Annotation of imach/src/imach.c, revision 1.319

1.319   ! brouard     1: /* $Id: imach.c,v 1.318 2022/05/24 08:10:59 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.319   ! brouard     4:   Revision 1.318  2022/05/24 08:10:59  brouard
        !             5:   * imach.c (Module): Some attempts to find a bug of wrong estimates
        !             6:   of confidencce intervals with product in the equation modelC
        !             7: 
1.318     brouard     8:   Revision 1.317  2022/05/15 15:06:23  brouard
                      9:   * imach.c (Module):  Some minor improvements
                     10: 
1.317     brouard    11:   Revision 1.316  2022/05/11 15:11:31  brouard
                     12:   Summary: r27
                     13: 
1.316     brouard    14:   Revision 1.315  2022/05/11 15:06:32  brouard
                     15:   *** empty log message ***
                     16: 
1.315     brouard    17:   Revision 1.314  2022/04/13 17:43:09  brouard
                     18:   * imach.c (Module): Adding link to text data files
                     19: 
1.314     brouard    20:   Revision 1.313  2022/04/11 15:57:42  brouard
                     21:   * imach.c (Module): Error in rewriting the 'r' file with yearsfproj or yearsbproj fixed
                     22: 
1.313     brouard    23:   Revision 1.312  2022/04/05 21:24:39  brouard
                     24:   *** empty log message ***
                     25: 
1.312     brouard    26:   Revision 1.311  2022/04/05 21:03:51  brouard
                     27:   Summary: Fixed quantitative covariates
                     28: 
                     29:          Fixed covariates (dummy or quantitative)
                     30:        with missing values have never been allowed but are ERRORS and
                     31:        program quits. Standard deviations of fixed covariates were
                     32:        wrongly computed. Mean and standard deviations of time varying
                     33:        covariates are still not computed.
                     34: 
1.311     brouard    35:   Revision 1.310  2022/03/17 08:45:53  brouard
                     36:   Summary: 99r25
                     37: 
                     38:   Improving detection of errors: result lines should be compatible with
                     39:   the model.
                     40: 
1.310     brouard    41:   Revision 1.309  2021/05/20 12:39:14  brouard
                     42:   Summary: Version 0.99r24
                     43: 
1.309     brouard    44:   Revision 1.308  2021/03/31 13:11:57  brouard
                     45:   Summary: Version 0.99r23
                     46: 
                     47: 
                     48:   * imach.c (Module): Still bugs in the result loop. Thank to Holly Benett
                     49: 
1.308     brouard    50:   Revision 1.307  2021/03/08 18:11:32  brouard
                     51:   Summary: 0.99r22 fixed bug on result:
                     52: 
1.307     brouard    53:   Revision 1.306  2021/02/20 15:44:02  brouard
                     54:   Summary: Version 0.99r21
                     55: 
                     56:   * imach.c (Module): Fix bug on quitting after result lines!
                     57:   (Module): Version 0.99r21
                     58: 
1.306     brouard    59:   Revision 1.305  2021/02/20 15:28:30  brouard
                     60:   * imach.c (Module): Fix bug on quitting after result lines!
                     61: 
1.305     brouard    62:   Revision 1.304  2021/02/12 11:34:20  brouard
                     63:   * imach.c (Module): The use of a Windows BOM (huge) file is now an error
                     64: 
1.304     brouard    65:   Revision 1.303  2021/02/11 19:50:15  brouard
                     66:   *  (Module): imach.c Someone entered 'results:' instead of 'result:'. Now it is an error which is printed.
                     67: 
1.303     brouard    68:   Revision 1.302  2020/02/22 21:00:05  brouard
                     69:   *  (Module): imach.c Update mle=-3 (for computing Life expectancy
                     70:   and life table from the data without any state)
                     71: 
1.302     brouard    72:   Revision 1.301  2019/06/04 13:51:20  brouard
                     73:   Summary: Error in 'r'parameter file backcast yearsbproj instead of yearsfproj
                     74: 
1.301     brouard    75:   Revision 1.300  2019/05/22 19:09:45  brouard
                     76:   Summary: version 0.99r19 of May 2019
                     77: 
1.300     brouard    78:   Revision 1.299  2019/05/22 18:37:08  brouard
                     79:   Summary: Cleaned 0.99r19
                     80: 
1.299     brouard    81:   Revision 1.298  2019/05/22 18:19:56  brouard
                     82:   *** empty log message ***
                     83: 
1.298     brouard    84:   Revision 1.297  2019/05/22 17:56:10  brouard
                     85:   Summary: Fix bug by moving date2dmy and nhstepm which gaefin=-1
                     86: 
1.297     brouard    87:   Revision 1.296  2019/05/20 13:03:18  brouard
                     88:   Summary: Projection syntax simplified
                     89: 
                     90: 
                     91:   We can now start projections, forward or backward, from the mean date
                     92:   of inteviews up to or down to a number of years of projection:
                     93:   prevforecast=1 yearsfproj=15.3 mobil_average=0
                     94:   or
                     95:   prevforecast=1 starting-proj-date=1/1/2007 final-proj-date=12/31/2017 mobil_average=0
                     96:   or
                     97:   prevbackcast=1 yearsbproj=12.3 mobil_average=1
                     98:   or
                     99:   prevbackcast=1 starting-back-date=1/10/1999 final-back-date=1/1/1985 mobil_average=1
                    100: 
1.296     brouard   101:   Revision 1.295  2019/05/18 09:52:50  brouard
                    102:   Summary: doxygen tex bug
                    103: 
1.295     brouard   104:   Revision 1.294  2019/05/16 14:54:33  brouard
                    105:   Summary: There was some wrong lines added
                    106: 
1.294     brouard   107:   Revision 1.293  2019/05/09 15:17:34  brouard
                    108:   *** empty log message ***
                    109: 
1.293     brouard   110:   Revision 1.292  2019/05/09 14:17:20  brouard
                    111:   Summary: Some updates
                    112: 
1.292     brouard   113:   Revision 1.291  2019/05/09 13:44:18  brouard
                    114:   Summary: Before ncovmax
                    115: 
1.291     brouard   116:   Revision 1.290  2019/05/09 13:39:37  brouard
                    117:   Summary: 0.99r18 unlimited number of individuals
                    118: 
                    119:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
                    120: 
1.290     brouard   121:   Revision 1.289  2018/12/13 09:16:26  brouard
                    122:   Summary: Bug for young ages (<-30) will be in r17
                    123: 
1.289     brouard   124:   Revision 1.288  2018/05/02 20:58:27  brouard
                    125:   Summary: Some bugs fixed
                    126: 
1.288     brouard   127:   Revision 1.287  2018/05/01 17:57:25  brouard
                    128:   Summary: Bug fixed by providing frequencies only for non missing covariates
                    129: 
1.287     brouard   130:   Revision 1.286  2018/04/27 14:27:04  brouard
                    131:   Summary: some minor bugs
                    132: 
1.286     brouard   133:   Revision 1.285  2018/04/21 21:02:16  brouard
                    134:   Summary: Some bugs fixed, valgrind tested
                    135: 
1.285     brouard   136:   Revision 1.284  2018/04/20 05:22:13  brouard
                    137:   Summary: Computing mean and stdeviation of fixed quantitative variables
                    138: 
1.284     brouard   139:   Revision 1.283  2018/04/19 14:49:16  brouard
                    140:   Summary: Some minor bugs fixed
                    141: 
1.283     brouard   142:   Revision 1.282  2018/02/27 22:50:02  brouard
                    143:   *** empty log message ***
                    144: 
1.282     brouard   145:   Revision 1.281  2018/02/27 19:25:23  brouard
                    146:   Summary: Adding second argument for quitting
                    147: 
1.281     brouard   148:   Revision 1.280  2018/02/21 07:58:13  brouard
                    149:   Summary: 0.99r15
                    150: 
                    151:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                    152: 
1.280     brouard   153:   Revision 1.279  2017/07/20 13:35:01  brouard
                    154:   Summary: temporary working
                    155: 
1.279     brouard   156:   Revision 1.278  2017/07/19 14:09:02  brouard
                    157:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                    158: 
1.278     brouard   159:   Revision 1.277  2017/07/17 08:53:49  brouard
                    160:   Summary: BOM files can be read now
                    161: 
1.277     brouard   162:   Revision 1.276  2017/06/30 15:48:31  brouard
                    163:   Summary: Graphs improvements
                    164: 
1.276     brouard   165:   Revision 1.275  2017/06/30 13:39:33  brouard
                    166:   Summary: Saito's color
                    167: 
1.275     brouard   168:   Revision 1.274  2017/06/29 09:47:08  brouard
                    169:   Summary: Version 0.99r14
                    170: 
1.274     brouard   171:   Revision 1.273  2017/06/27 11:06:02  brouard
                    172:   Summary: More documentation on projections
                    173: 
1.273     brouard   174:   Revision 1.272  2017/06/27 10:22:40  brouard
                    175:   Summary: Color of backprojection changed from 6 to 5(yellow)
                    176: 
1.272     brouard   177:   Revision 1.271  2017/06/27 10:17:50  brouard
                    178:   Summary: Some bug with rint
                    179: 
1.271     brouard   180:   Revision 1.270  2017/05/24 05:45:29  brouard
                    181:   *** empty log message ***
                    182: 
1.270     brouard   183:   Revision 1.269  2017/05/23 08:39:25  brouard
                    184:   Summary: Code into subroutine, cleanings
                    185: 
1.269     brouard   186:   Revision 1.268  2017/05/18 20:09:32  brouard
                    187:   Summary: backprojection and confidence intervals of backprevalence
                    188: 
1.268     brouard   189:   Revision 1.267  2017/05/13 10:25:05  brouard
                    190:   Summary: temporary save for backprojection
                    191: 
1.267     brouard   192:   Revision 1.266  2017/05/13 07:26:12  brouard
                    193:   Summary: Version 0.99r13 (improvements and bugs fixed)
                    194: 
1.266     brouard   195:   Revision 1.265  2017/04/26 16:22:11  brouard
                    196:   Summary: imach 0.99r13 Some bugs fixed
                    197: 
1.265     brouard   198:   Revision 1.264  2017/04/26 06:01:29  brouard
                    199:   Summary: Labels in graphs
                    200: 
1.264     brouard   201:   Revision 1.263  2017/04/24 15:23:15  brouard
                    202:   Summary: to save
                    203: 
1.263     brouard   204:   Revision 1.262  2017/04/18 16:48:12  brouard
                    205:   *** empty log message ***
                    206: 
1.262     brouard   207:   Revision 1.261  2017/04/05 10:14:09  brouard
                    208:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                    209: 
1.261     brouard   210:   Revision 1.260  2017/04/04 17:46:59  brouard
                    211:   Summary: Gnuplot indexations fixed (humm)
                    212: 
1.260     brouard   213:   Revision 1.259  2017/04/04 13:01:16  brouard
                    214:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    215: 
1.259     brouard   216:   Revision 1.258  2017/04/03 10:17:47  brouard
                    217:   Summary: Version 0.99r12
                    218: 
                    219:   Some cleanings, conformed with updated documentation.
                    220: 
1.258     brouard   221:   Revision 1.257  2017/03/29 16:53:30  brouard
                    222:   Summary: Temp
                    223: 
1.257     brouard   224:   Revision 1.256  2017/03/27 05:50:23  brouard
                    225:   Summary: Temporary
                    226: 
1.256     brouard   227:   Revision 1.255  2017/03/08 16:02:28  brouard
                    228:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    229: 
1.255     brouard   230:   Revision 1.254  2017/03/08 07:13:00  brouard
                    231:   Summary: Fixing data parameter line
                    232: 
1.254     brouard   233:   Revision 1.253  2016/12/15 11:59:41  brouard
                    234:   Summary: 0.99 in progress
                    235: 
1.253     brouard   236:   Revision 1.252  2016/09/15 21:15:37  brouard
                    237:   *** empty log message ***
                    238: 
1.252     brouard   239:   Revision 1.251  2016/09/15 15:01:13  brouard
                    240:   Summary: not working
                    241: 
1.251     brouard   242:   Revision 1.250  2016/09/08 16:07:27  brouard
                    243:   Summary: continue
                    244: 
1.250     brouard   245:   Revision 1.249  2016/09/07 17:14:18  brouard
                    246:   Summary: Starting values from frequencies
                    247: 
1.249     brouard   248:   Revision 1.248  2016/09/07 14:10:18  brouard
                    249:   *** empty log message ***
                    250: 
1.248     brouard   251:   Revision 1.247  2016/09/02 11:11:21  brouard
                    252:   *** empty log message ***
                    253: 
1.247     brouard   254:   Revision 1.246  2016/09/02 08:49:22  brouard
                    255:   *** empty log message ***
                    256: 
1.246     brouard   257:   Revision 1.245  2016/09/02 07:25:01  brouard
                    258:   *** empty log message ***
                    259: 
1.245     brouard   260:   Revision 1.244  2016/09/02 07:17:34  brouard
                    261:   *** empty log message ***
                    262: 
1.244     brouard   263:   Revision 1.243  2016/09/02 06:45:35  brouard
                    264:   *** empty log message ***
                    265: 
1.243     brouard   266:   Revision 1.242  2016/08/30 15:01:20  brouard
                    267:   Summary: Fixing a lots
                    268: 
1.242     brouard   269:   Revision 1.241  2016/08/29 17:17:25  brouard
                    270:   Summary: gnuplot problem in Back projection to fix
                    271: 
1.241     brouard   272:   Revision 1.240  2016/08/29 07:53:18  brouard
                    273:   Summary: Better
                    274: 
1.240     brouard   275:   Revision 1.239  2016/08/26 15:51:03  brouard
                    276:   Summary: Improvement in Powell output in order to copy and paste
                    277: 
                    278:   Author:
                    279: 
1.239     brouard   280:   Revision 1.238  2016/08/26 14:23:35  brouard
                    281:   Summary: Starting tests of 0.99
                    282: 
1.238     brouard   283:   Revision 1.237  2016/08/26 09:20:19  brouard
                    284:   Summary: to valgrind
                    285: 
1.237     brouard   286:   Revision 1.236  2016/08/25 10:50:18  brouard
                    287:   *** empty log message ***
                    288: 
1.236     brouard   289:   Revision 1.235  2016/08/25 06:59:23  brouard
                    290:   *** empty log message ***
                    291: 
1.235     brouard   292:   Revision 1.234  2016/08/23 16:51:20  brouard
                    293:   *** empty log message ***
                    294: 
1.234     brouard   295:   Revision 1.233  2016/08/23 07:40:50  brouard
                    296:   Summary: not working
                    297: 
1.233     brouard   298:   Revision 1.232  2016/08/22 14:20:21  brouard
                    299:   Summary: not working
                    300: 
1.232     brouard   301:   Revision 1.231  2016/08/22 07:17:15  brouard
                    302:   Summary: not working
                    303: 
1.231     brouard   304:   Revision 1.230  2016/08/22 06:55:53  brouard
                    305:   Summary: Not working
                    306: 
1.230     brouard   307:   Revision 1.229  2016/07/23 09:45:53  brouard
                    308:   Summary: Completing for func too
                    309: 
1.229     brouard   310:   Revision 1.228  2016/07/22 17:45:30  brouard
                    311:   Summary: Fixing some arrays, still debugging
                    312: 
1.227     brouard   313:   Revision 1.226  2016/07/12 18:42:34  brouard
                    314:   Summary: temp
                    315: 
1.226     brouard   316:   Revision 1.225  2016/07/12 08:40:03  brouard
                    317:   Summary: saving but not running
                    318: 
1.225     brouard   319:   Revision 1.224  2016/07/01 13:16:01  brouard
                    320:   Summary: Fixes
                    321: 
1.224     brouard   322:   Revision 1.223  2016/02/19 09:23:35  brouard
                    323:   Summary: temporary
                    324: 
1.223     brouard   325:   Revision 1.222  2016/02/17 08:14:50  brouard
                    326:   Summary: Probably last 0.98 stable version 0.98r6
                    327: 
1.222     brouard   328:   Revision 1.221  2016/02/15 23:35:36  brouard
                    329:   Summary: minor bug
                    330: 
1.220     brouard   331:   Revision 1.219  2016/02/15 00:48:12  brouard
                    332:   *** empty log message ***
                    333: 
1.219     brouard   334:   Revision 1.218  2016/02/12 11:29:23  brouard
                    335:   Summary: 0.99 Back projections
                    336: 
1.218     brouard   337:   Revision 1.217  2015/12/23 17:18:31  brouard
                    338:   Summary: Experimental backcast
                    339: 
1.217     brouard   340:   Revision 1.216  2015/12/18 17:32:11  brouard
                    341:   Summary: 0.98r4 Warning and status=-2
                    342: 
                    343:   Version 0.98r4 is now:
                    344:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    345:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    346:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    347: 
1.216     brouard   348:   Revision 1.215  2015/12/16 08:52:24  brouard
                    349:   Summary: 0.98r4 working
                    350: 
1.215     brouard   351:   Revision 1.214  2015/12/16 06:57:54  brouard
                    352:   Summary: temporary not working
                    353: 
1.214     brouard   354:   Revision 1.213  2015/12/11 18:22:17  brouard
                    355:   Summary: 0.98r4
                    356: 
1.213     brouard   357:   Revision 1.212  2015/11/21 12:47:24  brouard
                    358:   Summary: minor typo
                    359: 
1.212     brouard   360:   Revision 1.211  2015/11/21 12:41:11  brouard
                    361:   Summary: 0.98r3 with some graph of projected cross-sectional
                    362: 
                    363:   Author: Nicolas Brouard
                    364: 
1.211     brouard   365:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   366:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   367:   Summary: Adding ftolpl parameter
                    368:   Author: N Brouard
                    369: 
                    370:   We had difficulties to get smoothed confidence intervals. It was due
                    371:   to the period prevalence which wasn't computed accurately. The inner
                    372:   parameter ftolpl is now an outer parameter of the .imach parameter
                    373:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    374:   computation are long.
                    375: 
1.209     brouard   376:   Revision 1.208  2015/11/17 14:31:57  brouard
                    377:   Summary: temporary
                    378: 
1.208     brouard   379:   Revision 1.207  2015/10/27 17:36:57  brouard
                    380:   *** empty log message ***
                    381: 
1.207     brouard   382:   Revision 1.206  2015/10/24 07:14:11  brouard
                    383:   *** empty log message ***
                    384: 
1.206     brouard   385:   Revision 1.205  2015/10/23 15:50:53  brouard
                    386:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    387: 
1.205     brouard   388:   Revision 1.204  2015/10/01 16:20:26  brouard
                    389:   Summary: Some new graphs of contribution to likelihood
                    390: 
1.204     brouard   391:   Revision 1.203  2015/09/30 17:45:14  brouard
                    392:   Summary: looking at better estimation of the hessian
                    393: 
                    394:   Also a better criteria for convergence to the period prevalence And
                    395:   therefore adding the number of years needed to converge. (The
                    396:   prevalence in any alive state shold sum to one
                    397: 
1.203     brouard   398:   Revision 1.202  2015/09/22 19:45:16  brouard
                    399:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    400: 
1.202     brouard   401:   Revision 1.201  2015/09/15 17:34:58  brouard
                    402:   Summary: 0.98r0
                    403: 
                    404:   - Some new graphs like suvival functions
                    405:   - Some bugs fixed like model=1+age+V2.
                    406: 
1.201     brouard   407:   Revision 1.200  2015/09/09 16:53:55  brouard
                    408:   Summary: Big bug thanks to Flavia
                    409: 
                    410:   Even model=1+age+V2. did not work anymore
                    411: 
1.200     brouard   412:   Revision 1.199  2015/09/07 14:09:23  brouard
                    413:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    414: 
1.199     brouard   415:   Revision 1.198  2015/09/03 07:14:39  brouard
                    416:   Summary: 0.98q5 Flavia
                    417: 
1.198     brouard   418:   Revision 1.197  2015/09/01 18:24:39  brouard
                    419:   *** empty log message ***
                    420: 
1.197     brouard   421:   Revision 1.196  2015/08/18 23:17:52  brouard
                    422:   Summary: 0.98q5
                    423: 
1.196     brouard   424:   Revision 1.195  2015/08/18 16:28:39  brouard
                    425:   Summary: Adding a hack for testing purpose
                    426: 
                    427:   After reading the title, ftol and model lines, if the comment line has
                    428:   a q, starting with #q, the answer at the end of the run is quit. It
                    429:   permits to run test files in batch with ctest. The former workaround was
                    430:   $ echo q | imach foo.imach
                    431: 
1.195     brouard   432:   Revision 1.194  2015/08/18 13:32:00  brouard
                    433:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    434: 
1.194     brouard   435:   Revision 1.193  2015/08/04 07:17:42  brouard
                    436:   Summary: 0.98q4
                    437: 
1.193     brouard   438:   Revision 1.192  2015/07/16 16:49:02  brouard
                    439:   Summary: Fixing some outputs
                    440: 
1.192     brouard   441:   Revision 1.191  2015/07/14 10:00:33  brouard
                    442:   Summary: Some fixes
                    443: 
1.191     brouard   444:   Revision 1.190  2015/05/05 08:51:13  brouard
                    445:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    446: 
                    447:   Fix 1+age+.
                    448: 
1.190     brouard   449:   Revision 1.189  2015/04/30 14:45:16  brouard
                    450:   Summary: 0.98q2
                    451: 
1.189     brouard   452:   Revision 1.188  2015/04/30 08:27:53  brouard
                    453:   *** empty log message ***
                    454: 
1.188     brouard   455:   Revision 1.187  2015/04/29 09:11:15  brouard
                    456:   *** empty log message ***
                    457: 
1.187     brouard   458:   Revision 1.186  2015/04/23 12:01:52  brouard
                    459:   Summary: V1*age is working now, version 0.98q1
                    460: 
                    461:   Some codes had been disabled in order to simplify and Vn*age was
                    462:   working in the optimization phase, ie, giving correct MLE parameters,
                    463:   but, as usual, outputs were not correct and program core dumped.
                    464: 
1.186     brouard   465:   Revision 1.185  2015/03/11 13:26:42  brouard
                    466:   Summary: Inclusion of compile and links command line for Intel Compiler
                    467: 
1.185     brouard   468:   Revision 1.184  2015/03/11 11:52:39  brouard
                    469:   Summary: Back from Windows 8. Intel Compiler
                    470: 
1.184     brouard   471:   Revision 1.183  2015/03/10 20:34:32  brouard
                    472:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    473: 
                    474:   We use directest instead of original Powell test; probably no
                    475:   incidence on the results, but better justifications;
                    476:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    477:   wrong results.
                    478: 
1.183     brouard   479:   Revision 1.182  2015/02/12 08:19:57  brouard
                    480:   Summary: Trying to keep directest which seems simpler and more general
                    481:   Author: Nicolas Brouard
                    482: 
1.182     brouard   483:   Revision 1.181  2015/02/11 23:22:24  brouard
                    484:   Summary: Comments on Powell added
                    485: 
                    486:   Author:
                    487: 
1.181     brouard   488:   Revision 1.180  2015/02/11 17:33:45  brouard
                    489:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    490: 
1.180     brouard   491:   Revision 1.179  2015/01/04 09:57:06  brouard
                    492:   Summary: back to OS/X
                    493: 
1.179     brouard   494:   Revision 1.178  2015/01/04 09:35:48  brouard
                    495:   *** empty log message ***
                    496: 
1.178     brouard   497:   Revision 1.177  2015/01/03 18:40:56  brouard
                    498:   Summary: Still testing ilc32 on OSX
                    499: 
1.177     brouard   500:   Revision 1.176  2015/01/03 16:45:04  brouard
                    501:   *** empty log message ***
                    502: 
1.176     brouard   503:   Revision 1.175  2015/01/03 16:33:42  brouard
                    504:   *** empty log message ***
                    505: 
1.175     brouard   506:   Revision 1.174  2015/01/03 16:15:49  brouard
                    507:   Summary: Still in cross-compilation
                    508: 
1.174     brouard   509:   Revision 1.173  2015/01/03 12:06:26  brouard
                    510:   Summary: trying to detect cross-compilation
                    511: 
1.173     brouard   512:   Revision 1.172  2014/12/27 12:07:47  brouard
                    513:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    514: 
1.172     brouard   515:   Revision 1.171  2014/12/23 13:26:59  brouard
                    516:   Summary: Back from Visual C
                    517: 
                    518:   Still problem with utsname.h on Windows
                    519: 
1.171     brouard   520:   Revision 1.170  2014/12/23 11:17:12  brouard
                    521:   Summary: Cleaning some \%% back to %%
                    522: 
                    523:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    524: 
1.170     brouard   525:   Revision 1.169  2014/12/22 23:08:31  brouard
                    526:   Summary: 0.98p
                    527: 
                    528:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    529: 
1.169     brouard   530:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   531:   Summary: update
1.169     brouard   532: 
1.168     brouard   533:   Revision 1.167  2014/12/22 13:50:56  brouard
                    534:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    535: 
                    536:   Testing on Linux 64
                    537: 
1.167     brouard   538:   Revision 1.166  2014/12/22 11:40:47  brouard
                    539:   *** empty log message ***
                    540: 
1.166     brouard   541:   Revision 1.165  2014/12/16 11:20:36  brouard
                    542:   Summary: After compiling on Visual C
                    543: 
                    544:   * imach.c (Module): Merging 1.61 to 1.162
                    545: 
1.165     brouard   546:   Revision 1.164  2014/12/16 10:52:11  brouard
                    547:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    548: 
                    549:   * imach.c (Module): Merging 1.61 to 1.162
                    550: 
1.164     brouard   551:   Revision 1.163  2014/12/16 10:30:11  brouard
                    552:   * imach.c (Module): Merging 1.61 to 1.162
                    553: 
1.163     brouard   554:   Revision 1.162  2014/09/25 11:43:39  brouard
                    555:   Summary: temporary backup 0.99!
                    556: 
1.162     brouard   557:   Revision 1.1  2014/09/16 11:06:58  brouard
                    558:   Summary: With some code (wrong) for nlopt
                    559: 
                    560:   Author:
                    561: 
                    562:   Revision 1.161  2014/09/15 20:41:41  brouard
                    563:   Summary: Problem with macro SQR on Intel compiler
                    564: 
1.161     brouard   565:   Revision 1.160  2014/09/02 09:24:05  brouard
                    566:   *** empty log message ***
                    567: 
1.160     brouard   568:   Revision 1.159  2014/09/01 10:34:10  brouard
                    569:   Summary: WIN32
                    570:   Author: Brouard
                    571: 
1.159     brouard   572:   Revision 1.158  2014/08/27 17:11:51  brouard
                    573:   *** empty log message ***
                    574: 
1.158     brouard   575:   Revision 1.157  2014/08/27 16:26:55  brouard
                    576:   Summary: Preparing windows Visual studio version
                    577:   Author: Brouard
                    578: 
                    579:   In order to compile on Visual studio, time.h is now correct and time_t
                    580:   and tm struct should be used. difftime should be used but sometimes I
                    581:   just make the differences in raw time format (time(&now).
                    582:   Trying to suppress #ifdef LINUX
                    583:   Add xdg-open for __linux in order to open default browser.
                    584: 
1.157     brouard   585:   Revision 1.156  2014/08/25 20:10:10  brouard
                    586:   *** empty log message ***
                    587: 
1.156     brouard   588:   Revision 1.155  2014/08/25 18:32:34  brouard
                    589:   Summary: New compile, minor changes
                    590:   Author: Brouard
                    591: 
1.155     brouard   592:   Revision 1.154  2014/06/20 17:32:08  brouard
                    593:   Summary: Outputs now all graphs of convergence to period prevalence
                    594: 
1.154     brouard   595:   Revision 1.153  2014/06/20 16:45:46  brouard
                    596:   Summary: If 3 live state, convergence to period prevalence on same graph
                    597:   Author: Brouard
                    598: 
1.153     brouard   599:   Revision 1.152  2014/06/18 17:54:09  brouard
                    600:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    601: 
1.152     brouard   602:   Revision 1.151  2014/06/18 16:43:30  brouard
                    603:   *** empty log message ***
                    604: 
1.151     brouard   605:   Revision 1.150  2014/06/18 16:42:35  brouard
                    606:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    607:   Author: brouard
                    608: 
1.150     brouard   609:   Revision 1.149  2014/06/18 15:51:14  brouard
                    610:   Summary: Some fixes in parameter files errors
                    611:   Author: Nicolas Brouard
                    612: 
1.149     brouard   613:   Revision 1.148  2014/06/17 17:38:48  brouard
                    614:   Summary: Nothing new
                    615:   Author: Brouard
                    616: 
                    617:   Just a new packaging for OS/X version 0.98nS
                    618: 
1.148     brouard   619:   Revision 1.147  2014/06/16 10:33:11  brouard
                    620:   *** empty log message ***
                    621: 
1.147     brouard   622:   Revision 1.146  2014/06/16 10:20:28  brouard
                    623:   Summary: Merge
                    624:   Author: Brouard
                    625: 
                    626:   Merge, before building revised version.
                    627: 
1.146     brouard   628:   Revision 1.145  2014/06/10 21:23:15  brouard
                    629:   Summary: Debugging with valgrind
                    630:   Author: Nicolas Brouard
                    631: 
                    632:   Lot of changes in order to output the results with some covariates
                    633:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    634:   improve the code.
                    635:   No more memory valgrind error but a lot has to be done in order to
                    636:   continue the work of splitting the code into subroutines.
                    637:   Also, decodemodel has been improved. Tricode is still not
                    638:   optimal. nbcode should be improved. Documentation has been added in
                    639:   the source code.
                    640: 
1.144     brouard   641:   Revision 1.143  2014/01/26 09:45:38  brouard
                    642:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    643: 
                    644:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    645:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    646: 
1.143     brouard   647:   Revision 1.142  2014/01/26 03:57:36  brouard
                    648:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    649: 
                    650:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    651: 
1.142     brouard   652:   Revision 1.141  2014/01/26 02:42:01  brouard
                    653:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    654: 
1.141     brouard   655:   Revision 1.140  2011/09/02 10:37:54  brouard
                    656:   Summary: times.h is ok with mingw32 now.
                    657: 
1.140     brouard   658:   Revision 1.139  2010/06/14 07:50:17  brouard
                    659:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    660:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    661: 
1.139     brouard   662:   Revision 1.138  2010/04/30 18:19:40  brouard
                    663:   *** empty log message ***
                    664: 
1.138     brouard   665:   Revision 1.137  2010/04/29 18:11:38  brouard
                    666:   (Module): Checking covariates for more complex models
                    667:   than V1+V2. A lot of change to be done. Unstable.
                    668: 
1.137     brouard   669:   Revision 1.136  2010/04/26 20:30:53  brouard
                    670:   (Module): merging some libgsl code. Fixing computation
                    671:   of likelione (using inter/intrapolation if mle = 0) in order to
                    672:   get same likelihood as if mle=1.
                    673:   Some cleaning of code and comments added.
                    674: 
1.136     brouard   675:   Revision 1.135  2009/10/29 15:33:14  brouard
                    676:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    677: 
1.135     brouard   678:   Revision 1.134  2009/10/29 13:18:53  brouard
                    679:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    680: 
1.134     brouard   681:   Revision 1.133  2009/07/06 10:21:25  brouard
                    682:   just nforces
                    683: 
1.133     brouard   684:   Revision 1.132  2009/07/06 08:22:05  brouard
                    685:   Many tings
                    686: 
1.132     brouard   687:   Revision 1.131  2009/06/20 16:22:47  brouard
                    688:   Some dimensions resccaled
                    689: 
1.131     brouard   690:   Revision 1.130  2009/05/26 06:44:34  brouard
                    691:   (Module): Max Covariate is now set to 20 instead of 8. A
                    692:   lot of cleaning with variables initialized to 0. Trying to make
                    693:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    694: 
1.130     brouard   695:   Revision 1.129  2007/08/31 13:49:27  lievre
                    696:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    697: 
1.129     lievre    698:   Revision 1.128  2006/06/30 13:02:05  brouard
                    699:   (Module): Clarifications on computing e.j
                    700: 
1.128     brouard   701:   Revision 1.127  2006/04/28 18:11:50  brouard
                    702:   (Module): Yes the sum of survivors was wrong since
                    703:   imach-114 because nhstepm was no more computed in the age
                    704:   loop. Now we define nhstepma in the age loop.
                    705:   (Module): In order to speed up (in case of numerous covariates) we
                    706:   compute health expectancies (without variances) in a first step
                    707:   and then all the health expectancies with variances or standard
                    708:   deviation (needs data from the Hessian matrices) which slows the
                    709:   computation.
                    710:   In the future we should be able to stop the program is only health
                    711:   expectancies and graph are needed without standard deviations.
                    712: 
1.127     brouard   713:   Revision 1.126  2006/04/28 17:23:28  brouard
                    714:   (Module): Yes the sum of survivors was wrong since
                    715:   imach-114 because nhstepm was no more computed in the age
                    716:   loop. Now we define nhstepma in the age loop.
                    717:   Version 0.98h
                    718: 
1.126     brouard   719:   Revision 1.125  2006/04/04 15:20:31  lievre
                    720:   Errors in calculation of health expectancies. Age was not initialized.
                    721:   Forecasting file added.
                    722: 
                    723:   Revision 1.124  2006/03/22 17:13:53  lievre
                    724:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    725:   The log-likelihood is printed in the log file
                    726: 
                    727:   Revision 1.123  2006/03/20 10:52:43  brouard
                    728:   * imach.c (Module): <title> changed, corresponds to .htm file
                    729:   name. <head> headers where missing.
                    730: 
                    731:   * imach.c (Module): Weights can have a decimal point as for
                    732:   English (a comma might work with a correct LC_NUMERIC environment,
                    733:   otherwise the weight is truncated).
                    734:   Modification of warning when the covariates values are not 0 or
                    735:   1.
                    736:   Version 0.98g
                    737: 
                    738:   Revision 1.122  2006/03/20 09:45:41  brouard
                    739:   (Module): Weights can have a decimal point as for
                    740:   English (a comma might work with a correct LC_NUMERIC environment,
                    741:   otherwise the weight is truncated).
                    742:   Modification of warning when the covariates values are not 0 or
                    743:   1.
                    744:   Version 0.98g
                    745: 
                    746:   Revision 1.121  2006/03/16 17:45:01  lievre
                    747:   * imach.c (Module): Comments concerning covariates added
                    748: 
                    749:   * imach.c (Module): refinements in the computation of lli if
                    750:   status=-2 in order to have more reliable computation if stepm is
                    751:   not 1 month. Version 0.98f
                    752: 
                    753:   Revision 1.120  2006/03/16 15:10:38  lievre
                    754:   (Module): refinements in the computation of lli if
                    755:   status=-2 in order to have more reliable computation if stepm is
                    756:   not 1 month. Version 0.98f
                    757: 
                    758:   Revision 1.119  2006/03/15 17:42:26  brouard
                    759:   (Module): Bug if status = -2, the loglikelihood was
                    760:   computed as likelihood omitting the logarithm. Version O.98e
                    761: 
                    762:   Revision 1.118  2006/03/14 18:20:07  brouard
                    763:   (Module): varevsij Comments added explaining the second
                    764:   table of variances if popbased=1 .
                    765:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    766:   (Module): Function pstamp added
                    767:   (Module): Version 0.98d
                    768: 
                    769:   Revision 1.117  2006/03/14 17:16:22  brouard
                    770:   (Module): varevsij Comments added explaining the second
                    771:   table of variances if popbased=1 .
                    772:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    773:   (Module): Function pstamp added
                    774:   (Module): Version 0.98d
                    775: 
                    776:   Revision 1.116  2006/03/06 10:29:27  brouard
                    777:   (Module): Variance-covariance wrong links and
                    778:   varian-covariance of ej. is needed (Saito).
                    779: 
                    780:   Revision 1.115  2006/02/27 12:17:45  brouard
                    781:   (Module): One freematrix added in mlikeli! 0.98c
                    782: 
                    783:   Revision 1.114  2006/02/26 12:57:58  brouard
                    784:   (Module): Some improvements in processing parameter
                    785:   filename with strsep.
                    786: 
                    787:   Revision 1.113  2006/02/24 14:20:24  brouard
                    788:   (Module): Memory leaks checks with valgrind and:
                    789:   datafile was not closed, some imatrix were not freed and on matrix
                    790:   allocation too.
                    791: 
                    792:   Revision 1.112  2006/01/30 09:55:26  brouard
                    793:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    794: 
                    795:   Revision 1.111  2006/01/25 20:38:18  brouard
                    796:   (Module): Lots of cleaning and bugs added (Gompertz)
                    797:   (Module): Comments can be added in data file. Missing date values
                    798:   can be a simple dot '.'.
                    799: 
                    800:   Revision 1.110  2006/01/25 00:51:50  brouard
                    801:   (Module): Lots of cleaning and bugs added (Gompertz)
                    802: 
                    803:   Revision 1.109  2006/01/24 19:37:15  brouard
                    804:   (Module): Comments (lines starting with a #) are allowed in data.
