i++){
                   8319:         sum+=mobaverage[(int)age][i][cptcod];
                   8320:         sumr+=probs[(int)age][i][cptcod];
                   8321:        }
                   8322:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8323:         if(!firstA1){
                   8324:           firstA1=1;
                   8325:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8326:         }
                   8327:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8328:        } /* end bad */
                   8329:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8330:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8331:         if(!firstA2){
                   8332:           firstA2=1;
                   8333:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8334:         }
                   8335:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8336:        } /* end bad */
                   8337:      }/* age */
1.266     brouard  8338: 
                   8339:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8340:        sumnewm[cptcod]=0.;
1.266     brouard  8341:        sumnewmr[cptcod]=0.;
1.222     brouard  8342:        for (i=1; i<=nlstate;i++){
                   8343:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8344:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8345:        } 
                   8346:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8347:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8348:           agemingoodr[cptcod]=age;
                   8349:           for (i=1; i<=nlstate;i++)
                   8350:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8351:         }else{ /* bad we change the value with the values of good ages */
                   8352:           for (i=1; i<=nlstate;i++){
                   8353:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8354:           } /* i */
                   8355:         } /* end bad */
                   8356:        }else{
                   8357:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8358:           agemingood[cptcod]=age;
                   8359:         }else{ /* bad */
                   8360:           for (i=1; i<=nlstate;i++){
                   8361:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8362:           } /* i */
                   8363:         } /* end bad */
                   8364:        }/* end else */
                   8365:        sum=0.;sumr=0.;
                   8366:        for (i=1; i<=nlstate;i++){
                   8367:         sum+=mobaverage[(int)age][i][cptcod];
                   8368:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8369:        }
1.266     brouard  8370:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8371:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8372:        } /* end bad */
                   8373:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8374:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8375:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8376:        } /* end bad */
                   8377:      }/* age */
1.266     brouard  8378: 
1.222     brouard  8379:                
                   8380:      for (age=bage; age<=fage; age++){
1.235     brouard  8381:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8382:        sumnewp[cptcod]=0.;
                   8383:        sumnewm[cptcod]=0.;
                   8384:        for (i=1; i<=nlstate;i++){
                   8385:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8386:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8387:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8388:        }
                   8389:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8390:      }
                   8391:      /* printf("\n"); */
                   8392:      /* } */
1.266     brouard  8393: 
1.222     brouard  8394:      /* brutal averaging */
1.266     brouard  8395:      /* for (i=1; i<=nlstate;i++){ */
                   8396:      /*   for (age=1; age<=bage; age++){ */
                   8397:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8398:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8399:      /*   }     */
                   8400:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8401:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8402:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8403:      /*   } */
                   8404:      /* } /\* end i status *\/ */
                   8405:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8406:      /*   for (age=1; age<=AGESUP; age++){ */
                   8407:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8408:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8409:      /*   } */
                   8410:      /* } */
1.222     brouard  8411:    }/* end cptcod */
1.266     brouard  8412:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8413:    free_vector(agemaxgood,1, ncovcombmax);
                   8414:    free_vector(agemingood,1, ncovcombmax);
                   8415:    free_vector(agemingoodr,1, ncovcombmax);
                   8416:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8417:    free_vector(sumnewm,1, ncovcombmax);
                   8418:    free_vector(sumnewp,1, ncovcombmax);
                   8419:    return 0;
                   8420:  }/* End movingaverage */
1.218     brouard  8421:  
1.126     brouard  8422: 
1.296     brouard  8423:  
1.126     brouard  8424: /************** Forecasting ******************/
1.296     brouard  8425: /* void prevforecast(char fileres[], double dateintmean, double anprojd, double mprojd, double jprojd, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anprojf, double p[], int cptcoveff)*/
                   8426: void prevforecast(char fileres[], double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8427:   /* dateintemean, mean date of interviews
                   8428:      dateprojd, year, month, day of starting projection 
                   8429:      dateprojf date of end of projection;year of end of projection (same day and month as proj1).
1.126     brouard  8430:      agemin, agemax range of age
                   8431:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8432:   */
1.296     brouard  8433:   /* double anprojd, mprojd, jprojd; */
                   8434:   /* double anprojf, mprojf, jprojf; */
1.267     brouard  8435:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8436:   double agec; /* generic age */
1.296     brouard  8437:   double agelim, ppij, yp,yp1,yp2;
1.126     brouard  8438:   double *popeffectif,*popcount;
                   8439:   double ***p3mat;
1.218     brouard  8440:   /* double ***mobaverage; */
1.126     brouard  8441:   char fileresf[FILENAMELENGTH];
                   8442: 
                   8443:   agelim=AGESUP;
1.211     brouard  8444:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8445:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8446:      We still use firstpass and lastpass as another selection.
                   8447:   */
1.214     brouard  8448:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8449:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8450:  
1.201     brouard  8451:   strcpy(fileresf,"F_"); 
                   8452:   strcat(fileresf,fileresu);
1.126     brouard  8453:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8454:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8455:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8456:   }
1.235     brouard  8457:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8458:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8459: 
1.225     brouard  8460:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8461: 
                   8462: 
                   8463:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8464:   if (stepm<=12) stepsize=1;
                   8465:   if(estepm < stepm){
                   8466:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8467:   }
1.270     brouard  8468:   else{
                   8469:     hstepm=estepm;   
                   8470:   }
                   8471:   if(estepm > stepm){ /* Yes every two year */
                   8472:     stepsize=2;
                   8473:   }
1.296     brouard  8474:   hstepm=hstepm/stepm;
1.126     brouard  8475: 
1.296     brouard  8476:   
                   8477:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8478:   /*                              fractional in yp1 *\/ */
                   8479:   /* aintmean=yp; */
                   8480:   /* yp2=modf((yp1*12),&yp); */
                   8481:   /* mintmean=yp; */
                   8482:   /* yp1=modf((yp2*30.5),&yp); */
                   8483:   /* jintmean=yp; */
                   8484:   /* if(jintmean==0) jintmean=1; */
                   8485:   /* if(mintmean==0) mintmean=1; */
1.126     brouard  8486: 
1.296     brouard  8487: 
                   8488:   /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */
                   8489:   /* date2dmy(dateprojd,&jprojd, &mprojd, &anprojd); */
                   8490:   /* date2dmy(dateprojf,&jprojf, &mprojf, &anprojf); */
1.227     brouard  8491:   i1=pow(2,cptcoveff);
1.126     brouard  8492:   if (cptcovn < 1){i1=1;}
                   8493:   
1.296     brouard  8494:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2); 
1.126     brouard  8495:   
                   8496:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8497:   
1.126     brouard  8498: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8499:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8500:   for(k=1; k<=i1;k++){
1.253     brouard  8501:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8502:       continue;
1.227     brouard  8503:     if(invalidvarcomb[k]){
                   8504:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8505:       continue;
                   8506:     }
                   8507:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8508:     for(j=1;j<=cptcoveff;j++) {
                   8509:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8510:     }
1.235     brouard  8511:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8512:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8513:     }
1.227     brouard  8514:     fprintf(ficresf," yearproj age");
                   8515:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8516:       for(i=1; i<=nlstate;i++)               
                   8517:        fprintf(ficresf," p%d%d",i,j);
                   8518:       fprintf(ficresf," wp.%d",j);
                   8519:     }
1.296     brouard  8520:     for (yearp=0; yearp<=(anprojf-anprojd);yearp +=stepsize) {
1.227     brouard  8521:       fprintf(ficresf,"\n");
1.296     brouard  8522:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jprojd,mprojd,anprojd+yearp);   
1.270     brouard  8523:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8524:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8525:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8526:        nhstepm = nhstepm/hstepm; 
                   8527:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8528:        oldm=oldms;savm=savms;
1.268     brouard  8529:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8530:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8531:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8532:        for (h=0; h<=nhstepm; h++){
                   8533:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8534:            break;
                   8535:          }
                   8536:        }
                   8537:        fprintf(ficresf,"\n");
                   8538:        for(j=1;j<=cptcoveff;j++) 
                   8539:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8540:        fprintf(ficresf,"%.f %.f ",anprojd+yearp,agec+h*hstepm/YEARM*stepm);
1.268     brouard  8541:        
                   8542:        for(j=1; j<=nlstate+ndeath;j++) {
                   8543:          ppij=0.;
                   8544:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8545:            if (mobilav>=1)
                   8546:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8547:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8548:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8549:            }
1.268     brouard  8550:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8551:          } /* end i */
                   8552:          fprintf(ficresf," %.3f", ppij);
                   8553:        }/* end j */
1.227     brouard  8554:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8555:       } /* end agec */
1.266     brouard  8556:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8557:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8558:     } /* end yearp */
                   8559:   } /* end  k */
1.219     brouard  8560:        
1.126     brouard  8561:   fclose(ficresf);
1.215     brouard  8562:   printf("End of Computing forecasting \n");
                   8563:   fprintf(ficlog,"End of Computing forecasting\n");
                   8564: 
1.126     brouard  8565: }
                   8566: 
1.269     brouard  8567: /************** Back Forecasting ******************/
1.296     brouard  8568:  /* void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
                   8569:  void prevbackforecast(char fileres[], double ***prevacurrent, double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8570:   /* back1, year, month, day of starting backprojection
1.267     brouard  8571:      agemin, agemax range of age
                   8572:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8573:      anback2 year of end of backprojection (same day and month as back1).
                   8574:      prevacurrent and prev are prevalences.
1.267     brouard  8575:   */
                   8576:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8577:   double agec; /* generic age */
1.302     brouard  8578:   double agelim, ppij, ppi, yp,yp1,yp2; /* ,jintmean,mintmean,aintmean;*/
1.267     brouard  8579:   double *popeffectif,*popcount;
                   8580:   double ***p3mat;
                   8581:   /* double ***mobaverage; */
                   8582:   char fileresfb[FILENAMELENGTH];
                   8583:  
1.268     brouard  8584:   agelim=AGEINF;
1.267     brouard  8585:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8586:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8587:      We still use firstpass and lastpass as another selection.
                   8588:   */
                   8589:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8590:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8591: 
                   8592:   /*Do we need to compute prevalence again?*/
                   8593: 
                   8594:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8595:   
                   8596:   strcpy(fileresfb,"FB_");
                   8597:   strcat(fileresfb,fileresu);
                   8598:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8599:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8600:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8601:   }
                   8602:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8603:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8604:   
                   8605:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8606:   
                   8607:    
                   8608:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8609:   if (stepm<=12) stepsize=1;
                   8610:   if(estepm < stepm){
                   8611:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8612:   }
1.270     brouard  8613:   else{
                   8614:     hstepm=estepm;   
                   8615:   }
                   8616:   if(estepm >= stepm){ /* Yes every two year */
                   8617:     stepsize=2;
                   8618:   }
1.267     brouard  8619:   
                   8620:   hstepm=hstepm/stepm;
1.296     brouard  8621:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8622:   /*                              fractional in yp1 *\/ */
                   8623:   /* aintmean=yp; */
                   8624:   /* yp2=modf((yp1*12),&yp); */
                   8625:   /* mintmean=yp; */
                   8626:   /* yp1=modf((yp2*30.5),&yp); */
                   8627:   /* jintmean=yp; */
                   8628:   /* if(jintmean==0) jintmean=1; */
                   8629:   /* if(mintmean==0) jintmean=1; */
1.267     brouard  8630:   
                   8631:   i1=pow(2,cptcoveff);
                   8632:   if (cptcovn < 1){i1=1;}
                   8633:   
1.296     brouard  8634:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
                   8635:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8636:   
                   8637:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8638:   
                   8639:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8640:   for(k=1; k<=i1;k++){
                   8641:     if(i1 != 1 && TKresult[nres]!= k)
                   8642:       continue;
                   8643:     if(invalidvarcomb[k]){
                   8644:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8645:       continue;
                   8646:     }
1.268     brouard  8647:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8648:     for(j=1;j<=cptcoveff;j++) {
                   8649:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8650:     }
                   8651:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8652:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8653:     }
                   8654:     fprintf(ficresfb," yearbproj age");
                   8655:     for(j=1; j<=nlstate+ndeath;j++){
                   8656:       for(i=1; i<=nlstate;i++)
1.268     brouard  8657:        fprintf(ficresfb," b%d%d",i,j);
                   8658:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8659:     }
1.296     brouard  8660:     for (yearp=0; yearp>=(anbackf-anbackd);yearp -=stepsize) {
1.267     brouard  8661:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8662:       fprintf(ficresfb,"\n");
1.296     brouard  8663:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jbackd,mbackd,anbackd+yearp);
1.273     brouard  8664:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8665:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8666:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8667:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8668:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8669:        nhstepm = nhstepm/hstepm;
                   8670:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8671:        oldm=oldms;savm=savms;
1.268     brouard  8672:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8673:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8674:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8675:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8676:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8677:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8678:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8679:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8680:            break;
                   8681:          }
                   8682:        }
                   8683:        fprintf(ficresfb,"\n");
                   8684:        for(j=1;j<=cptcoveff;j++)
                   8685:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8686:        fprintf(ficresfb,"%.f %.f ",anbackd+yearp,agec-h*hstepm/YEARM*stepm);
1.268     brouard  8687:        for(i=1; i<=nlstate+ndeath;i++) {
                   8688:          ppij=0.;ppi=0.;
                   8689:          for(j=1; j<=nlstate;j++) {
                   8690:            /* if (mobilav==1) */
1.269     brouard  8691:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8692:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8693:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8694:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8695:              /* else { */
                   8696:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8697:              /* } */
1.268     brouard  8698:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8699:          } /* end j */
                   8700:          if(ppi <0.99){
                   8701:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8702:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8703:          }
                   8704:          fprintf(ficresfb," %.3f", ppij);
                   8705:        }/* end j */
1.267     brouard  8706:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8707:       } /* end agec */
                   8708:     } /* end yearp */
                   8709:   } /* end k */
1.217     brouard  8710:   
1.267     brouard  8711:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8712:   
1.267     brouard  8713:   fclose(ficresfb);
                   8714:   printf("End of Computing Back forecasting \n");
                   8715:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8716:        
1.267     brouard  8717: }
1.217     brouard  8718: 
1.269     brouard  8719: /* Variance of prevalence limit: varprlim */
                   8720:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8721:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8722:  
                   8723:    char fileresvpl[FILENAMELENGTH];  
                   8724:    FILE *ficresvpl;
                   8725:    double **oldm, **savm;
                   8726:    double **varpl; /* Variances of prevalence limits by age */   
                   8727:    int i1, k, nres, j ;
                   8728:    
                   8729:     strcpy(fileresvpl,"VPL_");
                   8730:     strcat(fileresvpl,fileresu);
                   8731:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8732:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8733:       exit(0);
                   8734:     }
1.288     brouard  8735:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8736:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8737:     
                   8738:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8739:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8740:     
                   8741:     i1=pow(2,cptcoveff);
                   8742:     if (cptcovn < 1){i1=1;}
                   8743: 
                   8744:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8745:     for(k=1; k<=i1;k++){
                   8746:       if(i1 != 1 && TKresult[nres]!= k)
                   8747:        continue;
                   8748:       fprintf(ficresvpl,"\n#****** ");
                   8749:       printf("\n#****** ");
                   8750:       fprintf(ficlog,"\n#****** ");
                   8751:       for(j=1;j<=cptcoveff;j++) {
                   8752:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8753:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8754:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8755:       }
                   8756:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8757:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8758:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8759:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8760:       }        
                   8761:       fprintf(ficresvpl,"******\n");
                   8762:       printf("******\n");
                   8763:       fprintf(ficlog,"******\n");
                   8764:       
                   8765:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8766:       oldm=oldms;savm=savms;
                   8767:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8768:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8769:       /*}*/
                   8770:     }
                   8771:     
                   8772:     fclose(ficresvpl);
1.288     brouard  8773:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   8774:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  8775: 
                   8776:  }
                   8777: /* Variance of back prevalence: varbprlim */
                   8778:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8779:       /*------- Variance of back (stable) prevalence------*/
                   8780: 
                   8781:    char fileresvbl[FILENAMELENGTH];  
                   8782:    FILE  *ficresvbl;
                   8783: 
                   8784:    double **oldm, **savm;
                   8785:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8786:    int i1, k, nres, j ;
                   8787: 
                   8788:    strcpy(fileresvbl,"VBL_");
                   8789:    strcat(fileresvbl,fileresu);
                   8790:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8791:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8792:      exit(0);
                   8793:    }
                   8794:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8795:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8796:    
                   8797:    
                   8798:    i1=pow(2,cptcoveff);
                   8799:    if (cptcovn < 1){i1=1;}
                   8800:    
                   8801:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8802:      for(k=1; k<=i1;k++){
                   8803:        if(i1 != 1 && TKresult[nres]!= k)
                   8804:         continue;
                   8805:        fprintf(ficresvbl,"\n#****** ");
                   8806:        printf("\n#****** ");
                   8807:        fprintf(ficlog,"\n#****** ");
                   8808:        for(j=1;j<=cptcoveff;j++) {
                   8809:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8810:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8811:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8812:        }
                   8813:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8814:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8815:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8816:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8817:        }
                   8818:        fprintf(ficresvbl,"******\n");
                   8819:        printf("******\n");
                   8820:        fprintf(ficlog,"******\n");
                   8821:        
                   8822:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8823:        oldm=oldms;savm=savms;
                   8824:        
                   8825:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8826:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8827:        /*}*/
                   8828:      }
                   8829:    
                   8830:    fclose(ficresvbl);
                   8831:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8832:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8833: 
                   8834:  } /* End of varbprlim */
                   8835: 
1.126     brouard  8836: /************** Forecasting *****not tested NB*************/
1.227     brouard  8837: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8838:   
1.227     brouard  8839: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8840: /*   int *popage; */
                   8841: /*   double calagedatem, agelim, kk1, kk2; */
                   8842: /*   double *popeffectif,*popcount; */
                   8843: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8844: /*   /\* double ***mobaverage; *\/ */
                   8845: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8846: 
1.227     brouard  8847: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8848: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8849: /*   agelim=AGESUP; */
                   8850: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8851:   
1.227     brouard  8852: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8853:   
                   8854:   
1.227     brouard  8855: /*   strcpy(filerespop,"POP_");  */
                   8856: /*   strcat(filerespop,fileresu); */
                   8857: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8858: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8859: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8860: /*   } */
                   8861: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8862: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8863: 
1.227     brouard  8864: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8865: 
1.227     brouard  8866: /*   /\* if (mobilav!=0) { *\/ */
                   8867: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8868: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8869: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8870: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8871: /*   /\*   } *\/ */
                   8872: /*   /\* } *\/ */
1.126     brouard  8873: 
1.227     brouard  8874: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8875: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8876:   
1.227     brouard  8877: /*   agelim=AGESUP; */
1.126     brouard  8878:   
1.227     brouard  8879: /*   hstepm=1; */
                   8880: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8881:        
1.227     brouard  8882: /*   if (popforecast==1) { */
                   8883: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8884: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8885: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8886: /*     }  */
                   8887: /*     popage=ivector(0,AGESUP); */
                   8888: /*     popeffectif=vector(0,AGESUP); */
                   8889: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8890:     
1.227     brouard  8891: /*     i=1;    */
                   8892: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8893:     
1.227     brouard  8894: /*     imx=i; */
                   8895: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8896: /*   } */
1.218     brouard  8897:   
1.227     brouard  8898: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8899: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8900: /*       k=k+1; */
                   8901: /*       fprintf(ficrespop,"\n#******"); */
                   8902: /*       for(j=1;j<=cptcoveff;j++) { */
                   8903: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8904: /*       } */
