Annotation of imach/src/imach.c, revision 1.314

1.314   ! brouard     1: /* $Id: imach.c,v 1.313 2022/04/11 15:57:42 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.314   ! brouard     4:   Revision 1.313  2022/04/11 15:57:42  brouard
        !             5:   * imach.c (Module): Error in rewriting the 'r' file with yearsfproj or yearsbproj fixed
        !             6: 
1.313     brouard     7:   Revision 1.312  2022/04/05 21:24:39  brouard
                      8:   *** empty log message ***
                      9: 
1.312     brouard    10:   Revision 1.311  2022/04/05 21:03:51  brouard
                     11:   Summary: Fixed quantitative covariates
                     12: 
                     13:          Fixed covariates (dummy or quantitative)
                     14:        with missing values have never been allowed but are ERRORS and
                     15:        program quits. Standard deviations of fixed covariates were
                     16:        wrongly computed. Mean and standard deviations of time varying
                     17:        covariates are still not computed.
                     18: 
1.311     brouard    19:   Revision 1.310  2022/03/17 08:45:53  brouard
                     20:   Summary: 99r25
                     21: 
                     22:   Improving detection of errors: result lines should be compatible with
                     23:   the model.
                     24: 
1.310     brouard    25:   Revision 1.309  2021/05/20 12:39:14  brouard
                     26:   Summary: Version 0.99r24
                     27: 
1.309     brouard    28:   Revision 1.308  2021/03/31 13:11:57  brouard
                     29:   Summary: Version 0.99r23
                     30: 
                     31: 
                     32:   * imach.c (Module): Still bugs in the result loop. Thank to Holly Benett
                     33: 
1.308     brouard    34:   Revision 1.307  2021/03/08 18:11:32  brouard
                     35:   Summary: 0.99r22 fixed bug on result:
                     36: 
1.307     brouard    37:   Revision 1.306  2021/02/20 15:44:02  brouard
                     38:   Summary: Version 0.99r21
                     39: 
                     40:   * imach.c (Module): Fix bug on quitting after result lines!
                     41:   (Module): Version 0.99r21
                     42: 
1.306     brouard    43:   Revision 1.305  2021/02/20 15:28:30  brouard
                     44:   * imach.c (Module): Fix bug on quitting after result lines!
                     45: 
1.305     brouard    46:   Revision 1.304  2021/02/12 11:34:20  brouard
                     47:   * imach.c (Module): The use of a Windows BOM (huge) file is now an error
                     48: 
1.304     brouard    49:   Revision 1.303  2021/02/11 19:50:15  brouard
                     50:   *  (Module): imach.c Someone entered 'results:' instead of 'result:'. Now it is an error which is printed.
                     51: 
1.303     brouard    52:   Revision 1.302  2020/02/22 21:00:05  brouard
                     53:   *  (Module): imach.c Update mle=-3 (for computing Life expectancy
                     54:   and life table from the data without any state)
                     55: 
1.302     brouard    56:   Revision 1.301  2019/06/04 13:51:20  brouard
                     57:   Summary: Error in 'r'parameter file backcast yearsbproj instead of yearsfproj
                     58: 
1.301     brouard    59:   Revision 1.300  2019/05/22 19:09:45  brouard
                     60:   Summary: version 0.99r19 of May 2019
                     61: 
1.300     brouard    62:   Revision 1.299  2019/05/22 18:37:08  brouard
                     63:   Summary: Cleaned 0.99r19
                     64: 
1.299     brouard    65:   Revision 1.298  2019/05/22 18:19:56  brouard
                     66:   *** empty log message ***
                     67: 
1.298     brouard    68:   Revision 1.297  2019/05/22 17:56:10  brouard
                     69:   Summary: Fix bug by moving date2dmy and nhstepm which gaefin=-1
                     70: 
1.297     brouard    71:   Revision 1.296  2019/05/20 13:03:18  brouard
                     72:   Summary: Projection syntax simplified
                     73: 
                     74: 
                     75:   We can now start projections, forward or backward, from the mean date
                     76:   of inteviews up to or down to a number of years of projection:
                     77:   prevforecast=1 yearsfproj=15.3 mobil_average=0
                     78:   or
                     79:   prevforecast=1 starting-proj-date=1/1/2007 final-proj-date=12/31/2017 mobil_average=0
                     80:   or
                     81:   prevbackcast=1 yearsbproj=12.3 mobil_average=1
                     82:   or
                     83:   prevbackcast=1 starting-back-date=1/10/1999 final-back-date=1/1/1985 mobil_average=1
                     84: 
1.296     brouard    85:   Revision 1.295  2019/05/18 09:52:50  brouard
                     86:   Summary: doxygen tex bug
                     87: 
1.295     brouard    88:   Revision 1.294  2019/05/16 14:54:33  brouard
                     89:   Summary: There was some wrong lines added
                     90: 
1.294     brouard    91:   Revision 1.293  2019/05/09 15:17:34  brouard
                     92:   *** empty log message ***
                     93: 
1.293     brouard    94:   Revision 1.292  2019/05/09 14:17:20  brouard
                     95:   Summary: Some updates
                     96: 
1.292     brouard    97:   Revision 1.291  2019/05/09 13:44:18  brouard
                     98:   Summary: Before ncovmax
                     99: 
1.291     brouard   100:   Revision 1.290  2019/05/09 13:39:37  brouard
                    101:   Summary: 0.99r18 unlimited number of individuals
                    102: 
                    103:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
                    104: 
1.290     brouard   105:   Revision 1.289  2018/12/13 09:16:26  brouard
                    106:   Summary: Bug for young ages (<-30) will be in r17
                    107: 
1.289     brouard   108:   Revision 1.288  2018/05/02 20:58:27  brouard
                    109:   Summary: Some bugs fixed
                    110: 
1.288     brouard   111:   Revision 1.287  2018/05/01 17:57:25  brouard
                    112:   Summary: Bug fixed by providing frequencies only for non missing covariates
                    113: 
1.287     brouard   114:   Revision 1.286  2018/04/27 14:27:04  brouard
                    115:   Summary: some minor bugs
                    116: 
1.286     brouard   117:   Revision 1.285  2018/04/21 21:02:16  brouard
                    118:   Summary: Some bugs fixed, valgrind tested
                    119: 
1.285     brouard   120:   Revision 1.284  2018/04/20 05:22:13  brouard
                    121:   Summary: Computing mean and stdeviation of fixed quantitative variables
                    122: 
1.284     brouard   123:   Revision 1.283  2018/04/19 14:49:16  brouard
                    124:   Summary: Some minor bugs fixed
                    125: 
1.283     brouard   126:   Revision 1.282  2018/02/27 22:50:02  brouard
                    127:   *** empty log message ***
                    128: 
1.282     brouard   129:   Revision 1.281  2018/02/27 19:25:23  brouard
                    130:   Summary: Adding second argument for quitting
                    131: 
1.281     brouard   132:   Revision 1.280  2018/02/21 07:58:13  brouard
                    133:   Summary: 0.99r15
                    134: 
                    135:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                    136: 
1.280     brouard   137:   Revision 1.279  2017/07/20 13:35:01  brouard
                    138:   Summary: temporary working
                    139: 
1.279     brouard   140:   Revision 1.278  2017/07/19 14:09:02  brouard
                    141:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                    142: 
1.278     brouard   143:   Revision 1.277  2017/07/17 08:53:49  brouard
                    144:   Summary: BOM files can be read now
                    145: 
1.277     brouard   146:   Revision 1.276  2017/06/30 15:48:31  brouard
                    147:   Summary: Graphs improvements
                    148: 
1.276     brouard   149:   Revision 1.275  2017/06/30 13:39:33  brouard
                    150:   Summary: Saito's color
                    151: 
1.275     brouard   152:   Revision 1.274  2017/06/29 09:47:08  brouard
                    153:   Summary: Version 0.99r14
                    154: 
1.274     brouard   155:   Revision 1.273  2017/06/27 11:06:02  brouard
                    156:   Summary: More documentation on projections
                    157: 
1.273     brouard   158:   Revision 1.272  2017/06/27 10:22:40  brouard
                    159:   Summary: Color of backprojection changed from 6 to 5(yellow)
                    160: 
1.272     brouard   161:   Revision 1.271  2017/06/27 10:17:50  brouard
                    162:   Summary: Some bug with rint
                    163: 
1.271     brouard   164:   Revision 1.270  2017/05/24 05:45:29  brouard
                    165:   *** empty log message ***
                    166: 
1.270     brouard   167:   Revision 1.269  2017/05/23 08:39:25  brouard
                    168:   Summary: Code into subroutine, cleanings
                    169: 
1.269     brouard   170:   Revision 1.268  2017/05/18 20:09:32  brouard
                    171:   Summary: backprojection and confidence intervals of backprevalence
                    172: 
1.268     brouard   173:   Revision 1.267  2017/05/13 10:25:05  brouard
                    174:   Summary: temporary save for backprojection
                    175: 
1.267     brouard   176:   Revision 1.266  2017/05/13 07:26:12  brouard
                    177:   Summary: Version 0.99r13 (improvements and bugs fixed)
                    178: 
1.266     brouard   179:   Revision 1.265  2017/04/26 16:22:11  brouard
                    180:   Summary: imach 0.99r13 Some bugs fixed
                    181: 
1.265     brouard   182:   Revision 1.264  2017/04/26 06:01:29  brouard
                    183:   Summary: Labels in graphs
                    184: 
1.264     brouard   185:   Revision 1.263  2017/04/24 15:23:15  brouard
                    186:   Summary: to save
                    187: 
1.263     brouard   188:   Revision 1.262  2017/04/18 16:48:12  brouard
                    189:   *** empty log message ***
                    190: 
1.262     brouard   191:   Revision 1.261  2017/04/05 10:14:09  brouard
                    192:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                    193: 
1.261     brouard   194:   Revision 1.260  2017/04/04 17:46:59  brouard
                    195:   Summary: Gnuplot indexations fixed (humm)
                    196: 
1.260     brouard   197:   Revision 1.259  2017/04/04 13:01:16  brouard
                    198:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    199: 
1.259     brouard   200:   Revision 1.258  2017/04/03 10:17:47  brouard
                    201:   Summary: Version 0.99r12
                    202: 
                    203:   Some cleanings, conformed with updated documentation.
                    204: 
1.258     brouard   205:   Revision 1.257  2017/03/29 16:53:30  brouard
                    206:   Summary: Temp
                    207: 
1.257     brouard   208:   Revision 1.256  2017/03/27 05:50:23  brouard
                    209:   Summary: Temporary
                    210: 
1.256     brouard   211:   Revision 1.255  2017/03/08 16:02:28  brouard
                    212:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    213: 
1.255     brouard   214:   Revision 1.254  2017/03/08 07:13:00  brouard
                    215:   Summary: Fixing data parameter line
                    216: 
1.254     brouard   217:   Revision 1.253  2016/12/15 11:59:41  brouard
                    218:   Summary: 0.99 in progress
                    219: 
1.253     brouard   220:   Revision 1.252  2016/09/15 21:15:37  brouard
                    221:   *** empty log message ***
                    222: 
1.252     brouard   223:   Revision 1.251  2016/09/15 15:01:13  brouard
                    224:   Summary: not working
                    225: 
1.251     brouard   226:   Revision 1.250  2016/09/08 16:07:27  brouard
                    227:   Summary: continue
                    228: 
1.250     brouard   229:   Revision 1.249  2016/09/07 17:14:18  brouard
                    230:   Summary: Starting values from frequencies
                    231: 
1.249     brouard   232:   Revision 1.248  2016/09/07 14:10:18  brouard
                    233:   *** empty log message ***
                    234: 
1.248     brouard   235:   Revision 1.247  2016/09/02 11:11:21  brouard
                    236:   *** empty log message ***
                    237: 
1.247     brouard   238:   Revision 1.246  2016/09/02 08:49:22  brouard
                    239:   *** empty log message ***
                    240: 
1.246     brouard   241:   Revision 1.245  2016/09/02 07:25:01  brouard
                    242:   *** empty log message ***
                    243: 
1.245     brouard   244:   Revision 1.244  2016/09/02 07:17:34  brouard
                    245:   *** empty log message ***
                    246: 
1.244     brouard   247:   Revision 1.243  2016/09/02 06:45:35  brouard
                    248:   *** empty log message ***
                    249: 
1.243     brouard   250:   Revision 1.242  2016/08/30 15:01:20  brouard
                    251:   Summary: Fixing a lots
                    252: 
1.242     brouard   253:   Revision 1.241  2016/08/29 17:17:25  brouard
                    254:   Summary: gnuplot problem in Back projection to fix
                    255: 
1.241     brouard   256:   Revision 1.240  2016/08/29 07:53:18  brouard
                    257:   Summary: Better
                    258: 
1.240     brouard   259:   Revision 1.239  2016/08/26 15:51:03  brouard
                    260:   Summary: Improvement in Powell output in order to copy and paste
                    261: 
                    262:   Author:
                    263: 
1.239     brouard   264:   Revision 1.238  2016/08/26 14:23:35  brouard
                    265:   Summary: Starting tests of 0.99
                    266: 
1.238     brouard   267:   Revision 1.237  2016/08/26 09:20:19  brouard
                    268:   Summary: to valgrind
                    269: 
1.237     brouard   270:   Revision 1.236  2016/08/25 10:50:18  brouard
                    271:   *** empty log message ***
                    272: 
1.236     brouard   273:   Revision 1.235  2016/08/25 06:59:23  brouard
                    274:   *** empty log message ***
                    275: 
1.235     brouard   276:   Revision 1.234  2016/08/23 16:51:20  brouard
                    277:   *** empty log message ***
                    278: 
1.234     brouard   279:   Revision 1.233  2016/08/23 07:40:50  brouard
                    280:   Summary: not working
                    281: 
1.233     brouard   282:   Revision 1.232  2016/08/22 14:20:21  brouard
                    283:   Summary: not working
                    284: 
1.232     brouard   285:   Revision 1.231  2016/08/22 07:17:15  brouard
                    286:   Summary: not working
                    287: 
1.231     brouard   288:   Revision 1.230  2016/08/22 06:55:53  brouard
                    289:   Summary: Not working
                    290: 
1.230     brouard   291:   Revision 1.229  2016/07/23 09:45:53  brouard
                    292:   Summary: Completing for func too
                    293: 
1.229     brouard   294:   Revision 1.228  2016/07/22 17:45:30  brouard
                    295:   Summary: Fixing some arrays, still debugging
                    296: 
1.227     brouard   297:   Revision 1.226  2016/07/12 18:42:34  brouard
                    298:   Summary: temp
                    299: 
1.226     brouard   300:   Revision 1.225  2016/07/12 08:40:03  brouard
                    301:   Summary: saving but not running
                    302: 
1.225     brouard   303:   Revision 1.224  2016/07/01 13:16:01  brouard
                    304:   Summary: Fixes
                    305: 
1.224     brouard   306:   Revision 1.223  2016/02/19 09:23:35  brouard
                    307:   Summary: temporary
                    308: 
1.223     brouard   309:   Revision 1.222  2016/02/17 08:14:50  brouard
                    310:   Summary: Probably last 0.98 stable version 0.98r6
                    311: 
1.222     brouard   312:   Revision 1.221  2016/02/15 23:35:36  brouard
                    313:   Summary: minor bug
                    314: 
1.220     brouard   315:   Revision 1.219  2016/02/15 00:48:12  brouard
                    316:   *** empty log message ***
                    317: 
1.219     brouard   318:   Revision 1.218  2016/02/12 11:29:23  brouard
                    319:   Summary: 0.99 Back projections
                    320: 
1.218     brouard   321:   Revision 1.217  2015/12/23 17:18:31  brouard
                    322:   Summary: Experimental backcast
                    323: 
1.217     brouard   324:   Revision 1.216  2015/12/18 17:32:11  brouard
                    325:   Summary: 0.98r4 Warning and status=-2
                    326: 
                    327:   Version 0.98r4 is now:
                    328:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    329:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    330:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    331: 
1.216     brouard   332:   Revision 1.215  2015/12/16 08:52:24  brouard
                    333:   Summary: 0.98r4 working
                    334: 
1.215     brouard   335:   Revision 1.214  2015/12/16 06:57:54  brouard
                    336:   Summary: temporary not working
                    337: 
1.214     brouard   338:   Revision 1.213  2015/12/11 18:22:17  brouard
                    339:   Summary: 0.98r4
                    340: 
1.213     brouard   341:   Revision 1.212  2015/11/21 12:47:24  brouard
                    342:   Summary: minor typo
                    343: 
1.212     brouard   344:   Revision 1.211  2015/11/21 12:41:11  brouard
                    345:   Summary: 0.98r3 with some graph of projected cross-sectional
                    346: 
                    347:   Author: Nicolas Brouard
                    348: 
1.211     brouard   349:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   350:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   351:   Summary: Adding ftolpl parameter
                    352:   Author: N Brouard
                    353: 
                    354:   We had difficulties to get smoothed confidence intervals. It was due
                    355:   to the period prevalence which wasn't computed accurately. The inner
                    356:   parameter ftolpl is now an outer parameter of the .imach parameter
                    357:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    358:   computation are long.
                    359: 
1.209     brouard   360:   Revision 1.208  2015/11/17 14:31:57  brouard
                    361:   Summary: temporary
                    362: 
1.208     brouard   363:   Revision 1.207  2015/10/27 17:36:57  brouard
                    364:   *** empty log message ***
                    365: 
1.207     brouard   366:   Revision 1.206  2015/10/24 07:14:11  brouard
                    367:   *** empty log message ***
                    368: 
1.206     brouard   369:   Revision 1.205  2015/10/23 15:50:53  brouard
                    370:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    371: 
1.205     brouard   372:   Revision 1.204  2015/10/01 16:20:26  brouard
                    373:   Summary: Some new graphs of contribution to likelihood
                    374: 
1.204     brouard   375:   Revision 1.203  2015/09/30 17:45:14  brouard
                    376:   Summary: looking at better estimation of the hessian
                    377: 
                    378:   Also a better criteria for convergence to the period prevalence And
                    379:   therefore adding the number of years needed to converge. (The
                    380:   prevalence in any alive state shold sum to one
                    381: 
1.203     brouard   382:   Revision 1.202  2015/09/22 19:45:16  brouard
                    383:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    384: 
1.202     brouard   385:   Revision 1.201  2015/09/15 17:34:58  brouard
                    386:   Summary: 0.98r0
                    387: 
                    388:   - Some new graphs like suvival functions
                    389:   - Some bugs fixed like model=1+age+V2.
                    390: 
1.201     brouard   391:   Revision 1.200  2015/09/09 16:53:55  brouard
                    392:   Summary: Big bug thanks to Flavia
                    393: 
                    394:   Even model=1+age+V2. did not work anymore
                    395: 
1.200     brouard   396:   Revision 1.199  2015/09/07 14:09:23  brouard
                    397:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    398: 
1.199     brouard   399:   Revision 1.198  2015/09/03 07:14:39  brouard
                    400:   Summary: 0.98q5 Flavia
                    401: 
1.198     brouard   402:   Revision 1.197  2015/09/01 18:24:39  brouard
                    403:   *** empty log message ***
                    404: 
1.197     brouard   405:   Revision 1.196  2015/08/18 23:17:52  brouard
                    406:   Summary: 0.98q5
                    407: 
1.196     brouard   408:   Revision 1.195  2015/08/18 16:28:39  brouard
                    409:   Summary: Adding a hack for testing purpose
                    410: 
                    411:   After reading the title, ftol and model lines, if the comment line has
                    412:   a q, starting with #q, the answer at the end of the run is quit. It
                    413:   permits to run test files in batch with ctest. The former workaround was
                    414:   $ echo q | imach foo.imach
                    415: 
1.195     brouard   416:   Revision 1.194  2015/08/18 13:32:00  brouard
                    417:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    418: 
1.194     brouard   419:   Revision 1.193  2015/08/04 07:17:42  brouard
                    420:   Summary: 0.98q4
                    421: 
1.193     brouard   422:   Revision 1.192  2015/07/16 16:49:02  brouard
                    423:   Summary: Fixing some outputs
                    424: 
1.192     brouard   425:   Revision 1.191  2015/07/14 10:00:33  brouard
                    426:   Summary: Some fixes
                    427: 
1.191     brouard   428:   Revision 1.190  2015/05/05 08:51:13  brouard
                    429:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    430: 
                    431:   Fix 1+age+.
                    432: 
1.190     brouard   433:   Revision 1.189  2015/04/30 14:45:16  brouard
                    434:   Summary: 0.98q2
                    435: 
1.189     brouard   436:   Revision 1.188  2015/04/30 08:27:53  brouard
                    437:   *** empty log message ***
                    438: 
1.188     brouard   439:   Revision 1.187  2015/04/29 09:11:15  brouard
                    440:   *** empty log message ***
                    441: 
1.187     brouard   442:   Revision 1.186  2015/04/23 12:01:52  brouard
                    443:   Summary: V1*age is working now, version 0.98q1
                    444: 
                    445:   Some codes had been disabled in order to simplify and Vn*age was
                    446:   working in the optimization phase, ie, giving correct MLE parameters,
                    447:   but, as usual, outputs were not correct and program core dumped.
                    448: 
1.186     brouard   449:   Revision 1.185  2015/03/11 13:26:42  brouard
                    450:   Summary: Inclusion of compile and links command line for Intel Compiler
                    451: 
1.185     brouard   452:   Revision 1.184  2015/03/11 11:52:39  brouard
                    453:   Summary: Back from Windows 8. Intel Compiler
                    454: 
1.184     brouard   455:   Revision 1.183  2015/03/10 20:34:32  brouard
                    456:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    457: 
                    458:   We use directest instead of original Powell test; probably no
                    459:   incidence on the results, but better justifications;
                    460:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    461:   wrong results.
                    462: 
1.183     brouard   463:   Revision 1.182  2015/02/12 08:19:57  brouard
                    464:   Summary: Trying to keep directest which seems simpler and more general
                    465:   Author: Nicolas Brouard
                    466: 
1.182     brouard   467:   Revision 1.181  2015/02/11 23:22:24  brouard
                    468:   Summary: Comments on Powell added
                    469: 
                    470:   Author:
                    471: 
1.181     brouard   472:   Revision 1.180  2015/02/11 17:33:45  brouard
                    473:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    474: 
1.180     brouard   475:   Revision 1.179  2015/01/04 09:57:06  brouard
                    476:   Summary: back to OS/X
                    477: 
1.179     brouard   478:   Revision 1.178  2015/01/04 09:35:48  brouard
                    479:   *** empty log message ***
                    480: 
1.178     brouard   481:   Revision 1.177  2015/01/03 18:40:56  brouard
                    482:   Summary: Still testing ilc32 on OSX
                    483: 
1.177     brouard   484:   Revision 1.176  2015/01/03 16:45:04  brouard
                    485:   *** empty log message ***
                    486: 
1.176     brouard   487:   Revision 1.175  2015/01/03 16:33:42  brouard
                    488:   *** empty log message ***
                    489: 
1.175     brouard   490:   Revision 1.174  2015/01/03 16:15:49  brouard
                    491:   Summary: Still in cross-compilation
                    492: 
1.174     brouard   493:   Revision 1.173  2015/01/03 12:06:26  brouard
                    494:   Summary: trying to detect cross-compilation
                    495: 
1.173     brouard   496:   Revision 1.172  2014/12/27 12:07:47  brouard
                    497:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    498: 
1.172     brouard   499:   Revision 1.171  2014/12/23 13:26:59  brouard
                    500:   Summary: Back from Visual C
                    501: 
                    502:   Still problem with utsname.h on Windows
                    503: 
1.171     brouard   504:   Revision 1.170  2014/12/23 11:17:12  brouard
                    505:   Summary: Cleaning some \%% back to %%
                    506: 
                    507:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    508: 
1.170     brouard   509:   Revision 1.169  2014/12/22 23:08:31  brouard
                    510:   Summary: 0.98p
                    511: 
                    512:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    513: 
1.169     brouard   514:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   515:   Summary: update
1.169     brouard   516: 
1.168     brouard   517:   Revision 1.167  2014/12/22 13:50:56  brouard
                    518:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    519: 
                    520:   Testing on Linux 64
                    521: 
1.167     brouard   522:   Revision 1.166  2014/12/22 11:40:47  brouard
                    523:   *** empty log message ***
                    524: 
1.166     brouard   525:   Revision 1.165  2014/12/16 11:20:36  brouard
                    526:   Summary: After compiling on Visual C
                    527: 
                    528:   * imach.c (Module): Merging 1.61 to 1.162
                    529: 
1.165     brouard   530:   Revision 1.164  2014/12/16 10:52:11  brouard
                    531:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    532: 
                    533:   * imach.c (Module): Merging 1.61 to 1.162
                    534: 
1.164     brouard   535:   Revision 1.163  2014/12/16 10:30:11  brouard
                    536:   * imach.c (Module): Merging 1.61 to 1.162
                    537: 
1.163     brouard   538:   Revision 1.162  2014/09/25 11:43:39  brouard
                    539:   Summary: temporary backup 0.99!
                    540: 
1.162     brouard   541:   Revision 1.1  2014/09/16 11:06:58  brouard
                    542:   Summary: With some code (wrong) for nlopt
                    543: 
                    544:   Author:
                    545: 
                    546:   Revision 1.161  2014/09/15 20:41:41  brouard
                    547:   Summary: Problem with macro SQR on Intel compiler
                    548: 
1.161     brouard   549:   Revision 1.160  2014/09/02 09:24:05  brouard
                    550:   *** empty log message ***
                    551: 
1.160     brouard   552:   Revision 1.159  2014/09/01 10:34:10  brouard
                    553:   Summary: WIN32
                    554:   Author: Brouard
                    555: 
1.159     brouard   556:   Revision 1.158  2014/08/27 17:11:51  brouard
                    557:   *** empty log message ***
                    558: 
1.158     brouard   559:   Revision 1.157  2014/08/27 16:26:55  brouard
                    560:   Summary: Preparing windows Visual studio version
                    561:   Author: Brouard
                    562: 
                    563:   In order to compile on Visual studio, time.h is now correct and time_t
                    564:   and tm struct should be used. difftime should be used but sometimes I
                    565:   just make the differences in raw time format (time(&now).
                    566:   Trying to suppress #ifdef LINUX
                    567:   Add xdg-open for __linux in order to open default browser.
                    568: 
1.157     brouard   569:   Revision 1.156  2014/08/25 20:10:10  brouard
                    570:   *** empty log message ***
                    571: 
1.156     brouard   572:   Revision 1.155  2014/08/25 18:32:34  brouard
                    573:   Summary: New compile, minor changes
                    574:   Author: Brouard
                    575: 
1.155     brouard   576:   Revision 1.154  2014/06/20 17:32:08  brouard
                    577:   Summary: Outputs now all graphs of convergence to period prevalence
                    578: 
1.154     brouard   579:   Revision 1.153  2014/06/20 16:45:46  brouard
                    580:   Summary: If 3 live state, convergence to period prevalence on same graph
                    581:   Author: Brouard
                    582: 
1.153     brouard   583:   Revision 1.152  2014/06/18 17:54:09  brouard
                    584:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    585: 
1.152     brouard   586:   Revision 1.151  2014/06/18 16:43:30  brouard
                    587:   *** empty log message ***
                    588: 
1.151     brouard   589:   Revision 1.150  2014/06/18 16:42:35  brouard
                    590:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    591:   Author: brouard
                    592: 
1.150     brouard   593:   Revision 1.149  2014/06/18 15:51:14  brouard
                    594:   Summary: Some fixes in parameter files errors
                    595:   Author: Nicolas Brouard
                    596: 
1.149     brouard   597:   Revision 1.148  2014/06/17 17:38:48  brouard
                    598:   Summary: Nothing new
                    599:   Author: Brouard
                    600: 
                    601:   Just a new packaging for OS/X version 0.98nS
                    602: 
1.148     brouard   603:   Revision 1.147  2014/06/16 10:33:11  brouard
                    604:   *** empty log message ***
                    605: 
1.147     brouard   606:   Revision 1.146  2014/06/16 10:20:28  brouard
                    607:   Summary: Merge
                    608:   Author: Brouard
                    609: 
                    610:   Merge, before building revised version.
                    611: 
1.146     brouard   612:   Revision 1.145  2014/06/10 21:23:15  brouard
                    613:   Summary: Debugging with valgrind
                    614:   Author: Nicolas Brouard
                    615: 
                    616:   Lot of changes in order to output the results with some covariates
                    617:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    618:   improve the code.
                    619:   No more memory valgrind error but a lot has to be done in order to
                    620:   continue the work of splitting the code into subroutines.
                    621:   Also, decodemodel has been improved. Tricode is still not
                    622:   optimal. nbcode should be improved. Documentation has been added in
                    623:   the source code.
                    624: 
1.144     brouard   625:   Revision 1.143  2014/01/26 09:45:38  brouard
                    626:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    627: 
                    628:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    629:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    630: 
1.143     brouard   631:   Revision 1.142  2014/01/26 03:57:36  brouard
                    632:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    633: 
                    634:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    635: 
1.142     brouard   636:   Revision 1.141  2014/01/26 02:42:01  brouard
                    637:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    638: 
1.141     brouard   639:   Revision 1.140  2011/09/02 10:37:54  brouard
                    640:   Summary: times.h is ok with mingw32 now.
                    641: 
1.140     brouard   642:   Revision 1.139  2010/06/14 07:50:17  brouard
                    643:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    644:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    645: 
1.139     brouard   646:   Revision 1.138  2010/04/30 18:19:40  brouard
                    647:   *** empty log message ***
                    648: 
1.138     brouard   649:   Revision 1.137  2010/04/29 18:11:38  brouard
                    650:   (Module): Checking covariates for more complex models
                    651:   than V1+V2. A lot of change to be done. Unstable.
                    652: 
1.137     brouard   653:   Revision 1.136  2010/04/26 20:30:53  brouard
                    654:   (Module): merging some libgsl code. Fixing computation
                    655:   of likelione (using inter/intrapolation if mle = 0) in order to
                    656:   get same likelihood as if mle=1.
                    657:   Some cleaning of code and comments added.
                    658: 
1.136     brouard   659:   Revision 1.135  2009/10/29 15:33:14  brouard
                    660:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    661: 
1.135     brouard   662:   Revision 1.134  2009/10/29 13:18:53  brouard
                    663:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    664: 
1.134     brouard   665:   Revision 1.133  2009/07/06 10:21:25  brouard
                    666:   just nforces
                    667: 
1.133     brouard   668:   Revision 1.132  2009/07/06 08:22:05  brouard
                    669:   Many tings
                    670: 
1.132     brouard   671:   Revision 1.131  2009/06/20 16:22:47  brouard
                    672:   Some dimensions resccaled
                    673: 
1.131     brouard   674:   Revision 1.130  2009/05/26 06:44:34  brouard
                    675:   (Module): Max Covariate is now set to 20 instead of 8. A
                    676:   lot of cleaning with variables initialized to 0. Trying to make
                    677:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    678: 
1.130     brouard   679:   Revision 1.129  2007/08/31 13:49:27  lievre
                    680:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    681: 
1.129     lievre    682:   Revision 1.128  2006/06/30 13:02:05  brouard
                    683:   (Module): Clarifications on computing e.j
                    684: 
1.128     brouard   685:   Revision 1.127  2006/04/28 18:11:50  brouard
                    686:   (Module): Yes the sum of survivors was wrong since
                    687:   imach-114 because nhstepm was no more computed in the age
                    688:   loop. Now we define nhstepma in the age loop.
                    689:   (Module): In order to speed up (in case of numerous covariates) we
                    690:   compute health expectancies (without variances) in a first step
                    691:   and then all the health expectancies with variances or standard
                    692:   deviation (needs data from the Hessian matrices) which slows the
                    693:   computation.
                    694:   In the future we should be able to stop the program is only health
                    695:   expectancies and graph are needed without standard deviations.
                    696: 
1.127     brouard   697:   Revision 1.126  2006/04/28 17:23:28  brouard
                    698:   (Module): Yes the sum of survivors was wrong since
                    699:   imach-114 because nhstepm was no more computed in the age
                    700:   loop. Now we define nhstepma in the age loop.
                    701:   Version 0.98h
                    702: 
1.126     brouard   703:   Revision 1.125  2006/04/04 15:20:31  lievre
                    704:   Errors in calculation of health expectancies. Age was not initialized.
                    705:   Forecasting file added.
                    706: 
                    707:   Revision 1.124  2006/03/22 17:13:53  lievre
                    708:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    709:   The log-likelihood is printed in the log file
                    710: 
                    711:   Revision 1.123  2006/03/20 10:52:43  brouard
                    712:   * imach.c (Module): <title> changed, corresponds to .htm file
                    713:   name. <head> headers where missing.
                    714: 
                    715:   * imach.c (Module): Weights can have a decimal point as for
                    716:   English (a comma might work with a correct LC_NUMERIC environment,
                    717:   otherwise the weight is truncated).
                    718:   Modification of warning when the covariates values are not 0 or
                    719:   1.
                    720:   Version 0.98g
                    721: 
                    722:   Revision 1.122  2006/03/20 09:45:41  brouard
                    723:   (Module): Weights can have a decimal point as for
                    724:   English (a comma might work with a correct LC_NUMERIC environment,
                    725:   otherwise the weight is truncated).
                    726:   Modification of warning when the covariates values are not 0 or
                    727:   1.
                    728:   Version 0.98g
                    729: 
                    730:   Revision 1.121  2006/03/16 17:45:01  lievre
                    731:   * imach.c (Module): Comments concerning covariates added
                    732: 
                    733:   * imach.c (Module): refinements in the computation of lli if
                    734:   status=-2 in order to have more reliable computation if stepm is
                    735:   not 1 month. Version 0.98f
                    736: 
                    737:   Revision 1.120  2006/03/16 15:10:38  lievre
                    738:   (Module): refinements in the computation of lli if
                    739:   status=-2 in order to have more reliable computation if stepm is
                    740:   not 1 month. Version 0.98f
                    741: 
                    742:   Revision 1.119  2006/03/15 17:42:26  brouard
                    743:   (Module): Bug if status = -2, the loglikelihood was
                    744:   computed as likelihood omitting the logarithm. Version O.98e
                    745: 
                    746:   Revision 1.118  2006/03/14 18:20:07  brouard
                    747:   (Module): varevsij Comments added explaining the second
                    748:   table of variances if popbased=1 .
                    749:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    750:   (Module): Function pstamp added
                    751:   (Module): Version 0.98d
                    752: 
                    753:   Revision 1.117  2006/03/14 17:16:22  brouard
                    754:   (Module): varevsij Comments added explaining the second
                    755:   table of variances if popbased=1 .
                    756:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    757:   (Module): Function pstamp added
                    758:   (Module): Version 0.98d
                    759: 
                    760:   Revision 1.116  2006/03/06 10:29:27  brouard
                    761:   (Module): Variance-covariance wrong links and
                    762:   varian-covariance of ej. is needed (Saito).
                    763: 
                    764:   Revision 1.115  2006/02/27 12:17:45  brouard
                    765:   (Module): One freematrix added in mlikeli! 0.98c
                    766: 
                    767:   Revision 1.114  2006/02/26 12:57:58  brouard
                    768:   (Module): Some improvements in processing parameter
                    769:   filename with strsep.
                    770: 
                    771:   Revision 1.113  2006/02/24 14:20:24  brouard
                    772:   (Module): Memory leaks checks with valgrind and:
                    773:   datafile was not closed, some imatrix were not freed and on matrix
                    774:   allocation too.
                    775: 
                    776:   Revision 1.112  2006/01/30 09:55:26  brouard
                    777:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    778: 
                    779:   Revision 1.111  2006/01/25 20:38:18  brouard
                    780:   (Module): Lots of cleaning and bugs added (Gompertz)
                    781:   (Module): Comments can be added in data file. Missing date values
                    782:   can be a simple dot '.'.
                    783: 
                    784:   Revision 1.110  2006/01/25 00:51:50  brouard
                    785:   (Module): Lots of cleaning and bugs added (Gompertz)
                    786: 
                    787:   Revision 1.109  2006/01/24 19:37:15  brouard
                    788:   (Module): Comments (lines starting with a #) are allowed in data.
                    789: 
                    790:   Revision 1.108  2006/01/19 18:05:42  lievre
                    791:   Gnuplot problem appeared...
                    792:   To be fixed
                    793: 
                    794:   Revision 1.107  2006/01/19 16:20:37  brouard
                    795:   Test existence of gnuplot in imach path
                    796: 
                    797:   Revision 1.106  2006/01/19 13:24:36  brouard
                    798:   Some cleaning and links added in html output
                    799: 
                    800:   Revision 1.105  2006/01/05 20:23:19  lievre
                    801:   *** empty log message ***
                    802: 
                    803:   Revision 1.104  2005/09/30 16:11:43  lievre
                    804:   (Module): sump fixed, loop imx fixed, and simplifications.
                    805:   (Module): If the status is missing at the last wave but we know
                    806:   that the person is alive, then we can code his/her status as -2
                    807:   (instead of missing=-1 in earlier versions) and his/her
                    808:   contributions to the likelihood is 1 - Prob of dying from last
                    809:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    810:   the healthy state at last known wave). Version is 0.98
                    811: 
                    812:   Revision 1.103  2005/09/30 15:54:49  lievre
                    813:   (Module): sump fixed, loop imx fixed, and simplifications.
                    814: 
                    815:   Revision 1.102  2004/09/15 17:31:30  brouard
                    816:   Add the possibility to read data file including tab characters.
                    817: 
                    818:   Revision 1.101  2004/09/15 10:38:38  brouard
                    819:   Fix on curr_time
                    820: 
                    821:   Revision 1.100  2004/07/12 18:29:06  brouard
                    822:   Add version for Mac OS X. Just define UNIX in Makefile
                    823: 
                    824:   Revision 1.99  2004/06/05 08:57:40  brouard
                    825:   *** empty log message ***
                    826: 
                    827:   Revision 1.98  2004/05/16 15:05:56  brouard
                    828:   New version 0.97 . First attempt to estimate force of mortality
                    829:   directly from the data i.e. without the need of knowing the health
                    830:   state at each age, but using a Gompertz model: log u =a + b*age .
                    831:   This is the basic analysis of mortality and should be done before any
                    832:   other analysis, in order to test if the mortality estimated from the
                    833:   cross-longitudinal survey is different from the mortality estimated
                    834:   from other sources like vital statistic data.
                    835: 
                    836:   The same imach parameter file can be used but the option for mle should be -3.
                    837: 
1.133     brouard   838:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   839:   former routines in order to include the new code within the former code.
                    840: 
                    841:   The output is very simple: only an estimate of the intercept and of
                    842:   the slope with 95% confident intervals.
                    843: 
                    844:   Current limitations:
                    845:   A) Even if you enter covariates, i.e. with the
                    846:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    847:   B) There is no computation of Life Expectancy nor Life Table.
                    848: 
                    849:   Revision 1.97  2004/02/20 13:25:42  lievre
                    850:   Version 0.96d. Population forecasting command line is (temporarily)
                    851:   suppressed.
                    852: 
                    853:   Revision 1.96  2003/07/15 15:38:55  brouard
                    854:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    855:   rewritten within the same printf. Workaround: many printfs.
                    856: 
                    857:   Revision 1.95  2003/07/08 07:54:34  brouard
                    858:   * imach.c (Repository):
                    859:   (Repository): Using imachwizard code to output a more meaningful covariance
                    860:   matrix (cov(a12,c31) instead of numbers.
                    861: 
                    862:   Revision 1.94  2003/06/27 13:00:02  brouard
                    863:   Just cleaning
                    864: 
                    865:   Revision 1.93  2003/06/25 16:33:55  brouard
                    866:   (Module): On windows (cygwin) function asctime_r doesn't
                    867:   exist so I changed back to asctime which exists.
                    868:   (Module): Version 0.96b
                    869: 
                    870:   Revision 1.92  2003/06/25 16:30:45  brouard
                    871:   (Module): On windows (cygwin) function asctime_r doesn't
                    872:   exist so I changed back to asctime which exists.
                    873: 
                    874:   Revision 1.91  2003/06/25 15:30:29  brouard
                    875:   * imach.c (Repository): Duplicated warning errors corrected.
                    876:   (Repository): Elapsed time after each iteration is now output. It
                    877:   helps to forecast when convergence will be reached. Elapsed time
                    878:   is stamped in powell.  We created a new html file for the graphs
                    879:   concerning matrix of covariance. It has extension -cov.htm.
                    880: 
                    881:   Revision 1.90  2003/06/24 12:34:15  brouard
                    882:   (Module): Some bugs corrected for windows. Also, when
                    883:   mle=-1 a template is output in file "or"mypar.txt with the design
                    884:   of the covariance matrix to be input.
                    885: 
                    886:   Revision 1.89  2003/06/24 12:30:52  brouard
                    887:   (Module): Some bugs corrected for windows. Also, when
                    888:   mle=-1 a template is output in file "or"mypar.txt with the design
                    889:   of the covariance matrix to be input.
                    890: 
                    891:   Revision 1.88  2003/06/23 17:54:56  brouard
                    892:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    893: 
                    894:   Revision 1.87  2003/06/18 12:26:01  brouard
                    895:   Version 0.96
                    896: 
                    897:   Revision 1.86  2003/06/17 20:04:08  brouard
                    898:   (Module): Change position of html and gnuplot routines and added
                    899:   routine fileappend.
                    900: 
                    901:   Revision 1.85  2003/06/17 13:12:43  brouard
                    902:   * imach.c (Repository): Check when date of death was earlier that
                    903:   current date of interview. It may happen when the death was just
                    904:   prior to the death. In this case, dh was negative and likelihood
                    905:   was wrong (infinity). We still send an "Error" but patch by
                    906:   assuming that the date of death was just one stepm after the
                    907:   interview.
                    908:   (Repository): Because some people have very long ID (first column)
                    909:   we changed int to long in num[] and we added a new lvector for
                    910:   memory allocation. But we also truncated to 8 characters (left
                    911:   truncation)
                    912:   (Repository): No more line truncation errors.
                    913: 
                    914:   Revision 1.84  2003/06/13 21:44:43  brouard
                    915:   * imach.c (Repository): Replace "freqsummary" at a correct
                    916:   place. It differs from routine "prevalence" which may be called
                    917:   many times. Probs is memory consuming and must be used with
                    918:   parcimony.
                    919:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    920: 
                    921:   Revision 1.83  2003/06/10 13:39:11  lievre
                    922:   *** empty log message ***
                    923: 
                    924:   Revision 1.82  2003/06/05 15:57:20  brouard
                    925:   Add log in  imach.c and  fullversion number is now printed.
                    926: 
                    927: */
                    928: /*
                    929:    Interpolated Markov Chain
                    930: 
                    931:   Short summary of the programme:
                    932:   
1.227     brouard   933:   This program computes Healthy Life Expectancies or State-specific
                    934:   (if states aren't health statuses) Expectancies from
                    935:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    936: 
                    937:   -1- a first survey ("cross") where individuals from different ages
                    938:   are interviewed on their health status or degree of disability (in
                    939:   the case of a health survey which is our main interest)
                    940: 
                    941:   -2- at least a second wave of interviews ("longitudinal") which
                    942:   measure each change (if any) in individual health status.  Health
                    943:   expectancies are computed from the time spent in each health state
                    944:   according to a model. More health states you consider, more time is
                    945:   necessary to reach the Maximum Likelihood of the parameters involved
                    946:   in the model.  The simplest model is the multinomial logistic model
                    947:   where pij is the probability to be observed in state j at the second
                    948:   wave conditional to be observed in state i at the first
                    949:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    950:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    951:   have a more complex model than "constant and age", you should modify
                    952:   the program where the markup *Covariates have to be included here
                    953:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   954:   convergence.
                    955: 
                    956:   The advantage of this computer programme, compared to a simple
                    957:   multinomial logistic model, is clear when the delay between waves is not
                    958:   identical for each individual. Also, if a individual missed an
                    959:   intermediate interview, the information is lost, but taken into
                    960:   account using an interpolation or extrapolation.  
                    961: 
                    962:   hPijx is the probability to be observed in state i at age x+h
                    963:   conditional to the observed state i at age x. The delay 'h' can be
                    964:   split into an exact number (nh*stepm) of unobserved intermediate
                    965:   states. This elementary transition (by month, quarter,
                    966:   semester or year) is modelled as a multinomial logistic.  The hPx
                    967:   matrix is simply the matrix product of nh*stepm elementary matrices
                    968:   and the contribution of each individual to the likelihood is simply
                    969:   hPijx.
                    970: 
                    971:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   972:   of the life expectancies. It also computes the period (stable) prevalence.
                    973: 
                    974: Back prevalence and projections:
1.227     brouard   975: 
                    976:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    977:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    978:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    979:    mobilavproj)
                    980: 
                    981:     Computes the back prevalence limit for any combination of
                    982:     covariate values k at any age between ageminpar and agemaxpar and
                    983:     returns it in **bprlim. In the loops,
                    984: 
                    985:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    986:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    987: 
                    988:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   989:    Computes for any combination of covariates k and any age between bage and fage 
                    990:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    991:                        oldm=oldms;savm=savms;
1.227     brouard   992: 
1.267     brouard   993:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   994:      Computes the transition matrix starting at age 'age' over
                    995:      'nhstepm*hstepm*stepm' months (i.e. until
                    996:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   997:      nhstepm*hstepm matrices. 
                    998: 
                    999:      Returns p3mat[i][j][h] after calling
                   1000:      p3mat[i][j][h]=matprod2(newm,
                   1001:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                   1002:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                   1003:      oldm);
1.226     brouard  1004: 
                   1005: Important routines
                   1006: 
                   1007: - func (or funcone), computes logit (pij) distinguishing
                   1008:   o fixed variables (single or product dummies or quantitative);
                   1009:   o varying variables by:
                   1010:    (1) wave (single, product dummies, quantitative), 
                   1011:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                   1012:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                   1013:        % varying dummy (not done) or quantitative (not done);
                   1014: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                   1015:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                   1016: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                   1017:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                   1018:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard  1019: 
1.226     brouard  1020: 
                   1021:   
1.133     brouard  1022:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                   1023:            Institut national d'études démographiques, Paris.
1.126     brouard  1024:   This software have been partly granted by Euro-REVES, a concerted action
                   1025:   from the European Union.
                   1026:   It is copyrighted identically to a GNU software product, ie programme and
                   1027:   software can be distributed freely for non commercial use. Latest version
                   1028:   can be accessed at http://euroreves.ined.fr/imach .
                   1029: 
                   1030:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                   1031:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                   1032:   
                   1033:   **********************************************************************/
                   1034: /*
                   1035:   main
                   1036:   read parameterfile
                   1037:   read datafile
                   1038:   concatwav
                   1039:   freqsummary
                   1040:   if (mle >= 1)
                   1041:     mlikeli
                   1042:   print results files
                   1043:   if mle==1 
                   1044:      computes hessian
                   1045:   read end of parameter file: agemin, agemax, bage, fage, estepm
                   1046:       begin-prev-date,...
                   1047:   open gnuplot file
                   1048:   open html file
1.145     brouard  1049:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                   1050:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                   1051:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                   1052:     freexexit2 possible for memory heap.