                    805: 
                    806:   Revision 1.108  2006/01/19 18:05:42  lievre
                    807:   Gnuplot problem appeared...
                    808:   To be fixed
                    809: 
                    810:   Revision 1.107  2006/01/19 16:20:37  brouard
                    811:   Test existence of gnuplot in imach path
                    812: 
                    813:   Revision 1.106  2006/01/19 13:24:36  brouard
                    814:   Some cleaning and links added in html output
                    815: 
                    816:   Revision 1.105  2006/01/05 20:23:19  lievre
                    817:   *** empty log message ***
                    818: 
                    819:   Revision 1.104  2005/09/30 16:11:43  lievre
                    820:   (Module): sump fixed, loop imx fixed, and simplifications.
                    821:   (Module): If the status is missing at the last wave but we know
                    822:   that the person is alive, then we can code his/her status as -2
                    823:   (instead of missing=-1 in earlier versions) and his/her
                    824:   contributions to the likelihood is 1 - Prob of dying from last
                    825:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    826:   the healthy state at last known wave). Version is 0.98
                    827: 
                    828:   Revision 1.103  2005/09/30 15:54:49  lievre
                    829:   (Module): sump fixed, loop imx fixed, and simplifications.
                    830: 
                    831:   Revision 1.102  2004/09/15 17:31:30  brouard
                    832:   Add the possibility to read data file including tab characters.
                    833: 
                    834:   Revision 1.101  2004/09/15 10:38:38  brouard
                    835:   Fix on curr_time
                    836: 
                    837:   Revision 1.100  2004/07/12 18:29:06  brouard
                    838:   Add version for Mac OS X. Just define UNIX in Makefile
                    839: 
                    840:   Revision 1.99  2004/06/05 08:57:40  brouard
                    841:   *** empty log message ***
                    842: 
                    843:   Revision 1.98  2004/05/16 15:05:56  brouard
                    844:   New version 0.97 . First attempt to estimate force of mortality
                    845:   directly from the data i.e. without the need of knowing the health
                    846:   state at each age, but using a Gompertz model: log u =a + b*age .
                    847:   This is the basic analysis of mortality and should be done before any
                    848:   other analysis, in order to test if the mortality estimated from the
                    849:   cross-longitudinal survey is different from the mortality estimated
                    850:   from other sources like vital statistic data.
                    851: 
                    852:   The same imach parameter file can be used but the option for mle should be -3.
                    853: 
1.133     brouard   854:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   855:   former routines in order to include the new code within the former code.
                    856: 
                    857:   The output is very simple: only an estimate of the intercept and of
                    858:   the slope with 95% confident intervals.
                    859: 
                    860:   Current limitations:
                    861:   A) Even if you enter covariates, i.e. with the
                    862:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    863:   B) There is no computation of Life Expectancy nor Life Table.
                    864: 
                    865:   Revision 1.97  2004/02/20 13:25:42  lievre
                    866:   Version 0.96d. Population forecasting command line is (temporarily)
                    867:   suppressed.
                    868: 
                    869:   Revision 1.96  2003/07/15 15:38:55  brouard
                    870:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    871:   rewritten within the same printf. Workaround: many printfs.
                    872: 
                    873:   Revision 1.95  2003/07/08 07:54:34  brouard
                    874:   * imach.c (Repository):
                    875:   (Repository): Using imachwizard code to output a more meaningful covariance
                    876:   matrix (cov(a12,c31) instead of numbers.
                    877: 
                    878:   Revision 1.94  2003/06/27 13:00:02  brouard
                    879:   Just cleaning
                    880: 
                    881:   Revision 1.93  2003/06/25 16:33:55  brouard
                    882:   (Module): On windows (cygwin) function asctime_r doesn't
                    883:   exist so I changed back to asctime which exists.
                    884:   (Module): Version 0.96b
                    885: 
                    886:   Revision 1.92  2003/06/25 16:30:45  brouard
                    887:   (Module): On windows (cygwin) function asctime_r doesn't
                    888:   exist so I changed back to asctime which exists.
                    889: 
                    890:   Revision 1.91  2003/06/25 15:30:29  brouard
                    891:   * imach.c (Repository): Duplicated warning errors corrected.
                    892:   (Repository): Elapsed time after each iteration is now output. It
                    893:   helps to forecast when convergence will be reached. Elapsed time
                    894:   is stamped in powell.  We created a new html file for the graphs
                    895:   concerning matrix of covariance. It has extension -cov.htm.
                    896: 
                    897:   Revision 1.90  2003/06/24 12:34:15  brouard
                    898:   (Module): Some bugs corrected for windows. Also, when
                    899:   mle=-1 a template is output in file "or"mypar.txt with the design
                    900:   of the covariance matrix to be input.
                    901: 
                    902:   Revision 1.89  2003/06/24 12:30:52  brouard
                    903:   (Module): Some bugs corrected for windows. Also, when
                    904:   mle=-1 a template is output in file "or"mypar.txt with the design
                    905:   of the covariance matrix to be input.
                    906: 
                    907:   Revision 1.88  2003/06/23 17:54:56  brouard
                    908:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    909: 
                    910:   Revision 1.87  2003/06/18 12:26:01  brouard
                    911:   Version 0.96
                    912: 
                    913:   Revision 1.86  2003/06/17 20:04:08  brouard
                    914:   (Module): Change position of html and gnuplot routines and added
                    915:   routine fileappend.
                    916: 
                    917:   Revision 1.85  2003/06/17 13:12:43  brouard
                    918:   * imach.c (Repository): Check when date of death was earlier that
                    919:   current date of interview. It may happen when the death was just
                    920:   prior to the death. In this case, dh was negative and likelihood
                    921:   was wrong (infinity). We still send an "Error" but patch by
                    922:   assuming that the date of death was just one stepm after the
                    923:   interview.
                    924:   (Repository): Because some people have very long ID (first column)
                    925:   we changed int to long in num[] and we added a new lvector for
                    926:   memory allocation. But we also truncated to 8 characters (left
                    927:   truncation)
                    928:   (Repository): No more line truncation errors.
                    929: 
                    930:   Revision 1.84  2003/06/13 21:44:43  brouard
                    931:   * imach.c (Repository): Replace "freqsummary" at a correct
                    932:   place. It differs from routine "prevalence" which may be called
                    933:   many times. Probs is memory consuming and must be used with
                    934:   parcimony.
                    935:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    936: 
                    937:   Revision 1.83  2003/06/10 13:39:11  lievre
                    938:   *** empty log message ***
                    939: 
                    940:   Revision 1.82  2003/06/05 15:57:20  brouard
                    941:   Add log in  imach.c and  fullversion number is now printed.
                    942: 
                    943: */
                    944: /*
                    945:    Interpolated Markov Chain
                    946: 
                    947:   Short summary of the programme:
                    948:   
1.227     brouard   949:   This program computes Healthy Life Expectancies or State-specific
                    950:   (if states aren't health statuses) Expectancies from
                    951:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    952: 
                    953:   -1- a first survey ("cross") where individuals from different ages
                    954:   are interviewed on their health status or degree of disability (in
                    955:   the case of a health survey which is our main interest)
                    956: 
                    957:   -2- at least a second wave of interviews ("longitudinal") which
                    958:   measure each change (if any) in individual health status.  Health
                    959:   expectancies are computed from the time spent in each health state
                    960:   according to a model. More health states you consider, more time is
                    961:   necessary to reach the Maximum Likelihood of the parameters involved
                    962:   in the model.  The simplest model is the multinomial logistic model
                    963:   where pij is the probability to be observed in state j at the second
                    964:   wave conditional to be observed in state i at the first
                    965:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    966:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    967:   have a more complex model than "constant and age", you should modify
                    968:   the program where the markup *Covariates have to be included here
                    969:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   970:   convergence.
                    971: 
                    972:   The advantage of this computer programme, compared to a simple
                    973:   multinomial logistic model, is clear when the delay between waves is not
                    974:   identical for each individual. Also, if a individual missed an
                    975:   intermediate interview, the information is lost, but taken into
                    976:   account using an interpolation or extrapolation.  
                    977: 
                    978:   hPijx is the probability to be observed in state i at age x+h
                    979:   conditional to the observed state i at age x. The delay 'h' can be
                    980:   split into an exact number (nh*stepm) of unobserved intermediate
                    981:   states. This elementary transition (by month, quarter,
                    982:   semester or year) is modelled as a multinomial logistic.  The hPx
                    983:   matrix is simply the matrix product of nh*stepm elementary matrices
                    984:   and the contribution of each individual to the likelihood is simply
                    985:   hPijx.
                    986: 
                    987:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   988:   of the life expectancies. It also computes the period (stable) prevalence.
                    989: 
                    990: Back prevalence and projections:
1.227     brouard   991: 
                    992:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    993:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    994:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    995:    mobilavproj)
                    996: 
                    997:     Computes the back prevalence limit for any combination of
                    998:     covariate values k at any age between ageminpar and agemaxpar and
                    999:     returns it in **bprlim. In the loops,
                   1000: 
                   1001:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                   1002:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                   1003: 
                   1004:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard  1005:    Computes for any combination of covariates k and any age between bage and fage 
                   1006:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   1007:                        oldm=oldms;savm=savms;
1.227     brouard  1008: 
1.267     brouard  1009:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard  1010:      Computes the transition matrix starting at age 'age' over
                   1011:      'nhstepm*hstepm*stepm' months (i.e. until
                   1012:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard  1013:      nhstepm*hstepm matrices. 
                   1014: 
                   1015:      Returns p3mat[i][j][h] after calling
                   1016:      p3mat[i][j][h]=matprod2(newm,
                   1017:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                   1018:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                   1019:      oldm);
1.226     brouard  1020: 
                   1021: Important routines
                   1022: 
                   1023: - func (or funcone), computes logit (pij) distinguishing
                   1024:   o fixed variables (single or product dummies or quantitative);
                   1025:   o varying variables by:
                   1026:    (1) wave (single, product dummies, quantitative), 
                   1027:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                   1028:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                   1029:        % varying dummy (not done) or quantitative (not done);
                   1030: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                   1031:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                   1032: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                   1033:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                   1034:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard  1035: 
1.226     brouard  1036: 
                   1037:   
1.133     brouard  1038:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                   1039:            Institut national d'études démographiques, Paris.
1.126     brouard  1040:   This software have been partly granted by Euro-REVES, a concerted action
                   1041:   from the European Union.
                   1042:   It is copyrighted identically to a GNU software product, ie programme and
                   1043:   software can be distributed freely for non commercial use. Latest version
                   1044:   can be accessed at http://euroreves.ined.fr/imach .
                   1045: 
                   1046:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                   1047:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                   1048:   
                   1049:   **********************************************************************/
                   1050: /*
                   1051:   main
                   1052:   read parameterfile
                   1053:   read datafile
                   1054:   concatwav
                   1055:   freqsummary
                   1056:   if (mle >= 1)
                   1057:     mlikeli
                   1058:   print results files
                   1059:   if mle==1 
                   1060:      computes hessian
                   1061:   read end of parameter file: agemin, agemax, bage, fage, estepm
                   1062:       begin-prev-date,...
                   1063:   open gnuplot file
                   1064:   open html file
1.145     brouard  1065:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                   1066:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                   1067:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                   1068:     freexexit2 possible for memory heap.
                   1069: 
                   1070:   h Pij x                         | pij_nom  ficrestpij
                   1071:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                   1072:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                   1073:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                   1074: 
                   1075:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                   1076:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                   1077:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                   1078:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                   1079:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                   1080: 
1.126     brouard  1081:   forecasting if prevfcast==1 prevforecast call prevalence()
                   1082:   health expectancies
                   1083:   Variance-covariance of DFLE
                   1084:   prevalence()
                   1085:    movingaverage()
                   1086:   varevsij() 
                   1087:   if popbased==1 varevsij(,popbased)
                   1088:   total life expectancies
                   1089:   Variance of period (stable) prevalence
                   1090:  end
                   1091: */
                   1092: 
1.187     brouard  1093: /* #define DEBUG */
                   1094: /* #define DEBUGBRENT */
1.203     brouard  1095: /* #define DEBUGLINMIN */
                   1096: /* #define DEBUGHESS */
                   1097: #define DEBUGHESSIJ
1.224     brouard  1098: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard  1099: #define POWELL /* Instead of NLOPT */
1.224     brouard  1100: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard  1101: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                   1102: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.319   ! brouard  1103: /* #define FLATSUP  *//* Suppresses directions where likelihood is flat */
1.126     brouard  1104: 
                   1105: #include <math.h>
                   1106: #include <stdio.h>
                   1107: #include <stdlib.h>
                   1108: #include <string.h>
1.226     brouard  1109: #include <ctype.h>
1.159     brouard  1110: 
                   1111: #ifdef _WIN32
                   1112: #include <io.h>
1.172     brouard  1113: #include <windows.h>
                   1114: #include <tchar.h>
1.159     brouard  1115: #else
1.126     brouard  1116: #include <unistd.h>
1.159     brouard  1117: #endif
1.126     brouard  1118: 
                   1119: #include <limits.h>
                   1120: #include <sys/types.h>
1.171     brouard  1121: 
                   1122: #if defined(__GNUC__)
                   1123: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1124: #endif
                   1125: 
1.126     brouard  1126: #include <sys/stat.h>
                   1127: #include <errno.h>
1.159     brouard  1128: /* extern int errno; */
1.126     brouard  1129: 
1.157     brouard  1130: /* #ifdef LINUX */
                   1131: /* #include <time.h> */
                   1132: /* #include "timeval.h" */
                   1133: /* #else */
                   1134: /* #include <sys/time.h> */
                   1135: /* #endif */
                   1136: 
1.126     brouard  1137: #include <time.h>
                   1138: 
1.136     brouard  1139: #ifdef GSL
                   1140: #include <gsl/gsl_errno.h>
                   1141: #include <gsl/gsl_multimin.h>
                   1142: #endif
                   1143: 
1.167     brouard  1144: 
1.162     brouard  1145: #ifdef NLOPT
                   1146: #include <nlopt.h>
                   1147: typedef struct {
                   1148:   double (* function)(double [] );
                   1149: } myfunc_data ;
                   1150: #endif
                   1151: 
1.126     brouard  1152: /* #include <libintl.h> */
                   1153: /* #define _(String) gettext (String) */
                   1154: 
1.251     brouard  1155: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1156: 
                   1157: #define GNUPLOTPROGRAM "gnuplot"
                   1158: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1159: #define FILENAMELENGTH 132
                   1160: 
                   1161: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1162: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1163: 
1.144     brouard  1164: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1165: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1166: 
                   1167: #define NINTERVMAX 8
1.144     brouard  1168: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1169: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.318     brouard  1170: #define NCOVMAX 30  /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1171: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1172: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1173: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1174: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1175: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1176: /* #define AGESUP 130 */
1.288     brouard  1177: /* #define AGESUP 150 */
                   1178: #define AGESUP 200
1.268     brouard  1179: #define AGEINF 0
1.218     brouard  1180: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1181: #define AGEBASE 40
1.194     brouard  1182: #define AGEOVERFLOW 1.e20
1.164     brouard  1183: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1184: #ifdef _WIN32
                   1185: #define DIRSEPARATOR '\\'
                   1186: #define CHARSEPARATOR "\\"
                   1187: #define ODIRSEPARATOR '/'
                   1188: #else
1.126     brouard  1189: #define DIRSEPARATOR '/'
                   1190: #define CHARSEPARATOR "/"
                   1191: #define ODIRSEPARATOR '\\'
                   1192: #endif
                   1193: 
1.319   ! brouard  1194: /* $Id: imach.c,v 1.318 2022/05/24 08:10:59 brouard Exp $ */
1.126     brouard  1195: /* $State: Exp $ */
1.196     brouard  1196: #include "version.h"
                   1197: char version[]=__IMACH_VERSION__;
1.316     brouard  1198: char copyright[]="May 2022,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2020, Nihon University 2021-202, INED 2000-2022";
1.319   ! brouard  1199: char fullversion[]="$Revision: 1.318 $ $Date: 2022/05/24 08:10:59 $"; 
1.126     brouard  1200: char strstart[80];
                   1201: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1202: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1203: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1204: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1205: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1206: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1207: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1208: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1209: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1210: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1211: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1212: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1213: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1214: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1215: int nsd=0; /**< Total number of single dummy variables (output) */
                   1216: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1217: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1218: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1219: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1220: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1221: int cptcov=0; /* Working variable */
1.290     brouard  1222: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1223: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.302     brouard  1224: int npar=NPARMAX; /* Number of parameters (nlstate+ndeath-1)*nlstate*ncovmodel; */
1.126     brouard  1225: int nlstate=2; /* Number of live states */
                   1226: int ndeath=1; /* Number of dead states */
1.130     brouard  1227: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1228: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1229: int popbased=0;
                   1230: 
                   1231: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1232: int maxwav=0; /* Maxim number of waves */
                   1233: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1234: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1235: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1236:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1237: int mle=1, weightopt=0;
1.126     brouard  1238: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1239: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1240: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1241:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1242: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1243: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1244: 
1.130     brouard  1245: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1246: double **matprod2(); /* test */
1.126     brouard  1247: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1248: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1249: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1250: 
1.136     brouard  1251: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1252: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1253: FILE *ficlog, *ficrespow;
1.130     brouard  1254: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1255: double fretone; /* Only one call to likelihood */
1.130     brouard  1256: long ipmx=0; /* Number of contributions */
1.126     brouard  1257: double sw; /* Sum of weights */
                   1258: char filerespow[FILENAMELENGTH];
                   1259: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1260: FILE *ficresilk;
                   1261: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1262: FILE *ficresprobmorprev;
                   1263: FILE *fichtm, *fichtmcov; /* Html File */
                   1264: FILE *ficreseij;
                   1265: char filerese[FILENAMELENGTH];
                   1266: FILE *ficresstdeij;
                   1267: char fileresstde[FILENAMELENGTH];
                   1268: FILE *ficrescveij;
                   1269: char filerescve[FILENAMELENGTH];
                   1270: FILE  *ficresvij;
                   1271: char fileresv[FILENAMELENGTH];
1.269     brouard  1272: 
1.126     brouard  1273: char title[MAXLINE];
1.234     brouard  1274: char model[MAXLINE]; /**< The model line */
1.217     brouard  1275: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1276: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1277: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1278: char command[FILENAMELENGTH];
                   1279: int  outcmd=0;
                   1280: 
1.217     brouard  1281: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1282: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1283: char filelog[FILENAMELENGTH]; /* Log file */
                   1284: char filerest[FILENAMELENGTH];
                   1285: char fileregp[FILENAMELENGTH];
                   1286: char popfile[FILENAMELENGTH];
                   1287: 
                   1288: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1289: 
1.157     brouard  1290: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1291: /* struct timezone tzp; */
                   1292: /* extern int gettimeofday(); */
                   1293: struct tm tml, *gmtime(), *localtime();
                   1294: 
                   1295: extern time_t time();
                   1296: 
                   1297: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1298: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1299: struct tm tm;
                   1300: 
1.126     brouard  1301: char strcurr[80], strfor[80];
                   1302: 
                   1303: char *endptr;
                   1304: long lval;
                   1305: double dval;
                   1306: 
                   1307: #define NR_END 1
                   1308: #define FREE_ARG char*
                   1309: #define FTOL 1.0e-10
                   1310: 
                   1311: #define NRANSI 
1.240     brouard  1312: #define ITMAX 200
                   1313: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1314: 
                   1315: #define TOL 2.0e-4 
                   1316: 
                   1317: #define CGOLD 0.3819660 
                   1318: #define ZEPS 1.0e-10 
                   1319: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1320: 
                   1321: #define GOLD 1.618034 
                   1322: #define GLIMIT 100.0 
                   1323: #define TINY 1.0e-20 
                   1324: 
                   1325: static double maxarg1,maxarg2;
                   1326: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1327: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1328:   
                   1329: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1330: #define rint(a) floor(a+0.5)
1.166     brouard  1331: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1332: #define mytinydouble 1.0e-16
1.166     brouard  1333: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1334: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1335: /* static double dsqrarg; */
                   1336: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1337: static double sqrarg;
                   1338: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1339: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1340: int agegomp= AGEGOMP;
                   1341: 
                   1342: int imx; 
                   1343: int stepm=1;
                   1344: /* Stepm, step in month: minimum step interpolation*/
                   1345: 
                   1346: int estepm;
                   1347: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1348: 
                   1349: int m,nb;
                   1350: long *num;
1.197     brouard  1351: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1352: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1353:                   covariate for which somebody answered excluding 
                   1354:                   undefined. Usually 2: 0 and 1. */
                   1355: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1356:                             covariate for which somebody answered including 
                   1357:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1358: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1359: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1360: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1361: double *ageexmed,*agecens;
                   1362: double dateintmean=0;
1.296     brouard  1363:   double anprojd, mprojd, jprojd; /* For eventual projections */
                   1364:   double anprojf, mprojf, jprojf;
1.126     brouard  1365: 
1.296     brouard  1366:   double anbackd, mbackd, jbackd; /* For eventual backprojections */
                   1367:   double anbackf, mbackf, jbackf;
                   1368:   double jintmean,mintmean,aintmean;  
1.126     brouard  1369: double *weight;
                   1370: int **s; /* Status */
1.141     brouard  1371: double *agedc;
1.145     brouard  1372: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1373:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1374:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1375: double **coqvar; /* Fixed quantitative covariate nqv */
                   1376: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1377: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1378: double  idx; 
                   1379: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.319   ! brouard  1380: /* Some documentation */
        !          1381:       /*   Design original data
        !          1382:        *  V1   V2   V3   V4  V5  V6  V7  V8  Weight ddb ddth d1st s1 V9 V10 V11 V12 s2 V9 V10 V11 V12 
        !          1383:        *  <          ncovcol=6   >   nqv=2 (V7 V8)                   dv dv  dv  qtv    dv dv  dvv qtv
        !          1384:        *                                                             ntv=3     nqtv=1
        !          1385:        *  cptcovn number of covariates (not including constant and age) = # of + plus 1 = 10+1=11
        !          1386:        * For time varying covariate, quanti or dummies
        !          1387:        *       cotqvar[wav][iv(1 to nqtv)][i]= [1][12][i]=(V12) quanti
        !          1388:        *       cotvar[wav][ntv+iv][i]= [3+(1 to nqtv)][i]=(V12) quanti
        !          1389:        *       cotvar[wav][iv(1 to ntv)][i]= [1][1][i]=(V9) dummies at wav 1
        !          1390:        *       cotvar[wav][iv(1 to ntv)][i]= [1][2][i]=(V10) dummies at wav 1
        !          1391:        *       covar[k,i], value of kth fixed covariate dummy or quanti :
        !          1392:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
        !          1393:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8 + V9 + V9*age + V10
        !          1394:        *   k=  1    2      3       4     5       6      7        8   9     10       11 
        !          1395:        */
        !          1396: /* According to the model, more columns can be added to covar by the product of covariates */
1.318     brouard  1397: /* ncovcol=1(Males=0 Females=1) nqv=1(raedyrs) ntv=2(withoutiadl=0 withiadl=1, witoutadl=0 withoutadl=1) nqtv=1(bmi) nlstate=3 ndeath=1
                   1398:   # States 1=Coresidence, 2 Living alone, 3 Institution
                   1399:   # V1=sex, V2=raedyrs Quant Fixed, State=livarnb4..livarnb11, V3=iadl4..iald11, V4=adlw4..adlw11, V5=r4bmi..r11bmi
                   1400: */
1.319   ! brouard  1401: /*             V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
        !          1402: /*    k        1  2   3   4     5    6    7     8    9 */
        !          1403: /*Typevar[k]=  0  0   0   2     1    0    2     1    0 *//*0 for simple covariate (dummy, quantitative,*/
        !          1404:                                                          /* fixed or varying), 1 for age product, 2 for*/
        !          1405:                                                          /* product */
        !          1406: /*Dummy[k]=    1  0   0   1     3    1    1     2    0 *//*Dummy[k] 0=dummy (0 1), 1 quantitative */
        !          1407:                                                          /*(single or product without age), 2 dummy*/
        !          1408:                                                          /* with age product, 3 quant with age product*/
        !          1409: /*Tvar[k]=     5  4   3   6     5    2    7     1    1 */
        !          1410: /*    nsd         1   2                              3 */ /* Counting single dummies covar fixed or tv */
        !          1411: /*TvarsD[nsd]     4   3                              1 */ /* ID of single dummy cova fixed or timevary*/
        !          1412: /*TvarsDind[k]    2   3                              9 */ /* position K of single dummy cova */
        !          1413: /*    nsq      1                     2                 */ /* Counting single quantit tv */
        !          1414: /* TvarsQ[k]   5                     2                 */ /* Number of single quantitative cova */
        !          1415: /* TvarsQind   1                     6                 */ /* position K of single quantitative cova */
        !          1416: /* Tprod[i]=k             1               2            */ /* Position in model of the ith prod without age */
        !          1417: /* cptcovage                    1               2      */ /* Counting cov*age in the model equation */
        !          1418: /* Tage[cptcovage]=k            5               8      */ /* Position in the model of ith cov*age */
        !          1419: /* Tvard[1][1]@4={4,3,1,2}    V4*V3 V1*V2              */ /* Position in model of the ith prod without age */
        !          1420: /* TvarF TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  ID of fixed covariates or product V2, V1*V2, V1 */
        !          1421: /* TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, TvarFind[3]=9 *//* Inverse V2(6) is first fixed (single or prod)  */
1.234     brouard  1422: /* Type                    */
                   1423: /* V         1  2  3  4  5 */
                   1424: /*           F  F  V  V  V */
                   1425: /*           D  Q  D  D  Q */
                   1426: /*                         */
                   1427: int *TvarsD;
                   1428: int *TvarsDind;
                   1429: int *TvarsQ;
                   1430: int *TvarsQind;
                   1431: 
1.318     brouard  1432: #define MAXRESULTLINESPONE 10+1
1.235     brouard  1433: int nresult=0;
1.258     brouard  1434: int parameterline=0; /* # of the parameter (type) line */
1.318     brouard  1435: int TKresult[MAXRESULTLINESPONE];
                   1436: int Tresult[MAXRESULTLINESPONE][NCOVMAX];/* For dummy variable , value (output) */
                   1437: int Tinvresult[MAXRESULTLINESPONE][NCOVMAX];/* For dummy variable , value (output) */
                   1438: int Tvresult[MAXRESULTLINESPONE][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1439: double Tqresult[MAXRESULTLINESPONE][NCOVMAX]; /* For quantitative variable , value (output) */
                   1440: double Tqinvresult[MAXRESULTLINESPONE][NCOVMAX]; /* For quantitative variable , value (output) */
                   1441: int Tvqresult[MAXRESULTLINESPONE][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1442: 
                   1443: /* ncovcol=1(Males=0 Females=1) nqv=1(raedyrs) ntv=2(withoutiadl=0 withiadl=1, witoutadl=0 withoutadl=1) nqtv=1(bmi) nlstate=3 ndeath=1
                   1444:   # States 1=Coresidence, 2 Living alone, 3 Institution
                   1445:   # V1=sex, V2=raedyrs Quant Fixed, State=livarnb4..livarnb11, V3=iadl4..iald11, V4=adlw4..adlw11, V5=r4bmi..r11bmi
                   1446: */
1.234     brouard  1447: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1448: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1449: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1450: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1451: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1452: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1453: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1454: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1455: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1456: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1457: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1458: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1459: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1460: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1461: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1462: 
1.230     brouard  1463: int *Tvarsel; /**< Selected covariates for output */
                   1464: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1465: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1466: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1467: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1468: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1469: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1470: int *Tage;
1.227     brouard  1471: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1472: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1473: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1474: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1475: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1476: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1477: int **Tvard;
                   1478: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1479: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1480: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1481:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1482:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1483: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1484: double *lsurv, *lpop, *tpop;
                   1485: 
1.231     brouard  1486: #define FD 1; /* Fixed dummy covariate */
                   1487: #define FQ 2; /* Fixed quantitative covariate */
                   1488: #define FP 3; /* Fixed product covariate */
                   1489: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1490: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1491: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1492: #define VD 10; /* Varying dummy covariate */
                   1493: #define VQ 11; /* Varying quantitative covariate */
                   1494: #define VP 12; /* Varying product covariate */
                   1495: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1496: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1497: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1498: #define APFD 16; /* Age product * fixed dummy covariate */
                   1499: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1500: #define APVD 18; /* Age product * varying dummy covariate */
                   1501: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1502: 
                   1503: #define FTYPE 1; /* Fixed covariate */
                   1504: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1505: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1506: 
                   1507: struct kmodel{
                   1508:        int maintype; /* main type */
                   1509:        int subtype; /* subtype */
                   1510: };
                   1511: struct kmodel modell[NCOVMAX];
                   1512: 
1.143     brouard  1513: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1514: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1515: 
                   1516: /**************** split *************************/
                   1517: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1518: {
                   1519:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1520:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1521:   */ 
                   1522:   char *ss;                            /* pointer */
1.186     brouard  1523:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1524: 
                   1525:   l1 = strlen(path );                  /* length of path */
                   1526:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1527:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1528:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1529:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1530:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1531:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1532:     /* get current working directory */
                   1533:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1534: #ifdef WIN32
                   1535:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1536: #else
                   1537:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1538: #endif
1.126     brouard  1539:       return( GLOCK_ERROR_GETCWD );
                   1540:     }
                   1541:     /* got dirc from getcwd*/
                   1542:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1543:   } else {                             /* strip directory from path */
1.126     brouard  1544:     ss++;                              /* after this, the filename */
                   1545:     l2 = strlen( ss );                 /* length of filename */
                   1546:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1547:     strcpy( name, ss );                /* save file name */
                   1548:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1549:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1550:     printf(" DIRC2 = %s \n",dirc);
                   1551:   }
                   1552:   /* We add a separator at the end of dirc if not exists */
                   1553:   l1 = strlen( dirc );                 /* length of directory */
                   1554:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1555:     dirc[l1] =  DIRSEPARATOR;
                   1556:     dirc[l1+1] = 0; 
                   1557:     printf(" DIRC3 = %s \n",dirc);
                   1558:   }
                   1559:   ss = strrchr( name, '.' );           /* find last / */
                   1560:   if (ss >0){
                   1561:     ss++;
                   1562:     strcpy(ext,ss);                    /* save extension */
                   1563:     l1= strlen( name);
                   1564:     l2= strlen(ss)+1;
                   1565:     strncpy( finame, name, l1-l2);
                   1566:     finame[l1-l2]= 0;
                   1567:   }
                   1568: 
                   1569:   return( 0 );                         /* we're done */
                   1570: }
                   1571: 
                   1572: 
                   1573: /******************************************/
                   1574: 
                   1575: void replace_back_to_slash(char *s, char*t)
                   1576: {
                   1577:   int i;
                   1578:   int lg=0;
                   1579:   i=0;
                   1580:   lg=strlen(t);
                   1581:   for(i=0; i<= lg; i++) {
                   1582:     (s[i] = t[i]);
                   1583:     if (t[i]== '\\') s[i]='/';
                   1584:   }
                   1585: }
                   1586: 
1.132     brouard  1587: char *trimbb(char *out, char *in)
1.137     brouard  1588: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1589:   char *s;
                   1590:   s=out;
                   1591:   while (*in != '\0'){
1.137     brouard  1592:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1593:       in++;
                   1594:     }
                   1595:     *out++ = *in++;
                   1596:   }
                   1597:   *out='\0';
                   1598:   return s;
                   1599: }
                   1600: 
1.187     brouard  1601: /* char *substrchaine(char *out, char *in, char *chain) */
                   1602: /* { */
                   1603: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1604: /*   char *s, *t; */
                   1605: /*   t=in;s=out; */
                   1606: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1607: /*     *out++ = *in++; */
                   1608: /*   } */
                   1609: 
                   1610: /*   /\* *in matches *chain *\/ */
                   1611: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1612: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1613: /*   } */
                   1614: /*   in--; chain--; */
                   1615: /*   while ( (*in != '\0')){ */
                   1616: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1617: /*     *out++ = *in++; */
                   1618: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1619: /*   } */
                   1620: /*   *out='\0'; */
                   1621: /*   out=s; */
                   1622: /*   return out; */
                   1623: /* } */
                   1624: char *substrchaine(char *out, char *in, char *chain)
                   1625: {
                   1626:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1627:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1628: 
                   1629:   char *strloc;
                   1630: 
                   1631:   strcpy (out, in); 
                   1632:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1633:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1634:   if(strloc != NULL){ 
                   1635:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1636:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1637:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1638:   }
                   1639:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1640:   return out;
                   1641: }
                   1642: 
                   1643: 
1.145     brouard  1644: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1645: {
1.187     brouard  1646:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1647:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.310     brouard  1648:      gives alocc="abcdef" and blocc="ghi2j".
1.145     brouard  1649:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1650:   */
1.160     brouard  1651:   char *s, *t;
1.145     brouard  1652:   t=in;s=in;
                   1653:   while ((*in != occ) && (*in != '\0')){
                   1654:     *alocc++ = *in++;
                   1655:   }
                   1656:   if( *in == occ){
                   1657:     *(alocc)='\0';
                   1658:     s=++in;
                   1659:   }
                   1660:  
                   1661:   if (s == t) {/* occ not found */
                   1662:     *(alocc-(in-s))='\0';
                   1663:     in=s;
                   1664:   }
                   1665:   while ( *in != '\0'){
                   1666:     *blocc++ = *in++;
                   1667:   }
                   1668: 
                   1669:   *blocc='\0';
                   1670:   return t;
                   1671: }
1.137     brouard  1672: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1673: {
1.187     brouard  1674:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1675:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1676:      gives blocc="abcdef2ghi" and alocc="j".