                   8905: /*       fprintf(ficrespop,"******\n"); */
                   8906: /*       fprintf(ficrespop,"# Age"); */
                   8907: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8908: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8909:       
1.227     brouard  8910: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8911: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8912:        
1.227     brouard  8913: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8914: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8915: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8916:          
1.227     brouard  8917: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8918: /*       oldm=oldms;savm=savms; */
                   8919: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8920:          
1.227     brouard  8921: /*       for (h=0; h<=nhstepm; h++){ */
                   8922: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8923: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8924: /*         }  */
                   8925: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8926: /*           kk1=0.;kk2=0; */
                   8927: /*           for(i=1; i<=nlstate;i++) {               */
                   8928: /*             if (mobilav==1)  */
                   8929: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8930: /*             else { */
                   8931: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8932: /*             } */
                   8933: /*           } */
                   8934: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8935: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8936: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8937: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8938: /*           } */
                   8939: /*         } */
                   8940: /*         for(i=1; i<=nlstate;i++){ */
                   8941: /*           kk1=0.; */
                   8942: /*           for(j=1; j<=nlstate;j++){ */
                   8943: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8944: /*           } */
                   8945: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8946: /*         } */
1.218     brouard  8947:            
1.227     brouard  8948: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8949: /*           for(j=1; j<=nlstate;j++)  */
                   8950: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8951: /*       } */
                   8952: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8953: /*     } */
                   8954: /*       } */
1.218     brouard  8955:       
1.227     brouard  8956: /*       /\******\/ */
1.218     brouard  8957:       
1.227     brouard  8958: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8959: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8960: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8961: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8962: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8963:          
1.227     brouard  8964: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8965: /*       oldm=oldms;savm=savms; */
                   8966: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8967: /*       for (h=0; h<=nhstepm; h++){ */
                   8968: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8969: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8970: /*         }  */
                   8971: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8972: /*           kk1=0.;kk2=0; */
                   8973: /*           for(i=1; i<=nlstate;i++) {               */
                   8974: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8975: /*           } */
                   8976: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8977: /*         } */
                   8978: /*       } */
                   8979: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8980: /*     } */
                   8981: /*       } */
                   8982: /*     }  */
                   8983: /*   } */
1.218     brouard  8984:   
1.227     brouard  8985: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8986:   
1.227     brouard  8987: /*   if (popforecast==1) { */
                   8988: /*     free_ivector(popage,0,AGESUP); */
                   8989: /*     free_vector(popeffectif,0,AGESUP); */
                   8990: /*     free_vector(popcount,0,AGESUP); */
                   8991: /*   } */
                   8992: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8993: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8994: /*   fclose(ficrespop); */
                   8995: /* } /\* End of popforecast *\/ */
1.218     brouard  8996:  
1.126     brouard  8997: int fileappend(FILE *fichier, char *optionfich)
                   8998: {
                   8999:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   9000:     printf("Problem with file: %s\n", optionfich);
                   9001:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   9002:     return (0);
                   9003:   }
                   9004:   fflush(fichier);
                   9005:   return (1);
                   9006: }
                   9007: 
                   9008: 
                   9009: /**************** function prwizard **********************/
                   9010: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   9011: {
                   9012: 
                   9013:   /* Wizard to print covariance matrix template */
                   9014: 
1.164     brouard  9015:   char ca[32], cb[32];
                   9016:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  9017:   int numlinepar;
                   9018: 
                   9019:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9020:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9021:   for(i=1; i <=nlstate; i++){
                   9022:     jj=0;
                   9023:     for(j=1; j <=nlstate+ndeath; j++){
                   9024:       if(j==i) continue;
                   9025:       jj++;
                   9026:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   9027:       printf("%1d%1d",i,j);
                   9028:       fprintf(ficparo,"%1d%1d",i,j);
                   9029:       for(k=1; k<=ncovmodel;k++){
                   9030:        /*        printf(" %lf",param[i][j][k]); */
                   9031:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   9032:        printf(" 0.");
                   9033:        fprintf(ficparo," 0.");
                   9034:       }
                   9035:       printf("\n");
                   9036:       fprintf(ficparo,"\n");
                   9037:     }
                   9038:   }
                   9039:   printf("# Scales (for hessian or gradient estimation)\n");
                   9040:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   9041:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   9042:   for(i=1; i <=nlstate; i++){
                   9043:     jj=0;
                   9044:     for(j=1; j <=nlstate+ndeath; j++){
                   9045:       if(j==i) continue;
                   9046:       jj++;
                   9047:       fprintf(ficparo,"%1d%1d",i,j);
                   9048:       printf("%1d%1d",i,j);
                   9049:       fflush(stdout);
                   9050:       for(k=1; k<=ncovmodel;k++){
                   9051:        /*      printf(" %le",delti3[i][j][k]); */
                   9052:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   9053:        printf(" 0.");
                   9054:        fprintf(ficparo," 0.");
                   9055:       }
                   9056:       numlinepar++;
                   9057:       printf("\n");
                   9058:       fprintf(ficparo,"\n");
                   9059:     }
                   9060:   }
                   9061:   printf("# Covariance matrix\n");
                   9062: /* # 121 Var(a12)\n\ */
                   9063: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9064: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   9065: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   9066: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   9067: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   9068: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   9069: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   9070:   fflush(stdout);
                   9071:   fprintf(ficparo,"# Covariance matrix\n");
                   9072:   /* # 121 Var(a12)\n\ */
                   9073:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9074:   /* #   ...\n\ */
                   9075:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   9076:   
                   9077:   for(itimes=1;itimes<=2;itimes++){
                   9078:     jj=0;
                   9079:     for(i=1; i <=nlstate; i++){
                   9080:       for(j=1; j <=nlstate+ndeath; j++){
                   9081:        if(j==i) continue;
                   9082:        for(k=1; k<=ncovmodel;k++){
                   9083:          jj++;
                   9084:          ca[0]= k+'a'-1;ca[1]='\0';
                   9085:          if(itimes==1){
                   9086:            printf("#%1d%1d%d",i,j,k);
                   9087:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   9088:          }else{
                   9089:            printf("%1d%1d%d",i,j,k);
                   9090:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   9091:            /*  printf(" %.5le",matcov[i][j]); */
                   9092:          }
                   9093:          ll=0;
                   9094:          for(li=1;li <=nlstate; li++){
                   9095:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   9096:              if(lj==li) continue;
                   9097:              for(lk=1;lk<=ncovmodel;lk++){
                   9098:                ll++;
                   9099:                if(ll<=jj){
                   9100:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   9101:                  if(ll<jj){
                   9102:                    if(itimes==1){
                   9103:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9104:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9105:                    }else{
                   9106:                      printf(" 0.");
                   9107:                      fprintf(ficparo," 0.");
                   9108:                    }
                   9109:                  }else{
                   9110:                    if(itimes==1){
                   9111:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   9112:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   9113:                    }else{
                   9114:                      printf(" 0.");
                   9115:                      fprintf(ficparo," 0.");
                   9116:                    }
                   9117:                  }
                   9118:                }
                   9119:              } /* end lk */
                   9120:            } /* end lj */
                   9121:          } /* end li */
                   9122:          printf("\n");
                   9123:          fprintf(ficparo,"\n");
                   9124:          numlinepar++;
                   9125:        } /* end k*/
                   9126:       } /*end j */
                   9127:     } /* end i */
                   9128:   } /* end itimes */
                   9129: 
                   9130: } /* end of prwizard */
                   9131: /******************* Gompertz Likelihood ******************************/
                   9132: double gompertz(double x[])
                   9133: { 
1.302     brouard  9134:   double A=0.0,B=0.,L=0.0,sump=0.,num=0.;
1.126     brouard  9135:   int i,n=0; /* n is the size of the sample */
                   9136: 
1.220     brouard  9137:   for (i=1;i<=imx ; i++) {
1.126     brouard  9138:     sump=sump+weight[i];
                   9139:     /*    sump=sump+1;*/
                   9140:     num=num+1;
                   9141:   }
1.302     brouard  9142:   L=0.0;
                   9143:   /* agegomp=AGEGOMP; */
1.126     brouard  9144:   /* for (i=0; i<=imx; i++) 
                   9145:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9146: 
1.302     brouard  9147:   for (i=1;i<=imx ; i++) {
                   9148:     /* mu(a)=mu(agecomp)*exp(teta*(age-agegomp))
                   9149:        mu(a)=x[1]*exp(x[2]*(age-agegomp)); x[1] and x[2] are per year.
                   9150:      * L= Product mu(agedeces)exp(-\int_ageexam^agedc mu(u) du ) for a death between agedc (in month) 
                   9151:      *   and agedc +1 month, cens[i]=0: log(x[1]/YEARM)
                   9152:      * +
                   9153:      * exp(-\int_ageexam^agecens mu(u) du ) when censored, cens[i]=1
                   9154:      */
                   9155:      if (wav[i] > 1 || agedc[i] < AGESUP) {
                   9156:        if (cens[i] == 1){
                   9157:         A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   9158:        } else if (cens[i] == 0){
1.126     brouard  9159:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
1.302     brouard  9160:          +log(x[1]/YEARM) +x[2]*(agedc[i]-agegomp)+log(YEARM);
                   9161:       } else
                   9162:         printf("Gompertz cens[%d] neither 1 nor 0\n",i);
1.126     brouard  9163:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
1.302     brouard  9164:        L=L+A*weight[i];
1.126     brouard  9165:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
1.302     brouard  9166:      }
                   9167:   }
1.126     brouard  9168: 
1.302     brouard  9169:   /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
1.126     brouard  9170:  
                   9171:   return -2*L*num/sump;
                   9172: }
                   9173: 
1.136     brouard  9174: #ifdef GSL
                   9175: /******************* Gompertz_f Likelihood ******************************/
                   9176: double gompertz_f(const gsl_vector *v, void *params)
                   9177: { 
1.302     brouard  9178:   double A=0.,B=0.,LL=0.0,sump=0.,num=0.;
1.136     brouard  9179:   double *x= (double *) v->data;
                   9180:   int i,n=0; /* n is the size of the sample */
                   9181: 
                   9182:   for (i=0;i<=imx-1 ; i++) {
                   9183:     sump=sump+weight[i];
                   9184:     /*    sump=sump+1;*/
                   9185:     num=num+1;
                   9186:   }
                   9187:  
                   9188:  
                   9189:   /* for (i=0; i<=imx; i++) 
                   9190:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9191:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9192:   for (i=1;i<=imx ; i++)
                   9193:     {
                   9194:       if (cens[i] == 1 && wav[i]>1)
                   9195:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9196:       
                   9197:       if (cens[i] == 0 && wav[i]>1)
                   9198:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9199:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9200:       
                   9201:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9202:       if (wav[i] > 1 ) { /* ??? */
                   9203:        LL=LL+A*weight[i];
                   9204:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9205:       }
                   9206:     }
                   9207: 
                   9208:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9209:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9210:  
                   9211:   return -2*LL*num/sump;
                   9212: }
                   9213: #endif
                   9214: 
1.126     brouard  9215: /******************* Printing html file ***********/
1.201     brouard  9216: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9217:                  int lastpass, int stepm, int weightopt, char model[],\
                   9218:                  int imx,  double p[],double **matcov,double agemortsup){
                   9219:   int i,k;
                   9220: 
                   9221:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9222:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9223:   for (i=1;i<=2;i++) 
                   9224:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9225:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9226:   fprintf(fichtm,"</ul>");
                   9227: 
                   9228: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9229: 
                   9230:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9231: 
                   9232:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9233:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9234: 
                   9235:  
                   9236:   fflush(fichtm);
                   9237: }
                   9238: 
                   9239: /******************* Gnuplot file **************/
1.201     brouard  9240: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9241: 
                   9242:   char dirfileres[132],optfileres[132];
1.164     brouard  9243: 
1.126     brouard  9244:   int ng;
                   9245: 
                   9246: 
                   9247:   /*#ifdef windows */
                   9248:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9249:     /*#endif */
                   9250: 
                   9251: 
                   9252:   strcpy(dirfileres,optionfilefiname);
                   9253:   strcpy(optfileres,"vpl");
1.199     brouard  9254:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9255:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9256:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9257:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9258:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9259: 
                   9260: } 
                   9261: 
1.136     brouard  9262: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9263: {
1.126     brouard  9264: 
1.136     brouard  9265:   /*-------- data file ----------*/
                   9266:   FILE *fic;
                   9267:   char dummy[]="                         ";
1.240     brouard  9268:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9269:   int lstra;
1.136     brouard  9270:   int linei, month, year,iout;
1.302     brouard  9271:   int noffset=0; /* This is the offset if BOM data file */
1.136     brouard  9272:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9273:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9274:   char *stratrunc;
1.223     brouard  9275: 
1.240     brouard  9276:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9277:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9278: 
1.240     brouard  9279:   for(v=1; v <=ncovcol;v++){
                   9280:     DummyV[v]=0;
                   9281:     FixedV[v]=0;
                   9282:   }
                   9283:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9284:     DummyV[v]=1;
                   9285:     FixedV[v]=0;
                   9286:   }
                   9287:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9288:     DummyV[v]=0;
                   9289:     FixedV[v]=1;
                   9290:   }
                   9291:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9292:     DummyV[v]=1;
                   9293:     FixedV[v]=1;
                   9294:   }
                   9295:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9296:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9297:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9298:   }
1.126     brouard  9299: 
1.136     brouard  9300:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9301:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9302:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9303:   }
1.126     brouard  9304: 
1.302     brouard  9305:     /* Is it a BOM UTF-8 Windows file? */
                   9306:   /* First data line */
                   9307:   linei=0;
                   9308:   while(fgets(line, MAXLINE, fic)) {
                   9309:     noffset=0;
                   9310:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   9311:     {
                   9312:       noffset=noffset+3;
                   9313:       printf("# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);fflush(stdout);
                   9314:       fprintf(ficlog,"# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);
                   9315:       fflush(ficlog); return 1;
                   9316:     }
                   9317:     /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   9318:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
                   9319:     {
                   9320:       noffset=noffset+2;
1.304     brouard  9321:       printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9322:       fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9323:       fflush(ficlog); return 1;
                   9324:     }
                   9325:     else if( line[0] == 0 && line[1] == 0)
                   9326:     {
                   9327:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   9328:        noffset=noffset+4;
1.304     brouard  9329:        printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9330:        fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9331:        fflush(ficlog); return 1;
                   9332:       }
                   9333:     } else{
                   9334:       ;/*printf(" Not a BOM file\n");*/
                   9335:     }
                   9336:         /* If line starts with a # it is a comment */
                   9337:     if (line[noffset] == '#') {
                   9338:       linei=linei+1;
                   9339:       break;
                   9340:     }else{
                   9341:       break;
                   9342:     }
                   9343:   }
                   9344:   fclose(fic);
                   9345:   if((fic=fopen(datafile,"r"))==NULL)    {
                   9346:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9347:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
                   9348:   }
                   9349:   /* Not a Bom file */
                   9350:   
1.136     brouard  9351:   i=1;
                   9352:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9353:     linei=linei+1;
                   9354:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9355:       if(line[j] == '\t')
                   9356:        line[j] = ' ';
                   9357:     }
                   9358:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9359:       ;
                   9360:     };
                   9361:     line[j+1]=0;  /* Trims blanks at end of line */
                   9362:     if(line[0]=='#'){
                   9363:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9364:       printf("Comment line\n%s\n",line);
                   9365:       continue;
                   9366:     }
                   9367:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9368:     strcpy(line, linetmp);
1.223     brouard  9369:     
                   9370:     /* Loops on waves */
                   9371:     for (j=maxwav;j>=1;j--){
                   9372:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9373:        cutv(stra, strb, line, ' '); 
                   9374:        if(strb[0]=='.') { /* Missing value */
                   9375:          lval=-1;
                   9376:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9377:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9378:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9379:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9380:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9381:            return 1;
                   9382:          }
                   9383:        }else{
                   9384:          errno=0;
                   9385:          /* what_kind_of_number(strb); */
                   9386:          dval=strtod(strb,&endptr); 
                   9387:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9388:          /* if(strb != endptr && *endptr == '\0') */
                   9389:          /*    dval=dlval; */
                   9390:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9391:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9392:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9393:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9394:            return 1;
                   9395:          }
                   9396:          cotqvar[j][iv][i]=dval; 
                   9397:          cotvar[j][ntv+iv][i]=dval; 
                   9398:        }
                   9399:        strcpy(line,stra);
1.223     brouard  9400:       }/* end loop ntqv */
1.225     brouard  9401:       
1.223     brouard  9402:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9403:        cutv(stra, strb, line, ' '); 
                   9404:        if(strb[0]=='.') { /* Missing value */
                   9405:          lval=-1;
                   9406:        }else{
                   9407:          errno=0;
                   9408:          lval=strtol(strb,&endptr,10); 
                   9409:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9410:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9411:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9412:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9413:            return 1;
                   9414:          }
                   9415:        }
                   9416:        if(lval <-1 || lval >1){
                   9417:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9418:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9419:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9420:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9421:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9422:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9423:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9424:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9425:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9426:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9427:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9428:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9429:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9430:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9431:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9432:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9433:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9434:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9435:          return 1;
                   9436:        }
                   9437:        cotvar[j][iv][i]=(double)(lval);
                   9438:        strcpy(line,stra);
1.223     brouard  9439:       }/* end loop ntv */
1.225     brouard  9440:       
1.223     brouard  9441:       /* Statuses  at wave */
1.137     brouard  9442:       cutv(stra, strb, line, ' '); 
1.223     brouard  9443:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9444:        lval=-1;
1.136     brouard  9445:       }else{
1.238     brouard  9446:        errno=0;
                   9447:        lval=strtol(strb,&endptr,10); 
                   9448:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9449:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9450:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9451:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9452:          return 1;
                   9453:        }
1.136     brouard  9454:       }
1.225     brouard  9455:       
1.136     brouard  9456:       s[j][i]=lval;
1.225     brouard  9457:       
1.223     brouard  9458:       /* Date of Interview */
1.136     brouard  9459:       strcpy(line,stra);
                   9460:       cutv(stra, strb,line,' ');
1.169     brouard  9461:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9462:       }
1.169     brouard  9463:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9464:        month=99;
                   9465:        year=9999;
1.136     brouard  9466:       }else{
1.225     brouard  9467:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9468:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9469:        return 1;
1.136     brouard  9470:       }
                   9471:       anint[j][i]= (double) year; 
1.302     brouard  9472:       mint[j][i]= (double)month;
                   9473:       /* if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){ */
                   9474:       /*       printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9475:       /*       fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9476:       /* } */
1.136     brouard  9477:       strcpy(line,stra);
1.223     brouard  9478:     } /* End loop on waves */
1.225     brouard  9479:     
1.223     brouard  9480:     /* Date of death */
1.136     brouard  9481:     cutv(stra, strb,line,' '); 
1.169     brouard  9482:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9483:     }
1.169     brouard  9484:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9485:       month=99;
                   9486:       year=9999;
                   9487:     }else{
1.141     brouard  9488:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9489:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9490:       return 1;
1.136     brouard  9491:     }
                   9492:     andc[i]=(double) year; 
                   9493:     moisdc[i]=(double) month; 
                   9494:     strcpy(line,stra);
                   9495:     
1.223     brouard  9496:     /* Date of birth */
1.136     brouard  9497:     cutv(stra, strb,line,' '); 
1.169     brouard  9498:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9499:     }
1.169     brouard  9500:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9501:       month=99;
                   9502:       year=9999;
                   9503:     }else{
1.141     brouard  9504:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9505:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9506:       return 1;
1.136     brouard  9507:     }