                   1053: 
                   1054:   h Pij x                         | pij_nom  ficrestpij
                   1055:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                   1056:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                   1057:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                   1058: 
                   1059:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                   1060:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                   1061:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                   1062:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                   1063:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                   1064: 
1.126     brouard  1065:   forecasting if prevfcast==1 prevforecast call prevalence()
                   1066:   health expectancies
                   1067:   Variance-covariance of DFLE
                   1068:   prevalence()
                   1069:    movingaverage()
                   1070:   varevsij() 
                   1071:   if popbased==1 varevsij(,popbased)
                   1072:   total life expectancies
                   1073:   Variance of period (stable) prevalence
                   1074:  end
                   1075: */
                   1076: 
1.187     brouard  1077: /* #define DEBUG */
                   1078: /* #define DEBUGBRENT */
1.203     brouard  1079: /* #define DEBUGLINMIN */
                   1080: /* #define DEBUGHESS */
                   1081: #define DEBUGHESSIJ
1.224     brouard  1082: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard  1083: #define POWELL /* Instead of NLOPT */
1.224     brouard  1084: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard  1085: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                   1086: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard  1087: 
                   1088: #include <math.h>
                   1089: #include <stdio.h>
                   1090: #include <stdlib.h>
                   1091: #include <string.h>
1.226     brouard  1092: #include <ctype.h>
1.159     brouard  1093: 
                   1094: #ifdef _WIN32
                   1095: #include <io.h>
1.172     brouard  1096: #include <windows.h>
                   1097: #include <tchar.h>
1.159     brouard  1098: #else
1.126     brouard  1099: #include <unistd.h>
1.159     brouard  1100: #endif
1.126     brouard  1101: 
                   1102: #include <limits.h>
                   1103: #include <sys/types.h>
1.171     brouard  1104: 
                   1105: #if defined(__GNUC__)
                   1106: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1107: #endif
                   1108: 
1.126     brouard  1109: #include <sys/stat.h>
                   1110: #include <errno.h>
1.159     brouard  1111: /* extern int errno; */
1.126     brouard  1112: 
1.157     brouard  1113: /* #ifdef LINUX */
                   1114: /* #include <time.h> */
                   1115: /* #include "timeval.h" */
                   1116: /* #else */
                   1117: /* #include <sys/time.h> */
                   1118: /* #endif */
                   1119: 
1.126     brouard  1120: #include <time.h>
                   1121: 
1.136     brouard  1122: #ifdef GSL
                   1123: #include <gsl/gsl_errno.h>
                   1124: #include <gsl/gsl_multimin.h>
                   1125: #endif
                   1126: 
1.167     brouard  1127: 
1.162     brouard  1128: #ifdef NLOPT
                   1129: #include <nlopt.h>
                   1130: typedef struct {
                   1131:   double (* function)(double [] );
                   1132: } myfunc_data ;
                   1133: #endif
                   1134: 
1.126     brouard  1135: /* #include <libintl.h> */
                   1136: /* #define _(String) gettext (String) */
                   1137: 
1.251     brouard  1138: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1139: 
                   1140: #define GNUPLOTPROGRAM "gnuplot"
                   1141: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1142: #define FILENAMELENGTH 132
                   1143: 
                   1144: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1145: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1146: 
1.144     brouard  1147: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1148: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1149: 
                   1150: #define NINTERVMAX 8
1.144     brouard  1151: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1152: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.291     brouard  1153: #define NCOVMAX 20  /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1154: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1155: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1156: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1157: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1158: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1159: /* #define AGESUP 130 */
1.288     brouard  1160: /* #define AGESUP 150 */
                   1161: #define AGESUP 200
1.268     brouard  1162: #define AGEINF 0
1.218     brouard  1163: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1164: #define AGEBASE 40
1.194     brouard  1165: #define AGEOVERFLOW 1.e20
1.164     brouard  1166: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1167: #ifdef _WIN32
                   1168: #define DIRSEPARATOR '\\'
                   1169: #define CHARSEPARATOR "\\"
                   1170: #define ODIRSEPARATOR '/'
                   1171: #else
1.126     brouard  1172: #define DIRSEPARATOR '/'
                   1173: #define CHARSEPARATOR "/"
                   1174: #define ODIRSEPARATOR '\\'
                   1175: #endif
                   1176: 
1.314   ! brouard  1177: /* $Id: imach.c,v 1.313 2022/04/11 15:57:42 brouard Exp $ */
1.126     brouard  1178: /* $State: Exp $ */
1.196     brouard  1179: #include "version.h"
                   1180: char version[]=__IMACH_VERSION__;
1.308     brouard  1181: char copyright[]="March 2021,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2020, Nihon University 2021, INED 2000-2021";
1.314   ! brouard  1182: char fullversion[]="$Revision: 1.313 $ $Date: 2022/04/11 15:57:42 $"; 
1.126     brouard  1183: char strstart[80];
                   1184: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1185: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1186: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1187: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1188: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1189: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1190: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1191: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1192: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1193: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1194: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1195: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1196: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1197: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1198: int nsd=0; /**< Total number of single dummy variables (output) */
                   1199: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1200: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1201: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1202: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1203: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1204: int cptcov=0; /* Working variable */
1.290     brouard  1205: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1206: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.302     brouard  1207: int npar=NPARMAX; /* Number of parameters (nlstate+ndeath-1)*nlstate*ncovmodel; */
1.126     brouard  1208: int nlstate=2; /* Number of live states */
                   1209: int ndeath=1; /* Number of dead states */
1.130     brouard  1210: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1211: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1212: int popbased=0;
                   1213: 
                   1214: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1215: int maxwav=0; /* Maxim number of waves */
                   1216: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1217: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1218: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1219:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1220: int mle=1, weightopt=0;
1.126     brouard  1221: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1222: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1223: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1224:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1225: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1226: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1227: 
1.130     brouard  1228: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1229: double **matprod2(); /* test */
1.126     brouard  1230: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1231: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1232: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1233: 
1.136     brouard  1234: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1235: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1236: FILE *ficlog, *ficrespow;
1.130     brouard  1237: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1238: double fretone; /* Only one call to likelihood */
1.130     brouard  1239: long ipmx=0; /* Number of contributions */
1.126     brouard  1240: double sw; /* Sum of weights */
                   1241: char filerespow[FILENAMELENGTH];
                   1242: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1243: FILE *ficresilk;
                   1244: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1245: FILE *ficresprobmorprev;
                   1246: FILE *fichtm, *fichtmcov; /* Html File */
                   1247: FILE *ficreseij;
                   1248: char filerese[FILENAMELENGTH];
                   1249: FILE *ficresstdeij;
                   1250: char fileresstde[FILENAMELENGTH];
                   1251: FILE *ficrescveij;
                   1252: char filerescve[FILENAMELENGTH];
                   1253: FILE  *ficresvij;
                   1254: char fileresv[FILENAMELENGTH];
1.269     brouard  1255: 
1.126     brouard  1256: char title[MAXLINE];
1.234     brouard  1257: char model[MAXLINE]; /**< The model line */
1.217     brouard  1258: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1259: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1260: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1261: char command[FILENAMELENGTH];
                   1262: int  outcmd=0;
                   1263: 
1.217     brouard  1264: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1265: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1266: char filelog[FILENAMELENGTH]; /* Log file */
                   1267: char filerest[FILENAMELENGTH];
                   1268: char fileregp[FILENAMELENGTH];
                   1269: char popfile[FILENAMELENGTH];
                   1270: 
                   1271: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1272: 
1.157     brouard  1273: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1274: /* struct timezone tzp; */
                   1275: /* extern int gettimeofday(); */
                   1276: struct tm tml, *gmtime(), *localtime();
                   1277: 
                   1278: extern time_t time();
                   1279: 
                   1280: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1281: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1282: struct tm tm;
                   1283: 
1.126     brouard  1284: char strcurr[80], strfor[80];
                   1285: 
                   1286: char *endptr;
                   1287: long lval;
                   1288: double dval;
                   1289: 
                   1290: #define NR_END 1
                   1291: #define FREE_ARG char*
                   1292: #define FTOL 1.0e-10
                   1293: 
                   1294: #define NRANSI 
1.240     brouard  1295: #define ITMAX 200
                   1296: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1297: 
                   1298: #define TOL 2.0e-4 
                   1299: 
                   1300: #define CGOLD 0.3819660 
                   1301: #define ZEPS 1.0e-10 
                   1302: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1303: 
                   1304: #define GOLD 1.618034 
                   1305: #define GLIMIT 100.0 
                   1306: #define TINY 1.0e-20 
                   1307: 
                   1308: static double maxarg1,maxarg2;
                   1309: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1310: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1311:   
                   1312: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1313: #define rint(a) floor(a+0.5)
1.166     brouard  1314: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1315: #define mytinydouble 1.0e-16
1.166     brouard  1316: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1317: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1318: /* static double dsqrarg; */
                   1319: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1320: static double sqrarg;
                   1321: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1322: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1323: int agegomp= AGEGOMP;
                   1324: 
                   1325: int imx; 
                   1326: int stepm=1;
                   1327: /* Stepm, step in month: minimum step interpolation*/
                   1328: 
                   1329: int estepm;
                   1330: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1331: 
                   1332: int m,nb;
                   1333: long *num;
1.197     brouard  1334: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1335: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1336:                   covariate for which somebody answered excluding 
                   1337:                   undefined. Usually 2: 0 and 1. */
                   1338: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1339:                             covariate for which somebody answered including 
                   1340:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1341: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1342: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1343: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1344: double *ageexmed,*agecens;
                   1345: double dateintmean=0;
1.296     brouard  1346:   double anprojd, mprojd, jprojd; /* For eventual projections */
                   1347:   double anprojf, mprojf, jprojf;
1.126     brouard  1348: 
1.296     brouard  1349:   double anbackd, mbackd, jbackd; /* For eventual backprojections */
                   1350:   double anbackf, mbackf, jbackf;
                   1351:   double jintmean,mintmean,aintmean;  
1.126     brouard  1352: double *weight;
                   1353: int **s; /* Status */
1.141     brouard  1354: double *agedc;
1.145     brouard  1355: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1356:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1357:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1358: double **coqvar; /* Fixed quantitative covariate nqv */
                   1359: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1360: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1361: double  idx; 
                   1362: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1363: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1364: /*k          1  2   3   4     5    6    7     8    9 */
                   1365: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1366: /* Tndvar[k]    1   2   3               4          5 */
                   1367: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1368: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1369: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1370: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1371: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1372: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1373: /* Tprod[i]=k           4               7            */
                   1374: /* Tage[i]=k                  5               8      */
                   1375: /* */
                   1376: /* Type                    */
                   1377: /* V         1  2  3  4  5 */
                   1378: /*           F  F  V  V  V */
                   1379: /*           D  Q  D  D  Q */
                   1380: /*                         */
                   1381: int *TvarsD;
                   1382: int *TvarsDind;
                   1383: int *TvarsQ;
                   1384: int *TvarsQind;
                   1385: 
1.235     brouard  1386: #define MAXRESULTLINES 10
                   1387: int nresult=0;
1.258     brouard  1388: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1389: int TKresult[MAXRESULTLINES];
1.237     brouard  1390: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1391: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1392: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1393: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1394: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1395: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1396: 
1.234     brouard  1397: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1398: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1399: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1400: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1401: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1402: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1403: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1404: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1405: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1406: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1407: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1408: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1409: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1410: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1411: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1412: 
1.230     brouard  1413: int *Tvarsel; /**< Selected covariates for output */
                   1414: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1415: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1416: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1417: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1418: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1419: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1420: int *Tage;
1.227     brouard  1421: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1422: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1423: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1424: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1425: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1426: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1427: int **Tvard;
                   1428: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1429: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1430: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1431:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1432:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1433: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1434: double *lsurv, *lpop, *tpop;
                   1435: 
1.231     brouard  1436: #define FD 1; /* Fixed dummy covariate */
                   1437: #define FQ 2; /* Fixed quantitative covariate */
                   1438: #define FP 3; /* Fixed product covariate */
                   1439: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1440: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1441: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1442: #define VD 10; /* Varying dummy covariate */
                   1443: #define VQ 11; /* Varying quantitative covariate */
                   1444: #define VP 12; /* Varying product covariate */
                   1445: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1446: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1447: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1448: #define APFD 16; /* Age product * fixed dummy covariate */
                   1449: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1450: #define APVD 18; /* Age product * varying dummy covariate */
                   1451: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1452: 
                   1453: #define FTYPE 1; /* Fixed covariate */
                   1454: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1455: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1456: 
                   1457: struct kmodel{
                   1458:        int maintype; /* main type */
                   1459:        int subtype; /* subtype */
                   1460: };
                   1461: struct kmodel modell[NCOVMAX];
                   1462: 
1.143     brouard  1463: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1464: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1465: 
                   1466: /**************** split *************************/
                   1467: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1468: {
                   1469:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1470:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1471:   */ 
                   1472:   char *ss;                            /* pointer */
1.186     brouard  1473:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1474: 
                   1475:   l1 = strlen(path );                  /* length of path */
                   1476:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1477:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1478:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1479:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1480:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1481:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1482:     /* get current working directory */
                   1483:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1484: #ifdef WIN32
                   1485:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1486: #else
                   1487:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1488: #endif
1.126     brouard  1489:       return( GLOCK_ERROR_GETCWD );
                   1490:     }
                   1491:     /* got dirc from getcwd*/
                   1492:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1493:   } else {                             /* strip directory from path */
1.126     brouard  1494:     ss++;                              /* after this, the filename */
                   1495:     l2 = strlen( ss );                 /* length of filename */
                   1496:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1497:     strcpy( name, ss );                /* save file name */
                   1498:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1499:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1500:     printf(" DIRC2 = %s \n",dirc);
                   1501:   }
                   1502:   /* We add a separator at the end of dirc if not exists */
                   1503:   l1 = strlen( dirc );                 /* length of directory */
                   1504:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1505:     dirc[l1] =  DIRSEPARATOR;
                   1506:     dirc[l1+1] = 0; 
                   1507:     printf(" DIRC3 = %s \n",dirc);
                   1508:   }
                   1509:   ss = strrchr( name, '.' );           /* find last / */
                   1510:   if (ss >0){
                   1511:     ss++;
                   1512:     strcpy(ext,ss);                    /* save extension */
                   1513:     l1= strlen( name);
                   1514:     l2= strlen(ss)+1;
                   1515:     strncpy( finame, name, l1-l2);
                   1516:     finame[l1-l2]= 0;
                   1517:   }
                   1518: 
                   1519:   return( 0 );                         /* we're done */
                   1520: }
                   1521: 
                   1522: 
                   1523: /******************************************/
                   1524: 
                   1525: void replace_back_to_slash(char *s, char*t)
                   1526: {
                   1527:   int i;
                   1528:   int lg=0;
                   1529:   i=0;
                   1530:   lg=strlen(t);
                   1531:   for(i=0; i<= lg; i++) {
                   1532:     (s[i] = t[i]);
                   1533:     if (t[i]== '\\') s[i]='/';
                   1534:   }
                   1535: }
                   1536: 
1.132     brouard  1537: char *trimbb(char *out, char *in)
1.137     brouard  1538: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1539:   char *s;
                   1540:   s=out;
                   1541:   while (*in != '\0'){
1.137     brouard  1542:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1543:       in++;
                   1544:     }
                   1545:     *out++ = *in++;
                   1546:   }
                   1547:   *out='\0';
                   1548:   return s;
                   1549: }
                   1550: 
1.187     brouard  1551: /* char *substrchaine(char *out, char *in, char *chain) */
                   1552: /* { */
                   1553: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1554: /*   char *s, *t; */
                   1555: /*   t=in;s=out; */
                   1556: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1557: /*     *out++ = *in++; */
                   1558: /*   } */
                   1559: 
                   1560: /*   /\* *in matches *chain *\/ */
                   1561: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1562: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1563: /*   } */
                   1564: /*   in--; chain--; */
                   1565: /*   while ( (*in != '\0')){ */
                   1566: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1567: /*     *out++ = *in++; */
                   1568: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1569: /*   } */
                   1570: /*   *out='\0'; */
                   1571: /*   out=s; */
                   1572: /*   return out; */
                   1573: /* } */
                   1574: char *substrchaine(char *out, char *in, char *chain)
                   1575: {
                   1576:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1577:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1578: 
                   1579:   char *strloc;
                   1580: 
                   1581:   strcpy (out, in); 
                   1582:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1583:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1584:   if(strloc != NULL){ 
                   1585:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1586:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1587:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1588:   }
                   1589:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1590:   return out;
                   1591: }
                   1592: 
                   1593: 
1.145     brouard  1594: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1595: {
1.187     brouard  1596:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1597:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.310     brouard  1598:      gives alocc="abcdef" and blocc="ghi2j".
1.145     brouard  1599:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1600:   */
1.160     brouard  1601:   char *s, *t;
1.145     brouard  1602:   t=in;s=in;
                   1603:   while ((*in != occ) && (*in != '\0')){
                   1604:     *alocc++ = *in++;
                   1605:   }
                   1606:   if( *in == occ){
                   1607:     *(alocc)='\0';
                   1608:     s=++in;
                   1609:   }
                   1610:  
                   1611:   if (s == t) {/* occ not found */
                   1612:     *(alocc-(in-s))='\0';
                   1613:     in=s;
                   1614:   }
                   1615:   while ( *in != '\0'){
                   1616:     *blocc++ = *in++;
                   1617:   }
                   1618: 
                   1619:   *blocc='\0';
                   1620:   return t;
                   1621: }
1.137     brouard  1622: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1623: {
1.187     brouard  1624:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1625:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1626:      gives blocc="abcdef2ghi" and alocc="j".
                   1627:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1628:   */
                   1629:   char *s, *t;
                   1630:   t=in;s=in;
                   1631:   while (*in != '\0'){
                   1632:     while( *in == occ){
                   1633:       *blocc++ = *in++;
                   1634:       s=in;
                   1635:     }
                   1636:     *blocc++ = *in++;
                   1637:   }
                   1638:   if (s == t) /* occ not found */
                   1639:     *(blocc-(in-s))='\0';
                   1640:   else
                   1641:     *(blocc-(in-s)-1)='\0';
                   1642:   in=s;
                   1643:   while ( *in != '\0'){
                   1644:     *alocc++ = *in++;
                   1645:   }
                   1646: 
                   1647:   *alocc='\0';
                   1648:   return s;
                   1649: }
                   1650: 
1.126     brouard  1651: int nbocc(char *s, char occ)
                   1652: {
                   1653:   int i,j=0;
                   1654:   int lg=20;
                   1655:   i=0;
                   1656:   lg=strlen(s);
                   1657:   for(i=0; i<= lg; i++) {
1.234     brouard  1658:     if  (s[i] == occ ) j++;
1.126     brouard  1659:   }
                   1660:   return j;
                   1661: }
                   1662: 
1.137     brouard  1663: /* void cutv(char *u,char *v, char*t, char occ) */
                   1664: /* { */
                   1665: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1666: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1667: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1668: /*   int i,lg,j,p=0; */
                   1669: /*   i=0; */
                   1670: /*   lg=strlen(t); */
                   1671: /*   for(j=0; j<=lg-1; j++) { */
                   1672: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1673: /*   } */
1.126     brouard  1674: 
1.137     brouard  1675: /*   for(j=0; j<p; j++) { */
                   1676: /*     (u[j] = t[j]); */
                   1677: /*   } */
                   1678: /*      u[p]='\0'; */
1.126     brouard  1679: 
1.137     brouard  1680: /*    for(j=0; j<= lg; j++) { */
                   1681: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1682: /*   } */
                   1683: /* } */
1.126     brouard  1684: 
1.160     brouard  1685: #ifdef _WIN32
                   1686: char * strsep(char **pp, const char *delim)
                   1687: {
                   1688:   char *p, *q;
                   1689:          
                   1690:   if ((p = *pp) == NULL)
                   1691:     return 0;
                   1692:   if ((q = strpbrk (p, delim)) != NULL)
                   1693:   {
                   1694:     *pp = q + 1;
                   1695:     *q = '\0';
                   1696:   }
                   1697:   else
                   1698:     *pp = 0;
                   1699:   return p;
                   1700: }
                   1701: #endif
                   1702: 
1.126     brouard  1703: /********************** nrerror ********************/
                   1704: 
                   1705: void nrerror(char error_text[])
                   1706: {
                   1707:   fprintf(stderr,"ERREUR ...\n");
                   1708:   fprintf(stderr,"%s\n",error_text);
                   1709:   exit(EXIT_FAILURE);
                   1710: }
                   1711: /*********************** vector *******************/
                   1712: double *vector(int nl, int nh)
                   1713: {
                   1714:   double *v;
                   1715:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1716:   if (!v) nrerror("allocation failure in vector");
                   1717:   return v-nl+NR_END;
                   1718: }
                   1719: 
                   1720: /************************ free vector ******************/
                   1721: void free_vector(double*v, int nl, int nh)
                   1722: {
                   1723:   free((FREE_ARG)(v+nl-NR_END));
                   1724: }
                   1725: 
                   1726: /************************ivector *******************************/
                   1727: int *ivector(long nl,long nh)
                   1728: {
                   1729:   int *v;
                   1730:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1731:   if (!v) nrerror("allocation failure in ivector");
                   1732:   return v-nl+NR_END;
                   1733: }
                   1734: 
                   1735: /******************free ivector **************************/
                   1736: void free_ivector(int *v, long nl, long nh)
                   1737: {
                   1738:   free((FREE_ARG)(v+nl-NR_END));
                   1739: }
                   1740: 
                   1741: /************************lvector *******************************/
                   1742: long *lvector(long nl,long nh)
                   1743: {
                   1744:   long *v;
                   1745:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1746:   if (!v) nrerror("allocation failure in ivector");
                   1747:   return v-nl+NR_END;
                   1748: }
                   1749: 
                   1750: /******************free lvector **************************/
                   1751: void free_lvector(long *v, long nl, long nh)
                   1752: {
                   1753:   free((FREE_ARG)(v+nl-NR_END));
                   1754: }
                   1755: 
                   1756: /******************* imatrix *******************************/
                   1757: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1758:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1759: { 
                   1760:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1761:   int **m; 
                   1762:   
                   1763:   /* allocate pointers to rows */ 
                   1764:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1765:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1766:   m += NR_END; 
                   1767:   m -= nrl; 
                   1768:   
                   1769:   
                   1770:   /* allocate rows and set pointers to them */ 
                   1771:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1772:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1773:   m[nrl] += NR_END; 
                   1774:   m[nrl] -= ncl; 
                   1775:   
                   1776:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1777:   
                   1778:   /* return pointer to array of pointers to rows */ 
                   1779:   return m; 
                   1780: } 
                   1781: 
                   1782: /****************** free_imatrix *************************/
                   1783: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1784:       int **m;
                   1785:       long nch,ncl,nrh,nrl; 
                   1786:      /* free an int matrix allocated by imatrix() */ 
                   1787: { 
                   1788:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1789:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1790: } 
                   1791: 
                   1792: /******************* matrix *******************************/
                   1793: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1794: {
                   1795:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1796:   double **m;
                   1797: 
                   1798:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1799:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1800:   m += NR_END;
                   1801:   m -= nrl;
                   1802: 
                   1803:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1804:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1805:   m[nrl] += NR_END;
                   1806:   m[nrl] -= ncl;
                   1807: 
                   1808:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1809:   return m;
1.145     brouard  1810:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1811: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1812: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1813:    */
                   1814: }
                   1815: 
                   1816: /*************************free matrix ************************/
                   1817: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1818: {
                   1819:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1820:   free((FREE_ARG)(m+nrl-NR_END));
                   1821: }
                   1822: 
                   1823: /******************* ma3x *******************************/
                   1824: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1825: {
                   1826:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1827:   double ***m;
                   1828: 
                   1829:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1830:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1831:   m += NR_END;
                   1832:   m -= nrl;
                   1833: 
                   1834:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1835:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1836:   m[nrl] += NR_END;
                   1837:   m[nrl] -= ncl;
                   1838: 
                   1839:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1840: 
                   1841:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1842:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1843:   m[nrl][ncl] += NR_END;
                   1844:   m[nrl][ncl] -= nll;
                   1845:   for (j=ncl+1; j<=nch; j++) 
                   1846:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1847:   
                   1848:   for (i=nrl+1; i<=nrh; i++) {
                   1849:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1850:     for (j=ncl+1; j<=nch; j++) 
                   1851:       m[i][j]=m[i][j-1]+nlay;
                   1852:   }
                   1853:   return m; 
                   1854:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1855:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1856:   */
                   1857: }
                   1858: 
                   1859: /*************************free ma3x ************************/
                   1860: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1861: {
                   1862:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1863:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1864:   free((FREE_ARG)(m+nrl-NR_END));
                   1865: }
                   1866: 
                   1867: /*************** function subdirf ***********/
                   1868: char *subdirf(char fileres[])
                   1869: {
                   1870:   /* Caution optionfilefiname is hidden */
                   1871:   strcpy(tmpout,optionfilefiname);
                   1872:   strcat(tmpout,"/"); /* Add to the right */
                   1873:   strcat(tmpout,fileres);
                   1874:   return tmpout;
                   1875: }
                   1876: 
                   1877: /*************** function subdirf2 ***********/
                   1878: char *subdirf2(char fileres[], char *preop)
                   1879: {
1.314   ! brouard  1880:   /* Example subdirf2(optionfilefiname,"FB_") with optionfilefiname="texte", result="texte/FB_texte"
        !          1881:  Errors in subdirf, 2, 3 while printing tmpout is
        !          1882:   rewritten within the same printf. Workaround: many printfs
1.126     brouard  1883:   /* Caution optionfilefiname is hidden */
                   1884:   strcpy(tmpout,optionfilefiname);
                   1885:   strcat(tmpout,"/");
                   1886:   strcat(tmpout,preop);
                   1887:   strcat(tmpout,fileres);
                   1888:   return tmpout;
                   1889: }
                   1890: 
                   1891: /*************** function subdirf3 ***********/
                   1892: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1893: {
                   1894:   
                   1895:   /* Caution optionfilefiname is hidden */
                   1896:   strcpy(tmpout,optionfilefiname);
                   1897:   strcat(tmpout,"/");
                   1898:   strcat(tmpout,preop);
                   1899:   strcat(tmpout,preop2);
                   1900:   strcat(tmpout,fileres);
                   1901:   return tmpout;
                   1902: }
1.213     brouard  1903:  
                   1904: /*************** function subdirfext ***********/
                   1905: char *subdirfext(char fileres[], char *preop, char *postop)
                   1906: {
                   1907:   
                   1908:   strcpy(tmpout,preop);
                   1909:   strcat(tmpout,fileres);
                   1910:   strcat(tmpout,postop);
                   1911:   return tmpout;
                   1912: }
1.126     brouard  1913: 
1.213     brouard  1914: /*************** function subdirfext3 ***********/
                   1915: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1916: {
                   1917:   
                   1918:   /* Caution optionfilefiname is hidden */
                   1919:   strcpy(tmpout,optionfilefiname);
                   1920:   strcat(tmpout,"/");
                   1921:   strcat(tmpout,preop);
                   1922:   strcat(tmpout,fileres);
                   1923:   strcat(tmpout,postop);
                   1924:   return tmpout;
                   1925: }
                   1926:  
1.162     brouard  1927: char *asc_diff_time(long time_sec, char ascdiff[])
                   1928: {
                   1929:   long sec_left, days, hours, minutes;
                   1930:   days = (time_sec) / (60*60*24);
                   1931:   sec_left = (time_sec) % (60*60*24);
                   1932:   hours = (sec_left) / (60*60) ;
                   1933:   sec_left = (sec_left) %(60*60);
                   1934:   minutes = (sec_left) /60;
                   1935:   sec_left = (sec_left) % (60);
                   1936:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1937:   return ascdiff;
                   1938: }
                   1939: 
1.126     brouard  1940: /***************** f1dim *************************/
                   1941: extern int ncom; 
                   1942: extern double *pcom,*xicom;
                   1943: extern double (*nrfunc)(double []); 
                   1944:  
                   1945: double f1dim(double x) 
                   1946: { 
                   1947:   int j; 
                   1948:   double f;
                   1949:   double *xt; 
                   1950:  
                   1951:   xt=vector(1,ncom); 
                   1952:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1953:   f=(*nrfunc)(xt); 
                   1954:   free_vector(xt,1,ncom); 
                   1955:   return f; 
                   1956: } 
                   1957: 
                   1958: /*****************brent *************************/
                   1959: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1960: {
                   1961:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1962:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1963:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1964:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1965:    * returned function value. 
                   1966:   */
1.126     brouard  1967:   int iter; 
                   1968:   double a,b,d,etemp;
1.159     brouard  1969:   double fu=0,fv,fw,fx;
1.164     brouard  1970:   double ftemp=0.;
1.126     brouard  1971:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1972:   double e=0.0; 
                   1973:  
                   1974:   a=(ax < cx ? ax : cx); 
                   1975:   b=(ax > cx ? ax : cx); 
                   1976:   x=w=v=bx; 
                   1977:   fw=fv=fx=(*f)(x); 
                   1978:   for (iter=1;iter<=ITMAX;iter++) { 
                   1979:     xm=0.5*(a+b); 
                   1980:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1981:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1982:     printf(".");fflush(stdout);
                   1983:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1984: #ifdef DEBUGBRENT
1.126     brouard  1985:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1986:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1987:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1988: #endif
                   1989:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1990:       *xmin=x; 
                   1991:       return fx; 
                   1992:     } 
                   1993:     ftemp=fu;
                   1994:     if (fabs(e) > tol1) { 
                   1995:       r=(x-w)*(fx-fv); 
                   1996:       q=(x-v)*(fx-fw); 
                   1997:       p=(x-v)*q-(x-w)*r; 
                   1998:       q=2.0*(q-r); 
                   1999:       if (q > 0.0) p = -p; 
                   2000:       q=fabs(q); 
                   2001:       etemp=e; 
                   2002:       e=d; 
                   2003:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  2004:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  2005:       else { 
1.224     brouard  2006:                                d=p/q; 
                   2007:                                u=x+d; 
                   2008:                                if (u-a < tol2 || b-u < tol2) 
                   2009:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  2010:       } 
                   2011:     } else { 
                   2012:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   2013:     } 
                   2014:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   2015:     fu=(*f)(u); 
                   2016:     if (fu <= fx) { 
                   2017:       if (u >= x) a=x; else b=x; 
                   2018:       SHFT(v,w,x,u) 
1.183     brouard  2019:       SHFT(fv,fw,fx,fu) 
                   2020:     } else { 
                   2021:       if (u < x) a=u; else b=u; 
                   2022:       if (fu <= fw || w == x) { 
1.224     brouard  2023:                                v=w; 
                   2024:                                w=u; 
                   2025:                                fv=fw; 
                   2026:                                fw=fu; 
1.183     brouard  2027:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  2028:                                v=u; 
                   2029:                                fv=fu; 
1.183     brouard  2030:       } 
                   2031:     } 
1.126     brouard  2032:   } 
                   2033:   nrerror("Too many iterations in brent"); 
                   2034:   *xmin=x; 
                   2035:   return fx; 
                   2036: } 
                   2037: 
                   2038: /****************** mnbrak ***********************/
                   2039: 
                   2040: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   2041:            double (*func)(double)) 
1.183     brouard  2042: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   2043: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   2044: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   2045: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   2046:    */
1.126     brouard  2047:   double ulim,u,r,q, dum;
                   2048:   double fu; 
1.187     brouard  2049: 
                   2050:   double scale=10.;
                   2051:   int iterscale=0;
                   2052: 
                   2053:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   2054:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   2055: 
                   2056: 
                   2057:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   2058:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   2059:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   2060:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   2061:   /* } */
                   2062: 
1.126     brouard  2063:   if (*fb > *fa) { 
                   2064:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  2065:     SHFT(dum,*fb,*fa,dum) 
                   2066:   } 
1.126     brouard  2067:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   2068:   *fc=(*func)(*cx); 
1.183     brouard  2069: #ifdef DEBUG
1.224     brouard  2070:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   2071:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  2072: #endif
1.224     brouard  2073:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  2074:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  2075:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  2076:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  2077:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   2078:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   2079:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  2080:       fu=(*func)(u); 
1.163     brouard  2081: #ifdef DEBUG
                   2082:       /* f(x)=A(x-u)**2+f(u) */
                   2083:       double A, fparabu; 
                   2084:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2085:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  2086:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   2087:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  2088:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   2089:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   2090:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   2091:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  2092: #endif 
1.184     brouard  2093: #ifdef MNBRAKORIGINAL
1.183     brouard  2094: #else
1.191     brouard  2095: /*       if (fu > *fc) { */
                   2096: /* #ifdef DEBUG */
                   2097: /*       printf("mnbrak4  fu > fc \n"); */
                   2098: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   2099: /* #endif */
                   2100: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   2101: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   2102: /*     dum=u; /\* Shifting c and u *\/ */
                   2103: /*     u = *cx; */
                   2104: /*     *cx = dum; */
                   2105: /*     dum = fu; */
                   2106: /*     fu = *fc; */
                   2107: /*     *fc =dum; */
                   2108: /*       } else { /\* end *\/ */
                   2109: /* #ifdef DEBUG */
                   2110: /*       printf("mnbrak3  fu < fc \n"); */
                   2111: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2112: /* #endif */
                   2113: /*     dum=u; /\* Shifting c and u *\/ */
                   2114: /*     u = *cx; */
                   2115: /*     *cx = dum; */
                   2116: /*     dum = fu; */
                   2117: /*     fu = *fc; */
                   2118: /*     *fc =dum; */
                   2119: /*       } */
1.224     brouard  2120: #ifdef DEBUGMNBRAK
                   2121:                 double A, fparabu; 
                   2122:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2123:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2124:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2125:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2126: #endif
1.191     brouard  2127:       dum=u; /* Shifting c and u */
                   2128:       u = *cx;
                   2129:       *cx = dum;
                   2130:       dum = fu;
                   2131:       fu = *fc;
                   2132:       *fc =dum;
1.183     brouard  2133: #endif
1.162     brouard  2134:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2135: #ifdef DEBUG
1.224     brouard  2136:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2137:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2138: #endif
1.126     brouard  2139:       fu=(*func)(u); 
                   2140:       if (fu < *fc) { 
1.183     brouard  2141: #ifdef DEBUG
1.224     brouard  2142:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2143:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2144: #endif
                   2145:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2146:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2147: #ifdef DEBUG
                   2148:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2149: #endif
                   2150:       } 
1.162     brouard  2151:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2152: #ifdef DEBUG
1.224     brouard  2153:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2154:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2155: #endif
1.126     brouard  2156:       u=ulim; 
                   2157:       fu=(*func)(u); 
1.183     brouard  2158:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2159: #ifdef DEBUG
1.224     brouard  2160:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2161:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2162: #endif
1.126     brouard  2163:       u=(*cx)+GOLD*(*cx-*bx); 
                   2164:       fu=(*func)(u); 
1.224     brouard  2165: #ifdef DEBUG
                   2166:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2167:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2168: #endif
1.183     brouard  2169:     } /* end tests */
1.126     brouard  2170:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2171:     SHFT(*fa,*fb,*fc,fu) 
                   2172: #ifdef DEBUG
1.224     brouard  2173:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2174:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2175: #endif
                   2176:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2177: } 
                   2178: 
                   2179: /*************** linmin ************************/
1.162     brouard  2180: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2181: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2182: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2183: the value of func at the returned location p . This is actually all accomplished by calling the
                   2184: routines mnbrak and brent .*/
1.126     brouard  2185: int ncom; 
                   2186: double *pcom,*xicom;
                   2187: double (*nrfunc)(double []); 
                   2188:  
1.224     brouard  2189: #ifdef LINMINORIGINAL
1.126     brouard  2190: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2191: #else
                   2192: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2193: #endif
1.126     brouard  2194: { 
                   2195:   double brent(double ax, double bx, double cx, 
                   2196:               double (*f)(double), double tol, double *xmin); 
                   2197:   double f1dim(double x); 
                   2198:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2199:              double *fc, double (*func)(double)); 
                   2200:   int j; 
                   2201:   double xx,xmin,bx,ax; 
                   2202:   double fx,fb,fa;
1.187     brouard  2203: 
1.203     brouard  2204: #ifdef LINMINORIGINAL
                   2205: #else
                   2206:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2207: #endif
                   2208:   
1.126     brouard  2209:   ncom=n; 
                   2210:   pcom=vector(1,n); 
                   2211:   xicom=vector(1,n); 
                   2212:   nrfunc=func; 
                   2213:   for (j=1;j<=n;j++) { 
                   2214:     pcom[j]=p[j]; 
1.202     brouard  2215:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2216:   } 
1.187     brouard  2217: 
1.203     brouard  2218: #ifdef LINMINORIGINAL
                   2219:   xx=1.;
                   2220: #else
                   2221:   axs=0.0;
                   2222:   xxs=1.;
                   2223:   do{
                   2224:     xx= xxs;
                   2225: #endif
1.187     brouard  2226:     ax=0.;
                   2227:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2228:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2229:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2230:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2231:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2232:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2233:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2234: #ifdef LINMINORIGINAL
                   2235: #else
                   2236:     if (fx != fx){
1.224     brouard  2237:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2238:                        printf("|");
                   2239:                        fprintf(ficlog,"|");
1.203     brouard  2240: #ifdef DEBUGLINMIN
1.224     brouard  2241:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2242: #endif
                   2243:     }
1.224     brouard  2244:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2245: #endif
                   2246:   
1.191     brouard  2247: #ifdef DEBUGLINMIN
                   2248:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2249:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2250: #endif
1.224     brouard  2251: #ifdef LINMINORIGINAL
                   2252: #else
                   2253:        if(fb == fx){ /* Flat function in the direction */
                   2254:                xmin=xx;
                   2255:     *flat=1;
                   2256:        }else{
                   2257:     *flat=0;
                   2258: #endif
                   2259:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2260:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2261:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2262:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2263:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2264:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2265: #ifdef DEBUG
1.224     brouard  2266:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2267:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2268: #endif
                   2269: #ifdef LINMINORIGINAL
                   2270: #else
                   2271:                        }
1.126     brouard  2272: #endif
1.191     brouard  2273: #ifdef DEBUGLINMIN
                   2274:   printf("linmin end ");
1.202     brouard  2275:   fprintf(ficlog,"linmin end ");
1.191     brouard  2276: #endif
1.126     brouard  2277:   for (j=1;j<=n;j++) { 
1.203     brouard  2278: #ifdef LINMINORIGINAL
                   2279:     xi[j] *= xmin; 
                   2280: #else
                   2281: #ifdef DEBUGLINMIN
                   2282:     if(xxs <1.0)
                   2283:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2284: #endif
                   2285:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2286: #ifdef DEBUGLINMIN
                   2287:     if(xxs <1.0)
                   2288:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2289: #endif
                   2290: #endif
1.187     brouard  2291:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2292:   } 
1.191     brouard  2293: #ifdef DEBUGLINMIN
1.203     brouard  2294:   printf("\n");
1.191     brouard  2295:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2296:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2297:   for (j=1;j<=n;j++) { 
1.202     brouard  2298:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2299:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2300:     if(j % ncovmodel == 0){
1.191     brouard  2301:       printf("\n");
1.202     brouard  2302:       fprintf(ficlog,"\n");
                   2303:     }
1.191     brouard  2304:   }
1.203     brouard  2305: #else
1.191     brouard  2306: #endif
1.126     brouard  2307:   free_vector(xicom,1,n); 
                   2308:   free_vector(pcom,1,n); 
                   2309: } 
                   2310: 
                   2311: 
                   2312: /*************** powell ************************/
1.162     brouard  2313: /*
                   2314: Minimization of a function func of n variables. Input consists of an initial starting point
                   2315: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2316: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2317: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2318: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2319: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2320:  */
1.224     brouard  2321: #ifdef LINMINORIGINAL
                   2322: #else
                   2323:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2324:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2325: #endif
1.126     brouard  2326: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2327:            double (*func)(double [])) 
                   2328: { 
1.224     brouard  2329: #ifdef LINMINORIGINAL
                   2330:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2331:              double (*func)(double [])); 
1.224     brouard  2332: #else 
1.241     brouard  2333:  void linmin(double p[], double xi[], int n, double *fret,
                   2334:             double (*func)(double []),int *flat); 
1.224     brouard  2335: #endif
1.239     brouard  2336:  int i,ibig,j,jk,k; 
1.126     brouard  2337:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2338:   double directest;
1.126     brouard  2339:   double fp,fptt;
                   2340:   double *xits;
                   2341:   int niterf, itmp;
1.224     brouard  2342: #ifdef LINMINORIGINAL
                   2343: #else
                   2344: 
                   2345:   flatdir=ivector(1,n); 
                   2346:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2347: #endif
1.126     brouard  2348: 
                   2349:   pt=vector(1,n); 
                   2350:   ptt=vector(1,n); 
                   2351:   xit=vector(1,n); 
                   2352:   xits=vector(1,n); 
                   2353:   *fret=(*func)(p); 
                   2354:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2355:   rcurr_time = time(NULL);  
1.126     brouard  2356:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2357:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2358:     ibig=0; 
                   2359:     del=0.0; 
1.157     brouard  2360:     rlast_time=rcurr_time;
                   2361:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2362:     rcurr_time = time(NULL);  
                   2363:     curr_time = *localtime(&rcurr_time);
                   2364:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2365:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2366: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2367:     for (i=1;i<=n;i++) {
1.126     brouard  2368:       fprintf(ficrespow," %.12lf", p[i]);
                   2369:     }
1.239     brouard  2370:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2371:     printf("\n#model=  1      +     age ");
                   2372:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2373:     if(nagesqr==1){
1.241     brouard  2374:        printf("  + age*age  ");
                   2375:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2376:     }
                   2377:     for(j=1;j <=ncovmodel-2;j++){
                   2378:       if(Typevar[j]==0) {
                   2379:        printf("  +      V%d  ",Tvar[j]);
                   2380:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2381:       }else if(Typevar[j]==1) {
                   2382:        printf("  +    V%d*age ",Tvar[j]);
                   2383:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2384:       }else if(Typevar[j]==2) {
                   2385:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2386:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2387:       }
                   2388:     }
1.126     brouard  2389:     printf("\n");
1.239     brouard  2390: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2391: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2392:     fprintf(ficlog,"\n");
1.239     brouard  2393:     for(i=1,jk=1; i <=nlstate; i++){
                   2394:       for(k=1; k <=(nlstate+ndeath); k++){
                   2395:        if (k != i) {
                   2396:          printf("%d%d ",i,k);
                   2397:          fprintf(ficlog,"%d%d ",i,k);
                   2398:          for(j=1; j <=ncovmodel; j++){
                   2399:            printf("%12.7f ",p[jk]);
                   2400:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2401:            jk++; 
                   2402:          }
                   2403:          printf("\n");
                   2404:          fprintf(ficlog,"\n");
                   2405:        }
                   2406:       }
                   2407:     }
1.241     brouard  2408:     if(*iter <=3 && *iter >1){
1.157     brouard  2409:       tml = *localtime(&rcurr_time);
                   2410:       strcpy(strcurr,asctime(&tml));
                   2411:       rforecast_time=rcurr_time; 
1.126     brouard  2412:       itmp = strlen(strcurr);
                   2413:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2414:        strcurr[itmp-1]='\0';
1.162     brouard  2415:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2416:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2417:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2418:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2419:        forecast_time = *localtime(&rforecast_time);
                   2420:        strcpy(strfor,asctime(&forecast_time));
                   2421:        itmp = strlen(strfor);
                   2422:        if(strfor[itmp-1]=='\n')
                   2423:          strfor[itmp-1]='\0';
                   2424:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2425:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2426:       }
                   2427:     }
1.187     brouard  2428:     for (i=1;i<=n;i++) { /* For each direction i */
                   2429:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2430:       fptt=(*fret); 
                   2431: #ifdef DEBUG
1.203     brouard  2432:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2433:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2434: #endif
1.203     brouard  2435:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2436:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2437: #ifdef LINMINORIGINAL
1.188     brouard  2438:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2439: #else
                   2440:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2441:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2442: #endif
                   2443:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2444:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2445:                                /* because that direction will be replaced unless the gain del is small */
                   2446:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2447:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2448:                                /* with the new direction. */
                   2449:                                del=fabs(fptt-(*fret)); 
                   2450:                                ibig=i; 
1.126     brouard  2451:       } 
                   2452: #ifdef DEBUG
                   2453:       printf("%d %.12e",i,(*fret));
                   2454:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2455:       for (j=1;j<=n;j++) {
1.224     brouard  2456:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2457:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2458:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2459:       }
                   2460:       for(j=1;j<=n;j++) {
1.225     brouard  2461:                                printf(" p(%d)=%.12e",j,p[j]);
                   2462:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2463:       }
                   2464:       printf("\n");
                   2465:       fprintf(ficlog,"\n");
                   2466: #endif
1.187     brouard  2467:     } /* end loop on each direction i */
                   2468:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2469:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2470:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2471:       for(j=1;j<=n;j++) {
1.302     brouard  2472:        if(flatdir[j] >0){
                   2473:          printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2474:          fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2475:        }
                   2476:        /* printf("\n"); */
                   2477:        /* fprintf(ficlog,"\n"); */
                   2478:       }
1.243     brouard  2479:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2480:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2481:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2482:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2483:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2484:       /* decreased of more than 3.84  */
                   2485:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2486:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2487:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2488:                        
1.188     brouard  2489:       /* Starting the program with initial values given by a former maximization will simply change */
                   2490:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2491:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2492:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2493: #ifdef DEBUG
                   2494:       int k[2],l;
                   2495:       k[0]=1;
                   2496:       k[1]=-1;
                   2497:       printf("Max: %.12e",(*func)(p));
                   2498:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2499:       for (j=1;j<=n;j++) {
                   2500:        printf(" %.12e",p[j]);
                   2501:        fprintf(ficlog," %.12e",p[j]);
                   2502:       }
                   2503:       printf("\n");
                   2504:       fprintf(ficlog,"\n");
                   2505:       for(l=0;l<=1;l++) {
                   2506:        for (j=1;j<=n;j++) {
                   2507:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2508:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2509:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2510:        }
                   2511:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2512:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2513:       }
                   2514: #endif
                   2515: 
1.224     brouard  2516: #ifdef LINMINORIGINAL
                   2517: #else
                   2518:       free_ivector(flatdir,1,n); 
                   2519: #endif
1.126     brouard  2520:       free_vector(xit,1,n); 
                   2521:       free_vector(xits,1,n); 
                   2522:       free_vector(ptt,1,n); 
                   2523:       free_vector(pt,1,n); 
                   2524:       return; 
1.192     brouard  2525:     } /* enough precision */ 
1.240     brouard  2526:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2527:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2528:       ptt[j]=2.0*p[j]-pt[j]; 
                   2529:       xit[j]=p[j]-pt[j]; 
                   2530:       pt[j]=p[j]; 
                   2531:     } 
1.181     brouard  2532:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2533: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2534:                if (*iter <=4) {
1.225     brouard  2535: #else
                   2536: #endif
1.224     brouard  2537: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2538: #else
1.161     brouard  2539:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2540: #endif
1.162     brouard  2541:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2542:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2543:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2544:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2545:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2546:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2547:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2548:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2549:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2550:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2551:       /* mu² and del² are equal when f3=f1 */
                   2552:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2553:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2554:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2555:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2556: #ifdef NRCORIGINAL
                   2557:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2558: #else
                   2559:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2560:       t= t- del*SQR(fp-fptt);
1.183     brouard  2561: #endif
1.202     brouard  2562:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2563: #ifdef DEBUG
1.181     brouard  2564:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2565:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2566:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2567:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2568:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2569:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2570:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2571:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2572: #endif
1.183     brouard  2573: #ifdef POWELLORIGINAL
                   2574:       if (t < 0.0) { /* Then we use it for new direction */
                   2575: #else
1.182     brouard  2576:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2577:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2578:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2579:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2580:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2581:       } 
1.181     brouard  2582:       if (directest < 0.0) { /* Then we use it for new direction */
                   2583: #endif
1.191     brouard  2584: #ifdef DEBUGLINMIN
1.234     brouard  2585:        printf("Before linmin in direction P%d-P0\n",n);
                   2586:        for (j=1;j<=n;j++) {
                   2587:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2588:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2589:          if(j % ncovmodel == 0){
                   2590:            printf("\n");
                   2591:            fprintf(ficlog,"\n");
                   2592:          }
                   2593:        }
1.224     brouard  2594: #endif
                   2595: #ifdef LINMINORIGINAL
1.234     brouard  2596:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2597: #else
1.234     brouard  2598:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2599:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2600: #endif
1.234     brouard  2601:        
1.191     brouard  2602: #ifdef DEBUGLINMIN
1.234     brouard  2603:        for (j=1;j<=n;j++) { 
                   2604:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2605:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2606:          if(j % ncovmodel == 0){
                   2607:            printf("\n");
                   2608:            fprintf(ficlog,"\n");
                   2609:          }
                   2610:        }
1.224     brouard  2611: #endif
1.234     brouard  2612:        for (j=1;j<=n;j++) { 
                   2613:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2614:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2615:        }
1.224     brouard  2616: #ifdef LINMINORIGINAL
                   2617: #else
1.234     brouard  2618:        for (j=1, flatd=0;j<=n;j++) {
                   2619:          if(flatdir[j]>0)
                   2620:            flatd++;
                   2621:        }
                   2622:        if(flatd >0){
1.255     brouard  2623:          printf("%d flat directions: ",flatd);
                   2624:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2625:          for (j=1;j<=n;j++) { 
                   2626:            if(flatdir[j]>0){
                   2627:              printf("%d ",j);
                   2628:              fprintf(ficlog,"%d ",j);
                   2629:            }
                   2630:          }
                   2631:          printf("\n");
                   2632:          fprintf(ficlog,"\n");
                   2633:        }
1.191     brouard  2634: #endif
1.234     brouard  2635:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2636:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2637:        
1.126     brouard  2638: #ifdef DEBUG
1.234     brouard  2639:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2640:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2641:        for(j=1;j<=n;j++){
                   2642:          printf(" %lf",xit[j]);
                   2643:          fprintf(ficlog," %lf",xit[j]);
                   2644:        }
                   2645:        printf("\n");
                   2646:        fprintf(ficlog,"\n");
1.126     brouard  2647: #endif
1.192     brouard  2648:       } /* end of t or directest negative */
1.224     brouard  2649: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2650: #else
1.234     brouard  2651:       } /* end if (fptt < fp)  */
1.192     brouard  2652: #endif
1.225     brouard  2653: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2654:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2655: #else
1.224     brouard  2656: #endif
1.234     brouard  2657:                } /* loop iteration */ 
1.126     brouard  2658: } 
1.234     brouard  2659:   
1.126     brouard  2660: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2661:   
1.235     brouard  2662:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2663:   {
1.279     brouard  2664:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2665:      *   (and selected quantitative values in nres)
                   2666:      *  by left multiplying the unit
                   2667:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2668:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2669:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2670:      * or prevalence in state 1, prevalence in state 2, 0
                   2671:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2672:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2673:      * Output is prlim.
                   2674:      * Initial matrix pimij 
                   2675:      */
1.206     brouard  2676:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2677:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2678:   /*  0,                   0                  , 1} */
                   2679:   /*
                   2680:    * and after some iteration: */
                   2681:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2682:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2683:   /*  0,                   0                  , 1} */
                   2684:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2685:   /* {0.51571254859325999, 0.4842874514067399, */
                   2686:   /*  0.51326036147820708, 0.48673963852179264} */
                   2687:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2688:     
1.126     brouard  2689:   int i, ii,j,k;
1.209     brouard  2690:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2691:   /* double **matprod2(); */ /* test */
1.218     brouard  2692:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2693:   double **newm;
1.209     brouard  2694:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2695:   int ncvloop=0;
1.288     brouard  2696:   int first=0;
1.169     brouard  2697:   
1.209     brouard  2698:   min=vector(1,nlstate);
                   2699:   max=vector(1,nlstate);
                   2700:   meandiff=vector(1,nlstate);
                   2701: 
1.218     brouard  2702:        /* Starting with matrix unity */
1.126     brouard  2703:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2704:     for (j=1;j<=nlstate+ndeath;j++){
                   2705:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2706:     }
1.169     brouard  2707:   
                   2708:   cov[1]=1.;
                   2709:   
                   2710:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2711:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2712:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2713:     ncvloop++;
1.126     brouard  2714:     newm=savm;
                   2715:     /* Covariates have to be included here again */
1.138     brouard  2716:     cov[2]=agefin;
1.187     brouard  2717:     if(nagesqr==1)
                   2718:       cov[3]= agefin*agefin;;
1.234     brouard  2719:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2720:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2721:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2722:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2723:     }
                   2724:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2725:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2726:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2727:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2728:     }
1.237     brouard  2729:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2730:       if(Dummy[Tvar[Tage[k]]]){
                   2731:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2732:       } else{
1.235     brouard  2733:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2734:       }
1.235     brouard  2735:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2736:     }
1.237     brouard  2737:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2738:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2739:       if(Dummy[Tvard[k][1]==0]){
                   2740:        if(Dummy[Tvard[k][2]==0]){
                   2741:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2742:        }else{
                   2743:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2744:        }
                   2745:       }else{
                   2746:        if(Dummy[Tvard[k][2]==0]){
                   2747:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2748:        }else{
                   2749:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2750:        }
                   2751:       }
1.234     brouard  2752:     }
1.138     brouard  2753:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2754:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2755:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2756:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2757:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2758:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2759:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2760:     
1.126     brouard  2761:     savm=oldm;
                   2762:     oldm=newm;
1.209     brouard  2763: 
                   2764:     for(j=1; j<=nlstate; j++){
                   2765:       max[j]=0.;
                   2766:       min[j]=1.;
                   2767:     }
                   2768:     for(i=1;i<=nlstate;i++){
                   2769:       sumnew=0;
                   2770:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2771:       for(j=1; j<=nlstate; j++){ 
                   2772:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2773:        max[j]=FMAX(max[j],prlim[i][j]);
                   2774:        min[j]=FMIN(min[j],prlim[i][j]);
                   2775:       }
                   2776:     }
                   2777: 
1.126     brouard  2778:     maxmax=0.;
1.209     brouard  2779:     for(j=1; j<=nlstate; j++){
                   2780:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2781:       maxmax=FMAX(maxmax,meandiff[j]);
                   2782:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2783:     } /* j loop */
1.203     brouard  2784:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2785:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2786:     if(maxmax < ftolpl){
1.209     brouard  2787:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2788:       free_vector(min,1,nlstate);
                   2789:       free_vector(max,1,nlstate);
                   2790:       free_vector(meandiff,1,nlstate);
1.126     brouard  2791:       return prlim;
                   2792:     }
1.288     brouard  2793:   } /* agefin loop */
1.208     brouard  2794:     /* After some age loop it doesn't converge */
1.288     brouard  2795:   if(!first){
                   2796:     first=1;
                   2797:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2798:   }
                   2799:   fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2800: 
1.209     brouard  2801:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2802:   free_vector(min,1,nlstate);
                   2803:   free_vector(max,1,nlstate);
                   2804:   free_vector(meandiff,1,nlstate);
1.208     brouard  2805:   
1.169     brouard  2806:   return prlim; /* should not reach here */
1.126     brouard  2807: }
                   2808: 
1.217     brouard  2809: 
                   2810:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2811: 
1.218     brouard  2812:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2813:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2814:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2815: {
1.264     brouard  2816:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2817:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2818:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2819:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2820:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2821:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2822:   /* Initial matrix pimij */
                   2823:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2824:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2825:   /*  0,                   0                  , 1} */
                   2826:   /*
                   2827:    * and after some iteration: */
                   2828:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2829:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2830:   /*  0,                   0                  , 1} */
                   2831:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2832:   /* {0.51571254859325999, 0.4842874514067399, */
                   2833:   /*  0.51326036147820708, 0.48673963852179264} */
                   2834:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2835: 
                   2836:   int i, ii,j,k;
1.247     brouard  2837:   int first=0;
1.217     brouard  2838:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2839:   /* double **matprod2(); */ /* test */
                   2840:   double **out, cov[NCOVMAX+1], **bmij();
                   2841:   double **newm;
1.218     brouard  2842:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2843:   double        **oldm, **savm;  /* for use */
                   2844: 
1.217     brouard  2845:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2846:   int ncvloop=0;
                   2847:   
                   2848:   min=vector(1,nlstate);
                   2849:   max=vector(1,nlstate);
                   2850:   meandiff=vector(1,nlstate);
                   2851: 
1.266     brouard  2852:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2853:   oldm=oldms; savm=savms;
                   2854:   
                   2855:   /* Starting with matrix unity */
                   2856:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2857:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2858:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2859:     }
                   2860:   
                   2861:   cov[1]=1.;
                   2862:   
                   2863:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2864:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2865:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2866:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2867:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2868:     ncvloop++;
1.218     brouard  2869:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2870:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2871:     /* Covariates have to be included here again */
                   2872:     cov[2]=agefin;
                   2873:     if(nagesqr==1)
                   2874:       cov[3]= agefin*agefin;;
1.242     brouard  2875:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2876:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2877:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2878:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2879:     }
                   2880:     /* for (k=1; k<=cptcovn;k++) { */
                   2881:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2882:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2883:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2884:     /* } */
                   2885:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2886:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2887:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2888:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2889:     }
                   2890:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2891:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2892:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2893:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2894:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2895:       if(Dummy[Tvar[Tage[k]]]){
                   2896:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2897:       } else{
                   2898:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2899:       }
                   2900:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2901:     }
                   2902:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2903:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2904:       if(Dummy[Tvard[k][1]==0]){
                   2905:        if(Dummy[Tvard[k][2]==0]){
                   2906:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2907:        }else{
                   2908:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2909:        }
                   2910:       }else{
                   2911:        if(Dummy[Tvard[k][2]==0]){
                   2912:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2913:        }else{
                   2914:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2915:        }
                   2916:       }
1.217     brouard  2917:     }
                   2918:     
                   2919:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2920:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2921:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2922:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2923:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2924:                /* ij should be linked to the correct index of cov */
                   2925:                /* age and covariate values ij are in 'cov', but we need to pass
                   2926:                 * ij for the observed prevalence at age and status and covariate
                   2927:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2928:                 */
                   2929:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2930:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2931:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2932:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2933:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2934:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2935:     /*         printf("%d newm= ",i); */
                   2936:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2937:     /*           printf("%f ",newm[i][j]); */
                   2938:     /*         } */
                   2939:     /*         printf("oldm * "); */
                   2940:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2941:     /*           printf("%f ",oldm[i][j]); */
                   2942:     /*         } */
1.268     brouard  2943:     /*         printf(" bmmij "); */
1.266     brouard  2944:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2945:     /*           printf("%f ",pmmij[i][j]); */
                   2946:     /*         } */
                   2947:     /*         printf("\n"); */
                   2948:     /*   } */
                   2949:     /* } */
1.217     brouard  2950:     savm=oldm;
                   2951:     oldm=newm;
1.266     brouard  2952: 
1.217     brouard  2953:     for(j=1; j<=nlstate; j++){
                   2954:       max[j]=0.;
                   2955:       min[j]=1.;
                   2956:     }
                   2957:     for(j=1; j<=nlstate; j++){ 
                   2958:       for(i=1;i<=nlstate;i++){
1.234     brouard  2959:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2960:        bprlim[i][j]= newm[i][j];
                   2961:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2962:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2963:       }
                   2964:     }
1.218     brouard  2965:                
1.217     brouard  2966:     maxmax=0.;
                   2967:     for(i=1; i<=nlstate; i++){
                   2968:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2969:       maxmax=FMAX(maxmax,meandiff[i]);
                   2970:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2971:     } /* i loop */
1.217     brouard  2972:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2973:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2974:     if(maxmax < ftolpl){
1.220     brouard  2975:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2976:       free_vector(min,1,nlstate);
                   2977:       free_vector(max,1,nlstate);
                   2978:       free_vector(meandiff,1,nlstate);
                   2979:       return bprlim;
                   2980:     }
1.288     brouard  2981:   } /* agefin loop */
1.217     brouard  2982:     /* After some age loop it doesn't converge */
1.288     brouard  2983:   if(!first){
1.247     brouard  2984:     first=1;
                   2985:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2986: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2987:   }
                   2988:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2989: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2990:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2991:   free_vector(min,1,nlstate);
                   2992:   free_vector(max,1,nlstate);
                   2993:   free_vector(meandiff,1,nlstate);
                   2994:   
                   2995:   return bprlim; /* should not reach here */
                   2996: }
                   2997: 
1.126     brouard  2998: /*************** transition probabilities ***************/ 
                   2999: 
                   3000: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   3001: {
1.138     brouard  3002:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  3003:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  3004:      model to the ncovmodel covariates (including constant and age).