                   1677:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1678:   */
                   1679:   char *s, *t;
                   1680:   t=in;s=in;
                   1681:   while (*in != '\0'){
                   1682:     while( *in == occ){
                   1683:       *blocc++ = *in++;
                   1684:       s=in;
                   1685:     }
                   1686:     *blocc++ = *in++;
                   1687:   }
                   1688:   if (s == t) /* occ not found */
                   1689:     *(blocc-(in-s))='\0';
                   1690:   else
                   1691:     *(blocc-(in-s)-1)='\0';
                   1692:   in=s;
                   1693:   while ( *in != '\0'){
                   1694:     *alocc++ = *in++;
                   1695:   }
                   1696: 
                   1697:   *alocc='\0';
                   1698:   return s;
                   1699: }
                   1700: 
1.126     brouard  1701: int nbocc(char *s, char occ)
                   1702: {
                   1703:   int i,j=0;
                   1704:   int lg=20;
                   1705:   i=0;
                   1706:   lg=strlen(s);
                   1707:   for(i=0; i<= lg; i++) {
1.234     brouard  1708:     if  (s[i] == occ ) j++;
1.126     brouard  1709:   }
                   1710:   return j;
                   1711: }
                   1712: 
1.137     brouard  1713: /* void cutv(char *u,char *v, char*t, char occ) */
                   1714: /* { */
                   1715: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1716: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1717: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1718: /*   int i,lg,j,p=0; */
                   1719: /*   i=0; */
                   1720: /*   lg=strlen(t); */
                   1721: /*   for(j=0; j<=lg-1; j++) { */
                   1722: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1723: /*   } */
1.126     brouard  1724: 
1.137     brouard  1725: /*   for(j=0; j<p; j++) { */
                   1726: /*     (u[j] = t[j]); */
                   1727: /*   } */
                   1728: /*      u[p]='\0'; */
1.126     brouard  1729: 
1.137     brouard  1730: /*    for(j=0; j<= lg; j++) { */
                   1731: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1732: /*   } */
                   1733: /* } */
1.126     brouard  1734: 
1.160     brouard  1735: #ifdef _WIN32
                   1736: char * strsep(char **pp, const char *delim)
                   1737: {
                   1738:   char *p, *q;
                   1739:          
                   1740:   if ((p = *pp) == NULL)
                   1741:     return 0;
                   1742:   if ((q = strpbrk (p, delim)) != NULL)
                   1743:   {
                   1744:     *pp = q + 1;
                   1745:     *q = '\0';
                   1746:   }
                   1747:   else
                   1748:     *pp = 0;
                   1749:   return p;
                   1750: }
                   1751: #endif
                   1752: 
1.126     brouard  1753: /********************** nrerror ********************/
                   1754: 
                   1755: void nrerror(char error_text[])
                   1756: {
                   1757:   fprintf(stderr,"ERREUR ...\n");
                   1758:   fprintf(stderr,"%s\n",error_text);
                   1759:   exit(EXIT_FAILURE);
                   1760: }
                   1761: /*********************** vector *******************/
                   1762: double *vector(int nl, int nh)
                   1763: {
                   1764:   double *v;
                   1765:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1766:   if (!v) nrerror("allocation failure in vector");
                   1767:   return v-nl+NR_END;
                   1768: }
                   1769: 
                   1770: /************************ free vector ******************/
                   1771: void free_vector(double*v, int nl, int nh)
                   1772: {
                   1773:   free((FREE_ARG)(v+nl-NR_END));
                   1774: }
                   1775: 
                   1776: /************************ivector *******************************/
                   1777: int *ivector(long nl,long nh)
                   1778: {
                   1779:   int *v;
                   1780:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1781:   if (!v) nrerror("allocation failure in ivector");
                   1782:   return v-nl+NR_END;
                   1783: }
                   1784: 
                   1785: /******************free ivector **************************/
                   1786: void free_ivector(int *v, long nl, long nh)
                   1787: {
                   1788:   free((FREE_ARG)(v+nl-NR_END));
                   1789: }
                   1790: 
                   1791: /************************lvector *******************************/
                   1792: long *lvector(long nl,long nh)
                   1793: {
                   1794:   long *v;
                   1795:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1796:   if (!v) nrerror("allocation failure in ivector");
                   1797:   return v-nl+NR_END;
                   1798: }
                   1799: 
                   1800: /******************free lvector **************************/
                   1801: void free_lvector(long *v, long nl, long nh)
                   1802: {
                   1803:   free((FREE_ARG)(v+nl-NR_END));
                   1804: }
                   1805: 
                   1806: /******************* imatrix *******************************/
                   1807: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1808:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1809: { 
                   1810:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1811:   int **m; 
                   1812:   
                   1813:   /* allocate pointers to rows */ 
                   1814:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1815:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1816:   m += NR_END; 
                   1817:   m -= nrl; 
                   1818:   
                   1819:   
                   1820:   /* allocate rows and set pointers to them */ 
                   1821:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1822:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1823:   m[nrl] += NR_END; 
                   1824:   m[nrl] -= ncl; 
                   1825:   
                   1826:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1827:   
                   1828:   /* return pointer to array of pointers to rows */ 
                   1829:   return m; 
                   1830: } 
                   1831: 
                   1832: /****************** free_imatrix *************************/
                   1833: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1834:       int **m;
                   1835:       long nch,ncl,nrh,nrl; 
                   1836:      /* free an int matrix allocated by imatrix() */ 
                   1837: { 
                   1838:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1839:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1840: } 
                   1841: 
                   1842: /******************* matrix *******************************/
                   1843: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1844: {
                   1845:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1846:   double **m;
                   1847: 
                   1848:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1849:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1850:   m += NR_END;
                   1851:   m -= nrl;
                   1852: 
                   1853:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1854:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1855:   m[nrl] += NR_END;
                   1856:   m[nrl] -= ncl;
                   1857: 
                   1858:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1859:   return m;
1.145     brouard  1860:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1861: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1862: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1863:    */
                   1864: }
                   1865: 
                   1866: /*************************free matrix ************************/
                   1867: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1868: {
                   1869:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1870:   free((FREE_ARG)(m+nrl-NR_END));
                   1871: }
                   1872: 
                   1873: /******************* ma3x *******************************/
                   1874: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1875: {
                   1876:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1877:   double ***m;
                   1878: 
                   1879:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1880:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1881:   m += NR_END;
                   1882:   m -= nrl;
                   1883: 
                   1884:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1885:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1886:   m[nrl] += NR_END;
                   1887:   m[nrl] -= ncl;
                   1888: 
                   1889:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1890: 
                   1891:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1892:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1893:   m[nrl][ncl] += NR_END;
                   1894:   m[nrl][ncl] -= nll;
                   1895:   for (j=ncl+1; j<=nch; j++) 
                   1896:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1897:   
                   1898:   for (i=nrl+1; i<=nrh; i++) {
                   1899:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1900:     for (j=ncl+1; j<=nch; j++) 
                   1901:       m[i][j]=m[i][j-1]+nlay;
                   1902:   }
                   1903:   return m; 
                   1904:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1905:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1906:   */
                   1907: }
                   1908: 
                   1909: /*************************free ma3x ************************/
                   1910: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1911: {
                   1912:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1913:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1914:   free((FREE_ARG)(m+nrl-NR_END));
                   1915: }
                   1916: 
                   1917: /*************** function subdirf ***********/
                   1918: char *subdirf(char fileres[])
                   1919: {
                   1920:   /* Caution optionfilefiname is hidden */
                   1921:   strcpy(tmpout,optionfilefiname);
                   1922:   strcat(tmpout,"/"); /* Add to the right */
                   1923:   strcat(tmpout,fileres);
                   1924:   return tmpout;
                   1925: }
                   1926: 
                   1927: /*************** function subdirf2 ***********/
                   1928: char *subdirf2(char fileres[], char *preop)
                   1929: {
1.314     brouard  1930:   /* Example subdirf2(optionfilefiname,"FB_") with optionfilefiname="texte", result="texte/FB_texte"
                   1931:  Errors in subdirf, 2, 3 while printing tmpout is
1.315     brouard  1932:  rewritten within the same printf. Workaround: many printfs */
1.126     brouard  1933:   /* Caution optionfilefiname is hidden */
                   1934:   strcpy(tmpout,optionfilefiname);
                   1935:   strcat(tmpout,"/");
                   1936:   strcat(tmpout,preop);
                   1937:   strcat(tmpout,fileres);
                   1938:   return tmpout;
                   1939: }
                   1940: 
                   1941: /*************** function subdirf3 ***********/
                   1942: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1943: {
                   1944:   
                   1945:   /* Caution optionfilefiname is hidden */
                   1946:   strcpy(tmpout,optionfilefiname);
                   1947:   strcat(tmpout,"/");
                   1948:   strcat(tmpout,preop);
                   1949:   strcat(tmpout,preop2);
                   1950:   strcat(tmpout,fileres);
                   1951:   return tmpout;
                   1952: }
1.213     brouard  1953:  
                   1954: /*************** function subdirfext ***********/
                   1955: char *subdirfext(char fileres[], char *preop, char *postop)
                   1956: {
                   1957:   
                   1958:   strcpy(tmpout,preop);
                   1959:   strcat(tmpout,fileres);
                   1960:   strcat(tmpout,postop);
                   1961:   return tmpout;
                   1962: }
1.126     brouard  1963: 
1.213     brouard  1964: /*************** function subdirfext3 ***********/
                   1965: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1966: {
                   1967:   
                   1968:   /* Caution optionfilefiname is hidden */
                   1969:   strcpy(tmpout,optionfilefiname);
                   1970:   strcat(tmpout,"/");
                   1971:   strcat(tmpout,preop);
                   1972:   strcat(tmpout,fileres);
                   1973:   strcat(tmpout,postop);
                   1974:   return tmpout;
                   1975: }
                   1976:  
1.162     brouard  1977: char *asc_diff_time(long time_sec, char ascdiff[])
                   1978: {
                   1979:   long sec_left, days, hours, minutes;
                   1980:   days = (time_sec) / (60*60*24);
                   1981:   sec_left = (time_sec) % (60*60*24);
                   1982:   hours = (sec_left) / (60*60) ;
                   1983:   sec_left = (sec_left) %(60*60);
                   1984:   minutes = (sec_left) /60;
                   1985:   sec_left = (sec_left) % (60);
                   1986:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1987:   return ascdiff;
                   1988: }
                   1989: 
1.126     brouard  1990: /***************** f1dim *************************/
                   1991: extern int ncom; 
                   1992: extern double *pcom,*xicom;
                   1993: extern double (*nrfunc)(double []); 
                   1994:  
                   1995: double f1dim(double x) 
                   1996: { 
                   1997:   int j; 
                   1998:   double f;
                   1999:   double *xt; 
                   2000:  
                   2001:   xt=vector(1,ncom); 
                   2002:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   2003:   f=(*nrfunc)(xt); 
                   2004:   free_vector(xt,1,ncom); 
                   2005:   return f; 
                   2006: } 
                   2007: 
                   2008: /*****************brent *************************/
                   2009: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  2010: {
                   2011:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   2012:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   2013:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   2014:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   2015:    * returned function value. 
                   2016:   */
1.126     brouard  2017:   int iter; 
                   2018:   double a,b,d,etemp;
1.159     brouard  2019:   double fu=0,fv,fw,fx;
1.164     brouard  2020:   double ftemp=0.;
1.126     brouard  2021:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   2022:   double e=0.0; 
                   2023:  
                   2024:   a=(ax < cx ? ax : cx); 
                   2025:   b=(ax > cx ? ax : cx); 
                   2026:   x=w=v=bx; 
                   2027:   fw=fv=fx=(*f)(x); 
                   2028:   for (iter=1;iter<=ITMAX;iter++) { 
                   2029:     xm=0.5*(a+b); 
                   2030:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   2031:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   2032:     printf(".");fflush(stdout);
                   2033:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  2034: #ifdef DEBUGBRENT
1.126     brouard  2035:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   2036:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   2037:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   2038: #endif
                   2039:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   2040:       *xmin=x; 
                   2041:       return fx; 
                   2042:     } 
                   2043:     ftemp=fu;
                   2044:     if (fabs(e) > tol1) { 
                   2045:       r=(x-w)*(fx-fv); 
                   2046:       q=(x-v)*(fx-fw); 
                   2047:       p=(x-v)*q-(x-w)*r; 
                   2048:       q=2.0*(q-r); 
                   2049:       if (q > 0.0) p = -p; 
                   2050:       q=fabs(q); 
                   2051:       etemp=e; 
                   2052:       e=d; 
                   2053:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  2054:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  2055:       else { 
1.224     brouard  2056:                                d=p/q; 
                   2057:                                u=x+d; 
                   2058:                                if (u-a < tol2 || b-u < tol2) 
                   2059:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  2060:       } 
                   2061:     } else { 
                   2062:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   2063:     } 
                   2064:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   2065:     fu=(*f)(u); 
                   2066:     if (fu <= fx) { 
                   2067:       if (u >= x) a=x; else b=x; 
                   2068:       SHFT(v,w,x,u) 
1.183     brouard  2069:       SHFT(fv,fw,fx,fu) 
                   2070:     } else { 
                   2071:       if (u < x) a=u; else b=u; 
                   2072:       if (fu <= fw || w == x) { 
1.224     brouard  2073:                                v=w; 
                   2074:                                w=u; 
                   2075:                                fv=fw; 
                   2076:                                fw=fu; 
1.183     brouard  2077:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  2078:                                v=u; 
                   2079:                                fv=fu; 
1.183     brouard  2080:       } 
                   2081:     } 
1.126     brouard  2082:   } 
                   2083:   nrerror("Too many iterations in brent"); 
                   2084:   *xmin=x; 
                   2085:   return fx; 
                   2086: } 
                   2087: 
                   2088: /****************** mnbrak ***********************/
                   2089: 
                   2090: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   2091:            double (*func)(double)) 
1.183     brouard  2092: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   2093: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   2094: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   2095: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   2096:    */
1.126     brouard  2097:   double ulim,u,r,q, dum;
                   2098:   double fu; 
1.187     brouard  2099: 
                   2100:   double scale=10.;
                   2101:   int iterscale=0;
                   2102: 
                   2103:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   2104:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   2105: 
                   2106: 
                   2107:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   2108:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   2109:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   2110:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   2111:   /* } */
                   2112: 
1.126     brouard  2113:   if (*fb > *fa) { 
                   2114:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  2115:     SHFT(dum,*fb,*fa,dum) 
                   2116:   } 
1.126     brouard  2117:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   2118:   *fc=(*func)(*cx); 
1.183     brouard  2119: #ifdef DEBUG
1.224     brouard  2120:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   2121:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  2122: #endif
1.224     brouard  2123:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  2124:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  2125:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  2126:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  2127:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   2128:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   2129:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  2130:       fu=(*func)(u); 
1.163     brouard  2131: #ifdef DEBUG
                   2132:       /* f(x)=A(x-u)**2+f(u) */
                   2133:       double A, fparabu; 
                   2134:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2135:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  2136:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   2137:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  2138:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   2139:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   2140:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   2141:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  2142: #endif 
1.184     brouard  2143: #ifdef MNBRAKORIGINAL
1.183     brouard  2144: #else
1.191     brouard  2145: /*       if (fu > *fc) { */
                   2146: /* #ifdef DEBUG */
                   2147: /*       printf("mnbrak4  fu > fc \n"); */
                   2148: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   2149: /* #endif */
                   2150: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   2151: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   2152: /*     dum=u; /\* Shifting c and u *\/ */
                   2153: /*     u = *cx; */
                   2154: /*     *cx = dum; */
                   2155: /*     dum = fu; */
                   2156: /*     fu = *fc; */
                   2157: /*     *fc =dum; */
                   2158: /*       } else { /\* end *\/ */
                   2159: /* #ifdef DEBUG */
                   2160: /*       printf("mnbrak3  fu < fc \n"); */
                   2161: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2162: /* #endif */
                   2163: /*     dum=u; /\* Shifting c and u *\/ */
                   2164: /*     u = *cx; */
                   2165: /*     *cx = dum; */
                   2166: /*     dum = fu; */
                   2167: /*     fu = *fc; */
                   2168: /*     *fc =dum; */
                   2169: /*       } */
1.224     brouard  2170: #ifdef DEBUGMNBRAK
                   2171:                 double A, fparabu; 
                   2172:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2173:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2174:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2175:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2176: #endif
1.191     brouard  2177:       dum=u; /* Shifting c and u */
                   2178:       u = *cx;
                   2179:       *cx = dum;
                   2180:       dum = fu;
                   2181:       fu = *fc;
                   2182:       *fc =dum;
1.183     brouard  2183: #endif
1.162     brouard  2184:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2185: #ifdef DEBUG
1.224     brouard  2186:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2187:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2188: #endif
1.126     brouard  2189:       fu=(*func)(u); 
                   2190:       if (fu < *fc) { 
1.183     brouard  2191: #ifdef DEBUG
1.224     brouard  2192:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2193:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2194: #endif
                   2195:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2196:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2197: #ifdef DEBUG
                   2198:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2199: #endif
                   2200:       } 
1.162     brouard  2201:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2202: #ifdef DEBUG
1.224     brouard  2203:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2204:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2205: #endif
1.126     brouard  2206:       u=ulim; 
                   2207:       fu=(*func)(u); 
1.183     brouard  2208:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2209: #ifdef DEBUG
1.224     brouard  2210:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2211:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2212: #endif
1.126     brouard  2213:       u=(*cx)+GOLD*(*cx-*bx); 
                   2214:       fu=(*func)(u); 
1.224     brouard  2215: #ifdef DEBUG
                   2216:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2217:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2218: #endif
1.183     brouard  2219:     } /* end tests */
1.126     brouard  2220:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2221:     SHFT(*fa,*fb,*fc,fu) 
                   2222: #ifdef DEBUG
1.224     brouard  2223:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2224:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2225: #endif
                   2226:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2227: } 
                   2228: 
                   2229: /*************** linmin ************************/
1.162     brouard  2230: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2231: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2232: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2233: the value of func at the returned location p . This is actually all accomplished by calling the
                   2234: routines mnbrak and brent .*/
1.126     brouard  2235: int ncom; 
                   2236: double *pcom,*xicom;
                   2237: double (*nrfunc)(double []); 
                   2238:  
1.224     brouard  2239: #ifdef LINMINORIGINAL
1.126     brouard  2240: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2241: #else
                   2242: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2243: #endif
1.126     brouard  2244: { 
                   2245:   double brent(double ax, double bx, double cx, 
                   2246:               double (*f)(double), double tol, double *xmin); 
                   2247:   double f1dim(double x); 
                   2248:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2249:              double *fc, double (*func)(double)); 
                   2250:   int j; 
                   2251:   double xx,xmin,bx,ax; 
                   2252:   double fx,fb,fa;
1.187     brouard  2253: 
1.203     brouard  2254: #ifdef LINMINORIGINAL
                   2255: #else
                   2256:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2257: #endif
                   2258:   
1.126     brouard  2259:   ncom=n; 
                   2260:   pcom=vector(1,n); 
                   2261:   xicom=vector(1,n); 
                   2262:   nrfunc=func; 
                   2263:   for (j=1;j<=n;j++) { 
                   2264:     pcom[j]=p[j]; 
1.202     brouard  2265:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2266:   } 
1.187     brouard  2267: 
1.203     brouard  2268: #ifdef LINMINORIGINAL
                   2269:   xx=1.;
                   2270: #else
                   2271:   axs=0.0;
                   2272:   xxs=1.;
                   2273:   do{
                   2274:     xx= xxs;
                   2275: #endif
1.187     brouard  2276:     ax=0.;
                   2277:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2278:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2279:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2280:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2281:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2282:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2283:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2284: #ifdef LINMINORIGINAL
                   2285: #else
                   2286:     if (fx != fx){
1.224     brouard  2287:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2288:                        printf("|");
                   2289:                        fprintf(ficlog,"|");
1.203     brouard  2290: #ifdef DEBUGLINMIN
1.224     brouard  2291:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2292: #endif
                   2293:     }
1.224     brouard  2294:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2295: #endif
                   2296:   
1.191     brouard  2297: #ifdef DEBUGLINMIN
                   2298:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2299:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2300: #endif
1.224     brouard  2301: #ifdef LINMINORIGINAL
                   2302: #else
1.317     brouard  2303:   if(fb == fx){ /* Flat function in the direction */
                   2304:     xmin=xx;
1.224     brouard  2305:     *flat=1;
1.317     brouard  2306:   }else{
1.224     brouard  2307:     *flat=0;
                   2308: #endif
                   2309:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2310:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2311:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2312:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2313:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2314:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2315: #ifdef DEBUG
1.224     brouard  2316:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2317:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2318: #endif
                   2319: #ifdef LINMINORIGINAL
                   2320: #else
                   2321:                        }
1.126     brouard  2322: #endif
1.191     brouard  2323: #ifdef DEBUGLINMIN
                   2324:   printf("linmin end ");
1.202     brouard  2325:   fprintf(ficlog,"linmin end ");
1.191     brouard  2326: #endif
1.126     brouard  2327:   for (j=1;j<=n;j++) { 
1.203     brouard  2328: #ifdef LINMINORIGINAL
                   2329:     xi[j] *= xmin; 
                   2330: #else
                   2331: #ifdef DEBUGLINMIN
                   2332:     if(xxs <1.0)
                   2333:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2334: #endif
                   2335:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2336: #ifdef DEBUGLINMIN
                   2337:     if(xxs <1.0)
                   2338:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2339: #endif
                   2340: #endif
1.187     brouard  2341:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2342:   } 
1.191     brouard  2343: #ifdef DEBUGLINMIN
1.203     brouard  2344:   printf("\n");
1.191     brouard  2345:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2346:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2347:   for (j=1;j<=n;j++) { 
1.202     brouard  2348:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2349:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2350:     if(j % ncovmodel == 0){
1.191     brouard  2351:       printf("\n");
1.202     brouard  2352:       fprintf(ficlog,"\n");
                   2353:     }
1.191     brouard  2354:   }
1.203     brouard  2355: #else
1.191     brouard  2356: #endif
1.126     brouard  2357:   free_vector(xicom,1,n); 
                   2358:   free_vector(pcom,1,n); 
                   2359: } 
                   2360: 
                   2361: 
                   2362: /*************** powell ************************/
1.162     brouard  2363: /*
1.317     brouard  2364: Minimization of a function func of n variables. Input consists in an initial starting point
                   2365: p[1..n] ; an initial matrix xi[1..n][1..n]  whose columns contain the initial set of di-
                   2366: rections (usually the n unit vectors); and ftol, the fractional tolerance in the function value
                   2367: such that failure to decrease by more than this amount in one iteration signals doneness. On
1.162     brouard  2368: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2369: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2370:  */
1.224     brouard  2371: #ifdef LINMINORIGINAL
                   2372: #else
                   2373:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2374:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2375: #endif
1.126     brouard  2376: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2377:            double (*func)(double [])) 
                   2378: { 
1.224     brouard  2379: #ifdef LINMINORIGINAL
                   2380:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2381:              double (*func)(double [])); 
1.224     brouard  2382: #else 
1.241     brouard  2383:  void linmin(double p[], double xi[], int n, double *fret,
                   2384:             double (*func)(double []),int *flat); 
1.224     brouard  2385: #endif
1.239     brouard  2386:  int i,ibig,j,jk,k; 
1.126     brouard  2387:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2388:   double directest;
1.126     brouard  2389:   double fp,fptt;
                   2390:   double *xits;
                   2391:   int niterf, itmp;
                   2392: 
                   2393:   pt=vector(1,n); 
                   2394:   ptt=vector(1,n); 
                   2395:   xit=vector(1,n); 
                   2396:   xits=vector(1,n); 
                   2397:   *fret=(*func)(p); 
                   2398:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2399:   rcurr_time = time(NULL);  
1.126     brouard  2400:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2401:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2402:     ibig=0; 
                   2403:     del=0.0; 
1.157     brouard  2404:     rlast_time=rcurr_time;
                   2405:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2406:     rcurr_time = time(NULL);  
                   2407:     curr_time = *localtime(&rcurr_time);
                   2408:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2409:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2410: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2411:     for (i=1;i<=n;i++) {
1.126     brouard  2412:       fprintf(ficrespow," %.12lf", p[i]);
                   2413:     }
1.239     brouard  2414:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2415:     printf("\n#model=  1      +     age ");
                   2416:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2417:     if(nagesqr==1){
1.241     brouard  2418:        printf("  + age*age  ");
                   2419:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2420:     }
                   2421:     for(j=1;j <=ncovmodel-2;j++){
                   2422:       if(Typevar[j]==0) {
                   2423:        printf("  +      V%d  ",Tvar[j]);
                   2424:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2425:       }else if(Typevar[j]==1) {
                   2426:        printf("  +    V%d*age ",Tvar[j]);
                   2427:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2428:       }else if(Typevar[j]==2) {
                   2429:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2430:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2431:       }
                   2432:     }
1.126     brouard  2433:     printf("\n");
1.239     brouard  2434: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2435: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2436:     fprintf(ficlog,"\n");
1.239     brouard  2437:     for(i=1,jk=1; i <=nlstate; i++){
                   2438:       for(k=1; k <=(nlstate+ndeath); k++){
                   2439:        if (k != i) {
                   2440:          printf("%d%d ",i,k);
                   2441:          fprintf(ficlog,"%d%d ",i,k);
                   2442:          for(j=1; j <=ncovmodel; j++){
                   2443:            printf("%12.7f ",p[jk]);
                   2444:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2445:            jk++; 
                   2446:          }
                   2447:          printf("\n");
                   2448:          fprintf(ficlog,"\n");
                   2449:        }
                   2450:       }
                   2451:     }
1.241     brouard  2452:     if(*iter <=3 && *iter >1){
1.157     brouard  2453:       tml = *localtime(&rcurr_time);
                   2454:       strcpy(strcurr,asctime(&tml));
                   2455:       rforecast_time=rcurr_time; 
1.126     brouard  2456:       itmp = strlen(strcurr);
                   2457:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2458:        strcurr[itmp-1]='\0';
1.162     brouard  2459:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2460:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2461:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2462:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2463:        forecast_time = *localtime(&rforecast_time);
                   2464:        strcpy(strfor,asctime(&forecast_time));
                   2465:        itmp = strlen(strfor);
                   2466:        if(strfor[itmp-1]=='\n')
                   2467:          strfor[itmp-1]='\0';
                   2468:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2469:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2470:       }
                   2471:     }
1.187     brouard  2472:     for (i=1;i<=n;i++) { /* For each direction i */
                   2473:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2474:       fptt=(*fret); 
                   2475: #ifdef DEBUG
1.203     brouard  2476:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2477:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2478: #endif
1.203     brouard  2479:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2480:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2481: #ifdef LINMINORIGINAL
1.188     brouard  2482:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2483: #else
                   2484:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2485:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2486: #endif
                   2487:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2488:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2489:                                /* because that direction will be replaced unless the gain del is small */
                   2490:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2491:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2492:                                /* with the new direction. */
                   2493:                                del=fabs(fptt-(*fret)); 
                   2494:                                ibig=i; 
1.126     brouard  2495:       } 
                   2496: #ifdef DEBUG
                   2497:       printf("%d %.12e",i,(*fret));
                   2498:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2499:       for (j=1;j<=n;j++) {
1.224     brouard  2500:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2501:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2502:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2503:       }
                   2504:       for(j=1;j<=n;j++) {
1.225     brouard  2505:                                printf(" p(%d)=%.12e",j,p[j]);
                   2506:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2507:       }
                   2508:       printf("\n");
                   2509:       fprintf(ficlog,"\n");
                   2510: #endif
1.187     brouard  2511:     } /* end loop on each direction i */
                   2512:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2513:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2514:     /* New value of last point Pn is not computed, P(n-1) */
1.319   ! brouard  2515:     for(j=1;j<=n;j++) {
        !          2516:       if(flatdir[j] >0){
        !          2517:         printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
        !          2518:         fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
1.302     brouard  2519:       }
1.319   ! brouard  2520:       /* printf("\n"); */
        !          2521:       /* fprintf(ficlog,"\n"); */
        !          2522:     }
1.243     brouard  2523:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2524:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2525:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2526:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2527:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2528:       /* decreased of more than 3.84  */
                   2529:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2530:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2531:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2532:                        
1.188     brouard  2533:       /* Starting the program with initial values given by a former maximization will simply change */
                   2534:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2535:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2536:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2537: #ifdef DEBUG
                   2538:       int k[2],l;
                   2539:       k[0]=1;
                   2540:       k[1]=-1;
                   2541:       printf("Max: %.12e",(*func)(p));
                   2542:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2543:       for (j=1;j<=n;j++) {
                   2544:        printf(" %.12e",p[j]);
                   2545:        fprintf(ficlog," %.12e",p[j]);
                   2546:       }
                   2547:       printf("\n");
                   2548:       fprintf(ficlog,"\n");
                   2549:       for(l=0;l<=1;l++) {
                   2550:        for (j=1;j<=n;j++) {
                   2551:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2552:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2553:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2554:        }
                   2555:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2556:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2557:       }
                   2558: #endif
                   2559: 
                   2560:       free_vector(xit,1,n); 
                   2561:       free_vector(xits,1,n); 
                   2562:       free_vector(ptt,1,n); 
                   2563:       free_vector(pt,1,n); 
                   2564:       return; 
1.192     brouard  2565:     } /* enough precision */ 
1.240     brouard  2566:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2567:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2568:       ptt[j]=2.0*p[j]-pt[j]; 
                   2569:       xit[j]=p[j]-pt[j]; 
                   2570:       pt[j]=p[j]; 
                   2571:     } 
1.181     brouard  2572:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2573: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2574:                if (*iter <=4) {
1.225     brouard  2575: #else
                   2576: #endif
1.224     brouard  2577: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2578: #else
1.161     brouard  2579:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2580: #endif
1.162     brouard  2581:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2582:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2583:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2584:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2585:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2586:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2587:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2588:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2589:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2590:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2591:       /* mu² and del² are equal when f3=f1 */
                   2592:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2593:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2594:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2595:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2596: #ifdef NRCORIGINAL
                   2597:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2598: #else
                   2599:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2600:       t= t- del*SQR(fp-fptt);
1.183     brouard  2601: #endif
1.202     brouard  2602:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2603: #ifdef DEBUG
1.181     brouard  2604:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2605:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2606:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2607:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2608:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2609:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2610:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2611:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2612: #endif
1.183     brouard  2613: #ifdef POWELLORIGINAL
                   2614:       if (t < 0.0) { /* Then we use it for new direction */
                   2615: #else
1.182     brouard  2616:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2617:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2618:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2619:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2620:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2621:       } 
1.181     brouard  2622:       if (directest < 0.0) { /* Then we use it for new direction */
                   2623: #endif
1.191     brouard  2624: #ifdef DEBUGLINMIN
1.234     brouard  2625:        printf("Before linmin in direction P%d-P0\n",n);
                   2626:        for (j=1;j<=n;j++) {
                   2627:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2628:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2629:          if(j % ncovmodel == 0){
                   2630:            printf("\n");
                   2631:            fprintf(ficlog,"\n");
                   2632:          }
                   2633:        }
1.224     brouard  2634: #endif
                   2635: #ifdef LINMINORIGINAL
1.234     brouard  2636:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2637: #else
1.234     brouard  2638:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2639:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2640: #endif
1.234     brouard  2641:        
1.191     brouard  2642: #ifdef DEBUGLINMIN
1.234     brouard  2643:        for (j=1;j<=n;j++) { 
                   2644:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2645:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2646:          if(j % ncovmodel == 0){
                   2647:            printf("\n");
                   2648:            fprintf(ficlog,"\n");
                   2649:          }
                   2650:        }
1.224     brouard  2651: #endif
1.234     brouard  2652:        for (j=1;j<=n;j++) { 
                   2653:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2654:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2655:        }
1.224     brouard  2656: #ifdef LINMINORIGINAL
                   2657: #else
1.234     brouard  2658:        for (j=1, flatd=0;j<=n;j++) {
                   2659:          if(flatdir[j]>0)
                   2660:            flatd++;
                   2661:        }
                   2662:        if(flatd >0){
1.255     brouard  2663:          printf("%d flat directions: ",flatd);
                   2664:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2665:          for (j=1;j<=n;j++) { 
                   2666:            if(flatdir[j]>0){
                   2667:              printf("%d ",j);
                   2668:              fprintf(ficlog,"%d ",j);
                   2669:            }
                   2670:          }
                   2671:          printf("\n");
                   2672:          fprintf(ficlog,"\n");
1.319   ! brouard  2673: #ifdef FLATSUP
        !          2674:           free_vector(xit,1,n); 
        !          2675:           free_vector(xits,1,n); 
        !          2676:           free_vector(ptt,1,n); 
        !          2677:           free_vector(pt,1,n); 
        !          2678:           return;
        !          2679: #endif
1.234     brouard  2680:        }
1.191     brouard  2681: #endif
1.234     brouard  2682:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2683:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2684:        
1.126     brouard  2685: #ifdef DEBUG
1.234     brouard  2686:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2687:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2688:        for(j=1;j<=n;j++){
                   2689:          printf(" %lf",xit[j]);
                   2690:          fprintf(ficlog," %lf",xit[j]);
                   2691:        }
                   2692:        printf("\n");
                   2693:        fprintf(ficlog,"\n");
1.126     brouard  2694: #endif
1.192     brouard  2695:       } /* end of t or directest negative */
1.224     brouard  2696: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2697: #else
1.234     brouard  2698:       } /* end if (fptt < fp)  */
1.192     brouard  2699: #endif
1.225     brouard  2700: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2701:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2702: #else
1.224     brouard  2703: #endif
1.234     brouard  2704:                } /* loop iteration */ 
1.126     brouard  2705: } 
1.234     brouard  2706:   
1.126     brouard  2707: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2708:   
1.235     brouard  2709:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2710:   {
1.279     brouard  2711:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2712:      *   (and selected quantitative values in nres)
                   2713:      *  by left multiplying the unit
                   2714:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2715:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2716:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2717:      * or prevalence in state 1, prevalence in state 2, 0
                   2718:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2719:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2720:      * Output is prlim.