                   9508:     if (year==9999) {
1.141     brouard  9509:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9510:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9511:       return 1;
                   9512:       
1.136     brouard  9513:     }
                   9514:     annais[i]=(double)(year);
1.302     brouard  9515:     moisnais[i]=(double)(month);
                   9516:     for (j=1;j<=maxwav;j++){
                   9517:       if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){
                   9518:        printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j,(int)moisnais[i],(int)annais[i]);
                   9519:        fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j, (int)moisnais[i],(int)annais[i]);
                   9520:       }
                   9521:     }
                   9522: 
1.136     brouard  9523:     strcpy(line,stra);
1.225     brouard  9524:     
1.223     brouard  9525:     /* Sample weight */
1.136     brouard  9526:     cutv(stra, strb,line,' '); 
                   9527:     errno=0;
                   9528:     dval=strtod(strb,&endptr); 
                   9529:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9530:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9531:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9532:       fflush(ficlog);
                   9533:       return 1;
                   9534:     }
                   9535:     weight[i]=dval; 
                   9536:     strcpy(line,stra);
1.225     brouard  9537:     
1.223     brouard  9538:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9539:       cutv(stra, strb, line, ' '); 
                   9540:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9541:        lval=-1;
1.311     brouard  9542:        coqvar[iv][i]=NAN; 
                   9543:        covar[ncovcol+iv][i]=NAN; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9544:       }else{
1.225     brouard  9545:        errno=0;
                   9546:        /* what_kind_of_number(strb); */
                   9547:        dval=strtod(strb,&endptr);
                   9548:        /* if(strb != endptr && *endptr == '\0') */
                   9549:        /*   dval=dlval; */
                   9550:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9551:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9552:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9553:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9554:          return 1;
                   9555:        }
                   9556:        coqvar[iv][i]=dval; 
1.226     brouard  9557:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9558:       }
                   9559:       strcpy(line,stra);
                   9560:     }/* end loop nqv */
1.136     brouard  9561:     
1.223     brouard  9562:     /* Covariate values */
1.136     brouard  9563:     for (j=ncovcol;j>=1;j--){
                   9564:       cutv(stra, strb,line,' '); 
1.223     brouard  9565:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9566:        lval=-1;
1.136     brouard  9567:       }else{
1.225     brouard  9568:        errno=0;
                   9569:        lval=strtol(strb,&endptr,10); 
                   9570:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9571:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9572:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9573:          return 1;
                   9574:        }
1.136     brouard  9575:       }
                   9576:       if(lval <-1 || lval >1){
1.225     brouard  9577:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9578:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9579:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9580:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9581:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9582:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9583:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9584:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9585:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9586:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9587:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9588:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9589:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9590:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9591:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9592:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9593:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9594:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9595:        return 1;
1.136     brouard  9596:       }
                   9597:       covar[j][i]=(double)(lval);
                   9598:       strcpy(line,stra);
                   9599:     }  
                   9600:     lstra=strlen(stra);
1.225     brouard  9601:     
1.136     brouard  9602:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9603:       stratrunc = &(stra[lstra-9]);
                   9604:       num[i]=atol(stratrunc);
                   9605:     }
                   9606:     else
                   9607:       num[i]=atol(stra);
                   9608:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9609:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9610:     
                   9611:     i=i+1;
                   9612:   } /* End loop reading  data */
1.225     brouard  9613:   
1.136     brouard  9614:   *imax=i-1; /* Number of individuals */
                   9615:   fclose(fic);
1.225     brouard  9616:   
1.136     brouard  9617:   return (0);
1.164     brouard  9618:   /* endread: */
1.225     brouard  9619:   printf("Exiting readdata: ");
                   9620:   fclose(fic);
                   9621:   return (1);
1.223     brouard  9622: }
1.126     brouard  9623: 
1.234     brouard  9624: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9625:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9626:   while (*p2 == ' ')
1.234     brouard  9627:     p2++; 
                   9628:   /* while ((*p1++ = *p2++) !=0) */
                   9629:   /*   ; */
                   9630:   /* do */
                   9631:   /*   while (*p2 == ' ') */
                   9632:   /*     p2++; */
                   9633:   /* while (*p1++ == *p2++); */
                   9634:   *stri=p2; 
1.145     brouard  9635: }
                   9636: 
1.235     brouard  9637: int decoderesult ( char resultline[], int nres)
1.230     brouard  9638: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9639: {
1.235     brouard  9640:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9641:   char resultsav[MAXLINE];
1.234     brouard  9642:   int resultmodel[MAXLINE];
                   9643:   int modelresult[MAXLINE];
1.230     brouard  9644:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9645: 
1.234     brouard  9646:   removefirstspace(&resultline);
1.230     brouard  9647: 
                   9648:   if (strstr(resultline,"v") !=0){
                   9649:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9650:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9651:     return 1;
                   9652:   }
                   9653:   trimbb(resultsav, resultline);
                   9654:   if (strlen(resultsav) >1){
                   9655:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9656:   }
1.253     brouard  9657:   if(j == 0){ /* Resultline but no = */
                   9658:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9659:     return (0);
                   9660:   }
1.234     brouard  9661:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
1.310     brouard  9662:     printf("ERROR: the number of variables in the resultline, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
                   9663:     fprintf(ficlog,"ERROR: the number of variables in the resultline, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
1.234     brouard  9664:   }
                   9665:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9666:     if(nbocc(resultsav,'=') >1){
                   9667:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
1.310     brouard  9668:                                      resultsav= V4=1 V5=25.1 V3=0 stra= V5=25.1 V3=0 strb= V4=1 */
1.234     brouard  9669:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9670:     }else
                   9671:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9672:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9673:     
1.230     brouard  9674:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9675:     Tvarsel[k]=atoi(strc);
                   9676:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9677:     /* cptcovsel++;     */
                   9678:     if (nbocc(stra,'=') >0)
                   9679:       strcpy(resultsav,stra); /* and analyzes it */
                   9680:   }
1.235     brouard  9681:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9682:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9683:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9684:       match=0;
1.236     brouard  9685:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9686:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9687:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9688:          match=1;
                   9689:          break;
                   9690:        }
                   9691:       }
                   9692:       if(match == 0){
1.310     brouard  9693:        printf("Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9694:        fprintf(ficlog,"Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9695:        return 1;
1.234     brouard  9696:       }
                   9697:     }
                   9698:   }
1.235     brouard  9699:   /* Checking for missing or useless values in comparison of current model needs */
                   9700:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9701:     match=0;
1.235     brouard  9702:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9703:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9704:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9705:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9706:          ++match;
                   9707:        }
                   9708:       }
                   9709:     }
                   9710:     if(match == 0){
                   9711:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
1.310     brouard  9712:       fprintf(ficlog,"Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9713:       return 1;
1.234     brouard  9714:     }else if(match > 1){
                   9715:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
1.310     brouard  9716:       fprintf(ficlog,"Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9717:       return 1;
1.234     brouard  9718:     }
                   9719:   }
1.235     brouard  9720:       
1.234     brouard  9721:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9722:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9723:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9724:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9725:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9726:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9727:   /*    1 0 0 0 */
                   9728:   /*    2 1 0 0 */
                   9729:   /*    3 0 1 0 */ 
                   9730:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9731:   /*    5 0 0 1 */
                   9732:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9733:   /*    7 0 1 1 */
                   9734:   /*    8 1 1 1 */
1.237     brouard  9735:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9736:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9737:   /* V5*age V5 known which value for nres?  */
                   9738:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9739:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9740:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9741:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9742:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9743:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9744:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9745:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9746:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9747:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9748:       k4++;;
                   9749:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9750:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9751:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9752:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9753:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9754:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9755:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9756:       k4q++;;
                   9757:     }
                   9758:   }
1.234     brouard  9759:   
1.235     brouard  9760:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9761:   return (0);
                   9762: }
1.235     brouard  9763: 
1.230     brouard  9764: int decodemodel( char model[], int lastobs)
                   9765:  /**< This routine decodes the model and returns:
1.224     brouard  9766:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9767:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9768:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9769:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9770:        * - cptcovage number of covariates with age*products =2
                   9771:        * - cptcovs number of simple covariates
                   9772:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9773:        *     which is a new column after the 9 (ncovcol) variables. 
                   9774:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9775:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9776:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9777:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9778:        */
1.136     brouard  9779: {
1.238     brouard  9780:   int i, j, k, ks, v;
1.227     brouard  9781:   int  j1, k1, k2, k3, k4;
1.136     brouard  9782:   char modelsav[80];
1.145     brouard  9783:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9784:   char *strpt;
1.136     brouard  9785: 
1.145     brouard  9786:   /*removespace(model);*/
1.136     brouard  9787:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9788:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9789:     if (strstr(model,"AGE") !=0){
1.192     brouard  9790:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9791:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9792:       return 1;
                   9793:     }
1.141     brouard  9794:     if (strstr(model,"v") !=0){
                   9795:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9796:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9797:       return 1;
                   9798:     }
1.187     brouard  9799:     strcpy(modelsav,model); 
                   9800:     if ((strpt=strstr(model,"age*age")) !=0){
                   9801:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9802:       if(strpt != model){
1.234     brouard  9803:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9804:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9805:  corresponding column of parameters.\n",model);
1.234     brouard  9806:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9807:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9808:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9809:        return 1;
1.225     brouard  9810:       }
1.187     brouard  9811:       nagesqr=1;
                   9812:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9813:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9814:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9815:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9816:       else 
1.234     brouard  9817:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9818:     }else
                   9819:       nagesqr=0;
                   9820:     if (strlen(modelsav) >1){
                   9821:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9822:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9823:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9824:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9825:                     * cst, age and age*age 
                   9826:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9827:       /* including age products which are counted in cptcovage.
                   9828:        * but the covariates which are products must be treated 
                   9829:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9830:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9831:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9832:       
                   9833:       
1.187     brouard  9834:       /*   Design
                   9835:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9836:        *  <          ncovcol=8                >
                   9837:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9838:        *   k=  1    2      3       4     5       6      7        8
                   9839:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9840:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9841:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9842:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9843:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9844:        *  Tage[++cptcovage]=k
                   9845:        *       if products, new covar are created after ncovcol with k1
                   9846:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9847:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9848:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9849:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9850:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9851:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9852:        *  <          ncovcol=8                >
                   9853:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9854:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9855:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9856:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9857:        * p Tprod[1]@2={                         6, 5}
                   9858:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9859:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9860:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9861:        *How to reorganize?
                   9862:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9863:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9864:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9865:        * Struct []
                   9866:        */
1.225     brouard  9867:       
1.187     brouard  9868:       /* This loop fills the array Tvar from the string 'model'.*/
                   9869:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9870:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9871:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9872:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9873:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9874:       /*       k=1 Tvar[1]=2 (from V2) */
                   9875:       /*       k=5 Tvar[5] */
                   9876:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9877:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9878:       /*       } */
1.198     brouard  9879:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9880:       /*
                   9881:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9882:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9883:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9884:       }
1.187     brouard  9885:       cptcovage=0;
                   9886:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9887:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9888:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9889:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9890:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9891:        /*scanf("%d",i);*/
                   9892:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9893:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9894:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9895:            /* covar is not filled and then is empty */
                   9896:            cptcovprod--;
                   9897:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9898:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9899:            Typevar[k]=1;  /* 1 for age product */
                   9900:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9901:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9902:            /*printf("stre=%s ", stre);*/
                   9903:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9904:            cptcovprod--;
                   9905:            cutl(stre,strb,strc,'V');
                   9906:            Tvar[k]=atoi(stre);
                   9907:            Typevar[k]=1;  /* 1 for age product */
                   9908:            cptcovage++;
                   9909:            Tage[cptcovage]=k;
                   9910:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9911:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9912:            cptcovn++;
                   9913:            cptcovprodnoage++;k1++;
                   9914:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9915:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9916:                                                because this model-covariate is a construction we invent a new column
                   9917:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9918:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9919:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9920:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9921:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9922:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9923:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9924:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9925:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9926:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9927:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9928:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9929:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9930:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9931:            for (i=1; i<=lastobs;i++){
                   9932:              /* Computes the new covariate which is a product of
                   9933:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9934:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9935:            }
                   9936:          } /* End age is not in the model */
                   9937:        } /* End if model includes a product */
                   9938:        else { /* no more sum */
                   9939:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9940:          /*  scanf("%d",i);*/
                   9941:          cutl(strd,strc,strb,'V');
                   9942:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9943:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9944:          Tvar[k]=atoi(strd);
                   9945:          Typevar[k]=0;  /* 0 for simple covariates */
                   9946:        }
                   9947:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9948:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9949:                                  scanf("%d",i);*/
1.187     brouard  9950:       } /* end of loop + on total covariates */
                   9951:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9952:   } /* end if strlen(model == 0) */
1.136     brouard  9953:   
                   9954:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9955:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9956:   
1.136     brouard  9957:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9958:      printf("cptcovprod=%d ", cptcovprod);
                   9959:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9960:      scanf("%d ",i);*/
                   9961: 
                   9962: 
1.230     brouard  9963: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9964:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9965: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9966:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9967:    k =           1    2   3     4       5       6      7      8        9
                   9968:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9969:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9970:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9971:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9972:          Tmodelind[combination of covar]=k;
1.225     brouard  9973: */  
                   9974: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9975:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9976:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9977:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9978:   printf("Model=%s\n\
                   9979: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9980: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9981: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9982:   fprintf(ficlog,"Model=%s\n\
                   9983: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9984: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9985: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  9986:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9987:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9988:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9989:       Fixed[k]= 0;
                   9990:       Dummy[k]= 0;
1.225     brouard  9991:       ncoveff++;
1.232     brouard  9992:       ncovf++;
1.234     brouard  9993:       nsd++;
                   9994:       modell[k].maintype= FTYPE;
                   9995:       TvarsD[nsd]=Tvar[k];
                   9996:       TvarsDind[nsd]=k;
                   9997:       TvarF[ncovf]=Tvar[k];
                   9998:       TvarFind[ncovf]=k;
                   9999:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10000:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10001:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   10002:       Fixed[k]= 0;
                   10003:       Dummy[k]= 0;
                   10004:       ncoveff++;
                   10005:       ncovf++;
                   10006:       modell[k].maintype= FTYPE;
                   10007:       TvarF[ncovf]=Tvar[k];
                   10008:       TvarFind[ncovf]=k;
1.230     brouard  10009:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  10010:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  10011:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  10012:       Fixed[k]= 0;
                   10013:       Dummy[k]= 1;
1.230     brouard  10014:       nqfveff++;
1.234     brouard  10015:       modell[k].maintype= FTYPE;
                   10016:       modell[k].subtype= FQ;
                   10017:       nsq++;
                   10018:       TvarsQ[nsq]=Tvar[k];
                   10019:       TvarsQind[nsq]=k;
1.232     brouard  10020:       ncovf++;
1.234     brouard  10021:       TvarF[ncovf]=Tvar[k];
                   10022:       TvarFind[ncovf]=k;
1.231     brouard  10023:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  10024:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  10025:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  10026:       Fixed[k]= 1;
                   10027:       Dummy[k]= 0;
1.225     brouard  10028:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  10029:       modell[k].maintype= VTYPE;
                   10030:       modell[k].subtype= VD;
                   10031:       nsd++;
                   10032:       TvarsD[nsd]=Tvar[k];
                   10033:       TvarsDind[nsd]=k;
                   10034:       ncovv++; /* Only simple time varying variables */
                   10035:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10036:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10037:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   10038:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  10039:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   10040:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  10041:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  10042:       Fixed[k]= 1;
                   10043:       Dummy[k]= 1;
                   10044:       nqtveff++;
                   10045:       modell[k].maintype= VTYPE;
                   10046:       modell[k].subtype= VQ;
                   10047:       ncovv++; /* Only simple time varying variables */
                   10048:       nsq++;
                   10049:       TvarsQ[nsq]=Tvar[k];
                   10050:       TvarsQind[nsq]=k;
                   10051:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10052:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10053:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   10054:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  10055:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   10056:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   10057:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  10058:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  10059:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  10060:       ncova++;
                   10061:       TvarA[ncova]=Tvar[k];
                   10062:       TvarAind[ncova]=k;
1.231     brouard  10063:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  10064:        Fixed[k]= 2;
                   10065:        Dummy[k]= 2;
                   10066:        modell[k].maintype= ATYPE;
                   10067:        modell[k].subtype= APFD;
                   10068:        /* ncoveff++; */
1.227     brouard  10069:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  10070:        Fixed[k]= 2;
                   10071:        Dummy[k]= 3;
                   10072:        modell[k].maintype= ATYPE;
                   10073:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   10074:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  10075:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  10076:        Fixed[k]= 3;