                   3005:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3006:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3007:      ncth covariate in the global vector x is given by the formula:
                   3008:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3009:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3010:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3011:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  3012:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  3013:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  3014:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  3015:   */
                   3016:   double s1, lnpijopii;
1.126     brouard  3017:   /*double t34;*/
1.164     brouard  3018:   int i,j, nc, ii, jj;
1.126     brouard  3019: 
1.223     brouard  3020:   for(i=1; i<= nlstate; i++){
                   3021:     for(j=1; j<i;j++){
                   3022:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3023:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3024:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3025:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3026:       }
                   3027:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3028:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3029:     }
                   3030:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3031:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3032:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3033:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3034:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3035:       }
                   3036:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3037:     }
                   3038:   }
1.218     brouard  3039:   
1.223     brouard  3040:   for(i=1; i<= nlstate; i++){
                   3041:     s1=0;
                   3042:     for(j=1; j<i; j++){
                   3043:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3044:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3045:     }
                   3046:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3047:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3048:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3049:     }
                   3050:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3051:     ps[i][i]=1./(s1+1.);
                   3052:     /* Computing other pijs */
                   3053:     for(j=1; j<i; j++)
                   3054:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3055:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3056:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3057:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3058:   } /* end i */
1.218     brouard  3059:   
1.223     brouard  3060:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3061:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3062:       ps[ii][jj]=0;
                   3063:       ps[ii][ii]=1;
                   3064:     }
                   3065:   }
1.294     brouard  3066: 
                   3067: 
1.223     brouard  3068:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3069:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3070:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3071:   /*   } */
                   3072:   /*   printf("\n "); */
                   3073:   /* } */
                   3074:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3075:   /*
                   3076:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  3077:                goto end;*/
1.266     brouard  3078:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  3079: }
                   3080: 
1.218     brouard  3081: /*************** backward transition probabilities ***************/ 
                   3082: 
                   3083:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3084: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3085:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   3086: {
1.302     brouard  3087:   /* Computes the backward probability at age agefin, cov[2], and covariate combination 'ij'. In fact cov is already filled and x too.
1.266     brouard  3088:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  3089:    */
1.218     brouard  3090:   int i, ii, j,k;
1.222     brouard  3091:   
                   3092:   double **out, **pmij();
                   3093:   double sumnew=0.;
1.218     brouard  3094:   double agefin;
1.292     brouard  3095:   double k3=0.; /* constant of the w_x diagonal matrix (in order for B to sum to 1 even for death state) */
1.222     brouard  3096:   double **dnewm, **dsavm, **doldm;
                   3097:   double **bbmij;
                   3098:   
1.218     brouard  3099:   doldm=ddoldms; /* global pointers */
1.222     brouard  3100:   dnewm=ddnewms;
                   3101:   dsavm=ddsavms;
                   3102:   
                   3103:   agefin=cov[2];
1.268     brouard  3104:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3105:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3106:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3107:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3108: 
                   3109:   /* P_x */
1.266     brouard  3110:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  3111:   /* outputs pmmij which is a stochastic matrix in row */
                   3112: 
                   3113:   /* Diag(w_x) */
1.292     brouard  3114:   /* Rescaling the cross-sectional prevalence: Problem with prevacurrent which can be zero */
1.268     brouard  3115:   sumnew=0.;
1.269     brouard  3116:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3117:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.297     brouard  3118:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]); */
1.268     brouard  3119:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3120:   }
                   3121:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3122:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3123:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3124:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3125:     }
                   3126:   }else{
                   3127:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3128:       for (j=1;j<=nlstate+ndeath;j++)
                   3129:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3130:     }
                   3131:     /* if(sumnew <0.9){ */
                   3132:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3133:     /* } */
                   3134:   }
                   3135:   k3=0.0;  /* We put the last diagonal to 0 */
                   3136:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3137:       doldm[ii][ii]= k3;
                   3138:   }
                   3139:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3140:   
1.292     brouard  3141:   /* Left product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm): diag[(w_i)*Px */
                   3142:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* was a Bug Valgrind */
1.268     brouard  3143: 
1.292     brouard  3144:   /* Diag(Sum_i w^i_x p^ij_x, should be the prevalence at age x+stepm */
1.268     brouard  3145:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3146:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3147:     sumnew=0.;
1.222     brouard  3148:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3149:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3150:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3151:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3152:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3153:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3154:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3155:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3156:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3157:        /* }else */
1.268     brouard  3158:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3159:     } /*End ii */
                   3160:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3161: 
1.292     brouard  3162:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* was a Bug Valgrind */
1.268     brouard  3163:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3164:   /* end bmij */
1.266     brouard  3165:   return ps; /*pointer is unchanged */
1.218     brouard  3166: }
1.217     brouard  3167: /*************** transition probabilities ***************/ 
                   3168: 
1.218     brouard  3169: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3170: {
                   3171:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3172:      computes the probability to be observed in state j being in state i by appying the
                   3173:      model to the ncovmodel covariates (including constant and age).
                   3174:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3175:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3176:      ncth covariate in the global vector x is given by the formula:
                   3177:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3178:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3179:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3180:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3181:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3182:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3183:   */
                   3184:   double s1, lnpijopii;
                   3185:   /*double t34;*/
                   3186:   int i,j, nc, ii, jj;
                   3187: 
1.234     brouard  3188:   for(i=1; i<= nlstate; i++){
                   3189:     for(j=1; j<i;j++){
                   3190:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3191:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3192:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3193:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3194:       }
                   3195:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3196:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3197:     }
                   3198:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3199:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3200:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3201:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3202:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3203:       }
                   3204:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3205:     }
                   3206:   }
                   3207:   
                   3208:   for(i=1; i<= nlstate; i++){
                   3209:     s1=0;
                   3210:     for(j=1; j<i; j++){
                   3211:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3212:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3213:     }
                   3214:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3215:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3216:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3217:     }
                   3218:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3219:     ps[i][i]=1./(s1+1.);
                   3220:     /* Computing other pijs */
                   3221:     for(j=1; j<i; j++)
                   3222:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3223:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3224:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3225:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3226:   } /* end i */
                   3227:   
                   3228:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3229:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3230:       ps[ii][jj]=0;
                   3231:       ps[ii][ii]=1;
                   3232:     }
                   3233:   }
1.296     brouard  3234:   /* Added for prevbcast */ /* Transposed matrix too */
1.234     brouard  3235:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3236:     s1=0.;
                   3237:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3238:       s1+=ps[ii][jj];
                   3239:     }
                   3240:     for(ii=1; ii<= nlstate; ii++){
                   3241:       ps[ii][jj]=ps[ii][jj]/s1;
                   3242:     }
                   3243:   }
                   3244:   /* Transposition */
                   3245:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3246:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3247:       s1=ps[ii][jj];
                   3248:       ps[ii][jj]=ps[jj][ii];
                   3249:       ps[jj][ii]=s1;
                   3250:     }
                   3251:   }
                   3252:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3253:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3254:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3255:   /*   } */
                   3256:   /*   printf("\n "); */
                   3257:   /* } */
                   3258:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3259:   /*
                   3260:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3261:     goto end;*/
                   3262:   return ps;
1.217     brouard  3263: }
                   3264: 
                   3265: 
1.126     brouard  3266: /**************** Product of 2 matrices ******************/
                   3267: 
1.145     brouard  3268: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3269: {
                   3270:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3271:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3272:   /* in, b, out are matrice of pointers which should have been initialized 
                   3273:      before: only the contents of out is modified. The function returns
                   3274:      a pointer to pointers identical to out */
1.145     brouard  3275:   int i, j, k;
1.126     brouard  3276:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3277:     for(k=ncolol; k<=ncoloh; k++){
                   3278:       out[i][k]=0.;
                   3279:       for(j=ncl; j<=nch; j++)
                   3280:        out[i][k] +=in[i][j]*b[j][k];
                   3281:     }
1.126     brouard  3282:   return out;
                   3283: }
                   3284: 
                   3285: 
                   3286: /************* Higher Matrix Product ***************/
                   3287: 
1.235     brouard  3288: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3289: {
1.218     brouard  3290:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3291:      'nhstepm*hstepm*stepm' months (i.e. until
                   3292:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3293:      nhstepm*hstepm matrices. 
                   3294:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3295:      (typically every 2 years instead of every month which is too big 
                   3296:      for the memory).
                   3297:      Model is determined by parameters x and covariates have to be 
                   3298:      included manually here. 
                   3299: 
                   3300:      */
                   3301: 
                   3302:   int i, j, d, h, k;
1.131     brouard  3303:   double **out, cov[NCOVMAX+1];
1.126     brouard  3304:   double **newm;
1.187     brouard  3305:   double agexact;
1.214     brouard  3306:   double agebegin, ageend;
1.126     brouard  3307: 
                   3308:   /* Hstepm could be zero and should return the unit matrix */
                   3309:   for (i=1;i<=nlstate+ndeath;i++)
                   3310:     for (j=1;j<=nlstate+ndeath;j++){
                   3311:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3312:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3313:     }
                   3314:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3315:   for(h=1; h <=nhstepm; h++){
                   3316:     for(d=1; d <=hstepm; d++){
                   3317:       newm=savm;
                   3318:       /* Covariates have to be included here again */
                   3319:       cov[1]=1.;
1.214     brouard  3320:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3321:       cov[2]=agexact;
                   3322:       if(nagesqr==1)
1.227     brouard  3323:        cov[3]= agexact*agexact;
1.235     brouard  3324:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3325:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3326:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3327:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3328:       }
                   3329:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3330:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3331:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3332:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3333:       }
                   3334:       for (k=1; k<=cptcovage;k++){
                   3335:        if(Dummy[Tvar[Tage[k]]]){
                   3336:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3337:        } else{
                   3338:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3339:        }
                   3340:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3341:       }
                   3342:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3343:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3344:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3345:       }
                   3346:       /* for (k=1; k<=cptcovn;k++)  */
                   3347:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3348:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3349:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3350:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3351:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3352:       
                   3353:       
1.126     brouard  3354:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3355:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3356:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3357:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3358:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3359:       /* if((int)age == 70){ */
                   3360:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3361:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3362:       /*         printf("%d pmmij ",i); */
                   3363:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3364:       /*           printf("%f ",pmmij[i][j]); */
                   3365:       /*         } */
                   3366:       /*         printf(" oldm "); */
                   3367:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3368:       /*           printf("%f ",oldm[i][j]); */
                   3369:       /*         } */
                   3370:       /*         printf("\n"); */
                   3371:       /*       } */
                   3372:       /* } */
1.126     brouard  3373:       savm=oldm;
                   3374:       oldm=newm;
                   3375:     }
                   3376:     for(i=1; i<=nlstate+ndeath; i++)
                   3377:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3378:        po[i][j][h]=newm[i][j];
                   3379:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3380:       }
1.128     brouard  3381:     /*printf("h=%d ",h);*/
1.126     brouard  3382:   } /* end h */
1.267     brouard  3383:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3384:   return po;
                   3385: }
                   3386: 
1.217     brouard  3387: /************* Higher Back Matrix Product ***************/
1.218     brouard  3388: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3389: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3390: {
1.266     brouard  3391:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3392:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3393:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3394:      nhstepm*hstepm matrices.
                   3395:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3396:      (typically every 2 years instead of every month which is too big
1.217     brouard  3397:      for the memory).
1.218     brouard  3398:      Model is determined by parameters x and covariates have to be
1.266     brouard  3399:      included manually here. Then we use a call to bmij(x and cov)
                   3400:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3401:   */
1.217     brouard  3402: 
                   3403:   int i, j, d, h, k;
1.266     brouard  3404:   double **out, cov[NCOVMAX+1], **bmij();
                   3405:   double **newm, ***newmm;
1.217     brouard  3406:   double agexact;
                   3407:   double agebegin, ageend;
1.222     brouard  3408:   double **oldm, **savm;
1.217     brouard  3409: 
1.266     brouard  3410:   newmm=po; /* To be saved */
                   3411:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3412:   /* Hstepm could be zero and should return the unit matrix */
                   3413:   for (i=1;i<=nlstate+ndeath;i++)
                   3414:     for (j=1;j<=nlstate+ndeath;j++){
                   3415:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3416:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3417:     }
                   3418:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3419:   for(h=1; h <=nhstepm; h++){
                   3420:     for(d=1; d <=hstepm; d++){
                   3421:       newm=savm;
                   3422:       /* Covariates have to be included here again */
                   3423:       cov[1]=1.;
1.271     brouard  3424:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3425:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3426:       cov[2]=agexact;
                   3427:       if(nagesqr==1)
1.222     brouard  3428:        cov[3]= agexact*agexact;
1.266     brouard  3429:       for (k=1; k<=cptcovn;k++){
                   3430:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3431:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3432:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3433:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3434:       }
1.267     brouard  3435:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3436:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3437:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3438:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3439:       }
                   3440:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3441:        if(Dummy[Tvar[Tage[k]]]){
                   3442:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3443:        } else{
                   3444:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3445:        }
                   3446:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3447:       }
                   3448:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3449:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3450:       }                        
1.217     brouard  3451:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3452:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3453: 
1.218     brouard  3454:       /* Careful transposed matrix */
1.266     brouard  3455:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3456:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3457:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3458:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3459:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3460:       /* if((int)age == 70){ */
                   3461:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3462:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3463:       /*         printf("%d pmmij ",i); */
                   3464:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3465:       /*           printf("%f ",pmmij[i][j]); */
                   3466:       /*         } */
                   3467:       /*         printf(" oldm "); */
                   3468:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3469:       /*           printf("%f ",oldm[i][j]); */
                   3470:       /*         } */
                   3471:       /*         printf("\n"); */
                   3472:       /*       } */
                   3473:       /* } */
                   3474:       savm=oldm;
                   3475:       oldm=newm;
                   3476:     }
                   3477:     for(i=1; i<=nlstate+ndeath; i++)
                   3478:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3479:        po[i][j][h]=newm[i][j];
1.268     brouard  3480:        /* if(h==nhstepm) */
                   3481:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3482:       }
1.268     brouard  3483:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3484:   } /* end h */
1.268     brouard  3485:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3486:   return po;
                   3487: }
                   3488: 
                   3489: 
1.162     brouard  3490: #ifdef NLOPT
                   3491:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3492:   double fret;
                   3493:   double *xt;
                   3494:   int j;
                   3495:   myfunc_data *d2 = (myfunc_data *) pd;
                   3496: /* xt = (p1-1); */
                   3497:   xt=vector(1,n); 
                   3498:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3499: 
                   3500:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3501:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3502:   printf("Function = %.12lf ",fret);
                   3503:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3504:   printf("\n");
                   3505:  free_vector(xt,1,n);
                   3506:   return fret;
                   3507: }
                   3508: #endif
1.126     brouard  3509: 
                   3510: /*************** log-likelihood *************/
                   3511: double func( double *x)
                   3512: {
1.226     brouard  3513:   int i, ii, j, k, mi, d, kk;
                   3514:   int ioffset=0;
                   3515:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3516:   double **out;
                   3517:   double lli; /* Individual log likelihood */
                   3518:   int s1, s2;
1.228     brouard  3519:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3520:   double bbh, survp;
                   3521:   long ipmx;
                   3522:   double agexact;
                   3523:   /*extern weight */
                   3524:   /* We are differentiating ll according to initial status */
                   3525:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3526:   /*for(i=1;i<imx;i++) 
                   3527:     printf(" %d\n",s[4][i]);
                   3528:   */
1.162     brouard  3529: 
1.226     brouard  3530:   ++countcallfunc;
1.162     brouard  3531: 
1.226     brouard  3532:   cov[1]=1.;
1.126     brouard  3533: 
1.226     brouard  3534:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3535:   ioffset=0;
1.226     brouard  3536:   if(mle==1){
                   3537:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3538:       /* Computes the values of the ncovmodel covariates of the model
                   3539:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3540:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3541:         to be observed in j being in i according to the model.
                   3542:       */
1.243     brouard  3543:       ioffset=2+nagesqr ;
1.233     brouard  3544:    /* Fixed */
1.234     brouard  3545:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3546:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3547:       }
1.226     brouard  3548:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3549:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3550:         has been calculated etc */
                   3551:       /* For an individual i, wav[i] gives the number of effective waves */
                   3552:       /* We compute the contribution to Likelihood of each effective transition
                   3553:         mw[mi][i] is real wave of the mi th effectve wave */
                   3554:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3555:         s2=s[mw[mi+1][i]][i];
                   3556:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3557:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3558:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3559:       */
                   3560:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3561:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3562:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3563:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3564:        }
                   3565:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3566:          for (j=1;j<=nlstate+ndeath;j++){
                   3567:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3568:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3569:          }
                   3570:        for(d=0; d<dh[mi][i]; d++){
                   3571:          newm=savm;
                   3572:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3573:          cov[2]=agexact;
                   3574:          if(nagesqr==1)
                   3575:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3576:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3577:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3578:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3579:          else
                   3580:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3581:          }
                   3582:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3583:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3584:          savm=oldm;
                   3585:          oldm=newm;
                   3586:        } /* end mult */
                   3587:        
                   3588:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3589:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3590:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3591:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3592:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3593:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3594:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3595:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3596:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3597:                                 * -stepm/2 to stepm/2 .
                   3598:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3599:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3600:                                 */
1.234     brouard  3601:        s1=s[mw[mi][i]][i];
                   3602:        s2=s[mw[mi+1][i]][i];
                   3603:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3604:        /* bias bh is positive if real duration
                   3605:         * is higher than the multiple of stepm and negative otherwise.
                   3606:         */
                   3607:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3608:        if( s2 > nlstate){ 
                   3609:          /* i.e. if s2 is a death state and if the date of death is known 
                   3610:             then the contribution to the likelihood is the probability to 
                   3611:             die between last step unit time and current  step unit time, 
                   3612:             which is also equal to probability to die before dh 
                   3613:             minus probability to die before dh-stepm . 
                   3614:             In version up to 0.92 likelihood was computed
                   3615:             as if date of death was unknown. Death was treated as any other
                   3616:             health state: the date of the interview describes the actual state
                   3617:             and not the date of a change in health state. The former idea was
                   3618:             to consider that at each interview the state was recorded
                   3619:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3620:             introduced the exact date of death then we should have modified
                   3621:             the contribution of an exact death to the likelihood. This new
                   3622:             contribution is smaller and very dependent of the step unit
                   3623:             stepm. It is no more the probability to die between last interview
                   3624:             and month of death but the probability to survive from last
                   3625:             interview up to one month before death multiplied by the
                   3626:             probability to die within a month. Thanks to Chris
                   3627:             Jackson for correcting this bug.  Former versions increased
                   3628:             mortality artificially. The bad side is that we add another loop
                   3629:             which slows down the processing. The difference can be up to 10%
                   3630:             lower mortality.
                   3631:          */
                   3632:          /* If, at the beginning of the maximization mostly, the
                   3633:             cumulative probability or probability to be dead is
                   3634:             constant (ie = 1) over time d, the difference is equal to
                   3635:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3636:             s1 at precedent wave, to be dead a month before current
                   3637:             wave is equal to probability, being at state s1 at
                   3638:             precedent wave, to be dead at mont of the current
                   3639:             wave. Then the observed probability (that this person died)
                   3640:             is null according to current estimated parameter. In fact,
                   3641:             it should be very low but not zero otherwise the log go to
                   3642:             infinity.
                   3643:          */
1.183     brouard  3644: /* #ifdef INFINITYORIGINAL */
                   3645: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3646: /* #else */
                   3647: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3648: /*         lli=log(mytinydouble); */
                   3649: /*       else */
                   3650: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3651: /* #endif */
1.226     brouard  3652:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3653:          
1.226     brouard  3654:        } else if  ( s2==-1 ) { /* alive */
                   3655:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3656:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3657:          /*survp += out[s1][j]; */
                   3658:          lli= log(survp);
                   3659:        }
                   3660:        else if  (s2==-4) { 
                   3661:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3662:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3663:          lli= log(survp); 
                   3664:        } 
                   3665:        else if  (s2==-5) { 
                   3666:          for (j=1,survp=0. ; j<=2; j++)  
                   3667:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3668:          lli= log(survp); 
                   3669:        } 
                   3670:        else{
                   3671:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3672:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3673:        } 
                   3674:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3675:        /*if(lli ==000.0)*/
                   3676:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3677:        ipmx +=1;
                   3678:        sw += weight[i];
                   3679:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3680:        /* if (lli < log(mytinydouble)){ */
                   3681:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3682:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3683:        /* } */
                   3684:       } /* end of wave */
                   3685:     } /* end of individual */
                   3686:   }  else if(mle==2){
                   3687:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3688:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3689:       for(mi=1; mi<= wav[i]-1; mi++){
                   3690:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3691:          for (j=1;j<=nlstate+ndeath;j++){
                   3692:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3693:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3694:          }
                   3695:        for(d=0; d<=dh[mi][i]; d++){
                   3696:          newm=savm;
                   3697:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3698:          cov[2]=agexact;
                   3699:          if(nagesqr==1)
                   3700:            cov[3]= agexact*agexact;
                   3701:          for (kk=1; kk<=cptcovage;kk++) {
                   3702:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3703:          }
                   3704:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3705:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3706:          savm=oldm;
                   3707:          oldm=newm;
                   3708:        } /* end mult */
                   3709:       
                   3710:        s1=s[mw[mi][i]][i];
                   3711:        s2=s[mw[mi+1][i]][i];
                   3712:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3713:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3714:        ipmx +=1;
                   3715:        sw += weight[i];
                   3716:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3717:       } /* end of wave */
                   3718:     } /* end of individual */
                   3719:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3720:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3721:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3722:       for(mi=1; mi<= wav[i]-1; mi++){
                   3723:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3724:          for (j=1;j<=nlstate+ndeath;j++){
                   3725:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3726:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3727:          }
                   3728:        for(d=0; d<dh[mi][i]; d++){
                   3729:          newm=savm;
                   3730:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3731:          cov[2]=agexact;
                   3732:          if(nagesqr==1)
                   3733:            cov[3]= agexact*agexact;
                   3734:          for (kk=1; kk<=cptcovage;kk++) {
                   3735:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3736:          }
                   3737:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3738:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3739:          savm=oldm;
                   3740:          oldm=newm;
                   3741:        } /* end mult */
                   3742:       
                   3743:        s1=s[mw[mi][i]][i];
                   3744:        s2=s[mw[mi+1][i]][i];
                   3745:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3746:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3747:        ipmx +=1;
                   3748:        sw += weight[i];
                   3749:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3750:       } /* end of wave */
                   3751:     } /* end of individual */
                   3752:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3753:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3754:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3755:       for(mi=1; mi<= wav[i]-1; mi++){
                   3756:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3757:          for (j=1;j<=nlstate+ndeath;j++){
                   3758:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3759:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3760:          }
                   3761:        for(d=0; d<dh[mi][i]; d++){
                   3762:          newm=savm;
                   3763:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3764:          cov[2]=agexact;
                   3765:          if(nagesqr==1)
                   3766:            cov[3]= agexact*agexact;
                   3767:          for (kk=1; kk<=cptcovage;kk++) {
                   3768:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3769:          }
1.126     brouard  3770:        
1.226     brouard  3771:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3772:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3773:          savm=oldm;
                   3774:          oldm=newm;
                   3775:        } /* end mult */
                   3776:       
                   3777:        s1=s[mw[mi][i]][i];
                   3778:        s2=s[mw[mi+1][i]][i];
                   3779:        if( s2 > nlstate){ 
                   3780:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3781:        } else if  ( s2==-1 ) { /* alive */
                   3782:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3783:            survp += out[s1][j];
                   3784:          lli= log(survp);
                   3785:        }else{
                   3786:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3787:        }
                   3788:        ipmx +=1;
                   3789:        sw += weight[i];
                   3790:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3791: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3792:       } /* end of wave */
                   3793:     } /* end of individual */
                   3794:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3795:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3796:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3797:       for(mi=1; mi<= wav[i]-1; mi++){
                   3798:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3799:          for (j=1;j<=nlstate+ndeath;j++){
                   3800:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3801:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3802:          }
                   3803:        for(d=0; d<dh[mi][i]; d++){
                   3804:          newm=savm;
                   3805:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3806:          cov[2]=agexact;
                   3807:          if(nagesqr==1)
                   3808:            cov[3]= agexact*agexact;
                   3809:          for (kk=1; kk<=cptcovage;kk++) {
                   3810:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3811:          }
1.126     brouard  3812:        
1.226     brouard  3813:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3814:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3815:          savm=oldm;
                   3816:          oldm=newm;
                   3817:        } /* end mult */
                   3818:       
                   3819:        s1=s[mw[mi][i]][i];
                   3820:        s2=s[mw[mi+1][i]][i];
                   3821:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3822:        ipmx +=1;
                   3823:        sw += weight[i];
                   3824:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3825:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3826:       } /* end of wave */
                   3827:     } /* end of individual */
                   3828:   } /* End of if */
                   3829:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3830:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3831:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3832:   return -l;
1.126     brouard  3833: }
                   3834: 
                   3835: /*************** log-likelihood *************/
                   3836: double funcone( double *x)
                   3837: {
1.228     brouard  3838:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3839:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3840:   int ioffset=0;
1.131     brouard  3841:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3842:   double **out;
                   3843:   double lli; /* Individual log likelihood */
                   3844:   double llt;
                   3845:   int s1, s2;
1.228     brouard  3846:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3847: 
1.126     brouard  3848:   double bbh, survp;
1.187     brouard  3849:   double agexact;
1.214     brouard  3850:   double agebegin, ageend;
1.126     brouard  3851:   /*extern weight */
                   3852:   /* We are differentiating ll according to initial status */
                   3853:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3854:   /*for(i=1;i<imx;i++) 
                   3855:     printf(" %d\n",s[4][i]);
                   3856:   */
                   3857:   cov[1]=1.;
                   3858: 
                   3859:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3860:   ioffset=0;
                   3861:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3862:     /* ioffset=2+nagesqr+cptcovage; */
                   3863:     ioffset=2+nagesqr;
1.232     brouard  3864:     /* Fixed */
1.224     brouard  3865:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3866:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
1.311     brouard  3867:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products *//* Missing values are set to -1 but should be dropped */
1.232     brouard  3868:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3869: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3870: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3871: /*    cov[2+6]=covar[2][i]; V2  */
                   3872: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3873: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3874: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3875: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3876: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3877: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3878:     }
1.232     brouard  3879:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3880:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3881:     /* } */
1.231     brouard  3882:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3883:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3884:     /* } */
1.225     brouard  3885:     
1.233     brouard  3886: 
                   3887:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3888:     /* Wave varying (but not age varying) */
                   3889:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3890:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3891:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3892:       }
1.232     brouard  3893:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3894:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3895:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3896:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3897:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3898:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3899:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3900:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3901:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3902:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3903:       /* } */
1.126     brouard  3904:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3905:        for (j=1;j<=nlstate+ndeath;j++){
                   3906:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3907:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3908:        }
1.214     brouard  3909:       
                   3910:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3911:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3912:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3913:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3914:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3915:          and mw[mi+1][i]. dh depends on stepm.*/
                   3916:        newm=savm;
1.247     brouard  3917:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3918:        cov[2]=agexact;
                   3919:        if(nagesqr==1)
                   3920:          cov[3]= agexact*agexact;
                   3921:        for (kk=1; kk<=cptcovage;kk++) {
                   3922:          if(!FixedV[Tvar[Tage[kk]]])
                   3923:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3924:          else
                   3925:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3926:        }
                   3927:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3928:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3929:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3930:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3931:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3932:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3933:        savm=oldm;
                   3934:        oldm=newm;
1.126     brouard  3935:       } /* end mult */
                   3936:       
                   3937:       s1=s[mw[mi][i]][i];
                   3938:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3939:       /* if(s2==-1){ */
1.268     brouard  3940:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3941:       /*       /\* exit(1); *\/ */
                   3942:       /* } */
1.126     brouard  3943:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3944:       /* bias is positive if real duration
                   3945:        * is higher than the multiple of stepm and negative otherwise.
                   3946:        */
                   3947:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3948:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3949:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3950:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3951:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3952:        lli= log(survp);
1.126     brouard  3953:       }else if (mle==1){
1.242     brouard  3954:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3955:       } else if(mle==2){
1.242     brouard  3956:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3957:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3958:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3959:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3960:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3961:       } else{  /* mle=0 back to 1 */
1.242     brouard  3962:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3963:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3964:       } /* End of if */
                   3965:       ipmx +=1;
                   3966:       sw += weight[i];
                   3967:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3968:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3969:       if(globpr){
1.246     brouard  3970:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3971:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3972:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3973:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3974:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3975:          llt +=ll[k]*gipmx/gsw;
                   3976:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3977:        }
                   3978:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3979:       }
1.232     brouard  3980:        } /* end of wave */
                   3981: } /* end of individual */
                   3982: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3983: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3984: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3985: if(globpr==0){ /* First time we count the contributions and weights */
                   3986:        gipmx=ipmx;
                   3987:        gsw=sw;
                   3988: }
                   3989: return -l;
1.126     brouard  3990: }
                   3991: 
                   3992: 
                   3993: /*************** function likelione ***********/
1.292     brouard  3994: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*func)(double []))
1.126     brouard  3995: {
                   3996:   /* This routine should help understanding what is done with 
                   3997:      the selection of individuals/waves and
                   3998:      to check the exact contribution to the likelihood.
                   3999:      Plotting could be done.
                   4000:    */
                   4001:   int k;
                   4002: 
                   4003:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  4004:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  4005:     strcat(fileresilk,fileresu);
1.126     brouard  4006:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   4007:       printf("Problem with resultfile: %s\n", fileresilk);
                   4008:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   4009:     }
1.214     brouard  4010:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   4011:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  4012:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   4013:     for(k=1; k<=nlstate; k++) 
                   4014:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   4015:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   4016:   }
                   4017: 
1.292     brouard  4018:   *fretone=(*func)(p);
1.126     brouard  4019:   if(*globpri !=0){
                   4020:     fclose(ficresilk);
1.205     brouard  4021:     if (mle ==0)
                   4022:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   4023:     else if(mle >=1)
                   4024:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   4025:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  4026:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  4027:       
                   4028:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  4029:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  4030: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   4031:     }
1.207     brouard  4032:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  4033: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4034:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  4035: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4036:     fflush(fichtm);
1.205     brouard  4037:   }
1.126     brouard  4038:   return;
                   4039: }
                   4040: 
                   4041: 
                   4042: /*********** Maximum Likelihood Estimation ***************/
                   4043: 
                   4044: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   4045: {
1.165     brouard  4046:   int i,j, iter=0;
1.126     brouard  4047:   double **xi;
                   4048:   double fret;
                   4049:   double fretone; /* Only one call to likelihood */
                   4050:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  4051: 
                   4052: #ifdef NLOPT
                   4053:   int creturn;
                   4054:   nlopt_opt opt;
                   4055:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   4056:   double *lb;
                   4057:   double minf; /* the minimum objective value, upon return */
                   4058:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   4059:   myfunc_data dinst, *d = &dinst;
                   4060: #endif
                   4061: 
                   4062: 
1.126     brouard  4063:   xi=matrix(1,npar,1,npar);
                   4064:   for (i=1;i<=npar;i++)
                   4065:     for (j=1;j<=npar;j++)
                   4066:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   4067:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  4068:   strcpy(filerespow,"POW_"); 
1.126     brouard  4069:   strcat(filerespow,fileres);
                   4070:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   4071:     printf("Problem with resultfile: %s\n", filerespow);
                   4072:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   4073:   }
                   4074:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   4075:   for (i=1;i<=nlstate;i++)
                   4076:     for(j=1;j<=nlstate+ndeath;j++)
                   4077:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   4078:   fprintf(ficrespow,"\n");
1.162     brouard  4079: #ifdef POWELL
1.126     brouard  4080:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  4081: #endif
1.126     brouard  4082: 
1.162     brouard  4083: #ifdef NLOPT
                   4084: #ifdef NEWUOA
                   4085:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   4086: #else
                   4087:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   4088: #endif
                   4089:   lb=vector(0,npar-1);
                   4090:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   4091:   nlopt_set_lower_bounds(opt, lb);
                   4092:   nlopt_set_initial_step1(opt, 0.1);
                   4093:   
                   4094:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   4095:   d->function = func;
                   4096:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   4097:   nlopt_set_min_objective(opt, myfunc, d);
                   4098:   nlopt_set_xtol_rel(opt, ftol);
                   4099:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   4100:     printf("nlopt failed! %d\n",creturn); 
                   4101:   }
                   4102:   else {
                   4103:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4104:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4105:     iter=1; /* not equal */
                   4106:   }
                   4107:   nlopt_destroy(opt);
                   4108: #endif
1.126     brouard  4109:   free_matrix(xi,1,npar,1,npar);
                   4110:   fclose(ficrespow);
1.203     brouard  4111:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4112:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4113:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4114: 
                   4115: }
                   4116: 
                   4117: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4118: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4119: {
                   4120:   double  **a,**y,*x,pd;
1.203     brouard  4121:   /* double **hess; */
1.164     brouard  4122:   int i, j;
1.126     brouard  4123:   int *indx;
                   4124: 
                   4125:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4126:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4127:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4128:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4129:   double gompertz(double p[]);
1.203     brouard  4130:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4131: 
                   4132:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4133:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4134:   for (i=1;i<=npar;i++){
1.203     brouard  4135:     printf("%d-",i);fflush(stdout);
                   4136:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4137:    
                   4138:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4139:     
                   4140:     /*  printf(" %f ",p[i]);
                   4141:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4142:   }
                   4143:   
                   4144:   for (i=1;i<=npar;i++) {
                   4145:     for (j=1;j<=npar;j++)  {
                   4146:       if (j>i) { 
1.203     brouard  4147:        printf(".%d-%d",i,j);fflush(stdout);
                   4148:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4149:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4150:        
                   4151:        hess[j][i]=hess[i][j];    
                   4152:        /*printf(" %lf ",hess[i][j]);*/
                   4153:       }
                   4154:     }
                   4155:   }
                   4156:   printf("\n");
                   4157:   fprintf(ficlog,"\n");
                   4158: 
                   4159:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4160:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4161:   
                   4162:   a=matrix(1,npar,1,npar);
                   4163:   y=matrix(1,npar,1,npar);
                   4164:   x=vector(1,npar);
                   4165:   indx=ivector(1,npar);
                   4166:   for (i=1;i<=npar;i++)
                   4167:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4168:   ludcmp(a,npar,indx,&pd);
                   4169: 
                   4170:   for (j=1;j<=npar;j++) {
                   4171:     for (i=1;i<=npar;i++) x[i]=0;
                   4172:     x[j]=1;
                   4173:     lubksb(a,npar,indx,x);
                   4174:     for (i=1;i<=npar;i++){ 
                   4175:       matcov[i][j]=x[i];
                   4176:     }
                   4177:   }
                   4178: 
                   4179:   printf("\n#Hessian matrix#\n");
                   4180:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4181:   for (i=1;i<=npar;i++) { 
                   4182:     for (j=1;j<=npar;j++) { 
1.203     brouard  4183:       printf("%.6e ",hess[i][j]);
                   4184:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4185:     }
                   4186:     printf("\n");
                   4187:     fprintf(ficlog,"\n");
                   4188:   }
                   4189: 
1.203     brouard  4190:   /* printf("\n#Covariance matrix#\n"); */
                   4191:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4192:   /* for (i=1;i<=npar;i++) {  */
                   4193:   /*   for (j=1;j<=npar;j++) {  */
                   4194:   /*     printf("%.6e ",matcov[i][j]); */
                   4195:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4196:   /*   } */
                   4197:   /*   printf("\n"); */
                   4198:   /*   fprintf(ficlog,"\n"); */
                   4199:   /* } */
                   4200: 
1.126     brouard  4201:   /* Recompute Inverse */
1.203     brouard  4202:   /* for (i=1;i<=npar;i++) */
                   4203:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4204:   /* ludcmp(a,npar,indx,&pd); */
                   4205: 
                   4206:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4207: 
                   4208:   /* for (j=1;j<=npar;j++) { */
                   4209:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4210:   /*   x[j]=1; */
                   4211:   /*   lubksb(a,npar,indx,x); */
                   4212:   /*   for (i=1;i<=npar;i++){  */
                   4213:   /*     y[i][j]=x[i]; */
                   4214:   /*     printf("%.3e ",y[i][j]); */
                   4215:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4216:   /*   } */
                   4217:   /*   printf("\n"); */
                   4218:   /*   fprintf(ficlog,"\n"); */
                   4219:   /* } */
                   4220: 
                   4221:   /* Verifying the inverse matrix */
                   4222: #ifdef DEBUGHESS
                   4223:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4224: 
1.203     brouard  4225:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4226:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4227: 
                   4228:   for (j=1;j<=npar;j++) {
                   4229:     for (i=1;i<=npar;i++){ 
1.203     brouard  4230:       printf("%.2f ",y[i][j]);
                   4231:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4232:     }
                   4233:     printf("\n");
                   4234:     fprintf(ficlog,"\n");
                   4235:   }
1.203     brouard  4236: #endif
1.126     brouard  4237: 
                   4238:   free_matrix(a,1,npar,1,npar);
                   4239:   free_matrix(y,1,npar,1,npar);
                   4240:   free_vector(x,1,npar);
                   4241:   free_ivector(indx,1,npar);
1.203     brouard  4242:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4243: 
                   4244: 
                   4245: }
                   4246: 
                   4247: /*************** hessian matrix ****************/
                   4248: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4249: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4250:   int i;
                   4251:   int l=1, lmax=20;
1.203     brouard  4252:   double k1,k2, res, fx;
1.132     brouard  4253:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4254:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4255:   int k=0,kmax=10;
                   4256:   double l1;
                   4257: 
                   4258:   fx=func(x);
                   4259:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4260:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4261:     l1=pow(10,l);
                   4262:     delts=delt;
                   4263:     for(k=1 ; k <kmax; k=k+1){
                   4264:       delt = delta*(l1*k);
                   4265:       p2[theta]=x[theta] +delt;
1.145     brouard  4266:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4267:       p2[theta]=x[theta]-delt;
                   4268:       k2=func(p2)-fx;
                   4269:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4270:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4271:       
1.203     brouard  4272: #ifdef DEBUGHESSII
1.126     brouard  4273:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4274:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4275: #endif
                   4276:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4277:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4278:        k=kmax;
                   4279:       }
                   4280:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4281:        k=kmax; l=lmax*10;
1.126     brouard  4282:       }
                   4283:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4284:        delts=delt;
                   4285:       }
1.203     brouard  4286:     } /* End loop k */
1.126     brouard  4287:   }
                   4288:   delti[theta]=delts;
                   4289:   return res; 
                   4290:   
                   4291: }
                   4292: 
1.203     brouard  4293: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4294: {
                   4295:   int i;
1.164     brouard  4296:   int l=1, lmax=20;
1.126     brouard  4297:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4298:   double p2[MAXPARM+1];
1.203     brouard  4299:   int k, kmax=1;
                   4300:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4301: 
                   4302:   int firstime=0;
1.203     brouard  4303:   
1.126     brouard  4304:   fx=func(x);
1.203     brouard  4305:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4306:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4307:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4308:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4309:     k1=func(p2)-fx;
                   4310:   
1.203     brouard  4311:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4312:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4313:     k2=func(p2)-fx;
                   4314:   
1.203     brouard  4315:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4316:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4317:     k3=func(p2)-fx;
                   4318:   
1.203     brouard  4319:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4320:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4321:     k4=func(p2)-fx;
1.203     brouard  4322:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4323:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4324:       firstime=1;
1.203     brouard  4325:       kmax=kmax+10;
1.208     brouard  4326:     }
                   4327:     if(kmax >=10 || firstime ==1){
1.246     brouard  4328:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4329:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4330:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4331:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4332:     }
                   4333: #ifdef DEBUGHESSIJ
                   4334:     v1=hess[thetai][thetai];
                   4335:     v2=hess[thetaj][thetaj];
                   4336:     cv12=res;
                   4337:     /* Computing eigen value of Hessian matrix */
                   4338:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4339:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4340:     if ((lc2 <0) || (lc1 <0) ){
                   4341:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4342:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4343:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4344:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4345:     }
1.126     brouard  4346: #endif
                   4347:   }
                   4348:   return res;
                   4349: }
                   4350: 
1.203     brouard  4351:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4352: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4353: /* { */
                   4354: /*   int i; */
                   4355: /*   int l=1, lmax=20; */
                   4356: /*   double k1,k2,k3,k4,res,fx; */
                   4357: /*   double p2[MAXPARM+1]; */
                   4358: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4359: /*   int k=0,kmax=10; */
                   4360: /*   double l1; */
                   4361:   
                   4362: /*   fx=func(x); */
                   4363: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4364: /*     l1=pow(10,l); */
                   4365: /*     delts=delt; */
                   4366: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4367: /*       delt = delti*(l1*k); */
                   4368: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4369: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4370: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4371: /*       k1=func(p2)-fx; */
                   4372:       
                   4373: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4374: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4375: /*       k2=func(p2)-fx; */
                   4376:       
                   4377: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4378: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4379: /*       k3=func(p2)-fx; */
                   4380:       
                   4381: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4382: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4383: /*       k4=func(p2)-fx; */
                   4384: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4385: /* #ifdef DEBUGHESSIJ */
                   4386: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4387: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4388: /* #endif */
                   4389: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4390: /*     k=kmax; */
                   4391: /*       } */
                   4392: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4393: /*     k=kmax; l=lmax*10; */
                   4394: /*       } */
                   4395: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4396: /*     delts=delt; */
                   4397: /*       } */
                   4398: /*     } /\* End loop k *\/ */
                   4399: /*   } */
                   4400: /*   delti[theta]=delts; */
                   4401: /*   return res;  */
                   4402: /* } */
                   4403: 
                   4404: 
1.126     brouard  4405: /************** Inverse of matrix **************/
                   4406: void ludcmp(double **a, int n, int *indx, double *d) 
                   4407: { 
                   4408:   int i,imax,j,k; 
                   4409:   double big,dum,sum,temp; 
                   4410:   double *vv; 
                   4411:  
                   4412:   vv=vector(1,n); 
                   4413:   *d=1.0; 
                   4414:   for (i=1;i<=n;i++) { 
                   4415:     big=0.0; 
                   4416:     for (j=1;j<=n;j++) 
                   4417:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4418:     if (big == 0.0){
                   4419:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4420:       for (j=1;j<=n;j++) {
                   4421:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4422:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4423:       }
                   4424:       fflush(ficlog);
                   4425:       fclose(ficlog);
                   4426:       nrerror("Singular matrix in routine ludcmp"); 
                   4427:     }
1.126     brouard  4428:     vv[i]=1.0/big; 
                   4429:   } 
                   4430:   for (j=1;j<=n;j++) { 
                   4431:     for (i=1;i<j;i++) { 
                   4432:       sum=a[i][j]; 
                   4433:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4434:       a[i][j]=sum; 
                   4435:     } 
                   4436:     big=0.0; 
                   4437:     for (i=j;i<=n;i++) { 
                   4438:       sum=a[i][j]; 
                   4439:       for (k=1;k<j;k++) 
                   4440:        sum -= a[i][k]*a[k][j]; 
                   4441:       a[i][j]=sum; 
                   4442:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4443:        big=dum; 
                   4444:        imax=i; 
                   4445:       } 
                   4446:     } 
                   4447:     if (j != imax) { 
                   4448:       for (k=1;k<=n;k++) { 
                   4449:        dum=a[imax][k]; 
                   4450:        a[imax][k]=a[j][k]; 
                   4451:        a[j][k]=dum; 
                   4452:       } 
                   4453:       *d = -(*d); 
                   4454:       vv[imax]=vv[j]; 
                   4455:     } 
                   4456:     indx[j]=imax; 
                   4457:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4458:     if (j != n) { 
                   4459:       dum=1.0/(a[j][j]); 
                   4460:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4461:     } 
                   4462:   } 
                   4463:   free_vector(vv,1,n);  /* Doesn't work */
                   4464: ;
                   4465: } 
                   4466: 
                   4467: void lubksb(double **a, int n, int *indx, double b[]) 
                   4468: { 
                   4469:   int i,ii=0,ip,j; 
                   4470:   double sum; 
                   4471:  
                   4472:   for (i=1;i<=n;i++) { 
                   4473:     ip=indx[i]; 
                   4474:     sum=b[ip]; 
                   4475:     b[ip]=b[i]; 
                   4476:     if (ii) 
                   4477:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4478:     else if (sum) ii=i; 
                   4479:     b[i]=sum; 
                   4480:   } 
                   4481:   for (i=n;i>=1;i--) { 
                   4482:     sum=b[i]; 
                   4483:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4484:     b[i]=sum/a[i][i]; 
                   4485:   } 
                   4486: } 
                   4487: 
                   4488: void pstamp(FILE *fichier)
                   4489: {
1.196     brouard  4490:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4491: }
                   4492: 
1.297     brouard  4493: void date2dmy(double date,double *day, double *month, double *year){
                   4494:   double yp=0., yp1=0., yp2=0.;
                   4495:   
                   4496:   yp1=modf(date,&yp);/* extracts integral of date in yp  and
                   4497:                        fractional in yp1 */
                   4498:   *year=yp;
                   4499:   yp2=modf((yp1*12),&yp);
                   4500:   *month=yp;
                   4501:   yp1=modf((yp2*30.5),&yp);
                   4502:   *day=yp;
                   4503:   if(*day==0) *day=1;
                   4504:   if(*month==0) *month=1;
                   4505: }
                   4506: 
1.253     brouard  4507: 
                   4508: 
1.126     brouard  4509: /************ Frequencies ********************/
1.251     brouard  4510: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4511:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4512:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4513: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4514:   
1.265     brouard  4515:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4516:   int iind=0, iage=0;
                   4517:   int mi; /* Effective wave */
                   4518:   int first;
                   4519:   double ***freq; /* Frequencies */
1.268     brouard  4520:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4521:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4522:   double *meanq, *stdq, *idq;
1.226     brouard  4523:   double **meanqt;
                   4524:   double *pp, **prop, *posprop, *pospropt;
                   4525:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4526:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4527:   double agebegin, ageend;
                   4528:     
                   4529:   pp=vector(1,nlstate);
1.251     brouard  4530:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4531:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4532:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4533:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4534:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4535:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4536:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4537:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4538:   strcpy(fileresp,"P_");
                   4539:   strcat(fileresp,fileresu);
                   4540:   /*strcat(fileresphtm,fileresu);*/
                   4541:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4542:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4543:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4544:     exit(0);
                   4545:   }
1.240     brouard  4546:   
1.226     brouard  4547:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4548:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4549:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4550:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4551:     fflush(ficlog);
                   4552:     exit(70); 
                   4553:   }
                   4554:   else{
                   4555:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4556: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4557: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4558:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4559:   }
1.237     brouard  4560:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4561:   
1.226     brouard  4562:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4563:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4564:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4565:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4566:     fflush(ficlog);
                   4567:     exit(70); 
1.240     brouard  4568:   } else{
1.226     brouard  4569:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4570: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4571: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4572:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4573:   }
1.240     brouard  4574:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4575:   
1.253     brouard  4576:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4577:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4578:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4579:   j1=0;
1.126     brouard  4580:   
1.227     brouard  4581:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4582:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4583:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4584:   
                   4585:   
1.226     brouard  4586:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4587:      reference=low_education V1=0,V2=0
                   4588:      med_educ                V1=1 V2=0, 
                   4589:      high_educ               V1=0 V2=1
                   4590:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4591:   */
1.249     brouard  4592:   dateintsum=0;
                   4593:   k2cpt=0;
                   4594: 
1.253     brouard  4595:   if(cptcoveff == 0 )
1.265     brouard  4596:     nl=1;  /* Constant and age model only */
1.253     brouard  4597:   else
                   4598:     nl=2;
1.265     brouard  4599: 
                   4600:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4601:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4602:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4603:    *     freq[s1][s2][iage] =0.