                   2721:      * Initial matrix pimij 
                   2722:      */
1.206     brouard  2723:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2724:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2725:   /*  0,                   0                  , 1} */
                   2726:   /*
                   2727:    * and after some iteration: */
                   2728:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2729:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2730:   /*  0,                   0                  , 1} */
                   2731:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2732:   /* {0.51571254859325999, 0.4842874514067399, */
                   2733:   /*  0.51326036147820708, 0.48673963852179264} */
                   2734:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2735:     
1.126     brouard  2736:   int i, ii,j,k;
1.209     brouard  2737:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2738:   /* double **matprod2(); */ /* test */
1.218     brouard  2739:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2740:   double **newm;
1.209     brouard  2741:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2742:   int ncvloop=0;
1.288     brouard  2743:   int first=0;
1.169     brouard  2744:   
1.209     brouard  2745:   min=vector(1,nlstate);
                   2746:   max=vector(1,nlstate);
                   2747:   meandiff=vector(1,nlstate);
                   2748: 
1.218     brouard  2749:        /* Starting with matrix unity */
1.126     brouard  2750:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2751:     for (j=1;j<=nlstate+ndeath;j++){
                   2752:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2753:     }
1.169     brouard  2754:   
                   2755:   cov[1]=1.;
                   2756:   
                   2757:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2758:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2759:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2760:     ncvloop++;
1.126     brouard  2761:     newm=savm;
                   2762:     /* Covariates have to be included here again */
1.138     brouard  2763:     cov[2]=agefin;
1.319   ! brouard  2764:      if(nagesqr==1){
        !          2765:       cov[3]= agefin*agefin;
        !          2766:      }
1.234     brouard  2767:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2768:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2769:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.319   ! brouard  2770:       /* cov[++k1]=nbcode[TvarsD[k]][codtabm(ij,k)]; */
1.235     brouard  2771:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2772:     }
                   2773:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2774:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.319   ! brouard  2775:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k];
        !          2776:       /* cov[++k1]=Tqresult[nres][k];  */
1.235     brouard  2777:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2778:     }
1.237     brouard  2779:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.319   ! brouard  2780:       if(Dummy[Tage[k]]==2){ /* dummy with age */
1.234     brouard  2781:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319   ! brouard  2782:        /* cov[++k1]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
        !          2783:       } else if(Dummy[Tage[k]]==3){ /* quantitative with age */
        !          2784:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k];
        !          2785:        /* cov[++k1]=Tqresult[nres][k];  */
1.234     brouard  2786:       }
1.235     brouard  2787:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2788:     }
1.237     brouard  2789:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2790:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2791:       if(Dummy[Tvard[k][1]==0]){
                   2792:        if(Dummy[Tvard[k][2]==0]){
                   2793:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
1.319   ! brouard  2794:          /* cov[++k1]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.237     brouard  2795:        }else{
                   2796:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
1.319   ! brouard  2797:          /* cov[++k1]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k]; */
1.237     brouard  2798:        }
                   2799:       }else{
                   2800:        if(Dummy[Tvard[k][2]==0]){
                   2801:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
1.319   ! brouard  2802:          /* cov[++k1]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]]; */
1.237     brouard  2803:        }else{
                   2804:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
1.319   ! brouard  2805:          /* cov[++k1]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]]; */
1.237     brouard  2806:        }
                   2807:       }
1.234     brouard  2808:     }
1.138     brouard  2809:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2810:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2811:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2812:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2813:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.319   ! brouard  2814:     /* age and covariate values of ij are in 'cov' */
1.142     brouard  2815:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2816:     
1.126     brouard  2817:     savm=oldm;
                   2818:     oldm=newm;
1.209     brouard  2819: 
                   2820:     for(j=1; j<=nlstate; j++){
                   2821:       max[j]=0.;
                   2822:       min[j]=1.;
                   2823:     }
                   2824:     for(i=1;i<=nlstate;i++){
                   2825:       sumnew=0;
                   2826:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2827:       for(j=1; j<=nlstate; j++){ 
                   2828:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2829:        max[j]=FMAX(max[j],prlim[i][j]);
                   2830:        min[j]=FMIN(min[j],prlim[i][j]);
                   2831:       }
                   2832:     }
                   2833: 
1.126     brouard  2834:     maxmax=0.;
1.209     brouard  2835:     for(j=1; j<=nlstate; j++){
                   2836:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2837:       maxmax=FMAX(maxmax,meandiff[j]);
                   2838:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2839:     } /* j loop */
1.203     brouard  2840:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2841:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2842:     if(maxmax < ftolpl){
1.209     brouard  2843:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2844:       free_vector(min,1,nlstate);
                   2845:       free_vector(max,1,nlstate);
                   2846:       free_vector(meandiff,1,nlstate);
1.126     brouard  2847:       return prlim;
                   2848:     }
1.288     brouard  2849:   } /* agefin loop */
1.208     brouard  2850:     /* After some age loop it doesn't converge */
1.288     brouard  2851:   if(!first){
                   2852:     first=1;
                   2853:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
1.317     brouard  2854:     fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2855:   }else if (first >=1 && first <10){
                   2856:     fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2857:     first++;
                   2858:   }else if (first ==10){
                   2859:     fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2860:     printf("Warning: the stable prevalence dit not converge. This warning came too often, IMaCh will stop notifying, even in its log file. Look at the graphs to appreciate the non convergence.\n");
                   2861:     fprintf(ficlog,"Warning: the stable prevalence no convergence; too many cases, giving up noticing, even in log file\n");
                   2862:     first++;
1.288     brouard  2863:   }
                   2864: 
1.209     brouard  2865:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2866:   free_vector(min,1,nlstate);
                   2867:   free_vector(max,1,nlstate);
                   2868:   free_vector(meandiff,1,nlstate);
1.208     brouard  2869:   
1.169     brouard  2870:   return prlim; /* should not reach here */
1.126     brouard  2871: }
                   2872: 
1.217     brouard  2873: 
                   2874:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2875: 
1.218     brouard  2876:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2877:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2878:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2879: {
1.264     brouard  2880:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2881:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2882:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2883:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2884:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2885:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2886:   /* Initial matrix pimij */
                   2887:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2888:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2889:   /*  0,                   0                  , 1} */
                   2890:   /*
                   2891:    * and after some iteration: */
                   2892:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2893:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2894:   /*  0,                   0                  , 1} */
                   2895:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2896:   /* {0.51571254859325999, 0.4842874514067399, */
                   2897:   /*  0.51326036147820708, 0.48673963852179264} */
                   2898:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2899: 
                   2900:   int i, ii,j,k;
1.247     brouard  2901:   int first=0;
1.217     brouard  2902:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2903:   /* double **matprod2(); */ /* test */
                   2904:   double **out, cov[NCOVMAX+1], **bmij();
                   2905:   double **newm;
1.218     brouard  2906:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2907:   double        **oldm, **savm;  /* for use */
                   2908: 
1.217     brouard  2909:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2910:   int ncvloop=0;
                   2911:   
                   2912:   min=vector(1,nlstate);
                   2913:   max=vector(1,nlstate);
                   2914:   meandiff=vector(1,nlstate);
                   2915: 
1.266     brouard  2916:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2917:   oldm=oldms; savm=savms;
                   2918:   
                   2919:   /* Starting with matrix unity */
                   2920:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2921:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2922:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2923:     }
                   2924:   
                   2925:   cov[1]=1.;
                   2926:   
                   2927:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2928:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2929:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2930:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2931:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2932:     ncvloop++;
1.218     brouard  2933:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2934:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2935:     /* Covariates have to be included here again */
                   2936:     cov[2]=agefin;
1.319   ! brouard  2937:     if(nagesqr==1){
1.217     brouard  2938:       cov[3]= agefin*agefin;;
1.319   ! brouard  2939:     }
1.242     brouard  2940:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2941:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2942:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2943:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2944:     }
                   2945:     /* for (k=1; k<=cptcovn;k++) { */
                   2946:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2947:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2948:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2949:     /* } */
                   2950:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2951:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2952:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2953:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2954:     }
                   2955:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2956:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2957:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2958:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2959:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.319   ! brouard  2960:       /* if(Dummy[Tvar[Tage[k]]]== 2){ /\* dummy with age *\/ ERROR ???*/
        !          2961:       if(Dummy[Tage[k]]== 2){ /* dummy with age */
1.242     brouard  2962:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319   ! brouard  2963:       } else if(Dummy[Tage[k]]== 3){ /* quantitative with age */
        !          2964:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k];
1.242     brouard  2965:       }
                   2966:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2967:     }
                   2968:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2969:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2970:       if(Dummy[Tvard[k][1]==0]){
                   2971:        if(Dummy[Tvard[k][2]==0]){
                   2972:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2973:        }else{
                   2974:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2975:        }
                   2976:       }else{
                   2977:        if(Dummy[Tvard[k][2]==0]){
                   2978:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2979:        }else{
                   2980:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2981:        }
                   2982:       }
1.217     brouard  2983:     }
                   2984:     
                   2985:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2986:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2987:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2988:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2989:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2990:                /* ij should be linked to the correct index of cov */
                   2991:                /* age and covariate values ij are in 'cov', but we need to pass
                   2992:                 * ij for the observed prevalence at age and status and covariate
                   2993:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2994:                 */
                   2995:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2996:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2997:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2998:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2999:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   3000:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   3001:     /*         printf("%d newm= ",i); */
                   3002:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3003:     /*           printf("%f ",newm[i][j]); */
                   3004:     /*         } */
                   3005:     /*         printf("oldm * "); */
                   3006:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3007:     /*           printf("%f ",oldm[i][j]); */
                   3008:     /*         } */
1.268     brouard  3009:     /*         printf(" bmmij "); */
1.266     brouard  3010:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3011:     /*           printf("%f ",pmmij[i][j]); */
                   3012:     /*         } */
                   3013:     /*         printf("\n"); */
                   3014:     /*   } */
                   3015:     /* } */
1.217     brouard  3016:     savm=oldm;
                   3017:     oldm=newm;
1.266     brouard  3018: 
1.217     brouard  3019:     for(j=1; j<=nlstate; j++){
                   3020:       max[j]=0.;
                   3021:       min[j]=1.;
                   3022:     }
                   3023:     for(j=1; j<=nlstate; j++){ 
                   3024:       for(i=1;i<=nlstate;i++){
1.234     brouard  3025:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   3026:        bprlim[i][j]= newm[i][j];
                   3027:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   3028:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  3029:       }
                   3030:     }
1.218     brouard  3031:                
1.217     brouard  3032:     maxmax=0.;
                   3033:     for(i=1; i<=nlstate; i++){
1.318     brouard  3034:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column, could be nan! */
1.217     brouard  3035:       maxmax=FMAX(maxmax,meandiff[i]);
                   3036:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  3037:     } /* i loop */
1.217     brouard  3038:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  3039:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  3040:     if(maxmax < ftolpl){
1.220     brouard  3041:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  3042:       free_vector(min,1,nlstate);
                   3043:       free_vector(max,1,nlstate);
                   3044:       free_vector(meandiff,1,nlstate);
                   3045:       return bprlim;
                   3046:     }
1.288     brouard  3047:   } /* agefin loop */
1.217     brouard  3048:     /* After some age loop it doesn't converge */
1.288     brouard  3049:   if(!first){
1.247     brouard  3050:     first=1;
                   3051:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   3052: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   3053:   }
                   3054:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  3055: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   3056:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   3057:   free_vector(min,1,nlstate);
                   3058:   free_vector(max,1,nlstate);
                   3059:   free_vector(meandiff,1,nlstate);
                   3060:   
                   3061:   return bprlim; /* should not reach here */
                   3062: }
                   3063: 
1.126     brouard  3064: /*************** transition probabilities ***************/ 
                   3065: 
                   3066: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   3067: {
1.138     brouard  3068:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  3069:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  3070:      model to the ncovmodel covariates (including constant and age).
                   3071:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3072:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3073:      ncth covariate in the global vector x is given by the formula:
                   3074:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3075:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3076:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3077:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  3078:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  3079:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  3080:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  3081:   */
                   3082:   double s1, lnpijopii;
1.126     brouard  3083:   /*double t34;*/
1.164     brouard  3084:   int i,j, nc, ii, jj;
1.126     brouard  3085: 
1.223     brouard  3086:   for(i=1; i<= nlstate; i++){
                   3087:     for(j=1; j<i;j++){
                   3088:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3089:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3090:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3091:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3092:       }
                   3093:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3094:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3095:     }
                   3096:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3097:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3098:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3099:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3100:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3101:       }
                   3102:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3103:     }
                   3104:   }
1.218     brouard  3105:   
1.223     brouard  3106:   for(i=1; i<= nlstate; i++){
                   3107:     s1=0;
                   3108:     for(j=1; j<i; j++){
                   3109:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3110:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3111:     }
                   3112:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3113:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3114:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3115:     }
                   3116:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3117:     ps[i][i]=1./(s1+1.);
                   3118:     /* Computing other pijs */
                   3119:     for(j=1; j<i; j++)
                   3120:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3121:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3122:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3123:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3124:   } /* end i */
1.218     brouard  3125:   
1.223     brouard  3126:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3127:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3128:       ps[ii][jj]=0;
                   3129:       ps[ii][ii]=1;
                   3130:     }
                   3131:   }
1.294     brouard  3132: 
                   3133: 
1.223     brouard  3134:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3135:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3136:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3137:   /*   } */
                   3138:   /*   printf("\n "); */
                   3139:   /* } */
                   3140:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3141:   /*
                   3142:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  3143:                goto end;*/
1.266     brouard  3144:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  3145: }
                   3146: 
1.218     brouard  3147: /*************** backward transition probabilities ***************/ 
                   3148: 
                   3149:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3150: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3151:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   3152: {
1.302     brouard  3153:   /* Computes the backward probability at age agefin, cov[2], and covariate combination 'ij'. In fact cov is already filled and x too.
1.266     brouard  3154:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  3155:    */
1.218     brouard  3156:   int i, ii, j,k;
1.222     brouard  3157:   
                   3158:   double **out, **pmij();
                   3159:   double sumnew=0.;
1.218     brouard  3160:   double agefin;
1.292     brouard  3161:   double k3=0.; /* constant of the w_x diagonal matrix (in order for B to sum to 1 even for death state) */
1.222     brouard  3162:   double **dnewm, **dsavm, **doldm;
                   3163:   double **bbmij;
                   3164:   
1.218     brouard  3165:   doldm=ddoldms; /* global pointers */
1.222     brouard  3166:   dnewm=ddnewms;
                   3167:   dsavm=ddsavms;
1.318     brouard  3168: 
                   3169:   /* Debug */
                   3170:   /* printf("Bmij ij=%d, cov[2}=%f\n", ij, cov[2]); */
1.222     brouard  3171:   agefin=cov[2];
1.268     brouard  3172:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3173:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3174:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3175:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3176: 
                   3177:   /* P_x */
1.266     brouard  3178:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  3179:   /* outputs pmmij which is a stochastic matrix in row */
                   3180: 
                   3181:   /* Diag(w_x) */
1.292     brouard  3182:   /* Rescaling the cross-sectional prevalence: Problem with prevacurrent which can be zero */
1.268     brouard  3183:   sumnew=0.;
1.269     brouard  3184:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3185:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.297     brouard  3186:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]); */
1.268     brouard  3187:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3188:   }
                   3189:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3190:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3191:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3192:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3193:     }
                   3194:   }else{
                   3195:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3196:       for (j=1;j<=nlstate+ndeath;j++)
                   3197:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3198:     }
                   3199:     /* if(sumnew <0.9){ */
                   3200:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3201:     /* } */
                   3202:   }
                   3203:   k3=0.0;  /* We put the last diagonal to 0 */
                   3204:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3205:       doldm[ii][ii]= k3;
                   3206:   }
                   3207:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3208:   
1.292     brouard  3209:   /* Left product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm): diag[(w_i)*Px */
                   3210:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* was a Bug Valgrind */
1.268     brouard  3211: 
1.292     brouard  3212:   /* Diag(Sum_i w^i_x p^ij_x, should be the prevalence at age x+stepm */
1.268     brouard  3213:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3214:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3215:     sumnew=0.;
1.222     brouard  3216:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3217:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3218:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3219:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3220:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3221:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3222:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3223:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3224:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3225:        /* }else */
1.268     brouard  3226:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3227:     } /*End ii */
                   3228:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3229: 
1.292     brouard  3230:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* was a Bug Valgrind */
1.268     brouard  3231:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3232:   /* end bmij */
1.266     brouard  3233:   return ps; /*pointer is unchanged */
1.218     brouard  3234: }
1.217     brouard  3235: /*************** transition probabilities ***************/ 
                   3236: 
1.218     brouard  3237: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3238: {
                   3239:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3240:      computes the probability to be observed in state j being in state i by appying the
                   3241:      model to the ncovmodel covariates (including constant and age).
                   3242:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3243:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3244:      ncth covariate in the global vector x is given by the formula:
                   3245:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3246:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3247:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3248:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3249:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3250:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3251:   */
                   3252:   double s1, lnpijopii;
                   3253:   /*double t34;*/
                   3254:   int i,j, nc, ii, jj;
                   3255: 
1.234     brouard  3256:   for(i=1; i<= nlstate; i++){
                   3257:     for(j=1; j<i;j++){
                   3258:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3259:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3260:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3261:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3262:       }
                   3263:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3264:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3265:     }
                   3266:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3267:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3268:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3269:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3270:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3271:       }
                   3272:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3273:     }
                   3274:   }
                   3275:   
                   3276:   for(i=1; i<= nlstate; i++){
                   3277:     s1=0;
                   3278:     for(j=1; j<i; j++){
                   3279:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3280:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3281:     }
                   3282:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3283:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3284:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3285:     }
                   3286:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3287:     ps[i][i]=1./(s1+1.);
                   3288:     /* Computing other pijs */
                   3289:     for(j=1; j<i; j++)
                   3290:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3291:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3292:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3293:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3294:   } /* end i */
                   3295:   
                   3296:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3297:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3298:       ps[ii][jj]=0;
                   3299:       ps[ii][ii]=1;
                   3300:     }
                   3301:   }
1.296     brouard  3302:   /* Added for prevbcast */ /* Transposed matrix too */
1.234     brouard  3303:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3304:     s1=0.;
                   3305:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3306:       s1+=ps[ii][jj];
                   3307:     }
                   3308:     for(ii=1; ii<= nlstate; ii++){
                   3309:       ps[ii][jj]=ps[ii][jj]/s1;
                   3310:     }
                   3311:   }
                   3312:   /* Transposition */
                   3313:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3314:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3315:       s1=ps[ii][jj];
                   3316:       ps[ii][jj]=ps[jj][ii];
                   3317:       ps[jj][ii]=s1;
                   3318:     }
                   3319:   }
                   3320:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3321:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3322:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3323:   /*   } */
                   3324:   /*   printf("\n "); */
                   3325:   /* } */
                   3326:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3327:   /*
                   3328:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3329:     goto end;*/
                   3330:   return ps;
1.217     brouard  3331: }
                   3332: 
                   3333: 
1.126     brouard  3334: /**************** Product of 2 matrices ******************/
                   3335: 
1.145     brouard  3336: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3337: {
                   3338:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3339:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3340:   /* in, b, out are matrice of pointers which should have been initialized 
                   3341:      before: only the contents of out is modified. The function returns
                   3342:      a pointer to pointers identical to out */
1.145     brouard  3343:   int i, j, k;
1.126     brouard  3344:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3345:     for(k=ncolol; k<=ncoloh; k++){
                   3346:       out[i][k]=0.;
                   3347:       for(j=ncl; j<=nch; j++)
                   3348:        out[i][k] +=in[i][j]*b[j][k];
                   3349:     }
1.126     brouard  3350:   return out;
                   3351: }
                   3352: 
                   3353: 
                   3354: /************* Higher Matrix Product ***************/
                   3355: 
1.235     brouard  3356: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3357: {
1.218     brouard  3358:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3359:      'nhstepm*hstepm*stepm' months (i.e. until
                   3360:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3361:      nhstepm*hstepm matrices. 
                   3362:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3363:      (typically every 2 years instead of every month which is too big 
                   3364:      for the memory).
                   3365:      Model is determined by parameters x and covariates have to be 
                   3366:      included manually here. 
                   3367: 
                   3368:      */
                   3369: 
                   3370:   int i, j, d, h, k;
1.131     brouard  3371:   double **out, cov[NCOVMAX+1];
1.126     brouard  3372:   double **newm;
1.187     brouard  3373:   double agexact;
1.214     brouard  3374:   double agebegin, ageend;
1.126     brouard  3375: 
                   3376:   /* Hstepm could be zero and should return the unit matrix */
                   3377:   for (i=1;i<=nlstate+ndeath;i++)
                   3378:     for (j=1;j<=nlstate+ndeath;j++){
                   3379:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3380:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3381:     }
                   3382:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3383:   for(h=1; h <=nhstepm; h++){
                   3384:     for(d=1; d <=hstepm; d++){
                   3385:       newm=savm;
                   3386:       /* Covariates have to be included here again */
                   3387:       cov[1]=1.;
1.214     brouard  3388:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3389:       cov[2]=agexact;
1.319   ! brouard  3390:       if(nagesqr==1){
1.227     brouard  3391:        cov[3]= agexact*agexact;
1.319   ! brouard  3392:       }
1.235     brouard  3393:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
1.319   ! brouard  3394: /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
        !          3395:        /* codtabm(ij,k)  (1 & (ij-1) >> (k-1))+1 */
        !          3396: /*             V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
        !          3397: /*    k        1  2   3   4     5    6    7     8    9 */
        !          3398: /*Tvar[k]=     5  4   3   6     5    2    7     1    1 */
        !          3399: /*    nsd         1   2                              3 */ /* Counting single dummies covar fixed or tv */
        !          3400: /*TvarsD[nsd]     4   3                              1 */ /* ID of single dummy cova fixed or timevary*/
        !          3401: /*TvarsDind[k]    2   3                              9 */ /* position K of single dummy cova */
1.235     brouard  3402:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3403:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3404:       }
                   3405:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3406:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.319   ! brouard  3407:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k];
1.235     brouard  3408:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3409:       }
1.319   ! brouard  3410:       for (k=1; k<=cptcovage;k++){ /* For product with age V1+V1*age +V4 +age*V3 */
        !          3411:        /* 1+2 Tage[1]=2 TVar[2]=1 Dummy[2]=2, Tage[2]=4 TVar[4]=3 Dummy[4]=3 quant*/
        !          3412:        /* */
        !          3413:        if(Dummy[Tage[k]]== 2){ /* dummy with age */
        !          3414:        /* if(Dummy[Tvar[Tage[k]]]== 2){ /\* dummy with age *\/ */
1.235     brouard  3415:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319   ! brouard  3416:        } else if(Dummy[Tage[k]]== 3){ /* quantitative with age */
        !          3417:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k];
1.235     brouard  3418:        }
                   3419:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3420:       }
1.319   ! brouard  3421:       for (k=1; k<=cptcovprod;k++){ /*  For product without age */
1.235     brouard  3422:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.319   ! brouard  3423:        /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
        !          3424:        if(Dummy[Tvard[k][1]==0]){
        !          3425:          if(Dummy[Tvard[k][2]==0]){
        !          3426:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
        !          3427:          }else{
        !          3428:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
        !          3429:          }
        !          3430:        }else{
        !          3431:          if(Dummy[Tvard[k][2]==0]){
        !          3432:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
        !          3433:          }else{
        !          3434:            cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
        !          3435:          }
        !          3436:        }
1.235     brouard  3437:       }
                   3438:       /* for (k=1; k<=cptcovn;k++)  */
                   3439:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3440:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3441:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3442:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3443:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3444:       
                   3445:       
1.126     brouard  3446:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3447:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.319   ! brouard  3448:       /* right multiplication of oldm by the current matrix */
1.126     brouard  3449:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3450:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3451:       /* if((int)age == 70){ */
                   3452:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3453:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3454:       /*         printf("%d pmmij ",i); */
                   3455:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3456:       /*           printf("%f ",pmmij[i][j]); */
                   3457:       /*         } */
                   3458:       /*         printf(" oldm "); */
                   3459:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3460:       /*           printf("%f ",oldm[i][j]); */
                   3461:       /*         } */
                   3462:       /*         printf("\n"); */
                   3463:       /*       } */
                   3464:       /* } */
1.126     brouard  3465:       savm=oldm;
                   3466:       oldm=newm;
                   3467:     }
                   3468:     for(i=1; i<=nlstate+ndeath; i++)
                   3469:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3470:        po[i][j][h]=newm[i][j];
                   3471:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3472:       }
1.128     brouard  3473:     /*printf("h=%d ",h);*/
1.126     brouard  3474:   } /* end h */
1.267     brouard  3475:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3476:   return po;
                   3477: }
                   3478: 
1.217     brouard  3479: /************* Higher Back Matrix Product ***************/
1.218     brouard  3480: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3481: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3482: {
1.266     brouard  3483:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3484:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3485:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3486:      nhstepm*hstepm matrices.
                   3487:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3488:      (typically every 2 years instead of every month which is too big
1.217     brouard  3489:      for the memory).
1.218     brouard  3490:      Model is determined by parameters x and covariates have to be
1.266     brouard  3491:      included manually here. Then we use a call to bmij(x and cov)
                   3492:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3493:   */
1.217     brouard  3494: 
                   3495:   int i, j, d, h, k;
1.266     brouard  3496:   double **out, cov[NCOVMAX+1], **bmij();
                   3497:   double **newm, ***newmm;
1.217     brouard  3498:   double agexact;
                   3499:   double agebegin, ageend;
1.222     brouard  3500:   double **oldm, **savm;
1.217     brouard  3501: 
1.266     brouard  3502:   newmm=po; /* To be saved */
                   3503:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3504:   /* Hstepm could be zero and should return the unit matrix */
                   3505:   for (i=1;i<=nlstate+ndeath;i++)
                   3506:     for (j=1;j<=nlstate+ndeath;j++){
                   3507:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3508:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3509:     }
                   3510:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3511:   for(h=1; h <=nhstepm; h++){
                   3512:     for(d=1; d <=hstepm; d++){
                   3513:       newm=savm;
                   3514:       /* Covariates have to be included here again */
                   3515:       cov[1]=1.;
1.271     brouard  3516:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3517:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
1.318     brouard  3518:         /* Debug */
                   3519:       /* printf("hBxij age=%lf, agexact=%lf\n", age, agexact); */
1.217     brouard  3520:       cov[2]=agexact;
                   3521:       if(nagesqr==1)
1.222     brouard  3522:        cov[3]= agexact*agexact;
1.266     brouard  3523:       for (k=1; k<=cptcovn;k++){
                   3524:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3525:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3526:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3527:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3528:       }
1.267     brouard  3529:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3530:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3531:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3532:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3533:       }
1.319   ! brouard  3534:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 *//* For product with age */
        !          3535:        /* if(Dummy[Tvar[Tage[k]]]== 2){ /\* dummy with age error!!!*\/ */
        !          3536:        if(Dummy[Tage[k]]== 2){ /* dummy with age */
1.267     brouard  3537:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319   ! brouard  3538:        } else if(Dummy[Tage[k]]== 3){ /* quantitative with age */
1.267     brouard  3539:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3540:        }
                   3541:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3542:       }
                   3543:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3544:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3545:       }                        
1.217     brouard  3546:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3547:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3548: 
1.218     brouard  3549:       /* Careful transposed matrix */
1.266     brouard  3550:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3551:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3552:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3553:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3554:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3555:       /* if((int)age == 70){ */
                   3556:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3557:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3558:       /*         printf("%d pmmij ",i); */
                   3559:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3560:       /*           printf("%f ",pmmij[i][j]); */
                   3561:       /*         } */
                   3562:       /*         printf(" oldm "); */
                   3563:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3564:       /*           printf("%f ",oldm[i][j]); */
                   3565:       /*         } */
                   3566:       /*         printf("\n"); */
                   3567:       /*       } */
                   3568:       /* } */
                   3569:       savm=oldm;
                   3570:       oldm=newm;
                   3571:     }
                   3572:     for(i=1; i<=nlstate+ndeath; i++)
                   3573:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3574:        po[i][j][h]=newm[i][j];
1.268     brouard  3575:        /* if(h==nhstepm) */
                   3576:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3577:       }
1.268     brouard  3578:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3579:   } /* end h */
1.268     brouard  3580:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3581:   return po;
                   3582: }
                   3583: 
                   3584: 
1.162     brouard  3585: #ifdef NLOPT
                   3586:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3587:   double fret;
                   3588:   double *xt;
                   3589:   int j;
                   3590:   myfunc_data *d2 = (myfunc_data *) pd;
                   3591: /* xt = (p1-1); */
                   3592:   xt=vector(1,n); 
                   3593:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3594: 
                   3595:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3596:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3597:   printf("Function = %.12lf ",fret);
                   3598:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3599:   printf("\n");
                   3600:  free_vector(xt,1,n);
                   3601:   return fret;
                   3602: }
                   3603: #endif
1.126     brouard  3604: 
                   3605: /*************** log-likelihood *************/
                   3606: double func( double *x)
                   3607: {
1.226     brouard  3608:   int i, ii, j, k, mi, d, kk;
                   3609:   int ioffset=0;
                   3610:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3611:   double **out;
                   3612:   double lli; /* Individual log likelihood */
                   3613:   int s1, s2;
1.228     brouard  3614:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3615:   double bbh, survp;
                   3616:   long ipmx;
                   3617:   double agexact;
                   3618:   /*extern weight */
                   3619:   /* We are differentiating ll according to initial status */
                   3620:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3621:   /*for(i=1;i<imx;i++) 
                   3622:     printf(" %d\n",s[4][i]);
                   3623:   */
1.162     brouard  3624: 
1.226     brouard  3625:   ++countcallfunc;
1.162     brouard  3626: 
1.226     brouard  3627:   cov[1]=1.;
1.126     brouard  3628: 
1.226     brouard  3629:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3630:   ioffset=0;
1.226     brouard  3631:   if(mle==1){
                   3632:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3633:       /* Computes the values of the ncovmodel covariates of the model
                   3634:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3635:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3636:         to be observed in j being in i according to the model.
                   3637:       */
1.243     brouard  3638:       ioffset=2+nagesqr ;
1.233     brouard  3639:    /* Fixed */
1.319   ! brouard  3640:       for (k=1; k<=ncovf;k++){ /* For each fixed covariate dummu or quant or prod */
        !          3641:        /* # V1=sex, V2=raedyrs Quant Fixed, State=livarnb4..livarnb11, V3=iadl4..iald11, V4=adlw4..adlw11, V5=r4bmi..r11bmi */
        !          3642:         /*             V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
        !          3643:        /*  TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  ID of fixed covariates or product V2, V1*V2, V1 */
        !          3644:         /* TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, TvarFind[3]=9 *//* Inverse V2(6) is first fixed (single or prod)  */
        !          3645:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (TvarFind[1]=6)*/
        !          3646:        /* V1*V2 (7)  TvarFind[2]=7, TvarFind[3]=9 */
1.234     brouard  3647:       }
1.226     brouard  3648:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
1.319   ! brouard  3649:         is 5, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2]=6 
1.226     brouard  3650:         has been calculated etc */
                   3651:       /* For an individual i, wav[i] gives the number of effective waves */
                   3652:       /* We compute the contribution to Likelihood of each effective transition
                   3653:         mw[mi][i] is real wave of the mi th effectve wave */
                   3654:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3655:         s2=s[mw[mi+1][i]][i];
                   3656:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3657:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3658:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3659:       */
                   3660:       for(mi=1; mi<= wav[i]-1; mi++){
1.319   ! brouard  3661:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates in the model (single and product but no age )"V5+V4+V3+V4*V3+V5*age+V1*age+V1" +TvarVind 1,2,3,4(V4*V3)  Tvar[1]@7{5, 4, 3, 6, 5, 1, 1 ; 6 because the created covar is after V5 and is 6, minus 1+1, 3,2,1,4 positions in cotvar*/
        !          3662:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; but where is the crossproduct? */
1.242     brouard  3663:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3664:        }
                   3665:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3666:          for (j=1;j<=nlstate+ndeath;j++){
                   3667:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3668:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3669:          }
                   3670:        for(d=0; d<dh[mi][i]; d++){
                   3671:          newm=savm;
                   3672:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3673:          cov[2]=agexact;
                   3674:          if(nagesqr==1)
                   3675:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3676:          for (kk=1; kk<=cptcovage;kk++) {
1.318     brouard  3677:            if(!FixedV[Tvar[Tage[kk]]])
                   3678:              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
                   3679:            else
                   3680:              cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3681:          }
                   3682:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3683:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3684:          savm=oldm;
                   3685:          oldm=newm;
                   3686:        } /* end mult */
                   3687:        
                   3688:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3689:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3690:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3691:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3692:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3693:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3694:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3695:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3696:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3697:                                 * -stepm/2 to stepm/2 .
                   3698:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3699:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3700:                                 */
1.234     brouard  3701:        s1=s[mw[mi][i]][i];
                   3702:        s2=s[mw[mi+1][i]][i];
                   3703:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3704:        /* bias bh is positive if real duration
                   3705:         * is higher than the multiple of stepm and negative otherwise.
                   3706:         */
                   3707:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3708:        if( s2 > nlstate){ 
                   3709:          /* i.e. if s2 is a death state and if the date of death is known 
                   3710:             then the contribution to the likelihood is the probability to 
                   3711:             die between last step unit time and current  step unit time, 
                   3712:             which is also equal to probability to die before dh 
                   3713:             minus probability to die before dh-stepm . 
                   3714:             In version up to 0.92 likelihood was computed
                   3715:             as if date of death was unknown. Death was treated as any other
                   3716:             health state: the date of the interview describes the actual state
                   3717:             and not the date of a change in health state. The former idea was
                   3718:             to consider that at each interview the state was recorded
                   3719:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3720:             introduced the exact date of death then we should have modified
                   3721:             the contribution of an exact death to the likelihood. This new
                   3722:             contribution is smaller and very dependent of the step unit
                   3723:             stepm. It is no more the probability to die between last interview
                   3724:             and month of death but the probability to survive from last
                   3725:             interview up to one month before death multiplied by the
                   3726:             probability to die within a month. Thanks to Chris
                   3727:             Jackson for correcting this bug.  Former versions increased
                   3728:             mortality artificially. The bad side is that we add another loop
                   3729:             which slows down the processing. The difference can be up to 10%
                   3730:             lower mortality.
                   3731:          */
                   3732:          /* If, at the beginning of the maximization mostly, the
                   3733:             cumulative probability or probability to be dead is
                   3734:             constant (ie = 1) over time d, the difference is equal to
                   3735:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3736:             s1 at precedent wave, to be dead a month before current
                   3737:             wave is equal to probability, being at state s1 at
                   3738:             precedent wave, to be dead at mont of the current
                   3739:             wave. Then the observed probability (that this person died)
                   3740:             is null according to current estimated parameter. In fact,
                   3741:             it should be very low but not zero otherwise the log go to
                   3742:             infinity.
                   3743:          */
1.183     brouard  3744: /* #ifdef INFINITYORIGINAL */
                   3745: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3746: /* #else */
                   3747: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3748: /*         lli=log(mytinydouble); */
                   3749: /*       else */
                   3750: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3751: /* #endif */
1.226     brouard  3752:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3753:          
1.226     brouard  3754:        } else if  ( s2==-1 ) { /* alive */
                   3755:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3756:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3757:          /*survp += out[s1][j]; */
                   3758:          lli= log(survp);
                   3759:        }
                   3760:        else if  (s2==-4) { 
                   3761:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3762:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3763:          lli= log(survp); 
                   3764:        } 
                   3765:        else if  (s2==-5) { 
                   3766:          for (j=1,survp=0. ; j<=2; j++)  
                   3767:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3768:          lli= log(survp); 
                   3769:        } 
                   3770:        else{
                   3771:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3772:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3773:        } 
                   3774:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3775:        /*if(lli ==000.0)*/
                   3776:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3777:        ipmx +=1;
                   3778:        sw += weight[i];
                   3779:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3780:        /* if (lli < log(mytinydouble)){ */
                   3781:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3782:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3783:        /* } */
                   3784:       } /* end of wave */
                   3785:     } /* end of individual */
                   3786:   }  else if(mle==2){
                   3787:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.319   ! brouard  3788:       ioffset=2+nagesqr ;
        !          3789:       for (k=1; k<=ncovf;k++)
        !          3790:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];
1.226     brouard  3791:       for(mi=1; mi<= wav[i]-1; mi++){
1.319   ! brouard  3792:        for(k=1; k <= ncovv ; k++){
        !          3793:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
        !          3794:        }
1.226     brouard  3795:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3796:          for (j=1;j<=nlstate+ndeath;j++){
                   3797:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3798:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3799:          }
                   3800:        for(d=0; d<=dh[mi][i]; d++){
                   3801:          newm=savm;
                   3802:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3803:          cov[2]=agexact;
                   3804:          if(nagesqr==1)
                   3805:            cov[3]= agexact*agexact;
                   3806:          for (kk=1; kk<=cptcovage;kk++) {
                   3807:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3808:          }
                   3809:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3810:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3811:          savm=oldm;
                   3812:          oldm=newm;
                   3813:        } /* end mult */
                   3814:       
                   3815:        s1=s[mw[mi][i]][i];
                   3816:        s2=s[mw[mi+1][i]][i];
                   3817:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3818:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3819:        ipmx +=1;
                   3820:        sw += weight[i];
                   3821:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3822:       } /* end of wave */
                   3823:     } /* end of individual */
                   3824:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3825:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3826:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3827:       for(mi=1; mi<= wav[i]-1; mi++){
                   3828:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3829:          for (j=1;j<=nlstate+ndeath;j++){
                   3830:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3831:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3832:          }
                   3833:        for(d=0; d<dh[mi][i]; d++){
                   3834:          newm=savm;
                   3835:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3836:          cov[2]=agexact;
                   3837:          if(nagesqr==1)
                   3838:            cov[3]= agexact*agexact;
                   3839:          for (kk=1; kk<=cptcovage;kk++) {
                   3840:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3841:          }
                   3842:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3843:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3844:          savm=oldm;
                   3845:          oldm=newm;
                   3846:        } /* end mult */
                   3847:       
                   3848:        s1=s[mw[mi][i]][i];
                   3849:        s2=s[mw[mi+1][i]][i];
                   3850:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3851:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3852:        ipmx +=1;
                   3853:        sw += weight[i];
                   3854:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3855:       } /* end of wave */
                   3856:     } /* end of individual */
                   3857:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3858:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3859:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3860:       for(mi=1; mi<= wav[i]-1; mi++){
                   3861:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3862:          for (j=1;j<=nlstate+ndeath;j++){
                   3863:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3864:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3865:          }
                   3866:        for(d=0; d<dh[mi][i]; d++){
                   3867:          newm=savm;
                   3868:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3869:          cov[2]=agexact;
                   3870:          if(nagesqr==1)
                   3871:            cov[3]= agexact*agexact;
                   3872:          for (kk=1; kk<=cptcovage;kk++) {
                   3873:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3874:          }
1.126     brouard  3875:        
1.226     brouard  3876:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3877:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3878:          savm=oldm;
                   3879:          oldm=newm;
                   3880:        } /* end mult */
                   3881:       
                   3882:        s1=s[mw[mi][i]][i];
                   3883:        s2=s[mw[mi+1][i]][i];
                   3884:        if( s2 > nlstate){ 
                   3885:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3886:        } else if  ( s2==-1 ) { /* alive */
                   3887:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3888:            survp += out[s1][j];
                   3889:          lli= log(survp);
                   3890:        }else{
                   3891:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3892:        }
                   3893:        ipmx +=1;
                   3894:        sw += weight[i];
                   3895:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3896: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3897:       } /* end of wave */
                   3898:     } /* end of individual */
                   3899:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3900:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3901:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3902:       for(mi=1; mi<= wav[i]-1; mi++){
                   3903:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3904:          for (j=1;j<=nlstate+ndeath;j++){
                   3905:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3906:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3907:          }
                   3908:        for(d=0; d<dh[mi][i]; d++){
                   3909:          newm=savm;
                   3910:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3911:          cov[2]=agexact;
                   3912:          if(nagesqr==1)
                   3913:            cov[3]= agexact*agexact;
                   3914:          for (kk=1; kk<=cptcovage;kk++) {
                   3915:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3916:          }
1.126     brouard  3917:        
1.226     brouard  3918:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3919:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3920:          savm=oldm;
                   3921:          oldm=newm;
                   3922:        } /* end mult */
                   3923:       
                   3924:        s1=s[mw[mi][i]][i];
                   3925:        s2=s[mw[mi+1][i]][i];
                   3926:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3927:        ipmx +=1;
                   3928:        sw += weight[i];
                   3929:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3930:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3931:       } /* end of wave */
                   3932:     } /* end of individual */
                   3933:   } /* End of if */
                   3934:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3935:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3936:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3937:   return -l;
1.126     brouard  3938: }
                   3939: 
                   3940: /*************** log-likelihood *************/
                   3941: double funcone( double *x)
                   3942: {
1.228     brouard  3943:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3944:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3945:   int ioffset=0;
1.131     brouard  3946:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3947:   double **out;
                   3948:   double lli; /* Individual log likelihood */
                   3949:   double llt;
                   3950:   int s1, s2;
1.228     brouard  3951:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3952: 
1.126     brouard  3953:   double bbh, survp;
1.187     brouard  3954:   double agexact;
1.214     brouard  3955:   double agebegin, ageend;
1.126     brouard  3956:   /*extern weight */
                   3957:   /* We are differentiating ll according to initial status */
                   3958:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3959:   /*for(i=1;i<imx;i++) 
                   3960:     printf(" %d\n",s[4][i]);
                   3961:   */
                   3962:   cov[1]=1.;
                   3963: 
                   3964:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3965:   ioffset=0;
                   3966:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3967:     /* ioffset=2+nagesqr+cptcovage; */
                   3968:     ioffset=2+nagesqr;
1.232     brouard  3969:     /* Fixed */
1.224     brouard  3970:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3971:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
1.311     brouard  3972:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products *//* Missing values are set to -1 but should be dropped */
1.232     brouard  3973:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3974: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3975: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3976: /*    cov[2+6]=covar[2][i]; V2  */
                   3977: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3978: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3979: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3980: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3981: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3982: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3983:     }
1.232     brouard  3984:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3985:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3986:     /* } */
1.231     brouard  3987:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3988:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3989:     /* } */
1.225     brouard  3990:     
1.233     brouard  3991: 
                   3992:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3993:     /* Wave varying (but not age varying) */
                   3994:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3995:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3996:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3997:       }
1.232     brouard  3998:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3999:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   4000:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   4001:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   4002:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   4003:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  4004:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  4005:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   4006:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   4007:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  4008:       /* } */
1.126     brouard  4009:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  4010:        for (j=1;j<=nlstate+ndeath;j++){
                   4011:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   4012:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   4013:        }
1.214     brouard  4014:       
                   4015:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   4016:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   4017:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  4018:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  4019:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4020:          and mw[mi+1][i]. dh depends on stepm.*/
                   4021:        newm=savm;
1.247     brouard  4022:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  4023:        cov[2]=agexact;
                   4024:        if(nagesqr==1)
                   4025:          cov[3]= agexact*agexact;
                   4026:        for (kk=1; kk<=cptcovage;kk++) {
                   4027:          if(!FixedV[Tvar[Tage[kk]]])
                   4028:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   4029:          else
                   4030:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   4031:        }
                   4032:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   4033:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   4034:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   4035:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   4036:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   4037:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   4038:        savm=oldm;
                   4039:        oldm=newm;
1.126     brouard  4040:       } /* end mult */
                   4041:       
                   4042:       s1=s[mw[mi][i]][i];
                   4043:       s2=s[mw[mi+1][i]][i];
1.217     brouard  4044:       /* if(s2==-1){ */
1.268     brouard  4045:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  4046:       /*       /\* exit(1); *\/ */
                   4047:       /* } */
1.126     brouard  4048:       bbh=(double)bh[mi][i]/(double)stepm; 
                   4049:       /* bias is positive if real duration
                   4050:        * is higher than the multiple of stepm and negative otherwise.