                   10077:        Dummy[k]= 2;
                   10078:        modell[k].maintype= ATYPE;
                   10079:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   10080:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  10081:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10082:        Fixed[k]= 3;
                   10083:        Dummy[k]= 3;
                   10084:        modell[k].maintype= ATYPE;
                   10085:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   10086:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  10087:       }
                   10088:     }else if (Typevar[k] == 2) {  /* product without age */
                   10089:       k1=Tposprod[k];
                   10090:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  10091:        if(Tvard[k1][2] <=ncovcol){
                   10092:          Fixed[k]= 1;
                   10093:          Dummy[k]= 0;
                   10094:          modell[k].maintype= FTYPE;
                   10095:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   10096:          ncovf++; /* Fixed variables without age */
                   10097:          TvarF[ncovf]=Tvar[k];
                   10098:          TvarFind[ncovf]=k;
                   10099:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10100:          Fixed[k]= 0;  /* or 2 ?*/
                   10101:          Dummy[k]= 1;
                   10102:          modell[k].maintype= FTYPE;
                   10103:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   10104:          ncovf++; /* Varying variables without age */
                   10105:          TvarF[ncovf]=Tvar[k];
                   10106:          TvarFind[ncovf]=k;
                   10107:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10108:          Fixed[k]= 1;
                   10109:          Dummy[k]= 0;
                   10110:          modell[k].maintype= VTYPE;
                   10111:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   10112:          ncovv++; /* Varying variables without age */
                   10113:          TvarV[ncovv]=Tvar[k];
                   10114:          TvarVind[ncovv]=k;
                   10115:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10116:          Fixed[k]= 1;
                   10117:          Dummy[k]= 1;
                   10118:          modell[k].maintype= VTYPE;
                   10119:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   10120:          ncovv++; /* Varying variables without age */
                   10121:          TvarV[ncovv]=Tvar[k];
                   10122:          TvarVind[ncovv]=k;
                   10123:        }
1.227     brouard  10124:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  10125:        if(Tvard[k1][2] <=ncovcol){
                   10126:          Fixed[k]= 0;  /* or 2 ?*/
                   10127:          Dummy[k]= 1;
                   10128:          modell[k].maintype= FTYPE;
                   10129:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   10130:          ncovf++; /* Fixed variables without age */
                   10131:          TvarF[ncovf]=Tvar[k];
                   10132:          TvarFind[ncovf]=k;
                   10133:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10134:          Fixed[k]= 1;
                   10135:          Dummy[k]= 1;
                   10136:          modell[k].maintype= VTYPE;
                   10137:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   10138:          ncovv++; /* Varying variables without age */
                   10139:          TvarV[ncovv]=Tvar[k];
                   10140:          TvarVind[ncovv]=k;
                   10141:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10142:          Fixed[k]= 1;
                   10143:          Dummy[k]= 1;
                   10144:          modell[k].maintype= VTYPE;
                   10145:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   10146:          ncovv++; /* Varying variables without age */
                   10147:          TvarV[ncovv]=Tvar[k];
                   10148:          TvarVind[ncovv]=k;
                   10149:          ncovv++; /* Varying variables without age */
                   10150:          TvarV[ncovv]=Tvar[k];
                   10151:          TvarVind[ncovv]=k;
                   10152:        }
1.227     brouard  10153:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  10154:        if(Tvard[k1][2] <=ncovcol){
                   10155:          Fixed[k]= 1;
                   10156:          Dummy[k]= 1;
                   10157:          modell[k].maintype= VTYPE;
                   10158:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   10159:          ncovv++; /* Varying variables without age */
                   10160:          TvarV[ncovv]=Tvar[k];
                   10161:          TvarVind[ncovv]=k;
                   10162:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10163:          Fixed[k]= 1;
                   10164:          Dummy[k]= 1;
                   10165:          modell[k].maintype= VTYPE;
                   10166:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   10167:          ncovv++; /* Varying variables without age */
                   10168:          TvarV[ncovv]=Tvar[k];
                   10169:          TvarVind[ncovv]=k;
                   10170:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10171:          Fixed[k]= 1;
                   10172:          Dummy[k]= 0;
                   10173:          modell[k].maintype= VTYPE;
                   10174:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   10175:          ncovv++; /* Varying variables without age */
                   10176:          TvarV[ncovv]=Tvar[k];
                   10177:          TvarVind[ncovv]=k;
                   10178:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10179:          Fixed[k]= 1;
                   10180:          Dummy[k]= 1;
                   10181:          modell[k].maintype= VTYPE;
                   10182:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   10183:          ncovv++; /* Varying variables without age */
                   10184:          TvarV[ncovv]=Tvar[k];
                   10185:          TvarVind[ncovv]=k;
                   10186:        }
1.227     brouard  10187:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10188:        if(Tvard[k1][2] <=ncovcol){
                   10189:          Fixed[k]= 1;
                   10190:          Dummy[k]= 1;
                   10191:          modell[k].maintype= VTYPE;
                   10192:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   10193:          ncovv++; /* Varying variables without age */
                   10194:          TvarV[ncovv]=Tvar[k];
                   10195:          TvarVind[ncovv]=k;
                   10196:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10197:          Fixed[k]= 1;
                   10198:          Dummy[k]= 1;
                   10199:          modell[k].maintype= VTYPE;
                   10200:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   10201:          ncovv++; /* Varying variables without age */
                   10202:          TvarV[ncovv]=Tvar[k];
                   10203:          TvarVind[ncovv]=k;
                   10204:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10205:          Fixed[k]= 1;
                   10206:          Dummy[k]= 1;
                   10207:          modell[k].maintype= VTYPE;
                   10208:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   10209:          ncovv++; /* Varying variables without age */
                   10210:          TvarV[ncovv]=Tvar[k];
                   10211:          TvarVind[ncovv]=k;
                   10212:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10213:          Fixed[k]= 1;
                   10214:          Dummy[k]= 1;
                   10215:          modell[k].maintype= VTYPE;
                   10216:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10217:          ncovv++; /* Varying variables without age */
                   10218:          TvarV[ncovv]=Tvar[k];
                   10219:          TvarVind[ncovv]=k;
                   10220:        }
1.227     brouard  10221:       }else{
1.240     brouard  10222:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10223:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10224:       } /*end k1*/
1.225     brouard  10225:     }else{
1.226     brouard  10226:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10227:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10228:     }
1.227     brouard  10229:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10230:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10231:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10232:   }
                   10233:   /* Searching for doublons in the model */
                   10234:   for(k1=1; k1<= cptcovt;k1++){
                   10235:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10236:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10237:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10238:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10239:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10240:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10241:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10242:            return(1);
                   10243:          }
                   10244:        }else if (Typevar[k1] ==2){
                   10245:          k3=Tposprod[k1];
                   10246:          k4=Tposprod[k2];
                   10247:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10248:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10249:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10250:            return(1);
                   10251:          }
                   10252:        }
1.227     brouard  10253:       }
                   10254:     }
1.225     brouard  10255:   }
                   10256:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10257:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10258:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10259:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10260:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10261:   /*endread:*/
1.225     brouard  10262:   printf("Exiting decodemodel: ");
                   10263:   return (1);
1.136     brouard  10264: }
                   10265: 
1.169     brouard  10266: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10267: {/* Check ages at death */
1.136     brouard  10268:   int i, m;
1.218     brouard  10269:   int firstone=0;
                   10270:   
1.136     brouard  10271:   for (i=1; i<=imx; i++) {
                   10272:     for(m=2; (m<= maxwav); m++) {
                   10273:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10274:        anint[m][i]=9999;
1.216     brouard  10275:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10276:          s[m][i]=-1;
1.136     brouard  10277:       }
                   10278:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10279:        *nberr = *nberr + 1;
1.218     brouard  10280:        if(firstone == 0){
                   10281:          firstone=1;
1.260     brouard  10282:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10283:        }
1.262     brouard  10284:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10285:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10286:       }
                   10287:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10288:        (*nberr)++;
1.259     brouard  10289:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10290:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10291:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10292:       }
                   10293:     }
                   10294:   }
                   10295: 
                   10296:   for (i=1; i<=imx; i++)  {
                   10297:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10298:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10299:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10300:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10301:          if(agedc[i]>0){
                   10302:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10303:              agev[m][i]=agedc[i];
1.214     brouard  10304:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10305:            }else {
1.136     brouard  10306:              if ((int)andc[i]!=9999){
                   10307:                nbwarn++;
                   10308:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10309:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10310:                agev[m][i]=-1;
                   10311:              }
                   10312:            }
1.169     brouard  10313:          } /* agedc > 0 */
1.214     brouard  10314:        } /* end if */
1.136     brouard  10315:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10316:                                 years but with the precision of a month */
                   10317:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10318:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10319:            agev[m][i]=1;
                   10320:          else if(agev[m][i] < *agemin){ 
                   10321:            *agemin=agev[m][i];
                   10322:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10323:          }
                   10324:          else if(agev[m][i] >*agemax){
                   10325:            *agemax=agev[m][i];
1.156     brouard  10326:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10327:          }
                   10328:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10329:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10330:        } /* en if 9*/
1.136     brouard  10331:        else { /* =9 */
1.214     brouard  10332:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10333:          agev[m][i]=1;
                   10334:          s[m][i]=-1;
                   10335:        }
                   10336:       }
1.214     brouard  10337:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10338:        agev[m][i]=1;
1.214     brouard  10339:       else{
                   10340:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10341:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10342:        agev[m][i]=0;
                   10343:       }
                   10344:     } /* End for lastpass */
                   10345:   }
1.136     brouard  10346:     
                   10347:   for (i=1; i<=imx; i++)  {
                   10348:     for(m=firstpass; (m<=lastpass); m++){
                   10349:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10350:        (*nberr)++;
1.136     brouard  10351:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10352:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10353:        return 1;
                   10354:       }
                   10355:     }
                   10356:   }
                   10357: 
                   10358:   /*for (i=1; i<=imx; i++){
                   10359:   for (m=firstpass; (m<lastpass); m++){
                   10360:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10361: }
                   10362: 
                   10363: }*/
                   10364: 
                   10365: 
1.139     brouard  10366:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10367:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10368: 
                   10369:   return (0);
1.164     brouard  10370:  /* endread:*/
1.136     brouard  10371:     printf("Exiting calandcheckages: ");
                   10372:     return (1);
                   10373: }
                   10374: 
1.172     brouard  10375: #if defined(_MSC_VER)
                   10376: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10377: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10378: //#include "stdafx.h"
                   10379: //#include <stdio.h>
                   10380: //#include <tchar.h>
                   10381: //#include <windows.h>
                   10382: //#include <iostream>
                   10383: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10384: 
                   10385: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10386: 
                   10387: BOOL IsWow64()
                   10388: {
                   10389:        BOOL bIsWow64 = FALSE;
                   10390: 
                   10391:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10392:        //  (HANDLE, PBOOL);
                   10393: 
                   10394:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10395: 
                   10396:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10397:        const char funcName[] = "IsWow64Process";
                   10398:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10399:                GetProcAddress(module, funcName);
                   10400: 
                   10401:        if (NULL != fnIsWow64Process)
                   10402:        {
                   10403:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10404:                        &bIsWow64))
                   10405:                        //throw std::exception("Unknown error");
                   10406:                        printf("Unknown error\n");
                   10407:        }
                   10408:        return bIsWow64 != FALSE;
                   10409: }
                   10410: #endif
1.177     brouard  10411: 
1.191     brouard  10412: void syscompilerinfo(int logged)
1.292     brouard  10413: {
                   10414: #include <stdint.h>
                   10415: 
                   10416:   /* #include "syscompilerinfo.h"*/
1.185     brouard  10417:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10418:    /* /GS /W3 /Gy
                   10419:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10420:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10421:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10422:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10423:    */ 
                   10424:    /* 64 bits */
1.185     brouard  10425:    /*
                   10426:      /GS /W3 /Gy
                   10427:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10428:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10429:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10430:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10431:    /* Optimization are useless and O3 is slower than O2 */
                   10432:    /*
                   10433:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10434:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10435:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10436:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10437:    */
1.186     brouard  10438:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10439:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10440:       /PDB:"visual studio
                   10441:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10442:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10443:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10444:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10445:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10446:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10447:       uiAccess='false'"
                   10448:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10449:       /NOLOGO /TLBID:1
                   10450:    */
1.292     brouard  10451: 
                   10452: 
1.177     brouard  10453: #if defined __INTEL_COMPILER
1.178     brouard  10454: #if defined(__GNUC__)
                   10455:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10456: #endif
1.177     brouard  10457: #elif defined(__GNUC__) 
1.179     brouard  10458: #ifndef  __APPLE__
1.174     brouard  10459: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10460: #endif
1.177     brouard  10461:    struct utsname sysInfo;
1.178     brouard  10462:    int cross = CROSS;
                   10463:    if (cross){
                   10464:           printf("Cross-");
1.191     brouard  10465:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10466:    }
1.174     brouard  10467: #endif
                   10468: 
1.191     brouard  10469:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10470: #if defined(__clang__)
1.191     brouard  10471:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10472: #endif
                   10473: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10474:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10475: #endif
                   10476: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10477:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10478: #endif
                   10479: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10480:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10481: #endif
                   10482: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10483:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10484: #endif
                   10485: #if defined(_MSC_VER)
1.191     brouard  10486:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10487: #endif
                   10488: #if defined(__PGI)
1.191     brouard  10489:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10490: #endif
                   10491: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10492:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10493: #endif
1.191     brouard  10494:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10495:    
1.167     brouard  10496: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10497: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10498:     // Windows (x64 and x86)
1.191     brouard  10499:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10500: #elif __unix__ // all unices, not all compilers
                   10501:     // Unix
1.191     brouard  10502:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10503: #elif __linux__
                   10504:     // linux
1.191     brouard  10505:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10506: #elif __APPLE__
1.174     brouard  10507:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10508:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10509: #endif
                   10510: 
                   10511: /*  __MINGW32__          */
                   10512: /*  __CYGWIN__  */
                   10513: /* __MINGW64__  */
                   10514: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10515: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10516: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10517: /* _WIN64  // Defined for applications for Win64. */
                   10518: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10519: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10520: 
1.167     brouard  10521: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10522:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10523: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10524:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10525: #else
1.191     brouard  10526:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10527: #endif
                   10528: 
1.169     brouard  10529: #if defined(__GNUC__)
                   10530: # if defined(__GNUC_PATCHLEVEL__)
                   10531: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10532:                             + __GNUC_MINOR__ * 100 \
                   10533:                             + __GNUC_PATCHLEVEL__)
                   10534: # else
                   10535: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10536:                             + __GNUC_MINOR__ * 100)
                   10537: # endif
1.174     brouard  10538:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10539:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10540: 
                   10541:    if (uname(&sysInfo) != -1) {
                   10542:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10543:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10544:    }
                   10545:    else
                   10546:       perror("uname() error");
1.179     brouard  10547:    //#ifndef __INTEL_COMPILER 
                   10548: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10549:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10550:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10551: #endif
1.169     brouard  10552: #endif
1.172     brouard  10553: 
1.286     brouard  10554:    //   void main ()
1.172     brouard  10555:    //   {
1.169     brouard  10556: #if defined(_MSC_VER)
1.174     brouard  10557:    if (IsWow64()){
1.191     brouard  10558:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10559:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10560:    }
                   10561:    else{
1.191     brouard  10562:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10563:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10564:    }
1.172     brouard  10565:    //     printf("\nPress Enter to continue...");
                   10566:    //     getchar();
                   10567:    //   }
                   10568: 
1.169     brouard  10569: #endif
                   10570:    
1.167     brouard  10571: 
1.219     brouard  10572: }
1.136     brouard  10573: 
1.219     brouard  10574: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10575:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10576:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10577:   /* double ftolpl = 1.e-10; */
1.180     brouard  10578:   double age, agebase, agelim;
1.203     brouard  10579:   double tot;
1.180     brouard  10580: 
1.202     brouard  10581:   strcpy(filerespl,"PL_");
                   10582:   strcat(filerespl,fileresu);
                   10583:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10584:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10585:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10586:   }
1.288     brouard  10587:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10588:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10589:   pstamp(ficrespl);
1.288     brouard  10590:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10591:   fprintf(ficrespl,"#Age ");
                   10592:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10593:   fprintf(ficrespl,"\n");
1.180     brouard  10594:   
1.219     brouard  10595:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10596: 
1.219     brouard  10597:   agebase=ageminpar;
                   10598:   agelim=agemaxpar;
1.180     brouard  10599: 
1.227     brouard  10600:   /* i1=pow(2,ncoveff); */
1.234     brouard  10601:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10602:   if (cptcovn < 1){i1=1;}
1.180     brouard  10603: 
1.238     brouard  10604:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10605:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10606:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10607:        continue;
1.235     brouard  10608: 
1.238     brouard  10609:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10610:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10611:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10612:       /* k=k+1; */
                   10613:       /* to clean */
                   10614:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10615:       fprintf(ficrespl,"#******");
                   10616:       printf("#******");
                   10617:       fprintf(ficlog,"#******");
                   10618:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10619:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10620:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10621:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10622:       }
                   10623:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10624:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10625:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10626:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10627:       }
                   10628:       fprintf(ficrespl,"******\n");
                   10629:       printf("******\n");
                   10630:       fprintf(ficlog,"******\n");
                   10631:       if(invalidvarcomb[k]){
                   10632:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10633:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10634:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10635:        continue;
                   10636:       }
1.219     brouard  10637: 
1.238     brouard  10638:       fprintf(ficrespl,"#Age ");
                   10639:       for(j=1;j<=cptcoveff;j++) {
                   10640:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10641:       }
                   10642:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10643:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10644:     
1.238     brouard  10645:       for (age=agebase; age<=agelim; age++){
                   10646:        /* for (age=agebase; age<=agebase; age++){ */
                   10647:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10648:        fprintf(ficrespl,"%.0f ",age );
                   10649:        for(j=1;j<=cptcoveff;j++)
                   10650:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10651:        tot=0.;
                   10652:        for(i=1; i<=nlstate;i++){
                   10653:          tot +=  prlim[i][i];
                   10654:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10655:        }
                   10656:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10657:       } /* Age */
                   10658:       /* was end of cptcod */
                   10659:     } /* cptcov */
                   10660:   } /* nres */
1.219     brouard  10661:   return 0;
1.180     brouard  10662: }
                   10663: 
1.218     brouard  10664: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10665:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10666:        