                   4604:    *     Loop on iind
                   4605:    *       ++freq[s1][s2][iage] weighted
                   4606:    *     end iind
                   4607:    *     if covariate and j!0
                   4608:    *       headers Variable on one line
                   4609:    *     endif cov j!=0
                   4610:    *     header of frequency table by age
                   4611:    *     Loop on age
                   4612:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4613:    *       pos+=freq[s1][s2][iage] weighted
                   4614:    *       Loop on s1 initial state
                   4615:    *         fprintf(ficresp
                   4616:    *       end s1
                   4617:    *     end age
                   4618:    *     if j!=0 computes starting values
                   4619:    *     end compute starting values
                   4620:    *   end j1
                   4621:    * end nl 
                   4622:    */
1.253     brouard  4623:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4624:     if(nj==1)
                   4625:       j=0;  /* First pass for the constant */
1.265     brouard  4626:     else{
1.253     brouard  4627:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4628:     }
1.251     brouard  4629:     first=1;
1.265     brouard  4630:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4631:       posproptt=0.;
                   4632:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4633:        scanf("%d", i);*/
                   4634:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4635:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4636:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4637:            freq[i][s2][m]=0;
1.251     brouard  4638:       
                   4639:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4640:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4641:          prop[i][m]=0;
                   4642:        posprop[i]=0;
                   4643:        pospropt[i]=0;
                   4644:       }
1.283     brouard  4645:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4646:         idq[z1]=0.;
                   4647:         meanq[z1]=0.;
                   4648:         stdq[z1]=0.;
1.283     brouard  4649:       }
                   4650:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4651:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4652:       /*         meanqt[m][z1]=0.; */
                   4653:       /*       } */
                   4654:       /* }       */
1.251     brouard  4655:       /* dateintsum=0; */
                   4656:       /* k2cpt=0; */
                   4657:       
1.265     brouard  4658:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4659:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4660:        bool=1;
                   4661:        if(j !=0){
                   4662:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4663:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4664:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4665:                /* if(Tvaraff[z1] ==-20){ */
                   4666:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4667:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4668:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4669:                /* }else  */
                   4670:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4671:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4672:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4673:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4674:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4675:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4676:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4677:                } /* Onlyf fixed */
                   4678:              } /* end z1 */
                   4679:            } /* cptcovn > 0 */
                   4680:          } /* end any */
                   4681:        }/* end j==0 */
1.265     brouard  4682:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4683:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4684:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4685:            m=mw[mi][iind];
                   4686:            if(j!=0){
                   4687:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4688:                for (z1=1; z1<=cptcoveff; z1++) {
                   4689:                  if( Fixed[Tmodelind[z1]]==1){
                   4690:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4691:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4692:                                                                                      value is -1, we don't select. It differs from the 
                   4693:                                                                                      constant and age model which counts them. */
                   4694:                      bool=0; /* not selected */
                   4695:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4696:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4697:                      bool=0;
                   4698:                    }
                   4699:                  }
                   4700:                }
                   4701:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4702:            } /* end j==0 */
                   4703:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4704:            if(bool==1){ /*Selected */
1.251     brouard  4705:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4706:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4707:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4708:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4709:              if(m >=firstpass && m <=lastpass){
                   4710:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4711:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4712:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4713:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4714:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4715:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4716:                if (m<lastpass) {
                   4717:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4718:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4719:                  if(s[m][iind]==-1)
                   4720:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4721:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.311     brouard  4722:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean on known values only */
                   4723:                    if(!isnan(covar[ncovcol+z1][iind])){
                   4724:                        idq[z1]=idq[z1]+weight[iind];
                   4725:                        meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4726:                        /* stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; *//*error*/
                   4727:                        stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4728:                    }
1.284     brouard  4729:                  }
1.251     brouard  4730:                  /* if((int)agev[m][iind] == 55) */
                   4731:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4732:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4733:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4734:                }
1.251     brouard  4735:              } /* end if between passes */  
                   4736:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4737:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4738:                k2cpt++;
                   4739:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4740:              }
1.251     brouard  4741:            }else{
                   4742:              bool=1;
                   4743:            }/* end bool 2 */
                   4744:          } /* end m */
1.284     brouard  4745:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4746:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4747:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4748:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4749:          /* } */
1.251     brouard  4750:        } /* end bool */
                   4751:       } /* end iind = 1 to imx */
                   4752:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4753:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4754:       
                   4755:       
                   4756:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4757:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4758:         pstamp(ficresp);
1.251     brouard  4759:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4760:         pstamp(ficresp);
1.251     brouard  4761:        printf( "\n#********** Variable "); 
                   4762:        fprintf(ficresp, "\n#********** Variable "); 
                   4763:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4764:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4765:        fprintf(ficlog, "\n#********** Variable "); 
                   4766:        for (z1=1; z1<=cptcoveff; z1++){
                   4767:          if(!FixedV[Tvaraff[z1]]){
                   4768:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4769:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4770:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4771:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4772:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4773:          }else{
1.251     brouard  4774:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4775:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4776:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4777:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4778:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4779:          }
                   4780:        }
                   4781:        printf( "**********\n#");
                   4782:        fprintf(ficresp, "**********\n#");
                   4783:        fprintf(ficresphtm, "**********</h3>\n");
                   4784:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4785:        fprintf(ficlog, "**********\n");
                   4786:       }
1.284     brouard  4787:       /*
                   4788:        Printing means of quantitative variables if any
                   4789:       */
                   4790:       for (z1=1; z1<= nqfveff; z1++) {
1.311     brouard  4791:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.3g (weighted) individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.312     brouard  4792:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
1.284     brouard  4793:        if(weightopt==1){
                   4794:          printf(" Weighted mean and standard deviation of");
                   4795:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4796:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4797:        }
1.311     brouard  4798:        /* mu = \frac{w x}{\sum w}
                   4799:            var = \frac{\sum w (x-mu)^2}{\sum w} = \frac{w x^2}{\sum w} - mu^2 
                   4800:        */
                   4801:        printf(" fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   4802:        fprintf(ficlog," fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   4803:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.3g (weighted) representatives of the population : %8.5g (%8.5g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
1.284     brouard  4804:       }
                   4805:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4806:       /*       for(m=1;m<=lastpass;m++){ */
                   4807:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4808:       /*   } */
                   4809:       /* } */
1.283     brouard  4810: 
1.251     brouard  4811:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4812:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4813:         fprintf(ficresp, " Age");
                   4814:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4815:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4816:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4817:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4818:       }
1.265     brouard  4819:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4820:       fprintf(ficresphtm, "\n");
                   4821:       
                   4822:       /* Header of frequency table by age */
                   4823:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4824:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4825:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4826:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4827:          if(s2!=0 && m!=0)
                   4828:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4829:        }
1.226     brouard  4830:       }
1.251     brouard  4831:       fprintf(ficresphtmfr, "\n");
                   4832:     
                   4833:       /* For each age */
                   4834:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4835:        fprintf(ficresphtm,"<tr>");
                   4836:        if(iage==iagemax+1){
                   4837:          fprintf(ficlog,"1");
                   4838:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4839:        }else if(iage==iagemax+2){
                   4840:          fprintf(ficlog,"0");
                   4841:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4842:        }else if(iage==iagemax+3){
                   4843:          fprintf(ficlog,"Total");
                   4844:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4845:        }else{
1.240     brouard  4846:          if(first==1){
1.251     brouard  4847:            first=0;
                   4848:            printf("See log file for details...\n");
                   4849:          }
                   4850:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4851:          fprintf(ficlog,"Age %d", iage);
                   4852:        }
1.265     brouard  4853:        for(s1=1; s1 <=nlstate ; s1++){
                   4854:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4855:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4856:        }
1.265     brouard  4857:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4858:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4859:            pos += freq[s1][m][iage];
                   4860:          if(pp[s1]>=1.e-10){
1.251     brouard  4861:            if(first==1){
1.265     brouard  4862:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4863:            }
1.265     brouard  4864:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4865:          }else{
                   4866:            if(first==1)
1.265     brouard  4867:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4868:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4869:          }
                   4870:        }
                   4871:       
1.265     brouard  4872:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4873:          /* posprop[s1]=0; */
                   4874:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4875:            pp[s1] += freq[s1][m][iage];
                   4876:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4877:       
                   4878:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4879:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4880:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4881:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4882:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4883:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4884:        }
                   4885:        
                   4886:        /* Writing ficresp */
                   4887:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4888:           if( iage <= iagemax){
                   4889:            fprintf(ficresp," %d",iage);
                   4890:           }
                   4891:         }else if( nj==2){
                   4892:           if( iage <= iagemax){
                   4893:            fprintf(ficresp," %d",iage);
                   4894:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4895:           }
1.240     brouard  4896:        }
1.265     brouard  4897:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4898:          if(pos>=1.e-5){
1.251     brouard  4899:            if(first==1)
1.265     brouard  4900:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4901:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4902:          }else{
                   4903:            if(first==1)
1.265     brouard  4904:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4905:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4906:          }
                   4907:          if( iage <= iagemax){
                   4908:            if(pos>=1.e-5){
1.265     brouard  4909:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4910:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4911:               }else if( nj==2){
                   4912:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4913:               }
                   4914:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4915:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4916:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4917:            } else{
                   4918:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4919:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4920:            }
1.240     brouard  4921:          }
1.265     brouard  4922:          pospropt[s1] +=posprop[s1];
                   4923:        } /* end loop s1 */
1.251     brouard  4924:        /* pospropt=0.; */
1.265     brouard  4925:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4926:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4927:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4928:              if(first==1){
1.265     brouard  4929:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4930:              }
1.265     brouard  4931:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4932:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4933:            }
1.265     brouard  4934:            if(s1!=0 && m!=0)
                   4935:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4936:          }
1.265     brouard  4937:        } /* end loop s1 */
1.251     brouard  4938:        posproptt=0.; 
1.265     brouard  4939:        for(s1=1; s1 <=nlstate; s1++){
                   4940:          posproptt += pospropt[s1];
1.251     brouard  4941:        }
                   4942:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4943:        fprintf(ficresphtm,"</tr>\n");
                   4944:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4945:          if(iage <= iagemax)
                   4946:            fprintf(ficresp,"\n");
1.240     brouard  4947:        }
1.251     brouard  4948:        if(first==1)
                   4949:          printf("Others in log...\n");
                   4950:        fprintf(ficlog,"\n");
                   4951:       } /* end loop age iage */
1.265     brouard  4952:       
1.251     brouard  4953:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4954:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4955:        if(posproptt < 1.e-5){
1.265     brouard  4956:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4957:        }else{
1.265     brouard  4958:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4959:        }
1.226     brouard  4960:       }
1.251     brouard  4961:       fprintf(ficresphtm,"</tr>\n");
                   4962:       fprintf(ficresphtm,"</table>\n");
                   4963:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4964:       if(posproptt < 1.e-5){
1.251     brouard  4965:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4966:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4967:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4968:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4969:        invalidvarcomb[j1]=1;
1.226     brouard  4970:       }else{
1.251     brouard  4971:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4972:        invalidvarcomb[j1]=0;
1.226     brouard  4973:       }
1.251     brouard  4974:       fprintf(ficresphtmfr,"</table>\n");
                   4975:       fprintf(ficlog,"\n");
                   4976:       if(j!=0){
                   4977:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4978:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4979:          for(k=1; k <=(nlstate+ndeath); k++){
                   4980:            if (k != i) {
1.265     brouard  4981:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4982:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4983:                  if(j1==1){ /* All dummy covariates to zero */
                   4984:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4985:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4986:                    printf("%d%d ",i,k);
                   4987:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4988:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4989:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4990:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4991:                  }
1.253     brouard  4992:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4993:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4994:                    x[iage]= (double)iage;
                   4995:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4996:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4997:                  }
1.268     brouard  4998:                  /* Some are not finite, but linreg will ignore these ages */
                   4999:                  no=0;
1.253     brouard  5000:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  5001:                  pstart[s1]=b;
                   5002:                  pstart[s1-1]=a;
1.252     brouard  5003:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   5004:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   5005:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  5006:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  5007:                  printf("%d%d ",i,k);
                   5008:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  5009:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  5010:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   5011:                  ;
                   5012:                }
                   5013:                /* printf("%12.7f )", param[i][jj][k]); */
                   5014:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5015:                s1++; 
1.251     brouard  5016:              } /* end jj */
                   5017:            } /* end k!= i */
                   5018:          } /* end k */
1.265     brouard  5019:        } /* end i, s1 */
1.251     brouard  5020:       } /* end j !=0 */
                   5021:     } /* end selected combination of covariate j1 */
                   5022:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   5023:       printf("#Freqsummary: Starting values for the constants:\n");
                   5024:       fprintf(ficlog,"\n");
1.265     brouard  5025:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  5026:        for(k=1; k <=(nlstate+ndeath); k++){
                   5027:          if (k != i) {
                   5028:            printf("%d%d ",i,k);
                   5029:            fprintf(ficlog,"%d%d ",i,k);
                   5030:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  5031:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  5032:              if(jj==1){ /* Age has to be done */
1.265     brouard  5033:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   5034:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   5035:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  5036:              }
                   5037:              /* printf("%12.7f )", param[i][jj][k]); */
                   5038:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5039:              s1++; 
1.250     brouard  5040:            }
1.251     brouard  5041:            printf("\n");
                   5042:            fprintf(ficlog,"\n");
1.250     brouard  5043:          }
                   5044:        }
1.284     brouard  5045:       } /* end of state i */
1.251     brouard  5046:       printf("#Freqsummary\n");
                   5047:       fprintf(ficlog,"\n");
1.265     brouard  5048:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   5049:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   5050:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   5051:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5052:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5053:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   5054:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   5055:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  5056:          /* } */
                   5057:        }
1.265     brouard  5058:       } /* end loop s1 */
1.251     brouard  5059:       
                   5060:       printf("\n");
                   5061:       fprintf(ficlog,"\n");
                   5062:     } /* end j=0 */
1.249     brouard  5063:   } /* end j */
1.252     brouard  5064: 
1.253     brouard  5065:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  5066:     for(i=1, jk=1; i <=nlstate; i++){
                   5067:       for(j=1; j <=nlstate+ndeath; j++){
                   5068:        if(j!=i){
                   5069:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   5070:          printf("%1d%1d",i,j);
                   5071:          fprintf(ficparo,"%1d%1d",i,j);
                   5072:          for(k=1; k<=ncovmodel;k++){
                   5073:            /*    printf(" %lf",param[i][j][k]); */
                   5074:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   5075:            p[jk]=pstart[jk];
                   5076:            printf(" %f ",pstart[jk]);
                   5077:            fprintf(ficparo," %f ",pstart[jk]);
                   5078:            jk++;
                   5079:          }
                   5080:          printf("\n");
                   5081:          fprintf(ficparo,"\n");
                   5082:        }
                   5083:       }
                   5084:     }
                   5085:   } /* end mle=-2 */
1.226     brouard  5086:   dateintmean=dateintsum/k2cpt; 
1.296     brouard  5087:   date2dmy(dateintmean,&jintmean,&mintmean,&aintmean);
1.240     brouard  5088:   
1.226     brouard  5089:   fclose(ficresp);
                   5090:   fclose(ficresphtm);
                   5091:   fclose(ficresphtmfr);
1.283     brouard  5092:   free_vector(idq,1,nqfveff);
1.226     brouard  5093:   free_vector(meanq,1,nqfveff);
1.284     brouard  5094:   free_vector(stdq,1,nqfveff);
1.226     brouard  5095:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  5096:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   5097:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  5098:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5099:   free_vector(pospropt,1,nlstate);
                   5100:   free_vector(posprop,1,nlstate);
1.251     brouard  5101:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5102:   free_vector(pp,1,nlstate);
                   5103:   /* End of freqsummary */
                   5104: }
1.126     brouard  5105: 
1.268     brouard  5106: /* Simple linear regression */
                   5107: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   5108: 
                   5109:   /* y=a+bx regression */
                   5110:   double   sumx = 0.0;                        /* sum of x                      */
                   5111:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   5112:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   5113:   double   sumy = 0.0;                        /* sum of y                      */
                   5114:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   5115:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   5116:   double yhat;
                   5117:   
                   5118:   double denom=0;
                   5119:   int i;
                   5120:   int ne=*no;
                   5121:   
                   5122:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5123:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5124:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5125:       continue;
                   5126:     }
                   5127:     ne=ne+1;
                   5128:     sumx  += x[i];       
                   5129:     sumx2 += x[i]*x[i];  
                   5130:     sumxy += x[i] * y[i];
                   5131:     sumy  += y[i];      
                   5132:     sumy2 += y[i]*y[i]; 
                   5133:     denom = (ne * sumx2 - sumx*sumx);
                   5134:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5135:   } 
                   5136:   
                   5137:   denom = (ne * sumx2 - sumx*sumx);
                   5138:   if (denom == 0) {
                   5139:     // vertical, slope m is infinity
                   5140:     *b = INFINITY;
                   5141:     *a = 0;
                   5142:     if (r) *r = 0;
                   5143:     return 1;
                   5144:   }
                   5145:   
                   5146:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5147:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5148:   if (r!=NULL) {
                   5149:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5150:       sqrt((sumx2 - sumx*sumx/ne) *
                   5151:           (sumy2 - sumy*sumy/ne));
                   5152:   }
                   5153:   *no=ne;
                   5154:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5155:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5156:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5157:       continue;
                   5158:     }
                   5159:     ne=ne+1;
                   5160:     yhat = y[i] - *a -*b* x[i];
                   5161:     sume2  += yhat * yhat ;       
                   5162:     
                   5163:     denom = (ne * sumx2 - sumx*sumx);
                   5164:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5165:   } 
                   5166:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5167:   *sa= *sb * sqrt(sumx2/ne);
                   5168:   
                   5169:   return 0; 
                   5170: }
                   5171: 
1.126     brouard  5172: /************ Prevalence ********************/
1.227     brouard  5173: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5174: {  
                   5175:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5176:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5177:      We still use firstpass and lastpass as another selection.
                   5178:   */
1.126     brouard  5179:  
1.227     brouard  5180:   int i, m, jk, j1, bool, z1,j, iv;
                   5181:   int mi; /* Effective wave */
                   5182:   int iage;
                   5183:   double agebegin, ageend;
                   5184: 
                   5185:   double **prop;
                   5186:   double posprop; 
                   5187:   double  y2; /* in fractional years */
                   5188:   int iagemin, iagemax;
                   5189:   int first; /** to stop verbosity which is redirected to log file */
                   5190: 
                   5191:   iagemin= (int) agemin;
                   5192:   iagemax= (int) agemax;
                   5193:   /*pp=vector(1,nlstate);*/
1.251     brouard  5194:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5195:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5196:   j1=0;
1.222     brouard  5197:   
1.227     brouard  5198:   /*j=cptcoveff;*/
                   5199:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5200:   
1.288     brouard  5201:   first=0;
1.227     brouard  5202:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5203:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5204:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5205:        prop[i][iage]=0.0;
                   5206:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5207:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5208:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5209:     
                   5210:     for (i=1; i<=imx; i++) { /* Each individual */
                   5211:       bool=1;
                   5212:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5213:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5214:        m=mw[mi][i];
                   5215:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5216:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5217:        for (z1=1; z1<=cptcoveff; z1++){
                   5218:          if( Fixed[Tmodelind[z1]]==1){
                   5219:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5220:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5221:              bool=0;
                   5222:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5223:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5224:              bool=0;
                   5225:            }
                   5226:        }
                   5227:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5228:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5229:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5230:          if(m >=firstpass && m <=lastpass){
                   5231:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5232:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5233:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5234:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5235:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5236:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5237:                exit(1);
                   5238:              }
                   5239:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5240:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5241:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5242:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5243:              } /* end valid statuses */ 
                   5244:            } /* end selection of dates */
                   5245:          } /* end selection of waves */
                   5246:        } /* end bool */
                   5247:       } /* end wave */
                   5248:     } /* end individual */
                   5249:     for(i=iagemin; i <= iagemax+3; i++){  
                   5250:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5251:        posprop += prop[jk][i]; 
                   5252:       } 
                   5253:       
                   5254:       for(jk=1; jk <=nlstate ; jk++){      
                   5255:        if( i <=  iagemax){ 
                   5256:          if(posprop>=1.e-5){ 
                   5257:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5258:          } else{
1.288     brouard  5259:            if(!first){
                   5260:              first=1;
1.266     brouard  5261:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5262:            }else{
1.288     brouard  5263:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5264:            }
                   5265:          }
                   5266:        } 
                   5267:       }/* end jk */ 
                   5268:     }/* end i */ 
1.222     brouard  5269:      /*} *//* end i1 */
1.227     brouard  5270:   } /* end j1 */
1.222     brouard  5271:   
1.227     brouard  5272:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5273:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5274:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5275: }  /* End of prevalence */
1.126     brouard  5276: 
                   5277: /************* Waves Concatenation ***************/
                   5278: 
                   5279: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5280: {
1.298     brouard  5281:   /* Concatenates waves: wav[i] is the number of effective (useful waves in the sense that a non interview is useless) of individual i.
1.126     brouard  5282:      Death is a valid wave (if date is known).
                   5283:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5284:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
1.298     brouard  5285:      and mw[mi+1][i]. dh depends on stepm. s[m][i] exists for any wave from firstpass to lastpass
1.227     brouard  5286:   */
1.126     brouard  5287: 
1.224     brouard  5288:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5289:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5290:      double sum=0., jmean=0.;*/
1.224     brouard  5291:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5292:   int j, k=0,jk, ju, jl;
                   5293:   double sum=0.;
                   5294:   first=0;
1.214     brouard  5295:   firstwo=0;
1.217     brouard  5296:   firsthree=0;
1.218     brouard  5297:   firstfour=0;
1.164     brouard  5298:   jmin=100000;
1.126     brouard  5299:   jmax=-1;
                   5300:   jmean=0.;
1.224     brouard  5301: 
                   5302: /* Treating live states */
1.214     brouard  5303:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5304:     mi=0;  /* First valid wave */
1.227     brouard  5305:     mli=0; /* Last valid wave */
1.309     brouard  5306:     m=firstpass;  /* Loop on waves */
                   5307:     while(s[m][i] <= nlstate){  /* a live state or unknown state  */
1.227     brouard  5308:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5309:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5310:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
1.309     brouard  5311:        mw[++mi][i]=m; /* Valid wave: incrementing mi and updating mi; mw[mi] is the wave number of mi_th valid transition   */
1.227     brouard  5312:        mli=m;
1.224     brouard  5313:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5314:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5315:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5316:       }
1.309     brouard  5317:       else{ /* m = lastpass, eventual special issue with warning */
1.224     brouard  5318: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5319:        break;
1.224     brouard  5320: #else
1.309     brouard  5321:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){ /* case -2 (vital status unknown is warned later */
1.227     brouard  5322:          if(firsthree == 0){
1.302     brouard  5323:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5324:            firsthree=1;
                   5325:          }
1.302     brouard  5326:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.309     brouard  5327:          mw[++mi][i]=m; /* Valid transition with unknown status */
1.227     brouard  5328:          mli=m;
                   5329:        }
                   5330:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5331:          nbwarn++;
1.309     brouard  5332:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified?not a transition */
1.227     brouard  5333:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5334:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5335:          }
                   5336:          break;
                   5337:        }
                   5338:        break;
1.224     brouard  5339: #endif
1.227     brouard  5340:       }/* End m >= lastpass */
1.126     brouard  5341:     }/* end while */
1.224     brouard  5342: 
1.227     brouard  5343:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5344:     /* After last pass */
1.224     brouard  5345: /* Treating death states */
1.214     brouard  5346:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5347:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5348:       /* } */
1.126     brouard  5349:       mi++;    /* Death is another wave */
                   5350:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5351:       /* Only death is a correct wave */
1.126     brouard  5352:       mw[mi][i]=m;
1.257     brouard  5353:     } /* else not in a death state */
1.224     brouard  5354: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5355:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5356:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.309     brouard  5357:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* month of death occured before last wave month and status should have been death instead of -1 */
1.227     brouard  5358:          nbwarn++;
                   5359:          if(firstfiv==0){
1.309     brouard  5360:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5361:            firstfiv=1;
                   5362:          }else{
1.309     brouard  5363:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5364:          }
1.309     brouard  5365:            s[m][i]=nlstate+1; /* Fixing the status as death. Be careful if multiple death states */
                   5366:        }else{ /* Month of Death occured afer last wave month, potential bias */
1.227     brouard  5367:          nberr++;
                   5368:          if(firstwo==0){
1.309     brouard  5369:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5370:            firstwo=1;
                   5371:          }
1.309     brouard  5372:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5373:        }
1.257     brouard  5374:       }else{ /* if date of interview is unknown */
1.227     brouard  5375:        /* death is known but not confirmed by death status at any wave */
                   5376:        if(firstfour==0){
1.309     brouard  5377:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5378:          firstfour=1;
                   5379:        }
1.309     brouard  5380:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d  with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.214     brouard  5381:       }
1.224     brouard  5382:     } /* end if date of death is known */
                   5383: #endif
1.309     brouard  5384:     wav[i]=mi; /* mi should be the last effective wave (or mli),  */
                   5385:     /* wav[i]=mw[mi][i];   */
1.126     brouard  5386:     if(mi==0){
                   5387:       nbwarn++;
                   5388:       if(first==0){
1.227     brouard  5389:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5390:        first=1;
1.126     brouard  5391:       }
                   5392:       if(first==1){
1.227     brouard  5393:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5394:       }
                   5395:     } /* end mi==0 */
                   5396:   } /* End individuals */
1.214     brouard  5397:   /* wav and mw are no more changed */
1.223     brouard  5398:        
1.214     brouard  5399:   
1.126     brouard  5400:   for(i=1; i<=imx; i++){
                   5401:     for(mi=1; mi<wav[i];mi++){
                   5402:       if (stepm <=0)
1.227     brouard  5403:        dh[mi][i]=1;
1.126     brouard  5404:       else{
1.260     brouard  5405:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5406:          if (agedc[i] < 2*AGESUP) {
                   5407:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5408:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5409:            else if(j<0){
                   5410:              nberr++;
                   5411:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5412:              j=1; /* Temporary Dangerous patch */
                   5413:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5414:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5415:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5416:            }
                   5417:            k=k+1;
                   5418:            if (j >= jmax){
                   5419:              jmax=j;
                   5420:              ijmax=i;
                   5421:            }
                   5422:            if (j <= jmin){
                   5423:              jmin=j;
                   5424:              ijmin=i;
                   5425:            }
                   5426:            sum=sum+j;
                   5427:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5428:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5429:          }
                   5430:        }
                   5431:        else{
                   5432:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5433: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5434:                                        
1.227     brouard  5435:          k=k+1;
                   5436:          if (j >= jmax) {
                   5437:            jmax=j;
                   5438:            ijmax=i;
                   5439:          }
                   5440:          else if (j <= jmin){
                   5441:            jmin=j;
                   5442:            ijmin=i;
                   5443:          }
                   5444:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5445:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5446:          if(j<0){
                   5447:            nberr++;
                   5448:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5449:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5450:          }
                   5451:          sum=sum+j;
                   5452:        }
                   5453:        jk= j/stepm;
                   5454:        jl= j -jk*stepm;
                   5455:        ju= j -(jk+1)*stepm;
                   5456:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5457:          if(jl==0){
                   5458:            dh[mi][i]=jk;
                   5459:            bh[mi][i]=0;
                   5460:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5461:                  * to avoid the price of an extra matrix product in likelihood */
                   5462:            dh[mi][i]=jk+1;
                   5463:            bh[mi][i]=ju;
                   5464:          }
                   5465:        }else{
                   5466:          if(jl <= -ju){
                   5467:            dh[mi][i]=jk;
                   5468:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5469:                                 * is higher than the multiple of stepm and negative otherwise.
                   5470:                                 */
                   5471:          }
                   5472:          else{
                   5473:            dh[mi][i]=jk+1;
                   5474:            bh[mi][i]=ju;
                   5475:          }
                   5476:          if(dh[mi][i]==0){
                   5477:            dh[mi][i]=1; /* At least one step */
                   5478:            bh[mi][i]=ju; /* At least one step */
                   5479:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5480:          }
                   5481:        } /* end if mle */
1.126     brouard  5482:       }
                   5483:     } /* end wave */
                   5484:   }
                   5485:   jmean=sum/k;
                   5486:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5487:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5488: }
1.126     brouard  5489: 
                   5490: /*********** Tricode ****************************/
1.220     brouard  5491:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5492:  {
                   5493:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5494:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5495:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5496:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5497:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5498:     */
1.130     brouard  5499: 
1.242     brouard  5500:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5501:    int modmaxcovj=0; /* Modality max of covariates j */
                   5502:    int cptcode=0; /* Modality max of covariates j */
                   5503:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5504: 
                   5505: 
1.242     brouard  5506:    /* cptcoveff=0;  */
                   5507:    /* *cptcov=0; */
1.126     brouard  5508:  
1.242     brouard  5509:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5510:    for (k=1; k <= maxncov; k++)
                   5511:      for(j=1; j<=2; j++)
                   5512:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5513: 
1.242     brouard  5514:    /* Loop on covariates without age and products and no quantitative variable */
                   5515:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5516:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5517:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5518:        switch(Fixed[k]) {
                   5519:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
1.311     brouard  5520:         modmaxcovj=0;
                   5521:         modmincovj=0;
1.242     brouard  5522:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5523:           ij=(int)(covar[Tvar[k]][i]);
                   5524:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5525:            * If product of Vn*Vm, still boolean *:
                   5526:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5527:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5528:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5529:              modality of the nth covariate of individual i. */
                   5530:           if (ij > modmaxcovj)
                   5531:             modmaxcovj=ij; 
                   5532:           else if (ij < modmincovj) 
                   5533:             modmincovj=ij; 
1.287     brouard  5534:           if (ij <0 || ij >1 ){
1.311     brouard  5535:             printf("ERROR, IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5536:             fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5537:             fflush(ficlog);
                   5538:             exit(1);
1.287     brouard  5539:           }
                   5540:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5541:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5542:             exit(1);
                   5543:           }else
                   5544:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5545:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5546:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5547:           /* getting the maximum value of the modality of the covariate
                   5548:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5549:              female ies 1, then modmaxcovj=1.
                   5550:           */
                   5551:         } /* end for loop on individuals i */
                   5552:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5553:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5554:         cptcode=modmaxcovj;
                   5555:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5556:         /*for (i=0; i<=cptcode; i++) {*/
                   5557:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5558:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5559:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5560:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5561:             if( j != -1){
                   5562:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5563:                                  covariate for which somebody answered excluding 
                   5564:                                  undefined. Usually 2: 0 and 1. */
                   5565:             }
                   5566:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5567:                                     covariate for which somebody answered including 
                   5568:                                     undefined. Usually 3: -1, 0 and 1. */
                   5569:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5570:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5571:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5572:                        
1.242     brouard  5573:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5574:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5575:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5576:         /* modmincovj=3; modmaxcovj = 7; */
                   5577:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5578:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5579:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5580:         /* nbcode[Tvar[j]][ij]=k; */
                   5581:         /* nbcode[Tvar[j]][1]=0; */
                   5582:         /* nbcode[Tvar[j]][2]=1; */
                   5583:         /* nbcode[Tvar[j]][3]=2; */
                   5584:         /* To be continued (not working yet). */
                   5585:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5586: 
                   5587:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5588:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5589:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5590:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5591:         /*, could be restored in the future */
                   5592:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5593:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5594:             break;
                   5595:           }
                   5596:           ij++;
1.287     brouard  5597:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5598:           cptcode = ij; /* New max modality for covar j */
                   5599:         } /* end of loop on modality i=-1 to 1 or more */
                   5600:         break;
                   5601:        case 1: /* Testing on varying covariate, could be simple and
                   5602:                * should look at waves or product of fixed *
                   5603:                * varying. No time to test -1, assuming 0 and 1 only */
                   5604:         ij=0;
                   5605:         for(i=0; i<=1;i++){
                   5606:           nbcode[Tvar[k]][++ij]=i;
                   5607:         }
                   5608:         break;
                   5609:        default:
                   5610:         break;
                   5611:        } /* end switch */
                   5612:      } /* end dummy test */
1.311     brouard  5613:      if(Dummy[k]==1 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5614:        for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5615:         if(isnan(covar[Tvar[k]][i])){
                   5616:           printf("ERROR, IMaCh doesn't treat fixed quantitative covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5617:           fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5618:           fflush(ficlog);
                   5619:           exit(1);
                   5620:          }
                   5621:        }
                   5622:      }
1.287     brouard  5623:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5624:   
                   5625:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5626:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5627:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5628:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5629:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5630:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5631:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5632:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5633:   
                   5634:    ij=0;
                   5635:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5636:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5637:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5638:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5639:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5640:        /* If product not in single variable we don't print results */
                   5641:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5642:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5643:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5644:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5645:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5646:        if(Fixed[k]!=0)
                   5647:         anyvaryingduminmodel=1;
                   5648:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5649:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5650:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5651:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5652:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5653:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5654:      } 
                   5655:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5656:    /* ij--; */
                   5657:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5658:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5659:                * because they can be excluded from the model and real
                   5660:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5661:    for(j=ij+1; j<= cptcovt; j++){
                   5662:      Tvaraff[j]=0;
                   5663:      Tmodelind[j]=0;
                   5664:    }
                   5665:    for(j=ntveff+1; j<= cptcovt; j++){
                   5666:      TmodelInvind[j]=0;
                   5667:    }
                   5668:    /* To be sorted */
                   5669:    ;
                   5670:  }
1.126     brouard  5671: 
1.145     brouard  5672: 
1.126     brouard  5673: /*********** Health Expectancies ****************/
                   5674: 
1.235     brouard  5675:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5676: 
                   5677: {
                   5678:   /* Health expectancies, no variances */
1.164     brouard  5679:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5680:   int nhstepma, nstepma; /* Decreasing with age */
                   5681:   double age, agelim, hf;
                   5682:   double ***p3mat;
                   5683:   double eip;
                   5684: 
1.238     brouard  5685:   /* pstamp(ficreseij); */
1.126     brouard  5686:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5687:   fprintf(ficreseij,"# Age");
                   5688:   for(i=1; i<=nlstate;i++){
                   5689:     for(j=1; j<=nlstate;j++){
                   5690:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5691:     }
                   5692:     fprintf(ficreseij," e%1d. ",i);
                   5693:   }
                   5694:   fprintf(ficreseij,"\n");
                   5695: 
                   5696:   
                   5697:   if(estepm < stepm){
                   5698:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5699:   }
                   5700:   else  hstepm=estepm;   
                   5701:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5702:    * This is mainly to measure the difference between two models: for example
                   5703:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5704:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5705:    * progression in between and thus overestimating or underestimating according
                   5706:    * to the curvature of the survival function. If, for the same date, we 
                   5707:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5708:    * to compare the new estimate of Life expectancy with the same linear 
                   5709:    * hypothesis. A more precise result, taking into account a more precise
                   5710:    * curvature will be obtained if estepm is as small as stepm. */
                   5711: 
                   5712:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5713:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5714:      nhstepm is the number of hstepm from age to agelim 
                   5715:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5716:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5717:      and note for a fixed period like estepm months */
                   5718:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5719:      survival function given by stepm (the optimization length). Unfortunately it
                   5720:      means that if the survival funtion is printed only each two years of age and if
                   5721:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5722:      results. So we changed our mind and took the option of the best precision.
                   5723:   */
                   5724:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5725: 
                   5726:   agelim=AGESUP;
                   5727:   /* If stepm=6 months */
                   5728:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5729:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5730:     
                   5731: /* nhstepm age range expressed in number of stepm */
                   5732:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5733:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5734:   /* if (stepm >= YEARM) hstepm=1;*/
                   5735:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5736:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5737: 
                   5738:   for (age=bage; age<=fage; age ++){ 
                   5739:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5740:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5741:     /* if (stepm >= YEARM) hstepm=1;*/
                   5742:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5743: 
                   5744:     /* If stepm=6 months */
                   5745:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5746:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5747:     
1.235     brouard  5748:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5749:     
                   5750:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5751:     
                   5752:     printf("%d|",(int)age);fflush(stdout);
                   5753:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5754:     
                   5755:     /* Computing expectancies */
                   5756:     for(i=1; i<=nlstate;i++)
                   5757:       for(j=1; j<=nlstate;j++)
                   5758:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5759:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5760:          
                   5761:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5762: 
                   5763:        }
                   5764: 
                   5765:     fprintf(ficreseij,"%3.0f",age );
                   5766:     for(i=1; i<=nlstate;i++){
                   5767:       eip=0;
                   5768:       for(j=1; j<=nlstate;j++){
                   5769:        eip +=eij[i][j][(int)age];
                   5770:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5771:       }
                   5772:       fprintf(ficreseij,"%9.4f", eip );
                   5773:     }
                   5774:     fprintf(ficreseij,"\n");
                   5775:     
                   5776:   }
                   5777:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5778:   printf("\n");
                   5779:   fprintf(ficlog,"\n");
                   5780:   
                   5781: }
                   5782: 
1.235     brouard  5783:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5784: 
                   5785: {
                   5786:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5787:      to initial status i, ei. .
1.126     brouard  5788:   */
                   5789:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5790:   int nhstepma, nstepma; /* Decreasing with age */
                   5791:   double age, agelim, hf;
                   5792:   double ***p3matp, ***p3matm, ***varhe;
                   5793:   double **dnewm,**doldm;
                   5794:   double *xp, *xm;
                   5795:   double **gp, **gm;
                   5796:   double ***gradg, ***trgradg;
                   5797:   int theta;
                   5798: 
                   5799:   double eip, vip;
                   5800: 
                   5801:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5802:   xp=vector(1,npar);
                   5803:   xm=vector(1,npar);
                   5804:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5805:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5806:   
                   5807:   pstamp(ficresstdeij);
                   5808:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5809:   fprintf(ficresstdeij,"# Age");
                   5810:   for(i=1; i<=nlstate;i++){
                   5811:     for(j=1; j<=nlstate;j++)
                   5812:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5813:     fprintf(ficresstdeij," e%1d. ",i);
                   5814:   }
                   5815:   fprintf(ficresstdeij,"\n");
                   5816: 
                   5817:   pstamp(ficrescveij);
                   5818:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5819:   fprintf(ficrescveij,"# Age");
                   5820:   for(i=1; i<=nlstate;i++)
                   5821:     for(j=1; j<=nlstate;j++){
                   5822:       cptj= (j-1)*nlstate+i;
                   5823:       for(i2=1; i2<=nlstate;i2++)
                   5824:        for(j2=1; j2<=nlstate;j2++){
                   5825:          cptj2= (j2-1)*nlstate+i2;
                   5826:          if(cptj2 <= cptj)
                   5827:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5828:        }
                   5829:     }
                   5830:   fprintf(ficrescveij,"\n");
                   5831:   
                   5832:   if(estepm < stepm){
                   5833:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5834:   }
                   5835:   else  hstepm=estepm;   
                   5836:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5837:    * This is mainly to measure the difference between two models: for example
                   5838:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5839:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5840:    * progression in between and thus overestimating or underestimating according
                   5841:    * to the curvature of the survival function. If, for the same date, we 
                   5842:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5843:    * to compare the new estimate of Life expectancy with the same linear 
                   5844:    * hypothesis. A more precise result, taking into account a more precise
                   5845:    * curvature will be obtained if estepm is as small as stepm. */
                   5846: 
                   5847:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5848:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5849:      nhstepm is the number of hstepm from age to agelim 
                   5850:      nstepm is the number of stepm from age to agelin. 
                   5851:      Look at hpijx to understand the reason of that which relies in memory size
                   5852:      and note for a fixed period like estepm months */
                   5853:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5854:      survival function given by stepm (the optimization length). Unfortunately it
                   5855:      means that if the survival funtion is printed only each two years of age and if
                   5856:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5857:      results. So we changed our mind and took the option of the best precision.
                   5858:   */
                   5859:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5860: 
                   5861:   /* If stepm=6 months */
                   5862:   /* nhstepm age range expressed in number of stepm */
                   5863:   agelim=AGESUP;
                   5864:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5865:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5866:   /* if (stepm >= YEARM) hstepm=1;*/
                   5867:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5868:   
                   5869:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5870:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5871:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5872:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5873:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5874:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5875: 
                   5876:   for (age=bage; age<=fage; age ++){ 
                   5877:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5878:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5879:     /* if (stepm >= YEARM) hstepm=1;*/
                   5880:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5881:                
1.126     brouard  5882:     /* If stepm=6 months */
                   5883:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5884:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5885:     
                   5886:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5887:                
1.126     brouard  5888:     /* Computing  Variances of health expectancies */
                   5889:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5890:        decrease memory allocation */
                   5891:     for(theta=1; theta <=npar; theta++){
                   5892:       for(i=1; i<=npar; i++){ 
1.222     brouard  5893:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5894:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5895:       }
1.235     brouard  5896:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5897:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5898:                        
1.126     brouard  5899:       for(j=1; j<= nlstate; j++){
1.222     brouard  5900:        for(i=1; i<=nlstate; i++){
                   5901:          for(h=0; h<=nhstepm-1; h++){
                   5902:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5903:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5904:          }
                   5905:        }
1.126     brouard  5906:       }
1.218     brouard  5907:                        
1.126     brouard  5908:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5909:        for(h=0; h<=nhstepm-1; h++){
                   5910:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5911:        }
1.126     brouard  5912:     }/* End theta */
                   5913:     
                   5914:     
                   5915:     for(h=0; h<=nhstepm-1; h++)
                   5916:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5917:        for(theta=1; theta <=npar; theta++)
                   5918:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5919:     
1.218     brouard  5920:                
1.222     brouard  5921:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5922:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5923:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5924:                
1.222     brouard  5925:     printf("%d|",(int)age);fflush(stdout);
                   5926:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5927:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5928:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5929:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5930:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5931:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5932:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5933:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5934:       }
                   5935:     }
1.218     brouard  5936:                
1.126     brouard  5937:     /* Computing expectancies */
1.235     brouard  5938:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5939:     for(i=1; i<=nlstate;i++)
                   5940:       for(j=1; j<=nlstate;j++)
1.222     brouard  5941:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5942:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5943:                                        
1.222     brouard  5944:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5945:                                        
1.222     brouard  5946:        }
1.269     brouard  5947: 
                   5948:     /* Standard deviation of expectancies ij */                
1.126     brouard  5949:     fprintf(ficresstdeij,"%3.0f",age );
                   5950:     for(i=1; i<=nlstate;i++){
                   5951:       eip=0.;
                   5952:       vip=0.;
                   5953:       for(j=1; j<=nlstate;j++){
1.222     brouard  5954:        eip += eij[i][j][(int)age];
                   5955:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5956:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5957:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5958:       }
                   5959:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5960:     }
                   5961:     fprintf(ficresstdeij,"\n");
1.218     brouard  5962:                
1.269     brouard  5963:     /* Variance of expectancies ij */          
1.126     brouard  5964:     fprintf(ficrescveij,"%3.0f",age );
                   5965:     for(i=1; i<=nlstate;i++)
                   5966:       for(j=1; j<=nlstate;j++){
1.222     brouard  5967:        cptj= (j-1)*nlstate+i;
                   5968:        for(i2=1; i2<=nlstate;i2++)
                   5969:          for(j2=1; j2<=nlstate;j2++){
                   5970:            cptj2= (j2-1)*nlstate+i2;
                   5971:            if(cptj2 <= cptj)
                   5972:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5973:          }
1.126     brouard  5974:       }
                   5975:     fprintf(ficrescveij,"\n");
1.218     brouard  5976:                
1.126     brouard  5977:   }
                   5978:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5979:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5980:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5981:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5982:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5983:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5984:   printf("\n");
                   5985:   fprintf(ficlog,"\n");
1.218     brouard  5986:        
1.126     brouard  5987:   free_vector(xm,1,npar);
                   5988:   free_vector(xp,1,npar);
                   5989:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5990:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5991:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5992: }
1.218     brouard  5993:  
1.126     brouard  5994: /************ Variance ******************/
1.235     brouard  5995:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5996:  {
1.279     brouard  5997:    /** Variance of health expectancies 
                   5998:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5999:     * double **newm;
                   6000:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   6001:     */
1.218     brouard  6002:   
                   6003:    /* int movingaverage(); */
                   6004:    double **dnewm,**doldm;
                   6005:    double **dnewmp,**doldmp;
                   6006:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  6007:    int first=0;
1.218     brouard  6008:    int k;
                   6009:    double *xp;
1.279     brouard  6010:    double **gp, **gm;  /**< for var eij */
                   6011:    double ***gradg, ***trgradg; /**< for var eij */
                   6012:    double **gradgp, **trgradgp; /**< for var p point j */
                   6013:    double *gpp, *gmp; /**< for var p point j */
                   6014:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  6015:    double ***p3mat;
                   6016:    double age,agelim, hf;
                   6017:    /* double ***mobaverage; */
                   6018:    int theta;
                   6019:    char digit[4];
                   6020:    char digitp[25];
                   6021: 
                   6022:    char fileresprobmorprev[FILENAMELENGTH];
                   6023: 
                   6024:    if(popbased==1){
                   6025:      if(mobilav!=0)
                   6026:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   6027:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   6028:    }
                   6029:    else 
                   6030:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  6031: 
1.218     brouard  6032:    /* if (mobilav!=0) { */
                   6033:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6034:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   6035:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   6036:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   6037:    /*   } */
                   6038:    /* } */
                   6039: 
                   6040:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   6041:    sprintf(digit,"%-d",ij);
                   6042:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   6043:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   6044:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   6045:    strcat(fileresprobmorprev,fileresu);
                   6046:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   6047:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   6048:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   6049:    }
                   6050:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6051:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6052:    pstamp(ficresprobmorprev);
                   6053:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  6054:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   6055:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   6056:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   6057:    }
                   6058:    for(j=1;j<=cptcoveff;j++) 
                   6059:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   6060:    fprintf(ficresprobmorprev,"\n");
                   6061: 
1.218     brouard  6062:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   6063:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6064:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   6065:      for(i=1; i<=nlstate;i++)
                   6066:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   6067:    }  
                   6068:    fprintf(ficresprobmorprev,"\n");
                   6069:   
                   6070:    fprintf(ficgp,"\n# Routine varevsij");
                   6071:    fprintf(ficgp,"\nunset title \n");
                   6072:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   6073:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   6074:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  6075: 
1.218     brouard  6076:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6077:    pstamp(ficresvij);
                   6078:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   6079:    if(popbased==1)
                   6080:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   6081:    else
                   6082:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   6083:    fprintf(ficresvij,"# Age");
                   6084:    for(i=1; i<=nlstate;i++)
                   6085:      for(j=1; j<=nlstate;j++)
                   6086:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   6087:    fprintf(ficresvij,"\n");
                   6088: 
                   6089:    xp=vector(1,npar);
                   6090:    dnewm=matrix(1,nlstate,1,npar);
                   6091:    doldm=matrix(1,nlstate,1,nlstate);
                   6092:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   6093:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6094: 
                   6095:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   6096:    gpp=vector(nlstate+1,nlstate+ndeath);
                   6097:    gmp=vector(nlstate+1,nlstate+ndeath);
                   6098:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  6099:   
1.218     brouard  6100:    if(estepm < stepm){
                   6101:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   6102:    }
                   6103:    else  hstepm=estepm;   
                   6104:    /* For example we decided to compute the life expectancy with the smallest unit */
                   6105:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6106:       nhstepm is the number of hstepm from age to agelim 
                   6107:       nstepm is the number of stepm from age to agelim. 
                   6108:       Look at function hpijx to understand why because of memory size limitations, 
                   6109:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   6110:       survival function given by stepm (the optimization length). Unfortunately it
                   6111:       means that if the survival funtion is printed every two years of age and if
                   6112:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6113:       results. So we changed our mind and took the option of the best precision.
                   6114:    */
                   6115:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6116:    agelim = AGESUP;
                   6117:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6118:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6119:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6120:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6121:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   6122:      gp=matrix(0,nhstepm,1,nlstate);
                   6123:      gm=matrix(0,nhstepm,1,nlstate);
                   6124:                
                   6125:                
                   6126:      for(theta=1; theta <=npar; theta++){
                   6127:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   6128:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6129:        }
1.279     brouard  6130:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   6131:        * returns into prlim .
1.288     brouard  6132:        */
1.242     brouard  6133:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  6134: 
                   6135:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  6136:        if (popbased==1) {
                   6137:         if(mobilav ==0){
                   6138:           for(i=1; i<=nlstate;i++)
                   6139:             prlim[i][i]=probs[(int)age][i][ij];
                   6140:         }else{ /* mobilav */ 
                   6141:           for(i=1; i<=nlstate;i++)
                   6142:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6143:         }
                   6144:        }
1.295     brouard  6145:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}x\f$ at horizon h.
1.279     brouard  6146:        */                      
                   6147:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
1.292     brouard  6148:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}x\f$, which are the probability
1.279     brouard  6149:        * at horizon h in state j including mortality.
                   6150:        */
1.218     brouard  6151:        for(j=1; j<= nlstate; j++){
                   6152:         for(h=0; h<=nhstepm; h++){
                   6153:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6154:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6155:         }
                   6156:        }
1.279     brouard  6157:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6158:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6159:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6160:        */
                   6161:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6162:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6163:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6164:        }
                   6165:        
                   6166:        /* Again with minus shift */
1.218     brouard  6167:                        
                   6168:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6169:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6170: 
1.242     brouard  6171:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6172:                        
                   6173:        if (popbased==1) {
                   6174:         if(mobilav ==0){
                   6175:           for(i=1; i<=nlstate;i++)
                   6176:             prlim[i][i]=probs[(int)age][i][ij];
                   6177:         }else{ /* mobilav */ 
                   6178:           for(i=1; i<=nlstate;i++)
                   6179:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6180:         }
                   6181:        }
                   6182:                        
1.235     brouard  6183:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6184:                        
                   6185:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6186:         for(h=0; h<=nhstepm; h++){
                   6187:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6188:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6189:         }
                   6190:        }
                   6191:        /* This for computing probability of death (h=1 means
                   6192:          computed over hstepm matrices product = hstepm*stepm months) 
                   6193:          as a weighted average of prlim.
                   6194:        */
                   6195:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6196:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6197:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6198:        }    
1.279     brouard  6199:        /* end shifting computations */
                   6200: 
                   6201:        /**< Computing gradient matrix at horizon h 
                   6202:        */
1.218     brouard  6203:        for(j=1; j<= nlstate; j++) /* vareij */
                   6204:         for(h=0; h<=nhstepm; h++){
                   6205:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6206:         }
1.279     brouard  6207:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6208:        */
                   6209:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6210:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6211:        }
                   6212:                        
                   6213:      } /* End theta */
1.279     brouard  6214:      
                   6215:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6216:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6217:                
                   6218:      for(h=0; h<=nhstepm; h++) /* veij */
                   6219:        for(j=1; j<=nlstate;j++)
                   6220:         for(theta=1; theta <=npar; theta++)
                   6221:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6222:                
                   6223:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6224:        for(theta=1; theta <=npar; theta++)
                   6225:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6226:      /**< as well as its transposed matrix 
                   6227:       */               
1.218     brouard  6228:                
                   6229:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6230:      for(i=1;i<=nlstate;i++)
                   6231:        for(j=1;j<=nlstate;j++)
                   6232:         vareij[i][j][(int)age] =0.;
1.279     brouard  6233: 
                   6234:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6235:       * and k (nhstepm) formula 15 of article
                   6236:       * Lievre-Brouard-Heathcote
                   6237:       */
                   6238:      
1.218     brouard  6239:      for(h=0;h<=nhstepm;h++){
                   6240:        for(k=0;k<=nhstepm;k++){
                   6241:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6242:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6243:         for(i=1;i<=nlstate;i++)
                   6244:           for(j=1;j<=nlstate;j++)
                   6245:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6246:        }
                   6247:      }
                   6248:                
1.279     brouard  6249:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6250:       * p.j overall mortality formula 49 but computed directly because
                   6251:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6252:       * wix is independent of theta.
                   6253:       */
1.218     brouard  6254:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6255:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6256:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6257:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6258:         varppt[j][i]=doldmp[j][i];
                   6259:      /* end ppptj */
                   6260:      /*  x centered again */
                   6261:                
1.242     brouard  6262:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6263:                
                   6264:      if (popbased==1) {
                   6265:        if(mobilav ==0){
                   6266:         for(i=1; i<=nlstate;i++)
                   6267:           prlim[i][i]=probs[(int)age][i][ij];
                   6268:        }else{ /* mobilav */ 
                   6269:         for(i=1; i<=nlstate;i++)
                   6270:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6271:        }
                   6272:      }
                   6273:                
                   6274:      /* This for computing probability of death (h=1 means
                   6275:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6276:        as a weighted average of prlim.