                   4051:        */
                   4052:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  4053:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  4054:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  4055:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   4056:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   4057:        lli= log(survp);
1.126     brouard  4058:       }else if (mle==1){
1.242     brouard  4059:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  4060:       } else if(mle==2){
1.242     brouard  4061:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  4062:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  4063:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  4064:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  4065:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  4066:       } else{  /* mle=0 back to 1 */
1.242     brouard  4067:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   4068:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  4069:       } /* End of if */
                   4070:       ipmx +=1;
                   4071:       sw += weight[i];
                   4072:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  4073:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  4074:       if(globpr){
1.246     brouard  4075:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  4076:  %11.6f %11.6f %11.6f ", \
1.242     brouard  4077:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  4078:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  4079:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   4080:          llt +=ll[k]*gipmx/gsw;
                   4081:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   4082:        }
                   4083:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  4084:       }
1.232     brouard  4085:        } /* end of wave */
                   4086: } /* end of individual */
                   4087: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   4088: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   4089: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   4090: if(globpr==0){ /* First time we count the contributions and weights */
                   4091:        gipmx=ipmx;
                   4092:        gsw=sw;
                   4093: }
                   4094: return -l;
1.126     brouard  4095: }
                   4096: 
                   4097: 
                   4098: /*************** function likelione ***********/
1.292     brouard  4099: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*func)(double []))
1.126     brouard  4100: {
                   4101:   /* This routine should help understanding what is done with 
                   4102:      the selection of individuals/waves and
                   4103:      to check the exact contribution to the likelihood.
                   4104:      Plotting could be done.
                   4105:    */
                   4106:   int k;
                   4107: 
                   4108:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  4109:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  4110:     strcat(fileresilk,fileresu);
1.126     brouard  4111:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   4112:       printf("Problem with resultfile: %s\n", fileresilk);
                   4113:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   4114:     }
1.214     brouard  4115:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   4116:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  4117:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   4118:     for(k=1; k<=nlstate; k++) 
                   4119:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   4120:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   4121:   }
                   4122: 
1.292     brouard  4123:   *fretone=(*func)(p);
1.126     brouard  4124:   if(*globpri !=0){
                   4125:     fclose(ficresilk);
1.205     brouard  4126:     if (mle ==0)
                   4127:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   4128:     else if(mle >=1)
                   4129:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   4130:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  4131:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  4132:       
                   4133:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  4134:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  4135: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   4136:     }
1.207     brouard  4137:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  4138: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4139:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  4140: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4141:     fflush(fichtm);
1.205     brouard  4142:   }
1.126     brouard  4143:   return;
                   4144: }
                   4145: 
                   4146: 
                   4147: /*********** Maximum Likelihood Estimation ***************/
                   4148: 
                   4149: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   4150: {
1.319   ! brouard  4151:   int i,j,k, jk, jkk=0, iter=0;
1.126     brouard  4152:   double **xi;
                   4153:   double fret;
                   4154:   double fretone; /* Only one call to likelihood */
                   4155:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  4156: 
                   4157: #ifdef NLOPT
                   4158:   int creturn;
                   4159:   nlopt_opt opt;
                   4160:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   4161:   double *lb;
                   4162:   double minf; /* the minimum objective value, upon return */
                   4163:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   4164:   myfunc_data dinst, *d = &dinst;
                   4165: #endif
                   4166: 
                   4167: 
1.126     brouard  4168:   xi=matrix(1,npar,1,npar);
                   4169:   for (i=1;i<=npar;i++)
                   4170:     for (j=1;j<=npar;j++)
                   4171:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   4172:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  4173:   strcpy(filerespow,"POW_"); 
1.126     brouard  4174:   strcat(filerespow,fileres);
                   4175:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   4176:     printf("Problem with resultfile: %s\n", filerespow);
                   4177:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   4178:   }
                   4179:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   4180:   for (i=1;i<=nlstate;i++)
                   4181:     for(j=1;j<=nlstate+ndeath;j++)
                   4182:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   4183:   fprintf(ficrespow,"\n");
1.162     brouard  4184: #ifdef POWELL
1.319   ! brouard  4185: #ifdef LINMINORIGINAL
        !          4186: #else /* LINMINORIGINAL */
        !          4187:   
        !          4188:   flatdir=ivector(1,npar); 
        !          4189:   for (j=1;j<=npar;j++) flatdir[j]=0; 
        !          4190: #endif /*LINMINORIGINAL */
        !          4191: 
        !          4192: #ifdef FLATSUP
        !          4193:   powell(p,xi,npar,ftol,&iter,&fret,flatdir,func);
        !          4194:   /* reorganizing p by suppressing flat directions */
        !          4195:   for(i=1, jk=1; i <=nlstate; i++){
        !          4196:     for(k=1; k <=(nlstate+ndeath); k++){
        !          4197:       if (k != i) {
        !          4198:         printf("%d%d flatdir[%d]=%d",i,k,jk, flatdir[jk]);
        !          4199:         if(flatdir[jk]==1){
        !          4200:           printf(" To be skipped %d%d flatdir[%d]=%d ",i,k,jk, flatdir[jk]);
        !          4201:         }
        !          4202:         for(j=1; j <=ncovmodel; j++){
        !          4203:           printf("%12.7f ",p[jk]);
        !          4204:           jk++; 
        !          4205:         }
        !          4206:         printf("\n");
        !          4207:       }
        !          4208:     }
        !          4209:   }
        !          4210: /* skipping */
        !          4211:   /* for(i=1, jk=1, jkk=1;(flatdir[jk]==0)&& (i <=nlstate); i++){ */
        !          4212:   for(i=1, jk=1, jkk=1;i <=nlstate; i++){
        !          4213:     for(k=1; k <=(nlstate+ndeath); k++){
        !          4214:       if (k != i) {
        !          4215:         printf("%d%d flatdir[%d]=%d",i,k,jk, flatdir[jk]);
        !          4216:         if(flatdir[jk]==1){
        !          4217:           printf(" To be skipped %d%d flatdir[%d]=%d jk=%d p[%d] ",i,k,jk, flatdir[jk],jk, jk);
        !          4218:           for(j=1; j <=ncovmodel;  jk++,j++){
        !          4219:             printf(" p[%d]=%12.7f",jk, p[jk]);
        !          4220:             /*q[jjk]=p[jk];*/
        !          4221:           }
        !          4222:         }else{
        !          4223:           printf(" To be kept %d%d flatdir[%d]=%d jk=%d q[%d]=p[%d] ",i,k,jk, flatdir[jk],jk, jkk, jk);
        !          4224:           for(j=1; j <=ncovmodel;  jk++,jkk++,j++){
        !          4225:             printf(" p[%d]=%12.7f=q[%d]",jk, p[jk],jkk);
        !          4226:             /*q[jjk]=p[jk];*/
        !          4227:           }
        !          4228:         }
        !          4229:         printf("\n");
        !          4230:       }
        !          4231:       fflush(stdout);
        !          4232:     }
        !          4233:   }
        !          4234:   powell(p,xi,npar,ftol,&iter,&fret,flatdir,func);
        !          4235: #else  /* FLATSUP */
1.126     brouard  4236:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.319   ! brouard  4237: #endif  /* FLATSUP */
        !          4238: 
        !          4239: #ifdef LINMINORIGINAL
        !          4240: #else
        !          4241:       free_ivector(flatdir,1,npar); 
        !          4242: #endif  /* LINMINORIGINAL*/
        !          4243: #endif /* POWELL */
1.126     brouard  4244: 
1.162     brouard  4245: #ifdef NLOPT
                   4246: #ifdef NEWUOA
                   4247:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   4248: #else
                   4249:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   4250: #endif
                   4251:   lb=vector(0,npar-1);
                   4252:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   4253:   nlopt_set_lower_bounds(opt, lb);
                   4254:   nlopt_set_initial_step1(opt, 0.1);
                   4255:   
                   4256:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   4257:   d->function = func;
                   4258:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   4259:   nlopt_set_min_objective(opt, myfunc, d);
                   4260:   nlopt_set_xtol_rel(opt, ftol);
                   4261:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   4262:     printf("nlopt failed! %d\n",creturn); 
                   4263:   }
                   4264:   else {
                   4265:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4266:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4267:     iter=1; /* not equal */
                   4268:   }
                   4269:   nlopt_destroy(opt);
                   4270: #endif
1.319   ! brouard  4271: #ifdef FLATSUP
        !          4272:   /* npared = npar -flatd/ncovmodel; */
        !          4273:   /* xired= matrix(1,npared,1,npared); */
        !          4274:   /* paramred= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */
        !          4275:   /* powell(pred,xired,npared,ftol,&iter,&fret,flatdir,func); */
        !          4276:   /* free_matrix(xire,1,npared,1,npared); */
        !          4277: #else  /* FLATSUP */
        !          4278: #endif /* FLATSUP */
1.126     brouard  4279:   free_matrix(xi,1,npar,1,npar);
                   4280:   fclose(ficrespow);
1.203     brouard  4281:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4282:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4283:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4284: 
                   4285: }
                   4286: 
                   4287: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4288: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4289: {
                   4290:   double  **a,**y,*x,pd;
1.203     brouard  4291:   /* double **hess; */
1.164     brouard  4292:   int i, j;
1.126     brouard  4293:   int *indx;
                   4294: 
                   4295:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4296:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4297:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4298:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4299:   double gompertz(double p[]);
1.203     brouard  4300:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4301: 
                   4302:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4303:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4304:   for (i=1;i<=npar;i++){
1.203     brouard  4305:     printf("%d-",i);fflush(stdout);
                   4306:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4307:    
                   4308:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4309:     
                   4310:     /*  printf(" %f ",p[i]);
                   4311:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4312:   }
                   4313:   
                   4314:   for (i=1;i<=npar;i++) {
                   4315:     for (j=1;j<=npar;j++)  {
                   4316:       if (j>i) { 
1.203     brouard  4317:        printf(".%d-%d",i,j);fflush(stdout);
                   4318:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4319:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4320:        
                   4321:        hess[j][i]=hess[i][j];    
                   4322:        /*printf(" %lf ",hess[i][j]);*/
                   4323:       }
                   4324:     }
                   4325:   }
                   4326:   printf("\n");
                   4327:   fprintf(ficlog,"\n");
                   4328: 
                   4329:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4330:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4331:   
                   4332:   a=matrix(1,npar,1,npar);
                   4333:   y=matrix(1,npar,1,npar);
                   4334:   x=vector(1,npar);
                   4335:   indx=ivector(1,npar);
                   4336:   for (i=1;i<=npar;i++)
                   4337:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4338:   ludcmp(a,npar,indx,&pd);
                   4339: 
                   4340:   for (j=1;j<=npar;j++) {
                   4341:     for (i=1;i<=npar;i++) x[i]=0;
                   4342:     x[j]=1;
                   4343:     lubksb(a,npar,indx,x);
                   4344:     for (i=1;i<=npar;i++){ 
                   4345:       matcov[i][j]=x[i];
                   4346:     }
                   4347:   }
                   4348: 
                   4349:   printf("\n#Hessian matrix#\n");
                   4350:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4351:   for (i=1;i<=npar;i++) { 
                   4352:     for (j=1;j<=npar;j++) { 
1.203     brouard  4353:       printf("%.6e ",hess[i][j]);
                   4354:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4355:     }
                   4356:     printf("\n");
                   4357:     fprintf(ficlog,"\n");
                   4358:   }
                   4359: 
1.203     brouard  4360:   /* printf("\n#Covariance matrix#\n"); */
                   4361:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4362:   /* for (i=1;i<=npar;i++) {  */
                   4363:   /*   for (j=1;j<=npar;j++) {  */
                   4364:   /*     printf("%.6e ",matcov[i][j]); */
                   4365:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4366:   /*   } */
                   4367:   /*   printf("\n"); */
                   4368:   /*   fprintf(ficlog,"\n"); */
                   4369:   /* } */
                   4370: 
1.126     brouard  4371:   /* Recompute Inverse */
1.203     brouard  4372:   /* for (i=1;i<=npar;i++) */
                   4373:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4374:   /* ludcmp(a,npar,indx,&pd); */
                   4375: 
                   4376:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4377: 
                   4378:   /* for (j=1;j<=npar;j++) { */
                   4379:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4380:   /*   x[j]=1; */
                   4381:   /*   lubksb(a,npar,indx,x); */
                   4382:   /*   for (i=1;i<=npar;i++){  */
                   4383:   /*     y[i][j]=x[i]; */
                   4384:   /*     printf("%.3e ",y[i][j]); */
                   4385:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4386:   /*   } */
                   4387:   /*   printf("\n"); */
                   4388:   /*   fprintf(ficlog,"\n"); */
                   4389:   /* } */
                   4390: 
                   4391:   /* Verifying the inverse matrix */
                   4392: #ifdef DEBUGHESS
                   4393:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4394: 
1.203     brouard  4395:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4396:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4397: 
                   4398:   for (j=1;j<=npar;j++) {
                   4399:     for (i=1;i<=npar;i++){ 
1.203     brouard  4400:       printf("%.2f ",y[i][j]);
                   4401:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4402:     }
                   4403:     printf("\n");
                   4404:     fprintf(ficlog,"\n");
                   4405:   }
1.203     brouard  4406: #endif
1.126     brouard  4407: 
                   4408:   free_matrix(a,1,npar,1,npar);
                   4409:   free_matrix(y,1,npar,1,npar);
                   4410:   free_vector(x,1,npar);
                   4411:   free_ivector(indx,1,npar);
1.203     brouard  4412:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4413: 
                   4414: 
                   4415: }
                   4416: 
                   4417: /*************** hessian matrix ****************/
                   4418: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4419: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4420:   int i;
                   4421:   int l=1, lmax=20;
1.203     brouard  4422:   double k1,k2, res, fx;
1.132     brouard  4423:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4424:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4425:   int k=0,kmax=10;
                   4426:   double l1;
                   4427: 
                   4428:   fx=func(x);
                   4429:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4430:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4431:     l1=pow(10,l);
                   4432:     delts=delt;
                   4433:     for(k=1 ; k <kmax; k=k+1){
                   4434:       delt = delta*(l1*k);
                   4435:       p2[theta]=x[theta] +delt;
1.145     brouard  4436:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4437:       p2[theta]=x[theta]-delt;
                   4438:       k2=func(p2)-fx;
                   4439:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4440:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4441:       
1.203     brouard  4442: #ifdef DEBUGHESSII
1.126     brouard  4443:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4444:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4445: #endif
                   4446:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4447:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4448:        k=kmax;
                   4449:       }
                   4450:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4451:        k=kmax; l=lmax*10;
1.126     brouard  4452:       }
                   4453:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4454:        delts=delt;
                   4455:       }
1.203     brouard  4456:     } /* End loop k */
1.126     brouard  4457:   }
                   4458:   delti[theta]=delts;
                   4459:   return res; 
                   4460:   
                   4461: }
                   4462: 
1.203     brouard  4463: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4464: {
                   4465:   int i;
1.164     brouard  4466:   int l=1, lmax=20;
1.126     brouard  4467:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4468:   double p2[MAXPARM+1];
1.203     brouard  4469:   int k, kmax=1;
                   4470:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4471: 
                   4472:   int firstime=0;
1.203     brouard  4473:   
1.126     brouard  4474:   fx=func(x);
1.203     brouard  4475:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4476:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4477:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4478:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4479:     k1=func(p2)-fx;
                   4480:   
1.203     brouard  4481:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4482:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4483:     k2=func(p2)-fx;
                   4484:   
1.203     brouard  4485:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4486:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4487:     k3=func(p2)-fx;
                   4488:   
1.203     brouard  4489:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4490:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4491:     k4=func(p2)-fx;
1.203     brouard  4492:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4493:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4494:       firstime=1;
1.203     brouard  4495:       kmax=kmax+10;
1.208     brouard  4496:     }
                   4497:     if(kmax >=10 || firstime ==1){
1.246     brouard  4498:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4499:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4500:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4501:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4502:     }
                   4503: #ifdef DEBUGHESSIJ
                   4504:     v1=hess[thetai][thetai];
                   4505:     v2=hess[thetaj][thetaj];
                   4506:     cv12=res;
                   4507:     /* Computing eigen value of Hessian matrix */
                   4508:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4509:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4510:     if ((lc2 <0) || (lc1 <0) ){
                   4511:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4512:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4513:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4514:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4515:     }
1.126     brouard  4516: #endif
                   4517:   }
                   4518:   return res;
                   4519: }
                   4520: 
1.203     brouard  4521:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4522: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4523: /* { */
                   4524: /*   int i; */
                   4525: /*   int l=1, lmax=20; */
                   4526: /*   double k1,k2,k3,k4,res,fx; */
                   4527: /*   double p2[MAXPARM+1]; */
                   4528: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4529: /*   int k=0,kmax=10; */
                   4530: /*   double l1; */
                   4531:   
                   4532: /*   fx=func(x); */
                   4533: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4534: /*     l1=pow(10,l); */
                   4535: /*     delts=delt; */
                   4536: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4537: /*       delt = delti*(l1*k); */
                   4538: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4539: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4540: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4541: /*       k1=func(p2)-fx; */
                   4542:       
                   4543: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4544: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4545: /*       k2=func(p2)-fx; */
                   4546:       
                   4547: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4548: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4549: /*       k3=func(p2)-fx; */
                   4550:       
                   4551: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4552: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4553: /*       k4=func(p2)-fx; */
                   4554: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4555: /* #ifdef DEBUGHESSIJ */
                   4556: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4557: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4558: /* #endif */
                   4559: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4560: /*     k=kmax; */
                   4561: /*       } */
                   4562: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4563: /*     k=kmax; l=lmax*10; */
                   4564: /*       } */
                   4565: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4566: /*     delts=delt; */
                   4567: /*       } */
                   4568: /*     } /\* End loop k *\/ */
                   4569: /*   } */
                   4570: /*   delti[theta]=delts; */
                   4571: /*   return res;  */
                   4572: /* } */
                   4573: 
                   4574: 
1.126     brouard  4575: /************** Inverse of matrix **************/
                   4576: void ludcmp(double **a, int n, int *indx, double *d) 
                   4577: { 
                   4578:   int i,imax,j,k; 
                   4579:   double big,dum,sum,temp; 
                   4580:   double *vv; 
                   4581:  
                   4582:   vv=vector(1,n); 
                   4583:   *d=1.0; 
                   4584:   for (i=1;i<=n;i++) { 
                   4585:     big=0.0; 
                   4586:     for (j=1;j<=n;j++) 
                   4587:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4588:     if (big == 0.0){
                   4589:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4590:       for (j=1;j<=n;j++) {
                   4591:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4592:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4593:       }
                   4594:       fflush(ficlog);
                   4595:       fclose(ficlog);
                   4596:       nrerror("Singular matrix in routine ludcmp"); 
                   4597:     }
1.126     brouard  4598:     vv[i]=1.0/big; 
                   4599:   } 
                   4600:   for (j=1;j<=n;j++) { 
                   4601:     for (i=1;i<j;i++) { 
                   4602:       sum=a[i][j]; 
                   4603:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4604:       a[i][j]=sum; 
                   4605:     } 
                   4606:     big=0.0; 
                   4607:     for (i=j;i<=n;i++) { 
                   4608:       sum=a[i][j]; 
                   4609:       for (k=1;k<j;k++) 
                   4610:        sum -= a[i][k]*a[k][j]; 
                   4611:       a[i][j]=sum; 
                   4612:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4613:        big=dum; 
                   4614:        imax=i; 
                   4615:       } 
                   4616:     } 
                   4617:     if (j != imax) { 
                   4618:       for (k=1;k<=n;k++) { 
                   4619:        dum=a[imax][k]; 
                   4620:        a[imax][k]=a[j][k]; 
                   4621:        a[j][k]=dum; 
                   4622:       } 
                   4623:       *d = -(*d); 
                   4624:       vv[imax]=vv[j]; 
                   4625:     } 
                   4626:     indx[j]=imax; 
                   4627:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4628:     if (j != n) { 
                   4629:       dum=1.0/(a[j][j]); 
                   4630:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4631:     } 
                   4632:   } 
                   4633:   free_vector(vv,1,n);  /* Doesn't work */
                   4634: ;
                   4635: } 
                   4636: 
                   4637: void lubksb(double **a, int n, int *indx, double b[]) 
                   4638: { 
                   4639:   int i,ii=0,ip,j; 
                   4640:   double sum; 
                   4641:  
                   4642:   for (i=1;i<=n;i++) { 
                   4643:     ip=indx[i]; 
                   4644:     sum=b[ip]; 
                   4645:     b[ip]=b[i]; 
                   4646:     if (ii) 
                   4647:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4648:     else if (sum) ii=i; 
                   4649:     b[i]=sum; 
                   4650:   } 
                   4651:   for (i=n;i>=1;i--) { 
                   4652:     sum=b[i]; 
                   4653:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4654:     b[i]=sum/a[i][i]; 
                   4655:   } 
                   4656: } 
                   4657: 
                   4658: void pstamp(FILE *fichier)
                   4659: {
1.196     brouard  4660:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4661: }
                   4662: 
1.297     brouard  4663: void date2dmy(double date,double *day, double *month, double *year){
                   4664:   double yp=0., yp1=0., yp2=0.;
                   4665:   
                   4666:   yp1=modf(date,&yp);/* extracts integral of date in yp  and
                   4667:                        fractional in yp1 */
                   4668:   *year=yp;
                   4669:   yp2=modf((yp1*12),&yp);
                   4670:   *month=yp;
                   4671:   yp1=modf((yp2*30.5),&yp);
                   4672:   *day=yp;
                   4673:   if(*day==0) *day=1;
                   4674:   if(*month==0) *month=1;
                   4675: }
                   4676: 
1.253     brouard  4677: 
                   4678: 
1.126     brouard  4679: /************ Frequencies ********************/
1.251     brouard  4680: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4681:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4682:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4683: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4684:   
1.265     brouard  4685:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4686:   int iind=0, iage=0;
                   4687:   int mi; /* Effective wave */
                   4688:   int first;
                   4689:   double ***freq; /* Frequencies */
1.268     brouard  4690:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4691:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4692:   double *meanq, *stdq, *idq;
1.226     brouard  4693:   double **meanqt;
                   4694:   double *pp, **prop, *posprop, *pospropt;
                   4695:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4696:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4697:   double agebegin, ageend;
                   4698:     
                   4699:   pp=vector(1,nlstate);
1.251     brouard  4700:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4701:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4702:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4703:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4704:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4705:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4706:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4707:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4708:   strcpy(fileresp,"P_");
                   4709:   strcat(fileresp,fileresu);
                   4710:   /*strcat(fileresphtm,fileresu);*/
                   4711:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4712:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4713:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4714:     exit(0);
                   4715:   }
1.240     brouard  4716:   
1.226     brouard  4717:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4718:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4719:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4720:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4721:     fflush(ficlog);
                   4722:     exit(70); 
                   4723:   }
                   4724:   else{
                   4725:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4726: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4727: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4728:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4729:   }
1.319   ! brouard  4730:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies (weight=%d) and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm, weightopt);
1.240     brouard  4731:   
1.226     brouard  4732:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4733:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4734:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4735:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4736:     fflush(ficlog);
                   4737:     exit(70); 
1.240     brouard  4738:   } else{
1.226     brouard  4739:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.319   ! brouard  4740: ,<hr size=\"2\" color=\"#EC5E5E\"> \n                                  \
1.214     brouard  4741: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4742:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4743:   }
1.319   ! brouard  4744:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>(weight=%d) frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr,weightopt);
1.240     brouard  4745:   
1.253     brouard  4746:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4747:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4748:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4749:   j1=0;
1.126     brouard  4750:   
1.227     brouard  4751:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4752:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4753:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4754:   
                   4755:   
1.226     brouard  4756:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4757:      reference=low_education V1=0,V2=0
                   4758:      med_educ                V1=1 V2=0, 
                   4759:      high_educ               V1=0 V2=1
                   4760:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4761:   */
1.249     brouard  4762:   dateintsum=0;
                   4763:   k2cpt=0;
                   4764: 
1.253     brouard  4765:   if(cptcoveff == 0 )
1.265     brouard  4766:     nl=1;  /* Constant and age model only */
1.253     brouard  4767:   else
                   4768:     nl=2;
1.265     brouard  4769: 
                   4770:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4771:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4772:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4773:    *     freq[s1][s2][iage] =0.
                   4774:    *     Loop on iind
                   4775:    *       ++freq[s1][s2][iage] weighted
                   4776:    *     end iind
                   4777:    *     if covariate and j!0
                   4778:    *       headers Variable on one line
                   4779:    *     endif cov j!=0
                   4780:    *     header of frequency table by age
                   4781:    *     Loop on age
                   4782:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4783:    *       pos+=freq[s1][s2][iage] weighted
                   4784:    *       Loop on s1 initial state
                   4785:    *         fprintf(ficresp
                   4786:    *       end s1
                   4787:    *     end age
                   4788:    *     if j!=0 computes starting values
                   4789:    *     end compute starting values
                   4790:    *   end j1
                   4791:    * end nl 
                   4792:    */
1.253     brouard  4793:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4794:     if(nj==1)
                   4795:       j=0;  /* First pass for the constant */
1.265     brouard  4796:     else{
1.253     brouard  4797:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4798:     }
1.251     brouard  4799:     first=1;
1.265     brouard  4800:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4801:       posproptt=0.;
                   4802:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4803:        scanf("%d", i);*/
                   4804:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4805:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4806:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4807:            freq[i][s2][m]=0;
1.251     brouard  4808:       
                   4809:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4810:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4811:          prop[i][m]=0;
                   4812:        posprop[i]=0;
                   4813:        pospropt[i]=0;
                   4814:       }
1.283     brouard  4815:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4816:         idq[z1]=0.;
                   4817:         meanq[z1]=0.;
                   4818:         stdq[z1]=0.;
1.283     brouard  4819:       }
                   4820:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4821:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4822:       /*         meanqt[m][z1]=0.; */
                   4823:       /*       } */
                   4824:       /* }       */
1.251     brouard  4825:       /* dateintsum=0; */
                   4826:       /* k2cpt=0; */
                   4827:       
1.265     brouard  4828:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4829:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4830:        bool=1;
                   4831:        if(j !=0){
                   4832:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4833:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4834:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4835:                /* if(Tvaraff[z1] ==-20){ */
                   4836:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4837:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4838:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4839:                /* }else  */
                   4840:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4841:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4842:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4843:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4844:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4845:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4846:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4847:                } /* Onlyf fixed */
                   4848:              } /* end z1 */
                   4849:            } /* cptcovn > 0 */
                   4850:          } /* end any */
                   4851:        }/* end j==0 */
1.265     brouard  4852:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4853:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4854:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4855:            m=mw[mi][iind];
                   4856:            if(j!=0){
                   4857:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4858:                for (z1=1; z1<=cptcoveff; z1++) {
                   4859:                  if( Fixed[Tmodelind[z1]]==1){
                   4860:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4861:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4862:                                                                                      value is -1, we don't select. It differs from the 
                   4863:                                                                                      constant and age model which counts them. */
                   4864:                      bool=0; /* not selected */
                   4865:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4866:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4867:                      bool=0;
                   4868:                    }
                   4869:                  }
                   4870:                }
                   4871:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4872:            } /* end j==0 */
                   4873:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4874:            if(bool==1){ /*Selected */
1.251     brouard  4875:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4876:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4877:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4878:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4879:              if(m >=firstpass && m <=lastpass){
                   4880:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4881:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4882:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4883:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4884:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4885:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4886:                if (m<lastpass) {
                   4887:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4888:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4889:                  if(s[m][iind]==-1)
                   4890:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4891:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.311     brouard  4892:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean on known values only */
                   4893:                    if(!isnan(covar[ncovcol+z1][iind])){
                   4894:                        idq[z1]=idq[z1]+weight[iind];
                   4895:                        meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4896:                        /* stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; *//*error*/
                   4897:                        stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4898:                    }
1.284     brouard  4899:                  }
1.251     brouard  4900:                  /* if((int)agev[m][iind] == 55) */
                   4901:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4902:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4903:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4904:                }
1.251     brouard  4905:              } /* end if between passes */  
                   4906:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4907:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4908:                k2cpt++;
                   4909:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4910:              }
1.251     brouard  4911:            }else{
                   4912:              bool=1;
                   4913:            }/* end bool 2 */
                   4914:          } /* end m */
1.284     brouard  4915:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4916:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4917:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4918:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4919:          /* } */
1.251     brouard  4920:        } /* end bool */
                   4921:       } /* end iind = 1 to imx */
1.319   ! brouard  4922:       /* prop[s][age] is fed for any initial and valid live state as well as
1.251     brouard  4923:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4924:       
                   4925:       
                   4926:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4927:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4928:         pstamp(ficresp);
1.251     brouard  4929:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4930:         pstamp(ficresp);
1.251     brouard  4931:        printf( "\n#********** Variable "); 
                   4932:        fprintf(ficresp, "\n#********** Variable "); 
                   4933:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4934:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4935:        fprintf(ficlog, "\n#********** Variable "); 
                   4936:        for (z1=1; z1<=cptcoveff; z1++){
                   4937:          if(!FixedV[Tvaraff[z1]]){
                   4938:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4939:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4940:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4941:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4942:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4943:          }else{
1.251     brouard  4944:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4945:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4946:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4947:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4948:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4949:          }
                   4950:        }
                   4951:        printf( "**********\n#");
                   4952:        fprintf(ficresp, "**********\n#");
                   4953:        fprintf(ficresphtm, "**********</h3>\n");
                   4954:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4955:        fprintf(ficlog, "**********\n");
                   4956:       }
1.284     brouard  4957:       /*
                   4958:        Printing means of quantitative variables if any
                   4959:       */
                   4960:       for (z1=1; z1<= nqfveff; z1++) {
1.311     brouard  4961:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.3g (weighted) individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.312     brouard  4962:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
1.284     brouard  4963:        if(weightopt==1){
                   4964:          printf(" Weighted mean and standard deviation of");
                   4965:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4966:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4967:        }
1.311     brouard  4968:        /* mu = \frac{w x}{\sum w}
                   4969:            var = \frac{\sum w (x-mu)^2}{\sum w} = \frac{w x^2}{\sum w} - mu^2 
                   4970:        */
                   4971:        printf(" fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   4972:        fprintf(ficlog," fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   4973:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.3g (weighted) representatives of the population : %8.5g (%8.5g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
1.284     brouard  4974:       }
                   4975:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4976:       /*       for(m=1;m<=lastpass;m++){ */
                   4977:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4978:       /*   } */
                   4979:       /* } */
1.283     brouard  4980: 
1.251     brouard  4981:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4982:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4983:         fprintf(ficresp, " Age");
                   4984:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4985:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4986:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4987:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4988:       }
1.265     brouard  4989:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4990:       fprintf(ficresphtm, "\n");
                   4991:       
                   4992:       /* Header of frequency table by age */
                   4993:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4994:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4995:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4996:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4997:          if(s2!=0 && m!=0)
                   4998:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4999:        }
1.226     brouard  5000:       }
1.251     brouard  5001:       fprintf(ficresphtmfr, "\n");
                   5002:     
                   5003:       /* For each age */
                   5004:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   5005:        fprintf(ficresphtm,"<tr>");
                   5006:        if(iage==iagemax+1){
                   5007:          fprintf(ficlog,"1");
                   5008:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   5009:        }else if(iage==iagemax+2){
                   5010:          fprintf(ficlog,"0");
                   5011:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   5012:        }else if(iage==iagemax+3){
                   5013:          fprintf(ficlog,"Total");
                   5014:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   5015:        }else{
1.240     brouard  5016:          if(first==1){
1.251     brouard  5017:            first=0;
                   5018:            printf("See log file for details...\n");
                   5019:          }
                   5020:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   5021:          fprintf(ficlog,"Age %d", iage);
                   5022:        }
1.265     brouard  5023:        for(s1=1; s1 <=nlstate ; s1++){
                   5024:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   5025:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  5026:        }
1.265     brouard  5027:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  5028:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  5029:            pos += freq[s1][m][iage];
                   5030:          if(pp[s1]>=1.e-10){
1.251     brouard  5031:            if(first==1){
1.265     brouard  5032:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  5033:            }
1.265     brouard  5034:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  5035:          }else{
                   5036:            if(first==1)
1.265     brouard  5037:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   5038:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  5039:          }
                   5040:        }
                   5041:       
1.265     brouard  5042:        for(s1=1; s1 <=nlstate ; s1++){ 
                   5043:          /* posprop[s1]=0; */
                   5044:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   5045:            pp[s1] += freq[s1][m][iage];
                   5046:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   5047:       
                   5048:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   5049:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   5050:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   5051:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   5052:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   5053:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   5054:        }
                   5055:        
                   5056:        /* Writing ficresp */
                   5057:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   5058:           if( iage <= iagemax){
                   5059:            fprintf(ficresp," %d",iage);
                   5060:           }
                   5061:         }else if( nj==2){
                   5062:           if( iage <= iagemax){
                   5063:            fprintf(ficresp," %d",iage);
                   5064:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   5065:           }
1.240     brouard  5066:        }
1.265     brouard  5067:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  5068:          if(pos>=1.e-5){
1.251     brouard  5069:            if(first==1)
1.265     brouard  5070:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   5071:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  5072:          }else{
                   5073:            if(first==1)
1.265     brouard  5074:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   5075:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  5076:          }
                   5077:          if( iage <= iagemax){
                   5078:            if(pos>=1.e-5){
1.265     brouard  5079:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   5080:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   5081:               }else if( nj==2){
                   5082:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   5083:               }
                   5084:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   5085:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   5086:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   5087:            } else{
                   5088:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   5089:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  5090:            }
1.240     brouard  5091:          }
1.265     brouard  5092:          pospropt[s1] +=posprop[s1];
                   5093:        } /* end loop s1 */
1.251     brouard  5094:        /* pospropt=0.; */
1.265     brouard  5095:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  5096:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  5097:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  5098:              if(first==1){
1.265     brouard  5099:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  5100:              }
1.265     brouard  5101:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   5102:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  5103:            }
1.265     brouard  5104:            if(s1!=0 && m!=0)
                   5105:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  5106:          }
1.265     brouard  5107:        } /* end loop s1 */
1.251     brouard  5108:        posproptt=0.; 
1.265     brouard  5109:        for(s1=1; s1 <=nlstate; s1++){
                   5110:          posproptt += pospropt[s1];
1.251     brouard  5111:        }
                   5112:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  5113:        fprintf(ficresphtm,"</tr>\n");
                   5114:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   5115:          if(iage <= iagemax)
                   5116:            fprintf(ficresp,"\n");
1.240     brouard  5117:        }
1.251     brouard  5118:        if(first==1)
                   5119:          printf("Others in log...\n");
                   5120:        fprintf(ficlog,"\n");
                   5121:       } /* end loop age iage */
1.265     brouard  5122:       
1.251     brouard  5123:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  5124:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  5125:        if(posproptt < 1.e-5){
1.265     brouard  5126:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  5127:        }else{
1.265     brouard  5128:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  5129:        }
1.226     brouard  5130:       }
1.251     brouard  5131:       fprintf(ficresphtm,"</tr>\n");
                   5132:       fprintf(ficresphtm,"</table>\n");
                   5133:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  5134:       if(posproptt < 1.e-5){
1.251     brouard  5135:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   5136:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  5137:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   5138:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  5139:        invalidvarcomb[j1]=1;
1.226     brouard  5140:       }else{
1.251     brouard  5141:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   5142:        invalidvarcomb[j1]=0;
1.226     brouard  5143:       }
1.251     brouard  5144:       fprintf(ficresphtmfr,"</table>\n");
                   5145:       fprintf(ficlog,"\n");
                   5146:       if(j!=0){
                   5147:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  5148:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  5149:          for(k=1; k <=(nlstate+ndeath); k++){
                   5150:            if (k != i) {
1.265     brouard  5151:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  5152:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  5153:                  if(j1==1){ /* All dummy covariates to zero */
                   5154:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   5155:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  5156:                    printf("%d%d ",i,k);
                   5157:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  5158:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   5159:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   5160:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  5161:                  }
1.253     brouard  5162:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   5163:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   5164:                    x[iage]= (double)iage;
                   5165:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  5166:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  5167:                  }
1.268     brouard  5168:                  /* Some are not finite, but linreg will ignore these ages */
                   5169:                  no=0;
1.253     brouard  5170:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  5171:                  pstart[s1]=b;
                   5172:                  pstart[s1-1]=a;
1.252     brouard  5173:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   5174:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   5175:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  5176:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  5177:                  printf("%d%d ",i,k);
                   5178:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  5179:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  5180:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   5181:                  ;
                   5182:                }
                   5183:                /* printf("%12.7f )", param[i][jj][k]); */
                   5184:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5185:                s1++; 
1.251     brouard  5186:              } /* end jj */
                   5187:            } /* end k!= i */
                   5188:          } /* end k */
1.265     brouard  5189:        } /* end i, s1 */
1.251     brouard  5190:       } /* end j !=0 */
                   5191:     } /* end selected combination of covariate j1 */
                   5192:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   5193:       printf("#Freqsummary: Starting values for the constants:\n");
                   5194:       fprintf(ficlog,"\n");
1.265     brouard  5195:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  5196:        for(k=1; k <=(nlstate+ndeath); k++){
                   5197:          if (k != i) {
                   5198:            printf("%d%d ",i,k);
                   5199:            fprintf(ficlog,"%d%d ",i,k);
                   5200:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  5201:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  5202:              if(jj==1){ /* Age has to be done */
1.265     brouard  5203:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   5204:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   5205:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  5206:              }
                   5207:              /* printf("%12.7f )", param[i][jj][k]); */
                   5208:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5209:              s1++; 
1.250     brouard  5210:            }
1.251     brouard  5211:            printf("\n");
                   5212:            fprintf(ficlog,"\n");
1.250     brouard  5213:          }
                   5214:        }
1.284     brouard  5215:       } /* end of state i */
1.251     brouard  5216:       printf("#Freqsummary\n");
                   5217:       fprintf(ficlog,"\n");
1.265     brouard  5218:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   5219:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   5220:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   5221:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5222:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5223:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   5224:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   5225:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  5226:          /* } */
                   5227:        }
1.265     brouard  5228:       } /* end loop s1 */
1.251     brouard  5229:       
                   5230:       printf("\n");
                   5231:       fprintf(ficlog,"\n");
                   5232:     } /* end j=0 */
1.249     brouard  5233:   } /* end j */
1.252     brouard  5234: 
1.253     brouard  5235:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  5236:     for(i=1, jk=1; i <=nlstate; i++){
                   5237:       for(j=1; j <=nlstate+ndeath; j++){
                   5238:        if(j!=i){
                   5239:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   5240:          printf("%1d%1d",i,j);
                   5241:          fprintf(ficparo,"%1d%1d",i,j);
                   5242:          for(k=1; k<=ncovmodel;k++){
                   5243:            /*    printf(" %lf",param[i][j][k]); */
                   5244:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   5245:            p[jk]=pstart[jk];
                   5246:            printf(" %f ",pstart[jk]);
                   5247:            fprintf(ficparo," %f ",pstart[jk]);
                   5248:            jk++;
                   5249:          }
                   5250:          printf("\n");
                   5251:          fprintf(ficparo,"\n");
                   5252:        }
                   5253:       }
                   5254:     }
                   5255:   } /* end mle=-2 */
1.226     brouard  5256:   dateintmean=dateintsum/k2cpt; 
1.296     brouard  5257:   date2dmy(dateintmean,&jintmean,&mintmean,&aintmean);
1.240     brouard  5258:   
1.226     brouard  5259:   fclose(ficresp);
                   5260:   fclose(ficresphtm);
                   5261:   fclose(ficresphtmfr);
1.283     brouard  5262:   free_vector(idq,1,nqfveff);
1.226     brouard  5263:   free_vector(meanq,1,nqfveff);
1.284     brouard  5264:   free_vector(stdq,1,nqfveff);
1.226     brouard  5265:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  5266:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   5267:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  5268:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5269:   free_vector(pospropt,1,nlstate);
                   5270:   free_vector(posprop,1,nlstate);
1.251     brouard  5271:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5272:   free_vector(pp,1,nlstate);
                   5273:   /* End of freqsummary */
                   5274: }
1.126     brouard  5275: 
1.268     brouard  5276: /* Simple linear regression */
                   5277: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   5278: 
                   5279:   /* y=a+bx regression */
                   5280:   double   sumx = 0.0;                        /* sum of x                      */
                   5281:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   5282:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   5283:   double   sumy = 0.0;                        /* sum of y                      */
                   5284:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   5285:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   5286:   double yhat;
                   5287:   
                   5288:   double denom=0;
                   5289:   int i;
                   5290:   int ne=*no;
                   5291:   
                   5292:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5293:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5294:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5295:       continue;
                   5296:     }
                   5297:     ne=ne+1;
                   5298:     sumx  += x[i];       
                   5299:     sumx2 += x[i]*x[i];  
                   5300:     sumxy += x[i] * y[i];
                   5301:     sumy  += y[i];      
                   5302:     sumy2 += y[i]*y[i]; 
                   5303:     denom = (ne * sumx2 - sumx*sumx);
                   5304:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5305:   } 
                   5306:   
                   5307:   denom = (ne * sumx2 - sumx*sumx);
                   5308:   if (denom == 0) {
                   5309:     // vertical, slope m is infinity
                   5310:     *b = INFINITY;
                   5311:     *a = 0;
                   5312:     if (r) *r = 0;
                   5313:     return 1;
                   5314:   }
                   5315:   
                   5316:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5317:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5318:   if (r!=NULL) {
                   5319:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5320:       sqrt((sumx2 - sumx*sumx/ne) *
                   5321:           (sumy2 - sumy*sumy/ne));
                   5322:   }
                   5323:   *no=ne;
                   5324:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5325:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5326:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5327:       continue;
                   5328:     }
                   5329:     ne=ne+1;
                   5330:     yhat = y[i] - *a -*b* x[i];
                   5331:     sume2  += yhat * yhat ;       
                   5332:     
                   5333:     denom = (ne * sumx2 - sumx*sumx);
                   5334:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5335:   } 
                   5336:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5337:   *sa= *sb * sqrt(sumx2/ne);
                   5338:   
                   5339:   return 0; 
                   5340: }
                   5341: 
1.126     brouard  5342: /************ Prevalence ********************/
1.227     brouard  5343: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5344: {  
                   5345:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5346:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5347:      We still use firstpass and lastpass as another selection.