                   10667:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10668:    * at any age between ageminpar and agemaxpar
                   10669:         */
1.235     brouard  10670:   int i, j, k, i1, nres=0 ;
1.217     brouard  10671:   /* double ftolpl = 1.e-10; */
                   10672:   double age, agebase, agelim;
                   10673:   double tot;
1.218     brouard  10674:   /* double ***mobaverage; */
                   10675:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10676: 
                   10677:   strcpy(fileresplb,"PLB_");
                   10678:   strcat(fileresplb,fileresu);
                   10679:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10680:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10681:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10682:   }
1.288     brouard  10683:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10684:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10685:   pstamp(ficresplb);
1.288     brouard  10686:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10687:   fprintf(ficresplb,"#Age ");
                   10688:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10689:   fprintf(ficresplb,"\n");
                   10690:   
1.218     brouard  10691:   
                   10692:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10693:   
                   10694:   agebase=ageminpar;
                   10695:   agelim=agemaxpar;
                   10696:   
                   10697:   
1.227     brouard  10698:   i1=pow(2,cptcoveff);
1.218     brouard  10699:   if (cptcovn < 1){i1=1;}
1.227     brouard  10700:   
1.238     brouard  10701:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10702:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10703:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10704:        continue;
                   10705:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10706:       fprintf(ficresplb,"#******");
                   10707:       printf("#******");
                   10708:       fprintf(ficlog,"#******");
                   10709:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10710:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10711:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10712:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10713:       }
                   10714:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10715:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10716:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10717:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10718:       }
                   10719:       fprintf(ficresplb,"******\n");
                   10720:       printf("******\n");
                   10721:       fprintf(ficlog,"******\n");
                   10722:       if(invalidvarcomb[k]){
                   10723:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10724:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10725:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10726:        continue;
                   10727:       }
1.218     brouard  10728:     
1.238     brouard  10729:       fprintf(ficresplb,"#Age ");
                   10730:       for(j=1;j<=cptcoveff;j++) {
                   10731:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10732:       }
                   10733:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10734:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10735:     
                   10736:     
1.238     brouard  10737:       for (age=agebase; age<=agelim; age++){
                   10738:        /* for (age=agebase; age<=agebase; age++){ */
                   10739:        if(mobilavproj > 0){
                   10740:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10741:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10742:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10743:        }else if (mobilavproj == 0){
                   10744:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10745:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10746:          exit(1);
                   10747:        }else{
                   10748:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10749:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10750:          /* printf("TOTOT\n"); */
                   10751:           /* exit(1); */
1.238     brouard  10752:        }
                   10753:        fprintf(ficresplb,"%.0f ",age );
                   10754:        for(j=1;j<=cptcoveff;j++)
                   10755:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10756:        tot=0.;
                   10757:        for(i=1; i<=nlstate;i++){
                   10758:          tot +=  bprlim[i][i];
                   10759:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10760:        }
                   10761:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10762:       } /* Age */
                   10763:       /* was end of cptcod */
1.255     brouard  10764:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10765:     } /* end of any combination */
                   10766:   } /* end of nres */  
1.218     brouard  10767:   /* hBijx(p, bage, fage); */
                   10768:   /* fclose(ficrespijb); */
                   10769:   
                   10770:   return 0;
1.217     brouard  10771: }
1.218     brouard  10772:  
1.180     brouard  10773: int hPijx(double *p, int bage, int fage){
                   10774:     /*------------- h Pij x at various ages ------------*/
                   10775: 
                   10776:   int stepsize;
                   10777:   int agelim;
                   10778:   int hstepm;
                   10779:   int nhstepm;
1.235     brouard  10780:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10781: 
                   10782:   double agedeb;
                   10783:   double ***p3mat;
                   10784: 
1.201     brouard  10785:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10786:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10787:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10788:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10789:     }
                   10790:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10791:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10792:   
                   10793:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10794:     /*if (stepm<=24) stepsize=2;*/
                   10795: 
                   10796:     agelim=AGESUP;
                   10797:     hstepm=stepsize*YEARM; /* Every year of age */
                   10798:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10799:                
1.180     brouard  10800:     /* hstepm=1;   aff par mois*/
                   10801:     pstamp(ficrespij);
                   10802:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10803:     i1= pow(2,cptcoveff);
1.218     brouard  10804:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10805:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10806:                /*      k=k+1;  */
1.235     brouard  10807:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10808:     for(k=1; k<=i1;k++){
1.253     brouard  10809:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10810:        continue;
1.183     brouard  10811:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10812:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10813:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10814:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10815:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10816:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10817:       }
1.183     brouard  10818:       fprintf(ficrespij,"******\n");
                   10819:       
                   10820:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10821:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10822:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10823:        
                   10824:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10825:        
1.183     brouard  10826:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10827:        oldm=oldms;savm=savms;
1.235     brouard  10828:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10829:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10830:        for(i=1; i<=nlstate;i++)
                   10831:          for(j=1; j<=nlstate+ndeath;j++)
                   10832:            fprintf(ficrespij," %1d-%1d",i,j);
                   10833:        fprintf(ficrespij,"\n");
                   10834:        for (h=0; h<=nhstepm; h++){
                   10835:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10836:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10837:          for(i=1; i<=nlstate;i++)
                   10838:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10839:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10840:          fprintf(ficrespij,"\n");
                   10841:        }
1.183     brouard  10842:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10843:        fprintf(ficrespij,"\n");
                   10844:       }
1.180     brouard  10845:       /*}*/
                   10846:     }
1.218     brouard  10847:     return 0;
1.180     brouard  10848: }
1.218     brouard  10849:  
                   10850:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10851:     /*------------- h Bij x at various ages ------------*/
                   10852: 
                   10853:   int stepsize;
1.218     brouard  10854:   /* int agelim; */
                   10855:        int ageminl;
1.217     brouard  10856:   int hstepm;
                   10857:   int nhstepm;
1.238     brouard  10858:   int h, i, i1, j, k, nres;
1.218     brouard  10859:        
1.217     brouard  10860:   double agedeb;
                   10861:   double ***p3mat;
1.218     brouard  10862:        
                   10863:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10864:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10865:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10866:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10867:   }
                   10868:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10869:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10870:   
                   10871:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10872:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10873:   
1.218     brouard  10874:   /* agelim=AGESUP; */
1.289     brouard  10875:   ageminl=AGEINF; /* was 30 */
1.218     brouard  10876:   hstepm=stepsize*YEARM; /* Every year of age */
                   10877:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10878:   
                   10879:   /* hstepm=1;   aff par mois*/
                   10880:   pstamp(ficrespijb);
1.255     brouard  10881:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10882:   i1= pow(2,cptcoveff);
1.218     brouard  10883:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10884:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10885:   /*   k=k+1;  */
1.238     brouard  10886:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10887:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10888:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10889:        continue;
                   10890:       fprintf(ficrespijb,"\n#****** ");
                   10891:       for(j=1;j<=cptcoveff;j++)
                   10892:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10893:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10894:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10895:       }
                   10896:       fprintf(ficrespijb,"******\n");
1.264     brouard  10897:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10898:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10899:        continue;
                   10900:       }
                   10901:       
                   10902:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10903:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10904:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
1.297     brouard  10905:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm+0.1)-1; /* Typically 20 years = 20*12/6=40 or 55*12/24=27.5-1.1=>27 */
                   10906:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 or 28*/
1.238     brouard  10907:        
                   10908:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10909:        
1.266     brouard  10910:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10911:        /* and memory limitations if stepm is small */
                   10912: 
1.238     brouard  10913:        /* oldm=oldms;savm=savms; */
                   10914:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10915:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10916:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10917:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10918:        for(i=1; i<=nlstate;i++)
                   10919:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10920:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10921:        fprintf(ficrespijb,"\n");
1.238     brouard  10922:        for (h=0; h<=nhstepm; h++){
                   10923:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10924:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10925:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10926:          for(i=1; i<=nlstate;i++)
                   10927:            for(j=1; j<=nlstate+ndeath;j++)
                   10928:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10929:          fprintf(ficrespijb,"\n");
                   10930:        }
                   10931:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10932:        fprintf(ficrespijb,"\n");
                   10933:       } /* end age deb */
                   10934:     } /* end combination */
                   10935:   } /* end nres */
1.218     brouard  10936:   return 0;
                   10937:  } /*  hBijx */
1.217     brouard  10938: 
1.180     brouard  10939: 
1.136     brouard  10940: /***********************************************/
                   10941: /**************** Main Program *****************/
                   10942: /***********************************************/
                   10943: 
                   10944: int main(int argc, char *argv[])
                   10945: {
                   10946: #ifdef GSL
                   10947:   const gsl_multimin_fminimizer_type *T;
                   10948:   size_t iteri = 0, it;
                   10949:   int rval = GSL_CONTINUE;
                   10950:   int status = GSL_SUCCESS;
                   10951:   double ssval;
                   10952: #endif
                   10953:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  10954:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   10955:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  10956:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10957:   int jj, ll, li, lj, lk;
1.136     brouard  10958:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10959:   int num_filled;
1.136     brouard  10960:   int itimes;
                   10961:   int NDIM=2;
                   10962:   int vpopbased=0;
1.235     brouard  10963:   int nres=0;
1.258     brouard  10964:   int endishere=0;
1.277     brouard  10965:   int noffset=0;
1.274     brouard  10966:   int ncurrv=0; /* Temporary variable */
                   10967:   
1.164     brouard  10968:   char ca[32], cb[32];
1.136     brouard  10969:   /*  FILE *fichtm; *//* Html File */
                   10970:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10971:   struct stat info;
1.191     brouard  10972:   double agedeb=0.;
1.194     brouard  10973: 
                   10974:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10975:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10976: 
1.165     brouard  10977:   double fret;
1.191     brouard  10978:   double dum=0.; /* Dummy variable */
1.136     brouard  10979:   double ***p3mat;
1.218     brouard  10980:   /* double ***mobaverage; */
1.164     brouard  10981: 
                   10982:   char line[MAXLINE];
1.197     brouard  10983:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10984: 
1.234     brouard  10985:   char  modeltemp[MAXLINE];
1.230     brouard  10986:   char resultline[MAXLINE];
                   10987:   
1.136     brouard  10988:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10989:   char *tok, *val; /* pathtot */
1.290     brouard  10990:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  10991:   int c,  h , cpt, c2;
1.191     brouard  10992:   int jl=0;
                   10993:   int i1, j1, jk, stepsize=0;
1.194     brouard  10994:   int count=0;
                   10995: 
1.164     brouard  10996:   int *tab; 
1.136     brouard  10997:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.296     brouard  10998:   /* double anprojd, mprojd, jprojd; /\* For eventual projections *\/ */
                   10999:   /* double anprojf, mprojf, jprojf; */
                   11000:   /* double jintmean,mintmean,aintmean;   */
                   11001:   int prvforecast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11002:   int prvbackcast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11003:   double yrfproj= 10.0; /* Number of years of forward projections */
                   11004:   double yrbproj= 10.0; /* Number of years of backward projections */
                   11005:   int prevbcast=0; /* defined as global for mlikeli and mle, replacing backcast */
1.136     brouard  11006:   int mobilav=0,popforecast=0;
1.191     brouard  11007:   int hstepm=0, nhstepm=0;
1.136     brouard  11008:   int agemortsup;
                   11009:   float  sumlpop=0.;
                   11010:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   11011:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   11012: 
1.191     brouard  11013:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  11014:   double ftolpl=FTOL;
                   11015:   double **prlim;
1.217     brouard  11016:   double **bprlim;
1.136     brouard  11017:   double ***param; /* Matrix of parameters */
1.251     brouard  11018:   double ***paramstart; /* Matrix of starting parameter values */
                   11019:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  11020:   double **matcov; /* Matrix of covariance */
1.203     brouard  11021:   double **hess; /* Hessian matrix */
1.136     brouard  11022:   double ***delti3; /* Scale */
                   11023:   double *delti; /* Scale */
                   11024:   double ***eij, ***vareij;
                   11025:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  11026: 
1.136     brouard  11027:   double *epj, vepp;
1.164     brouard  11028: 
1.273     brouard  11029:   double dateprev1, dateprev2;
1.296     brouard  11030:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0, dateprojd=0, dateprojf=0;
                   11031:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0, datebackd=0, datebackf=0;
                   11032: 
1.217     brouard  11033: 
1.136     brouard  11034:   double **ximort;
1.145     brouard  11035:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  11036:   int *dcwave;
                   11037: 
1.164     brouard  11038:   char z[1]="c";
1.136     brouard  11039: 
                   11040:   /*char  *strt;*/
                   11041:   char strtend[80];
1.126     brouard  11042: 
1.164     brouard  11043: 
1.126     brouard  11044: /*   setlocale (LC_ALL, ""); */
                   11045: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   11046: /*   textdomain (PACKAGE); */
                   11047: /*   setlocale (LC_CTYPE, ""); */
                   11048: /*   setlocale (LC_MESSAGES, ""); */
                   11049: 
                   11050:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  11051:   rstart_time = time(NULL);  
                   11052:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   11053:   start_time = *localtime(&rstart_time);
1.126     brouard  11054:   curr_time=start_time;
1.157     brouard  11055:   /*tml = *localtime(&start_time.tm_sec);*/
                   11056:   /* strcpy(strstart,asctime(&tml)); */
                   11057:   strcpy(strstart,asctime(&start_time));
1.126     brouard  11058: 
                   11059: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  11060: /*  tp.tm_sec = tp.tm_sec +86400; */
                   11061: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  11062: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   11063: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   11064: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  11065: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  11066: /*   strt=asctime(&tmg); */
                   11067: /*   printf("Time(after) =%s",strstart);  */
                   11068: /*  (void) time (&time_value);
                   11069: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   11070: *  tm = *localtime(&time_value);
                   11071: *  strstart=asctime(&tm);
                   11072: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   11073: */
                   11074: 
                   11075:   nberr=0; /* Number of errors and warnings */
                   11076:   nbwarn=0;
1.184     brouard  11077: #ifdef WIN32
                   11078:   _getcwd(pathcd, size);
                   11079: #else
1.126     brouard  11080:   getcwd(pathcd, size);
1.184     brouard  11081: #endif
1.191     brouard  11082:   syscompilerinfo(0);
1.196     brouard  11083:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  11084:   if(argc <=1){
                   11085:     printf("\nEnter the parameter file name: ");
1.205     brouard  11086:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   11087:       printf("ERROR Empty parameter file name\n");
                   11088:       goto end;
                   11089:     }
1.126     brouard  11090:     i=strlen(pathr);
                   11091:     if(pathr[i-1]=='\n')
                   11092:       pathr[i-1]='\0';
1.156     brouard  11093:     i=strlen(pathr);
1.205     brouard  11094:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  11095:       pathr[i-1]='\0';
1.205     brouard  11096:     }
                   11097:     i=strlen(pathr);
                   11098:     if( i==0 ){
                   11099:       printf("ERROR Empty parameter file name\n");
                   11100:       goto end;
                   11101:     }
                   11102:     for (tok = pathr; tok != NULL; ){
1.126     brouard  11103:       printf("Pathr |%s|\n",pathr);
                   11104:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   11105:       printf("val= |%s| pathr=%s\n",val,pathr);
                   11106:       strcpy (pathtot, val);
                   11107:       if(pathr[0] == '\0') break; /* Dirty */
                   11108:     }
                   11109:   }
1.281     brouard  11110:   else if (argc<=2){
                   11111:     strcpy(pathtot,argv[1]);
                   11112:   }
1.126     brouard  11113:   else{
                   11114:     strcpy(pathtot,argv[1]);
1.281     brouard  11115:     strcpy(z,argv[2]);
                   11116:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  11117:   }
                   11118:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   11119:   /*cygwin_split_path(pathtot,path,optionfile);
                   11120:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   11121:   /* cutv(path,optionfile,pathtot,'\\');*/
                   11122: 
                   11123:   /* Split argv[0], imach program to get pathimach */
                   11124:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   11125:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11126:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11127:  /*   strcpy(pathimach,argv[0]); */
                   11128:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   11129:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   11130:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  11131: #ifdef WIN32
                   11132:   _chdir(path); /* Can be a relative path */
                   11133:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   11134: #else
1.126     brouard  11135:   chdir(path); /* Can be a relative path */
1.184     brouard  11136:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   11137: #endif
                   11138:   printf("Current directory %s!\n",pathcd);
1.126     brouard  11139:   strcpy(command,"mkdir ");
                   11140:   strcat(command,optionfilefiname);
                   11141:   if((outcmd=system(command)) != 0){
1.169     brouard  11142:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  11143:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   11144:     /* fclose(ficlog); */
                   11145: /*     exit(1); */
                   11146:   }
                   11147: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   11148: /*     perror("mkdir"); */
                   11149: /*   } */
                   11150: 
                   11151:   /*-------- arguments in the command line --------*/
                   11152: 
1.186     brouard  11153:   /* Main Log file */
1.126     brouard  11154:   strcat(filelog, optionfilefiname);
                   11155:   strcat(filelog,".log");    /* */
                   11156:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   11157:     printf("Problem with logfile %s\n",filelog);
                   11158:     goto end;
                   11159:   }
                   11160:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  11161:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  11162:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   11163:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   11164:  path=%s \n\
                   11165:  optionfile=%s\n\
                   11166:  optionfilext=%s\n\
1.156     brouard  11167:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  11168: 
1.197     brouard  11169:   syscompilerinfo(1);
1.167     brouard  11170: 
1.126     brouard  11171:   printf("Local time (at start):%s",strstart);
                   11172:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   11173:   fflush(ficlog);
                   11174: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  11175: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  11176: 
                   11177:   /* */
                   11178:   strcpy(fileres,"r");
                   11179:   strcat(fileres, optionfilefiname);
1.201     brouard  11180:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  11181:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  11182:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  11183: 
1.186     brouard  11184:   /* Main ---------arguments file --------*/
1.126     brouard  11185: 
                   11186:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  11187:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   11188:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  11189:     fflush(ficlog);
1.149     brouard  11190:     /* goto end; */
                   11191:     exit(70); 
1.126     brouard  11192:   }
                   11193: 
                   11194:   strcpy(filereso,"o");
1.201     brouard  11195:   strcat(filereso,fileresu);
1.126     brouard  11196:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   11197:     printf("Problem with Output resultfile: %s\n", filereso);
                   11198:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   11199:     fflush(ficlog);
                   11200:     goto end;
                   11201:   }
1.278     brouard  11202:       /*-------- Rewriting parameter file ----------*/
                   11203:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   11204:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   11205:   strcat(rfileres,".");    /* */
                   11206:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11207:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   11208:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11209:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   11210:     fflush(ficlog);
                   11211:     goto end;
                   11212:   }
                   11213:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  11214: 
1.278     brouard  11215:                                      
1.126     brouard  11216:   /* Reads comments: lines beginning with '#' */
                   11217:   numlinepar=0;
1.277     brouard  11218:   /* Is it a BOM UTF-8 Windows file? */
                   11219:   /* First parameter line */
1.197     brouard  11220:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  11221:     noffset=0;
                   11222:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   11223:     {
                   11224:       noffset=noffset+3;
                   11225:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11226:     }
1.302     brouard  11227: /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   11228:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
1.277     brouard  11229:     {
                   11230:       noffset=noffset+2;
                   11231:       printf("# File is an UTF16BE BOM file\n");
                   11232:     }
                   11233:     else if( line[0] == 0 && line[1] == 0)
                   11234:     {
                   11235:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11236:        noffset=noffset+4;
                   11237:        printf("# File is an UTF16BE BOM file\n");
                   11238:       }
                   11239:     } else{
                   11240:       ;/*printf(" Not a BOM file\n");*/
                   11241:     }
                   11242:   
1.197     brouard  11243:     /* If line starts with a # it is a comment */
1.277     brouard  11244:     if (line[noffset] == '#') {
1.197     brouard  11245:       numlinepar++;
                   11246:       fputs(line,stdout);
                   11247:       fputs(line,ficparo);
1.278     brouard  11248:       fputs(line,ficres);
1.197     brouard  11249:       fputs(line,ficlog);
                   11250:       continue;
                   11251:     }else
                   11252:       break;