                   6277:      */
1.235     brouard  6278:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6279:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6280:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6281:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6282:      }    
                   6283:      /* end probability of death */
                   6284:                
                   6285:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6286:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6287:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6288:        for(i=1; i<=nlstate;i++){
                   6289:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6290:        }
                   6291:      } 
                   6292:      fprintf(ficresprobmorprev,"\n");
                   6293:                
                   6294:      fprintf(ficresvij,"%.0f ",age );
                   6295:      for(i=1; i<=nlstate;i++)
                   6296:        for(j=1; j<=nlstate;j++){
                   6297:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6298:        }
                   6299:      fprintf(ficresvij,"\n");
                   6300:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6301:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6302:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6303:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6304:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6305:    } /* End age */
                   6306:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6307:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6308:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6309:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6310:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6311:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6312:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6313:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6314:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6315:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6316:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6317:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6318:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6319:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6320:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6321:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6322:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6323:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6324:     */
1.218     brouard  6325:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6326:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6327: 
1.218     brouard  6328:    free_vector(xp,1,npar);
                   6329:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6330:    free_matrix(dnewm,1,nlstate,1,npar);
                   6331:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6332:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6333:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6334:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6335:    fclose(ficresprobmorprev);
                   6336:    fflush(ficgp);
                   6337:    fflush(fichtm); 
                   6338:  }  /* end varevsij */
1.126     brouard  6339: 
                   6340: /************ Variance of prevlim ******************/
1.269     brouard  6341:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6342: {
1.205     brouard  6343:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6344:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6345: 
1.268     brouard  6346:   double **dnewmpar,**doldm;
1.126     brouard  6347:   int i, j, nhstepm, hstepm;
                   6348:   double *xp;
                   6349:   double *gp, *gm;
                   6350:   double **gradg, **trgradg;
1.208     brouard  6351:   double **mgm, **mgp;
1.126     brouard  6352:   double age,agelim;
                   6353:   int theta;
                   6354:   
                   6355:   pstamp(ficresvpl);
1.288     brouard  6356:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6357:   fprintf(ficresvpl,"# Age ");
                   6358:   if(nresult >=1)
                   6359:     fprintf(ficresvpl," Result# ");
1.126     brouard  6360:   for(i=1; i<=nlstate;i++)
                   6361:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6362:   fprintf(ficresvpl,"\n");
                   6363: 
                   6364:   xp=vector(1,npar);
1.268     brouard  6365:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6366:   doldm=matrix(1,nlstate,1,nlstate);
                   6367:   
                   6368:   hstepm=1*YEARM; /* Every year of age */
                   6369:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6370:   agelim = AGESUP;
                   6371:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6372:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6373:     if (stepm >= YEARM) hstepm=1;
                   6374:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6375:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6376:     mgp=matrix(1,npar,1,nlstate);
                   6377:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6378:     gp=vector(1,nlstate);
                   6379:     gm=vector(1,nlstate);
                   6380: 
                   6381:     for(theta=1; theta <=npar; theta++){
                   6382:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6383:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6384:       }
1.288     brouard  6385:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6386:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6387:       /* else */
                   6388:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6389:       for(i=1;i<=nlstate;i++){
1.126     brouard  6390:        gp[i] = prlim[i][i];
1.208     brouard  6391:        mgp[theta][i] = prlim[i][i];
                   6392:       }
1.126     brouard  6393:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6394:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6395:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6396:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6397:       /* else */
                   6398:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6399:       for(i=1;i<=nlstate;i++){
1.126     brouard  6400:        gm[i] = prlim[i][i];
1.208     brouard  6401:        mgm[theta][i] = prlim[i][i];
                   6402:       }
1.126     brouard  6403:       for(i=1;i<=nlstate;i++)
                   6404:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6405:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6406:     } /* End theta */
                   6407: 
                   6408:     trgradg =matrix(1,nlstate,1,npar);
                   6409: 
                   6410:     for(j=1; j<=nlstate;j++)
                   6411:       for(theta=1; theta <=npar; theta++)
                   6412:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6413:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6414:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6415:     /*   for(j=1; j<=nlstate;j++){ */
                   6416:     /*         printf(" %d ",j); */
                   6417:     /*         for(theta=1; theta <=npar; theta++) */
                   6418:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6419:     /*         printf("\n "); */
                   6420:     /*   } */
                   6421:     /* } */
                   6422:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6423:     /*   printf("\n gradg %d ",(int)age); */
                   6424:     /*   for(j=1; j<=nlstate;j++){ */
                   6425:     /*         printf("%d ",j); */
                   6426:     /*         for(theta=1; theta <=npar; theta++) */
                   6427:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6428:     /*         printf("\n "); */
                   6429:     /*   } */
                   6430:     /* } */
1.126     brouard  6431: 
                   6432:     for(i=1;i<=nlstate;i++)
                   6433:       varpl[i][(int)age] =0.;
1.209     brouard  6434:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6435:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6436:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6437:     }else{
1.268     brouard  6438:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6439:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6440:     }
1.126     brouard  6441:     for(i=1;i<=nlstate;i++)
                   6442:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6443: 
                   6444:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6445:     if(nresult >=1)
                   6446:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6447:     for(i=1; i<=nlstate;i++){
1.126     brouard  6448:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6449:       /* for(j=1;j<=nlstate;j++) */
                   6450:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6451:     }
1.126     brouard  6452:     fprintf(ficresvpl,"\n");
                   6453:     free_vector(gp,1,nlstate);
                   6454:     free_vector(gm,1,nlstate);
1.208     brouard  6455:     free_matrix(mgm,1,npar,1,nlstate);
                   6456:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6457:     free_matrix(gradg,1,npar,1,nlstate);
                   6458:     free_matrix(trgradg,1,nlstate,1,npar);
                   6459:   } /* End age */
                   6460: 
                   6461:   free_vector(xp,1,npar);
                   6462:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6463:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6464: 
                   6465: }
                   6466: 
                   6467: 
                   6468: /************ Variance of backprevalence limit ******************/
1.269     brouard  6469:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6470: {
                   6471:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6472:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6473: 
                   6474:   double **dnewmpar,**doldm;
                   6475:   int i, j, nhstepm, hstepm;
                   6476:   double *xp;
                   6477:   double *gp, *gm;
                   6478:   double **gradg, **trgradg;
                   6479:   double **mgm, **mgp;
                   6480:   double age,agelim;
                   6481:   int theta;
                   6482:   
                   6483:   pstamp(ficresvbl);
                   6484:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6485:   fprintf(ficresvbl,"# Age ");
                   6486:   if(nresult >=1)
                   6487:     fprintf(ficresvbl," Result# ");
                   6488:   for(i=1; i<=nlstate;i++)
                   6489:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6490:   fprintf(ficresvbl,"\n");
                   6491: 
                   6492:   xp=vector(1,npar);
                   6493:   dnewmpar=matrix(1,nlstate,1,npar);
                   6494:   doldm=matrix(1,nlstate,1,nlstate);
                   6495:   
                   6496:   hstepm=1*YEARM; /* Every year of age */
                   6497:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6498:   agelim = AGEINF;
                   6499:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6500:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6501:     if (stepm >= YEARM) hstepm=1;
                   6502:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6503:     gradg=matrix(1,npar,1,nlstate);
                   6504:     mgp=matrix(1,npar,1,nlstate);
                   6505:     mgm=matrix(1,npar,1,nlstate);
                   6506:     gp=vector(1,nlstate);
                   6507:     gm=vector(1,nlstate);
                   6508: 
                   6509:     for(theta=1; theta <=npar; theta++){
                   6510:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6511:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6512:       }
                   6513:       if(mobilavproj > 0 )
                   6514:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6515:       else
                   6516:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6517:       for(i=1;i<=nlstate;i++){
                   6518:        gp[i] = bprlim[i][i];
                   6519:        mgp[theta][i] = bprlim[i][i];
                   6520:       }
                   6521:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6522:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6523:        if(mobilavproj > 0 )
                   6524:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6525:        else
                   6526:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6527:       for(i=1;i<=nlstate;i++){
                   6528:        gm[i] = bprlim[i][i];
                   6529:        mgm[theta][i] = bprlim[i][i];
                   6530:       }
                   6531:       for(i=1;i<=nlstate;i++)
                   6532:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6533:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6534:     } /* End theta */
                   6535: 
                   6536:     trgradg =matrix(1,nlstate,1,npar);
                   6537: 
                   6538:     for(j=1; j<=nlstate;j++)
                   6539:       for(theta=1; theta <=npar; theta++)
                   6540:        trgradg[j][theta]=gradg[theta][j];
                   6541:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6542:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6543:     /*   for(j=1; j<=nlstate;j++){ */
                   6544:     /*         printf(" %d ",j); */
                   6545:     /*         for(theta=1; theta <=npar; theta++) */
                   6546:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6547:     /*         printf("\n "); */
                   6548:     /*   } */
                   6549:     /* } */
                   6550:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6551:     /*   printf("\n gradg %d ",(int)age); */
                   6552:     /*   for(j=1; j<=nlstate;j++){ */
                   6553:     /*         printf("%d ",j); */
                   6554:     /*         for(theta=1; theta <=npar; theta++) */
                   6555:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6556:     /*         printf("\n "); */
                   6557:     /*   } */
                   6558:     /* } */
                   6559: 
                   6560:     for(i=1;i<=nlstate;i++)
                   6561:       varbpl[i][(int)age] =0.;
                   6562:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6563:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6564:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6565:     }else{
                   6566:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6567:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6568:     }
                   6569:     for(i=1;i<=nlstate;i++)
                   6570:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6571: 
                   6572:     fprintf(ficresvbl,"%.0f ",age );
                   6573:     if(nresult >=1)
                   6574:       fprintf(ficresvbl,"%d ",nres );
                   6575:     for(i=1; i<=nlstate;i++)
                   6576:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6577:     fprintf(ficresvbl,"\n");
                   6578:     free_vector(gp,1,nlstate);
                   6579:     free_vector(gm,1,nlstate);
                   6580:     free_matrix(mgm,1,npar,1,nlstate);
                   6581:     free_matrix(mgp,1,npar,1,nlstate);
                   6582:     free_matrix(gradg,1,npar,1,nlstate);
                   6583:     free_matrix(trgradg,1,nlstate,1,npar);
                   6584:   } /* End age */
                   6585: 
                   6586:   free_vector(xp,1,npar);
                   6587:   free_matrix(doldm,1,nlstate,1,npar);
                   6588:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6589: 
                   6590: }
                   6591: 
                   6592: /************ Variance of one-step probabilities  ******************/
                   6593: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6594:  {
                   6595:    int i, j=0,  k1, l1, tj;
                   6596:    int k2, l2, j1,  z1;
                   6597:    int k=0, l;
                   6598:    int first=1, first1, first2;
                   6599:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6600:    double **dnewm,**doldm;
                   6601:    double *xp;
                   6602:    double *gp, *gm;
                   6603:    double **gradg, **trgradg;
                   6604:    double **mu;
                   6605:    double age, cov[NCOVMAX+1];
                   6606:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6607:    int theta;
                   6608:    char fileresprob[FILENAMELENGTH];
                   6609:    char fileresprobcov[FILENAMELENGTH];
                   6610:    char fileresprobcor[FILENAMELENGTH];
                   6611:    double ***varpij;
                   6612: 
                   6613:    strcpy(fileresprob,"PROB_"); 
                   6614:    strcat(fileresprob,fileres);
                   6615:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6616:      printf("Problem with resultfile: %s\n", fileresprob);
                   6617:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6618:    }
                   6619:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6620:    strcat(fileresprobcov,fileresu);
                   6621:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6622:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6623:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6624:    }
                   6625:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6626:    strcat(fileresprobcor,fileresu);
                   6627:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6628:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6629:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6630:    }
                   6631:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6632:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6633:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6634:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6635:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6636:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6637:    pstamp(ficresprob);
                   6638:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6639:    fprintf(ficresprob,"# Age");
                   6640:    pstamp(ficresprobcov);
                   6641:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6642:    fprintf(ficresprobcov,"# Age");
                   6643:    pstamp(ficresprobcor);
                   6644:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6645:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6646: 
                   6647: 
1.222     brouard  6648:    for(i=1; i<=nlstate;i++)
                   6649:      for(j=1; j<=(nlstate+ndeath);j++){
                   6650:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6651:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6652:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6653:      }  
                   6654:    /* fprintf(ficresprob,"\n");
                   6655:       fprintf(ficresprobcov,"\n");
                   6656:       fprintf(ficresprobcor,"\n");
                   6657:    */
                   6658:    xp=vector(1,npar);
                   6659:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6660:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6661:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6662:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6663:    first=1;
                   6664:    fprintf(ficgp,"\n# Routine varprob");
                   6665:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6666:    fprintf(fichtm,"\n");
                   6667: 
1.288     brouard  6668:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6669:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6670:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6671: and drawn. It helps understanding how is the covariance between two incidences.\
                   6672:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6673:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6674: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6675: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6676: standard deviations wide on each axis. <br>\
                   6677:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6678:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6679: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6680: 
1.222     brouard  6681:    cov[1]=1;
                   6682:    /* tj=cptcoveff; */
1.225     brouard  6683:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6684:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6685:    j1=0;
1.224     brouard  6686:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6687:      if  (cptcovn>0) {
                   6688:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6689:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6690:        fprintf(ficresprob, "**********\n#\n");
                   6691:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6692:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6693:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6694:                        
1.222     brouard  6695:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6696:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6697:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6698:                        
                   6699:                        
1.222     brouard  6700:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6701:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6702:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6703:                        
1.222     brouard  6704:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6705:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6706:        fprintf(ficresprobcor, "**********\n#");    
                   6707:        if(invalidvarcomb[j1]){
                   6708:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6709:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6710:         continue;
                   6711:        }
                   6712:      }
                   6713:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6714:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6715:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6716:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6717:      for (age=bage; age<=fage; age ++){ 
                   6718:        cov[2]=age;
                   6719:        if(nagesqr==1)
                   6720:         cov[3]= age*age;
                   6721:        for (k=1; k<=cptcovn;k++) {
                   6722:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6723:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6724:                                                                    * 1  1 1 1 1
                   6725:                                                                    * 2  2 1 1 1
                   6726:                                                                    * 3  1 2 1 1
                   6727:                                                                    */
                   6728:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6729:        }
                   6730:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6731:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6732:        for (k=1; k<=cptcovprod;k++)
                   6733:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6734:                        
                   6735:                        
1.222     brouard  6736:        for(theta=1; theta <=npar; theta++){
                   6737:         for(i=1; i<=npar; i++)
                   6738:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6739:                                
1.222     brouard  6740:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6741:                                
1.222     brouard  6742:         k=0;
                   6743:         for(i=1; i<= (nlstate); i++){
                   6744:           for(j=1; j<=(nlstate+ndeath);j++){
                   6745:             k=k+1;
                   6746:             gp[k]=pmmij[i][j];
                   6747:           }
                   6748:         }
1.220     brouard  6749:                                
1.222     brouard  6750:         for(i=1; i<=npar; i++)
                   6751:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6752:                                
1.222     brouard  6753:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6754:         k=0;
                   6755:         for(i=1; i<=(nlstate); i++){
                   6756:           for(j=1; j<=(nlstate+ndeath);j++){
                   6757:             k=k+1;
                   6758:             gm[k]=pmmij[i][j];
                   6759:           }
                   6760:         }
1.220     brouard  6761:                                
1.222     brouard  6762:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6763:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6764:        }
1.126     brouard  6765: 
1.222     brouard  6766:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6767:         for(theta=1; theta <=npar; theta++)
                   6768:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6769:                        
1.222     brouard  6770:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6771:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6772:                        
1.222     brouard  6773:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6774:                        
1.222     brouard  6775:        k=0;
                   6776:        for(i=1; i<=(nlstate); i++){
                   6777:         for(j=1; j<=(nlstate+ndeath);j++){
                   6778:           k=k+1;
                   6779:           mu[k][(int) age]=pmmij[i][j];
                   6780:         }
                   6781:        }
                   6782:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6783:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6784:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6785:                        
1.222     brouard  6786:        /*printf("\n%d ",(int)age);
                   6787:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6788:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6789:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6790:         }*/
1.220     brouard  6791:                        
1.222     brouard  6792:        fprintf(ficresprob,"\n%d ",(int)age);
                   6793:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6794:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6795:                        
1.222     brouard  6796:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6797:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6798:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6799:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6800:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6801:        }
                   6802:        i=0;
                   6803:        for (k=1; k<=(nlstate);k++){
                   6804:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6805:           i++;
                   6806:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6807:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6808:           for (j=1; j<=i;j++){
                   6809:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6810:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6811:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6812:           }
                   6813:         }
                   6814:        }/* end of loop for state */
                   6815:      } /* end of loop for age */
                   6816:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6817:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6818:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6819:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6820:     
                   6821:      /* Confidence intervalle of pij  */
                   6822:      /*
                   6823:        fprintf(ficgp,"\nunset parametric;unset label");
                   6824:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6825:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6826:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6827:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6828:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6829:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6830:      */
                   6831:                
                   6832:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6833:      first1=1;first2=2;
                   6834:      for (k2=1; k2<=(nlstate);k2++){
                   6835:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6836:         if(l2==k2) continue;
                   6837:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6838:         for (k1=1; k1<=(nlstate);k1++){
                   6839:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6840:             if(l1==k1) continue;
                   6841:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6842:             if(i<=j) continue;
                   6843:             for (age=bage; age<=fage; age ++){ 
                   6844:               if ((int)age %5==0){
                   6845:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6846:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6847:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6848:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6849:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6850:                 c12=cv12/sqrt(v1*v2);
                   6851:                 /* Computing eigen value of matrix of covariance */
                   6852:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6853:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6854:                 if ((lc2 <0) || (lc1 <0) ){
                   6855:                   if(first2==1){
                   6856:                     first1=0;
                   6857:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6858:                   }
                   6859:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6860:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6861:                   /* lc2=fabs(lc2); */
                   6862:                 }
1.220     brouard  6863:                                                                
1.222     brouard  6864:                 /* Eigen vectors */
1.280     brouard  6865:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6866:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6867:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6868:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6869:                 }else
                   6870:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6871:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6872:                 v21=(lc1-v1)/cv12*v11;
                   6873:                 v12=-v21;
                   6874:                 v22=v11;
                   6875:                 tnalp=v21/v11;
                   6876:                 if(first1==1){
                   6877:                   first1=0;
                   6878:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6879:                 }
                   6880:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6881:                 /*printf(fignu*/
                   6882:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6883:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6884:                 if(first==1){
                   6885:                   first=0;
                   6886:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6887:                   fprintf(ficgp,"\nset parametric;unset label");
                   6888:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6889:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6890:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6891:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6892: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6893:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6894:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6895:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6896:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6897:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6898:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6899:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6900:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6901:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6902:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6903:                 }else{
                   6904:                   first=0;
                   6905:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6906:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6907:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6908:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6909:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6910:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6911:                 }/* if first */
                   6912:               } /* age mod 5 */
                   6913:             } /* end loop age */
                   6914:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6915:             first=1;
                   6916:           } /*l12 */
                   6917:         } /* k12 */
                   6918:        } /*l1 */
                   6919:      }/* k1 */
                   6920:    }  /* loop on combination of covariates j1 */
                   6921:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6922:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6923:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6924:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6925:    free_vector(xp,1,npar);
                   6926:    fclose(ficresprob);
                   6927:    fclose(ficresprobcov);
                   6928:    fclose(ficresprobcor);
                   6929:    fflush(ficgp);
                   6930:    fflush(fichtmcov);
                   6931:  }
1.126     brouard  6932: 
                   6933: 
                   6934: /******************* Printing html file ***********/
1.201     brouard  6935: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6936:                  int lastpass, int stepm, int weightopt, char model[],\
                   6937:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.296     brouard  6938:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int prevbcast, int estepm , \
                   6939:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateprojd, double dateback1, \
                   6940:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateprojf, double dateback2){
1.237     brouard  6941:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6942: 
                   6943:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6944:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6945: </ul>");
1.237     brouard  6946:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6947: </ul>", model);
1.214     brouard  6948:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6949:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6950:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6951:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6952:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6953:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6954:    fprintf(fichtm,"\
                   6955:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6956:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6957:    fprintf(fichtm,"\
1.217     brouard  6958:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6959:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6960:    fprintf(fichtm,"\
1.288     brouard  6961:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6962:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6963:    fprintf(fichtm,"\
1.288     brouard  6964:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  6965:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6966:    fprintf(fichtm,"\
1.211     brouard  6967:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6968:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6969:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6970:    if(prevfcast==1){
                   6971:      fprintf(fichtm,"\
                   6972:  - Prevalence projections by age and states:                           \
1.201     brouard  6973:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6974:    }
1.126     brouard  6975: 
                   6976: 
1.225     brouard  6977:    m=pow(2,cptcoveff);
1.222     brouard  6978:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6979: 
1.264     brouard  6980:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6981: 
                   6982:    jj1=0;
                   6983: 
                   6984:    fprintf(fichtm," \n<ul>");
                   6985:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6986:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6987:      if(m != 1 && TKresult[nres]!= k1)
                   6988:        continue;
                   6989:      jj1++;
                   6990:      if (cptcovn > 0) {
                   6991:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6992:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6993:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6994:        }
                   6995:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6996:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6997:        }
                   6998:        fprintf(fichtm,"\">");
                   6999:        
                   7000:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   7001:        fprintf(fichtm,"************ Results for covariates");
                   7002:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7003:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7004:        }
                   7005:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7006:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7007:        }
                   7008:        if(invalidvarcomb[k1]){
                   7009:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   7010:         continue;
                   7011:        }
                   7012:        fprintf(fichtm,"</a></li>");
                   7013:      } /* cptcovn >0 */
                   7014:    }
                   7015:      fprintf(fichtm," \n</ul>");
                   7016: 
1.222     brouard  7017:    jj1=0;
1.237     brouard  7018: 
                   7019:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  7020:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  7021:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7022:        continue;
1.220     brouard  7023: 
1.222     brouard  7024:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7025:      jj1++;
                   7026:      if (cptcovn > 0) {
1.264     brouard  7027:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   7028:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7029:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7030:        }
                   7031:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7032:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7033:        }
                   7034:        fprintf(fichtm,"\"</a>");
                   7035:  
1.222     brouard  7036:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7037:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  7038:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7039:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   7040:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7041:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  7042:        }
1.237     brouard  7043:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7044:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7045:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   7046:       }
                   7047:        
1.230     brouard  7048:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  7049:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   7050:        if(invalidvarcomb[k1]){
                   7051:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   7052:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   7053:         continue;
                   7054:        }
                   7055:      }
                   7056:      /* aij, bij */
1.259     brouard  7057:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  7058: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  7059:      /* Pij */
1.241     brouard  7060:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   7061: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  7062:      /* Quasi-incidences */
                   7063:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  7064:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  7065:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  7066: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   7067: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  7068:      /* Survival functions (period) in state j */
                   7069:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7070:        fprintf(fichtm,"<br>\n- Survival functions in state %d. And probability to be observed in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7071: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  7072:      }
                   7073:      /* State specific survival functions (period) */
                   7074:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7075:        fprintf(fichtm,"<br>\n- Survival functions in state %d and in any other live state (total).\
                   7076:  And probability to be observed in various states (up to %d) being in state %d at different ages.      \
1.283     brouard  7077:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  7078:      }
1.288     brouard  7079:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  7080:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7081:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7082: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  7083:      }
1.296     brouard  7084:      if(prevbcast==1){
1.288     brouard  7085:        /* Backward prevalence in each health state */
1.222     brouard  7086:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7087:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7088: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  7089:        }
1.217     brouard  7090:      }
1.222     brouard  7091:      if(prevfcast==1){
1.288     brouard  7092:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  7093:        for(cpt=1; cpt<=nlstate;cpt++){
1.314   ! brouard  7094:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>", dateprev1, dateprev2, mobilavproj, dateprojd, dateprojf, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
        !          7095:         fprintf(fichtm," (data from text file  <a href=\"%s.txt\">%s.txt</a>)\n<br>",subdirf2(optionfilefiname,"F_"),subdirf2(optionfilefiname,"F_"));
        !          7096:         fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">",
        !          7097:                 subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  7098:        }
                   7099:      }
1.296     brouard  7100:      if(prevbcast==1){
1.268     brouard  7101:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   7102:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  7103:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   7104:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   7105:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
1.314   ! brouard  7106: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
        !          7107:         fprintf(fichtm," (data from text file  <a href=\"%s.txt\">%s.txt</a>)\n<br>",subdirf2(optionfilefiname,"FB_"),subdirf2(optionfilefiname,"FB_"));
        !          7108:         fprintf(fichtm," <img src=\"%s_%d-%d-%d.svg\">", subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  7109:        }
                   7110:      }
1.220     brouard  7111:         
1.222     brouard  7112:      for(cpt=1; cpt<=nlstate;cpt++) {
1.314   ! brouard  7113:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
        !          7114:        fprintf(fichtm," (data from text file  <a href=\"%s.txt\"> %s.txt</a>)\n<br>",subdirf2(optionfilefiname,"E_"),subdirf2(optionfilefiname,"E_"));
        !          7115:        fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">", subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres );
1.222     brouard  7116:      }
                   7117:      /* } /\* end i1 *\/ */
                   7118:    }/* End k1 */
                   7119:    fprintf(fichtm,"</ul>");
1.126     brouard  7120: 
1.222     brouard  7121:    fprintf(fichtm,"\
1.126     brouard  7122: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  7123:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  7124:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  7125: But because parameters are usually highly correlated (a higher incidence of disability \
                   7126: and a higher incidence of recovery can give very close observed transition) it might \
                   7127: be very useful to look not only at linear confidence intervals estimated from the \
                   7128: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   7129: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   7130: covariance matrix of the one-step probabilities. \
                   7131: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  7132: 
1.222     brouard  7133:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   7134:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   7135:    fprintf(fichtm,"\
1.126     brouard  7136:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7137:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  7138: 
1.222     brouard  7139:    fprintf(fichtm,"\
1.126     brouard  7140:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7141:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   7142:    fprintf(fichtm,"\
1.126     brouard  7143:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7144:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7145:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7146:    fprintf(fichtm,"\
1.126     brouard  7147:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7148:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7149:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7150:    fprintf(fichtm,"\
1.288     brouard  7151:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7152:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7153:    fprintf(fichtm,"\
1.128     brouard  7154:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7155:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7156:    fprintf(fichtm,"\
1.288     brouard  7157:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7158:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7159: 
                   7160: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7161: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7162: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7163: /*     <br>",fileres,fileres,fileres,fileres); */
                   7164: /*  else  */
                   7165: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7166:    fflush(fichtm);
                   7167:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  7168: 
1.225     brouard  7169:    m=pow(2,cptcoveff);
1.222     brouard  7170:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7171: 
1.222     brouard  7172:    jj1=0;
1.237     brouard  7173: 
1.241     brouard  7174:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7175:    for(k1=1; k1<=m;k1++){
1.253     brouard  7176:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7177:        continue;
1.222     brouard  7178:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7179:      jj1++;
1.126     brouard  7180:      if (cptcovn > 0) {
                   7181:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7182:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7183:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7184:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7185:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7186:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7187:       }
                   7188: 
1.126     brouard  7189:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7190: 
1.222     brouard  7191:        if(invalidvarcomb[k1]){
                   7192:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7193:         continue;
                   7194:        }
1.126     brouard  7195:      }
                   7196:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7197:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.314   ! brouard  7198: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
        !          7199:        fprintf(fichtm," (data from text file  <a href=\"%s\">%s</a>)\n <br>",subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
        !          7200:        fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">",subdirf2(optionfilefiname,"V_"), cpt,k1,nres);
1.126     brouard  7201:      }
                   7202:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.314   ! brouard  7203: health expectancies in each live states (1 to %d). If popbased=1 the smooth (due to the model) \
1.128     brouard  7204: true period expectancies (those weighted with period prevalences are also\
                   7205:  drawn in addition to the population based expectancies computed using\
1.314   ! brouard  7206:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>",nlstate, subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
        !          7207:      fprintf(fichtm," (data from text file <a href=\"%s.txt\">%s.txt</a>) \n<br>",subdirf2(optionfilefiname,"T_"),subdirf2(optionfilefiname,"T_"));
        !          7208:      fprintf(fichtm,"<img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7209:      /* } /\* end i1 *\/ */
                   7210:    }/* End k1 */
1.241     brouard  7211:   }/* End nres */
1.222     brouard  7212:    fprintf(fichtm,"</ul>");
                   7213:    fflush(fichtm);
1.126     brouard  7214: }
                   7215: 
                   7216: /******************* Gnuplot file **************/
1.296     brouard  7217: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int prevbcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7218: 
                   7219:   char dirfileres[132],optfileres[132];
1.264     brouard  7220:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7221:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7222:   int lv=0, vlv=0, kl=0;
1.130     brouard  7223:   int ng=0;
1.201     brouard  7224:   int vpopbased;
1.223     brouard  7225:   int ioffset; /* variable offset for columns */
1.270     brouard  7226:   int iyearc=1; /* variable column for year of projection  */
                   7227:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7228:   int nres=0; /* Index of resultline */
1.266     brouard  7229:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7230: 
1.126     brouard  7231: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7232: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7233: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7234: /*   } */
                   7235: 
                   7236:   /*#ifdef windows */
                   7237:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7238:   /*#endif */
1.225     brouard  7239:   m=pow(2,cptcoveff);
1.126     brouard  7240: 
1.274     brouard  7241:   /* diagram of the model */
                   7242:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7243:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7244:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7245:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7246: 
                   7247:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7248:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7249:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7250:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7251:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7252:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7253:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7254: 
1.202     brouard  7255:   /* Contribution to likelihood */
                   7256:   /* Plot the probability implied in the likelihood */
1.223     brouard  7257:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7258:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7259:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7260:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7261: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7262:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7263: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7264:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7265:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7266:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7267:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7268:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7269:   for (i=1; i<= nlstate ; i ++) {
                   7270:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7271:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7272:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7273:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7274:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7275:     }
                   7276:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7277:   }
                   7278:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7279:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7280:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7281:   fprintf(ficgp,"\nset out;unset log\n");
                   7282:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7283: 
1.126     brouard  7284:   strcpy(dirfileres,optionfilefiname);
                   7285:   strcpy(optfileres,"vpl");
1.223     brouard  7286:   /* 1eme*/
1.238     brouard  7287:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7288:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7289:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7290:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7291:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7292:          continue;
                   7293:        /* We are interested in selected combination by the resultline */
1.246     brouard  7294:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7295:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7296:        strcpy(gplotlabel,"(");
1.238     brouard  7297:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7298:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7299:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7300:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7301:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7302:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7303:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7304:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7305:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7306:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7307:        }
                   7308:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7309:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7310:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7311:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7312:        }
                   7313:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7314:        /* printf("\n#\n"); */
1.238     brouard  7315:        fprintf(ficgp,"\n#\n");
                   7316:        if(invalidvarcomb[k1]){
1.260     brouard  7317:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7318:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7319:          continue;
                   7320:        }
1.235     brouard  7321:       
1.241     brouard  7322:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7323:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7324:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7325:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7326:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7327:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7328:       /* k1-1 error should be nres-1*/
1.238     brouard  7329:        for (i=1; i<= nlstate ; i ++) {
                   7330:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7331:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7332:        }
1.288     brouard  7333:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7334:        for (i=1; i<= nlstate ; i ++) {
                   7335:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7336:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7337:        } 
1.260     brouard  7338:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7339:        for (i=1; i<= nlstate ; i ++) {
                   7340:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7341:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7342:        }  
1.265     brouard  7343:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7344:        
                   7345:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7346:         if(cptcoveff ==0){
1.271     brouard  7347:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7348:        }else{
                   7349:          kl=0;
                   7350:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7351:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7352:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7353:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7354:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7355:            vlv= nbcode[Tvaraff[k]][lv];
                   7356:            kl++;
                   7357:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7358:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7359:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7360:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7361:            if(k==cptcoveff){
                   7362:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7363:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7364:            }else{
                   7365:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7366:              kl++;
                   7367:            }
                   7368:          } /* end covariate */
                   7369:        } /* end if no covariate */
                   7370: 
1.296     brouard  7371:        if(prevbcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
1.238     brouard  7372:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7373:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7374:          if(cptcoveff ==0){
1.245     brouard  7375:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7376:          }else{
                   7377:            kl=0;
                   7378:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7379:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7380:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7381:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7382:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7383:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7384:              kl++;
1.238     brouard  7385:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7386:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7387:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7388:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7389:              if(k==cptcoveff){
1.245     brouard  7390:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7391:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7392:              }else{
                   7393:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7394:                kl++;
                   7395:              }
                   7396:            } /* end covariate */
                   7397:          } /* end if no covariate */
1.296     brouard  7398:          if(prevbcast == 1){
1.268     brouard  7399:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7400:            /* k1-1 error should be nres-1*/
                   7401:            for (i=1; i<= nlstate ; i ++) {
                   7402:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7403:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7404:            }
1.271     brouard  7405:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7406:            for (i=1; i<= nlstate ; i ++) {
                   7407:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7408:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7409:            } 
1.276     brouard  7410:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7411:            for (i=1; i<= nlstate ; i ++) {
                   7412:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7413:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7414:            } 
1.274     brouard  7415:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7416:          } /* end if backprojcast */
1.296     brouard  7417:        } /* end if prevbcast */
1.276     brouard  7418:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7419:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7420:       } /* nres */
1.201     brouard  7421:     } /* k1 */
                   7422:   } /* cpt */
1.235     brouard  7423: 
                   7424:   
1.126     brouard  7425:   /*2 eme*/
1.238     brouard  7426:   for (k1=1; k1<= m ; k1 ++){  
                   7427:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7428:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7429:        continue;
                   7430:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7431:       strcpy(gplotlabel,"(");
1.238     brouard  7432:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7433:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7434:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7435:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7436:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7437:        vlv= nbcode[Tvaraff[k]][lv];
                   7438:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7439:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7440:       }
1.237     brouard  7441:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7442:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7443:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7444:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7445:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7446:       }
1.264     brouard  7447:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7448:       fprintf(ficgp,"\n#\n");
1.223     brouard  7449:       if(invalidvarcomb[k1]){
                   7450:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7451:        continue;
                   7452:       }
1.219     brouard  7453:                        
1.241     brouard  7454:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7455:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7456:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7457:        if(vpopbased==0){
1.238     brouard  7458:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7459:        }else
1.238     brouard  7460:          fprintf(ficgp,"\nreplot ");
                   7461:        for (i=1; i<= nlstate+1 ; i ++) {
                   7462:          k=2*i;
1.261     brouard  7463:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7464:          for (j=1; j<= nlstate+1 ; j ++) {
                   7465:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7466:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7467:          }   
                   7468:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7469:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7470:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7471:          for (j=1; j<= nlstate+1 ; j ++) {
                   7472:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7473:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7474:          }   
                   7475:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7476:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7477:          for (j=1; j<= nlstate+1 ; j ++) {
                   7478:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7479:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7480:          }   
                   7481:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7482:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7483:        } /* state */
                   7484:       } /* vpopbased */
1.264     brouard  7485:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7486:     } /* end nres */
                   7487:   } /* k1 end 2 eme*/
                   7488:        
                   7489:        
                   7490:   /*3eme*/
                   7491:   for (k1=1; k1<= m ; k1 ++){
                   7492:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7493:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7494:        continue;
                   7495: 
                   7496:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7497:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7498:        strcpy(gplotlabel,"(");
1.238     brouard  7499:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7500:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7501:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7502:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7503:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7504:          vlv= nbcode[Tvaraff[k]][lv];
                   7505:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7506:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7507:        }
                   7508:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7509:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7510:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7511:        }       
1.264     brouard  7512:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7513:        fprintf(ficgp,"\n#\n");
                   7514:        if(invalidvarcomb[k1]){
                   7515:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7516:          continue;
                   7517:        }
                   7518:                        
                   7519:        /*       k=2+nlstate*(2*cpt-2); */
                   7520:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7521:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7522:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7523:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7524: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7525:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7526:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7527:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7528:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7529:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7530:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7531:                                
1.238     brouard  7532:        */
                   7533:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7534:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7535:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7536:                                
1.238     brouard  7537:        } 
1.261     brouard  7538:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7539:       }
1.264     brouard  7540:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7541:     } /* end nres */
                   7542:   } /* end kl 3eme */
1.126     brouard  7543:   
1.223     brouard  7544:   /* 4eme */
1.201     brouard  7545:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7546:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7547:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7548:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7549:        continue;
1.238     brouard  7550:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7551:        strcpy(gplotlabel,"(");
1.238     brouard  7552:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7553:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7554:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7555:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7556:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7557:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7558:          vlv= nbcode[Tvaraff[k]][lv];
                   7559:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7560:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7561:        }
                   7562:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7563:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7564:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7565:        }       
1.264     brouard  7566:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7567:        fprintf(ficgp,"\n#\n");
                   7568:        if(invalidvarcomb[k1]){
                   7569:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7570:          continue;
1.223     brouard  7571:        }
1.238     brouard  7572:       
1.241     brouard  7573:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7574:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7575:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7576: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7577:        k=3;
                   7578:        for (i=1; i<= nlstate ; i ++){
                   7579:          if(i==1){
                   7580:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7581:          }else{
                   7582:            fprintf(ficgp,", '' ");
                   7583:          }
                   7584:          l=(nlstate+ndeath)*(i-1)+1;
                   7585:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7586:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7587:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7588:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7589:        } /* nlstate */
1.264     brouard  7590:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7591:       } /* end cpt state*/ 
                   7592:     } /* end nres */
                   7593:   } /* end covariate k1 */  
                   7594: 
1.220     brouard  7595: /* 5eme */
1.201     brouard  7596:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7597:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7598:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7599:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7600:        continue;
1.238     brouard  7601:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7602:        strcpy(gplotlabel,"(");
1.238     brouard  7603:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7604:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7605:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7606:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7607:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7608:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7609:          vlv= nbcode[Tvaraff[k]][lv];
                   7610:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7611:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7612:        }
                   7613:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7614:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7615:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7616:        }       
1.264     brouard  7617:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7618:        fprintf(ficgp,"\n#\n");
                   7619:        if(invalidvarcomb[k1]){
                   7620:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7621:          continue;
                   7622:        }
1.227     brouard  7623:       
1.241     brouard  7624:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7625:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7626:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7627: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7628:        k=3;
                   7629:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7630:          if(j==1)
                   7631:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7632:          else
                   7633:            fprintf(ficgp,", '' ");
                   7634:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7635:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7636:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7637:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7638:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7639:        } /* nlstate */
                   7640:        fprintf(ficgp,", '' ");
                   7641:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7642:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7643:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7644:          if(j < nlstate)
                   7645:            fprintf(ficgp,"$%d +",k+l);
                   7646:          else
                   7647:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7648:        }
1.264     brouard  7649:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7650:       } /* end cpt state*/ 
                   7651:     } /* end covariate */  
                   7652:   } /* end nres */
1.227     brouard  7653:   
1.220     brouard  7654: /* 6eme */
1.202     brouard  7655:   /* CV preval stable (period) for each covariate */
1.237     brouard  7656:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7657:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7658:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7659:       continue;
1.255     brouard  7660:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7661:       strcpy(gplotlabel,"(");      
1.288     brouard  7662:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7663:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7664:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7665:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7666:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7667:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7668:        vlv= nbcode[Tvaraff[k]][lv];
                   7669:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7670:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7671:       }
1.237     brouard  7672:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7673:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7674:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7675:       }        
1.264     brouard  7676:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7677:       fprintf(ficgp,"\n#\n");
1.223     brouard  7678:       if(invalidvarcomb[k1]){
1.227     brouard  7679:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7680:        continue;
1.223     brouard  7681:       }
1.227     brouard  7682:       
1.241     brouard  7683:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7684:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7685:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7686: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7687:       k=3; /* Offset */
1.255     brouard  7688:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7689:        if(i==1)
                   7690:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7691:        else
                   7692:          fprintf(ficgp,", '' ");
1.255     brouard  7693:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7694:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7695:        for (j=2; j<= nlstate ; j ++)
                   7696:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7697:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7698:       } /* nlstate */
1.264     brouard  7699:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7700:     } /* end cpt state*/ 
                   7701:   } /* end covariate */  
1.227     brouard  7702:   
                   7703:   
1.220     brouard  7704: /* 7eme */
1.296     brouard  7705:   if(prevbcast == 1){
1.288     brouard  7706:     /* CV backward prevalence  for each covariate */
1.237     brouard  7707:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7708:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7709:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7710:        continue;
1.268     brouard  7711:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7712:        strcpy(gplotlabel,"(");      
1.288     brouard  7713:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7714:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7715:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7716:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7717:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7718:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7719:          vlv= nbcode[Tvaraff[k]][lv];
                   7720:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7721:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7722:        }
1.237     brouard  7723:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7724:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7725:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7726:        }       
1.264     brouard  7727:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7728:        fprintf(ficgp,"\n#\n");
                   7729:        if(invalidvarcomb[k1]){
                   7730:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7731:          continue;
                   7732:        }
                   7733:        
1.241     brouard  7734:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7735:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7736:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7737: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7738:        k=3; /* Offset */
1.268     brouard  7739:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7740:          if(i==1)
                   7741:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7742:          else
                   7743:            fprintf(ficgp,", '' ");
                   7744:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7745:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7746:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7747:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7748:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7749:          /* for (j=2; j<= nlstate ; j ++) */
                   7750:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7751:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7752:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7753:        } /* nlstate */
1.264     brouard  7754:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7755:       } /* end cpt state*/ 
                   7756:     } /* end covariate */  
1.296     brouard  7757:   } /* End if prevbcast */
1.218     brouard  7758:   
1.223     brouard  7759:   /* 8eme */
1.218     brouard  7760:   if(prevfcast==1){
1.288     brouard  7761:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  7762:     
1.237     brouard  7763:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7764:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7765:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7766:        continue;
1.211     brouard  7767:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7768:        strcpy(gplotlabel,"(");      
1.288     brouard  7769:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7770:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7771:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7772:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7773:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7774:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7775:          vlv= nbcode[Tvaraff[k]][lv];
                   7776:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7777:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7778:        }
1.237     brouard  7779:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7780:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7781:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7782:        }       
1.264     brouard  7783:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7784:        fprintf(ficgp,"\n#\n");
                   7785:        if(invalidvarcomb[k1]){
                   7786:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7787:          continue;
                   7788:        }
                   7789:        
                   7790:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7791:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7792:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7793:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7794: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7795: 
                   7796:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7797:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7798:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7799:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7800:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7801:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7802:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7803:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7804:          if(i==istart){
1.227     brouard  7805:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7806:          }else{
                   7807:            fprintf(ficgp,",\\\n '' ");
                   7808:          }
                   7809:          if(cptcoveff ==0){ /* No covariate */
                   7810:            ioffset=2; /* Age is in 2 */
                   7811:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7812:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7813:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7814:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7815:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7816:            if(i==nlstate+1){
1.270     brouard  7817:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7818:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7819:              fprintf(ficgp,",\\\n '' ");
                   7820:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7821:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7822:                     offyear,                           \
1.268     brouard  7823:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7824:            }else
1.227     brouard  7825:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7826:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7827:          }else{ /* more than 2 covariates */
1.270     brouard  7828:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7829:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7830:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7831:            iyearc=ioffset-1;
                   7832:            iagec=ioffset;
1.227     brouard  7833:            fprintf(ficgp," u %d:(",ioffset); 
                   7834:            kl=0;
                   7835:            strcpy(gplotcondition,"(");
                   7836:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7837:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7838:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7839:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7840:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7841:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7842:              kl++;
                   7843:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7844:              kl++;
                   7845:              if(k <cptcoveff && cptcoveff>1)
                   7846:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7847:            }
                   7848:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7849:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7850:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7851:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7852:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7853:            if(i==nlstate+1){
1.270     brouard  7854:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7855:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7856:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7857:              fprintf(ficgp," u %d:(",iagec); 
                   7858:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7859:                      iyearc, iagec, offyear,                           \
                   7860:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7861: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7862:            }else{
                   7863:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7864:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7865:            }
                   7866:          } /* end if covariate */
                   7867:        } /* nlstate */
1.264     brouard  7868:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7869:       } /* end cpt state*/
                   7870:     } /* end covariate */
                   7871:   } /* End if prevfcast */
1.227     brouard  7872:   
1.296     brouard  7873:   if(prevbcast==1){
1.268     brouard  7874:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7875:     
                   7876:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7877:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7878:       if(m != 1 && TKresult[nres]!= k1)
                   7879:        continue;
                   7880:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7881:        strcpy(gplotlabel,"(");      
                   7882:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7883:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7884:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7885:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7886:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7887:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7888:          vlv= nbcode[Tvaraff[k]][lv];
                   7889:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7890:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7891:        }
                   7892:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7893:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7894:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7895:        }       
                   7896:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7897:        fprintf(ficgp,"\n#\n");
                   7898:        if(invalidvarcomb[k1]){
                   7899:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7900:          continue;
                   7901:        }
                   7902:        
                   7903:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7904:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7905:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7906:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7907: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7908: 
                   7909:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7910:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7911:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7912:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7913:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7914:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7915:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7916:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7917:          if(i==istart){
                   7918:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7919:          }else{
                   7920:            fprintf(ficgp,",\\\n '' ");
                   7921:          }
                   7922:          if(cptcoveff ==0){ /* No covariate */
                   7923:            ioffset=2; /* Age is in 2 */
                   7924:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7925:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7926:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7927:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7928:            fprintf(ficgp," u %d:(", ioffset); 
                   7929:            if(i==nlstate+1){
1.270     brouard  7930:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7931:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7932:              fprintf(ficgp,",\\\n '' ");
                   7933:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7934:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7935:                     offbyear,                          \
                   7936:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7937:            }else
                   7938:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7939:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7940:          }else{ /* more than 2 covariates */
1.270     brouard  7941:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7942:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7943:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7944:            iyearc=ioffset-1;
                   7945:            iagec=ioffset;
1.268     brouard  7946:            fprintf(ficgp," u %d:(",ioffset); 
                   7947:            kl=0;
                   7948:            strcpy(gplotcondition,"(");
                   7949:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7950:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7951:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7952:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7953:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7954:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7955:              kl++;
                   7956:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7957:              kl++;
                   7958:              if(k <cptcoveff && cptcoveff>1)
                   7959:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7960:            }
                   7961:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7962:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7963:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7964:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7965:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7966:            if(i==nlstate+1){
1.270     brouard  7967:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7968:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7969:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7970:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7971:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7972:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7973:                      iyearc,iagec,offbyear,                            \
                   7974:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7975: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7976:            }else{
                   7977:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7978:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7979:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7980:            }
                   7981:          } /* end if covariate */
                   7982:        } /* nlstate */
                   7983:        fprintf(ficgp,"\nset out; unset label;\n");
                   7984:       } /* end cpt state*/
                   7985:     } /* end covariate */
1.296     brouard  7986:   } /* End if prevbcast */
1.268     brouard  7987:   
1.227     brouard  7988:   
1.238     brouard  7989:   /* 9eme writing MLE parameters */
                   7990:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7991:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7992:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7993:     for(k=1; k <=(nlstate+ndeath); k++){
                   7994:       if (k != i) {
1.227     brouard  7995:        fprintf(ficgp,"#   current state %d\n",k);
                   7996:        for(j=1; j <=ncovmodel; j++){
                   7997:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7998:          jk++; 
                   7999:        }
                   8000:        fprintf(ficgp,"\n");
1.126     brouard  8001:       }
                   8002:     }
1.223     brouard  8003:   }
1.187     brouard  8004:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  8005:   
1.145     brouard  8006:   /*goto avoid;*/
1.238     brouard  8007:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   8008:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  8009:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   8010:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   8011:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   8012:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   8013:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8014:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8015:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8016:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8017:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   8018:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8019:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   8020:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   8021:   fprintf(ficgp,"#\n");
1.223     brouard  8022:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  8023:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  8024:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  8025:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  8026:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   8027:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  8028:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  8029:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  8030:        continue;
1.264     brouard  8031:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   8032:       strcpy(gplotlabel,"(");
1.276     brouard  8033:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  8034:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8035:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8036:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8037:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8038:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8039:        vlv= nbcode[Tvaraff[k]][lv];
                   8040:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   8041:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   8042:       }
1.237     brouard  8043:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8044:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  8045:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  8046:       }        
1.264     brouard  8047:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  8048:       fprintf(ficgp,"\n#\n");
1.264     brouard  8049:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  8050:       fprintf(ficgp,"\nset key outside ");
                   8051:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   8052:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  8053:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   8054:       if (ng==1){
                   8055:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   8056:        fprintf(ficgp,"\nunset log y");
                   8057:       }else if (ng==2){
                   8058:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   8059:        fprintf(ficgp,"\nset log y");
                   8060:       }else if (ng==3){
                   8061:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   8062:        fprintf(ficgp,"\nset log y");
                   8063:       }else
                   8064:        fprintf(ficgp,"\nunset title ");
                   8065:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   8066:       i=1;
                   8067:       for(k2=1; k2<=nlstate; k2++) {
                   8068:        k3=i;
                   8069:        for(k=1; k<=(nlstate+ndeath); k++) {
                   8070:          if (k != k2){
                   8071:            switch( ng) {
                   8072:            case 1:
                   8073:              if(nagesqr==0)
                   8074:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   8075:              else /* nagesqr =1 */
                   8076:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8077:              break;
                   8078:            case 2: /* ng=2 */
                   8079:              if(nagesqr==0)
                   8080:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   8081:              else /* nagesqr =1 */
                   8082:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8083:              break;
                   8084:            case 3:
                   8085:              if(nagesqr==0)
                   8086:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   8087:              else /* nagesqr =1 */
                   8088:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   8089:              break;
                   8090:            }
                   8091:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  8092:            ijp=1; /* product no age */
                   8093:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   8094:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  8095:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  8096:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8097:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   8098:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8099:                    if(DummyV[j]==0){
                   8100:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   8101:                    }else{ /* quantitative */
                   8102:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   8103:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8104:                    }
                   8105:                    ij++;
1.237     brouard  8106:                  }
1.268     brouard  8107:                } 
                   8108:              }else if(cptcovprod >0){
                   8109:                if(j==Tprod[ijp]) { /* */ 
                   8110:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   8111:                  if(ijp <=cptcovprod) { /* Product */
                   8112:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   8113:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   8114:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   8115:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   8116:                      }else{ /* Vn is dummy and Vm is quanti */
                   8117:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   8118:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8119:                      }
                   8120:                    }else{ /* Vn*Vm Vn is quanti */
                   8121:                      if(DummyV[Tvard[ijp][2]]==0){
                   8122:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   8123:                      }else{ /* Both quanti */
                   8124:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8125:                      }
1.237     brouard  8126:                    }
1.268     brouard  8127:                    ijp++;
1.237     brouard  8128:                  }
1.268     brouard  8129:                } /* end Tprod */
1.237     brouard  8130:              } else{  /* simple covariate */
1.264     brouard  8131:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  8132:                if(Dummy[j]==0){
                   8133:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   8134:                }else{ /* quantitative */
                   8135:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  8136:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  8137:                }
1.237     brouard  8138:              } /* end simple */
                   8139:            } /* end j */
1.223     brouard  8140:          }else{
                   8141:            i=i-ncovmodel;
                   8142:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   8143:              fprintf(ficgp," (1.");
                   8144:          }
1.227     brouard  8145:          
1.223     brouard  8146:          if(ng != 1){
                   8147:            fprintf(ficgp,")/(1");
1.227     brouard  8148:            
1.264     brouard  8149:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8150:              if(nagesqr==0)
1.264     brouard  8151:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8152:              else /* nagesqr =1 */
1.264     brouard  8153:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8154:               
1.223     brouard  8155:              ij=1;
                   8156:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8157:                 if(cptcovage >0){ 
                   8158:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8159:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8160:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8161:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8162:                       ij++;
                   8163:                     }
                   8164:                   }
                   8165:                 }else
                   8166:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8167:              }
                   8168:              fprintf(ficgp,")");
                   8169:            }
                   8170:            fprintf(ficgp,")");
                   8171:            if(ng ==2)
1.276     brouard  8172:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8173:            else /* ng= 3 */
1.276     brouard  8174:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8175:          }else{ /* end ng <> 1 */
                   8176:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8177:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8178:          }
                   8179:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8180:            fprintf(ficgp,",");
                   8181:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8182:            fprintf(ficgp,",");
                   8183:          i=i+ncovmodel;
                   8184:        } /* end k */
                   8185:       } /* end k2 */
1.276     brouard  8186:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8187:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8188:     } /* end k1 */
1.223     brouard  8189:   } /* end ng */
                   8190:   /* avoid: */
                   8191:   fflush(ficgp); 
1.126     brouard  8192: }  /* end gnuplot */
                   8193: 
                   8194: 
                   8195: /*************** Moving average **************/
1.219     brouard  8196: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8197:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8198:    
1.222     brouard  8199:    int i, cpt, cptcod;
                   8200:    int modcovmax =1;
                   8201:    int mobilavrange, mob;
                   8202:    int iage=0;
1.288     brouard  8203:    int firstA1=0, firstA2=0;
1.222     brouard  8204: 
1.266     brouard  8205:    double sum=0., sumr=0.;
1.222     brouard  8206:    double age;
1.266     brouard  8207:    double *sumnewp, *sumnewm, *sumnewmr;
                   8208:    double *agemingood, *agemaxgood; 
                   8209:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8210:   
                   8211:   
1.278     brouard  8212:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8213:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8214: 
                   8215:    sumnewp = vector(1,ncovcombmax);
                   8216:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8217:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8218:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8219:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8220:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8221:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8222: 
                   8223:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8224:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8225:      sumnewp[cptcod]=0.;
1.266     brouard  8226:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8227:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8228:    }
                   8229:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8230:   
1.266     brouard  8231:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8232:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8233:      else mobilavrange=mobilav;
                   8234:      for (age=bage; age<=fage; age++)
                   8235:        for (i=1; i<=nlstate;i++)
                   8236:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8237:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8238:      /* We keep the original values on the extreme ages bage, fage and for 
                   8239:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8240:        we use a 5 terms etc. until the borders are no more concerned. 