                   5348:   */
1.126     brouard  5349:  
1.227     brouard  5350:   int i, m, jk, j1, bool, z1,j, iv;
                   5351:   int mi; /* Effective wave */
                   5352:   int iage;
                   5353:   double agebegin, ageend;
                   5354: 
                   5355:   double **prop;
                   5356:   double posprop; 
                   5357:   double  y2; /* in fractional years */
                   5358:   int iagemin, iagemax;
                   5359:   int first; /** to stop verbosity which is redirected to log file */
                   5360: 
                   5361:   iagemin= (int) agemin;
                   5362:   iagemax= (int) agemax;
                   5363:   /*pp=vector(1,nlstate);*/
1.251     brouard  5364:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5365:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5366:   j1=0;
1.222     brouard  5367:   
1.227     brouard  5368:   /*j=cptcoveff;*/
                   5369:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5370:   
1.288     brouard  5371:   first=0;
1.227     brouard  5372:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5373:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5374:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5375:        prop[i][iage]=0.0;
                   5376:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5377:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5378:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5379:     
                   5380:     for (i=1; i<=imx; i++) { /* Each individual */
                   5381:       bool=1;
                   5382:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5383:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5384:        m=mw[mi][i];
                   5385:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5386:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5387:        for (z1=1; z1<=cptcoveff; z1++){
                   5388:          if( Fixed[Tmodelind[z1]]==1){
                   5389:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5390:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5391:              bool=0;
                   5392:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5393:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5394:              bool=0;
                   5395:            }
                   5396:        }
                   5397:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5398:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5399:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5400:          if(m >=firstpass && m <=lastpass){
                   5401:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5402:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5403:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5404:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5405:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5406:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5407:                exit(1);
                   5408:              }
                   5409:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5410:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5411:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5412:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5413:              } /* end valid statuses */ 
                   5414:            } /* end selection of dates */
                   5415:          } /* end selection of waves */
                   5416:        } /* end bool */
                   5417:       } /* end wave */
                   5418:     } /* end individual */
                   5419:     for(i=iagemin; i <= iagemax+3; i++){  
                   5420:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5421:        posprop += prop[jk][i]; 
                   5422:       } 
                   5423:       
                   5424:       for(jk=1; jk <=nlstate ; jk++){      
                   5425:        if( i <=  iagemax){ 
                   5426:          if(posprop>=1.e-5){ 
                   5427:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5428:          } else{
1.288     brouard  5429:            if(!first){
                   5430:              first=1;
1.266     brouard  5431:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5432:            }else{
1.288     brouard  5433:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5434:            }
                   5435:          }
                   5436:        } 
                   5437:       }/* end jk */ 
                   5438:     }/* end i */ 
1.222     brouard  5439:      /*} *//* end i1 */
1.227     brouard  5440:   } /* end j1 */
1.222     brouard  5441:   
1.227     brouard  5442:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5443:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5444:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5445: }  /* End of prevalence */
1.126     brouard  5446: 
                   5447: /************* Waves Concatenation ***************/
                   5448: 
                   5449: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5450: {
1.298     brouard  5451:   /* Concatenates waves: wav[i] is the number of effective (useful waves in the sense that a non interview is useless) of individual i.
1.126     brouard  5452:      Death is a valid wave (if date is known).
                   5453:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5454:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
1.298     brouard  5455:      and mw[mi+1][i]. dh depends on stepm. s[m][i] exists for any wave from firstpass to lastpass
1.227     brouard  5456:   */
1.126     brouard  5457: 
1.224     brouard  5458:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5459:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5460:      double sum=0., jmean=0.;*/
1.224     brouard  5461:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5462:   int j, k=0,jk, ju, jl;
                   5463:   double sum=0.;
                   5464:   first=0;
1.214     brouard  5465:   firstwo=0;
1.217     brouard  5466:   firsthree=0;
1.218     brouard  5467:   firstfour=0;
1.164     brouard  5468:   jmin=100000;
1.126     brouard  5469:   jmax=-1;
                   5470:   jmean=0.;
1.224     brouard  5471: 
                   5472: /* Treating live states */
1.214     brouard  5473:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5474:     mi=0;  /* First valid wave */
1.227     brouard  5475:     mli=0; /* Last valid wave */
1.309     brouard  5476:     m=firstpass;  /* Loop on waves */
                   5477:     while(s[m][i] <= nlstate){  /* a live state or unknown state  */
1.227     brouard  5478:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5479:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5480:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
1.309     brouard  5481:        mw[++mi][i]=m; /* Valid wave: incrementing mi and updating mi; mw[mi] is the wave number of mi_th valid transition   */
1.227     brouard  5482:        mli=m;
1.224     brouard  5483:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5484:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5485:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5486:       }
1.309     brouard  5487:       else{ /* m = lastpass, eventual special issue with warning */
1.224     brouard  5488: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5489:        break;
1.224     brouard  5490: #else
1.317     brouard  5491:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){ /* no death date and known date of interview, case -2 (vital status unknown is warned later */
1.227     brouard  5492:          if(firsthree == 0){
1.302     brouard  5493:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5494:            firsthree=1;
1.317     brouard  5495:          }else if(firsthree >=1 && firsthree < 10){
                   5496:            fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
                   5497:            firsthree++;
                   5498:          }else if(firsthree == 10){
                   5499:            printf("Information, too many Information flags: no more reported to log either\n");
                   5500:            fprintf(ficlog,"Information, too many Information flags: no more reported to log either\n");
                   5501:            firsthree++;
                   5502:          }else{
                   5503:            firsthree++;
1.227     brouard  5504:          }
1.309     brouard  5505:          mw[++mi][i]=m; /* Valid transition with unknown status */
1.227     brouard  5506:          mli=m;
                   5507:        }
                   5508:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5509:          nbwarn++;
1.309     brouard  5510:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified?not a transition */
1.227     brouard  5511:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5512:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5513:          }
                   5514:          break;
                   5515:        }
                   5516:        break;
1.224     brouard  5517: #endif
1.227     brouard  5518:       }/* End m >= lastpass */
1.126     brouard  5519:     }/* end while */
1.224     brouard  5520: 
1.227     brouard  5521:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5522:     /* After last pass */
1.224     brouard  5523: /* Treating death states */
1.214     brouard  5524:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5525:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5526:       /* } */
1.126     brouard  5527:       mi++;    /* Death is another wave */
                   5528:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5529:       /* Only death is a correct wave */
1.126     brouard  5530:       mw[mi][i]=m;
1.257     brouard  5531:     } /* else not in a death state */
1.224     brouard  5532: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5533:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5534:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.309     brouard  5535:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* month of death occured before last wave month and status should have been death instead of -1 */
1.227     brouard  5536:          nbwarn++;
                   5537:          if(firstfiv==0){
1.309     brouard  5538:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5539:            firstfiv=1;
                   5540:          }else{
1.309     brouard  5541:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5542:          }
1.309     brouard  5543:            s[m][i]=nlstate+1; /* Fixing the status as death. Be careful if multiple death states */
                   5544:        }else{ /* Month of Death occured afer last wave month, potential bias */
1.227     brouard  5545:          nberr++;
                   5546:          if(firstwo==0){
1.309     brouard  5547:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5548:            firstwo=1;
                   5549:          }
1.309     brouard  5550:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5551:        }
1.257     brouard  5552:       }else{ /* if date of interview is unknown */
1.227     brouard  5553:        /* death is known but not confirmed by death status at any wave */
                   5554:        if(firstfour==0){
1.309     brouard  5555:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5556:          firstfour=1;
                   5557:        }
1.309     brouard  5558:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d  with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.214     brouard  5559:       }
1.224     brouard  5560:     } /* end if date of death is known */
                   5561: #endif
1.309     brouard  5562:     wav[i]=mi; /* mi should be the last effective wave (or mli),  */
                   5563:     /* wav[i]=mw[mi][i];   */
1.126     brouard  5564:     if(mi==0){
                   5565:       nbwarn++;
                   5566:       if(first==0){
1.227     brouard  5567:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5568:        first=1;
1.126     brouard  5569:       }
                   5570:       if(first==1){
1.227     brouard  5571:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5572:       }
                   5573:     } /* end mi==0 */
                   5574:   } /* End individuals */
1.214     brouard  5575:   /* wav and mw are no more changed */
1.223     brouard  5576:        
1.317     brouard  5577:   printf("Information, you have to check %d informations which haven't been logged!\n",firsthree);
                   5578:   fprintf(ficlog,"Information, you have to check %d informations which haven't been logged!\n",firsthree);
                   5579: 
                   5580: 
1.126     brouard  5581:   for(i=1; i<=imx; i++){
                   5582:     for(mi=1; mi<wav[i];mi++){
                   5583:       if (stepm <=0)
1.227     brouard  5584:        dh[mi][i]=1;
1.126     brouard  5585:       else{
1.260     brouard  5586:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5587:          if (agedc[i] < 2*AGESUP) {
                   5588:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5589:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5590:            else if(j<0){
                   5591:              nberr++;
                   5592:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5593:              j=1; /* Temporary Dangerous patch */
                   5594:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5595:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5596:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5597:            }
                   5598:            k=k+1;
                   5599:            if (j >= jmax){
                   5600:              jmax=j;
                   5601:              ijmax=i;
                   5602:            }
                   5603:            if (j <= jmin){
                   5604:              jmin=j;
                   5605:              ijmin=i;
                   5606:            }
                   5607:            sum=sum+j;
                   5608:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5609:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5610:          }
                   5611:        }
                   5612:        else{
                   5613:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5614: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5615:                                        
1.227     brouard  5616:          k=k+1;
                   5617:          if (j >= jmax) {
                   5618:            jmax=j;
                   5619:            ijmax=i;
                   5620:          }
                   5621:          else if (j <= jmin){
                   5622:            jmin=j;
                   5623:            ijmin=i;
                   5624:          }
                   5625:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5626:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5627:          if(j<0){
                   5628:            nberr++;
                   5629:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5630:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5631:          }
                   5632:          sum=sum+j;
                   5633:        }
                   5634:        jk= j/stepm;
                   5635:        jl= j -jk*stepm;
                   5636:        ju= j -(jk+1)*stepm;
                   5637:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5638:          if(jl==0){
                   5639:            dh[mi][i]=jk;
                   5640:            bh[mi][i]=0;
                   5641:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5642:                  * to avoid the price of an extra matrix product in likelihood */
                   5643:            dh[mi][i]=jk+1;
                   5644:            bh[mi][i]=ju;
                   5645:          }
                   5646:        }else{
                   5647:          if(jl <= -ju){
                   5648:            dh[mi][i]=jk;
                   5649:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5650:                                 * is higher than the multiple of stepm and negative otherwise.
                   5651:                                 */
                   5652:          }
                   5653:          else{
                   5654:            dh[mi][i]=jk+1;
                   5655:            bh[mi][i]=ju;
                   5656:          }
                   5657:          if(dh[mi][i]==0){
                   5658:            dh[mi][i]=1; /* At least one step */
                   5659:            bh[mi][i]=ju; /* At least one step */
                   5660:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5661:          }
                   5662:        } /* end if mle */
1.126     brouard  5663:       }
                   5664:     } /* end wave */
                   5665:   }
                   5666:   jmean=sum/k;
                   5667:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5668:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5669: }
1.126     brouard  5670: 
                   5671: /*********** Tricode ****************************/
1.220     brouard  5672:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5673:  {
                   5674:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5675:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5676:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5677:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5678:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5679:     */
1.130     brouard  5680: 
1.242     brouard  5681:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5682:    int modmaxcovj=0; /* Modality max of covariates j */
                   5683:    int cptcode=0; /* Modality max of covariates j */
                   5684:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5685: 
                   5686: 
1.242     brouard  5687:    /* cptcoveff=0;  */
                   5688:    /* *cptcov=0; */
1.126     brouard  5689:  
1.242     brouard  5690:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5691:    for (k=1; k <= maxncov; k++)
                   5692:      for(j=1; j<=2; j++)
                   5693:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5694: 
1.242     brouard  5695:    /* Loop on covariates without age and products and no quantitative variable */
                   5696:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5697:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5698:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5699:        switch(Fixed[k]) {
                   5700:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
1.311     brouard  5701:         modmaxcovj=0;
                   5702:         modmincovj=0;
1.242     brouard  5703:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5704:           ij=(int)(covar[Tvar[k]][i]);
                   5705:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5706:            * If product of Vn*Vm, still boolean *:
                   5707:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5708:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5709:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5710:              modality of the nth covariate of individual i. */
                   5711:           if (ij > modmaxcovj)
                   5712:             modmaxcovj=ij; 
                   5713:           else if (ij < modmincovj) 
                   5714:             modmincovj=ij; 
1.287     brouard  5715:           if (ij <0 || ij >1 ){
1.311     brouard  5716:             printf("ERROR, IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5717:             fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5718:             fflush(ficlog);
                   5719:             exit(1);
1.287     brouard  5720:           }
                   5721:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5722:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5723:             exit(1);
                   5724:           }else
                   5725:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5726:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5727:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5728:           /* getting the maximum value of the modality of the covariate
                   5729:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5730:              female ies 1, then modmaxcovj=1.
                   5731:           */
                   5732:         } /* end for loop on individuals i */
                   5733:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5734:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5735:         cptcode=modmaxcovj;
                   5736:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5737:         /*for (i=0; i<=cptcode; i++) {*/
                   5738:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5739:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5740:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5741:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5742:             if( j != -1){
                   5743:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5744:                                  covariate for which somebody answered excluding 
                   5745:                                  undefined. Usually 2: 0 and 1. */
                   5746:             }
                   5747:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5748:                                     covariate for which somebody answered including 
                   5749:                                     undefined. Usually 3: -1, 0 and 1. */
                   5750:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5751:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5752:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5753:                        
1.242     brouard  5754:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5755:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5756:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5757:         /* modmincovj=3; modmaxcovj = 7; */
                   5758:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5759:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5760:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5761:         /* nbcode[Tvar[j]][ij]=k; */
                   5762:         /* nbcode[Tvar[j]][1]=0; */
                   5763:         /* nbcode[Tvar[j]][2]=1; */
                   5764:         /* nbcode[Tvar[j]][3]=2; */
                   5765:         /* To be continued (not working yet). */
                   5766:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5767: 
                   5768:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5769:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5770:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5771:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5772:         /*, could be restored in the future */
                   5773:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5774:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5775:             break;
                   5776:           }
                   5777:           ij++;
1.287     brouard  5778:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5779:           cptcode = ij; /* New max modality for covar j */
                   5780:         } /* end of loop on modality i=-1 to 1 or more */
                   5781:         break;
                   5782:        case 1: /* Testing on varying covariate, could be simple and
                   5783:                * should look at waves or product of fixed *
                   5784:                * varying. No time to test -1, assuming 0 and 1 only */
                   5785:         ij=0;
                   5786:         for(i=0; i<=1;i++){
                   5787:           nbcode[Tvar[k]][++ij]=i;
                   5788:         }
                   5789:         break;
                   5790:        default:
                   5791:         break;
                   5792:        } /* end switch */
                   5793:      } /* end dummy test */
1.311     brouard  5794:      if(Dummy[k]==1 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5795:        for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5796:         if(isnan(covar[Tvar[k]][i])){
                   5797:           printf("ERROR, IMaCh doesn't treat fixed quantitative covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5798:           fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5799:           fflush(ficlog);
                   5800:           exit(1);
                   5801:          }
                   5802:        }
                   5803:      }
1.287     brouard  5804:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5805:   
                   5806:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5807:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5808:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5809:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5810:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5811:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5812:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5813:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5814:   
                   5815:    ij=0;
                   5816:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5817:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5818:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5819:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5820:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5821:        /* If product not in single variable we don't print results */
                   5822:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5823:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5824:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5825:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5826:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5827:        if(Fixed[k]!=0)
                   5828:         anyvaryingduminmodel=1;
                   5829:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5830:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5831:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5832:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5833:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5834:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5835:      } 
                   5836:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5837:    /* ij--; */
                   5838:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5839:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5840:                * because they can be excluded from the model and real
                   5841:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5842:    for(j=ij+1; j<= cptcovt; j++){
                   5843:      Tvaraff[j]=0;
                   5844:      Tmodelind[j]=0;
                   5845:    }
                   5846:    for(j=ntveff+1; j<= cptcovt; j++){
                   5847:      TmodelInvind[j]=0;
                   5848:    }
                   5849:    /* To be sorted */
                   5850:    ;
                   5851:  }
1.126     brouard  5852: 
1.145     brouard  5853: 
1.126     brouard  5854: /*********** Health Expectancies ****************/
                   5855: 
1.235     brouard  5856:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5857: 
                   5858: {
                   5859:   /* Health expectancies, no variances */
1.164     brouard  5860:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5861:   int nhstepma, nstepma; /* Decreasing with age */
                   5862:   double age, agelim, hf;
                   5863:   double ***p3mat;
                   5864:   double eip;
                   5865: 
1.238     brouard  5866:   /* pstamp(ficreseij); */
1.126     brouard  5867:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5868:   fprintf(ficreseij,"# Age");
                   5869:   for(i=1; i<=nlstate;i++){
                   5870:     for(j=1; j<=nlstate;j++){
                   5871:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5872:     }
                   5873:     fprintf(ficreseij," e%1d. ",i);
                   5874:   }
                   5875:   fprintf(ficreseij,"\n");
                   5876: 
                   5877:   
                   5878:   if(estepm < stepm){
                   5879:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5880:   }
                   5881:   else  hstepm=estepm;   
                   5882:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5883:    * This is mainly to measure the difference between two models: for example
                   5884:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5885:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5886:    * progression in between and thus overestimating or underestimating according
                   5887:    * to the curvature of the survival function. If, for the same date, we 
                   5888:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5889:    * to compare the new estimate of Life expectancy with the same linear 
                   5890:    * hypothesis. A more precise result, taking into account a more precise
                   5891:    * curvature will be obtained if estepm is as small as stepm. */
                   5892: 
                   5893:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5894:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5895:      nhstepm is the number of hstepm from age to agelim 
                   5896:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5897:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5898:      and note for a fixed period like estepm months */
                   5899:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5900:      survival function given by stepm (the optimization length). Unfortunately it
                   5901:      means that if the survival funtion is printed only each two years of age and if
                   5902:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5903:      results. So we changed our mind and took the option of the best precision.
                   5904:   */
                   5905:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5906: 
                   5907:   agelim=AGESUP;
                   5908:   /* If stepm=6 months */
                   5909:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5910:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5911:     
                   5912: /* nhstepm age range expressed in number of stepm */
                   5913:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5914:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5915:   /* if (stepm >= YEARM) hstepm=1;*/
                   5916:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5917:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5918: 
                   5919:   for (age=bage; age<=fage; age ++){ 
                   5920:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5921:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5922:     /* if (stepm >= YEARM) hstepm=1;*/
                   5923:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5924: 
                   5925:     /* If stepm=6 months */
                   5926:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5927:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5928:     
1.235     brouard  5929:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5930:     
                   5931:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5932:     
                   5933:     printf("%d|",(int)age);fflush(stdout);
                   5934:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5935:     
                   5936:     /* Computing expectancies */
                   5937:     for(i=1; i<=nlstate;i++)
                   5938:       for(j=1; j<=nlstate;j++)
                   5939:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5940:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5941:          
                   5942:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5943: 
                   5944:        }
                   5945: 
                   5946:     fprintf(ficreseij,"%3.0f",age );
                   5947:     for(i=1; i<=nlstate;i++){
                   5948:       eip=0;
                   5949:       for(j=1; j<=nlstate;j++){
                   5950:        eip +=eij[i][j][(int)age];
                   5951:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5952:       }
                   5953:       fprintf(ficreseij,"%9.4f", eip );
                   5954:     }
                   5955:     fprintf(ficreseij,"\n");
                   5956:     
                   5957:   }
                   5958:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5959:   printf("\n");
                   5960:   fprintf(ficlog,"\n");
                   5961:   
                   5962: }
                   5963: 
1.235     brouard  5964:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5965: 
                   5966: {
                   5967:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5968:      to initial status i, ei. .
1.126     brouard  5969:   */
                   5970:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5971:   int nhstepma, nstepma; /* Decreasing with age */
                   5972:   double age, agelim, hf;
                   5973:   double ***p3matp, ***p3matm, ***varhe;
                   5974:   double **dnewm,**doldm;
                   5975:   double *xp, *xm;
                   5976:   double **gp, **gm;
                   5977:   double ***gradg, ***trgradg;
                   5978:   int theta;
                   5979: 
                   5980:   double eip, vip;
                   5981: 
                   5982:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5983:   xp=vector(1,npar);
                   5984:   xm=vector(1,npar);
                   5985:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5986:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5987:   
                   5988:   pstamp(ficresstdeij);
                   5989:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5990:   fprintf(ficresstdeij,"# Age");
                   5991:   for(i=1; i<=nlstate;i++){
                   5992:     for(j=1; j<=nlstate;j++)
                   5993:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5994:     fprintf(ficresstdeij," e%1d. ",i);
                   5995:   }
                   5996:   fprintf(ficresstdeij,"\n");
                   5997: 
                   5998:   pstamp(ficrescveij);
                   5999:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   6000:   fprintf(ficrescveij,"# Age");
                   6001:   for(i=1; i<=nlstate;i++)
                   6002:     for(j=1; j<=nlstate;j++){
                   6003:       cptj= (j-1)*nlstate+i;
                   6004:       for(i2=1; i2<=nlstate;i2++)
                   6005:        for(j2=1; j2<=nlstate;j2++){
                   6006:          cptj2= (j2-1)*nlstate+i2;
                   6007:          if(cptj2 <= cptj)
                   6008:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   6009:        }
                   6010:     }
                   6011:   fprintf(ficrescveij,"\n");
                   6012:   
                   6013:   if(estepm < stepm){
                   6014:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   6015:   }
                   6016:   else  hstepm=estepm;   
                   6017:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   6018:    * This is mainly to measure the difference between two models: for example
                   6019:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   6020:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   6021:    * progression in between and thus overestimating or underestimating according
                   6022:    * to the curvature of the survival function. If, for the same date, we 
                   6023:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   6024:    * to compare the new estimate of Life expectancy with the same linear 
                   6025:    * hypothesis. A more precise result, taking into account a more precise
                   6026:    * curvature will be obtained if estepm is as small as stepm. */
                   6027: 
                   6028:   /* For example we decided to compute the life expectancy with the smallest unit */
                   6029:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6030:      nhstepm is the number of hstepm from age to agelim 
                   6031:      nstepm is the number of stepm from age to agelin. 
                   6032:      Look at hpijx to understand the reason of that which relies in memory size
                   6033:      and note for a fixed period like estepm months */
                   6034:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   6035:      survival function given by stepm (the optimization length). Unfortunately it
                   6036:      means that if the survival funtion is printed only each two years of age and if
                   6037:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6038:      results. So we changed our mind and took the option of the best precision.
                   6039:   */
                   6040:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6041: 
                   6042:   /* If stepm=6 months */
                   6043:   /* nhstepm age range expressed in number of stepm */
                   6044:   agelim=AGESUP;
                   6045:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   6046:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   6047:   /* if (stepm >= YEARM) hstepm=1;*/
                   6048:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6049:   
                   6050:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6051:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6052:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   6053:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   6054:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   6055:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   6056: 
                   6057:   for (age=bage; age<=fage; age ++){ 
                   6058:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   6059:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   6060:     /* if (stepm >= YEARM) hstepm=1;*/
                   6061:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  6062:                
1.126     brouard  6063:     /* If stepm=6 months */
                   6064:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   6065:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   6066:     
                   6067:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  6068:                
1.126     brouard  6069:     /* Computing  Variances of health expectancies */
                   6070:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   6071:        decrease memory allocation */
                   6072:     for(theta=1; theta <=npar; theta++){
                   6073:       for(i=1; i<=npar; i++){ 
1.222     brouard  6074:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6075:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  6076:       }
1.235     brouard  6077:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   6078:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  6079:                        
1.126     brouard  6080:       for(j=1; j<= nlstate; j++){
1.222     brouard  6081:        for(i=1; i<=nlstate; i++){
                   6082:          for(h=0; h<=nhstepm-1; h++){
                   6083:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   6084:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   6085:          }
                   6086:        }
1.126     brouard  6087:       }
1.218     brouard  6088:                        
1.126     brouard  6089:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  6090:        for(h=0; h<=nhstepm-1; h++){
                   6091:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   6092:        }
1.126     brouard  6093:     }/* End theta */
                   6094:     
                   6095:     
                   6096:     for(h=0; h<=nhstepm-1; h++)
                   6097:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  6098:        for(theta=1; theta <=npar; theta++)
                   6099:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  6100:     
1.218     brouard  6101:                
1.222     brouard  6102:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  6103:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  6104:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  6105:                
1.222     brouard  6106:     printf("%d|",(int)age);fflush(stdout);
                   6107:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   6108:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  6109:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  6110:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   6111:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   6112:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   6113:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   6114:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  6115:       }
                   6116:     }
1.319   ! brouard  6117:     if((int)age ==50){
        !          6118:       printf(" age=%d cij=%d nres=%d varhe[%d][%d]=%f ",(int)age, cij, nres, 1,2,varhe[1][2]);
        !          6119:     }
1.126     brouard  6120:     /* Computing expectancies */
1.235     brouard  6121:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  6122:     for(i=1; i<=nlstate;i++)
                   6123:       for(j=1; j<=nlstate;j++)
1.222     brouard  6124:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   6125:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  6126:                                        
1.222     brouard  6127:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  6128:                                        
1.222     brouard  6129:        }
1.269     brouard  6130: 
                   6131:     /* Standard deviation of expectancies ij */                
1.126     brouard  6132:     fprintf(ficresstdeij,"%3.0f",age );
                   6133:     for(i=1; i<=nlstate;i++){
                   6134:       eip=0.;
                   6135:       vip=0.;
                   6136:       for(j=1; j<=nlstate;j++){
1.222     brouard  6137:        eip += eij[i][j][(int)age];
                   6138:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   6139:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   6140:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  6141:       }
                   6142:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   6143:     }
                   6144:     fprintf(ficresstdeij,"\n");
1.218     brouard  6145:                
1.269     brouard  6146:     /* Variance of expectancies ij */          
1.126     brouard  6147:     fprintf(ficrescveij,"%3.0f",age );
                   6148:     for(i=1; i<=nlstate;i++)
                   6149:       for(j=1; j<=nlstate;j++){
1.222     brouard  6150:        cptj= (j-1)*nlstate+i;
                   6151:        for(i2=1; i2<=nlstate;i2++)
                   6152:          for(j2=1; j2<=nlstate;j2++){
                   6153:            cptj2= (j2-1)*nlstate+i2;
                   6154:            if(cptj2 <= cptj)
                   6155:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   6156:          }
1.126     brouard  6157:       }
                   6158:     fprintf(ficrescveij,"\n");
1.218     brouard  6159:                
1.126     brouard  6160:   }
                   6161:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   6162:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   6163:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   6164:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   6165:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6166:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6167:   printf("\n");
                   6168:   fprintf(ficlog,"\n");
1.218     brouard  6169:        
1.126     brouard  6170:   free_vector(xm,1,npar);
                   6171:   free_vector(xp,1,npar);
                   6172:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   6173:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   6174:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   6175: }
1.218     brouard  6176:  
1.126     brouard  6177: /************ Variance ******************/
1.235     brouard  6178:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  6179:  {
1.279     brouard  6180:    /** Variance of health expectancies 
                   6181:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   6182:     * double **newm;
                   6183:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   6184:     */
1.218     brouard  6185:   
                   6186:    /* int movingaverage(); */
                   6187:    double **dnewm,**doldm;
                   6188:    double **dnewmp,**doldmp;
                   6189:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  6190:    int first=0;
1.218     brouard  6191:    int k;
                   6192:    double *xp;
1.279     brouard  6193:    double **gp, **gm;  /**< for var eij */
                   6194:    double ***gradg, ***trgradg; /**< for var eij */
                   6195:    double **gradgp, **trgradgp; /**< for var p point j */
                   6196:    double *gpp, *gmp; /**< for var p point j */
                   6197:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  6198:    double ***p3mat;
                   6199:    double age,agelim, hf;
                   6200:    /* double ***mobaverage; */
                   6201:    int theta;
                   6202:    char digit[4];
                   6203:    char digitp[25];
                   6204: 
                   6205:    char fileresprobmorprev[FILENAMELENGTH];
                   6206: 
                   6207:    if(popbased==1){
                   6208:      if(mobilav!=0)
                   6209:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   6210:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   6211:    }
                   6212:    else 
                   6213:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  6214: 
1.218     brouard  6215:    /* if (mobilav!=0) { */
                   6216:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6217:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   6218:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   6219:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   6220:    /*   } */
                   6221:    /* } */
                   6222: 
                   6223:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   6224:    sprintf(digit,"%-d",ij);
                   6225:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   6226:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   6227:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   6228:    strcat(fileresprobmorprev,fileresu);
                   6229:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   6230:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   6231:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   6232:    }
                   6233:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6234:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6235:    pstamp(ficresprobmorprev);
                   6236:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  6237:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   6238:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   6239:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   6240:    }
                   6241:    for(j=1;j<=cptcoveff;j++) 
                   6242:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   6243:    fprintf(ficresprobmorprev,"\n");
                   6244: 
1.218     brouard  6245:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   6246:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6247:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   6248:      for(i=1; i<=nlstate;i++)
                   6249:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   6250:    }  
                   6251:    fprintf(ficresprobmorprev,"\n");
                   6252:   
                   6253:    fprintf(ficgp,"\n# Routine varevsij");
                   6254:    fprintf(ficgp,"\nunset title \n");
                   6255:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   6256:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   6257:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  6258: 
1.218     brouard  6259:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6260:    pstamp(ficresvij);
                   6261:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   6262:    if(popbased==1)
                   6263:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   6264:    else
                   6265:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   6266:    fprintf(ficresvij,"# Age");
                   6267:    for(i=1; i<=nlstate;i++)
                   6268:      for(j=1; j<=nlstate;j++)
                   6269:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   6270:    fprintf(ficresvij,"\n");
                   6271: 
                   6272:    xp=vector(1,npar);
                   6273:    dnewm=matrix(1,nlstate,1,npar);
                   6274:    doldm=matrix(1,nlstate,1,nlstate);
                   6275:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   6276:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6277: 
                   6278:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   6279:    gpp=vector(nlstate+1,nlstate+ndeath);
                   6280:    gmp=vector(nlstate+1,nlstate+ndeath);
                   6281:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  6282:   
1.218     brouard  6283:    if(estepm < stepm){
                   6284:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   6285:    }
                   6286:    else  hstepm=estepm;   
                   6287:    /* For example we decided to compute the life expectancy with the smallest unit */
                   6288:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6289:       nhstepm is the number of hstepm from age to agelim 
                   6290:       nstepm is the number of stepm from age to agelim. 