                   11253:   }
                   11254:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11255:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11256:     if (num_filled != 5) {
                   11257:       printf("Should be 5 parameters\n");
1.283     brouard  11258:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11259:     }
1.126     brouard  11260:     numlinepar++;
1.197     brouard  11261:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11262:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11263:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11264:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11265:   }
                   11266:   /* Second parameter line */
                   11267:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11268:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11269:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11270:     if (line[0] == '#') {
                   11271:       numlinepar++;
1.283     brouard  11272:       printf("%s",line);
                   11273:       fprintf(ficres,"%s",line);
                   11274:       fprintf(ficparo,"%s",line);
                   11275:       fprintf(ficlog,"%s",line);
1.197     brouard  11276:       continue;
                   11277:     }else
                   11278:       break;
                   11279:   }
1.223     brouard  11280:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11281:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11282:     if (num_filled != 11) {
                   11283:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11284:       printf("but line=%s\n",line);
1.283     brouard  11285:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11286:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11287:     }
1.286     brouard  11288:     if( lastpass > maxwav){
                   11289:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11290:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11291:       fflush(ficlog);
                   11292:       goto end;
                   11293:     }
                   11294:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11295:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11296:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11297:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11298:   }
1.203     brouard  11299:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11300:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11301:   /* Third parameter line */
                   11302:   while(fgets(line, MAXLINE, ficpar)) {
                   11303:     /* If line starts with a # it is a comment */
                   11304:     if (line[0] == '#') {
                   11305:       numlinepar++;
1.283     brouard  11306:       printf("%s",line);
                   11307:       fprintf(ficres,"%s",line);
                   11308:       fprintf(ficparo,"%s",line);
                   11309:       fprintf(ficlog,"%s",line);
1.197     brouard  11310:       continue;
                   11311:     }else
                   11312:       break;
                   11313:   }
1.201     brouard  11314:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11315:     if (num_filled != 1){
1.302     brouard  11316:       printf("ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
                   11317:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
1.197     brouard  11318:       model[0]='\0';
                   11319:       goto end;
                   11320:     }
                   11321:     else{
                   11322:       if (model[0]=='+'){
                   11323:        for(i=1; i<=strlen(model);i++)
                   11324:          modeltemp[i-1]=model[i];
1.201     brouard  11325:        strcpy(model,modeltemp); 
1.197     brouard  11326:       }
                   11327:     }
1.199     brouard  11328:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11329:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11330:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11331:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11332:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11333:   }
                   11334:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11335:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11336:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11337:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11338:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11339:   fflush(ficlog);
1.190     brouard  11340:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11341:   if(model[0]=='#'){
1.279     brouard  11342:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11343:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11344:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11345:     if(mle != -1){
1.279     brouard  11346:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11347:       exit(1);
                   11348:     }
                   11349:   }
1.126     brouard  11350:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11351:     ungetc(c,ficpar);
                   11352:     fgets(line, MAXLINE, ficpar);
                   11353:     numlinepar++;
1.195     brouard  11354:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11355:       z[0]=line[1];
                   11356:     }
                   11357:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11358:     fputs(line, stdout);
                   11359:     //puts(line);
1.126     brouard  11360:     fputs(line,ficparo);
                   11361:     fputs(line,ficlog);
                   11362:   }
                   11363:   ungetc(c,ficpar);
                   11364: 
                   11365:    
1.290     brouard  11366:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11367:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11368:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11369:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11370:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11371:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11372:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11373:   */
                   11374:   if (strlen(model)>1) 
1.187     brouard  11375:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11376:   else
1.187     brouard  11377:     ncovmodel=2; /* Constant and age */
1.133     brouard  11378:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11379:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11380:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11381:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11382:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11383:     fflush(stdout);
                   11384:     fclose (ficlog);
                   11385:     goto end;
                   11386:   }
1.126     brouard  11387:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11388:   delti=delti3[1][1];
                   11389:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11390:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11391: /* We could also provide initial parameters values giving by simple logistic regression 
                   11392:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11393:       /* for(i=1;i<nlstate;i++){ */
                   11394:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11395:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11396:       /* } */
1.126     brouard  11397:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11398:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11399:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11400:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11401:     fclose (ficparo);
                   11402:     fclose (ficlog);
                   11403:     goto end;
                   11404:     exit(0);
1.220     brouard  11405:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11406:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11407:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11408:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11409:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11410:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11411:     hess=matrix(1,npar,1,npar);
1.220     brouard  11412:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11413:     /* Read guessed parameters */
1.126     brouard  11414:     /* Reads comments: lines beginning with '#' */
                   11415:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11416:       ungetc(c,ficpar);
                   11417:       fgets(line, MAXLINE, ficpar);
                   11418:       numlinepar++;
1.141     brouard  11419:       fputs(line,stdout);
1.126     brouard  11420:       fputs(line,ficparo);
                   11421:       fputs(line,ficlog);
                   11422:     }
                   11423:     ungetc(c,ficpar);
                   11424:     
                   11425:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11426:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11427:     for(i=1; i <=nlstate; i++){
1.234     brouard  11428:       j=0;
1.126     brouard  11429:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11430:        if(jj==i) continue;
                   11431:        j++;
1.292     brouard  11432:        while((c=getc(ficpar))=='#' && c!= EOF){
                   11433:          ungetc(c,ficpar);
                   11434:          fgets(line, MAXLINE, ficpar);
                   11435:          numlinepar++;
                   11436:          fputs(line,stdout);
                   11437:          fputs(line,ficparo);
                   11438:          fputs(line,ficlog);
                   11439:        }
                   11440:        ungetc(c,ficpar);
1.234     brouard  11441:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11442:        if ((i1 != i) || (j1 != jj)){
                   11443:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11444: It might be a problem of design; if ncovcol and the model are correct\n \
                   11445: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11446:          exit(1);
                   11447:        }
                   11448:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11449:        if(mle==1)
                   11450:          printf("%1d%1d",i,jj);
                   11451:        fprintf(ficlog,"%1d%1d",i,jj);
                   11452:        for(k=1; k<=ncovmodel;k++){
                   11453:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11454:          if(mle==1){
                   11455:            printf(" %lf",param[i][j][k]);
                   11456:            fprintf(ficlog," %lf",param[i][j][k]);
                   11457:          }
                   11458:          else
                   11459:            fprintf(ficlog," %lf",param[i][j][k]);
                   11460:          fprintf(ficparo," %lf",param[i][j][k]);
                   11461:        }
                   11462:        fscanf(ficpar,"\n");
                   11463:        numlinepar++;
                   11464:        if(mle==1)
                   11465:          printf("\n");
                   11466:        fprintf(ficlog,"\n");
                   11467:        fprintf(ficparo,"\n");
1.126     brouard  11468:       }
                   11469:     }  
                   11470:     fflush(ficlog);
1.234     brouard  11471:     
1.251     brouard  11472:     /* Reads parameters values */
1.126     brouard  11473:     p=param[1][1];
1.251     brouard  11474:     pstart=paramstart[1][1];
1.126     brouard  11475:     
                   11476:     /* Reads comments: lines beginning with '#' */
                   11477:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11478:       ungetc(c,ficpar);
                   11479:       fgets(line, MAXLINE, ficpar);
                   11480:       numlinepar++;
1.141     brouard  11481:       fputs(line,stdout);
1.126     brouard  11482:       fputs(line,ficparo);
                   11483:       fputs(line,ficlog);
                   11484:     }
                   11485:     ungetc(c,ficpar);
                   11486: 
                   11487:     for(i=1; i <=nlstate; i++){
                   11488:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11489:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11490:        if ( (i1-i) * (j1-j) != 0){
                   11491:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11492:          exit(1);
                   11493:        }
                   11494:        printf("%1d%1d",i,j);
                   11495:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11496:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11497:        for(k=1; k<=ncovmodel;k++){
                   11498:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11499:          printf(" %le",delti3[i][j][k]);
                   11500:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11501:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11502:        }
                   11503:        fscanf(ficpar,"\n");
                   11504:        numlinepar++;
                   11505:        printf("\n");
                   11506:        fprintf(ficparo,"\n");
                   11507:        fprintf(ficlog,"\n");
1.126     brouard  11508:       }
                   11509:     }
                   11510:     fflush(ficlog);
1.234     brouard  11511:     
1.145     brouard  11512:     /* Reads covariance matrix */
1.126     brouard  11513:     delti=delti3[1][1];
1.220     brouard  11514:                
                   11515:                
1.126     brouard  11516:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11517:                
1.126     brouard  11518:     /* Reads comments: lines beginning with '#' */
                   11519:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11520:       ungetc(c,ficpar);
                   11521:       fgets(line, MAXLINE, ficpar);
                   11522:       numlinepar++;
1.141     brouard  11523:       fputs(line,stdout);
1.126     brouard  11524:       fputs(line,ficparo);
                   11525:       fputs(line,ficlog);
                   11526:     }
                   11527:     ungetc(c,ficpar);
1.220     brouard  11528:                
1.126     brouard  11529:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11530:     hess=matrix(1,npar,1,npar);
1.131     brouard  11531:     for(i=1; i <=npar; i++)
                   11532:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11533:                
1.194     brouard  11534:     /* Scans npar lines */
1.126     brouard  11535:     for(i=1; i <=npar; i++){
1.226     brouard  11536:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11537:       if(count != 3){
1.226     brouard  11538:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11539: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11540: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11541:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11542: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11543: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11544:        exit(1);
1.220     brouard  11545:       }else{
1.226     brouard  11546:        if(mle==1)
                   11547:          printf("%1d%1d%d",i1,j1,jk);
                   11548:       }
                   11549:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11550:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11551:       for(j=1; j <=i; j++){
1.226     brouard  11552:        fscanf(ficpar," %le",&matcov[i][j]);
                   11553:        if(mle==1){
                   11554:          printf(" %.5le",matcov[i][j]);
                   11555:        }
                   11556:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11557:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11558:       }
                   11559:       fscanf(ficpar,"\n");
                   11560:       numlinepar++;
                   11561:       if(mle==1)
1.220     brouard  11562:                                printf("\n");
1.126     brouard  11563:       fprintf(ficlog,"\n");
                   11564:       fprintf(ficparo,"\n");
                   11565:     }
1.194     brouard  11566:     /* End of read covariance matrix npar lines */
1.126     brouard  11567:     for(i=1; i <=npar; i++)
                   11568:       for(j=i+1;j<=npar;j++)
1.226     brouard  11569:        matcov[i][j]=matcov[j][i];
1.126     brouard  11570:     
                   11571:     if(mle==1)
                   11572:       printf("\n");
                   11573:     fprintf(ficlog,"\n");
                   11574:     
                   11575:     fflush(ficlog);
                   11576:     
                   11577:   }    /* End of mle != -3 */
1.218     brouard  11578:   
1.186     brouard  11579:   /*  Main data
                   11580:    */
1.290     brouard  11581:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11582:   /* num=lvector(1,n); */
                   11583:   /* moisnais=vector(1,n); */
                   11584:   /* annais=vector(1,n); */
                   11585:   /* moisdc=vector(1,n); */
                   11586:   /* andc=vector(1,n); */
                   11587:   /* weight=vector(1,n); */
                   11588:   /* agedc=vector(1,n); */
                   11589:   /* cod=ivector(1,n); */
                   11590:   /* for(i=1;i<=n;i++){ */
                   11591:   num=lvector(firstobs,lastobs);
                   11592:   moisnais=vector(firstobs,lastobs);
                   11593:   annais=vector(firstobs,lastobs);
                   11594:   moisdc=vector(firstobs,lastobs);
                   11595:   andc=vector(firstobs,lastobs);
                   11596:   weight=vector(firstobs,lastobs);
                   11597:   agedc=vector(firstobs,lastobs);
                   11598:   cod=ivector(firstobs,lastobs);
                   11599:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11600:     num[i]=0;
                   11601:     moisnais[i]=0;
                   11602:     annais[i]=0;
                   11603:     moisdc[i]=0;
                   11604:     andc[i]=0;
                   11605:     agedc[i]=0;
                   11606:     cod[i]=0;
                   11607:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11608:   }
1.290     brouard  11609:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11610:   anint=matrix(1,maxwav,firstobs,lastobs);
                   11611:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11612:   tab=ivector(1,NCOVMAX);
1.144     brouard  11613:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11614:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11615: 
1.136     brouard  11616:   /* Reads data from file datafile */
                   11617:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11618:     goto end;
                   11619: 
                   11620:   /* Calculation of the number of parameters from char model */
1.234     brouard  11621:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11622:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11623:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11624:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11625:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11626:   */
                   11627:   
                   11628:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11629:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11630:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11631:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11632:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11633:   TvarF=ivector(1,NCOVMAX); /*  */
                   11634:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11635:   TvarV=ivector(1,NCOVMAX); /*  */
                   11636:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11637:   TvarA=ivector(1,NCOVMAX); /*  */
                   11638:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11639:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11640:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11641:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11642:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11643:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11644:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11645:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11646:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11647: 
1.230     brouard  11648:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11649:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11650:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11651:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11652:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11653:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11654:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11655:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11656:   */
                   11657:   /* For model-covariate k tells which data-covariate to use but
                   11658:     because this model-covariate is a construction we invent a new column
                   11659:     ncovcol + k1
                   11660:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11661:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11662:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11663:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11664:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11665:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11666:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11667:   */
1.145     brouard  11668:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11669:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11670:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11671:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11672:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11673:                         4 covariates (3 plus signs)
                   11674:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11675:                      */  
1.230     brouard  11676:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11677:                                * individual dummy, fixed or varying:
                   11678:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11679:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11680:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11681:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11682:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11683:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11684:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11685:                                * individual quantitative, fixed or varying:
                   11686:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11687:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11688:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11689: /* Main decodemodel */
                   11690: 
1.187     brouard  11691: 
1.223     brouard  11692:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11693:     goto end;
                   11694: 
1.137     brouard  11695:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11696:     nbwarn++;
                   11697:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11698:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11699:   }
1.136     brouard  11700:     /*  if(mle==1){*/
1.137     brouard  11701:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11702:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11703:   }
                   11704: 
                   11705:     /*-calculation of age at interview from date of interview and age at death -*/
                   11706:   agev=matrix(1,maxwav,1,imx);
                   11707: 
                   11708:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11709:     goto end;
                   11710: 
1.126     brouard  11711: 
1.136     brouard  11712:   agegomp=(int)agemin;
1.290     brouard  11713:   free_vector(moisnais,firstobs,lastobs);
                   11714:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11715:   /* free_matrix(mint,1,maxwav,1,n);
                   11716:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11717:   /* free_vector(moisdc,1,n); */
                   11718:   /* free_vector(andc,1,n); */
1.145     brouard  11719:   /* */
                   11720:   
1.126     brouard  11721:   wav=ivector(1,imx);
1.214     brouard  11722:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11723:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11724:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11725:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11726:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11727:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11728:    
                   11729:   /* Concatenates waves */
1.214     brouard  11730:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11731:      Death is a valid wave (if date is known).
                   11732:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11733:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11734:      and mw[mi+1][i]. dh depends on stepm.
                   11735:   */
                   11736: 
1.126     brouard  11737:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11738:   /* Concatenates waves */
1.145     brouard  11739:  
1.290     brouard  11740:   free_vector(moisdc,firstobs,lastobs);
                   11741:   free_vector(andc,firstobs,lastobs);
1.215     brouard  11742: 
1.126     brouard  11743:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11744:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11745:   ncodemax[1]=1;
1.145     brouard  11746:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11747:   cptcoveff=0;
1.220     brouard  11748:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11749:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11750:   }
                   11751:   
                   11752:   ncovcombmax=pow(2,cptcoveff);
                   11753:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11754:   for(i=1;i<ncovcombmax;i++)
                   11755:     invalidvarcomb[i]=0;
                   11756:   
1.211     brouard  11757:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11758:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11759:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11760:   
1.200     brouard  11761:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11762:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11763:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11764:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11765:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11766:    * (currently 0 or 1) in the data.
                   11767:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11768:    * corresponding modality (h,j).
                   11769:    */
                   11770: 
1.145     brouard  11771:   h=0;
                   11772:   /*if (cptcovn > 0) */
1.126     brouard  11773:   m=pow(2,cptcoveff);
                   11774:  
1.144     brouard  11775:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11776:           * For k=4 covariates, h goes from 1 to m=2**k
                   11777:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11778:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11779:           *     h\k   1     2     3     4
1.143     brouard  11780:           *______________________________  
                   11781:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11782:           *     2     2     1     1     1
                   11783:           *     3 i=2 1     2     1     1
                   11784:           *     4     2     2     1     1
                   11785:           *     5 i=3 1 i=2 1     2     1
                   11786:           *     6     2     1     2     1
                   11787:           *     7 i=4 1     2     2     1
                   11788:           *     8     2     2     2     1
1.197     brouard  11789:           *     9 i=5 1 i=3 1 i=2 1     2
                   11790:           *    10     2     1     1     2
                   11791:           *    11 i=6 1     2     1     2
                   11792:           *    12     2     2     1     2
                   11793:           *    13 i=7 1 i=4 1     2     2    
                   11794:           *    14     2     1     2     2
                   11795:           *    15 i=8 1     2     2     2
                   11796:           *    16     2     2     2     2
1.143     brouard  11797:           */
1.212     brouard  11798:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11799:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11800:      * and the value of each covariate?
                   11801:      * V1=1, V2=1, V3=2, V4=1 ?
                   11802:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11803:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11804:      * In order to get the real value in the data, we use nbcode
                   11805:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11806:      * We are keeping this crazy system in order to be able (in the future?) 
                   11807:      * to have more than 2 values (0 or 1) for a covariate.
                   11808:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11809:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11810:      *              bbbbbbbb
                   11811:      *              76543210     
                   11812:      *   h-1        00000101 (6-1=5)
1.219     brouard  11813:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11814:      *           &
                   11815:      *     1        00000001 (1)
1.219     brouard  11816:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11817:      *          +1= 00000001 =1 
1.211     brouard  11818:      *
                   11819:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11820:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11821:      *    >>k'            11
                   11822:      *          &   00000001
                   11823:      *            = 00000001
                   11824:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11825:      * Reverse h=6 and m=16?