                   8241:      */ 
                   8242:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8243:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8244:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8245:           sumnewm[cptcod]=0.;
                   8246:           for (i=1; i<=nlstate;i++){
1.222     brouard  8247:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8248:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8249:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8250:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8251:             }
                   8252:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8253:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8254:           } /* end i */
                   8255:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8256:         } /* end cptcod */
1.222     brouard  8257:        }/* end age */
                   8258:      }/* end mob */
1.266     brouard  8259:    }else{
                   8260:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8261:      return -1;
1.266     brouard  8262:    }
                   8263: 
                   8264:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8265:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8266:      if(invalidvarcomb[cptcod]){
                   8267:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8268:        continue;
                   8269:      }
1.219     brouard  8270: 
1.266     brouard  8271:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8272:        sumnewm[cptcod]=0.;
                   8273:        sumnewmr[cptcod]=0.;
                   8274:        for (i=1; i<=nlstate;i++){
                   8275:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8276:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8277:        }
                   8278:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8279:         agemingoodr[cptcod]=age;
                   8280:        }
                   8281:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8282:           agemingood[cptcod]=age;
                   8283:        }
                   8284:      } /* age */
                   8285:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8286:        sumnewm[cptcod]=0.;
1.266     brouard  8287:        sumnewmr[cptcod]=0.;
1.222     brouard  8288:        for (i=1; i<=nlstate;i++){
                   8289:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8290:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8291:        }
                   8292:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8293:         agemaxgoodr[cptcod]=age;
1.222     brouard  8294:        }
                   8295:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8296:         agemaxgood[cptcod]=age;
                   8297:        }
                   8298:      } /* age */
                   8299:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8300:      /* but they will change */
1.288     brouard  8301:      firstA1=0;firstA2=0;
1.266     brouard  8302:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8303:        sumnewm[cptcod]=0.;
                   8304:        sumnewmr[cptcod]=0.;
                   8305:        for (i=1; i<=nlstate;i++){
                   8306:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8307:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8308:        }
                   8309:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8310:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8311:           agemaxgoodr[cptcod]=age;  /* age min */
                   8312:           for (i=1; i<=nlstate;i++)
                   8313:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8314:         }else{ /* bad we change the value with the values of good ages */
                   8315:           for (i=1; i<=nlstate;i++){
                   8316:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8317:           } /* i */
                   8318:         } /* end bad */
                   8319:        }else{
                   8320:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8321:           agemaxgood[cptcod]=age;
                   8322:         }else{ /* bad we change the value with the values of good ages */
                   8323:           for (i=1; i<=nlstate;i++){
                   8324:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8325:           } /* i */
                   8326:         } /* end bad */
                   8327:        }/* end else */
                   8328:        sum=0.;sumr=0.;
                   8329:        for (i=1; i<=nlstate;i++){
                   8330:         sum+=mobaverage[(int)age][i][cptcod];
                   8331:         sumr+=probs[(int)age][i][cptcod];
                   8332:        }
                   8333:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8334:         if(!firstA1){
                   8335:           firstA1=1;
                   8336:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8337:         }
                   8338:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8339:        } /* end bad */
                   8340:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8341:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8342:         if(!firstA2){
                   8343:           firstA2=1;
                   8344:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8345:         }
                   8346:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8347:        } /* end bad */
                   8348:      }/* age */
1.266     brouard  8349: 
                   8350:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8351:        sumnewm[cptcod]=0.;
1.266     brouard  8352:        sumnewmr[cptcod]=0.;
1.222     brouard  8353:        for (i=1; i<=nlstate;i++){
                   8354:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8355:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8356:        } 
                   8357:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8358:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8359:           agemingoodr[cptcod]=age;
                   8360:           for (i=1; i<=nlstate;i++)
                   8361:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8362:         }else{ /* bad we change the value with the values of good ages */
                   8363:           for (i=1; i<=nlstate;i++){
                   8364:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8365:           } /* i */
                   8366:         } /* end bad */
                   8367:        }else{
                   8368:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8369:           agemingood[cptcod]=age;
                   8370:         }else{ /* bad */
                   8371:           for (i=1; i<=nlstate;i++){
                   8372:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8373:           } /* i */
                   8374:         } /* end bad */
                   8375:        }/* end else */
                   8376:        sum=0.;sumr=0.;
                   8377:        for (i=1; i<=nlstate;i++){
                   8378:         sum+=mobaverage[(int)age][i][cptcod];
                   8379:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8380:        }
1.266     brouard  8381:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8382:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8383:        } /* end bad */
                   8384:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8385:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8386:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8387:        } /* end bad */
                   8388:      }/* age */
1.266     brouard  8389: 
1.222     brouard  8390:                
                   8391:      for (age=bage; age<=fage; age++){
1.235     brouard  8392:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8393:        sumnewp[cptcod]=0.;
                   8394:        sumnewm[cptcod]=0.;
                   8395:        for (i=1; i<=nlstate;i++){
                   8396:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8397:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8398:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8399:        }
                   8400:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8401:      }
                   8402:      /* printf("\n"); */
                   8403:      /* } */
1.266     brouard  8404: 
1.222     brouard  8405:      /* brutal averaging */
1.266     brouard  8406:      /* for (i=1; i<=nlstate;i++){ */
                   8407:      /*   for (age=1; age<=bage; age++){ */
                   8408:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8409:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8410:      /*   }     */
                   8411:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8412:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8413:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8414:      /*   } */
                   8415:      /* } /\* end i status *\/ */
                   8416:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8417:      /*   for (age=1; age<=AGESUP; age++){ */
                   8418:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8419:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8420:      /*   } */
                   8421:      /* } */
1.222     brouard  8422:    }/* end cptcod */
1.266     brouard  8423:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8424:    free_vector(agemaxgood,1, ncovcombmax);
                   8425:    free_vector(agemingood,1, ncovcombmax);
                   8426:    free_vector(agemingoodr,1, ncovcombmax);
                   8427:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8428:    free_vector(sumnewm,1, ncovcombmax);
                   8429:    free_vector(sumnewp,1, ncovcombmax);
                   8430:    return 0;
                   8431:  }/* End movingaverage */
1.218     brouard  8432:  
1.126     brouard  8433: 
1.296     brouard  8434:  
1.126     brouard  8435: /************** Forecasting ******************/
1.296     brouard  8436: /* void prevforecast(char fileres[], double dateintmean, double anprojd, double mprojd, double jprojd, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anprojf, double p[], int cptcoveff)*/
                   8437: void prevforecast(char fileres[], double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8438:   /* dateintemean, mean date of interviews
                   8439:      dateprojd, year, month, day of starting projection 
                   8440:      dateprojf date of end of projection;year of end of projection (same day and month as proj1).
1.126     brouard  8441:      agemin, agemax range of age
                   8442:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8443:   */
1.296     brouard  8444:   /* double anprojd, mprojd, jprojd; */
                   8445:   /* double anprojf, mprojf, jprojf; */
1.267     brouard  8446:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8447:   double agec; /* generic age */
1.296     brouard  8448:   double agelim, ppij, yp,yp1,yp2;
1.126     brouard  8449:   double *popeffectif,*popcount;
                   8450:   double ***p3mat;
1.218     brouard  8451:   /* double ***mobaverage; */
1.126     brouard  8452:   char fileresf[FILENAMELENGTH];
                   8453: 
                   8454:   agelim=AGESUP;
1.211     brouard  8455:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8456:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8457:      We still use firstpass and lastpass as another selection.
                   8458:   */
1.214     brouard  8459:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8460:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8461:  
1.201     brouard  8462:   strcpy(fileresf,"F_"); 
                   8463:   strcat(fileresf,fileresu);
1.126     brouard  8464:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8465:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8466:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8467:   }
1.235     brouard  8468:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8469:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8470: 
1.225     brouard  8471:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8472: 
                   8473: 
                   8474:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8475:   if (stepm<=12) stepsize=1;
                   8476:   if(estepm < stepm){
                   8477:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8478:   }
1.270     brouard  8479:   else{
                   8480:     hstepm=estepm;   
                   8481:   }
                   8482:   if(estepm > stepm){ /* Yes every two year */
                   8483:     stepsize=2;
                   8484:   }
1.296     brouard  8485:   hstepm=hstepm/stepm;
1.126     brouard  8486: 
1.296     brouard  8487:   
                   8488:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8489:   /*                              fractional in yp1 *\/ */
                   8490:   /* aintmean=yp; */
                   8491:   /* yp2=modf((yp1*12),&yp); */
                   8492:   /* mintmean=yp; */
                   8493:   /* yp1=modf((yp2*30.5),&yp); */
                   8494:   /* jintmean=yp; */
                   8495:   /* if(jintmean==0) jintmean=1; */
                   8496:   /* if(mintmean==0) mintmean=1; */
1.126     brouard  8497: 
1.296     brouard  8498: 
                   8499:   /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */
                   8500:   /* date2dmy(dateprojd,&jprojd, &mprojd, &anprojd); */
                   8501:   /* date2dmy(dateprojf,&jprojf, &mprojf, &anprojf); */
1.227     brouard  8502:   i1=pow(2,cptcoveff);
1.126     brouard  8503:   if (cptcovn < 1){i1=1;}
                   8504:   
1.296     brouard  8505:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2); 
1.126     brouard  8506:   
                   8507:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8508:   
1.126     brouard  8509: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8510:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8511:   for(k=1; k<=i1;k++){
1.253     brouard  8512:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8513:       continue;
1.227     brouard  8514:     if(invalidvarcomb[k]){
                   8515:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8516:       continue;
                   8517:     }
                   8518:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8519:     for(j=1;j<=cptcoveff;j++) {
                   8520:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8521:     }
1.235     brouard  8522:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8523:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8524:     }
1.227     brouard  8525:     fprintf(ficresf," yearproj age");
                   8526:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8527:       for(i=1; i<=nlstate;i++)               
                   8528:        fprintf(ficresf," p%d%d",i,j);
                   8529:       fprintf(ficresf," wp.%d",j);
                   8530:     }
1.296     brouard  8531:     for (yearp=0; yearp<=(anprojf-anprojd);yearp +=stepsize) {
1.227     brouard  8532:       fprintf(ficresf,"\n");
1.296     brouard  8533:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jprojd,mprojd,anprojd+yearp);   
1.270     brouard  8534:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8535:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8536:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8537:        nhstepm = nhstepm/hstepm; 
                   8538:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8539:        oldm=oldms;savm=savms;
1.268     brouard  8540:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8541:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8542:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8543:        for (h=0; h<=nhstepm; h++){
                   8544:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8545:            break;
                   8546:          }
                   8547:        }
                   8548:        fprintf(ficresf,"\n");
                   8549:        for(j=1;j<=cptcoveff;j++) 
                   8550:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8551:        fprintf(ficresf,"%.f %.f ",anprojd+yearp,agec+h*hstepm/YEARM*stepm);
1.268     brouard  8552:        
                   8553:        for(j=1; j<=nlstate+ndeath;j++) {
                   8554:          ppij=0.;
                   8555:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8556:            if (mobilav>=1)
                   8557:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8558:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8559:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8560:            }
1.268     brouard  8561:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8562:          } /* end i */
                   8563:          fprintf(ficresf," %.3f", ppij);
                   8564:        }/* end j */
1.227     brouard  8565:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8566:       } /* end agec */
1.266     brouard  8567:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8568:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8569:     } /* end yearp */
                   8570:   } /* end  k */
1.219     brouard  8571:        
1.126     brouard  8572:   fclose(ficresf);
1.215     brouard  8573:   printf("End of Computing forecasting \n");
                   8574:   fprintf(ficlog,"End of Computing forecasting\n");
                   8575: 
1.126     brouard  8576: }
                   8577: 
1.269     brouard  8578: /************** Back Forecasting ******************/
1.296     brouard  8579:  /* void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
                   8580:  void prevbackforecast(char fileres[], double ***prevacurrent, double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8581:   /* back1, year, month, day of starting backprojection
1.267     brouard  8582:      agemin, agemax range of age
                   8583:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8584:      anback2 year of end of backprojection (same day and month as back1).
                   8585:      prevacurrent and prev are prevalences.
1.267     brouard  8586:   */
                   8587:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8588:   double agec; /* generic age */
1.302     brouard  8589:   double agelim, ppij, ppi, yp,yp1,yp2; /* ,jintmean,mintmean,aintmean;*/
1.267     brouard  8590:   double *popeffectif,*popcount;
                   8591:   double ***p3mat;
                   8592:   /* double ***mobaverage; */
                   8593:   char fileresfb[FILENAMELENGTH];
                   8594:  
1.268     brouard  8595:   agelim=AGEINF;
1.267     brouard  8596:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8597:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8598:      We still use firstpass and lastpass as another selection.
                   8599:   */
                   8600:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8601:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8602: 
                   8603:   /*Do we need to compute prevalence again?*/
                   8604: 
                   8605:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8606:   
                   8607:   strcpy(fileresfb,"FB_");
                   8608:   strcat(fileresfb,fileresu);
                   8609:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8610:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8611:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8612:   }
                   8613:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8614:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8615:   
                   8616:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8617:   
                   8618:    
                   8619:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8620:   if (stepm<=12) stepsize=1;
                   8621:   if(estepm < stepm){
                   8622:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8623:   }
1.270     brouard  8624:   else{
                   8625:     hstepm=estepm;   
                   8626:   }
                   8627:   if(estepm >= stepm){ /* Yes every two year */
                   8628:     stepsize=2;
                   8629:   }
1.267     brouard  8630:   
                   8631:   hstepm=hstepm/stepm;
1.296     brouard  8632:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8633:   /*                              fractional in yp1 *\/ */
                   8634:   /* aintmean=yp; */
                   8635:   /* yp2=modf((yp1*12),&yp); */
                   8636:   /* mintmean=yp; */
                   8637:   /* yp1=modf((yp2*30.5),&yp); */
                   8638:   /* jintmean=yp; */
                   8639:   /* if(jintmean==0) jintmean=1; */
                   8640:   /* if(mintmean==0) jintmean=1; */
1.267     brouard  8641:   
                   8642:   i1=pow(2,cptcoveff);
                   8643:   if (cptcovn < 1){i1=1;}
                   8644:   
1.296     brouard  8645:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
                   8646:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8647:   
                   8648:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8649:   
                   8650:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8651:   for(k=1; k<=i1;k++){
                   8652:     if(i1 != 1 && TKresult[nres]!= k)
                   8653:       continue;
                   8654:     if(invalidvarcomb[k]){
                   8655:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8656:       continue;
                   8657:     }
1.268     brouard  8658:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8659:     for(j=1;j<=cptcoveff;j++) {
                   8660:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8661:     }
                   8662:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8663:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8664:     }
                   8665:     fprintf(ficresfb," yearbproj age");
                   8666:     for(j=1; j<=nlstate+ndeath;j++){
                   8667:       for(i=1; i<=nlstate;i++)
1.268     brouard  8668:        fprintf(ficresfb," b%d%d",i,j);
                   8669:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8670:     }
1.296     brouard  8671:     for (yearp=0; yearp>=(anbackf-anbackd);yearp -=stepsize) {
1.267     brouard  8672:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8673:       fprintf(ficresfb,"\n");
1.296     brouard  8674:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jbackd,mbackd,anbackd+yearp);
1.273     brouard  8675:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8676:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8677:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8678:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8679:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8680:        nhstepm = nhstepm/hstepm;
                   8681:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8682:        oldm=oldms;savm=savms;
1.268     brouard  8683:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8684:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8685:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8686:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8687:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8688:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8689:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8690:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8691:            break;
                   8692:          }
                   8693:        }
                   8694:        fprintf(ficresfb,"\n");
                   8695:        for(j=1;j<=cptcoveff;j++)
                   8696:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8697:        fprintf(ficresfb,"%.f %.f ",anbackd+yearp,agec-h*hstepm/YEARM*stepm);
1.268     brouard  8698:        for(i=1; i<=nlstate+ndeath;i++) {
                   8699:          ppij=0.;ppi=0.;
                   8700:          for(j=1; j<=nlstate;j++) {
                   8701:            /* if (mobilav==1) */
1.269     brouard  8702:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8703:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8704:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8705:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8706:              /* else { */
                   8707:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8708:              /* } */
1.268     brouard  8709:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8710:          } /* end j */
                   8711:          if(ppi <0.99){
                   8712:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8713:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8714:          }
                   8715:          fprintf(ficresfb," %.3f", ppij);
                   8716:        }/* end j */
1.267     brouard  8717:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8718:       } /* end agec */
                   8719:     } /* end yearp */
                   8720:   } /* end k */
1.217     brouard  8721:   
1.267     brouard  8722:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8723:   
1.267     brouard  8724:   fclose(ficresfb);
                   8725:   printf("End of Computing Back forecasting \n");
                   8726:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8727:        
1.267     brouard  8728: }
1.217     brouard  8729: 
1.269     brouard  8730: /* Variance of prevalence limit: varprlim */
                   8731:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8732:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8733:  
                   8734:    char fileresvpl[FILENAMELENGTH];  
                   8735:    FILE *ficresvpl;
                   8736:    double **oldm, **savm;
                   8737:    double **varpl; /* Variances of prevalence limits by age */   
                   8738:    int i1, k, nres, j ;
                   8739:    
                   8740:     strcpy(fileresvpl,"VPL_");
                   8741:     strcat(fileresvpl,fileresu);
                   8742:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8743:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8744:       exit(0);
                   8745:     }
1.288     brouard  8746:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8747:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8748:     
                   8749:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8750:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8751:     
                   8752:     i1=pow(2,cptcoveff);
                   8753:     if (cptcovn < 1){i1=1;}
                   8754: 
                   8755:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8756:     for(k=1; k<=i1;k++){
                   8757:       if(i1 != 1 && TKresult[nres]!= k)
                   8758:        continue;
                   8759:       fprintf(ficresvpl,"\n#****** ");
                   8760:       printf("\n#****** ");
                   8761:       fprintf(ficlog,"\n#****** ");
                   8762:       for(j=1;j<=cptcoveff;j++) {
                   8763:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8764:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8765:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8766:       }
                   8767:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8768:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8769:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8770:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8771:       }        
                   8772:       fprintf(ficresvpl,"******\n");
                   8773:       printf("******\n");
                   8774:       fprintf(ficlog,"******\n");
                   8775:       
                   8776:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8777:       oldm=oldms;savm=savms;
                   8778:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8779:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8780:       /*}*/
                   8781:     }
                   8782:     
                   8783:     fclose(ficresvpl);
1.288     brouard  8784:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   8785:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  8786: 
                   8787:  }
                   8788: /* Variance of back prevalence: varbprlim */
                   8789:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8790:       /*------- Variance of back (stable) prevalence------*/
                   8791: 
                   8792:    char fileresvbl[FILENAMELENGTH];  
                   8793:    FILE  *ficresvbl;
                   8794: 
                   8795:    double **oldm, **savm;
                   8796:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8797:    int i1, k, nres, j ;
                   8798: 
                   8799:    strcpy(fileresvbl,"VBL_");
                   8800:    strcat(fileresvbl,fileresu);
                   8801:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8802:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8803:      exit(0);
                   8804:    }
                   8805:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8806:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8807:    
                   8808:    
                   8809:    i1=pow(2,cptcoveff);
                   8810:    if (cptcovn < 1){i1=1;}
                   8811:    
                   8812:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8813:      for(k=1; k<=i1;k++){
                   8814:        if(i1 != 1 && TKresult[nres]!= k)
                   8815:         continue;
                   8816:        fprintf(ficresvbl,"\n#****** ");
                   8817:        printf("\n#****** ");
                   8818:        fprintf(ficlog,"\n#****** ");
                   8819:        for(j=1;j<=cptcoveff;j++) {
                   8820:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8821:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8822:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8823:        }
                   8824:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8825:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8826:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8827:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8828:        }
                   8829:        fprintf(ficresvbl,"******\n");
                   8830:        printf("******\n");
                   8831:        fprintf(ficlog,"******\n");
                   8832:        
                   8833:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8834:        oldm=oldms;savm=savms;
                   8835:        
                   8836:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8837:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8838:        /*}*/
                   8839:      }
                   8840:    
                   8841:    fclose(ficresvbl);
                   8842:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8843:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8844: 
                   8845:  } /* End of varbprlim */
                   8846: 
1.126     brouard  8847: /************** Forecasting *****not tested NB*************/
1.227     brouard  8848: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8849:   
1.227     brouard  8850: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8851: /*   int *popage; */
                   8852: /*   double calagedatem, agelim, kk1, kk2; */
                   8853: /*   double *popeffectif,*popcount; */
                   8854: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8855: /*   /\* double ***mobaverage; *\/ */
                   8856: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8857: 
1.227     brouard  8858: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8859: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8860: /*   agelim=AGESUP; */
                   8861: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8862:   
1.227     brouard  8863: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8864:   
                   8865:   
1.227     brouard  8866: /*   strcpy(filerespop,"POP_");  */
                   8867: /*   strcat(filerespop,fileresu); */
                   8868: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8869: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8870: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8871: /*   } */
                   8872: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8873: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8874: 
1.227     brouard  8875: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8876: 
1.227     brouard  8877: /*   /\* if (mobilav!=0) { *\/ */
                   8878: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8879: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8880: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8881: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8882: /*   /\*   } *\/ */
                   8883: /*   /\* } *\/ */
1.126     brouard  8884: 
1.227     brouard  8885: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8886: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8887:   
1.227     brouard  8888: /*   agelim=AGESUP; */
1.126     brouard  8889:   
1.227     brouard  8890: /*   hstepm=1; */
                   8891: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8892:        
1.227     brouard  8893: /*   if (popforecast==1) { */
                   8894: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8895: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8896: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8897: /*     }  */
                   8898: /*     popage=ivector(0,AGESUP); */
                   8899: /*     popeffectif=vector(0,AGESUP); */
                   8900: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8901:     
1.227     brouard  8902: /*     i=1;    */
                   8903: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8904:     
1.227     brouard  8905: /*     imx=i; */
                   8906: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8907: /*   } */
1.218     brouard  8908:   
1.227     brouard  8909: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8910: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8911: /*       k=k+1; */
                   8912: /*       fprintf(ficrespop,"\n#******"); */
                   8913: /*       for(j=1;j<=cptcoveff;j++) { */
                   8914: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8915: /*       } */
                   8916: /*       fprintf(ficrespop,"******\n"); */
                   8917: /*       fprintf(ficrespop,"# Age"); */
                   8918: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8919: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8920:       
1.227     brouard  8921: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8922: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8923:        
1.227     brouard  8924: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8925: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8926: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8927:          
1.227     brouard  8928: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8929: /*       oldm=oldms;savm=savms; */
                   8930: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8931:          
1.227     brouard  8932: /*       for (h=0; h<=nhstepm; h++){ */
                   8933: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8934: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8935: /*         }  */
                   8936: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8937: /*           kk1=0.;kk2=0; */
                   8938: /*           for(i=1; i<=nlstate;i++) {               */
                   8939: /*             if (mobilav==1)  */
                   8940: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8941: /*             else { */
                   8942: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8943: /*             } */
                   8944: /*           } */
                   8945: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8946: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8947: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8948: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8949: /*           } */
                   8950: /*         } */
                   8951: /*         for(i=1; i<=nlstate;i++){ */
                   8952: /*           kk1=0.; */
                   8953: /*           for(j=1; j<=nlstate;j++){ */
                   8954: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8955: /*           } */
                   8956: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8957: /*         } */
1.218     brouard  8958:            
1.227     brouard  8959: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8960: /*           for(j=1; j<=nlstate;j++)  */
                   8961: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8962: /*       } */
                   8963: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8964: /*     } */
                   8965: /*       } */
1.218     brouard  8966:       
1.227     brouard  8967: /*       /\******\/ */
1.218     brouard  8968:       
1.227     brouard  8969: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8970: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8971: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8972: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8973: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8974:          
1.227     brouard  8975: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8976: /*       oldm=oldms;savm=savms; */
                   8977: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8978: /*       for (h=0; h<=nhstepm; h++){ */
                   8979: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8980: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8981: /*         }  */
                   8982: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8983: /*           kk1=0.;kk2=0; */
                   8984: /*           for(i=1; i<=nlstate;i++) {               */
                   8985: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8986: /*           } */
                   8987: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8988: /*         } */
                   8989: /*       } */
                   8990: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8991: /*     } */
                   8992: /*       } */
                   8993: /*     }  */
                   8994: /*   } */
1.218     brouard  8995:   
1.227     brouard  8996: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8997:   
1.227     brouard  8998: /*   if (popforecast==1) { */
                   8999: /*     free_ivector(popage,0,AGESUP); */
                   9000: /*     free_vector(popeffectif,0,AGESUP); */
                   9001: /*     free_vector(popcount,0,AGESUP); */
                   9002: /*   } */
                   9003: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9004: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9005: /*   fclose(ficrespop); */
                   9006: /* } /\* End of popforecast *\/ */
1.218     brouard  9007:  
1.126     brouard  9008: int fileappend(FILE *fichier, char *optionfich)
                   9009: {
                   9010:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   9011:     printf("Problem with file: %s\n", optionfich);
                   9012:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   9013:     return (0);
                   9014:   }
                   9015:   fflush(fichier);
                   9016:   return (1);
                   9017: }
                   9018: 
                   9019: 
                   9020: /**************** function prwizard **********************/
                   9021: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   9022: {
                   9023: 
                   9024:   /* Wizard to print covariance matrix template */
                   9025: 
1.164     brouard  9026:   char ca[32], cb[32];
                   9027:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  9028:   int numlinepar;
                   9029: 
                   9030:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9031:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9032:   for(i=1; i <=nlstate; i++){
                   9033:     jj=0;
                   9034:     for(j=1; j <=nlstate+ndeath; j++){
                   9035:       if(j==i) continue;
                   9036:       jj++;
                   9037:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   9038:       printf("%1d%1d",i,j);
                   9039:       fprintf(ficparo,"%1d%1d",i,j);
                   9040:       for(k=1; k<=ncovmodel;k++){
                   9041:        /*        printf(" %lf",param[i][j][k]); */
                   9042:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   9043:        printf(" 0.");
                   9044:        fprintf(ficparo," 0.");
                   9045:       }
                   9046:       printf("\n");
                   9047:       fprintf(ficparo,"\n");
                   9048:     }
                   9049:   }
                   9050:   printf("# Scales (for hessian or gradient estimation)\n");
                   9051:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   9052:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   9053:   for(i=1; i <=nlstate; i++){
                   9054:     jj=0;
                   9055:     for(j=1; j <=nlstate+ndeath; j++){
                   9056:       if(j==i) continue;
                   9057:       jj++;
                   9058:       fprintf(ficparo,"%1d%1d",i,j);
                   9059:       printf("%1d%1d",i,j);
                   9060:       fflush(stdout);
                   9061:       for(k=1; k<=ncovmodel;k++){
                   9062:        /*      printf(" %le",delti3[i][j][k]); */
                   9063:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   9064:        printf(" 0.");
                   9065:        fprintf(ficparo," 0.");
                   9066:       }
                   9067:       numlinepar++;
                   9068:       printf("\n");
                   9069:       fprintf(ficparo,"\n");
                   9070:     }
                   9071:   }
                   9072:   printf("# Covariance matrix\n");
                   9073: /* # 121 Var(a12)\n\ */
                   9074: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9075: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   9076: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   9077: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   9078: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   9079: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   9080: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   9081:   fflush(stdout);
                   9082:   fprintf(ficparo,"# Covariance matrix\n");
                   9083:   /* # 121 Var(a12)\n\ */
                   9084:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9085:   /* #   ...\n\ */
                   9086:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   9087:   
                   9088:   for(itimes=1;itimes<=2;itimes++){
                   9089:     jj=0;
                   9090:     for(i=1; i <=nlstate; i++){
                   9091:       for(j=1; j <=nlstate+ndeath; j++){
                   9092:        if(j==i) continue;
                   9093:        for(k=1; k<=ncovmodel;k++){
                   9094:          jj++;
                   9095:          ca[0]= k+'a'-1;ca[1]='\0';
                   9096:          if(itimes==1){
                   9097:            printf("#%1d%1d%d",i,j,k);
                   9098:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   9099:          }else{
                   9100:            printf("%1d%1d%d",i,j,k);
                   9101:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   9102:            /*  printf(" %.5le",matcov[i][j]); */
                   9103:          }
                   9104:          ll=0;
                   9105:          for(li=1;li <=nlstate; li++){
                   9106:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   9107:              if(lj==li) continue;
                   9108:              for(lk=1;lk<=ncovmodel;lk++){
                   9109:                ll++;
                   9110:                if(ll<=jj){
                   9111:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   9112:                  if(ll<jj){
                   9113:                    if(itimes==1){
                   9114:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9115:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9116:                    }else{
                   9117:                      printf(" 0.");
                   9118:                      fprintf(ficparo," 0.");
                   9119:                    }
                   9120:                  }else{
                   9121:                    if(itimes==1){
                   9122:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   9123:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   9124:                    }else{
                   9125:                      printf(" 0.");
                   9126:                      fprintf(ficparo," 0.");
                   9127:                    }
                   9128:                  }
                   9129:                }
                   9130:              } /* end lk */
                   9131:            } /* end lj */
                   9132:          } /* end li */
                   9133:          printf("\n");
                   9134:          fprintf(ficparo,"\n");
                   9135:          numlinepar++;
                   9136:        } /* end k*/
                   9137:       } /*end j */
                   9138:     } /* end i */
                   9139:   } /* end itimes */
                   9140: 
                   9141: } /* end of prwizard */
                   9142: /******************* Gompertz Likelihood ******************************/
                   9143: double gompertz(double x[])
                   9144: { 
1.302     brouard  9145:   double A=0.0,B=0.,L=0.0,sump=0.,num=0.;
1.126     brouard  9146:   int i,n=0; /* n is the size of the sample */
                   9147: 
1.220     brouard  9148:   for (i=1;i<=imx ; i++) {
1.126     brouard  9149:     sump=sump+weight[i];
                   9150:     /*    sump=sump+1;*/
                   9151:     num=num+1;
                   9152:   }
1.302     brouard  9153:   L=0.0;
                   9154:   /* agegomp=AGEGOMP; */
1.126     brouard  9155:   /* for (i=0; i<=imx; i++) 
                   9156:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9157: 
1.302     brouard  9158:   for (i=1;i<=imx ; i++) {
                   9159:     /* mu(a)=mu(agecomp)*exp(teta*(age-agegomp))
                   9160:        mu(a)=x[1]*exp(x[2]*(age-agegomp)); x[1] and x[2] are per year.
                   9161:      * L= Product mu(agedeces)exp(-\int_ageexam^agedc mu(u) du ) for a death between agedc (in month) 
                   9162:      *   and agedc +1 month, cens[i]=0: log(x[1]/YEARM)
                   9163:      * +
                   9164:      * exp(-\int_ageexam^agecens mu(u) du ) when censored, cens[i]=1
                   9165:      */
                   9166:      if (wav[i] > 1 || agedc[i] < AGESUP) {
                   9167:        if (cens[i] == 1){
                   9168:         A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   9169:        } else if (cens[i] == 0){
1.126     brouard  9170:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
1.302     brouard  9171:          +log(x[1]/YEARM) +x[2]*(agedc[i]-agegomp)+log(YEARM);
                   9172:       } else
                   9173:         printf("Gompertz cens[%d] neither 1 nor 0\n",i);
1.126     brouard  9174:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
1.302     brouard  9175:        L=L+A*weight[i];
1.126     brouard  9176:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
1.302     brouard  9177:      }
                   9178:   }
1.126     brouard  9179: 
1.302     brouard  9180:   /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
1.126     brouard  9181:  
                   9182:   return -2*L*num/sump;
                   9183: }
                   9184: 
1.136     brouard  9185: #ifdef GSL
                   9186: /******************* Gompertz_f Likelihood ******************************/
                   9187: double gompertz_f(const gsl_vector *v, void *params)
                   9188: { 
1.302     brouard  9189:   double A=0.,B=0.,LL=0.0,sump=0.,num=0.;
1.136     brouard  9190:   double *x= (double *) v->data;
                   9191:   int i,n=0; /* n is the size of the sample */
                   9192: 
                   9193:   for (i=0;i<=imx-1 ; i++) {
                   9194:     sump=sump+weight[i];
                   9195:     /*    sump=sump+1;*/
                   9196:     num=num+1;
                   9197:   }
                   9198:  
                   9199:  
                   9200:   /* for (i=0; i<=imx; i++) 
                   9201:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9202:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9203:   for (i=1;i<=imx ; i++)
                   9204:     {
                   9205:       if (cens[i] == 1 && wav[i]>1)
                   9206:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9207:       
                   9208:       if (cens[i] == 0 && wav[i]>1)
                   9209:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9210:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9211:       
                   9212:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9213:       if (wav[i] > 1 ) { /* ??? */
                   9214:        LL=LL+A*weight[i];
                   9215:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9216:       }
                   9217:     }
                   9218: 
                   9219:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9220:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9221:  
                   9222:   return -2*LL*num/sump;
                   9223: }
                   9224: #endif
                   9225: 
1.126     brouard  9226: /******************* Printing html file ***********/
1.201     brouard  9227: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9228:                  int lastpass, int stepm, int weightopt, char model[],\
                   9229:                  int imx,  double p[],double **matcov,double agemortsup){
                   9230:   int i,k;
                   9231: 
                   9232:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9233:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9234:   for (i=1;i<=2;i++) 
                   9235:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9236:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9237:   fprintf(fichtm,"</ul>");
                   9238: 
                   9239: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9240: 
                   9241:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9242: 
                   9243:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9244:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9245: 
                   9246:  
                   9247:   fflush(fichtm);
                   9248: }
                   9249: 
                   9250: /******************* Gnuplot file **************/
1.201     brouard  9251: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9252: 
                   9253:   char dirfileres[132],optfileres[132];
1.164     brouard  9254: 
1.126     brouard  9255:   int ng;
                   9256: 
                   9257: 
                   9258:   /*#ifdef windows */
                   9259:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9260:     /*#endif */
                   9261: 
                   9262: 
                   9263:   strcpy(dirfileres,optionfilefiname);
                   9264:   strcpy(optfileres,"vpl");
1.199     brouard  9265:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9266:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9267:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9268:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9269:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9270: 
                   9271: } 
                   9272: 
1.136     brouard  9273: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9274: {
1.126     brouard  9275: 
1.136     brouard  9276:   /*-------- data file ----------*/
                   9277:   FILE *fic;
                   9278:   char dummy[]="                         ";
1.240     brouard  9279:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9280:   int lstra;
1.136     brouard  9281:   int linei, month, year,iout;
1.302     brouard  9282:   int noffset=0; /* This is the offset if BOM data file */
1.136     brouard  9283:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9284:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9285:   char *stratrunc;
1.223     brouard  9286: 
1.240     brouard  9287:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9288:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9289: 
1.240     brouard  9290:   for(v=1; v <=ncovcol;v++){
                   9291:     DummyV[v]=0;
                   9292:     FixedV[v]=0;
                   9293:   }
                   9294:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9295:     DummyV[v]=1;
                   9296:     FixedV[v]=0;
                   9297:   }
                   9298:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9299:     DummyV[v]=0;
                   9300:     FixedV[v]=1;
                   9301:   }
                   9302:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9303:     DummyV[v]=1;
                   9304:     FixedV[v]=1;
                   9305:   }
                   9306:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9307:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9308:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9309:   }
1.126     brouard  9310: 
1.136     brouard  9311:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9312:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9313:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9314:   }
1.126     brouard  9315: 
1.302     brouard  9316:     /* Is it a BOM UTF-8 Windows file? */
                   9317:   /* First data line */
                   9318:   linei=0;
                   9319:   while(fgets(line, MAXLINE, fic)) {
                   9320:     noffset=0;
                   9321:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   9322:     {
                   9323:       noffset=noffset+3;
                   9324:       printf("# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);fflush(stdout);
                   9325:       fprintf(ficlog,"# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);
                   9326:       fflush(ficlog); return 1;
                   9327:     }
                   9328:     /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   9329:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
                   9330:     {
                   9331:       noffset=noffset+2;
1.304     brouard  9332:       printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9333:       fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9334:       fflush(ficlog); return 1;
                   9335:     }
                   9336:     else if( line[0] == 0 && line[1] == 0)
                   9337:     {
                   9338:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   9339:        noffset=noffset+4;
1.304     brouard  9340:        printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9341:        fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9342:        fflush(ficlog); return 1;
                   9343:       }
                   9344:     } else{
                   9345:       ;/*printf(" Not a BOM file\n");*/
                   9346:     }
                   9347:         /* If line starts with a # it is a comment */
                   9348:     if (line[noffset] == '#') {
                   9349:       linei=linei+1;
                   9350:       break;
                   9351:     }else{
                   9352:       break;
                   9353:     }
                   9354:   }
                   9355:   fclose(fic);
                   9356:   if((fic=fopen(datafile,"r"))==NULL)    {
                   9357:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9358:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
                   9359:   }
                   9360:   /* Not a Bom file */
                   9361:   
1.136     brouard  9362:   i=1;
                   9363:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9364:     linei=linei+1;
                   9365:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9366:       if(line[j] == '\t')
                   9367:        line[j] = ' ';
                   9368:     }
                   9369:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9370:       ;
                   9371:     };
                   9372:     line[j+1]=0;  /* Trims blanks at end of line */
                   9373:     if(line[0]=='#'){
                   9374:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9375:       printf("Comment line\n%s\n",line);
                   9376:       continue;
                   9377:     }
                   9378:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9379:     strcpy(line, linetmp);
1.223     brouard  9380:     
                   9381:     /* Loops on waves */
                   9382:     for (j=maxwav;j>=1;j--){
                   9383:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9384:        cutv(stra, strb, line, ' '); 
                   9385:        if(strb[0]=='.') { /* Missing value */
                   9386:          lval=-1;
                   9387:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9388:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9389:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9390:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9391:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9392:            return 1;
                   9393:          }
                   9394:        }else{
                   9395:          errno=0;
                   9396:          /* what_kind_of_number(strb); */
                   9397:          dval=strtod(strb,&endptr); 
                   9398:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9399:          /* if(strb != endptr && *endptr == '\0') */
                   9400:          /*    dval=dlval; */
                   9401:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9402:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9403:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9404:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9405:            return 1;
                   9406:          }
                   9407:          cotqvar[j][iv][i]=dval; 
                   9408:          cotvar[j][ntv+iv][i]=dval; 
                   9409:        }
                   9410:        strcpy(line,stra);
1.223     brouard  9411:       }/* end loop ntqv */
1.225     brouard  9412:       
1.223     brouard  9413:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9414:        cutv(stra, strb, line, ' '); 
                   9415:        if(strb[0]=='.') { /* Missing value */
                   9416:          lval=-1;
                   9417:        }else{
                   9418:          errno=0;
                   9419:          lval=strtol(strb,&endptr,10); 
                   9420:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9421:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9422:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9423:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9424:            return 1;
                   9425:          }
                   9426:        }
                   9427:        if(lval <-1 || lval >1){
                   9428:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9429:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9430:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9431:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9432:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9433:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9434:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9435:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9436:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9437:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9438:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9439:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9440:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9441:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9442:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9443:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9444:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9445:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9446:          return 1;
                   9447:        }
                   9448:        cotvar[j][iv][i]=(double)(lval);
                   9449:        strcpy(line,stra);
1.223     brouard  9450:       }/* end loop ntv */
1.225     brouard  9451:       
1.223     brouard  9452:       /* Statuses  at wave */
1.137     brouard  9453:       cutv(stra, strb, line, ' '); 
1.223     brouard  9454:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9455:        lval=-1;
1.136     brouard  9456:       }else{
1.238     brouard  9457:        errno=0;
                   9458:        lval=strtol(strb,&endptr,10); 
                   9459:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9460:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9461:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9462:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9463:          return 1;
                   9464:        }
1.136     brouard  9465:       }
1.225     brouard  9466:       
1.136     brouard  9467:       s[j][i]=lval;
1.225     brouard  9468:       
1.223     brouard  9469:       /* Date of Interview */
1.136     brouard  9470:       strcpy(line,stra);
                   9471:       cutv(stra, strb,line,' ');
1.169     brouard  9472:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9473:       }
1.169     brouard  9474:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9475:        month=99;
                   9476:        year=9999;
1.136     brouard  9477:       }else{
1.225     brouard  9478:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9479:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9480:        return 1;
1.136     brouard  9481:       }
                   9482:       anint[j][i]= (double) year; 
1.302     brouard  9483:       mint[j][i]= (double)month;
                   9484:       /* if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){ */
                   9485:       /*       printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9486:       /*       fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9487:       /* } */
1.136     brouard  9488:       strcpy(line,stra);
1.223     brouard  9489:     } /* End loop on waves */
1.225     brouard  9490:     
1.223     brouard  9491:     /* Date of death */
1.136     brouard  9492:     cutv(stra, strb,line,' '); 
1.169     brouard  9493:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9494:     }
1.169     brouard  9495:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9496:       month=99;
                   9497:       year=9999;
                   9498:     }else{
1.141     brouard  9499:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9500:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9501:       return 1;
1.136     brouard  9502:     }
                   9503:     andc[i]=(double) year; 
                   9504:     moisdc[i]=(double) month; 
                   9505:     strcpy(line,stra);
                   9506:     
1.223     brouard  9507:     /* Date of birth */
1.136     brouard  9508:     cutv(stra, strb,line,' '); 
1.169     brouard  9509:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9510:     }
1.169     brouard  9511:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9512:       month=99;
                   9513:       year=9999;
                   9514:     }else{
1.141     brouard  9515:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9516:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9517:       return 1;
1.136     brouard  9518:     }
                   9519:     if (year==9999) {
1.141     brouard  9520:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9521:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9522:       return 1;
                   9523:       
1.136     brouard  9524:     }
                   9525:     annais[i]=(double)(year);
1.302     brouard  9526:     moisnais[i]=(double)(month);
                   9527:     for (j=1;j<=maxwav;j++){
                   9528:       if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){
                   9529:        printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j,(int)moisnais[i],(int)annais[i]);
                   9530:        fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j, (int)moisnais[i],(int)annais[i]);
                   9531:       }
                   9532:     }
                   9533: 
1.136     brouard  9534:     strcpy(line,stra);
1.225     brouard  9535:     
1.223     brouard  9536:     /* Sample weight */
1.136     brouard  9537:     cutv(stra, strb,line,' '); 
                   9538:     errno=0;
                   9539:     dval=strtod(strb,&endptr); 
                   9540:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9541:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9542:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9543:       fflush(ficlog);
                   9544:       return 1;
                   9545:     }
                   9546:     weight[i]=dval; 
                   9547:     strcpy(line,stra);
1.225     brouard  9548:     
1.223     brouard  9549:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9550:       cutv(stra, strb, line, ' '); 
                   9551:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9552:        lval=-1;
1.311     brouard  9553:        coqvar[iv][i]=NAN; 
                   9554:        covar[ncovcol+iv][i]=NAN; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9555:       }else{
1.225     brouard  9556:        errno=0;
                   9557:        /* what_kind_of_number(strb); */
                   9558:        dval=strtod(strb,&endptr);
                   9559:        /* if(strb != endptr && *endptr == '\0') */
                   9560:        /*   dval=dlval; */
                   9561:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9562:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9563:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9564:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9565:          return 1;
                   9566:        }
                   9567:        coqvar[iv][i]=dval; 
1.226     brouard  9568:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9569:       }
                   9570:       strcpy(line,stra);
                   9571:     }/* end loop nqv */
1.136     brouard  9572:     
1.223     brouard  9573:     /* Covariate values */
1.136     brouard  9574:     for (j=ncovcol;j>=1;j--){
                   9575:       cutv(stra, strb,line,' '); 
1.223     brouard  9576:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9577:        lval=-1;
1.136     brouard  9578:       }else{
1.225     brouard  9579:        errno=0;
                   9580:        lval=strtol(strb,&endptr,10); 
                   9581:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9582:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9583:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9584:          return 1;
                   9585:        }
1.136     brouard  9586:       }
                   9587:       if(lval <-1 || lval >1){
1.225     brouard  9588:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9589:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9590:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9591:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9592:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9593:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9594:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9595:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9596:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9597:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9598:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9599:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9600:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9601:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9602:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9603:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9604:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9605:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9606:        return 1;
1.136     brouard  9607:       }
                   9608:       covar[j][i]=(double)(lval);
                   9609:       strcpy(line,stra);
                   9610:     }  
                   9611:     lstra=strlen(stra);
1.225     brouard  9612:     
1.136     brouard  9613:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9614:       stratrunc = &(stra[lstra-9]);
                   9615:       num[i]=atol(stratrunc);
                   9616:     }
                   9617:     else
                   9618:       num[i]=atol(stra);
                   9619:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9620:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9621:     
                   9622:     i=i+1;
                   9623:   } /* End loop reading  data */
1.225     brouard  9624:   
1.136     brouard  9625:   *imax=i-1; /* Number of individuals */
                   9626:   fclose(fic);
1.225     brouard  9627:   
1.136     brouard  9628:   return (0);
1.164     brouard  9629:   /* endread: */
1.225     brouard  9630:   printf("Exiting readdata: ");
                   9631:   fclose(fic);
                   9632:   return (1);
1.223     brouard  9633: }
1.126     brouard  9634: 
1.234     brouard  9635: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9636:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9637:   while (*p2 == ' ')
1.234     brouard  9638:     p2++; 
                   9639:   /* while ((*p1++ = *p2++) !=0) */
                   9640:   /*   ; */
                   9641:   /* do */
                   9642:   /*   while (*p2 == ' ') */
                   9643:   /*     p2++; */
                   9644:   /* while (*p1++ == *p2++); */
                   9645:   *stri=p2; 
1.145     brouard  9646: }
                   9647: 
1.235     brouard  9648: int decoderesult ( char resultline[], int nres)
1.230     brouard  9649: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9650: {
1.235     brouard  9651:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9652:   char resultsav[MAXLINE];
1.234     brouard  9653:   int resultmodel[MAXLINE];
                   9654:   int modelresult[MAXLINE];
1.230     brouard  9655:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9656: 
1.234     brouard  9657:   removefirstspace(&resultline);
1.230     brouard  9658: 
                   9659:   if (strstr(resultline,"v") !=0){
                   9660:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9661:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9662:     return 1;
                   9663:   }
                   9664:   trimbb(resultsav, resultline);
                   9665:   if (strlen(resultsav) >1){
                   9666:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9667:   }
1.253     brouard  9668:   if(j == 0){ /* Resultline but no = */
                   9669:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9670:     return (0);
                   9671:   }
1.234     brouard  9672:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
1.310     brouard  9673:     printf("ERROR: the number of variables in the resultline, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
                   9674:     fprintf(ficlog,"ERROR: the number of variables in the resultline, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
1.234     brouard  9675:   }
                   9676:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9677:     if(nbocc(resultsav,'=') >1){
                   9678:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
1.310     brouard  9679:                                      resultsav= V4=1 V5=25.1 V3=0 stra= V5=25.1 V3=0 strb= V4=1 */
1.234     brouard  9680:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9681:     }else
                   9682:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9683:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9684:     
1.230     brouard  9685:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9686:     Tvarsel[k]=atoi(strc);
                   9687:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9688:     /* cptcovsel++;     */
                   9689:     if (nbocc(stra,'=') >0)
                   9690:       strcpy(resultsav,stra); /* and analyzes it */
                   9691:   }
1.235     brouard  9692:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9693:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9694:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9695:       match=0;
1.236     brouard  9696:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9697:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9698:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9699:          match=1;
                   9700:          break;
                   9701:        }
                   9702:       }
                   9703:       if(match == 0){
1.310     brouard  9704:        printf("Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9705:        fprintf(ficlog,"Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9706:        return 1;
1.234     brouard  9707:       }
                   9708:     }
                   9709:   }
1.235     brouard  9710:   /* Checking for missing or useless values in comparison of current model needs */
                   9711:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9712:     match=0;
1.235     brouard  9713:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9714:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9715:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9716:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9717:          ++match;
                   9718:        }
                   9719:       }
                   9720:     }
                   9721:     if(match == 0){
                   9722:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
1.310     brouard  9723:       fprintf(ficlog,"Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9724:       return 1;
1.234     brouard  9725:     }else if(match > 1){
                   9726:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
1.310     brouard  9727:       fprintf(ficlog,"Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9728:       return 1;
1.234     brouard  9729:     }
                   9730:   }
1.235     brouard  9731:       
1.234     brouard  9732:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9733:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9734:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9735:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9736:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9737:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9738:   /*    1 0 0 0 */
                   9739:   /*    2 1 0 0 */
                   9740:   /*    3 0 1 0 */ 
                   9741:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9742:   /*    5 0 0 1 */
                   9743:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9744:   /*    7 0 1 1 */
                   9745:   /*    8 1 1 1 */
1.237     brouard  9746:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9747:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9748:   /* V5*age V5 known which value for nres?  */
                   9749:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9750:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9751:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9752:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9753:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9754:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9755:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9756:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9757:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9758:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9759:       k4++;;
                   9760:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9761:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9762:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9763:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9764:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9765:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9766:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9767:       k4q++;;
                   9768:     }
                   9769:   }
1.234     brouard  9770:   
1.235     brouard  9771:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9772:   return (0);
                   9773: }
1.235     brouard  9774: 
1.230     brouard  9775: int decodemodel( char model[], int lastobs)
                   9776:  /**< This routine decodes the model and returns:
1.224     brouard  9777:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9778:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9779:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9780:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9781:        * - cptcovage number of covariates with age*products =2
                   9782:        * - cptcovs number of simple covariates
                   9783:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9784:        *     which is a new column after the 9 (ncovcol) variables. 
                   9785:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9786:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9787:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9788:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9789:        */
1.136     brouard  9790: {
1.238     brouard  9791:   int i, j, k, ks, v;
1.227     brouard  9792:   int  j1, k1, k2, k3, k4;
1.136     brouard  9793:   char modelsav[80];
1.145     brouard  9794:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9795:   char *strpt;
1.136     brouard  9796: 
1.145     brouard  9797:   /*removespace(model);*/
1.136     brouard  9798:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9799:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9800:     if (strstr(model,"AGE") !=0){
1.192     brouard  9801:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9802:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9803:       return 1;
                   9804:     }
1.141     brouard  9805:     if (strstr(model,"v") !=0){
                   9806:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9807:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9808:       return 1;
                   9809:     }
1.187     brouard  9810:     strcpy(modelsav,model); 
                   9811:     if ((strpt=strstr(model,"age*age")) !=0){
                   9812:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9813:       if(strpt != model){
1.234     brouard  9814:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9815:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9816:  corresponding column of parameters.\n",model);
1.234     brouard  9817:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9818:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9819:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9820:        return 1;
1.225     brouard  9821:       }
1.187     brouard  9822:       nagesqr=1;
                   9823:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9824:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9825:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9826:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9827:       else 
1.234     brouard  9828:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9829:     }else
                   9830:       nagesqr=0;
                   9831:     if (strlen(modelsav) >1){
                   9832:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9833:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9834:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9835:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9836:                     * cst, age and age*age 
                   9837:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9838:       /* including age products which are counted in cptcovage.
                   9839:        * but the covariates which are products must be treated 
                   9840:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9841:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9842:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9843:       
                   9844:       
1.187     brouard  9845:       /*   Design
                   9846:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9847:        *  <          ncovcol=8                >
                   9848:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9849:        *   k=  1    2      3       4     5       6      7        8
                   9850:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9851:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9852:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9853:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9854:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9855:        *  Tage[++cptcovage]=k
                   9856:        *       if products, new covar are created after ncovcol with k1
                   9857:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9858:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9859:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9860:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9861:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9862:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9863:        *  <          ncovcol=8                >
                   9864:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9865:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9866:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9867:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9868:        * p Tprod[1]@2={                         6, 5}
                   9869:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9870:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9871:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9872:        *How to reorganize?