                   6291:       Look at function hpijx to understand why because of memory size limitations, 
                   6292:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   6293:       survival function given by stepm (the optimization length). Unfortunately it
                   6294:       means that if the survival funtion is printed every two years of age and if
                   6295:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6296:       results. So we changed our mind and took the option of the best precision.
                   6297:    */
                   6298:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6299:    agelim = AGESUP;
                   6300:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6301:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6302:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6303:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6304:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   6305:      gp=matrix(0,nhstepm,1,nlstate);
                   6306:      gm=matrix(0,nhstepm,1,nlstate);
                   6307:                
                   6308:                
                   6309:      for(theta=1; theta <=npar; theta++){
                   6310:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   6311:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6312:        }
1.279     brouard  6313:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   6314:        * returns into prlim .
1.288     brouard  6315:        */
1.242     brouard  6316:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  6317: 
                   6318:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  6319:        if (popbased==1) {
                   6320:         if(mobilav ==0){
                   6321:           for(i=1; i<=nlstate;i++)
                   6322:             prlim[i][i]=probs[(int)age][i][ij];
                   6323:         }else{ /* mobilav */ 
                   6324:           for(i=1; i<=nlstate;i++)
                   6325:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6326:         }
                   6327:        }
1.295     brouard  6328:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}x\f$ at horizon h.
1.279     brouard  6329:        */                      
                   6330:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
1.292     brouard  6331:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}x\f$, which are the probability
1.279     brouard  6332:        * at horizon h in state j including mortality.
                   6333:        */
1.218     brouard  6334:        for(j=1; j<= nlstate; j++){
                   6335:         for(h=0; h<=nhstepm; h++){
                   6336:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6337:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6338:         }
                   6339:        }
1.279     brouard  6340:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6341:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6342:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6343:        */
                   6344:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6345:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6346:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6347:        }
                   6348:        
                   6349:        /* Again with minus shift */
1.218     brouard  6350:                        
                   6351:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6352:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6353: 
1.242     brouard  6354:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6355:                        
                   6356:        if (popbased==1) {
                   6357:         if(mobilav ==0){
                   6358:           for(i=1; i<=nlstate;i++)
                   6359:             prlim[i][i]=probs[(int)age][i][ij];
                   6360:         }else{ /* mobilav */ 
                   6361:           for(i=1; i<=nlstate;i++)
                   6362:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6363:         }
                   6364:        }
                   6365:                        
1.235     brouard  6366:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6367:                        
                   6368:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6369:         for(h=0; h<=nhstepm; h++){
                   6370:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6371:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6372:         }
                   6373:        }
                   6374:        /* This for computing probability of death (h=1 means
                   6375:          computed over hstepm matrices product = hstepm*stepm months) 
                   6376:          as a weighted average of prlim.
                   6377:        */
                   6378:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6379:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6380:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6381:        }    
1.279     brouard  6382:        /* end shifting computations */
                   6383: 
                   6384:        /**< Computing gradient matrix at horizon h 
                   6385:        */
1.218     brouard  6386:        for(j=1; j<= nlstate; j++) /* vareij */
                   6387:         for(h=0; h<=nhstepm; h++){
                   6388:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6389:         }
1.279     brouard  6390:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6391:        */
                   6392:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6393:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6394:        }
                   6395:                        
                   6396:      } /* End theta */
1.279     brouard  6397:      
                   6398:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6399:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6400:                
                   6401:      for(h=0; h<=nhstepm; h++) /* veij */
                   6402:        for(j=1; j<=nlstate;j++)
                   6403:         for(theta=1; theta <=npar; theta++)
                   6404:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6405:                
                   6406:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6407:        for(theta=1; theta <=npar; theta++)
                   6408:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6409:      /**< as well as its transposed matrix 
                   6410:       */               
1.218     brouard  6411:                
                   6412:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6413:      for(i=1;i<=nlstate;i++)
                   6414:        for(j=1;j<=nlstate;j++)
                   6415:         vareij[i][j][(int)age] =0.;
1.279     brouard  6416: 
                   6417:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6418:       * and k (nhstepm) formula 15 of article
                   6419:       * Lievre-Brouard-Heathcote
                   6420:       */
                   6421:      
1.218     brouard  6422:      for(h=0;h<=nhstepm;h++){
                   6423:        for(k=0;k<=nhstepm;k++){
                   6424:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6425:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6426:         for(i=1;i<=nlstate;i++)
                   6427:           for(j=1;j<=nlstate;j++)
                   6428:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6429:        }
                   6430:      }
                   6431:                
1.279     brouard  6432:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6433:       * p.j overall mortality formula 49 but computed directly because
                   6434:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6435:       * wix is independent of theta.
                   6436:       */
1.218     brouard  6437:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6438:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6439:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6440:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6441:         varppt[j][i]=doldmp[j][i];
                   6442:      /* end ppptj */
                   6443:      /*  x centered again */
                   6444:                
1.242     brouard  6445:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6446:                
                   6447:      if (popbased==1) {
                   6448:        if(mobilav ==0){
                   6449:         for(i=1; i<=nlstate;i++)
                   6450:           prlim[i][i]=probs[(int)age][i][ij];
                   6451:        }else{ /* mobilav */ 
                   6452:         for(i=1; i<=nlstate;i++)
                   6453:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6454:        }
                   6455:      }
                   6456:                
                   6457:      /* This for computing probability of death (h=1 means
                   6458:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6459:        as a weighted average of prlim.
                   6460:      */
1.235     brouard  6461:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6462:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6463:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6464:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6465:      }    
                   6466:      /* end probability of death */
                   6467:                
                   6468:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6469:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6470:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6471:        for(i=1; i<=nlstate;i++){
                   6472:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6473:        }
                   6474:      } 
                   6475:      fprintf(ficresprobmorprev,"\n");
                   6476:                
                   6477:      fprintf(ficresvij,"%.0f ",age );
                   6478:      for(i=1; i<=nlstate;i++)
                   6479:        for(j=1; j<=nlstate;j++){
                   6480:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6481:        }
                   6482:      fprintf(ficresvij,"\n");
                   6483:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6484:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6485:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6486:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6487:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6488:    } /* End age */
                   6489:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6490:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6491:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6492:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6493:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6494:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6495:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6496:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6497:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6498:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6499:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6500:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6501:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6502:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6503:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6504:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6505:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6506:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6507:     */
1.218     brouard  6508:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6509:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6510: 
1.218     brouard  6511:    free_vector(xp,1,npar);
                   6512:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6513:    free_matrix(dnewm,1,nlstate,1,npar);
                   6514:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6515:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6516:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6517:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6518:    fclose(ficresprobmorprev);
                   6519:    fflush(ficgp);
                   6520:    fflush(fichtm); 
                   6521:  }  /* end varevsij */
1.126     brouard  6522: 
                   6523: /************ Variance of prevlim ******************/
1.269     brouard  6524:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6525: {
1.205     brouard  6526:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6527:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6528: 
1.268     brouard  6529:   double **dnewmpar,**doldm;
1.126     brouard  6530:   int i, j, nhstepm, hstepm;
                   6531:   double *xp;
                   6532:   double *gp, *gm;
                   6533:   double **gradg, **trgradg;
1.208     brouard  6534:   double **mgm, **mgp;
1.126     brouard  6535:   double age,agelim;
                   6536:   int theta;
                   6537:   
                   6538:   pstamp(ficresvpl);
1.288     brouard  6539:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6540:   fprintf(ficresvpl,"# Age ");
                   6541:   if(nresult >=1)
                   6542:     fprintf(ficresvpl," Result# ");
1.126     brouard  6543:   for(i=1; i<=nlstate;i++)
                   6544:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6545:   fprintf(ficresvpl,"\n");
                   6546: 
                   6547:   xp=vector(1,npar);
1.268     brouard  6548:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6549:   doldm=matrix(1,nlstate,1,nlstate);
                   6550:   
                   6551:   hstepm=1*YEARM; /* Every year of age */
                   6552:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6553:   agelim = AGESUP;
                   6554:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6555:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6556:     if (stepm >= YEARM) hstepm=1;
                   6557:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6558:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6559:     mgp=matrix(1,npar,1,nlstate);
                   6560:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6561:     gp=vector(1,nlstate);
                   6562:     gm=vector(1,nlstate);
                   6563: 
                   6564:     for(theta=1; theta <=npar; theta++){
                   6565:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6566:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6567:       }
1.288     brouard  6568:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6569:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6570:       /* else */
                   6571:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6572:       for(i=1;i<=nlstate;i++){
1.126     brouard  6573:        gp[i] = prlim[i][i];
1.208     brouard  6574:        mgp[theta][i] = prlim[i][i];
                   6575:       }
1.126     brouard  6576:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6577:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6578:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6579:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6580:       /* else */
                   6581:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6582:       for(i=1;i<=nlstate;i++){
1.126     brouard  6583:        gm[i] = prlim[i][i];
1.208     brouard  6584:        mgm[theta][i] = prlim[i][i];
                   6585:       }
1.126     brouard  6586:       for(i=1;i<=nlstate;i++)
                   6587:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6588:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6589:     } /* End theta */
                   6590: 
                   6591:     trgradg =matrix(1,nlstate,1,npar);
                   6592: 
                   6593:     for(j=1; j<=nlstate;j++)
                   6594:       for(theta=1; theta <=npar; theta++)
                   6595:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6596:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6597:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6598:     /*   for(j=1; j<=nlstate;j++){ */
                   6599:     /*         printf(" %d ",j); */
                   6600:     /*         for(theta=1; theta <=npar; theta++) */
                   6601:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6602:     /*         printf("\n "); */
                   6603:     /*   } */
                   6604:     /* } */
                   6605:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6606:     /*   printf("\n gradg %d ",(int)age); */
                   6607:     /*   for(j=1; j<=nlstate;j++){ */
                   6608:     /*         printf("%d ",j); */
                   6609:     /*         for(theta=1; theta <=npar; theta++) */
                   6610:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6611:     /*         printf("\n "); */
                   6612:     /*   } */
                   6613:     /* } */
1.126     brouard  6614: 
                   6615:     for(i=1;i<=nlstate;i++)
                   6616:       varpl[i][(int)age] =0.;
1.209     brouard  6617:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6618:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6619:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6620:     }else{
1.268     brouard  6621:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6622:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6623:     }
1.126     brouard  6624:     for(i=1;i<=nlstate;i++)
                   6625:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6626: 
                   6627:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6628:     if(nresult >=1)
                   6629:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6630:     for(i=1; i<=nlstate;i++){
1.126     brouard  6631:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6632:       /* for(j=1;j<=nlstate;j++) */
                   6633:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6634:     }
1.126     brouard  6635:     fprintf(ficresvpl,"\n");
                   6636:     free_vector(gp,1,nlstate);
                   6637:     free_vector(gm,1,nlstate);
1.208     brouard  6638:     free_matrix(mgm,1,npar,1,nlstate);
                   6639:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6640:     free_matrix(gradg,1,npar,1,nlstate);
                   6641:     free_matrix(trgradg,1,nlstate,1,npar);
                   6642:   } /* End age */
                   6643: 
                   6644:   free_vector(xp,1,npar);
                   6645:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6646:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6647: 
                   6648: }
                   6649: 
                   6650: 
                   6651: /************ Variance of backprevalence limit ******************/
1.269     brouard  6652:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6653: {
                   6654:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6655:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6656: 
                   6657:   double **dnewmpar,**doldm;
                   6658:   int i, j, nhstepm, hstepm;
                   6659:   double *xp;
                   6660:   double *gp, *gm;
                   6661:   double **gradg, **trgradg;
                   6662:   double **mgm, **mgp;
                   6663:   double age,agelim;
                   6664:   int theta;
                   6665:   
                   6666:   pstamp(ficresvbl);
                   6667:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6668:   fprintf(ficresvbl,"# Age ");
                   6669:   if(nresult >=1)
                   6670:     fprintf(ficresvbl," Result# ");
                   6671:   for(i=1; i<=nlstate;i++)
                   6672:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6673:   fprintf(ficresvbl,"\n");
                   6674: 
                   6675:   xp=vector(1,npar);
                   6676:   dnewmpar=matrix(1,nlstate,1,npar);
                   6677:   doldm=matrix(1,nlstate,1,nlstate);
                   6678:   
                   6679:   hstepm=1*YEARM; /* Every year of age */
                   6680:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6681:   agelim = AGEINF;
                   6682:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6683:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6684:     if (stepm >= YEARM) hstepm=1;
                   6685:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6686:     gradg=matrix(1,npar,1,nlstate);
                   6687:     mgp=matrix(1,npar,1,nlstate);
                   6688:     mgm=matrix(1,npar,1,nlstate);
                   6689:     gp=vector(1,nlstate);
                   6690:     gm=vector(1,nlstate);
                   6691: 
                   6692:     for(theta=1; theta <=npar; theta++){
                   6693:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6694:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6695:       }
                   6696:       if(mobilavproj > 0 )
                   6697:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6698:       else
                   6699:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6700:       for(i=1;i<=nlstate;i++){
                   6701:        gp[i] = bprlim[i][i];
                   6702:        mgp[theta][i] = bprlim[i][i];
                   6703:       }
                   6704:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6705:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6706:        if(mobilavproj > 0 )
                   6707:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6708:        else
                   6709:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6710:       for(i=1;i<=nlstate;i++){
                   6711:        gm[i] = bprlim[i][i];
                   6712:        mgm[theta][i] = bprlim[i][i];
                   6713:       }
                   6714:       for(i=1;i<=nlstate;i++)
                   6715:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6716:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6717:     } /* End theta */
                   6718: 
                   6719:     trgradg =matrix(1,nlstate,1,npar);
                   6720: 
                   6721:     for(j=1; j<=nlstate;j++)
                   6722:       for(theta=1; theta <=npar; theta++)
                   6723:        trgradg[j][theta]=gradg[theta][j];
                   6724:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6725:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6726:     /*   for(j=1; j<=nlstate;j++){ */
                   6727:     /*         printf(" %d ",j); */
                   6728:     /*         for(theta=1; theta <=npar; theta++) */
                   6729:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6730:     /*         printf("\n "); */
                   6731:     /*   } */
                   6732:     /* } */
                   6733:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6734:     /*   printf("\n gradg %d ",(int)age); */
                   6735:     /*   for(j=1; j<=nlstate;j++){ */
                   6736:     /*         printf("%d ",j); */
                   6737:     /*         for(theta=1; theta <=npar; theta++) */
                   6738:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6739:     /*         printf("\n "); */
                   6740:     /*   } */
                   6741:     /* } */
                   6742: 
                   6743:     for(i=1;i<=nlstate;i++)
                   6744:       varbpl[i][(int)age] =0.;
                   6745:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6746:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6747:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6748:     }else{
                   6749:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6750:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6751:     }
                   6752:     for(i=1;i<=nlstate;i++)
                   6753:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6754: 
                   6755:     fprintf(ficresvbl,"%.0f ",age );
                   6756:     if(nresult >=1)
                   6757:       fprintf(ficresvbl,"%d ",nres );
                   6758:     for(i=1; i<=nlstate;i++)
                   6759:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6760:     fprintf(ficresvbl,"\n");
                   6761:     free_vector(gp,1,nlstate);
                   6762:     free_vector(gm,1,nlstate);
                   6763:     free_matrix(mgm,1,npar,1,nlstate);
                   6764:     free_matrix(mgp,1,npar,1,nlstate);
                   6765:     free_matrix(gradg,1,npar,1,nlstate);
                   6766:     free_matrix(trgradg,1,nlstate,1,npar);
                   6767:   } /* End age */
                   6768: 
                   6769:   free_vector(xp,1,npar);
                   6770:   free_matrix(doldm,1,nlstate,1,npar);
                   6771:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6772: 
                   6773: }
                   6774: 
                   6775: /************ Variance of one-step probabilities  ******************/
                   6776: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6777:  {
                   6778:    int i, j=0,  k1, l1, tj;
                   6779:    int k2, l2, j1,  z1;
                   6780:    int k=0, l;
                   6781:    int first=1, first1, first2;
                   6782:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6783:    double **dnewm,**doldm;
                   6784:    double *xp;
                   6785:    double *gp, *gm;
                   6786:    double **gradg, **trgradg;
                   6787:    double **mu;
                   6788:    double age, cov[NCOVMAX+1];
                   6789:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6790:    int theta;
                   6791:    char fileresprob[FILENAMELENGTH];
                   6792:    char fileresprobcov[FILENAMELENGTH];
                   6793:    char fileresprobcor[FILENAMELENGTH];
                   6794:    double ***varpij;
                   6795: 
                   6796:    strcpy(fileresprob,"PROB_"); 
                   6797:    strcat(fileresprob,fileres);
                   6798:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6799:      printf("Problem with resultfile: %s\n", fileresprob);
                   6800:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6801:    }
                   6802:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6803:    strcat(fileresprobcov,fileresu);
                   6804:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6805:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6806:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6807:    }
                   6808:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6809:    strcat(fileresprobcor,fileresu);
                   6810:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6811:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6812:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6813:    }
                   6814:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6815:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6816:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6817:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6818:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6819:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6820:    pstamp(ficresprob);
                   6821:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6822:    fprintf(ficresprob,"# Age");
                   6823:    pstamp(ficresprobcov);
                   6824:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6825:    fprintf(ficresprobcov,"# Age");
                   6826:    pstamp(ficresprobcor);
                   6827:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6828:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6829: 
                   6830: 
1.222     brouard  6831:    for(i=1; i<=nlstate;i++)
                   6832:      for(j=1; j<=(nlstate+ndeath);j++){
                   6833:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6834:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6835:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6836:      }  
                   6837:    /* fprintf(ficresprob,"\n");
                   6838:       fprintf(ficresprobcov,"\n");
                   6839:       fprintf(ficresprobcor,"\n");
                   6840:    */
                   6841:    xp=vector(1,npar);
                   6842:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6843:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6844:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6845:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6846:    first=1;
                   6847:    fprintf(ficgp,"\n# Routine varprob");
                   6848:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6849:    fprintf(fichtm,"\n");
                   6850: 
1.288     brouard  6851:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6852:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6853:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6854: and drawn. It helps understanding how is the covariance between two incidences.\
                   6855:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6856:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6857: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6858: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6859: standard deviations wide on each axis. <br>\
                   6860:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6861:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6862: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6863: 
1.222     brouard  6864:    cov[1]=1;
                   6865:    /* tj=cptcoveff; */
1.225     brouard  6866:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6867:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6868:    j1=0;
1.224     brouard  6869:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6870:      if  (cptcovn>0) {
                   6871:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6872:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6873:        fprintf(ficresprob, "**********\n#\n");
                   6874:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6875:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6876:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6877:                        
1.222     brouard  6878:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6879:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6880:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6881:                        
                   6882:                        
1.222     brouard  6883:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.319   ! brouard  6884:        /* for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); */
        !          6885:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtmcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6886:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6887:                        
1.222     brouard  6888:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6889:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6890:        fprintf(ficresprobcor, "**********\n#");    
                   6891:        if(invalidvarcomb[j1]){
                   6892:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6893:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6894:         continue;
                   6895:        }
                   6896:      }
                   6897:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6898:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6899:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6900:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6901:      for (age=bage; age<=fage; age ++){ 
                   6902:        cov[2]=age;
                   6903:        if(nagesqr==1)
                   6904:         cov[3]= age*age;
                   6905:        for (k=1; k<=cptcovn;k++) {
                   6906:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6907:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6908:                                                                    * 1  1 1 1 1
                   6909:                                                                    * 2  2 1 1 1
                   6910:                                                                    * 3  1 2 1 1
                   6911:                                                                    */
                   6912:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6913:        }
1.319   ! brouard  6914:        /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1, Tage[1]=2 */
        !          6915:        /* ) p nbcode[Tvar[Tage[k]]][(1 & (ij-1) >> (k-1))+1] */
        !          6916:        /*for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
        !          6917:        for (k=1; k<=cptcovage;k++)
        !          6918:         cov[2+Tage[k]+nagesqr]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.222     brouard  6919:        for (k=1; k<=cptcovprod;k++)
                   6920:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6921:                        
                   6922:                        
1.222     brouard  6923:        for(theta=1; theta <=npar; theta++){
                   6924:         for(i=1; i<=npar; i++)
                   6925:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6926:                                
1.222     brouard  6927:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6928:                                
1.222     brouard  6929:         k=0;
                   6930:         for(i=1; i<= (nlstate); i++){
                   6931:           for(j=1; j<=(nlstate+ndeath);j++){
                   6932:             k=k+1;
                   6933:             gp[k]=pmmij[i][j];
                   6934:           }
                   6935:         }
1.220     brouard  6936:                                
1.222     brouard  6937:         for(i=1; i<=npar; i++)
                   6938:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6939:                                
1.222     brouard  6940:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6941:         k=0;
                   6942:         for(i=1; i<=(nlstate); i++){
                   6943:           for(j=1; j<=(nlstate+ndeath);j++){
                   6944:             k=k+1;
                   6945:             gm[k]=pmmij[i][j];
                   6946:           }
                   6947:         }
1.220     brouard  6948:                                
1.222     brouard  6949:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6950:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6951:        }
1.126     brouard  6952: 
1.222     brouard  6953:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6954:         for(theta=1; theta <=npar; theta++)
                   6955:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6956:                        
1.222     brouard  6957:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6958:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6959:                        
1.222     brouard  6960:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6961:                        
1.222     brouard  6962:        k=0;
                   6963:        for(i=1; i<=(nlstate); i++){
                   6964:         for(j=1; j<=(nlstate+ndeath);j++){
                   6965:           k=k+1;
                   6966:           mu[k][(int) age]=pmmij[i][j];
                   6967:         }
                   6968:        }
                   6969:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6970:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6971:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6972:                        
1.222     brouard  6973:        /*printf("\n%d ",(int)age);
                   6974:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6975:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6976:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6977:         }*/
1.220     brouard  6978:                        
1.222     brouard  6979:        fprintf(ficresprob,"\n%d ",(int)age);
                   6980:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6981:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6982:                        
1.222     brouard  6983:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6984:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6985:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6986:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6987:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6988:        }
                   6989:        i=0;
                   6990:        for (k=1; k<=(nlstate);k++){
                   6991:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6992:           i++;
                   6993:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6994:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6995:           for (j=1; j<=i;j++){
                   6996:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6997:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6998:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6999:           }
                   7000:         }
                   7001:        }/* end of loop for state */
                   7002:      } /* end of loop for age */
                   7003:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   7004:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   7005:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   7006:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   7007:     
                   7008:      /* Confidence intervalle of pij  */
                   7009:      /*
                   7010:        fprintf(ficgp,"\nunset parametric;unset label");
                   7011:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   7012:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   7013:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   7014:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   7015:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   7016:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   7017:      */
                   7018:                
                   7019:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   7020:      first1=1;first2=2;
                   7021:      for (k2=1; k2<=(nlstate);k2++){
                   7022:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   7023:         if(l2==k2) continue;
                   7024:         j=(k2-1)*(nlstate+ndeath)+l2;
                   7025:         for (k1=1; k1<=(nlstate);k1++){
                   7026:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   7027:             if(l1==k1) continue;
                   7028:             i=(k1-1)*(nlstate+ndeath)+l1;
                   7029:             if(i<=j) continue;
                   7030:             for (age=bage; age<=fage; age ++){ 
                   7031:               if ((int)age %5==0){
                   7032:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   7033:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   7034:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   7035:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   7036:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   7037:                 c12=cv12/sqrt(v1*v2);
                   7038:                 /* Computing eigen value of matrix of covariance */
                   7039:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   7040:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   7041:                 if ((lc2 <0) || (lc1 <0) ){
                   7042:                   if(first2==1){
                   7043:                     first1=0;
                   7044:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   7045:                   }
                   7046:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   7047:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   7048:                   /* lc2=fabs(lc2); */
                   7049:                 }
1.220     brouard  7050:                                                                
1.222     brouard  7051:                 /* Eigen vectors */
1.280     brouard  7052:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   7053:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   7054:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   7055:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   7056:                 }else
                   7057:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  7058:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   7059:                 v21=(lc1-v1)/cv12*v11;
                   7060:                 v12=-v21;
                   7061:                 v22=v11;
                   7062:                 tnalp=v21/v11;
                   7063:                 if(first1==1){
                   7064:                   first1=0;
                   7065:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   7066:                 }
                   7067:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   7068:                 /*printf(fignu*/
                   7069:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   7070:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   7071:                 if(first==1){
                   7072:                   first=0;
                   7073:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   7074:                   fprintf(ficgp,"\nset parametric;unset label");
                   7075:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   7076:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  7077:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  7078:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  7079: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  7080:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   7081:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7082:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7083:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   7084:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7085:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   7086:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   7087:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  7088:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   7089:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  7090:                 }else{
                   7091:                   first=0;
                   7092:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   7093:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   7094:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   7095:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  7096:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   7097:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  7098:                 }/* if first */
                   7099:               } /* age mod 5 */
                   7100:             } /* end loop age */
                   7101:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7102:             first=1;
                   7103:           } /*l12 */
                   7104:         } /* k12 */
                   7105:        } /*l1 */
                   7106:      }/* k1 */
                   7107:    }  /* loop on combination of covariates j1 */
                   7108:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   7109:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   7110:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   7111:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   7112:    free_vector(xp,1,npar);
                   7113:    fclose(ficresprob);
                   7114:    fclose(ficresprobcov);
                   7115:    fclose(ficresprobcor);
                   7116:    fflush(ficgp);
                   7117:    fflush(fichtmcov);
                   7118:  }
1.126     brouard  7119: 
                   7120: 
                   7121: /******************* Printing html file ***********/
1.201     brouard  7122: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  7123:                  int lastpass, int stepm, int weightopt, char model[],\
                   7124:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.296     brouard  7125:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int prevbcast, int estepm , \
                   7126:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateprojd, double dateback1, \
                   7127:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateprojf, double dateback2){
1.237     brouard  7128:   int jj1, k1, i1, cpt, k4, nres;
1.319   ! brouard  7129:   /* In fact some results are already printed in fichtm which is open */
1.126     brouard  7130:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   7131:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   7132: </ul>");
1.319   ! brouard  7133: /*    fprintf(fichtm,"<ul><li> model=1+age+%s\n \ */
        !          7134: /* </ul>", model); */
1.214     brouard  7135:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   7136:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   7137:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   7138:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  7139:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   7140:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  7141:    fprintf(fichtm,"\
                   7142:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  7143:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  7144:    fprintf(fichtm,"\
1.217     brouard  7145:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   7146:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   7147:    fprintf(fichtm,"\
1.288     brouard  7148:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  7149:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  7150:    fprintf(fichtm,"\
1.288     brouard  7151:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  7152:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   7153:    fprintf(fichtm,"\
1.211     brouard  7154:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  7155:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  7156:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  7157:    if(prevfcast==1){
                   7158:      fprintf(fichtm,"\
                   7159:  - Prevalence projections by age and states:                           \
1.201     brouard  7160:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  7161:    }
1.126     brouard  7162: 
                   7163: 
1.225     brouard  7164:    m=pow(2,cptcoveff);
1.222     brouard  7165:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7166: 
1.317     brouard  7167:    fprintf(fichtm," \n<ul><li><b>Graphs (first order)</b></li><p>");
1.264     brouard  7168: 
                   7169:    jj1=0;
                   7170: 
                   7171:    fprintf(fichtm," \n<ul>");
                   7172:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7173:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   7174:      if(m != 1 && TKresult[nres]!= k1)
                   7175:        continue;
                   7176:      jj1++;
                   7177:      if (cptcovn > 0) {
                   7178:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   7179:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7180:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7181:        }
                   7182:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7183:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7184:        }
                   7185:        fprintf(fichtm,"\">");
                   7186:        
                   7187:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   7188:        fprintf(fichtm,"************ Results for covariates");
                   7189:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7190:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7191:        }
                   7192:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7193:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7194:        }
                   7195:        if(invalidvarcomb[k1]){
                   7196:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   7197:         continue;
                   7198:        }
                   7199:        fprintf(fichtm,"</a></li>");
                   7200:      } /* cptcovn >0 */
                   7201:    }
1.317     brouard  7202:    fprintf(fichtm," \n</ul>");
1.264     brouard  7203: 
1.222     brouard  7204:    jj1=0;
1.237     brouard  7205: 
                   7206:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  7207:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  7208:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7209:        continue;
1.220     brouard  7210: 
1.222     brouard  7211:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7212:      jj1++;
                   7213:      if (cptcovn > 0) {
1.264     brouard  7214:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   7215:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7216:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7217:        }
                   7218:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7219:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7220:        }
                   7221:        fprintf(fichtm,"\"</a>");
                   7222:  
1.222     brouard  7223:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7224:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  7225:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7226:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   7227:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7228:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  7229:        }
1.237     brouard  7230:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7231:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7232:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   7233:       }
                   7234:        
1.230     brouard  7235:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  7236:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   7237:        if(invalidvarcomb[k1]){
                   7238:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   7239:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   7240:         continue;
                   7241:        }
                   7242:      }
                   7243:      /* aij, bij */
1.259     brouard  7244:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  7245: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  7246:      /* Pij */
1.241     brouard  7247:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   7248: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  7249:      /* Quasi-incidences */
                   7250:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  7251:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  7252:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  7253: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   7254: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  7255:      /* Survival functions (period) in state j */
                   7256:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7257:        fprintf(fichtm,"<br>\n- Survival functions in state %d. And probability to be observed in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7258: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  7259:      }
                   7260:      /* State specific survival functions (period) */
                   7261:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7262:        fprintf(fichtm,"<br>\n- Survival functions in state %d and in any other live state (total).\
                   7263:  And probability to be observed in various states (up to %d) being in state %d at different ages.      \
1.283     brouard  7264:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  7265:      }
1.288     brouard  7266:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  7267:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7268:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7269: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  7270:      }
1.296     brouard  7271:      if(prevbcast==1){
1.288     brouard  7272:        /* Backward prevalence in each health state */
1.222     brouard  7273:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7274:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7275: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  7276:        }
1.217     brouard  7277:      }
1.222     brouard  7278:      if(prevfcast==1){
1.288     brouard  7279:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  7280:        for(cpt=1; cpt<=nlstate;cpt++){
1.314     brouard  7281:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>", dateprev1, dateprev2, mobilavproj, dateprojd, dateprojf, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
                   7282:         fprintf(fichtm," (data from text file  <a href=\"%s.txt\">%s.txt</a>)\n<br>",subdirf2(optionfilefiname,"F_"),subdirf2(optionfilefiname,"F_"));
                   7283:         fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">",
                   7284:                 subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  7285:        }
                   7286:      }
1.296     brouard  7287:      if(prevbcast==1){
1.268     brouard  7288:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   7289:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  7290:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   7291:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   7292:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
1.314     brouard  7293: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7294:         fprintf(fichtm," (data from text file  <a href=\"%s.txt\">%s.txt</a>)\n<br>",subdirf2(optionfilefiname,"FB_"),subdirf2(optionfilefiname,"FB_"));
                   7295:         fprintf(fichtm," <img src=\"%s_%d-%d-%d.svg\">", subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  7296:        }
                   7297:      }
1.220     brouard  7298:         
1.222     brouard  7299:      for(cpt=1; cpt<=nlstate;cpt++) {
1.314     brouard  7300:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
                   7301:        fprintf(fichtm," (data from text file  <a href=\"%s.txt\"> %s.txt</a>)\n<br>",subdirf2(optionfilefiname,"E_"),subdirf2(optionfilefiname,"E_"));
                   7302:        fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">", subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres );
1.222     brouard  7303:      }
                   7304:      /* } /\* end i1 *\/ */
                   7305:    }/* End k1 */
                   7306:    fprintf(fichtm,"</ul>");
1.126     brouard  7307: 
1.222     brouard  7308:    fprintf(fichtm,"\
1.126     brouard  7309: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  7310:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  7311:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  7312: But because parameters are usually highly correlated (a higher incidence of disability \
                   7313: and a higher incidence of recovery can give very close observed transition) it might \
                   7314: be very useful to look not only at linear confidence intervals estimated from the \
                   7315: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   7316: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   7317: covariance matrix of the one-step probabilities. \
                   7318: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  7319: 
1.222     brouard  7320:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   7321:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   7322:    fprintf(fichtm,"\
1.126     brouard  7323:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7324:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  7325: 
1.222     brouard  7326:    fprintf(fichtm,"\
1.126     brouard  7327:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7328:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   7329:    fprintf(fichtm,"\
1.126     brouard  7330:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7331:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7332:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7333:    fprintf(fichtm,"\
1.126     brouard  7334:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7335:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7336:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7337:    fprintf(fichtm,"\
1.288     brouard  7338:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7339:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7340:    fprintf(fichtm,"\
1.128     brouard  7341:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7342:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7343:    fprintf(fichtm,"\
1.288     brouard  7344:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7345:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7346: 
                   7347: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7348: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7349: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7350: /*     <br>",fileres,fileres,fileres,fileres); */
                   7351: /*  else  */
                   7352: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7353:    fflush(fichtm);
1.126     brouard  7354: 
1.225     brouard  7355:    m=pow(2,cptcoveff);
1.222     brouard  7356:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7357: 
1.317     brouard  7358:    fprintf(fichtm," <ul><li><b>Graphs (second order)</b></li><p>");
                   7359: 
                   7360:   jj1=0;
                   7361: 
                   7362:    fprintf(fichtm," \n<ul>");
                   7363:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7364:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   7365:      if(m != 1 && TKresult[nres]!= k1)
                   7366:        continue;
                   7367:      jj1++;
                   7368:      if (cptcovn > 0) {
                   7369:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescovsecond");
                   7370:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7371:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7372:        }
                   7373:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7374:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7375:        }
                   7376:        fprintf(fichtm,"\">");
                   7377:        
                   7378:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   7379:        fprintf(fichtm,"************ Results for covariates");
                   7380:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7381:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7382:        }
                   7383:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7384:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7385:        }
                   7386:        if(invalidvarcomb[k1]){
                   7387:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   7388:         continue;
                   7389:        }
                   7390:        fprintf(fichtm,"</a></li>");
                   7391:      } /* cptcovn >0 */
                   7392:    }
                   7393:    fprintf(fichtm," \n</ul>");
                   7394: 
1.222     brouard  7395:    jj1=0;
1.237     brouard  7396: 
1.241     brouard  7397:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7398:    for(k1=1; k1<=m;k1++){
1.253     brouard  7399:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7400:        continue;
1.222     brouard  7401:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7402:      jj1++;
1.126     brouard  7403:      if (cptcovn > 0) {
1.317     brouard  7404:        fprintf(fichtm,"\n<p><a name=\"rescovsecond");
                   7405:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7406:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7407:        }
                   7408:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7409:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7410:        }
                   7411:        fprintf(fichtm,"\"</a>");
                   7412:        
1.126     brouard  7413:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.317     brouard  7414:        for (cpt=1; cpt<=cptcoveff;cpt++){  /**< cptcoveff number of variables */
1.237     brouard  7415:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
1.317     brouard  7416:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
1.237     brouard  7417:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
1.317     brouard  7418:        }
1.237     brouard  7419:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7420:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7421:       }
                   7422: 
1.126     brouard  7423:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7424: 
1.222     brouard  7425:        if(invalidvarcomb[k1]){
                   7426:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7427:         continue;
                   7428:        }
1.126     brouard  7429:      }
                   7430:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7431:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.314     brouard  7432: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7433:        fprintf(fichtm," (data from text file  <a href=\"%s\">%s</a>)\n <br>",subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
                   7434:        fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">",subdirf2(optionfilefiname,"V_"), cpt,k1,nres);
1.126     brouard  7435:      }
                   7436:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.314     brouard  7437: health expectancies in each live states (1 to %d). If popbased=1 the smooth (due to the model) \
1.128     brouard  7438: true period expectancies (those weighted with period prevalences are also\
                   7439:  drawn in addition to the population based expectancies computed using\
1.314     brouard  7440:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>",nlstate, subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
                   7441:      fprintf(fichtm," (data from text file <a href=\"%s.txt\">%s.txt</a>) \n<br>",subdirf2(optionfilefiname,"T_"),subdirf2(optionfilefiname,"T_"));
                   7442:      fprintf(fichtm,"<img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7443:      /* } /\* end i1 *\/ */
                   7444:    }/* End k1 */
1.241     brouard  7445:   }/* End nres */
1.222     brouard  7446:    fprintf(fichtm,"</ul>");
                   7447:    fflush(fichtm);
1.126     brouard  7448: }
                   7449: 
                   7450: /******************* Gnuplot file **************/
1.296     brouard  7451: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int prevbcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7452: 
                   7453:   char dirfileres[132],optfileres[132];
1.264     brouard  7454:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7455:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7456:   int lv=0, vlv=0, kl=0;
1.130     brouard  7457:   int ng=0;
1.201     brouard  7458:   int vpopbased;
1.223     brouard  7459:   int ioffset; /* variable offset for columns */
1.270     brouard  7460:   int iyearc=1; /* variable column for year of projection  */
                   7461:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7462:   int nres=0; /* Index of resultline */
1.266     brouard  7463:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7464: 
1.126     brouard  7465: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7466: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7467: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7468: /*   } */
                   7469: 
                   7470:   /*#ifdef windows */
                   7471:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7472:   /*#endif */
1.225     brouard  7473:   m=pow(2,cptcoveff);
1.126     brouard  7474: 
1.274     brouard  7475:   /* diagram of the model */
                   7476:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7477:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7478:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7479:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7480: 
                   7481:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7482:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7483:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7484:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7485:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7486:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7487:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7488: 
1.202     brouard  7489:   /* Contribution to likelihood */
                   7490:   /* Plot the probability implied in the likelihood */
1.223     brouard  7491:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7492:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7493:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7494:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7495: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7496:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7497: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7498:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7499:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7500:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7501:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7502:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7503:   for (i=1; i<= nlstate ; i ++) {
                   7504:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7505:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7506:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7507:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7508:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7509:     }
                   7510:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7511:   }
                   7512:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7513:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7514:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7515:   fprintf(ficgp,"\nset out;unset log\n");
                   7516:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7517: 
1.126     brouard  7518:   strcpy(dirfileres,optionfilefiname);
                   7519:   strcpy(optfileres,"vpl");
1.223     brouard  7520:   /* 1eme*/