                   11826:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11827:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11828:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11829:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11830:      * V3=decodtabm(14,3,2**4)=2
                   11831:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11832:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11833:      *          &1 000000001
                   11834:      *           = 000000001
                   11835:      *         +1= 000000010 =2
                   11836:      *                  2211
                   11837:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11838:      *                  V3=2
1.220     brouard  11839:                 * codtabm and decodtabm are identical
1.211     brouard  11840:      */
                   11841: 
1.145     brouard  11842: 
                   11843:  free_ivector(Ndum,-1,NCOVMAX);
                   11844: 
                   11845: 
1.126     brouard  11846:     
1.186     brouard  11847:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11848:   strcpy(optionfilegnuplot,optionfilefiname);
                   11849:   if(mle==-3)
1.201     brouard  11850:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11851:   strcat(optionfilegnuplot,".gp");
                   11852: 
                   11853:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11854:     printf("Problem with file %s",optionfilegnuplot);
                   11855:   }
                   11856:   else{
1.204     brouard  11857:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11858:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11859:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11860:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11861:   }
                   11862:   /*  fclose(ficgp);*/
1.186     brouard  11863: 
                   11864: 
                   11865:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11866: 
                   11867:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11868:   if(mle==-3)
1.201     brouard  11869:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11870:   strcat(optionfilehtm,".htm");
                   11871:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11872:     printf("Problem with %s \n",optionfilehtm);
                   11873:     exit(0);
1.126     brouard  11874:   }
                   11875: 
                   11876:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11877:   strcat(optionfilehtmcov,"-cov.htm");
                   11878:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11879:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11880:   }
                   11881:   else{
                   11882:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11883: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11884: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11885:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11886:   }
                   11887: 
1.213     brouard  11888:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11889: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11890: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11891: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11892: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11893: \n\
                   11894: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11895:  <ul><li><h4>Parameter files</h4>\n\
                   11896:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11897:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11898:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11899:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11900:  - Date and time at start: %s</ul>\n",\
                   11901:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11902:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11903:          fileres,fileres,\
                   11904:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11905:   fflush(fichtm);
                   11906: 
                   11907:   strcpy(pathr,path);
                   11908:   strcat(pathr,optionfilefiname);
1.184     brouard  11909: #ifdef WIN32
                   11910:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11911: #else
1.126     brouard  11912:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11913: #endif
                   11914:          
1.126     brouard  11915:   
1.220     brouard  11916:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11917:                 and for any valid combination of covariates
1.126     brouard  11918:      and prints on file fileres'p'. */
1.251     brouard  11919:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11920:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11921: 
                   11922:   fprintf(fichtm,"\n");
1.286     brouard  11923:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  11924:          ftol, stepm);
                   11925:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11926:   ncurrv=1;
                   11927:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11928:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11929:   ncurrv=i;
                   11930:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11931:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  11932:   ncurrv=i;
                   11933:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11934:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  11935:   ncurrv=i;
                   11936:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11937:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11938:           nlstate, ndeath, maxwav, mle, weightopt);
                   11939: 
                   11940:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11941: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11942: 
                   11943:   
                   11944:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11945: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11946: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11947:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11948:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11949:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11950:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11951:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11952:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11953: 
1.126     brouard  11954:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11955:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11956:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11957: 
                   11958:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11959:   /* For mortality only */
1.126     brouard  11960:   if (mle==-3){
1.136     brouard  11961:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11962:     for(i=1;i<=NDIM;i++)
                   11963:       for(j=1;j<=NDIM;j++)
                   11964:        ximort[i][j]=0.;
1.186     brouard  11965:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  11966:     cens=ivector(firstobs,lastobs);
                   11967:     ageexmed=vector(firstobs,lastobs);
                   11968:     agecens=vector(firstobs,lastobs);
                   11969:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  11970:                
1.126     brouard  11971:     for (i=1; i<=imx; i++){
                   11972:       dcwave[i]=-1;
                   11973:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11974:        if (s[m][i]>nlstate) {
                   11975:          dcwave[i]=m;
                   11976:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11977:          break;
                   11978:        }
1.126     brouard  11979:     }
1.226     brouard  11980:     
1.126     brouard  11981:     for (i=1; i<=imx; i++) {
                   11982:       if (wav[i]>0){
1.226     brouard  11983:        ageexmed[i]=agev[mw[1][i]][i];
                   11984:        j=wav[i];
                   11985:        agecens[i]=1.; 
                   11986:        
                   11987:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11988:          agecens[i]=agev[mw[j][i]][i];
                   11989:          cens[i]= 1;
                   11990:        }else if (ageexmed[i]< 1) 
                   11991:          cens[i]= -1;
                   11992:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11993:          cens[i]=0 ;
1.126     brouard  11994:       }
                   11995:       else cens[i]=-1;
                   11996:     }
                   11997:     
                   11998:     for (i=1;i<=NDIM;i++) {
                   11999:       for (j=1;j<=NDIM;j++)
1.226     brouard  12000:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  12001:     }
                   12002:     
1.302     brouard  12003:     p[1]=0.0268; p[NDIM]=0.083;
                   12004:     /* printf("%lf %lf", p[1], p[2]); */
1.126     brouard  12005:     
                   12006:     
1.136     brouard  12007: #ifdef GSL
                   12008:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  12009: #else
1.126     brouard  12010:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  12011: #endif
1.201     brouard  12012:     strcpy(filerespow,"POW-MORT_"); 
                   12013:     strcat(filerespow,fileresu);
1.126     brouard  12014:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   12015:       printf("Problem with resultfile: %s\n", filerespow);
                   12016:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   12017:     }
1.136     brouard  12018: #ifdef GSL
                   12019:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  12020: #else
1.126     brouard  12021:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  12022: #endif
1.126     brouard  12023:     /*  for (i=1;i<=nlstate;i++)
                   12024:        for(j=1;j<=nlstate+ndeath;j++)
                   12025:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   12026:     */
                   12027:     fprintf(ficrespow,"\n");
1.136     brouard  12028: #ifdef GSL
                   12029:     /* gsl starts here */ 
                   12030:     T = gsl_multimin_fminimizer_nmsimplex;
                   12031:     gsl_multimin_fminimizer *sfm = NULL;
                   12032:     gsl_vector *ss, *x;
                   12033:     gsl_multimin_function minex_func;
                   12034: 
                   12035:     /* Initial vertex size vector */
                   12036:     ss = gsl_vector_alloc (NDIM);
                   12037:     
                   12038:     if (ss == NULL){
                   12039:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   12040:     }
                   12041:     /* Set all step sizes to 1 */
                   12042:     gsl_vector_set_all (ss, 0.001);
                   12043: 
                   12044:     /* Starting point */
1.126     brouard  12045:     
1.136     brouard  12046:     x = gsl_vector_alloc (NDIM);
                   12047:     
                   12048:     if (x == NULL){
                   12049:       gsl_vector_free(ss);
                   12050:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   12051:     }
                   12052:   
                   12053:     /* Initialize method and iterate */
                   12054:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  12055:     /*     gsl_vector_set(x, 0, 0.0268); */
                   12056:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  12057:     gsl_vector_set(x, 0, p[1]);
                   12058:     gsl_vector_set(x, 1, p[2]);
                   12059: 
                   12060:     minex_func.f = &gompertz_f;
                   12061:     minex_func.n = NDIM;
                   12062:     minex_func.params = (void *)&p; /* ??? */
                   12063:     
                   12064:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   12065:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   12066:     
                   12067:     printf("Iterations beginning .....\n\n");
                   12068:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   12069: 
                   12070:     iteri=0;
                   12071:     while (rval == GSL_CONTINUE){
                   12072:       iteri++;
                   12073:       status = gsl_multimin_fminimizer_iterate(sfm);
                   12074:       
                   12075:       if (status) printf("error: %s\n", gsl_strerror (status));
                   12076:       fflush(0);
                   12077:       
                   12078:       if (status) 
                   12079:         break;
                   12080:       
                   12081:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   12082:       ssval = gsl_multimin_fminimizer_size (sfm);
                   12083:       
                   12084:       if (rval == GSL_SUCCESS)
                   12085:         printf ("converged to a local maximum at\n");
                   12086:       
                   12087:       printf("%5d ", iteri);
                   12088:       for (it = 0; it < NDIM; it++){
                   12089:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   12090:       }
                   12091:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   12092:     }
                   12093:     
                   12094:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   12095:     
                   12096:     gsl_vector_free(x); /* initial values */
                   12097:     gsl_vector_free(ss); /* inital step size */
                   12098:     for (it=0; it<NDIM; it++){
                   12099:       p[it+1]=gsl_vector_get(sfm->x,it);
                   12100:       fprintf(ficrespow," %.12lf", p[it]);
                   12101:     }
                   12102:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   12103: #endif
                   12104: #ifdef POWELL
                   12105:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   12106: #endif  
1.126     brouard  12107:     fclose(ficrespow);
                   12108:     
1.203     brouard  12109:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  12110: 
                   12111:     for(i=1; i <=NDIM; i++)
                   12112:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  12113:                                matcov[i][j]=matcov[j][i];
1.126     brouard  12114:     
                   12115:     printf("\nCovariance matrix\n ");
1.203     brouard  12116:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  12117:     for(i=1; i <=NDIM; i++) {
                   12118:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  12119:                                printf("%f ",matcov[i][j]);
                   12120:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  12121:       }
1.203     brouard  12122:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  12123:     }
                   12124:     
                   12125:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  12126:     for (i=1;i<=NDIM;i++) {
1.126     brouard  12127:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  12128:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   12129:     }
1.302     brouard  12130:     lsurv=vector(agegomp,AGESUP);
                   12131:     lpop=vector(agegomp,AGESUP);
                   12132:     tpop=vector(agegomp,AGESUP);
1.126     brouard  12133:     lsurv[agegomp]=100000;
                   12134:     
                   12135:     for (k=agegomp;k<=AGESUP;k++) {
                   12136:       agemortsup=k;
                   12137:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   12138:     }
                   12139:     
                   12140:     for (k=agegomp;k<agemortsup;k++)
                   12141:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   12142:     
                   12143:     for (k=agegomp;k<agemortsup;k++){
                   12144:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   12145:       sumlpop=sumlpop+lpop[k];
                   12146:     }
                   12147:     
                   12148:     tpop[agegomp]=sumlpop;
                   12149:     for (k=agegomp;k<(agemortsup-3);k++){
                   12150:       /*  tpop[k+1]=2;*/
                   12151:       tpop[k+1]=tpop[k]-lpop[k];
                   12152:     }
                   12153:     
                   12154:     
                   12155:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   12156:     for (k=agegomp;k<(agemortsup-2);k++) 
                   12157:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   12158:     
                   12159:     
                   12160:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  12161:                ageminpar=50;
                   12162:                agemaxpar=100;
1.194     brouard  12163:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   12164:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12165: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12166: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   12167:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12168: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12169: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12170:     }else{
                   12171:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   12172:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  12173:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  12174:                }
1.201     brouard  12175:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  12176:                     stepm, weightopt,\
                   12177:                     model,imx,p,matcov,agemortsup);
                   12178:     
1.302     brouard  12179:     free_vector(lsurv,agegomp,AGESUP);
                   12180:     free_vector(lpop,agegomp,AGESUP);
                   12181:     free_vector(tpop,agegomp,AGESUP);
1.220     brouard  12182:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  12183:     free_ivector(dcwave,firstobs,lastobs);
                   12184:     free_vector(agecens,firstobs,lastobs);
                   12185:     free_vector(ageexmed,firstobs,lastobs);
                   12186:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  12187: #ifdef GSL
1.136     brouard  12188: #endif
1.186     brouard  12189:   } /* Endof if mle==-3 mortality only */
1.205     brouard  12190:   /* Standard  */
                   12191:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   12192:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12193:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  12194:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  12195:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12196:     for (k=1; k<=npar;k++)
                   12197:       printf(" %d %8.5f",k,p[k]);
                   12198:     printf("\n");
1.205     brouard  12199:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   12200:       /* mlikeli uses func not funcone */
1.247     brouard  12201:       /* for(i=1;i<nlstate;i++){ */
                   12202:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   12203:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   12204:       /* } */
1.205     brouard  12205:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   12206:     }
                   12207:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   12208:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12209:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   12210:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12211:     }
                   12212:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  12213:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12214:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12215:     for (k=1; k<=npar;k++)
                   12216:       printf(" %d %8.5f",k,p[k]);
                   12217:     printf("\n");
                   12218:     
                   12219:     /*--------- results files --------------*/
1.283     brouard  12220:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  12221:     
                   12222:     
                   12223:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12224:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12225:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12226:     for(i=1,jk=1; i <=nlstate; i++){
                   12227:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  12228:        if (k != i) {
                   12229:          printf("%d%d ",i,k);
                   12230:          fprintf(ficlog,"%d%d ",i,k);
                   12231:          fprintf(ficres,"%1d%1d ",i,k);
                   12232:          for(j=1; j <=ncovmodel; j++){
                   12233:            printf("%12.7f ",p[jk]);
                   12234:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12235:            fprintf(ficres,"%12.7f ",p[jk]);
                   12236:            jk++; 
                   12237:          }
                   12238:          printf("\n");
                   12239:          fprintf(ficlog,"\n");
                   12240:          fprintf(ficres,"\n");
                   12241:        }
1.126     brouard  12242:       }
                   12243:     }
1.203     brouard  12244:     if(mle != 0){
                   12245:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12246:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12247:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12248:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12249:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12250:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12251:        for(k=1; k <=(nlstate+ndeath); k++){
                   12252:          if (k != i) {
                   12253:            printf("%d%d ",i,k);
                   12254:            fprintf(ficlog,"%d%d ",i,k);
                   12255:            for(j=1; j <=ncovmodel; j++){
                   12256:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12257:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12258:              jk++; 
                   12259:            }
                   12260:            printf("\n");
                   12261:            fprintf(ficlog,"\n");
                   12262:          }
                   12263:        }
1.193     brouard  12264:       }
1.203     brouard  12265:     } /* end of hesscov and Wald tests */
1.225     brouard  12266:     
1.203     brouard  12267:     /*  */
1.126     brouard  12268:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12269:     printf("# Scales (for hessian or gradient estimation)\n");
                   12270:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12271:     for(i=1,jk=1; i <=nlstate; i++){
                   12272:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12273:        if (j!=i) {
                   12274:          fprintf(ficres,"%1d%1d",i,j);
                   12275:          printf("%1d%1d",i,j);
                   12276:          fprintf(ficlog,"%1d%1d",i,j);
                   12277:          for(k=1; k<=ncovmodel;k++){
                   12278:            printf(" %.5e",delti[jk]);
                   12279:            fprintf(ficlog," %.5e",delti[jk]);
                   12280:            fprintf(ficres," %.5e",delti[jk]);
                   12281:            jk++;
                   12282:          }
                   12283:          printf("\n");
                   12284:          fprintf(ficlog,"\n");
                   12285:          fprintf(ficres,"\n");
                   12286:        }
1.126     brouard  12287:       }
                   12288:     }
                   12289:     
                   12290:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12291:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12292:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12293:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12294:     /* # 121 Var(a12)\n\ */
                   12295:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12296:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12297:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12298:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12299:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12300:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12301:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12302:     
                   12303:     
                   12304:     /* Just to have a covariance matrix which will be more understandable
                   12305:        even is we still don't want to manage dictionary of variables
                   12306:     */
                   12307:     for(itimes=1;itimes<=2;itimes++){
                   12308:       jj=0;
                   12309:       for(i=1; i <=nlstate; i++){
1.225     brouard  12310:        for(j=1; j <=nlstate+ndeath; j++){
                   12311:          if(j==i) continue;
                   12312:          for(k=1; k<=ncovmodel;k++){
                   12313:            jj++;
                   12314:            ca[0]= k+'a'-1;ca[1]='\0';
                   12315:            if(itimes==1){
                   12316:              if(mle>=1)
                   12317:                printf("#%1d%1d%d",i,j,k);
                   12318:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12319:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12320:            }else{
                   12321:              if(mle>=1)
                   12322:                printf("%1d%1d%d",i,j,k);
                   12323:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12324:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12325:            }
                   12326:            ll=0;
                   12327:            for(li=1;li <=nlstate; li++){
                   12328:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12329:                if(lj==li) continue;
                   12330:                for(lk=1;lk<=ncovmodel;lk++){
                   12331:                  ll++;
                   12332:                  if(ll<=jj){
                   12333:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12334:                    if(ll<jj){
                   12335:                      if(itimes==1){
                   12336:                        if(mle>=1)
                   12337:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12338:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12339:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12340:                      }else{
                   12341:                        if(mle>=1)
                   12342:                          printf(" %.5e",matcov[jj][ll]); 
                   12343:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12344:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12345:                      }
                   12346:                    }else{
                   12347:                      if(itimes==1){
                   12348:                        if(mle>=1)
                   12349:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12350:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12351:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12352:                      }else{
                   12353:                        if(mle>=1)
                   12354:                          printf(" %.7e",matcov[jj][ll]); 
                   12355:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12356:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12357:                      }
                   12358:                    }
                   12359:                  }
                   12360:                } /* end lk */
                   12361:              } /* end lj */
                   12362:            } /* end li */
                   12363:            if(mle>=1)
                   12364:              printf("\n");
                   12365:            fprintf(ficlog,"\n");
                   12366:            fprintf(ficres,"\n");
                   12367:            numlinepar++;
                   12368:          } /* end k*/
                   12369:        } /*end j */
1.126     brouard  12370:       } /* end i */
                   12371:     } /* end itimes */
                   12372:     
                   12373:     fflush(ficlog);
                   12374:     fflush(ficres);
1.225     brouard  12375:     while(fgets(line, MAXLINE, ficpar)) {
                   12376:       /* If line starts with a # it is a comment */
                   12377:       if (line[0] == '#') {
                   12378:        numlinepar++;
                   12379:        fputs(line,stdout);
                   12380:        fputs(line,ficparo);
                   12381:        fputs(line,ficlog);
1.299     brouard  12382:        fputs(line,ficres);
1.225     brouard  12383:        continue;
                   12384:       }else
                   12385:        break;
                   12386:     }
                   12387:     
1.209     brouard  12388:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12389:     /*   ungetc(c,ficpar); */
                   12390:     /*   fgets(line, MAXLINE, ficpar); */
                   12391:     /*   fputs(line,stdout); */
                   12392:     /*   fputs(line,ficparo); */
                   12393:     /* } */
                   12394:     /* ungetc(c,ficpar); */
1.126     brouard  12395:     
                   12396:     estepm=0;
1.209     brouard  12397:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12398:       
                   12399:       if (num_filled != 6) {
                   12400:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12401:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12402:        goto end;
                   12403:       }
                   12404:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12405:     }
                   12406:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12407:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12408:     
1.209     brouard  12409:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12410:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12411:     if (fage <= 2) {
                   12412:       bage = ageminpar;
                   12413:       fage = agemaxpar;
                   12414:     }
                   12415:     
                   12416:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12417:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12418:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12419:                
1.186     brouard  12420:     /* Other stuffs, more or less useful */    
1.254     brouard  12421:     while(fgets(line, MAXLINE, ficpar)) {
                   12422:       /* If line starts with a # it is a comment */
                   12423:       if (line[0] == '#') {
                   12424:        numlinepar++;
                   12425:        fputs(line,stdout);
                   12426:        fputs(line,ficparo);
                   12427:        fputs(line,ficlog);
1.299     brouard  12428:        fputs(line,ficres);
1.254     brouard  12429:        continue;
                   12430:       }else
                   12431:        break;
                   12432:     }
                   12433: 
                   12434:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12435:       
                   12436:       if (num_filled != 7) {
                   12437:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12438:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12439:        goto end;
                   12440:       }
                   12441:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12442:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12443:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12444:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12445:     }
1.254     brouard  12446: 
                   12447:     while(fgets(line, MAXLINE, ficpar)) {
                   12448:       /* If line starts with a # it is a comment */
                   12449:       if (line[0] == '#') {
                   12450:        numlinepar++;
                   12451:        fputs(line,stdout);
                   12452:        fputs(line,ficparo);
                   12453:        fputs(line,ficlog);
1.299     brouard  12454:        fputs(line,ficres);
1.254     brouard  12455:        continue;
                   12456:       }else
                   12457:        break;
1.126     brouard  12458:     }
                   12459:     
                   12460:     
                   12461:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12462:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12463:     
1.254     brouard  12464:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12465:       if (num_filled != 1) {
                   12466:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12467:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12468:        goto end;
                   12469:       }
                   12470:       printf("pop_based=%d\n",popbased);
                   12471:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12472:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12473:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12474:     }
                   12475:      
1.258     brouard  12476:     /* Results */
1.307     brouard  12477:     endishere=0;
1.258     brouard  12478:     nresult=0;
1.308     brouard  12479:     parameterline=0;
1.258     brouard  12480:     do{
                   12481:       if(!fgets(line, MAXLINE, ficpar)){
                   12482:        endishere=1;
1.308     brouard  12483:        parameterline=15;
1.258     brouard  12484:       }else if (line[0] == '#') {
                   12485:        /* If line starts with a # it is a comment */
1.254     brouard  12486:        numlinepar++;
                   12487:        fputs(line,stdout);
                   12488:        fputs(line,ficparo);
                   12489:        fputs(line,ficlog);
1.299     brouard  12490:        fputs(line,ficres);
1.254     brouard  12491:        continue;
1.258     brouard  12492:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12493:        parameterline=11;
1.296     brouard  12494:       else if(sscanf(line,"prevbackcast=%[^\n]\n",modeltemp))
1.258     brouard  12495:        parameterline=12;
1.307     brouard  12496:       else if(sscanf(line,"result:%[^\n]\n",modeltemp)){
1.258     brouard  12497:        parameterline=13;
1.307     brouard  12498:       }
1.258     brouard  12499:       else{
                   12500:        parameterline=14;
1.254     brouard  12501:       }
1.308     brouard  12502:       switch (parameterline){ /* =0 only if only comments */
1.258     brouard  12503:       case 11:
1.296     brouard  12504:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12505:                  fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.258     brouard  12506:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12507:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12508:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12509:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12510:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12511:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
1.296     brouard  12512:           prvforecast = 1;
                   12513:        } 
                   12514:        else if((num_filled=sscanf(line,"prevforecast=%d yearsfproj=%lf mobil_average=%d\n",&prevfcast,&yrfproj,&mobilavproj)) !=EOF){/* && (num_filled == 3))*/
1.313   ! brouard  12515:          printf("prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
        !          12516:          fprintf(ficlog,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
        !          12517:          fprintf(ficres,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