                   9873:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9874:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9875:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9876:        * Struct []
                   9877:        */
1.225     brouard  9878:       
1.187     brouard  9879:       /* This loop fills the array Tvar from the string 'model'.*/
                   9880:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9881:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9882:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9883:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9884:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9885:       /*       k=1 Tvar[1]=2 (from V2) */
                   9886:       /*       k=5 Tvar[5] */
                   9887:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9888:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9889:       /*       } */
1.198     brouard  9890:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9891:       /*
                   9892:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9893:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9894:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9895:       }
1.187     brouard  9896:       cptcovage=0;
                   9897:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9898:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9899:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9900:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9901:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9902:        /*scanf("%d",i);*/
                   9903:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9904:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9905:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9906:            /* covar is not filled and then is empty */
                   9907:            cptcovprod--;
                   9908:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9909:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9910:            Typevar[k]=1;  /* 1 for age product */
                   9911:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9912:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9913:            /*printf("stre=%s ", stre);*/
                   9914:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9915:            cptcovprod--;
                   9916:            cutl(stre,strb,strc,'V');
                   9917:            Tvar[k]=atoi(stre);
                   9918:            Typevar[k]=1;  /* 1 for age product */
                   9919:            cptcovage++;
                   9920:            Tage[cptcovage]=k;
                   9921:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9922:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9923:            cptcovn++;
                   9924:            cptcovprodnoage++;k1++;
                   9925:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9926:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9927:                                                because this model-covariate is a construction we invent a new column
                   9928:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9929:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9930:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9931:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9932:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9933:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9934:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9935:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9936:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9937:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9938:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9939:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9940:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9941:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9942:            for (i=1; i<=lastobs;i++){
                   9943:              /* Computes the new covariate which is a product of
                   9944:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9945:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9946:            }
                   9947:          } /* End age is not in the model */
                   9948:        } /* End if model includes a product */
                   9949:        else { /* no more sum */
                   9950:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9951:          /*  scanf("%d",i);*/
                   9952:          cutl(strd,strc,strb,'V');
                   9953:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9954:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9955:          Tvar[k]=atoi(strd);
                   9956:          Typevar[k]=0;  /* 0 for simple covariates */
                   9957:        }
                   9958:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9959:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9960:                                  scanf("%d",i);*/
1.187     brouard  9961:       } /* end of loop + on total covariates */
                   9962:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9963:   } /* end if strlen(model == 0) */
1.136     brouard  9964:   
                   9965:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9966:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9967:   
1.136     brouard  9968:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9969:      printf("cptcovprod=%d ", cptcovprod);
                   9970:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9971:      scanf("%d ",i);*/
                   9972: 
                   9973: 
1.230     brouard  9974: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9975:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9976: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9977:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9978:    k =           1    2   3     4       5       6      7      8        9
                   9979:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9980:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9981:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9982:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9983:          Tmodelind[combination of covar]=k;
1.225     brouard  9984: */  
                   9985: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9986:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9987:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9988:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9989:   printf("Model=%s\n\
                   9990: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9991: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9992: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9993:   fprintf(ficlog,"Model=%s\n\
                   9994: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9995: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9996: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  9997:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9998:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9999:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  10000:       Fixed[k]= 0;
                   10001:       Dummy[k]= 0;
1.225     brouard  10002:       ncoveff++;
1.232     brouard  10003:       ncovf++;
1.234     brouard  10004:       nsd++;
                   10005:       modell[k].maintype= FTYPE;
                   10006:       TvarsD[nsd]=Tvar[k];
                   10007:       TvarsDind[nsd]=k;
                   10008:       TvarF[ncovf]=Tvar[k];
                   10009:       TvarFind[ncovf]=k;
                   10010:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10011:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10012:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   10013:       Fixed[k]= 0;
                   10014:       Dummy[k]= 0;
                   10015:       ncoveff++;
                   10016:       ncovf++;
                   10017:       modell[k].maintype= FTYPE;
                   10018:       TvarF[ncovf]=Tvar[k];
                   10019:       TvarFind[ncovf]=k;
1.230     brouard  10020:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  10021:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  10022:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  10023:       Fixed[k]= 0;
                   10024:       Dummy[k]= 1;
1.230     brouard  10025:       nqfveff++;
1.234     brouard  10026:       modell[k].maintype= FTYPE;
                   10027:       modell[k].subtype= FQ;
                   10028:       nsq++;
                   10029:       TvarsQ[nsq]=Tvar[k];
                   10030:       TvarsQind[nsq]=k;
1.232     brouard  10031:       ncovf++;
1.234     brouard  10032:       TvarF[ncovf]=Tvar[k];
                   10033:       TvarFind[ncovf]=k;
1.231     brouard  10034:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  10035:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  10036:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  10037:       Fixed[k]= 1;
                   10038:       Dummy[k]= 0;
1.225     brouard  10039:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  10040:       modell[k].maintype= VTYPE;
                   10041:       modell[k].subtype= VD;
                   10042:       nsd++;
                   10043:       TvarsD[nsd]=Tvar[k];
                   10044:       TvarsDind[nsd]=k;
                   10045:       ncovv++; /* Only simple time varying variables */
                   10046:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10047:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10048:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   10049:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  10050:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   10051:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  10052:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  10053:       Fixed[k]= 1;
                   10054:       Dummy[k]= 1;
                   10055:       nqtveff++;
                   10056:       modell[k].maintype= VTYPE;
                   10057:       modell[k].subtype= VQ;
                   10058:       ncovv++; /* Only simple time varying variables */
                   10059:       nsq++;
                   10060:       TvarsQ[nsq]=Tvar[k];
                   10061:       TvarsQind[nsq]=k;
                   10062:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10063:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10064:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   10065:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  10066:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   10067:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   10068:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  10069:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  10070:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  10071:       ncova++;
                   10072:       TvarA[ncova]=Tvar[k];
                   10073:       TvarAind[ncova]=k;
1.231     brouard  10074:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  10075:        Fixed[k]= 2;
                   10076:        Dummy[k]= 2;
                   10077:        modell[k].maintype= ATYPE;
                   10078:        modell[k].subtype= APFD;
                   10079:        /* ncoveff++; */
1.227     brouard  10080:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  10081:        Fixed[k]= 2;
                   10082:        Dummy[k]= 3;
                   10083:        modell[k].maintype= ATYPE;
                   10084:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   10085:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  10086:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  10087:        Fixed[k]= 3;
                   10088:        Dummy[k]= 2;
                   10089:        modell[k].maintype= ATYPE;
                   10090:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   10091:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  10092:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10093:        Fixed[k]= 3;
                   10094:        Dummy[k]= 3;
                   10095:        modell[k].maintype= ATYPE;
                   10096:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   10097:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  10098:       }
                   10099:     }else if (Typevar[k] == 2) {  /* product without age */
                   10100:       k1=Tposprod[k];
                   10101:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  10102:        if(Tvard[k1][2] <=ncovcol){
                   10103:          Fixed[k]= 1;
                   10104:          Dummy[k]= 0;
                   10105:          modell[k].maintype= FTYPE;
                   10106:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   10107:          ncovf++; /* Fixed variables without age */
                   10108:          TvarF[ncovf]=Tvar[k];
                   10109:          TvarFind[ncovf]=k;
                   10110:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10111:          Fixed[k]= 0;  /* or 2 ?*/
                   10112:          Dummy[k]= 1;
                   10113:          modell[k].maintype= FTYPE;
                   10114:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   10115:          ncovf++; /* Varying variables without age */
                   10116:          TvarF[ncovf]=Tvar[k];
                   10117:          TvarFind[ncovf]=k;
                   10118:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10119:          Fixed[k]= 1;
                   10120:          Dummy[k]= 0;
                   10121:          modell[k].maintype= VTYPE;
                   10122:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   10123:          ncovv++; /* Varying variables without age */
                   10124:          TvarV[ncovv]=Tvar[k];
                   10125:          TvarVind[ncovv]=k;
                   10126:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10127:          Fixed[k]= 1;
                   10128:          Dummy[k]= 1;
                   10129:          modell[k].maintype= VTYPE;
                   10130:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   10131:          ncovv++; /* Varying variables without age */
                   10132:          TvarV[ncovv]=Tvar[k];
                   10133:          TvarVind[ncovv]=k;
                   10134:        }
1.227     brouard  10135:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  10136:        if(Tvard[k1][2] <=ncovcol){
                   10137:          Fixed[k]= 0;  /* or 2 ?*/
                   10138:          Dummy[k]= 1;
                   10139:          modell[k].maintype= FTYPE;
                   10140:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   10141:          ncovf++; /* Fixed variables without age */
                   10142:          TvarF[ncovf]=Tvar[k];
                   10143:          TvarFind[ncovf]=k;
                   10144:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10145:          Fixed[k]= 1;
                   10146:          Dummy[k]= 1;
                   10147:          modell[k].maintype= VTYPE;
                   10148:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   10149:          ncovv++; /* Varying variables without age */
                   10150:          TvarV[ncovv]=Tvar[k];
                   10151:          TvarVind[ncovv]=k;
                   10152:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10153:          Fixed[k]= 1;
                   10154:          Dummy[k]= 1;
                   10155:          modell[k].maintype= VTYPE;
                   10156:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   10157:          ncovv++; /* Varying variables without age */
                   10158:          TvarV[ncovv]=Tvar[k];
                   10159:          TvarVind[ncovv]=k;
                   10160:          ncovv++; /* Varying variables without age */
                   10161:          TvarV[ncovv]=Tvar[k];
                   10162:          TvarVind[ncovv]=k;
                   10163:        }
1.227     brouard  10164:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  10165:        if(Tvard[k1][2] <=ncovcol){
                   10166:          Fixed[k]= 1;
                   10167:          Dummy[k]= 1;
                   10168:          modell[k].maintype= VTYPE;
                   10169:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   10170:          ncovv++; /* Varying variables without age */
                   10171:          TvarV[ncovv]=Tvar[k];
                   10172:          TvarVind[ncovv]=k;
                   10173:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10174:          Fixed[k]= 1;
                   10175:          Dummy[k]= 1;
                   10176:          modell[k].maintype= VTYPE;
                   10177:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   10178:          ncovv++; /* Varying variables without age */
                   10179:          TvarV[ncovv]=Tvar[k];
                   10180:          TvarVind[ncovv]=k;
                   10181:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10182:          Fixed[k]= 1;
                   10183:          Dummy[k]= 0;
                   10184:          modell[k].maintype= VTYPE;
                   10185:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   10186:          ncovv++; /* Varying variables without age */
                   10187:          TvarV[ncovv]=Tvar[k];
                   10188:          TvarVind[ncovv]=k;
                   10189:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10190:          Fixed[k]= 1;
                   10191:          Dummy[k]= 1;
                   10192:          modell[k].maintype= VTYPE;
                   10193:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   10194:          ncovv++; /* Varying variables without age */
                   10195:          TvarV[ncovv]=Tvar[k];
                   10196:          TvarVind[ncovv]=k;
                   10197:        }
1.227     brouard  10198:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10199:        if(Tvard[k1][2] <=ncovcol){
                   10200:          Fixed[k]= 1;
                   10201:          Dummy[k]= 1;
                   10202:          modell[k].maintype= VTYPE;
                   10203:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   10204:          ncovv++; /* Varying variables without age */
                   10205:          TvarV[ncovv]=Tvar[k];
                   10206:          TvarVind[ncovv]=k;
                   10207:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10208:          Fixed[k]= 1;
                   10209:          Dummy[k]= 1;
                   10210:          modell[k].maintype= VTYPE;
                   10211:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   10212:          ncovv++; /* Varying variables without age */
                   10213:          TvarV[ncovv]=Tvar[k];
                   10214:          TvarVind[ncovv]=k;
                   10215:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10216:          Fixed[k]= 1;
                   10217:          Dummy[k]= 1;
                   10218:          modell[k].maintype= VTYPE;
                   10219:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   10220:          ncovv++; /* Varying variables without age */
                   10221:          TvarV[ncovv]=Tvar[k];
                   10222:          TvarVind[ncovv]=k;
                   10223:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10224:          Fixed[k]= 1;
                   10225:          Dummy[k]= 1;
                   10226:          modell[k].maintype= VTYPE;
                   10227:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10228:          ncovv++; /* Varying variables without age */
                   10229:          TvarV[ncovv]=Tvar[k];
                   10230:          TvarVind[ncovv]=k;
                   10231:        }
1.227     brouard  10232:       }else{
1.240     brouard  10233:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10234:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10235:       } /*end k1*/
1.225     brouard  10236:     }else{
1.226     brouard  10237:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10238:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10239:     }
1.227     brouard  10240:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10241:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10242:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10243:   }
                   10244:   /* Searching for doublons in the model */
                   10245:   for(k1=1; k1<= cptcovt;k1++){
                   10246:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10247:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10248:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10249:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10250:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10251:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10252:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10253:            return(1);
                   10254:          }
                   10255:        }else if (Typevar[k1] ==2){
                   10256:          k3=Tposprod[k1];
                   10257:          k4=Tposprod[k2];
                   10258:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10259:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10260:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10261:            return(1);
                   10262:          }
                   10263:        }
1.227     brouard  10264:       }
                   10265:     }
1.225     brouard  10266:   }
                   10267:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10268:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10269:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10270:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10271:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10272:   /*endread:*/
1.225     brouard  10273:   printf("Exiting decodemodel: ");
                   10274:   return (1);
1.136     brouard  10275: }
                   10276: 
1.169     brouard  10277: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10278: {/* Check ages at death */
1.136     brouard  10279:   int i, m;
1.218     brouard  10280:   int firstone=0;
                   10281:   
1.136     brouard  10282:   for (i=1; i<=imx; i++) {
                   10283:     for(m=2; (m<= maxwav); m++) {
                   10284:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10285:        anint[m][i]=9999;
1.216     brouard  10286:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10287:          s[m][i]=-1;
1.136     brouard  10288:       }
                   10289:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10290:        *nberr = *nberr + 1;
1.218     brouard  10291:        if(firstone == 0){
                   10292:          firstone=1;
1.260     brouard  10293:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10294:        }
1.262     brouard  10295:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10296:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10297:       }
                   10298:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10299:        (*nberr)++;
1.259     brouard  10300:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10301:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10302:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10303:       }
                   10304:     }
                   10305:   }
                   10306: 
                   10307:   for (i=1; i<=imx; i++)  {
                   10308:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10309:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10310:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10311:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10312:          if(agedc[i]>0){
                   10313:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10314:              agev[m][i]=agedc[i];
1.214     brouard  10315:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10316:            }else {
1.136     brouard  10317:              if ((int)andc[i]!=9999){
                   10318:                nbwarn++;
                   10319:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10320:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10321:                agev[m][i]=-1;
                   10322:              }
                   10323:            }
1.169     brouard  10324:          } /* agedc > 0 */
1.214     brouard  10325:        } /* end if */
1.136     brouard  10326:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10327:                                 years but with the precision of a month */
                   10328:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10329:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10330:            agev[m][i]=1;
                   10331:          else if(agev[m][i] < *agemin){ 
                   10332:            *agemin=agev[m][i];
                   10333:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10334:          }
                   10335:          else if(agev[m][i] >*agemax){
                   10336:            *agemax=agev[m][i];
1.156     brouard  10337:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10338:          }
                   10339:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10340:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10341:        } /* en if 9*/
1.136     brouard  10342:        else { /* =9 */
1.214     brouard  10343:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10344:          agev[m][i]=1;
                   10345:          s[m][i]=-1;
                   10346:        }
                   10347:       }
1.214     brouard  10348:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10349:        agev[m][i]=1;
1.214     brouard  10350:       else{
                   10351:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10352:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10353:        agev[m][i]=0;
                   10354:       }
                   10355:     } /* End for lastpass */
                   10356:   }
1.136     brouard  10357:     
                   10358:   for (i=1; i<=imx; i++)  {
                   10359:     for(m=firstpass; (m<=lastpass); m++){
                   10360:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10361:        (*nberr)++;
1.136     brouard  10362:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10363:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10364:        return 1;
                   10365:       }
                   10366:     }
                   10367:   }
                   10368: 
                   10369:   /*for (i=1; i<=imx; i++){
                   10370:   for (m=firstpass; (m<lastpass); m++){
                   10371:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10372: }
                   10373: 
                   10374: }*/
                   10375: 
                   10376: 
1.139     brouard  10377:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10378:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10379: 
                   10380:   return (0);
1.164     brouard  10381:  /* endread:*/
1.136     brouard  10382:     printf("Exiting calandcheckages: ");
                   10383:     return (1);
                   10384: }
                   10385: 
1.172     brouard  10386: #if defined(_MSC_VER)
                   10387: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10388: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10389: //#include "stdafx.h"
                   10390: //#include <stdio.h>
                   10391: //#include <tchar.h>
                   10392: //#include <windows.h>
                   10393: //#include <iostream>
                   10394: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10395: 
                   10396: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10397: 
                   10398: BOOL IsWow64()
                   10399: {
                   10400:        BOOL bIsWow64 = FALSE;
                   10401: 
                   10402:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10403:        //  (HANDLE, PBOOL);
                   10404: 
                   10405:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10406: 
                   10407:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10408:        const char funcName[] = "IsWow64Process";
                   10409:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10410:                GetProcAddress(module, funcName);
                   10411: 
                   10412:        if (NULL != fnIsWow64Process)
                   10413:        {
                   10414:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10415:                        &bIsWow64))
                   10416:                        //throw std::exception("Unknown error");
                   10417:                        printf("Unknown error\n");
                   10418:        }
                   10419:        return bIsWow64 != FALSE;
                   10420: }
                   10421: #endif
1.177     brouard  10422: 
1.191     brouard  10423: void syscompilerinfo(int logged)
1.292     brouard  10424: {
                   10425: #include <stdint.h>
                   10426: 
                   10427:   /* #include "syscompilerinfo.h"*/
1.185     brouard  10428:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10429:    /* /GS /W3 /Gy
                   10430:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10431:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10432:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10433:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10434:    */ 
                   10435:    /* 64 bits */
1.185     brouard  10436:    /*
                   10437:      /GS /W3 /Gy
                   10438:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10439:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10440:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10441:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10442:    /* Optimization are useless and O3 is slower than O2 */
                   10443:    /*
                   10444:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10445:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10446:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10447:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10448:    */
1.186     brouard  10449:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10450:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10451:       /PDB:"visual studio
                   10452:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10453:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10454:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10455:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10456:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10457:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10458:       uiAccess='false'"
                   10459:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10460:       /NOLOGO /TLBID:1
                   10461:    */
1.292     brouard  10462: 
                   10463: 
1.177     brouard  10464: #if defined __INTEL_COMPILER
1.178     brouard  10465: #if defined(__GNUC__)
                   10466:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10467: #endif
1.177     brouard  10468: #elif defined(__GNUC__) 
1.179     brouard  10469: #ifndef  __APPLE__
1.174     brouard  10470: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10471: #endif
1.177     brouard  10472:    struct utsname sysInfo;
1.178     brouard  10473:    int cross = CROSS;
                   10474:    if (cross){
                   10475:           printf("Cross-");
1.191     brouard  10476:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10477:    }
1.174     brouard  10478: #endif
                   10479: 
1.191     brouard  10480:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10481: #if defined(__clang__)
1.191     brouard  10482:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10483: #endif
                   10484: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10485:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10486: #endif
                   10487: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10488:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10489: #endif
                   10490: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10491:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10492: #endif
                   10493: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10494:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10495: #endif
                   10496: #if defined(_MSC_VER)
1.191     brouard  10497:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10498: #endif
                   10499: #if defined(__PGI)
1.191     brouard  10500:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10501: #endif
                   10502: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10503:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10504: #endif
1.191     brouard  10505:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10506:    
1.167     brouard  10507: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10508: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10509:     // Windows (x64 and x86)
1.191     brouard  10510:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10511: #elif __unix__ // all unices, not all compilers
                   10512:     // Unix
1.191     brouard  10513:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10514: #elif __linux__
                   10515:     // linux
1.191     brouard  10516:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10517: #elif __APPLE__
1.174     brouard  10518:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10519:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10520: #endif
                   10521: 
                   10522: /*  __MINGW32__          */
                   10523: /*  __CYGWIN__  */
                   10524: /* __MINGW64__  */
                   10525: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10526: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10527: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10528: /* _WIN64  // Defined for applications for Win64. */
                   10529: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10530: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10531: 
1.167     brouard  10532: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10533:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10534: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10535:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10536: #else
1.191     brouard  10537:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10538: #endif
                   10539: 
1.169     brouard  10540: #if defined(__GNUC__)
                   10541: # if defined(__GNUC_PATCHLEVEL__)
                   10542: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10543:                             + __GNUC_MINOR__ * 100 \
                   10544:                             + __GNUC_PATCHLEVEL__)
                   10545: # else
                   10546: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10547:                             + __GNUC_MINOR__ * 100)
                   10548: # endif
1.174     brouard  10549:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10550:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10551: 
                   10552:    if (uname(&sysInfo) != -1) {
                   10553:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10554:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10555:    }
                   10556:    else
                   10557:       perror("uname() error");
1.179     brouard  10558:    //#ifndef __INTEL_COMPILER 
                   10559: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10560:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10561:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10562: #endif
1.169     brouard  10563: #endif
1.172     brouard  10564: 
1.286     brouard  10565:    //   void main ()
1.172     brouard  10566:    //   {
1.169     brouard  10567: #if defined(_MSC_VER)
1.174     brouard  10568:    if (IsWow64()){
1.191     brouard  10569:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10570:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10571:    }
                   10572:    else{
1.191     brouard  10573:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10574:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10575:    }
1.172     brouard  10576:    //     printf("\nPress Enter to continue...");
                   10577:    //     getchar();
                   10578:    //   }
                   10579: 
1.169     brouard  10580: #endif
                   10581:    
1.167     brouard  10582: 
1.219     brouard  10583: }
1.136     brouard  10584: 
1.219     brouard  10585: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10586:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10587:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10588:   /* double ftolpl = 1.e-10; */
1.180     brouard  10589:   double age, agebase, agelim;
1.203     brouard  10590:   double tot;
1.180     brouard  10591: 
1.202     brouard  10592:   strcpy(filerespl,"PL_");
                   10593:   strcat(filerespl,fileresu);
                   10594:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10595:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10596:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10597:   }
1.288     brouard  10598:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10599:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10600:   pstamp(ficrespl);
1.288     brouard  10601:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10602:   fprintf(ficrespl,"#Age ");
                   10603:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10604:   fprintf(ficrespl,"\n");
1.180     brouard  10605:   
1.219     brouard  10606:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10607: 
1.219     brouard  10608:   agebase=ageminpar;
                   10609:   agelim=agemaxpar;
1.180     brouard  10610: 
1.227     brouard  10611:   /* i1=pow(2,ncoveff); */
1.234     brouard  10612:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10613:   if (cptcovn < 1){i1=1;}
1.180     brouard  10614: 
1.238     brouard  10615:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10616:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10617:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10618:        continue;
1.235     brouard  10619: 
1.238     brouard  10620:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10621:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10622:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10623:       /* k=k+1; */
                   10624:       /* to clean */
                   10625:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10626:       fprintf(ficrespl,"#******");
                   10627:       printf("#******");
                   10628:       fprintf(ficlog,"#******");
                   10629:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10630:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10631:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10632:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10633:       }
                   10634:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10635:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10636:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10637:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10638:       }
                   10639:       fprintf(ficrespl,"******\n");
                   10640:       printf("******\n");
                   10641:       fprintf(ficlog,"******\n");
                   10642:       if(invalidvarcomb[k]){
                   10643:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10644:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10645:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10646:        continue;
                   10647:       }
1.219     brouard  10648: 
1.238     brouard  10649:       fprintf(ficrespl,"#Age ");
                   10650:       for(j=1;j<=cptcoveff;j++) {
                   10651:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10652:       }
                   10653:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10654:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10655:     
1.238     brouard  10656:       for (age=agebase; age<=agelim; age++){
                   10657:        /* for (age=agebase; age<=agebase; age++){ */
                   10658:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10659:        fprintf(ficrespl,"%.0f ",age );
                   10660:        for(j=1;j<=cptcoveff;j++)
                   10661:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10662:        tot=0.;
                   10663:        for(i=1; i<=nlstate;i++){
                   10664:          tot +=  prlim[i][i];
                   10665:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10666:        }
                   10667:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10668:       } /* Age */
                   10669:       /* was end of cptcod */
                   10670:     } /* cptcov */
                   10671:   } /* nres */
1.219     brouard  10672:   return 0;
1.180     brouard  10673: }
                   10674: 
1.218     brouard  10675: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10676:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10677:        
                   10678:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10679:    * at any age between ageminpar and agemaxpar
                   10680:         */
1.235     brouard  10681:   int i, j, k, i1, nres=0 ;
1.217     brouard  10682:   /* double ftolpl = 1.e-10; */
                   10683:   double age, agebase, agelim;
                   10684:   double tot;
1.218     brouard  10685:   /* double ***mobaverage; */
                   10686:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10687: 
                   10688:   strcpy(fileresplb,"PLB_");
                   10689:   strcat(fileresplb,fileresu);
                   10690:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10691:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10692:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10693:   }
1.288     brouard  10694:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10695:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10696:   pstamp(ficresplb);
1.288     brouard  10697:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10698:   fprintf(ficresplb,"#Age ");
                   10699:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10700:   fprintf(ficresplb,"\n");
                   10701:   
1.218     brouard  10702:   
                   10703:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10704:   
                   10705:   agebase=ageminpar;
                   10706:   agelim=agemaxpar;
                   10707:   
                   10708:   
1.227     brouard  10709:   i1=pow(2,cptcoveff);
1.218     brouard  10710:   if (cptcovn < 1){i1=1;}
1.227     brouard  10711:   
1.238     brouard  10712:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10713:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10714:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10715:        continue;
                   10716:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10717:       fprintf(ficresplb,"#******");
                   10718:       printf("#******");
                   10719:       fprintf(ficlog,"#******");
                   10720:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10721:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10722:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10723:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10724:       }
                   10725:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10726:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10727:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10728:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10729:       }
                   10730:       fprintf(ficresplb,"******\n");
                   10731:       printf("******\n");
                   10732:       fprintf(ficlog,"******\n");
                   10733:       if(invalidvarcomb[k]){
                   10734:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10735:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10736:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10737:        continue;
                   10738:       }
1.218     brouard  10739:     
1.238     brouard  10740:       fprintf(ficresplb,"#Age ");
                   10741:       for(j=1;j<=cptcoveff;j++) {
                   10742:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10743:       }
                   10744:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10745:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10746:     
                   10747:     
1.238     brouard  10748:       for (age=agebase; age<=agelim; age++){
                   10749:        /* for (age=agebase; age<=agebase; age++){ */
                   10750:        if(mobilavproj > 0){
                   10751:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10752:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10753:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10754:        }else if (mobilavproj == 0){
                   10755:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10756:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10757:          exit(1);
                   10758:        }else{
                   10759:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10760:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10761:          /* printf("TOTOT\n"); */
                   10762:           /* exit(1); */
1.238     brouard  10763:        }
                   10764:        fprintf(ficresplb,"%.0f ",age );
                   10765:        for(j=1;j<=cptcoveff;j++)
                   10766:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10767:        tot=0.;
                   10768:        for(i=1; i<=nlstate;i++){
                   10769:          tot +=  bprlim[i][i];
                   10770:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10771:        }
                   10772:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10773:       } /* Age */
                   10774:       /* was end of cptcod */
1.255     brouard  10775:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10776:     } /* end of any combination */
                   10777:   } /* end of nres */  
1.218     brouard  10778:   /* hBijx(p, bage, fage); */
                   10779:   /* fclose(ficrespijb); */
                   10780:   
                   10781:   return 0;
1.217     brouard  10782: }
1.218     brouard  10783:  
1.180     brouard  10784: int hPijx(double *p, int bage, int fage){
                   10785:     /*------------- h Pij x at various ages ------------*/
                   10786: 
                   10787:   int stepsize;
                   10788:   int agelim;
                   10789:   int hstepm;
                   10790:   int nhstepm;
1.235     brouard  10791:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10792: 
                   10793:   double agedeb;
                   10794:   double ***p3mat;
                   10795: 
1.201     brouard  10796:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10797:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10798:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10799:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10800:     }
                   10801:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10802:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10803:   
                   10804:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10805:     /*if (stepm<=24) stepsize=2;*/
                   10806: 
                   10807:     agelim=AGESUP;
                   10808:     hstepm=stepsize*YEARM; /* Every year of age */
                   10809:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10810:                
1.180     brouard  10811:     /* hstepm=1;   aff par mois*/
                   10812:     pstamp(ficrespij);
                   10813:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10814:     i1= pow(2,cptcoveff);
1.218     brouard  10815:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10816:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10817:                /*      k=k+1;  */
1.235     brouard  10818:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10819:     for(k=1; k<=i1;k++){
1.253     brouard  10820:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10821:        continue;
1.183     brouard  10822:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10823:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10824:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10825:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10826:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10827:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10828:       }
1.183     brouard  10829:       fprintf(ficrespij,"******\n");
                   10830:       
                   10831:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10832:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10833:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10834:        
                   10835:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10836:        
1.183     brouard  10837:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10838:        oldm=oldms;savm=savms;
1.235     brouard  10839:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10840:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10841:        for(i=1; i<=nlstate;i++)
                   10842:          for(j=1; j<=nlstate+ndeath;j++)
                   10843:            fprintf(ficrespij," %1d-%1d",i,j);
                   10844:        fprintf(ficrespij,"\n");
                   10845:        for (h=0; h<=nhstepm; h++){
                   10846:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10847:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10848:          for(i=1; i<=nlstate;i++)
                   10849:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10850:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10851:          fprintf(ficrespij,"\n");
                   10852:        }
1.183     brouard  10853:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10854:        fprintf(ficrespij,"\n");
                   10855:       }
1.180     brouard  10856:       /*}*/
                   10857:     }
1.218     brouard  10858:     return 0;
1.180     brouard  10859: }
1.218     brouard  10860:  
                   10861:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10862:     /*------------- h Bij x at various ages ------------*/
                   10863: 
                   10864:   int stepsize;
1.218     brouard  10865:   /* int agelim; */
                   10866:        int ageminl;
1.217     brouard  10867:   int hstepm;
                   10868:   int nhstepm;
1.238     brouard  10869:   int h, i, i1, j, k, nres;
1.218     brouard  10870:        
1.217     brouard  10871:   double agedeb;
                   10872:   double ***p3mat;
1.218     brouard  10873:        
                   10874:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10875:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10876:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10877:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10878:   }
                   10879:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10880:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10881:   
                   10882:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10883:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10884:   
1.218     brouard  10885:   /* agelim=AGESUP; */
1.289     brouard  10886:   ageminl=AGEINF; /* was 30 */
1.218     brouard  10887:   hstepm=stepsize*YEARM; /* Every year of age */
                   10888:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10889:   
                   10890:   /* hstepm=1;   aff par mois*/
                   10891:   pstamp(ficrespijb);
1.255     brouard  10892:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10893:   i1= pow(2,cptcoveff);
1.218     brouard  10894:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10895:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10896:   /*   k=k+1;  */
1.238     brouard  10897:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10898:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10899:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10900:        continue;
                   10901:       fprintf(ficrespijb,"\n#****** ");
                   10902:       for(j=1;j<=cptcoveff;j++)
                   10903:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10904:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10905:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10906:       }
                   10907:       fprintf(ficrespijb,"******\n");
1.264     brouard  10908:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10909:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10910:        continue;
                   10911:       }
                   10912:       
                   10913:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10914:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10915:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
1.297     brouard  10916:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm+0.1)-1; /* Typically 20 years = 20*12/6=40 or 55*12/24=27.5-1.1=>27 */
                   10917:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 or 28*/
1.238     brouard  10918:        
                   10919:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10920:        
1.266     brouard  10921:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10922:        /* and memory limitations if stepm is small */
                   10923: 
1.238     brouard  10924:        /* oldm=oldms;savm=savms; */
                   10925:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10926:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10927:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10928:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10929:        for(i=1; i<=nlstate;i++)
                   10930:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10931:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10932:        fprintf(ficrespijb,"\n");
1.238     brouard  10933:        for (h=0; h<=nhstepm; h++){
                   10934:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10935:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10936:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10937:          for(i=1; i<=nlstate;i++)
                   10938:            for(j=1; j<=nlstate+ndeath;j++)
                   10939:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10940:          fprintf(ficrespijb,"\n");
                   10941:        }
                   10942:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10943:        fprintf(ficrespijb,"\n");
                   10944:       } /* end age deb */
                   10945:     } /* end combination */
                   10946:   } /* end nres */
1.218     brouard  10947:   return 0;
                   10948:  } /*  hBijx */
1.217     brouard  10949: 
1.180     brouard  10950: 
1.136     brouard  10951: /***********************************************/
                   10952: /**************** Main Program *****************/
                   10953: /***********************************************/
                   10954: 
                   10955: int main(int argc, char *argv[])
                   10956: {
                   10957: #ifdef GSL
                   10958:   const gsl_multimin_fminimizer_type *T;
                   10959:   size_t iteri = 0, it;
                   10960:   int rval = GSL_CONTINUE;
                   10961:   int status = GSL_SUCCESS;
                   10962:   double ssval;
                   10963: #endif
                   10964:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  10965:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   10966:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  10967:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10968:   int jj, ll, li, lj, lk;
1.136     brouard  10969:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10970:   int num_filled;
1.136     brouard  10971:   int itimes;
                   10972:   int NDIM=2;
                   10973:   int vpopbased=0;
1.235     brouard  10974:   int nres=0;
1.258     brouard  10975:   int endishere=0;
1.277     brouard  10976:   int noffset=0;
1.274     brouard  10977:   int ncurrv=0; /* Temporary variable */
                   10978:   
1.164     brouard  10979:   char ca[32], cb[32];
1.136     brouard  10980:   /*  FILE *fichtm; *//* Html File */
                   10981:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10982:   struct stat info;
1.191     brouard  10983:   double agedeb=0.;
1.194     brouard  10984: 
                   10985:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10986:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10987: 
1.165     brouard  10988:   double fret;
1.191     brouard  10989:   double dum=0.; /* Dummy variable */
1.136     brouard  10990:   double ***p3mat;
1.218     brouard  10991:   /* double ***mobaverage; */
1.164     brouard  10992: 
                   10993:   char line[MAXLINE];
1.197     brouard  10994:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10995: 
1.234     brouard  10996:   char  modeltemp[MAXLINE];
1.230     brouard  10997:   char resultline[MAXLINE];
                   10998:   
1.136     brouard  10999:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  11000:   char *tok, *val; /* pathtot */
1.290     brouard  11001:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  11002:   int c,  h , cpt, c2;
1.191     brouard  11003:   int jl=0;
                   11004:   int i1, j1, jk, stepsize=0;
1.194     brouard  11005:   int count=0;
                   11006: 
1.164     brouard  11007:   int *tab; 
1.136     brouard  11008:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.296     brouard  11009:   /* double anprojd, mprojd, jprojd; /\* For eventual projections *\/ */
                   11010:   /* double anprojf, mprojf, jprojf; */
                   11011:   /* double jintmean,mintmean,aintmean;   */
                   11012:   int prvforecast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11013:   int prvbackcast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11014:   double yrfproj= 10.0; /* Number of years of forward projections */
                   11015:   double yrbproj= 10.0; /* Number of years of backward projections */
                   11016:   int prevbcast=0; /* defined as global for mlikeli and mle, replacing backcast */
1.136     brouard  11017:   int mobilav=0,popforecast=0;
1.191     brouard  11018:   int hstepm=0, nhstepm=0;
1.136     brouard  11019:   int agemortsup;
                   11020:   float  sumlpop=0.;
                   11021:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   11022:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   11023: 
1.191     brouard  11024:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  11025:   double ftolpl=FTOL;
                   11026:   double **prlim;
1.217     brouard  11027:   double **bprlim;
1.136     brouard  11028:   double ***param; /* Matrix of parameters */
1.251     brouard  11029:   double ***paramstart; /* Matrix of starting parameter values */
                   11030:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  11031:   double **matcov; /* Matrix of covariance */
1.203     brouard  11032:   double **hess; /* Hessian matrix */
1.136     brouard  11033:   double ***delti3; /* Scale */
                   11034:   double *delti; /* Scale */
                   11035:   double ***eij, ***vareij;
                   11036:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  11037: 
1.136     brouard  11038:   double *epj, vepp;
1.164     brouard  11039: 
1.273     brouard  11040:   double dateprev1, dateprev2;
1.296     brouard  11041:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0, dateprojd=0, dateprojf=0;
                   11042:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0, datebackd=0, datebackf=0;
                   11043: 
1.217     brouard  11044: 
1.136     brouard  11045:   double **ximort;
1.145     brouard  11046:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  11047:   int *dcwave;
                   11048: 
1.164     brouard  11049:   char z[1]="c";
1.136     brouard  11050: 
                   11051:   /*char  *strt;*/
                   11052:   char strtend[80];
1.126     brouard  11053: 
1.164     brouard  11054: 
1.126     brouard  11055: /*   setlocale (LC_ALL, ""); */
                   11056: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   11057: /*   textdomain (PACKAGE); */
                   11058: /*   setlocale (LC_CTYPE, ""); */
                   11059: /*   setlocale (LC_MESSAGES, ""); */
                   11060: 
                   11061:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  11062:   rstart_time = time(NULL);  
                   11063:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   11064:   start_time = *localtime(&rstart_time);
1.126     brouard  11065:   curr_time=start_time;
1.157     brouard  11066:   /*tml = *localtime(&start_time.tm_sec);*/
                   11067:   /* strcpy(strstart,asctime(&tml)); */
                   11068:   strcpy(strstart,asctime(&start_time));
1.126     brouard  11069: 
                   11070: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  11071: /*  tp.tm_sec = tp.tm_sec +86400; */
                   11072: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  11073: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   11074: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   11075: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  11076: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  11077: /*   strt=asctime(&tmg); */
                   11078: /*   printf("Time(after) =%s",strstart);  */
                   11079: /*  (void) time (&time_value);
                   11080: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   11081: *  tm = *localtime(&time_value);
                   11082: *  strstart=asctime(&tm);
                   11083: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   11084: */
                   11085: 
                   11086:   nberr=0; /* Number of errors and warnings */
                   11087:   nbwarn=0;
1.184     brouard  11088: #ifdef WIN32
                   11089:   _getcwd(pathcd, size);
                   11090: #else
1.126     brouard  11091:   getcwd(pathcd, size);
1.184     brouard  11092: #endif
1.191     brouard  11093:   syscompilerinfo(0);
1.196     brouard  11094:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  11095:   if(argc <=1){
                   11096:     printf("\nEnter the parameter file name: ");
1.205     brouard  11097:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   11098:       printf("ERROR Empty parameter file name\n");
                   11099:       goto end;
                   11100:     }
1.126     brouard  11101:     i=strlen(pathr);
                   11102:     if(pathr[i-1]=='\n')
                   11103:       pathr[i-1]='\0';
1.156     brouard  11104:     i=strlen(pathr);
1.205     brouard  11105:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  11106:       pathr[i-1]='\0';
1.205     brouard  11107:     }
                   11108:     i=strlen(pathr);
                   11109:     if( i==0 ){
                   11110:       printf("ERROR Empty parameter file name\n");
                   11111:       goto end;
                   11112:     }
                   11113:     for (tok = pathr; tok != NULL; ){
1.126     brouard  11114:       printf("Pathr |%s|\n",pathr);
                   11115:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   11116:       printf("val= |%s| pathr=%s\n",val,pathr);
                   11117:       strcpy (pathtot, val);
                   11118:       if(pathr[0] == '\0') break; /* Dirty */
                   11119:     }
                   11120:   }
1.281     brouard  11121:   else if (argc<=2){
                   11122:     strcpy(pathtot,argv[1]);
                   11123:   }
1.126     brouard  11124:   else{
                   11125:     strcpy(pathtot,argv[1]);
1.281     brouard  11126:     strcpy(z,argv[2]);
                   11127:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  11128:   }
                   11129:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   11130:   /*cygwin_split_path(pathtot,path,optionfile);
                   11131:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   11132:   /* cutv(path,optionfile,pathtot,'\\');*/
                   11133: 
                   11134:   /* Split argv[0], imach program to get pathimach */
                   11135:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   11136:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11137:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11138:  /*   strcpy(pathimach,argv[0]); */
                   11139:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   11140:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   11141:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  11142: #ifdef WIN32
                   11143:   _chdir(path); /* Can be a relative path */
                   11144:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   11145: #else
1.126     brouard  11146:   chdir(path); /* Can be a relative path */
1.184     brouard  11147:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   11148: #endif
                   11149:   printf("Current directory %s!\n",pathcd);
1.126     brouard  11150:   strcpy(command,"mkdir ");
                   11151:   strcat(command,optionfilefiname);
                   11152:   if((outcmd=system(command)) != 0){
1.169     brouard  11153:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  11154:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   11155:     /* fclose(ficlog); */
                   11156: /*     exit(1); */
                   11157:   }
                   11158: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   11159: /*     perror("mkdir"); */
                   11160: /*   } */
                   11161: 
                   11162:   /*-------- arguments in the command line --------*/
                   11163: 
1.186     brouard  11164:   /* Main Log file */
1.126     brouard  11165:   strcat(filelog, optionfilefiname);
                   11166:   strcat(filelog,".log");    /* */
                   11167:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   11168:     printf("Problem with logfile %s\n",filelog);
                   11169:     goto end;
                   11170:   }
                   11171:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  11172:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  11173:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   11174:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   11175:  path=%s \n\
                   11176:  optionfile=%s\n\
                   11177:  optionfilext=%s\n\
1.156     brouard  11178:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  11179: 
1.197     brouard  11180:   syscompilerinfo(1);
1.167     brouard  11181: 
1.126     brouard  11182:   printf("Local time (at start):%s",strstart);
                   11183:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   11184:   fflush(ficlog);
                   11185: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  11186: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  11187: 
                   11188:   /* */
                   11189:   strcpy(fileres,"r");
                   11190:   strcat(fileres, optionfilefiname);
1.201     brouard  11191:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  11192:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  11193:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  11194: 
1.186     brouard  11195:   /* Main ---------arguments file --------*/
1.126     brouard  11196: 
                   11197:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  11198:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   11199:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  11200:     fflush(ficlog);
1.149     brouard  11201:     /* goto end; */
                   11202:     exit(70); 
1.126     brouard  11203:   }
                   11204: 
                   11205:   strcpy(filereso,"o");
1.201     brouard  11206:   strcat(filereso,fileresu);
1.126     brouard  11207:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   11208:     printf("Problem with Output resultfile: %s\n", filereso);
                   11209:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   11210:     fflush(ficlog);
                   11211:     goto end;
                   11212:   }
1.278     brouard  11213:       /*-------- Rewriting parameter file ----------*/
                   11214:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   11215:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   11216:   strcat(rfileres,".");    /* */
                   11217:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11218:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   11219:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11220:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   11221:     fflush(ficlog);
                   11222:     goto end;
                   11223:   }
                   11224:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  11225: 
1.278     brouard  11226:                                      
1.126     brouard  11227:   /* Reads comments: lines beginning with '#' */
                   11228:   numlinepar=0;
1.277     brouard  11229:   /* Is it a BOM UTF-8 Windows file? */
                   11230:   /* First parameter line */
1.197     brouard  11231:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  11232:     noffset=0;
                   11233:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   11234:     {
                   11235:       noffset=noffset+3;
                   11236:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11237:     }
1.302     brouard  11238: /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   11239:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
1.277     brouard  11240:     {
                   11241:       noffset=noffset+2;
                   11242:       printf("# File is an UTF16BE BOM file\n");
                   11243:     }
                   11244:     else if( line[0] == 0 && line[1] == 0)
                   11245:     {
                   11246:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11247:        noffset=noffset+4;
                   11248:        printf("# File is an UTF16BE BOM file\n");
                   11249:       }
                   11250:     } else{
                   11251:       ;/*printf(" Not a BOM file\n");*/
                   11252:     }
                   11253:   
1.197     brouard  11254:     /* If line starts with a # it is a comment */
1.277     brouard  11255:     if (line[noffset] == '#') {
1.197     brouard  11256:       numlinepar++;
                   11257:       fputs(line,stdout);
                   11258:       fputs(line,ficparo);
1.278     brouard  11259:       fputs(line,ficres);
1.197     brouard  11260:       fputs(line,ficlog);
                   11261:       continue;
                   11262:     }else
                   11263:       break;
                   11264:   }
                   11265:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11266:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11267:     if (num_filled != 5) {
                   11268:       printf("Should be 5 parameters\n");
1.283     brouard  11269:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11270:     }
1.126     brouard  11271:     numlinepar++;
1.197     brouard  11272:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11273:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11274:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11275:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11276:   }
                   11277:   /* Second parameter line */
                   11278:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11279:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11280:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11281:     if (line[0] == '#') {
                   11282:       numlinepar++;
1.283     brouard  11283:       printf("%s",line);
                   11284:       fprintf(ficres,"%s",line);
                   11285:       fprintf(ficparo,"%s",line);
                   11286:       fprintf(ficlog,"%s",line);
1.197     brouard  11287:       continue;
                   11288:     }else
                   11289:       break;
                   11290:   }
1.223     brouard  11291:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11292:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11293:     if (num_filled != 11) {
                   11294:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11295:       printf("but line=%s\n",line);
1.283     brouard  11296:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11297:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11298:     }
1.286     brouard  11299:     if( lastpass > maxwav){
                   11300:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11301:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11302:       fflush(ficlog);
                   11303:       goto end;
                   11304:     }
                   11305:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11306:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11307:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11308:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11309:   }
1.203     brouard  11310:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11311:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11312:   /* Third parameter line */
                   11313:   while(fgets(line, MAXLINE, ficpar)) {
                   11314:     /* If line starts with a # it is a comment */
                   11315:     if (line[0] == '#') {
                   11316:       numlinepar++;
1.283     brouard  11317:       printf("%s",line);
                   11318:       fprintf(ficres,"%s",line);
                   11319:       fprintf(ficparo,"%s",line);
                   11320:       fprintf(ficlog,"%s",line);
1.197     brouard  11321:       continue;
                   11322:     }else
                   11323:       break;
                   11324:   }
1.201     brouard  11325:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11326:     if (num_filled != 1){
1.302     brouard  11327:       printf("ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
                   11328:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
1.197     brouard  11329:       model[0]='\0';
                   11330:       goto end;
                   11331:     }
                   11332:     else{
                   11333:       if (model[0]=='+'){
                   11334:        for(i=1; i<=strlen(model);i++)
                   11335:          modeltemp[i-1]=model[i];
1.201     brouard  11336:        strcpy(model,modeltemp); 
1.197     brouard  11337:       }
                   11338:     }
1.199     brouard  11339:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11340:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11341:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11342:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11343:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11344:   }
                   11345:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11346:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11347:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11348:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11349:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11350:   fflush(ficlog);
1.190     brouard  11351:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11352:   if(model[0]=='#'){
1.279     brouard  11353:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11354:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11355:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11356:     if(mle != -1){
1.279     brouard  11357:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11358:       exit(1);
                   11359:     }
                   11360:   }
1.126     brouard  11361:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11362:     ungetc(c,ficpar);
                   11363:     fgets(line, MAXLINE, ficpar);
                   11364:     numlinepar++;
1.195     brouard  11365:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11366:       z[0]=line[1];
                   11367:     }
                   11368:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11369:     fputs(line, stdout);
                   11370:     //puts(line);
1.126     brouard  11371:     fputs(line,ficparo);
                   11372:     fputs(line,ficlog);
                   11373:   }
                   11374:   ungetc(c,ficpar);
                   11375: 
                   11376:    
1.290     brouard  11377:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11378:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11379:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11380:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11381:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11382:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11383:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11384:   */
                   11385:   if (strlen(model)>1) 
1.187     brouard  11386:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11387:   else
1.187     brouard  11388:     ncovmodel=2; /* Constant and age */
1.133     brouard  11389:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11390:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11391:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11392:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11393:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11394:     fflush(stdout);
                   11395:     fclose (ficlog);
                   11396:     goto end;
                   11397:   }
1.126     brouard  11398:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11399:   delti=delti3[1][1];
                   11400:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11401:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11402: /* We could also provide initial parameters values giving by simple logistic regression 
                   11403:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11404:       /* for(i=1;i<nlstate;i++){ */
                   11405:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11406:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11407:       /* } */
1.126     brouard  11408:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11409:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11410:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11411:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11412:     fclose (ficparo);
                   11413:     fclose (ficlog);
                   11414:     goto end;
                   11415:     exit(0);
1.220     brouard  11416:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11417:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11418:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11419:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11420:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11421:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11422:     hess=matrix(1,npar,1,npar);
1.220     brouard  11423:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11424:     /* Read guessed parameters */
1.126     brouard  11425:     /* Reads comments: lines beginning with '#' */
                   11426:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11427:       ungetc(c,ficpar);
                   11428:       fgets(line, MAXLINE, ficpar);
                   11429:       numlinepar++;
1.141     brouard  11430:       fputs(line,stdout);
1.126     brouard  11431:       fputs(line,ficparo);
                   11432:       fputs(line,ficlog);
                   11433:     }
                   11434:     ungetc(c,ficpar);
                   11435:     
                   11436:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11437:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11438:     for(i=1; i <=nlstate; i++){
1.234     brouard  11439:       j=0;
1.126     brouard  11440:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11441:        if(jj==i) continue;
                   11442:        j++;
1.292     brouard  11443:        while((c=getc(ficpar))=='#' && c!= EOF){
                   11444:          ungetc(c,ficpar);
                   11445:          fgets(line, MAXLINE, ficpar);
                   11446:          numlinepar++;
                   11447:          fputs(line,stdout);
                   11448:          fputs(line,ficparo);
                   11449:          fputs(line,ficlog);
                   11450:        }
                   11451:        ungetc(c,ficpar);
1.234     brouard  11452:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11453:        if ((i1 != i) || (j1 != jj)){
                   11454:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11455: It might be a problem of design; if ncovcol and the model are correct\n \
                   11456: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11457:          exit(1);
                   11458:        }
                   11459:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11460:        if(mle==1)
                   11461:          printf("%1d%1d",i,jj);
                   11462:        fprintf(ficlog,"%1d%1d",i,jj);
                   11463:        for(k=1; k<=ncovmodel;k++){
                   11464:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11465:          if(mle==1){
                   11466:            printf(" %lf",param[i][j][k]);
                   11467:            fprintf(ficlog," %lf",param[i][j][k]);
                   11468:          }
                   11469:          else
                   11470:            fprintf(ficlog," %lf",param[i][j][k]);
                   11471:          fprintf(ficparo," %lf",param[i][j][k]);
                   11472:        }
                   11473:        fscanf(ficpar,"\n");
                   11474:        numlinepar++;
                   11475:        if(mle==1)
                   11476:          printf("\n");
                   11477:        fprintf(ficlog,"\n");
                   11478:        fprintf(ficparo,"\n");
1.126     brouard  11479:       }
                   11480:     }  
                   11481:     fflush(ficlog);
1.234     brouard  11482:     
1.251     brouard  11483:     /* Reads parameters values */
1.126     brouard  11484:     p=param[1][1];
1.251     brouard  11485:     pstart=paramstart[1][1];
1.126     brouard  11486:     
                   11487:     /* Reads comments: lines beginning with '#' */
                   11488:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11489:       ungetc(c,ficpar);
                   11490:       fgets(line, MAXLINE, ficpar);
                   11491:       numlinepar++;
1.141     brouard  11492:       fputs(line,stdout);
1.126     brouard  11493:       fputs(line,ficparo);
                   11494:       fputs(line,ficlog);
                   11495:     }
                   11496:     ungetc(c,ficpar);
                   11497: 
                   11498:     for(i=1; i <=nlstate; i++){
                   11499:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11500:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11501:        if ( (i1-i) * (j1-j) != 0){
                   11502:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11503:          exit(1);
                   11504:        }
                   11505:        printf("%1d%1d",i,j);
                   11506:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11507:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11508:        for(k=1; k<=ncovmodel;k++){
                   11509:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11510:          printf(" %le",delti3[i][j][k]);
                   11511:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11512:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11513:        }
                   11514:        fscanf(ficpar,"\n");
                   11515:        numlinepar++;
                   11516:        printf("\n");
                   11517:        fprintf(ficparo,"\n");
                   11518:        fprintf(ficlog,"\n");
1.126     brouard  11519:       }
                   11520:     }
                   11521:     fflush(ficlog);
1.234     brouard  11522:     
1.145     brouard  11523:     /* Reads covariance matrix */
1.126     brouard  11524:     delti=delti3[1][1];
1.220     brouard  11525:                
                   11526:                
1.126     brouard  11527:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11528:                
1.126     brouard  11529:     /* Reads comments: lines beginning with '#' */
                   11530:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11531:       ungetc(c,ficpar);
                   11532:       fgets(line, MAXLINE, ficpar);
                   11533:       numlinepar++;
1.141     brouard  11534:       fputs(line,stdout);
1.126     brouard  11535:       fputs(line,ficparo);
                   11536:       fputs(line,ficlog);
                   11537:     }
                   11538:     ungetc(c,ficpar);
1.220     brouard  11539:                
1.126     brouard  11540:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11541:     hess=matrix(1,npar,1,npar);
1.131     brouard  11542:     for(i=1; i <=npar; i++)
                   11543:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11544:                
1.194     brouard  11545:     /* Scans npar lines */
1.126     brouard  11546:     for(i=1; i <=npar; i++){
1.226     brouard  11547:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11548:       if(count != 3){
1.226     brouard  11549:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11550: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11551: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11552:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11553: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11554: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11555:        exit(1);
1.220     brouard  11556:       }else{
1.226     brouard  11557:        if(mle==1)
                   11558:          printf("%1d%1d%d",i1,j1,jk);
                   11559:       }
                   11560:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11561:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11562:       for(j=1; j <=i; j++){
1.226     brouard  11563:        fscanf(ficpar," %le",&matcov[i][j]);
                   11564:        if(mle==1){
                   11565:          printf(" %.5le",matcov[i][j]);
                   11566:        }
                   11567:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11568:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11569:       }
                   11570:       fscanf(ficpar,"\n");
                   11571:       numlinepar++;
                   11572:       if(mle==1)
1.220     brouard  11573:                                printf("\n");
1.126     brouard  11574:       fprintf(ficlog,"\n");
                   11575:       fprintf(ficparo,"\n");
                   11576:     }
1.194     brouard  11577:     /* End of read covariance matrix npar lines */
1.126     brouard  11578:     for(i=1; i <=npar; i++)
                   11579:       for(j=i+1;j<=npar;j++)
1.226     brouard  11580:        matcov[i][j]=matcov[j][i];
1.126     brouard  11581:     
                   11582:     if(mle==1)
                   11583:       printf("\n");
                   11584:     fprintf(ficlog,"\n");
                   11585:     
                   11586:     fflush(ficlog);
                   11587:     
                   11588:   }    /* End of mle != -3 */
1.218     brouard  11589:   
1.186     brouard  11590:   /*  Main data
                   11591:    */
1.290     brouard  11592:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11593:   /* num=lvector(1,n); */
                   11594:   /* moisnais=vector(1,n); */
                   11595:   /* annais=vector(1,n); */
                   11596:   /* moisdc=vector(1,n); */
                   11597:   /* andc=vector(1,n); */
                   11598:   /* weight=vector(1,n); */
                   11599:   /* agedc=vector(1,n); */
                   11600:   /* cod=ivector(1,n); */
                   11601:   /* for(i=1;i<=n;i++){ */
                   11602:   num=lvector(firstobs,lastobs);
                   11603:   moisnais=vector(firstobs,lastobs);
                   11604:   annais=vector(firstobs,lastobs);
                   11605:   moisdc=vector(firstobs,lastobs);
                   11606:   andc=vector(firstobs,lastobs);
                   11607:   weight=vector(firstobs,lastobs);
                   11608:   agedc=vector(firstobs,lastobs);
                   11609:   cod=ivector(firstobs,lastobs);
                   11610:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11611:     num[i]=0;
                   11612:     moisnais[i]=0;
                   11613:     annais[i]=0;
                   11614:     moisdc[i]=0;
                   11615:     andc[i]=0;
                   11616:     agedc[i]=0;
                   11617:     cod[i]=0;
                   11618:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11619:   }
1.290     brouard  11620:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11621:   anint=matrix(1,maxwav,firstobs,lastobs);
                   11622:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11623:   tab=ivector(1,NCOVMAX);
1.144     brouard  11624:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11625:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11626: 
1.136     brouard  11627:   /* Reads data from file datafile */
                   11628:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11629:     goto end;
                   11630: 
                   11631:   /* Calculation of the number of parameters from char model */
1.234     brouard  11632:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11633:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11634:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11635:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11636:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11637:   */
                   11638:   
                   11639:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11640:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11641:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11642:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11643:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11644:   TvarF=ivector(1,NCOVMAX); /*  */
                   11645:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11646:   TvarV=ivector(1,NCOVMAX); /*  */
                   11647:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11648:   TvarA=ivector(1,NCOVMAX); /*  */
                   11649:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11650:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11651:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11652:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11653:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11654:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11655:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11656:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11657:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11658: 
1.230     brouard  11659:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11660:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11661:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11662:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11663:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11664:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11665:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11666:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11667:   */
                   11668:   /* For model-covariate k tells which data-covariate to use but
                   11669:     because this model-covariate is a construction we invent a new column
                   11670:     ncovcol + k1
                   11671:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11672:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11673:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11674:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11675:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11676:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11677:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11678:   */
1.145     brouard  11679:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11680:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11681:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11682:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11683:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11684:                         4 covariates (3 plus signs)
                   11685:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11686:                      */  
1.230     brouard  11687:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11688:                                * individual dummy, fixed or varying:
                   11689:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11690:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11691:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11692:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11693:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11694:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11695:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11696:                                * individual quantitative, fixed or varying:
                   11697:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11698:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11699:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11700: /* Main decodemodel */
                   11701: 
1.187     brouard  11702: 
1.223     brouard  11703:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11704:     goto end;
                   11705: 
1.137     brouard  11706:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11707:     nbwarn++;
                   11708:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11709:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11710:   }
1.136     brouard  11711:     /*  if(mle==1){*/
1.137     brouard  11712:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11713:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11714:   }
                   11715: 
                   11716:     /*-calculation of age at interview from date of interview and age at death -*/
                   11717:   agev=matrix(1,maxwav,1,imx);
                   11718: 
                   11719:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11720:     goto end;
                   11721: 
1.126     brouard  11722: 
1.136     brouard  11723:   agegomp=(int)agemin;
1.290     brouard  11724:   free_vector(moisnais,firstobs,lastobs);
                   11725:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11726:   /* free_matrix(mint,1,maxwav,1,n);
                   11727:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11728:   /* free_vector(moisdc,1,n); */
                   11729:   /* free_vector(andc,1,n); */
1.145     brouard  11730:   /* */
                   11731:   
1.126     brouard  11732:   wav=ivector(1,imx);
1.214     brouard  11733:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11734:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11735:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11736:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11737:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11738:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11739:    
                   11740:   /* Concatenates waves */
1.214     brouard  11741:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11742:      Death is a valid wave (if date is known).
                   11743:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11744:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11745:      and mw[mi+1][i]. dh depends on stepm.
                   11746:   */
                   11747: 
1.126     brouard  11748:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11749:   /* Concatenates waves */
1.145     brouard  11750:  
1.290     brouard  11751:   free_vector(moisdc,firstobs,lastobs);
                   11752:   free_vector(andc,firstobs,lastobs);
1.215     brouard  11753: 
1.126     brouard  11754:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11755:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11756:   ncodemax[1]=1;
1.145     brouard  11757:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11758:   cptcoveff=0;
1.220     brouard  11759:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11760:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11761:   }
                   11762:   
                   11763:   ncovcombmax=pow(2,cptcoveff);
                   11764:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11765:   for(i=1;i<ncovcombmax;i++)
                   11766:     invalidvarcomb[i]=0;
                   11767:   
1.211     brouard  11768:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11769:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11770:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11771:   
1.200     brouard  11772:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11773:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11774:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11775:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11776:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11777:    * (currently 0 or 1) in the data.
                   11778:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11779:    * corresponding modality (h,j).
                   11780:    */
                   11781: 
1.145     brouard  11782:   h=0;
                   11783:   /*if (cptcovn > 0) */
1.126     brouard  11784:   m=pow(2,cptcoveff);
                   11785:  
1.144     brouard  11786:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11787:           * For k=4 covariates, h goes from 1 to m=2**k
                   11788:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11789:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11790:           *     h\k   1     2     3     4
1.143     brouard  11791:           *______________________________  
                   11792:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11793:           *     2     2     1     1     1
                   11794:           *     3 i=2 1     2     1     1
                   11795:           *     4     2     2     1     1
                   11796:           *     5 i=3 1 i=2 1     2     1
                   11797:           *     6     2     1     2     1
                   11798:           *     7 i=4 1     2     2     1
                   11799:           *     8     2     2     2     1
1.197     brouard  11800:           *     9 i=5 1 i=3 1 i=2 1     2
                   11801:           *    10     2     1     1     2
                   11802:           *    11 i=6 1     2     1     2
                   11803:           *    12     2     2     1     2
                   11804:           *    13 i=7 1 i=4 1     2     2    
                   11805:           *    14     2     1     2     2
                   11806:           *    15 i=8 1     2     2     2
                   11807:           *    16     2     2     2     2
1.143     brouard  11808:           */
1.212     brouard  11809:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11810:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11811:      * and the value of each covariate?
                   11812:      * V1=1, V2=1, V3=2, V4=1 ?
                   11813:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11814:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11815:      * In order to get the real value in the data, we use nbcode
                   11816:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11817:      * We are keeping this crazy system in order to be able (in the future?) 
                   11818:      * to have more than 2 values (0 or 1) for a covariate.
                   11819:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11820:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11821:      *              bbbbbbbb
                   11822:      *              76543210     
                   11823:      *   h-1        00000101 (6-1=5)
1.219     brouard  11824:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11825:      *           &
                   11826:      *     1        00000001 (1)
1.219     brouard  11827:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11828:      *          +1= 00000001 =1 
1.211     brouard  11829:      *
                   11830:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11831:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11832:      *    >>k'            11
                   11833:      *          &   00000001
                   11834:      *            = 00000001
                   11835:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11836:      * Reverse h=6 and m=16?
                   11837:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11838:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11839:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11840:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11841:      * V3=decodtabm(14,3,2**4)=2
                   11842:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11843:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11844:      *          &1 000000001
                   11845:      *           = 000000001
                   11846:      *         +1= 000000010 =2
                   11847:      *                  2211
                   11848:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11849:      *                  V3=2
1.220     brouard  11850:                 * codtabm and decodtabm are identical
1.211     brouard  11851:      */
                   11852: 
1.145     brouard  11853: 
                   11854:  free_ivector(Ndum,-1,NCOVMAX);
                   11855: 
                   11856: 
1.126     brouard  11857:     
1.186     brouard  11858:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11859:   strcpy(optionfilegnuplot,optionfilefiname);
                   11860:   if(mle==-3)
1.201     brouard  11861:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11862:   strcat(optionfilegnuplot,".gp");
                   11863: 
                   11864:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11865:     printf("Problem with file %s",optionfilegnuplot);
                   11866:   }
                   11867:   else{
1.204     brouard  11868:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11869:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11870:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11871:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11872:   }
                   11873:   /*  fclose(ficgp);*/
1.186     brouard  11874: 
                   11875: 
                   11876:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11877: 
                   11878:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11879:   if(mle==-3)
1.201     brouard  11880:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11881:   strcat(optionfilehtm,".htm");
                   11882:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11883:     printf("Problem with %s \n",optionfilehtm);
                   11884:     exit(0);
1.126     brouard  11885:   }
                   11886: 
                   11887:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11888:   strcat(optionfilehtmcov,"-cov.htm");
                   11889:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11890:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11891:   }
                   11892:   else{
                   11893:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11894: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11895: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11896:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11897:   }
                   11898: 
1.213     brouard  11899:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11900: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11901: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11902: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11903: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11904: \n\
                   11905: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11906:  <ul><li><h4>Parameter files</h4>\n\
                   11907:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11908:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11909:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11910:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11911:  - Date and time at start: %s</ul>\n",\
                   11912:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11913:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11914:          fileres,fileres,\
                   11915:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11916:   fflush(fichtm);
                   11917: 
                   11918:   strcpy(pathr,path);
                   11919:   strcat(pathr,optionfilefiname);
1.184     brouard  11920: #ifdef WIN32
                   11921:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11922: #else
1.126     brouard  11923:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11924: #endif
                   11925:          
1.126     brouard  11926:   
1.220     brouard  11927:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11928:                 and for any valid combination of covariates
1.126     brouard  11929:      and prints on file fileres'p'. */
1.251     brouard  11930:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11931:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11932: 
                   11933:   fprintf(fichtm,"\n");
1.286     brouard  11934:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  11935:          ftol, stepm);
                   11936:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11937:   ncurrv=1;
                   11938:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11939:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11940:   ncurrv=i;
                   11941:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11942:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  11943:   ncurrv=i;
                   11944:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11945:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  11946:   ncurrv=i;
                   11947:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11948:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11949:           nlstate, ndeath, maxwav, mle, weightopt);
                   11950: 
                   11951:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11952: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11953: 
                   11954:   
                   11955:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11956: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11957: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11958:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11959:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11960:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11961:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11962:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11963:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11964: 
1.126     brouard  11965:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11966:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11967:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11968: 
                   11969:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11970:   /* For mortality only */
1.126     brouard  11971:   if (mle==-3){
1.136     brouard  11972:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11973:     for(i=1;i<=NDIM;i++)
                   11974:       for(j=1;j<=NDIM;j++)
                   11975:        ximort[i][j]=0.;
1.186     brouard  11976:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  11977:     cens=ivector(firstobs,lastobs);
                   11978:     ageexmed=vector(firstobs,lastobs);
                   11979:     agecens=vector(firstobs,lastobs);
                   11980:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  11981:                
1.126     brouard  11982:     for (i=1; i<=imx; i++){
                   11983:       dcwave[i]=-1;
                   11984:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11985:        if (s[m][i]>nlstate) {
                   11986:          dcwave[i]=m;
                   11987:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11988:          break;
                   11989:        }
1.126     brouard  11990:     }
1.226     brouard  11991:     
1.126     brouard  11992:     for (i=1; i<=imx; i++) {
                   11993:       if (wav[i]>0){
1.226     brouard  11994:        ageexmed[i]=agev[mw[1][i]][i];
                   11995:        j=wav[i];
                   11996:        agecens[i]=1.; 
                   11997:        
                   11998:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11999:          agecens[i]=agev[mw[j][i]][i];
                   12000:          cens[i]= 1;
                   12001:        }else if (ageexmed[i]< 1) 
                   12002:          cens[i]= -1;
                   12003:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   12004:          cens[i]=0 ;
1.126     brouard  12005:       }
                   12006:       else cens[i]=-1;
                   12007:     }
                   12008:     
                   12009:     for (i=1;i<=NDIM;i++) {
                   12010:       for (j=1;j<=NDIM;j++)
1.226     brouard  12011:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  12012:     }
                   12013:     
1.302     brouard  12014:     p[1]=0.0268; p[NDIM]=0.083;
                   12015:     /* printf("%lf %lf", p[1], p[2]); */
1.126     brouard  12016:     
                   12017:     
1.136     brouard  12018: #ifdef GSL
                   12019:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  12020: #else
1.126     brouard  12021:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  12022: #endif
1.201     brouard  12023:     strcpy(filerespow,"POW-MORT_"); 
                   12024:     strcat(filerespow,fileresu);
1.126     brouard  12025:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   12026:       printf("Problem with resultfile: %s\n", filerespow);
                   12027:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   12028:     }
1.136     brouard  12029: #ifdef GSL
                   12030:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  12031: #else
1.126     brouard  12032:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  12033: #endif
1.126     brouard  12034:     /*  for (i=1;i<=nlstate;i++)
                   12035:        for(j=1;j<=nlstate+ndeath;j++)
                   12036:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   12037:     */
                   12038:     fprintf(ficrespow,"\n");
1.136     brouard  12039: #ifdef GSL
                   12040:     /* gsl starts here */ 
                   12041:     T = gsl_multimin_fminimizer_nmsimplex;
                   12042:     gsl_multimin_fminimizer *sfm = NULL;
                   12043:     gsl_vector *ss, *x;
                   12044:     gsl_multimin_function minex_func;
                   12045: 
                   12046:     /* Initial vertex size vector */
                   12047:     ss = gsl_vector_alloc (NDIM);
                   12048:     
                   12049:     if (ss == NULL){
                   12050:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   12051:     }
                   12052:     /* Set all step sizes to 1 */
                   12053:     gsl_vector_set_all (ss, 0.001);
                   12054: 
                   12055:     /* Starting point */
1.126     brouard  12056:     
1.136     brouard  12057:     x = gsl_vector_alloc (NDIM);
                   12058:     
                   12059:     if (x == NULL){
                   12060:       gsl_vector_free(ss);
                   12061:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   12062:     }
                   12063:   
                   12064:     /* Initialize method and iterate */
                   12065:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  12066:     /*     gsl_vector_set(x, 0, 0.0268); */
                   12067:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  12068:     gsl_vector_set(x, 0, p[1]);
                   12069:     gsl_vector_set(x, 1, p[2]);
                   12070: 
                   12071:     minex_func.f = &gompertz_f;
                   12072:     minex_func.n = NDIM;
                   12073:     minex_func.params = (void *)&p; /* ??? */
                   12074:     
                   12075:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   12076:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   12077:     
                   12078:     printf("Iterations beginning .....\n\n");
                   12079:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   12080: 
                   12081:     iteri=0;
                   12082:     while (rval == GSL_CONTINUE){
                   12083:       iteri++;
                   12084:       status = gsl_multimin_fminimizer_iterate(sfm);
                   12085:       
                   12086:       if (status) printf("error: %s\n", gsl_strerror (status));
                   12087:       fflush(0);
                   12088:       
                   12089:       if (status) 
                   12090:         break;
                   12091:       
                   12092:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   12093:       ssval = gsl_multimin_fminimizer_size (sfm);
                   12094:       
                   12095:       if (rval == GSL_SUCCESS)
                   12096:         printf ("converged to a local maximum at\n");
                   12097:       
                   12098:       printf("%5d ", iteri);
                   12099:       for (it = 0; it < NDIM; it++){
                   12100:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   12101:       }
                   12102:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   12103:     }
                   12104:     
                   12105:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   12106:     
                   12107:     gsl_vector_free(x); /* initial values */
                   12108:     gsl_vector_free(ss); /* inital step size */
                   12109:     for (it=0; it<NDIM; it++){
                   12110:       p[it+1]=gsl_vector_get(sfm->x,it);
                   12111:       fprintf(ficrespow," %.12lf", p[it]);
                   12112:     }
                   12113:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   12114: #endif
                   12115: #ifdef POWELL
                   12116:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   12117: #endif  
1.126     brouard  12118:     fclose(ficrespow);
                   12119:     
1.203     brouard  12120:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  12121: 
                   12122:     for(i=1; i <=NDIM; i++)
                   12123:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  12124:                                matcov[i][j]=matcov[j][i];
1.126     brouard  12125:     
                   12126:     printf("\nCovariance matrix\n ");
1.203     brouard  12127:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  12128:     for(i=1; i <=NDIM; i++) {
                   12129:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  12130:                                printf("%f ",matcov[i][j]);
                   12131:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  12132:       }
1.203     brouard  12133:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  12134:     }
                   12135:     
                   12136:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  12137:     for (i=1;i<=NDIM;i++) {
1.126     brouard  12138:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  12139:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   12140:     }
1.302     brouard  12141:     lsurv=vector(agegomp,AGESUP);
                   12142:     lpop=vector(agegomp,AGESUP);
                   12143:     tpop=vector(agegomp,AGESUP);
1.126     brouard  12144:     lsurv[agegomp]=100000;
                   12145:     
                   12146:     for (k=agegomp;k<=AGESUP;k++) {
                   12147:       agemortsup=k;
                   12148:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   12149:     }
                   12150:     
                   12151:     for (k=agegomp;k<agemortsup;k++)
                   12152:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   12153:     
                   12154:     for (k=agegomp;k<agemortsup;k++){
                   12155:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   12156:       sumlpop=sumlpop+lpop[k];
                   12157:     }
                   12158:     
                   12159:     tpop[agegomp]=sumlpop;
                   12160:     for (k=agegomp;k<(agemortsup-3);k++){
                   12161:       /*  tpop[k+1]=2;*/
                   12162:       tpop[k+1]=tpop[k]-lpop[k];
                   12163:     }
                   12164:     
                   12165:     
                   12166:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   12167:     for (k=agegomp;k<(agemortsup-2);k++) 
                   12168:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   12169:     
                   12170:     
                   12171:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  12172:                ageminpar=50;
                   12173:                agemaxpar=100;
1.194     brouard  12174:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   12175:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12176: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12177: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   12178:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12179: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12180: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12181:     }else{
                   12182:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   12183:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  12184:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  12185:                }
1.201     brouard  12186:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  12187:                     stepm, weightopt,\
                   12188:                     model,imx,p,matcov,agemortsup);
                   12189:     
1.302     brouard  12190:     free_vector(lsurv,agegomp,AGESUP);
                   12191:     free_vector(lpop,agegomp,AGESUP);
                   12192:     free_vector(tpop,agegomp,AGESUP);
1.220     brouard  12193:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  12194:     free_ivector(dcwave,firstobs,lastobs);
                   12195:     free_vector(agecens,firstobs,lastobs);
                   12196:     free_vector(ageexmed,firstobs,lastobs);
                   12197:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  12198: #ifdef GSL
1.136     brouard  12199: #endif
1.186     brouard  12200:   } /* Endof if mle==-3 mortality only */
1.205     brouard  12201:   /* Standard  */
                   12202:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   12203:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12204:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  12205:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  12206:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12207:     for (k=1; k<=npar;k++)
                   12208:       printf(" %d %8.5f",k,p[k]);
                   12209:     printf("\n");
1.205     brouard  12210:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   12211:       /* mlikeli uses func not funcone */
1.247     brouard  12212:       /* for(i=1;i<nlstate;i++){ */
                   12213:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   12214:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   12215:       /* } */
1.205     brouard  12216:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   12217:     }
                   12218:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   12219:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12220:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   12221:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12222:     }
                   12223:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  12224:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12225:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12226:     for (k=1; k<=npar;k++)
                   12227:       printf(" %d %8.5f",k,p[k]);
                   12228:     printf("\n");
                   12229:     
                   12230:     /*--------- results files --------------*/
1.283     brouard  12231:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  12232:     
                   12233:     
                   12234:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12235:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12236:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12237:     for(i=1,jk=1; i <=nlstate; i++){
                   12238:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  12239:        if (k != i) {
                   12240:          printf("%d%d ",i,k);
                   12241:          fprintf(ficlog,"%d%d ",i,k);
                   12242:          fprintf(ficres,"%1d%1d ",i,k);
                   12243:          for(j=1; j <=ncovmodel; j++){
                   12244:            printf("%12.7f ",p[jk]);
                   12245:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12246:            fprintf(ficres,"%12.7f ",p[jk]);
                   12247:            jk++; 
                   12248:          }
                   12249:          printf("\n");
                   12250:          fprintf(ficlog,"\n");
                   12251:          fprintf(ficres,"\n");
                   12252:        }
1.126     brouard  12253:       }
                   12254:     }
1.203     brouard  12255:     if(mle != 0){
                   12256:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12257:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12258:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12259:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12260:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12261:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12262:        for(k=1; k <=(nlstate+ndeath); k++){
                   12263:          if (k != i) {
                   12264:            printf("%d%d ",i,k);
                   12265:            fprintf(ficlog,"%d%d ",i,k);
                   12266:            for(j=1; j <=ncovmodel; j++){
                   12267:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12268:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12269:              jk++; 
                   12270:            }
                   12271:            printf("\n");
                   12272:            fprintf(ficlog,"\n");
                   12273:          }
                   12274:        }
1.193     brouard  12275:       }
1.203     brouard  12276:     } /* end of hesscov and Wald tests */
1.225     brouard  12277:     
1.203     brouard  12278:     /*  */
1.126     brouard  12279:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12280:     printf("# Scales (for hessian or gradient estimation)\n");
                   12281:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12282:     for(i=1,jk=1; i <=nlstate; i++){
                   12283:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12284:        if (j!=i) {
                   12285:          fprintf(ficres,"%1d%1d",i,j);
                   12286:          printf("%1d%1d",i,j);
                   12287:          fprintf(ficlog,"%1d%1d",i,j);
                   12288:          for(k=1; k<=ncovmodel;k++){
                   12289:            printf(" %.5e",delti[jk]);
                   12290:            fprintf(ficlog," %.5e",delti[jk]);
                   12291:            fprintf(ficres," %.5e",delti[jk]);
                   12292:            jk++;
                   12293:          }
                   12294:          printf("\n");
                   12295:          fprintf(ficlog,"\n");
                   12296:          fprintf(ficres,"\n");
                   12297:        }
1.126     brouard  12298:       }
                   12299:     }
                   12300:     
                   12301:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12302:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12303:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12304:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12305:     /* # 121 Var(a12)\n\ */
                   12306:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12307:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12308:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12309:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12310:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12311:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12312:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12313:     
                   12314:     
                   12315:     /* Just to have a covariance matrix which will be more understandable
                   12316:        even is we still don't want to manage dictionary of variables
                   12317:     */
                   12318:     for(itimes=1;itimes<=2;itimes++){
                   12319:       jj=0;
                   12320:       for(i=1; i <=nlstate; i++){
1.225     brouard  12321:        for(j=1; j <=nlstate+ndeath; j++){
                   12322:          if(j==i) continue;
                   12323:          for(k=1; k<=ncovmodel;k++){
                   12324:            jj++;
                   12325:            ca[0]= k+'a'-1;ca[1]='\0';
                   12326:            if(itimes==1){
                   12327:              if(mle>=1)
                   12328:                printf("#%1d%1d%d",i,j,k);
                   12329:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12330:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12331:            }else{
                   12332:              if(mle>=1)
                   12333:                printf("%1d%1d%d",i,j,k);
                   12334:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12335:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12336:            }
                   12337:            ll=0;
                   12338:            for(li=1;li <=nlstate; li++){
                   12339:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12340:                if(lj==li) continue;
                   12341:                for(lk=1;lk<=ncovmodel;lk++){
                   12342:                  ll++;
                   12343:                  if(ll<=jj){
                   12344:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12345:                    if(ll<jj){
                   12346:                      if(itimes==1){
                   12347:                        if(mle>=1)
                   12348:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12349:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12350:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12351:                      }else{
                   12352:                        if(mle>=1)
                   12353:                          printf(" %.5e",matcov[jj][ll]); 
                   12354:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12355:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12356:                      }
                   12357:                    }else{
                   12358:                      if(itimes==1){
                   12359:                        if(mle>=1)
                   12360:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12361:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12362:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12363:                      }else{
                   12364:                        if(mle>=1)
                   12365:                          printf(" %.7e",matcov[jj][ll]); 
                   12366:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12367:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12368:                      }
                   12369:                    }
                   12370:                  }
                   12371:                } /* end lk */
                   12372:              } /* end lj */
                   12373:            } /* end li */
                   12374:            if(mle>=1)
                   12375:              printf("\n");
                   12376:            fprintf(ficlog,"\n");
                   12377:            fprintf(ficres,"\n");
                   12378:            numlinepar++;
                   12379:          } /* end k*/
                   12380:        } /*end j */
1.126     brouard  12381:       } /* end i */
                   12382:     } /* end itimes */
                   12383:     
                   12384:     fflush(ficlog);
                   12385:     fflush(ficres);
1.225     brouard  12386:     while(fgets(line, MAXLINE, ficpar)) {
                   12387:       /* If line starts with a # it is a comment */
                   12388:       if (line[0] == '#') {
                   12389:        numlinepar++;
                   12390:        fputs(line,stdout);
                   12391:        fputs(line,ficparo);
                   12392:        fputs(line,ficlog);
1.299     brouard  12393:        fputs(line,ficres);
1.225     brouard  12394:        continue;
                   12395:       }else
                   12396:        break;
                   12397:     }
                   12398:     
1.209     brouard  12399:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12400:     /*   ungetc(c,ficpar); */
                   12401:     /*   fgets(line, MAXLINE, ficpar); */
                   12402:     /*   fputs(line,stdout); */
                   12403:     /*   fputs(line,ficparo); */
                   12404:     /* } */
                   12405:     /* ungetc(c,ficpar); */
1.126     brouard  12406:     
                   12407:     estepm=0;
1.209     brouard  12408:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12409:       
                   12410:       if (num_filled != 6) {
                   12411:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12412:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12413:        goto end;
                   12414:       }
                   12415:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12416:     }
                   12417:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12418:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12419:     
1.209     brouard  12420:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12421:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12422:     if (fage <= 2) {
                   12423:       bage = ageminpar;
                   12424:       fage = agemaxpar;
                   12425:     }
                   12426:     
                   12427:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12428:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12429:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12430:                
1.186     brouard  12431:     /* Other stuffs, more or less useful */    
1.254     brouard  12432:     while(fgets(line, MAXLINE, ficpar)) {
                   12433:       /* If line starts with a # it is a comment */
                   12434:       if (line[0] == '#') {
                   12435:        numlinepar++;
                   12436:        fputs(line,stdout);
                   12437:        fputs(line,ficparo);
                   12438:        fputs(line,ficlog);
1.299     brouard  12439:        fputs(line,ficres);
1.254     brouard  12440:        continue;
                   12441:       }else
                   12442:        break;
                   12443:     }
                   12444: 
                   12445:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12446:       
                   12447:       if (num_filled != 7) {
                   12448:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12449:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12450:        goto end;
                   12451:       }
                   12452:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12453:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12454:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12455:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12456:     }
1.254     brouard  12457: 
                   12458:     while(fgets(line, MAXLINE, ficpar)) {
                   12459:       /* If line starts with a # it is a comment */
                   12460:       if (line[0] == '#') {
                   12461:        numlinepar++;
                   12462:        fputs(line,stdout);
                   12463:        fputs(line,ficparo);
                   12464:        fputs(line,ficlog);
1.299     brouard  12465:        fputs(line,ficres);
1.254     brouard  12466:        continue;
                   12467:       }else
                   12468:        break;
1.126     brouard  12469:     }
                   12470:     
                   12471:     
                   12472:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12473:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12474:     
1.254     brouard  12475:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12476:       if (num_filled != 1) {
                   12477:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12478:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12479:        goto end;
                   12480:       }
                   12481:       printf("pop_based=%d\n",popbased);
                   12482:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12483:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12484:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12485:     }
                   12486:      
1.258     brouard  12487:     /* Results */
1.307     brouard  12488:     endishere=0;
1.258     brouard  12489:     nresult=0;
1.308     brouard  12490:     parameterline=0;
1.258     brouard  12491:     do{
                   12492:       if(!fgets(line, MAXLINE, ficpar)){
                   12493:        endishere=1;
1.308     brouard  12494:        parameterline=15;
1.258     brouard  12495:       }else if (line[0] == '#') {
                   12496:        /* If line starts with a # it is a comment */
1.254     brouard  12497:        numlinepar++;
                   12498:        fputs(line,stdout);
                   12499:        fputs(line,ficparo);
                   12500:        fputs(line,ficlog);
1.299     brouard  12501:        fputs(line,ficres);
1.254     brouard  12502:        continue;
1.258     brouard  12503:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12504:        parameterline=11;
1.296     brouard  12505:       else if(sscanf(line,"prevbackcast=%[^\n]\n",modeltemp))
1.258     brouard  12506:        parameterline=12;
1.307     brouard  12507:       else if(sscanf(line,"result:%[^\n]\n",modeltemp)){
1.258     brouard  12508:        parameterline=13;
1.307     brouard  12509:       }
1.258     brouard  12510:       else{
                   12511:        parameterline=14;
1.254     brouard  12512:       }
1.308     brouard  12513:       switch (parameterline){ /* =0 only if only comments */
1.258     brouard  12514:       case 11:
1.296     brouard  12515:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12516:                  fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.258     brouard  12517:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12518:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12519:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12520:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12521:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12522:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
1.296     brouard  12523:           prvforecast = 1;
                   12524:        } 
                   12525:        else if((num_filled=sscanf(line,"prevforecast=%d yearsfproj=%lf mobil_average=%d\n",&prevfcast,&yrfproj,&mobilavproj)) !=EOF){/* && (num_filled == 3))*/
1.313     brouard  12526:          printf("prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12527:          fprintf(ficlog,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12528:          fprintf(ficres,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
1.296     brouard  12529:           prvforecast = 2;
                   12530:        }
                   12531:        else {
                   12532:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearsfproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12533:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12534:          goto end;
1.258     brouard  12535:        }
1.254     brouard  12536:        break;
1.258     brouard  12537:       case 12:
1.296     brouard  12538:        if((num_filled=sscanf(line,"prevbackcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&prevbcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12539:           fprintf(ficparo,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12540:          printf("prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12541:          fprintf(ficlog,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12542:          fprintf(ficres,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12543:          /* day and month of back2 are not used but only year anback2.*/
1.273     brouard  12544:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12545:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.296     brouard  12546:           prvbackcast = 1;
                   12547:        } 
                   12548:        else if((num_filled=sscanf(line,"prevbackcast=%d yearsbproj=%lf mobil_average=%d\n",&prevbcast,&yrbproj,&mobilavproj)) ==3){/* && (num_filled == 3))*/
1.313     brouard  12549:          printf("prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12550:          fprintf(ficlog,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12551:          fprintf(ficres,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
1.296     brouard  12552:           prvbackcast = 2;
                   12553:        }
                   12554:        else {
                   12555:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearsbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12556:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12557:          goto end;
1.258     brouard  12558:        }
1.230     brouard  12559:        break;
1.258     brouard  12560:       case 13:
1.307     brouard  12561:        num_filled=sscanf(line,"result:%[^\n]\n",resultline);
                   12562:        nresult++; /* Sum of resultlines */
                   12563:        printf("Result %d: result:%s\n",nresult, resultline);
                   12564:        if(nresult > MAXRESULTLINES){
                   12565:          printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINES,nresult,rfileres);
                   12566:          fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINES,nresult,rfileres);
                   12567:          goto end;
                   12568:        }
1.310     brouard  12569:        if(!decoderesult(resultline, nresult)){ /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.314   ! brouard  12570:          fprintf(ficparo,"result: %s\n",resultline);
        !          12571:          fprintf(ficres,"result: %s\n",resultline);
        !          12572:          fprintf(ficlog,"result: %s\n",resultline);
1.310     brouard  12573:        } else
                   12574:          goto end;
1.307     brouard  12575:        break;
                   12576:       case 14:
                   12577:        printf("Error: Unknown command '%s'\n",line);
                   12578:        fprintf(ficlog,"Error: Unknown command '%s'\n",line);
1.314   ! brouard  12579:        if(line[0] == ' ' || line[0] == '\n'){
        !          12580:          printf("It should not be an empty line '%s'\n",line);
        !          12581:          fprintf(ficlog,"It should not be an empty line '%s'\n",line);
        !          12582:        }         
1.307     brouard  12583:        if(ncovmodel >=2 && nresult==0 ){
                   12584:          printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
                   12585:          fprintf(ficlog,"ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12586:        }
1.307     brouard  12587:        /* goto end; */
                   12588:        break;
1.308     brouard  12589:       case 15:
                   12590:        printf("End of resultlines.\n");
                   12591:        fprintf(ficlog,"End of resultlines.\n");
                   12592:        break;
                   12593:       default: /* parameterline =0 */
1.307     brouard  12594:        nresult=1;
                   12595:        decoderesult(".",nresult ); /* No covariate */
1.258     brouard  12596:       } /* End switch parameterline */
                   12597:     }while(endishere==0); /* End do */
1.126     brouard  12598:     
1.230     brouard  12599:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12600:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12601:     
                   12602:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12603:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12604:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12605: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12606: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12607:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12608: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12609: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12610:     }else{
1.270     brouard  12611:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
1.296     brouard  12612:       /* It seems that anprojd which is computed from the mean year at interview which is known yet because of freqsummary */
                   12613:       /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */ /* Done in freqsummary */
                   12614:       if(prvforecast==1){
                   12615:         dateprojd=(jproj1+12*mproj1+365*anproj1)/365;
                   12616:         jprojd=jproj1;
                   12617:         mprojd=mproj1;
                   12618:         anprojd=anproj1;
                   12619:         dateprojf=(jproj2+12*mproj2+365*anproj2)/365;
                   12620:         jprojf=jproj2;
                   12621:         mprojf=mproj2;
                   12622:         anprojf=anproj2;
                   12623:       } else if(prvforecast == 2){
                   12624:         dateprojd=dateintmean;
                   12625:         date2dmy(dateprojd,&jprojd, &mprojd, &anprojd);
                   12626:         dateprojf=dateintmean+yrfproj;
                   12627:         date2dmy(dateprojf,&jprojf, &mprojf, &anprojf);
                   12628:       }
                   12629:       if(prvbackcast==1){
                   12630:         datebackd=(jback1+12*mback1+365*anback1)/365;
                   12631:         jbackd=jback1;
                   12632:         mbackd=mback1;
                   12633:         anbackd=anback1;
                   12634:         datebackf=(jback2+12*mback2+365*anback2)/365;
                   12635:         jbackf=jback2;
                   12636:         mbackf=mback2;
                   12637:         anbackf=anback2;
                   12638:       } else if(prvbackcast == 2){
                   12639:         datebackd=dateintmean;
                   12640:         date2dmy(datebackd,&jbackd, &mbackd, &anbackd);
                   12641:         datebackf=dateintmean-yrbproj;
                   12642:         date2dmy(datebackf,&jbackf, &mbackf, &anbackf);
                   12643:       }
                   12644:       
                   12645:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, prevbcast, pathc,p, (int)anprojd-bage, (int)anbackd-fage);
1.220     brouard  12646:     }
                   12647:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.296     brouard  12648:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,prevbcast, estepm, \
                   12649:                 jprev1,mprev1,anprev1,dateprev1, dateprojd, datebackd,jprev2,mprev2,anprev2,dateprev2,dateprojf, datebackf);
1.220     brouard  12650:                
1.225     brouard  12651:     /*------------ free_vector  -------------*/
                   12652:     /*  chdir(path); */
1.220     brouard  12653:                
1.215     brouard  12654:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12655:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12656:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12657:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  12658:     free_lvector(num,firstobs,lastobs);
                   12659:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  12660:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12661:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12662:     fclose(ficparo);
                   12663:     fclose(ficres);
1.220     brouard  12664:                
                   12665:                
1.186     brouard  12666:     /* Other results (useful)*/
1.220     brouard  12667:                
                   12668:                
1.126     brouard  12669:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12670:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12671:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12672:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12673:     fclose(ficrespl);
                   12674: 
                   12675:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12676:     /*#include "hpijx.h"*/
                   12677:     hPijx(p, bage, fage);
1.145     brouard  12678:     fclose(ficrespij);
1.227     brouard  12679:     
1.220     brouard  12680:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12681:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12682:     k=1;
1.126     brouard  12683:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12684:     
1.269     brouard  12685:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12686:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12687:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12688:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12689:        for(k=1;k<=ncovcombmax;k++)
                   12690:          probs[i][j][k]=0.;
1.269     brouard  12691:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12692:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12693:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12694:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12695:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12696:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12697:          for(k=1;k<=ncovcombmax;k++)
                   12698:            mobaverages[i][j][k]=0.;
1.219     brouard  12699:       mobaverage=mobaverages;
                   12700:       if (mobilav!=0) {
1.235     brouard  12701:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12702:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12703:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12704:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12705:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12706:        }
1.269     brouard  12707:       } else if (mobilavproj !=0) {
1.235     brouard  12708:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12709:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12710:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12711:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12712:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12713:        }
1.269     brouard  12714:       }else{
                   12715:        printf("Internal error moving average\n");
                   12716:        fflush(stdout);
                   12717:        exit(1);
1.219     brouard  12718:       }
                   12719:     }/* end if moving average */
1.227     brouard  12720:     
1.126     brouard  12721:     /*---------- Forecasting ------------------*/
1.296     brouard  12722:     if(prevfcast==1){ 
                   12723:       /*   /\*    if(stepm ==1){*\/ */
                   12724:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12725:       /*This done previously after freqsummary.*/
                   12726:       /*   dateprojd=(jproj1+12*mproj1+365*anproj1)/365; */
                   12727:       /*   dateprojf=(jproj2+12*mproj2+365*anproj2)/365; */
                   12728:       
                   12729:       /* } else if (prvforecast==2){ */
                   12730:       /*   /\*    if(stepm ==1){*\/ */
                   12731:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12732:       /* } */
                   12733:       /*prevforecast(fileresu, dateintmean, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);*/
                   12734:       prevforecast(fileresu,dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, p, cptcoveff);
1.126     brouard  12735:     }
1.269     brouard  12736: 
1.296     brouard  12737:     /* Prevbcasting */
                   12738:     if(prevbcast==1){
1.219     brouard  12739:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12740:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12741:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12742: 
                   12743:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12744: 
                   12745:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12746: 
1.219     brouard  12747:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12748:       fclose(ficresplb);
                   12749: 
1.222     brouard  12750:       hBijx(p, bage, fage, mobaverage);
                   12751:       fclose(ficrespijb);
1.219     brouard  12752: 
1.296     brouard  12753:       /* /\* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, *\/ */
                   12754:       /* /\*                  mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); *\/ */
                   12755:       /* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, */
                   12756:       /*                      mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
                   12757:       prevbackforecast(fileresu, mobaverage, dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2,
                   12758:                       mobilavproj, bage, fage, firstpass, lastpass, p, cptcoveff);
                   12759: 
                   12760:       
1.269     brouard  12761:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12762: 
                   12763:       
1.269     brouard  12764:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12765:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12766:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12767:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.296     brouard  12768:     }    /* end  Prevbcasting */
1.268     brouard  12769:  
1.186     brouard  12770:  
                   12771:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12772: 
1.215     brouard  12773:     free_ivector(wav,1,imx);
                   12774:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12775:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12776:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12777:                
                   12778:                
1.127     brouard  12779:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12780:                
1.201     brouard  12781:     strcpy(filerese,"E_");
                   12782:     strcat(filerese,fileresu);
1.126     brouard  12783:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12784:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12785:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12786:     }
1.208     brouard  12787:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12788:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12789: 
                   12790:     pstamp(ficreseij);
1.219     brouard  12791:                
1.235     brouard  12792:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12793:     if (cptcovn < 1){i1=1;}
                   12794:     
                   12795:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12796:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12797:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12798:        continue;
1.219     brouard  12799:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12800:       printf("\n#****** ");
1.225     brouard  12801:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12802:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12803:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12804:       }
                   12805:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12806:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12807:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12808:       }
                   12809:       fprintf(ficreseij,"******\n");
1.235     brouard  12810:       printf("******\n");
1.219     brouard  12811:       
                   12812:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12813:       oldm=oldms;savm=savms;
1.235     brouard  12814:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12815:       
1.219     brouard  12816:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12817:     }
                   12818:     fclose(ficreseij);
1.208     brouard  12819:     printf("done evsij\n");fflush(stdout);
                   12820:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12821: 
1.218     brouard  12822:                
1.227     brouard  12823:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12824:                
1.201     brouard  12825:     strcpy(filerest,"T_");
                   12826:     strcat(filerest,fileresu);
1.127     brouard  12827:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12828:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12829:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12830:     }
1.208     brouard  12831:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12832:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12833:     strcpy(fileresstde,"STDE_");
                   12834:     strcat(fileresstde,fileresu);
1.126     brouard  12835:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12836:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12837:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12838:     }
1.227     brouard  12839:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12840:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12841: 
1.201     brouard  12842:     strcpy(filerescve,"CVE_");
                   12843:     strcat(filerescve,fileresu);
1.126     brouard  12844:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12845:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12846:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12847:     }
1.227     brouard  12848:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12849:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12850: 
1.201     brouard  12851:     strcpy(fileresv,"V_");
                   12852:     strcat(fileresv,fileresu);
1.126     brouard  12853:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12854:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12855:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12856:     }
1.227     brouard  12857:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12858:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12859: 
1.235     brouard  12860:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12861:     if (cptcovn < 1){i1=1;}
                   12862:     
                   12863:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12864:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12865:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12866:        continue;
1.242     brouard  12867:       printf("\n#****** Result for:");
                   12868:       fprintf(ficrest,"\n#****** Result for:");
                   12869:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12870:       for(j=1;j<=cptcoveff;j++){ 
                   12871:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12872:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12873:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12874:       }
1.235     brouard  12875:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12876:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12877:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12878:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12879:       }        
1.208     brouard  12880:       fprintf(ficrest,"******\n");
1.227     brouard  12881:       fprintf(ficlog,"******\n");
                   12882:       printf("******\n");
1.208     brouard  12883:       
                   12884:       fprintf(ficresstdeij,"\n#****** ");
                   12885:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12886:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12887:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12888:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12889:       }
1.235     brouard  12890:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12891:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12892:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12893:       }        
1.208     brouard  12894:       fprintf(ficresstdeij,"******\n");
                   12895:       fprintf(ficrescveij,"******\n");
                   12896:       
                   12897:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12898:       /* pstamp(ficresvij); */
1.225     brouard  12899:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12900:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12901:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12902:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12903:       }        
1.208     brouard  12904:       fprintf(ficresvij,"******\n");
                   12905:       
                   12906:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12907:       oldm=oldms;savm=savms;
1.235     brouard  12908:       printf(" cvevsij ");
                   12909:       fprintf(ficlog, " cvevsij ");
                   12910:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12911:       printf(" end cvevsij \n ");
                   12912:       fprintf(ficlog, " end cvevsij \n ");
                   12913:       
                   12914:       /*
                   12915:        */
                   12916:       /* goto endfree; */
                   12917:       
                   12918:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12919:       pstamp(ficrest);
                   12920:       
1.269     brouard  12921:       epj=vector(1,nlstate+1);
1.208     brouard  12922:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12923:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12924:        cptcod= 0; /* To be deleted */
                   12925:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12926:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12927:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12928:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12929:        if(vpopbased==1)
                   12930:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12931:        else
1.288     brouard  12932:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12933:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12934:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12935:        fprintf(ficrest,"\n");
                   12936:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  12937:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   12938:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12939:        for(age=bage; age <=fage ;age++){
1.235     brouard  12940:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12941:          if (vpopbased==1) {
                   12942:            if(mobilav ==0){
                   12943:              for(i=1; i<=nlstate;i++)
                   12944:                prlim[i][i]=probs[(int)age][i][k];
                   12945:            }else{ /* mobilav */ 
                   12946:              for(i=1; i<=nlstate;i++)
                   12947:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12948:            }
                   12949:          }
1.219     brouard  12950:          
1.227     brouard  12951:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12952:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12953:          /* printf(" age %4.0f ",age); */
                   12954:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12955:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12956:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12957:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12958:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12959:            }
                   12960:            epj[nlstate+1] +=epj[j];
                   12961:          }
                   12962:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12963:          
1.227     brouard  12964:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12965:            for(j=1;j <=nlstate;j++)
                   12966:              vepp += vareij[i][j][(int)age];
                   12967:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12968:          for(j=1;j <=nlstate;j++){
                   12969:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12970:          }
                   12971:          fprintf(ficrest,"\n");
                   12972:        }
1.208     brouard  12973:       } /* End vpopbased */
1.269     brouard  12974:       free_vector(epj,1,nlstate+1);
1.208     brouard  12975:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12976:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12977:       printf("done selection\n");fflush(stdout);
                   12978:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12979:       
1.235     brouard  12980:     } /* End k selection */
1.227     brouard  12981: 
                   12982:     printf("done State-specific expectancies\n");fflush(stdout);
                   12983:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12984: 
1.288     brouard  12985:     /* variance-covariance of forward period prevalence*/
1.269     brouard  12986:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12987: 
1.227     brouard  12988:     
1.290     brouard  12989:     free_vector(weight,firstobs,lastobs);
1.227     brouard  12990:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  12991:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   12992:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   12993:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   12994:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  12995:     free_ivector(tab,1,NCOVMAX);
                   12996:     fclose(ficresstdeij);
                   12997:     fclose(ficrescveij);
                   12998:     fclose(ficresvij);
                   12999:     fclose(ficrest);
                   13000:     fclose(ficpar);
                   13001:     
                   13002:     
1.126     brouard  13003:     /*---------- End : free ----------------*/
1.219     brouard  13004:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  13005:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   13006:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  13007:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   13008:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  13009:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  13010:   /* endfree:*/
                   13011:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   13012:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   13013:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  13014:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   13015:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   13016:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   13017:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  13018:   free_matrix(matcov,1,npar,1,npar);
                   13019:   free_matrix(hess,1,npar,1,npar);
                   13020:   /*free_vector(delti,1,npar);*/
                   13021:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   13022:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  13023:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  13024:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   13025:   
                   13026:   free_ivector(ncodemax,1,NCOVMAX);
                   13027:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   13028:   free_ivector(Dummy,-1,NCOVMAX);
                   13029:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  13030:   free_ivector(DummyV,1,NCOVMAX);
                   13031:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  13032:   free_ivector(Typevar,-1,NCOVMAX);
                   13033:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  13034:   free_ivector(TvarsQ,1,NCOVMAX);
                   13035:   free_ivector(TvarsQind,1,NCOVMAX);
                   13036:   free_ivector(TvarsD,1,NCOVMAX);
                   13037:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  13038:   free_ivector(TvarFD,1,NCOVMAX);
                   13039:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  13040:   free_ivector(TvarF,1,NCOVMAX);
                   13041:   free_ivector(TvarFind,1,NCOVMAX);
                   13042:   free_ivector(TvarV,1,NCOVMAX);
                   13043:   free_ivector(TvarVind,1,NCOVMAX);
                   13044:   free_ivector(TvarA,1,NCOVMAX);
                   13045:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  13046:   free_ivector(TvarFQ,1,NCOVMAX);
                   13047:   free_ivector(TvarFQind,1,NCOVMAX);
                   13048:   free_ivector(TvarVD,1,NCOVMAX);
                   13049:   free_ivector(TvarVDind,1,NCOVMAX);
                   13050:   free_ivector(TvarVQ,1,NCOVMAX);
                   13051:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  13052:   free_ivector(Tvarsel,1,NCOVMAX);
                   13053:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  13054:   free_ivector(Tposprod,1,NCOVMAX);
                   13055:   free_ivector(Tprod,1,NCOVMAX);
                   13056:   free_ivector(Tvaraff,1,NCOVMAX);
                   13057:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   13058:   free_ivector(Tage,1,NCOVMAX);
                   13059:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  13060:   free_ivector(TmodelInvind,1,NCOVMAX);
                   13061:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  13062:   
                   13063:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   13064:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  13065:   fflush(fichtm);
                   13066:   fflush(ficgp);
                   13067:   
1.227     brouard  13068:   
1.126     brouard  13069:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  13070:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   13071:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  13072:   }else{
                   13073:     printf("End of Imach\n");
                   13074:     fprintf(ficlog,"End of Imach\n");
                   13075:   }
                   13076:   printf("See log file on %s\n",filelog);
                   13077:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  13078:   /*(void) gettimeofday(&end_time,&tzp);*/
                   13079:   rend_time = time(NULL);  
                   13080:   end_time = *localtime(&rend_time);
                   13081:   /* tml = *localtime(&end_time.tm_sec); */
                   13082:   strcpy(strtend,asctime(&end_time));
1.126     brouard  13083:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   13084:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  13085:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  13086:   
1.157     brouard  13087:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   13088:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   13089:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  13090:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   13091: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   13092:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13093:   fclose(fichtm);
                   13094:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13095:   fclose(fichtmcov);
                   13096:   fclose(ficgp);
                   13097:   fclose(ficlog);
                   13098:   /*------ End -----------*/
1.227     brouard  13099:   
1.281     brouard  13100: 
                   13101: /* Executes gnuplot */
1.227     brouard  13102:   
                   13103:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  13104: #ifdef WIN32
1.227     brouard  13105:   if (_chdir(pathcd) != 0)
                   13106:     printf("Can't move to directory %s!\n",path);
                   13107:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  13108: #else
1.227     brouard  13109:     if(chdir(pathcd) != 0)
                   13110:       printf("Can't move to directory %s!\n", path);
                   13111:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  13112: #endif 
1.126     brouard  13113:     printf("Current directory %s!\n",pathcd);
                   13114:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   13115:   sprintf(plotcmd,"gnuplot");
1.157     brouard  13116: #ifdef _WIN32
1.126     brouard  13117:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   13118: #endif
                   13119:   if(!stat(plotcmd,&info)){
1.158     brouard  13120:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13121:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  13122:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  13123:     }else
                   13124:       strcpy(pplotcmd,plotcmd);
1.157     brouard  13125: #ifdef __unix
1.126     brouard  13126:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   13127:     if(!stat(plotcmd,&info)){
1.158     brouard  13128:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13129:     }else
                   13130:       strcpy(pplotcmd,plotcmd);
                   13131: #endif
                   13132:   }else
                   13133:     strcpy(pplotcmd,plotcmd);
                   13134:   
                   13135:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  13136:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.292     brouard  13137:   strcpy(pplotcmd,plotcmd);
1.227     brouard  13138:   
1.126     brouard  13139:   if((outcmd=system(plotcmd)) != 0){
1.292     brouard  13140:     printf("Error in gnuplot, command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  13141:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  13142:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.292     brouard  13143:     if((outcmd=system(plotcmd)) != 0){
1.153     brouard  13144:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.292     brouard  13145:       strcpy(plotcmd,pplotcmd);
                   13146:     }
1.126     brouard  13147:   }
1.158     brouard  13148:   printf(" Successful, please wait...");
1.126     brouard  13149:   while (z[0] != 'q') {
                   13150:     /* chdir(path); */
1.154     brouard  13151:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  13152:     scanf("%s",z);
                   13153: /*     if (z[0] == 'c') system("./imach"); */
                   13154:     if (z[0] == 'e') {
1.158     brouard  13155: #ifdef __APPLE__
1.152     brouard  13156:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  13157: #elif __linux
                   13158:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  13159: #else
1.152     brouard  13160:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  13161: #endif
                   13162:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   13163:       system(pplotcmd);
1.126     brouard  13164:     }
                   13165:     else if (z[0] == 'g') system(plotcmd);
                   13166:     else if (z[0] == 'q') exit(0);
                   13167:   }
1.227     brouard  13168: end:
1.126     brouard  13169:   while (z[0] != 'q') {
1.195     brouard  13170:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  13171:     scanf("%s",z);
                   13172:   }
1.283     brouard  13173:   printf("End\n");
1.282     brouard  13174:   exit(0);
1.126     brouard  13175: }

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