1.296     brouard  12518:           prvforecast = 2;
                   12519:        }
                   12520:        else {
                   12521:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearsfproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12522:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12523:          goto end;
1.258     brouard  12524:        }
1.254     brouard  12525:        break;
1.258     brouard  12526:       case 12:
1.296     brouard  12527:        if((num_filled=sscanf(line,"prevbackcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&prevbcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12528:           fprintf(ficparo,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12529:          printf("prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12530:          fprintf(ficlog,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12531:          fprintf(ficres,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12532:          /* day and month of back2 are not used but only year anback2.*/
1.273     brouard  12533:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12534:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.296     brouard  12535:           prvbackcast = 1;
                   12536:        } 
                   12537:        else if((num_filled=sscanf(line,"prevbackcast=%d yearsbproj=%lf mobil_average=%d\n",&prevbcast,&yrbproj,&mobilavproj)) ==3){/* && (num_filled == 3))*/
1.313   ! brouard  12538:          printf("prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
        !          12539:          fprintf(ficlog,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
        !          12540:          fprintf(ficres,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
1.296     brouard  12541:           prvbackcast = 2;
                   12542:        }
                   12543:        else {
                   12544:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearsbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12545:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12546:          goto end;
1.258     brouard  12547:        }
1.230     brouard  12548:        break;
1.258     brouard  12549:       case 13:
1.307     brouard  12550:        num_filled=sscanf(line,"result:%[^\n]\n",resultline);
                   12551:        nresult++; /* Sum of resultlines */
                   12552:        printf("Result %d: result:%s\n",nresult, resultline);
                   12553:        if(nresult > MAXRESULTLINES){
                   12554:          printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINES,nresult,rfileres);
                   12555:          fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINES,nresult,rfileres);
                   12556:          goto end;
                   12557:        }
1.310     brouard  12558:        if(!decoderesult(resultline, nresult)){ /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.307     brouard  12559:        fprintf(ficparo,"result: %s\n",resultline);
                   12560:        fprintf(ficres,"result: %s\n",resultline);
                   12561:        fprintf(ficlog,"result: %s\n",resultline);
1.310     brouard  12562:        } else
                   12563:          goto end;
1.307     brouard  12564:        break;
                   12565:       case 14:
                   12566:        printf("Error: Unknown command '%s'\n",line);
                   12567:        fprintf(ficlog,"Error: Unknown command '%s'\n",line);
                   12568:        if(ncovmodel >=2 && nresult==0 ){
                   12569:          printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
                   12570:          fprintf(ficlog,"ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12571:        }
1.307     brouard  12572:        /* goto end; */
                   12573:        break;
1.308     brouard  12574:       case 15:
                   12575:        printf("End of resultlines.\n");
                   12576:        fprintf(ficlog,"End of resultlines.\n");
                   12577:        break;
                   12578:       default: /* parameterline =0 */
1.307     brouard  12579:        nresult=1;
                   12580:        decoderesult(".",nresult ); /* No covariate */
1.258     brouard  12581:       } /* End switch parameterline */
                   12582:     }while(endishere==0); /* End do */
1.126     brouard  12583:     
1.230     brouard  12584:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12585:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12586:     
                   12587:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12588:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12589:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12590: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12591: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12592:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12593: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12594: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12595:     }else{
1.270     brouard  12596:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
1.296     brouard  12597:       /* It seems that anprojd which is computed from the mean year at interview which is known yet because of freqsummary */
                   12598:       /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */ /* Done in freqsummary */
                   12599:       if(prvforecast==1){
                   12600:         dateprojd=(jproj1+12*mproj1+365*anproj1)/365;
                   12601:         jprojd=jproj1;
                   12602:         mprojd=mproj1;
                   12603:         anprojd=anproj1;
                   12604:         dateprojf=(jproj2+12*mproj2+365*anproj2)/365;
                   12605:         jprojf=jproj2;
                   12606:         mprojf=mproj2;
                   12607:         anprojf=anproj2;
                   12608:       } else if(prvforecast == 2){
                   12609:         dateprojd=dateintmean;
                   12610:         date2dmy(dateprojd,&jprojd, &mprojd, &anprojd);
                   12611:         dateprojf=dateintmean+yrfproj;
                   12612:         date2dmy(dateprojf,&jprojf, &mprojf, &anprojf);
                   12613:       }
                   12614:       if(prvbackcast==1){
                   12615:         datebackd=(jback1+12*mback1+365*anback1)/365;
                   12616:         jbackd=jback1;
                   12617:         mbackd=mback1;
                   12618:         anbackd=anback1;
                   12619:         datebackf=(jback2+12*mback2+365*anback2)/365;
                   12620:         jbackf=jback2;
                   12621:         mbackf=mback2;
                   12622:         anbackf=anback2;
                   12623:       } else if(prvbackcast == 2){
                   12624:         datebackd=dateintmean;
                   12625:         date2dmy(datebackd,&jbackd, &mbackd, &anbackd);
                   12626:         datebackf=dateintmean-yrbproj;
                   12627:         date2dmy(datebackf,&jbackf, &mbackf, &anbackf);
                   12628:       }
                   12629:       
                   12630:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, prevbcast, pathc,p, (int)anprojd-bage, (int)anbackd-fage);
1.220     brouard  12631:     }
                   12632:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.296     brouard  12633:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,prevbcast, estepm, \
                   12634:                 jprev1,mprev1,anprev1,dateprev1, dateprojd, datebackd,jprev2,mprev2,anprev2,dateprev2,dateprojf, datebackf);
1.220     brouard  12635:                
1.225     brouard  12636:     /*------------ free_vector  -------------*/
                   12637:     /*  chdir(path); */
1.220     brouard  12638:                
1.215     brouard  12639:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12640:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12641:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12642:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  12643:     free_lvector(num,firstobs,lastobs);
                   12644:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  12645:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12646:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12647:     fclose(ficparo);
                   12648:     fclose(ficres);
1.220     brouard  12649:                
                   12650:                
1.186     brouard  12651:     /* Other results (useful)*/
1.220     brouard  12652:                
                   12653:                
1.126     brouard  12654:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12655:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12656:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12657:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12658:     fclose(ficrespl);
                   12659: 
                   12660:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12661:     /*#include "hpijx.h"*/
                   12662:     hPijx(p, bage, fage);
1.145     brouard  12663:     fclose(ficrespij);
1.227     brouard  12664:     
1.220     brouard  12665:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12666:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12667:     k=1;
1.126     brouard  12668:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12669:     
1.269     brouard  12670:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12671:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12672:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12673:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12674:        for(k=1;k<=ncovcombmax;k++)
                   12675:          probs[i][j][k]=0.;
1.269     brouard  12676:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12677:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12678:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12679:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12680:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12681:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12682:          for(k=1;k<=ncovcombmax;k++)
                   12683:            mobaverages[i][j][k]=0.;
1.219     brouard  12684:       mobaverage=mobaverages;
                   12685:       if (mobilav!=0) {
1.235     brouard  12686:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12687:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12688:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12689:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12690:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12691:        }
1.269     brouard  12692:       } else if (mobilavproj !=0) {
1.235     brouard  12693:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12694:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12695:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12696:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12697:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12698:        }
1.269     brouard  12699:       }else{
                   12700:        printf("Internal error moving average\n");
                   12701:        fflush(stdout);
                   12702:        exit(1);
1.219     brouard  12703:       }
                   12704:     }/* end if moving average */
1.227     brouard  12705:     
1.126     brouard  12706:     /*---------- Forecasting ------------------*/
1.296     brouard  12707:     if(prevfcast==1){ 
                   12708:       /*   /\*    if(stepm ==1){*\/ */
                   12709:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12710:       /*This done previously after freqsummary.*/
                   12711:       /*   dateprojd=(jproj1+12*mproj1+365*anproj1)/365; */
                   12712:       /*   dateprojf=(jproj2+12*mproj2+365*anproj2)/365; */
                   12713:       
                   12714:       /* } else if (prvforecast==2){ */
                   12715:       /*   /\*    if(stepm ==1){*\/ */
                   12716:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12717:       /* } */
                   12718:       /*prevforecast(fileresu, dateintmean, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);*/
                   12719:       prevforecast(fileresu,dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, p, cptcoveff);
1.126     brouard  12720:     }
1.269     brouard  12721: 
1.296     brouard  12722:     /* Prevbcasting */
                   12723:     if(prevbcast==1){
1.219     brouard  12724:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12725:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12726:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12727: 
                   12728:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12729: 
                   12730:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12731: 
1.219     brouard  12732:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12733:       fclose(ficresplb);
                   12734: 
1.222     brouard  12735:       hBijx(p, bage, fage, mobaverage);
                   12736:       fclose(ficrespijb);
1.219     brouard  12737: 
1.296     brouard  12738:       /* /\* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, *\/ */
                   12739:       /* /\*                  mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); *\/ */
                   12740:       /* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, */
                   12741:       /*                      mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
                   12742:       prevbackforecast(fileresu, mobaverage, dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2,
                   12743:                       mobilavproj, bage, fage, firstpass, lastpass, p, cptcoveff);
                   12744: 
                   12745:       
1.269     brouard  12746:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12747: 
                   12748:       
1.269     brouard  12749:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12750:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12751:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12752:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.296     brouard  12753:     }    /* end  Prevbcasting */
1.268     brouard  12754:  
1.186     brouard  12755:  
                   12756:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12757: 
1.215     brouard  12758:     free_ivector(wav,1,imx);
                   12759:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12760:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12761:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12762:                
                   12763:                
1.127     brouard  12764:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12765:                
1.201     brouard  12766:     strcpy(filerese,"E_");
                   12767:     strcat(filerese,fileresu);
1.126     brouard  12768:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12769:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12770:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12771:     }
1.208     brouard  12772:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12773:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12774: 
                   12775:     pstamp(ficreseij);
1.219     brouard  12776:                
1.235     brouard  12777:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12778:     if (cptcovn < 1){i1=1;}
                   12779:     
                   12780:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12781:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12782:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12783:        continue;
1.219     brouard  12784:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12785:       printf("\n#****** ");
1.225     brouard  12786:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12787:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12788:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12789:       }
                   12790:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12791:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12792:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12793:       }
                   12794:       fprintf(ficreseij,"******\n");
1.235     brouard  12795:       printf("******\n");
1.219     brouard  12796:       
                   12797:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12798:       oldm=oldms;savm=savms;
1.235     brouard  12799:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12800:       
1.219     brouard  12801:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12802:     }
                   12803:     fclose(ficreseij);
1.208     brouard  12804:     printf("done evsij\n");fflush(stdout);
                   12805:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12806: 
1.218     brouard  12807:                
1.227     brouard  12808:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12809:                
1.201     brouard  12810:     strcpy(filerest,"T_");
                   12811:     strcat(filerest,fileresu);
1.127     brouard  12812:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12813:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12814:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12815:     }
1.208     brouard  12816:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12817:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12818:     strcpy(fileresstde,"STDE_");
                   12819:     strcat(fileresstde,fileresu);
1.126     brouard  12820:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12821:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12822:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12823:     }
1.227     brouard  12824:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12825:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12826: 
1.201     brouard  12827:     strcpy(filerescve,"CVE_");
                   12828:     strcat(filerescve,fileresu);
1.126     brouard  12829:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12830:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12831:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12832:     }
1.227     brouard  12833:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12834:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12835: 
1.201     brouard  12836:     strcpy(fileresv,"V_");
                   12837:     strcat(fileresv,fileresu);
1.126     brouard  12838:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12839:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12840:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12841:     }
1.227     brouard  12842:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12843:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12844: 
1.235     brouard  12845:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12846:     if (cptcovn < 1){i1=1;}
                   12847:     
                   12848:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12849:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12850:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12851:        continue;
1.242     brouard  12852:       printf("\n#****** Result for:");
                   12853:       fprintf(ficrest,"\n#****** Result for:");
                   12854:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12855:       for(j=1;j<=cptcoveff;j++){ 
                   12856:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12857:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12858:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12859:       }
1.235     brouard  12860:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12861:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12862:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12863:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12864:       }        
1.208     brouard  12865:       fprintf(ficrest,"******\n");
1.227     brouard  12866:       fprintf(ficlog,"******\n");
                   12867:       printf("******\n");
1.208     brouard  12868:       
                   12869:       fprintf(ficresstdeij,"\n#****** ");
                   12870:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12871:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12872:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12873:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12874:       }
1.235     brouard  12875:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12876:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12877:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12878:       }        
1.208     brouard  12879:       fprintf(ficresstdeij,"******\n");
                   12880:       fprintf(ficrescveij,"******\n");
                   12881:       
                   12882:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12883:       /* pstamp(ficresvij); */
1.225     brouard  12884:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12885:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12886:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12887:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12888:       }        
1.208     brouard  12889:       fprintf(ficresvij,"******\n");
                   12890:       
                   12891:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12892:       oldm=oldms;savm=savms;
1.235     brouard  12893:       printf(" cvevsij ");
                   12894:       fprintf(ficlog, " cvevsij ");
                   12895:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12896:       printf(" end cvevsij \n ");
                   12897:       fprintf(ficlog, " end cvevsij \n ");
                   12898:       
                   12899:       /*
                   12900:        */
                   12901:       /* goto endfree; */
                   12902:       
                   12903:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12904:       pstamp(ficrest);
                   12905:       
1.269     brouard  12906:       epj=vector(1,nlstate+1);
1.208     brouard  12907:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12908:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12909:        cptcod= 0; /* To be deleted */
                   12910:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12911:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12912:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12913:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12914:        if(vpopbased==1)
                   12915:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12916:        else
1.288     brouard  12917:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12918:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12919:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12920:        fprintf(ficrest,"\n");
                   12921:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  12922:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   12923:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12924:        for(age=bage; age <=fage ;age++){
1.235     brouard  12925:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12926:          if (vpopbased==1) {
                   12927:            if(mobilav ==0){
                   12928:              for(i=1; i<=nlstate;i++)
                   12929:                prlim[i][i]=probs[(int)age][i][k];
                   12930:            }else{ /* mobilav */ 
                   12931:              for(i=1; i<=nlstate;i++)
                   12932:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12933:            }
                   12934:          }
1.219     brouard  12935:          
1.227     brouard  12936:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12937:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12938:          /* printf(" age %4.0f ",age); */
                   12939:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12940:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12941:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12942:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12943:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12944:            }
                   12945:            epj[nlstate+1] +=epj[j];
                   12946:          }
                   12947:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12948:          
1.227     brouard  12949:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12950:            for(j=1;j <=nlstate;j++)
                   12951:              vepp += vareij[i][j][(int)age];
                   12952:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12953:          for(j=1;j <=nlstate;j++){
                   12954:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12955:          }
                   12956:          fprintf(ficrest,"\n");
                   12957:        }
1.208     brouard  12958:       } /* End vpopbased */
1.269     brouard  12959:       free_vector(epj,1,nlstate+1);
1.208     brouard  12960:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12961:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12962:       printf("done selection\n");fflush(stdout);
                   12963:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12964:       
1.235     brouard  12965:     } /* End k selection */
1.227     brouard  12966: 
                   12967:     printf("done State-specific expectancies\n");fflush(stdout);
                   12968:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12969: 
1.288     brouard  12970:     /* variance-covariance of forward period prevalence*/
1.269     brouard  12971:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12972: 
1.227     brouard  12973:     
1.290     brouard  12974:     free_vector(weight,firstobs,lastobs);
1.227     brouard  12975:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  12976:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   12977:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   12978:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   12979:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  12980:     free_ivector(tab,1,NCOVMAX);
                   12981:     fclose(ficresstdeij);
                   12982:     fclose(ficrescveij);
                   12983:     fclose(ficresvij);
                   12984:     fclose(ficrest);
                   12985:     fclose(ficpar);
                   12986:     
                   12987:     
1.126     brouard  12988:     /*---------- End : free ----------------*/
1.219     brouard  12989:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12990:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12991:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12992:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12993:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12994:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12995:   /* endfree:*/
                   12996:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12997:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12998:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  12999:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   13000:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   13001:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   13002:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  13003:   free_matrix(matcov,1,npar,1,npar);
                   13004:   free_matrix(hess,1,npar,1,npar);
                   13005:   /*free_vector(delti,1,npar);*/
                   13006:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   13007:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  13008:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  13009:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   13010:   
                   13011:   free_ivector(ncodemax,1,NCOVMAX);
                   13012:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   13013:   free_ivector(Dummy,-1,NCOVMAX);
                   13014:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  13015:   free_ivector(DummyV,1,NCOVMAX);
                   13016:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  13017:   free_ivector(Typevar,-1,NCOVMAX);
                   13018:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  13019:   free_ivector(TvarsQ,1,NCOVMAX);
                   13020:   free_ivector(TvarsQind,1,NCOVMAX);
                   13021:   free_ivector(TvarsD,1,NCOVMAX);
                   13022:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  13023:   free_ivector(TvarFD,1,NCOVMAX);
                   13024:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  13025:   free_ivector(TvarF,1,NCOVMAX);
                   13026:   free_ivector(TvarFind,1,NCOVMAX);
                   13027:   free_ivector(TvarV,1,NCOVMAX);
                   13028:   free_ivector(TvarVind,1,NCOVMAX);
                   13029:   free_ivector(TvarA,1,NCOVMAX);
                   13030:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  13031:   free_ivector(TvarFQ,1,NCOVMAX);
                   13032:   free_ivector(TvarFQind,1,NCOVMAX);
                   13033:   free_ivector(TvarVD,1,NCOVMAX);
                   13034:   free_ivector(TvarVDind,1,NCOVMAX);
                   13035:   free_ivector(TvarVQ,1,NCOVMAX);
                   13036:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  13037:   free_ivector(Tvarsel,1,NCOVMAX);
                   13038:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  13039:   free_ivector(Tposprod,1,NCOVMAX);
                   13040:   free_ivector(Tprod,1,NCOVMAX);
                   13041:   free_ivector(Tvaraff,1,NCOVMAX);
                   13042:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   13043:   free_ivector(Tage,1,NCOVMAX);
                   13044:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  13045:   free_ivector(TmodelInvind,1,NCOVMAX);
                   13046:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  13047:   
                   13048:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   13049:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  13050:   fflush(fichtm);
                   13051:   fflush(ficgp);
                   13052:   
1.227     brouard  13053:   
1.126     brouard  13054:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  13055:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   13056:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  13057:   }else{
                   13058:     printf("End of Imach\n");
                   13059:     fprintf(ficlog,"End of Imach\n");
                   13060:   }
                   13061:   printf("See log file on %s\n",filelog);
                   13062:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  13063:   /*(void) gettimeofday(&end_time,&tzp);*/
                   13064:   rend_time = time(NULL);  
                   13065:   end_time = *localtime(&rend_time);
                   13066:   /* tml = *localtime(&end_time.tm_sec); */
                   13067:   strcpy(strtend,asctime(&end_time));
1.126     brouard  13068:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   13069:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  13070:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  13071:   
1.157     brouard  13072:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   13073:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   13074:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  13075:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   13076: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   13077:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13078:   fclose(fichtm);
                   13079:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13080:   fclose(fichtmcov);
                   13081:   fclose(ficgp);
                   13082:   fclose(ficlog);
                   13083:   /*------ End -----------*/
1.227     brouard  13084:   
1.281     brouard  13085: 
                   13086: /* Executes gnuplot */
1.227     brouard  13087:   
                   13088:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  13089: #ifdef WIN32
1.227     brouard  13090:   if (_chdir(pathcd) != 0)
                   13091:     printf("Can't move to directory %s!\n",path);
                   13092:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  13093: #else
1.227     brouard  13094:     if(chdir(pathcd) != 0)
                   13095:       printf("Can't move to directory %s!\n", path);
                   13096:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  13097: #endif 
1.126     brouard  13098:     printf("Current directory %s!\n",pathcd);
                   13099:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   13100:   sprintf(plotcmd,"gnuplot");
1.157     brouard  13101: #ifdef _WIN32
1.126     brouard  13102:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   13103: #endif
                   13104:   if(!stat(plotcmd,&info)){
1.158     brouard  13105:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13106:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  13107:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  13108:     }else
                   13109:       strcpy(pplotcmd,plotcmd);
1.157     brouard  13110: #ifdef __unix
1.126     brouard  13111:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   13112:     if(!stat(plotcmd,&info)){
1.158     brouard  13113:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13114:     }else
                   13115:       strcpy(pplotcmd,plotcmd);
                   13116: #endif
                   13117:   }else
                   13118:     strcpy(pplotcmd,plotcmd);
                   13119:   
                   13120:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  13121:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.292     brouard  13122:   strcpy(pplotcmd,plotcmd);
1.227     brouard  13123:   
1.126     brouard  13124:   if((outcmd=system(plotcmd)) != 0){
1.292     brouard  13125:     printf("Error in gnuplot, command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  13126:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  13127:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.292     brouard  13128:     if((outcmd=system(plotcmd)) != 0){
1.153     brouard  13129:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.292     brouard  13130:       strcpy(plotcmd,pplotcmd);
                   13131:     }
1.126     brouard  13132:   }
1.158     brouard  13133:   printf(" Successful, please wait...");
1.126     brouard  13134:   while (z[0] != 'q') {
                   13135:     /* chdir(path); */
1.154     brouard  13136:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  13137:     scanf("%s",z);
                   13138: /*     if (z[0] == 'c') system("./imach"); */
                   13139:     if (z[0] == 'e') {
1.158     brouard  13140: #ifdef __APPLE__
1.152     brouard  13141:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  13142: #elif __linux
                   13143:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  13144: #else
1.152     brouard  13145:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  13146: #endif
                   13147:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   13148:       system(pplotcmd);
1.126     brouard  13149:     }
                   13150:     else if (z[0] == 'g') system(plotcmd);
                   13151:     else if (z[0] == 'q') exit(0);
                   13152:   }
1.227     brouard  13153: end:
1.126     brouard  13154:   while (z[0] != 'q') {
1.195     brouard  13155:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  13156:     scanf("%s",z);
                   13157:   }
1.283     brouard  13158:   printf("End\n");
1.282     brouard  13159:   exit(0);
1.126     brouard  13160: }

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