1.238     brouard  7521:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7522:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7523:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7524:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7525:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7526:          continue;
                   7527:        /* We are interested in selected combination by the resultline */
1.246     brouard  7528:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7529:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7530:        strcpy(gplotlabel,"(");
1.238     brouard  7531:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7532:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7533:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7534:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7535:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7536:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7537:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7538:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7539:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7540:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7541:        }
                   7542:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7543:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7544:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7545:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7546:        }
                   7547:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7548:        /* printf("\n#\n"); */
1.238     brouard  7549:        fprintf(ficgp,"\n#\n");
                   7550:        if(invalidvarcomb[k1]){
1.260     brouard  7551:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7552:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7553:          continue;
                   7554:        }
1.235     brouard  7555:       
1.241     brouard  7556:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7557:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7558:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7559:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7560:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7561:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7562:       /* k1-1 error should be nres-1*/
1.238     brouard  7563:        for (i=1; i<= nlstate ; i ++) {
                   7564:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7565:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7566:        }
1.288     brouard  7567:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7568:        for (i=1; i<= nlstate ; i ++) {
                   7569:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7570:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7571:        } 
1.260     brouard  7572:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7573:        for (i=1; i<= nlstate ; i ++) {
                   7574:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7575:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7576:        }  
1.265     brouard  7577:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7578:        
                   7579:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7580:         if(cptcoveff ==0){
1.271     brouard  7581:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7582:        }else{
                   7583:          kl=0;
                   7584:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7585:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7586:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7587:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7588:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7589:            vlv= nbcode[Tvaraff[k]][lv];
                   7590:            kl++;
                   7591:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7592:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7593:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7594:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7595:            if(k==cptcoveff){
                   7596:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7597:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7598:            }else{
                   7599:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7600:              kl++;
                   7601:            }
                   7602:          } /* end covariate */
                   7603:        } /* end if no covariate */
                   7604: 
1.296     brouard  7605:        if(prevbcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
1.238     brouard  7606:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7607:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7608:          if(cptcoveff ==0){
1.245     brouard  7609:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7610:          }else{
                   7611:            kl=0;
                   7612:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7613:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7614:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7615:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7616:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7617:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7618:              kl++;
1.238     brouard  7619:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7620:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7621:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7622:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7623:              if(k==cptcoveff){
1.245     brouard  7624:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7625:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7626:              }else{
                   7627:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7628:                kl++;
                   7629:              }
                   7630:            } /* end covariate */
                   7631:          } /* end if no covariate */
1.296     brouard  7632:          if(prevbcast == 1){
1.268     brouard  7633:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7634:            /* k1-1 error should be nres-1*/
                   7635:            for (i=1; i<= nlstate ; i ++) {
                   7636:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7637:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7638:            }
1.271     brouard  7639:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7640:            for (i=1; i<= nlstate ; i ++) {
                   7641:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7642:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7643:            } 
1.276     brouard  7644:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7645:            for (i=1; i<= nlstate ; i ++) {
                   7646:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7647:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7648:            } 
1.274     brouard  7649:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7650:          } /* end if backprojcast */
1.296     brouard  7651:        } /* end if prevbcast */
1.276     brouard  7652:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7653:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7654:       } /* nres */
1.201     brouard  7655:     } /* k1 */
                   7656:   } /* cpt */
1.235     brouard  7657: 
                   7658:   
1.126     brouard  7659:   /*2 eme*/
1.238     brouard  7660:   for (k1=1; k1<= m ; k1 ++){  
                   7661:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7662:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7663:        continue;
                   7664:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7665:       strcpy(gplotlabel,"(");
1.238     brouard  7666:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7667:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7668:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7669:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7670:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7671:        vlv= nbcode[Tvaraff[k]][lv];
                   7672:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7673:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7674:       }
1.237     brouard  7675:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7676:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7677:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7678:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7679:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7680:       }
1.264     brouard  7681:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7682:       fprintf(ficgp,"\n#\n");
1.223     brouard  7683:       if(invalidvarcomb[k1]){
                   7684:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7685:        continue;
                   7686:       }
1.219     brouard  7687:                        
1.241     brouard  7688:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7689:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7690:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7691:        if(vpopbased==0){
1.238     brouard  7692:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7693:        }else
1.238     brouard  7694:          fprintf(ficgp,"\nreplot ");
                   7695:        for (i=1; i<= nlstate+1 ; i ++) {
                   7696:          k=2*i;
1.261     brouard  7697:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7698:          for (j=1; j<= nlstate+1 ; j ++) {
                   7699:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7700:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7701:          }   
                   7702:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7703:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7704:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7705:          for (j=1; j<= nlstate+1 ; j ++) {
                   7706:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7707:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7708:          }   
                   7709:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7710:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7711:          for (j=1; j<= nlstate+1 ; j ++) {
                   7712:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7713:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7714:          }   
                   7715:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7716:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7717:        } /* state */
                   7718:       } /* vpopbased */
1.264     brouard  7719:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7720:     } /* end nres */
                   7721:   } /* k1 end 2 eme*/
                   7722:        
                   7723:        
                   7724:   /*3eme*/
                   7725:   for (k1=1; k1<= m ; k1 ++){
                   7726:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7727:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7728:        continue;
                   7729: 
                   7730:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7731:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7732:        strcpy(gplotlabel,"(");
1.238     brouard  7733:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7734:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7735:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7736:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7737:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7738:          vlv= nbcode[Tvaraff[k]][lv];
                   7739:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7740:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7741:        }
                   7742:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7743:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7744:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7745:        }       
1.264     brouard  7746:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7747:        fprintf(ficgp,"\n#\n");
                   7748:        if(invalidvarcomb[k1]){
                   7749:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7750:          continue;
                   7751:        }
                   7752:                        
                   7753:        /*       k=2+nlstate*(2*cpt-2); */
                   7754:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7755:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7756:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7757:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7758: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7759:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7760:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7761:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7762:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7763:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7764:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7765:                                
1.238     brouard  7766:        */
                   7767:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7768:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7769:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7770:                                
1.238     brouard  7771:        } 
1.261     brouard  7772:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7773:       }
1.264     brouard  7774:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7775:     } /* end nres */
                   7776:   } /* end kl 3eme */
1.126     brouard  7777:   
1.223     brouard  7778:   /* 4eme */
1.201     brouard  7779:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7780:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7781:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7782:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7783:        continue;
1.238     brouard  7784:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7785:        strcpy(gplotlabel,"(");
1.238     brouard  7786:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7787:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7788:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7789:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7790:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7791:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7792:          vlv= nbcode[Tvaraff[k]][lv];
                   7793:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7794:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7795:        }
                   7796:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7797:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7798:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7799:        }       
1.264     brouard  7800:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7801:        fprintf(ficgp,"\n#\n");
                   7802:        if(invalidvarcomb[k1]){
                   7803:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7804:          continue;
1.223     brouard  7805:        }
1.238     brouard  7806:       
1.241     brouard  7807:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7808:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7809:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7810: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7811:        k=3;
                   7812:        for (i=1; i<= nlstate ; i ++){
                   7813:          if(i==1){
                   7814:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7815:          }else{
                   7816:            fprintf(ficgp,", '' ");
                   7817:          }
                   7818:          l=(nlstate+ndeath)*(i-1)+1;
                   7819:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7820:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7821:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7822:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7823:        } /* nlstate */
1.264     brouard  7824:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7825:       } /* end cpt state*/ 
                   7826:     } /* end nres */
                   7827:   } /* end covariate k1 */  
                   7828: 
1.220     brouard  7829: /* 5eme */
1.201     brouard  7830:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7831:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7832:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7833:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7834:        continue;
1.238     brouard  7835:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7836:        strcpy(gplotlabel,"(");
1.238     brouard  7837:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7838:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7839:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7840:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7841:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7842:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7843:          vlv= nbcode[Tvaraff[k]][lv];
                   7844:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7845:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7846:        }
                   7847:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7848:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7849:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7850:        }       
1.264     brouard  7851:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7852:        fprintf(ficgp,"\n#\n");
                   7853:        if(invalidvarcomb[k1]){
                   7854:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7855:          continue;
                   7856:        }
1.227     brouard  7857:       
1.241     brouard  7858:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7859:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7860:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7861: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7862:        k=3;
                   7863:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7864:          if(j==1)
                   7865:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7866:          else
                   7867:            fprintf(ficgp,", '' ");
                   7868:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7869:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7870:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7871:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7872:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7873:        } /* nlstate */
                   7874:        fprintf(ficgp,", '' ");
                   7875:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7876:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7877:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7878:          if(j < nlstate)
                   7879:            fprintf(ficgp,"$%d +",k+l);
                   7880:          else
                   7881:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7882:        }
1.264     brouard  7883:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7884:       } /* end cpt state*/ 
                   7885:     } /* end covariate */  
                   7886:   } /* end nres */
1.227     brouard  7887:   
1.220     brouard  7888: /* 6eme */
1.202     brouard  7889:   /* CV preval stable (period) for each covariate */
1.237     brouard  7890:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7891:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7892:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7893:       continue;
1.255     brouard  7894:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7895:       strcpy(gplotlabel,"(");      
1.288     brouard  7896:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7897:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7898:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7899:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7900:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7901:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7902:        vlv= nbcode[Tvaraff[k]][lv];
                   7903:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7904:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7905:       }
1.237     brouard  7906:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7907:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7908:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7909:       }        
1.264     brouard  7910:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7911:       fprintf(ficgp,"\n#\n");
1.223     brouard  7912:       if(invalidvarcomb[k1]){
1.227     brouard  7913:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7914:        continue;
1.223     brouard  7915:       }
1.227     brouard  7916:       
1.241     brouard  7917:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7918:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7919:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7920: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7921:       k=3; /* Offset */
1.255     brouard  7922:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7923:        if(i==1)
                   7924:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7925:        else
                   7926:          fprintf(ficgp,", '' ");
1.255     brouard  7927:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7928:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7929:        for (j=2; j<= nlstate ; j ++)
                   7930:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7931:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7932:       } /* nlstate */
1.264     brouard  7933:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7934:     } /* end cpt state*/ 
                   7935:   } /* end covariate */  
1.227     brouard  7936:   
                   7937:   
1.220     brouard  7938: /* 7eme */
1.296     brouard  7939:   if(prevbcast == 1){
1.288     brouard  7940:     /* CV backward prevalence  for each covariate */
1.237     brouard  7941:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7942:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7943:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7944:        continue;
1.268     brouard  7945:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7946:        strcpy(gplotlabel,"(");      
1.288     brouard  7947:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7948:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7949:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7950:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7951:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7952:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7953:          vlv= nbcode[Tvaraff[k]][lv];
                   7954:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7955:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7956:        }
1.237     brouard  7957:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7958:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7959:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7960:        }       
1.264     brouard  7961:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7962:        fprintf(ficgp,"\n#\n");
                   7963:        if(invalidvarcomb[k1]){
                   7964:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7965:          continue;
                   7966:        }
                   7967:        
1.241     brouard  7968:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7969:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7970:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7971: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7972:        k=3; /* Offset */
1.268     brouard  7973:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7974:          if(i==1)
                   7975:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7976:          else
                   7977:            fprintf(ficgp,", '' ");
                   7978:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7979:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7980:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7981:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7982:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7983:          /* for (j=2; j<= nlstate ; j ++) */
                   7984:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7985:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7986:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7987:        } /* nlstate */
1.264     brouard  7988:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7989:       } /* end cpt state*/ 
                   7990:     } /* end covariate */  
1.296     brouard  7991:   } /* End if prevbcast */
1.218     brouard  7992:   
1.223     brouard  7993:   /* 8eme */
1.218     brouard  7994:   if(prevfcast==1){
1.288     brouard  7995:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  7996:     
1.237     brouard  7997:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7998:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7999:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  8000:        continue;
1.211     brouard  8001:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  8002:        strcpy(gplotlabel,"(");      
1.288     brouard  8003:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  8004:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8005:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8006:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8007:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8008:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8009:          vlv= nbcode[Tvaraff[k]][lv];
                   8010:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  8011:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  8012:        }
1.237     brouard  8013:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8014:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  8015:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  8016:        }       
1.264     brouard  8017:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  8018:        fprintf(ficgp,"\n#\n");
                   8019:        if(invalidvarcomb[k1]){
                   8020:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   8021:          continue;
                   8022:        }
                   8023:        
                   8024:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  8025:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  8026:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  8027:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  8028: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  8029: 
                   8030:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   8031:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8032:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8033:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  8034:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8035:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   8036:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8037:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  8038:          if(i==istart){
1.227     brouard  8039:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   8040:          }else{
                   8041:            fprintf(ficgp,",\\\n '' ");
                   8042:          }
                   8043:          if(cptcoveff ==0){ /* No covariate */
                   8044:            ioffset=2; /* Age is in 2 */
                   8045:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8046:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8047:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8048:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8049:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  8050:            if(i==nlstate+1){
1.270     brouard  8051:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  8052:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   8053:              fprintf(ficgp,",\\\n '' ");
                   8054:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  8055:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  8056:                     offyear,                           \
1.268     brouard  8057:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  8058:            }else
1.227     brouard  8059:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   8060:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   8061:          }else{ /* more than 2 covariates */
1.270     brouard  8062:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   8063:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8064:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   8065:            iyearc=ioffset-1;
                   8066:            iagec=ioffset;
1.227     brouard  8067:            fprintf(ficgp," u %d:(",ioffset); 
                   8068:            kl=0;
                   8069:            strcpy(gplotcondition,"(");
                   8070:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   8071:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   8072:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8073:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8074:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8075:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   8076:              kl++;
                   8077:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   8078:              kl++;
                   8079:              if(k <cptcoveff && cptcoveff>1)
                   8080:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   8081:            }
                   8082:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   8083:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   8084:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   8085:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   8086:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   8087:            if(i==nlstate+1){
1.270     brouard  8088:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   8089:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  8090:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  8091:              fprintf(ficgp," u %d:(",iagec); 
                   8092:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   8093:                      iyearc, iagec, offyear,                           \
                   8094:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  8095: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  8096:            }else{
                   8097:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   8098:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   8099:            }
                   8100:          } /* end if covariate */
                   8101:        } /* nlstate */
1.264     brouard  8102:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  8103:       } /* end cpt state*/
                   8104:     } /* end covariate */
                   8105:   } /* End if prevfcast */
1.227     brouard  8106:   
1.296     brouard  8107:   if(prevbcast==1){
1.268     brouard  8108:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   8109:     
                   8110:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   8111:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   8112:       if(m != 1 && TKresult[nres]!= k1)
                   8113:        continue;
                   8114:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   8115:        strcpy(gplotlabel,"(");      
                   8116:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   8117:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8118:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8119:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8120:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8121:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8122:          vlv= nbcode[Tvaraff[k]][lv];
                   8123:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   8124:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   8125:        }
                   8126:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8127:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8128:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8129:        }       
                   8130:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   8131:        fprintf(ficgp,"\n#\n");
                   8132:        if(invalidvarcomb[k1]){
                   8133:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   8134:          continue;
                   8135:        }
                   8136:        
                   8137:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   8138:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   8139:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   8140:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   8141: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   8142: 
                   8143:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   8144:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8145:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8146:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   8147:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8148:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   8149:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8150:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   8151:          if(i==istart){
                   8152:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   8153:          }else{
                   8154:            fprintf(ficgp,",\\\n '' ");
                   8155:          }
                   8156:          if(cptcoveff ==0){ /* No covariate */
                   8157:            ioffset=2; /* Age is in 2 */
                   8158:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8159:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8160:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8161:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8162:            fprintf(ficgp," u %d:(", ioffset); 
                   8163:            if(i==nlstate+1){
1.270     brouard  8164:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  8165:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   8166:              fprintf(ficgp,",\\\n '' ");
                   8167:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  8168:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  8169:                     offbyear,                          \
                   8170:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   8171:            }else
                   8172:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   8173:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   8174:          }else{ /* more than 2 covariates */
1.270     brouard  8175:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   8176:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8177:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   8178:            iyearc=ioffset-1;
                   8179:            iagec=ioffset;
1.268     brouard  8180:            fprintf(ficgp," u %d:(",ioffset); 
                   8181:            kl=0;
                   8182:            strcpy(gplotcondition,"(");
                   8183:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   8184:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   8185:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8186:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8187:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8188:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   8189:              kl++;
                   8190:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   8191:              kl++;
                   8192:              if(k <cptcoveff && cptcoveff>1)
                   8193:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   8194:            }
                   8195:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   8196:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   8197:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   8198:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   8199:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   8200:            if(i==nlstate+1){
1.270     brouard  8201:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   8202:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  8203:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  8204:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  8205:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  8206:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   8207:                      iyearc,iagec,offbyear,                            \
                   8208:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  8209: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   8210:            }else{
                   8211:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   8212:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   8213:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   8214:            }
                   8215:          } /* end if covariate */
                   8216:        } /* nlstate */
                   8217:        fprintf(ficgp,"\nset out; unset label;\n");
                   8218:       } /* end cpt state*/
                   8219:     } /* end covariate */
1.296     brouard  8220:   } /* End if prevbcast */
1.268     brouard  8221:   
1.227     brouard  8222:   
1.238     brouard  8223:   /* 9eme writing MLE parameters */
                   8224:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  8225:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  8226:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  8227:     for(k=1; k <=(nlstate+ndeath); k++){
                   8228:       if (k != i) {
1.227     brouard  8229:        fprintf(ficgp,"#   current state %d\n",k);
                   8230:        for(j=1; j <=ncovmodel; j++){
                   8231:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   8232:          jk++; 
                   8233:        }
                   8234:        fprintf(ficgp,"\n");
1.126     brouard  8235:       }
                   8236:     }
1.223     brouard  8237:   }
1.187     brouard  8238:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  8239:   
1.145     brouard  8240:   /*goto avoid;*/
1.238     brouard  8241:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   8242:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  8243:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   8244:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   8245:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   8246:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   8247:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8248:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8249:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8250:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8251:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   8252:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8253:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   8254:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   8255:   fprintf(ficgp,"#\n");
1.223     brouard  8256:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  8257:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  8258:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  8259:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  8260:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   8261:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  8262:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  8263:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  8264:        continue;
1.264     brouard  8265:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   8266:       strcpy(gplotlabel,"(");
1.276     brouard  8267:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  8268:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8269:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8270:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8271:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8272:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8273:        vlv= nbcode[Tvaraff[k]][lv];
                   8274:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   8275:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   8276:       }
1.237     brouard  8277:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8278:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  8279:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  8280:       }        
1.264     brouard  8281:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  8282:       fprintf(ficgp,"\n#\n");
1.264     brouard  8283:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  8284:       fprintf(ficgp,"\nset key outside ");
                   8285:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   8286:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  8287:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   8288:       if (ng==1){
                   8289:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   8290:        fprintf(ficgp,"\nunset log y");
                   8291:       }else if (ng==2){
                   8292:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   8293:        fprintf(ficgp,"\nset log y");
                   8294:       }else if (ng==3){
                   8295:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   8296:        fprintf(ficgp,"\nset log y");
                   8297:       }else
                   8298:        fprintf(ficgp,"\nunset title ");
                   8299:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   8300:       i=1;
                   8301:       for(k2=1; k2<=nlstate; k2++) {
                   8302:        k3=i;
                   8303:        for(k=1; k<=(nlstate+ndeath); k++) {
                   8304:          if (k != k2){
                   8305:            switch( ng) {
                   8306:            case 1:
                   8307:              if(nagesqr==0)
                   8308:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   8309:              else /* nagesqr =1 */
                   8310:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8311:              break;
                   8312:            case 2: /* ng=2 */
                   8313:              if(nagesqr==0)
                   8314:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   8315:              else /* nagesqr =1 */
                   8316:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8317:              break;
                   8318:            case 3:
                   8319:              if(nagesqr==0)
                   8320:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   8321:              else /* nagesqr =1 */
                   8322:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   8323:              break;
                   8324:            }
                   8325:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  8326:            ijp=1; /* product no age */
                   8327:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   8328:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  8329:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  8330:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8331:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   8332:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8333:                    if(DummyV[j]==0){
                   8334:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   8335:                    }else{ /* quantitative */
                   8336:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   8337:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8338:                    }
                   8339:                    ij++;
1.237     brouard  8340:                  }
1.268     brouard  8341:                } 
                   8342:              }else if(cptcovprod >0){
                   8343:                if(j==Tprod[ijp]) { /* */ 
                   8344:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   8345:                  if(ijp <=cptcovprod) { /* Product */
                   8346:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   8347:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   8348:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   8349:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   8350:                      }else{ /* Vn is dummy and Vm is quanti */
                   8351:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   8352:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8353:                      }
                   8354:                    }else{ /* Vn*Vm Vn is quanti */
                   8355:                      if(DummyV[Tvard[ijp][2]]==0){
                   8356:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   8357:                      }else{ /* Both quanti */
                   8358:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8359:                      }
1.237     brouard  8360:                    }
1.268     brouard  8361:                    ijp++;
1.237     brouard  8362:                  }
1.268     brouard  8363:                } /* end Tprod */
1.237     brouard  8364:              } else{  /* simple covariate */
1.264     brouard  8365:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  8366:                if(Dummy[j]==0){
                   8367:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   8368:                }else{ /* quantitative */
                   8369:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  8370:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  8371:                }
1.237     brouard  8372:              } /* end simple */
                   8373:            } /* end j */
1.223     brouard  8374:          }else{
                   8375:            i=i-ncovmodel;
                   8376:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   8377:              fprintf(ficgp," (1.");
                   8378:          }
1.227     brouard  8379:          
1.223     brouard  8380:          if(ng != 1){
                   8381:            fprintf(ficgp,")/(1");
1.227     brouard  8382:            
1.264     brouard  8383:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8384:              if(nagesqr==0)
1.264     brouard  8385:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8386:              else /* nagesqr =1 */
1.264     brouard  8387:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8388:               
1.223     brouard  8389:              ij=1;
                   8390:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8391:                 if(cptcovage >0){ 
                   8392:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8393:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8394:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8395:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8396:                       ij++;
                   8397:                     }
                   8398:                   }
                   8399:                 }else
                   8400:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8401:              }
                   8402:              fprintf(ficgp,")");
                   8403:            }
                   8404:            fprintf(ficgp,")");
                   8405:            if(ng ==2)
1.276     brouard  8406:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8407:            else /* ng= 3 */
1.276     brouard  8408:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8409:          }else{ /* end ng <> 1 */
                   8410:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8411:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8412:          }
                   8413:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8414:            fprintf(ficgp,",");
                   8415:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8416:            fprintf(ficgp,",");
                   8417:          i=i+ncovmodel;
                   8418:        } /* end k */
                   8419:       } /* end k2 */
1.276     brouard  8420:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8421:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8422:     } /* end k1 */
1.223     brouard  8423:   } /* end ng */
                   8424:   /* avoid: */
                   8425:   fflush(ficgp); 
1.126     brouard  8426: }  /* end gnuplot */
                   8427: 
                   8428: 
                   8429: /*************** Moving average **************/
1.219     brouard  8430: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8431:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8432:    
1.222     brouard  8433:    int i, cpt, cptcod;
                   8434:    int modcovmax =1;
                   8435:    int mobilavrange, mob;
                   8436:    int iage=0;
1.288     brouard  8437:    int firstA1=0, firstA2=0;
1.222     brouard  8438: 
1.266     brouard  8439:    double sum=0., sumr=0.;
1.222     brouard  8440:    double age;
1.266     brouard  8441:    double *sumnewp, *sumnewm, *sumnewmr;
                   8442:    double *agemingood, *agemaxgood; 
                   8443:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8444:   
                   8445:   
1.278     brouard  8446:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8447:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8448: 
                   8449:    sumnewp = vector(1,ncovcombmax);
                   8450:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8451:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8452:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8453:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8454:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8455:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8456: 
                   8457:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8458:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8459:      sumnewp[cptcod]=0.;
1.266     brouard  8460:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8461:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8462:    }
                   8463:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8464:   
1.266     brouard  8465:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8466:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8467:      else mobilavrange=mobilav;
                   8468:      for (age=bage; age<=fage; age++)
                   8469:        for (i=1; i<=nlstate;i++)
                   8470:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8471:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8472:      /* We keep the original values on the extreme ages bage, fage and for 
                   8473:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8474:        we use a 5 terms etc. until the borders are no more concerned. 
                   8475:      */ 
                   8476:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8477:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8478:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8479:           sumnewm[cptcod]=0.;
                   8480:           for (i=1; i<=nlstate;i++){
1.222     brouard  8481:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8482:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8483:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8484:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8485:             }
                   8486:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8487:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8488:           } /* end i */
                   8489:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8490:         } /* end cptcod */
1.222     brouard  8491:        }/* end age */
                   8492:      }/* end mob */
1.266     brouard  8493:    }else{
                   8494:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8495:      return -1;
1.266     brouard  8496:    }
                   8497: 
                   8498:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8499:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8500:      if(invalidvarcomb[cptcod]){
                   8501:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8502:        continue;
                   8503:      }
1.219     brouard  8504: 
1.266     brouard  8505:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8506:        sumnewm[cptcod]=0.;
                   8507:        sumnewmr[cptcod]=0.;
                   8508:        for (i=1; i<=nlstate;i++){
                   8509:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8510:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8511:        }
                   8512:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8513:         agemingoodr[cptcod]=age;
                   8514:        }
                   8515:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8516:           agemingood[cptcod]=age;
                   8517:        }
                   8518:      } /* age */
                   8519:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8520:        sumnewm[cptcod]=0.;
1.266     brouard  8521:        sumnewmr[cptcod]=0.;
1.222     brouard  8522:        for (i=1; i<=nlstate;i++){
                   8523:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8524:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8525:        }
                   8526:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8527:         agemaxgoodr[cptcod]=age;
1.222     brouard  8528:        }
                   8529:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8530:         agemaxgood[cptcod]=age;
                   8531:        }
                   8532:      } /* age */
                   8533:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8534:      /* but they will change */
1.288     brouard  8535:      firstA1=0;firstA2=0;
1.266     brouard  8536:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8537:        sumnewm[cptcod]=0.;
                   8538:        sumnewmr[cptcod]=0.;
                   8539:        for (i=1; i<=nlstate;i++){
                   8540:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8541:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8542:        }
                   8543:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8544:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8545:           agemaxgoodr[cptcod]=age;  /* age min */
                   8546:           for (i=1; i<=nlstate;i++)
                   8547:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8548:         }else{ /* bad we change the value with the values of good ages */
                   8549:           for (i=1; i<=nlstate;i++){
                   8550:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8551:           } /* i */
                   8552:         } /* end bad */
                   8553:        }else{
                   8554:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8555:           agemaxgood[cptcod]=age;
                   8556:         }else{ /* bad we change the value with the values of good ages */
                   8557:           for (i=1; i<=nlstate;i++){
                   8558:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8559:           } /* i */
                   8560:         } /* end bad */
                   8561:        }/* end else */
                   8562:        sum=0.;sumr=0.;
                   8563:        for (i=1; i<=nlstate;i++){
                   8564:         sum+=mobaverage[(int)age][i][cptcod];
                   8565:         sumr+=probs[(int)age][i][cptcod];
                   8566:        }
                   8567:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8568:         if(!firstA1){
                   8569:           firstA1=1;
                   8570:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8571:         }
                   8572:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8573:        } /* end bad */
                   8574:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8575:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8576:         if(!firstA2){
                   8577:           firstA2=1;
                   8578:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8579:         }
                   8580:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8581:        } /* end bad */
                   8582:      }/* age */
1.266     brouard  8583: 
                   8584:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8585:        sumnewm[cptcod]=0.;
1.266     brouard  8586:        sumnewmr[cptcod]=0.;
1.222     brouard  8587:        for (i=1; i<=nlstate;i++){
                   8588:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8589:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8590:        } 
                   8591:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8592:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8593:           agemingoodr[cptcod]=age;
                   8594:           for (i=1; i<=nlstate;i++)
                   8595:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8596:         }else{ /* bad we change the value with the values of good ages */
                   8597:           for (i=1; i<=nlstate;i++){
                   8598:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8599:           } /* i */
                   8600:         } /* end bad */
                   8601:        }else{
                   8602:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8603:           agemingood[cptcod]=age;
                   8604:         }else{ /* bad */
                   8605:           for (i=1; i<=nlstate;i++){
                   8606:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8607:           } /* i */
                   8608:         } /* end bad */
                   8609:        }/* end else */
                   8610:        sum=0.;sumr=0.;
                   8611:        for (i=1; i<=nlstate;i++){
                   8612:         sum+=mobaverage[(int)age][i][cptcod];
                   8613:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8614:        }
1.266     brouard  8615:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8616:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8617:        } /* end bad */
                   8618:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8619:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8620:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8621:        } /* end bad */
                   8622:      }/* age */
1.266     brouard  8623: 
1.222     brouard  8624:                
                   8625:      for (age=bage; age<=fage; age++){
1.235     brouard  8626:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8627:        sumnewp[cptcod]=0.;
                   8628:        sumnewm[cptcod]=0.;
                   8629:        for (i=1; i<=nlstate;i++){
                   8630:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8631:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8632:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8633:        }
                   8634:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8635:      }
                   8636:      /* printf("\n"); */
                   8637:      /* } */
1.266     brouard  8638: 
1.222     brouard  8639:      /* brutal averaging */
1.266     brouard  8640:      /* for (i=1; i<=nlstate;i++){ */
                   8641:      /*   for (age=1; age<=bage; age++){ */
                   8642:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8643:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8644:      /*   }     */
                   8645:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8646:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8647:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8648:      /*   } */
                   8649:      /* } /\* end i status *\/ */
                   8650:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8651:      /*   for (age=1; age<=AGESUP; age++){ */
                   8652:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8653:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8654:      /*   } */
                   8655:      /* } */
1.222     brouard  8656:    }/* end cptcod */
1.266     brouard  8657:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8658:    free_vector(agemaxgood,1, ncovcombmax);
                   8659:    free_vector(agemingood,1, ncovcombmax);
                   8660:    free_vector(agemingoodr,1, ncovcombmax);
                   8661:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8662:    free_vector(sumnewm,1, ncovcombmax);
                   8663:    free_vector(sumnewp,1, ncovcombmax);
                   8664:    return 0;
                   8665:  }/* End movingaverage */
1.218     brouard  8666:  
1.126     brouard  8667: 
1.296     brouard  8668:  
1.126     brouard  8669: /************** Forecasting ******************/
1.296     brouard  8670: /* void prevforecast(char fileres[], double dateintmean, double anprojd, double mprojd, double jprojd, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anprojf, double p[], int cptcoveff)*/
                   8671: void prevforecast(char fileres[], double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8672:   /* dateintemean, mean date of interviews
                   8673:      dateprojd, year, month, day of starting projection 
                   8674:      dateprojf date of end of projection;year of end of projection (same day and month as proj1).
1.126     brouard  8675:      agemin, agemax range of age
                   8676:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8677:   */
1.296     brouard  8678:   /* double anprojd, mprojd, jprojd; */
                   8679:   /* double anprojf, mprojf, jprojf; */
1.267     brouard  8680:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8681:   double agec; /* generic age */
1.296     brouard  8682:   double agelim, ppij, yp,yp1,yp2;
1.126     brouard  8683:   double *popeffectif,*popcount;
                   8684:   double ***p3mat;
1.218     brouard  8685:   /* double ***mobaverage; */
1.126     brouard  8686:   char fileresf[FILENAMELENGTH];
                   8687: 
                   8688:   agelim=AGESUP;
1.211     brouard  8689:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8690:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8691:      We still use firstpass and lastpass as another selection.
                   8692:   */
1.214     brouard  8693:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8694:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8695:  
1.201     brouard  8696:   strcpy(fileresf,"F_"); 
                   8697:   strcat(fileresf,fileresu);
1.126     brouard  8698:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8699:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8700:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8701:   }
1.235     brouard  8702:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8703:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8704: 
1.225     brouard  8705:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8706: 
                   8707: 
                   8708:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8709:   if (stepm<=12) stepsize=1;
                   8710:   if(estepm < stepm){
                   8711:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8712:   }
1.270     brouard  8713:   else{
                   8714:     hstepm=estepm;   
                   8715:   }
                   8716:   if(estepm > stepm){ /* Yes every two year */
                   8717:     stepsize=2;
                   8718:   }
1.296     brouard  8719:   hstepm=hstepm/stepm;
1.126     brouard  8720: 
1.296     brouard  8721:   
                   8722:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8723:   /*                              fractional in yp1 *\/ */
                   8724:   /* aintmean=yp; */
                   8725:   /* yp2=modf((yp1*12),&yp); */
                   8726:   /* mintmean=yp; */
                   8727:   /* yp1=modf((yp2*30.5),&yp); */
                   8728:   /* jintmean=yp; */
                   8729:   /* if(jintmean==0) jintmean=1; */
                   8730:   /* if(mintmean==0) mintmean=1; */
1.126     brouard  8731: 
1.296     brouard  8732: 
                   8733:   /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */
                   8734:   /* date2dmy(dateprojd,&jprojd, &mprojd, &anprojd); */
                   8735:   /* date2dmy(dateprojf,&jprojf, &mprojf, &anprojf); */
1.227     brouard  8736:   i1=pow(2,cptcoveff);
1.126     brouard  8737:   if (cptcovn < 1){i1=1;}
                   8738:   
1.296     brouard  8739:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2); 
1.126     brouard  8740:   
                   8741:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8742:   
1.126     brouard  8743: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8744:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8745:   for(k=1; k<=i1;k++){
1.253     brouard  8746:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8747:       continue;
1.227     brouard  8748:     if(invalidvarcomb[k]){
                   8749:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8750:       continue;
                   8751:     }
                   8752:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8753:     for(j=1;j<=cptcoveff;j++) {
                   8754:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8755:     }
1.235     brouard  8756:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8757:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8758:     }
1.227     brouard  8759:     fprintf(ficresf," yearproj age");
                   8760:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8761:       for(i=1; i<=nlstate;i++)               
                   8762:        fprintf(ficresf," p%d%d",i,j);
                   8763:       fprintf(ficresf," wp.%d",j);
                   8764:     }
1.296     brouard  8765:     for (yearp=0; yearp<=(anprojf-anprojd);yearp +=stepsize) {
1.227     brouard  8766:       fprintf(ficresf,"\n");
1.296     brouard  8767:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jprojd,mprojd,anprojd+yearp);   
1.270     brouard  8768:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8769:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8770:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8771:        nhstepm = nhstepm/hstepm; 
                   8772:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8773:        oldm=oldms;savm=savms;
1.268     brouard  8774:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8775:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8776:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8777:        for (h=0; h<=nhstepm; h++){
                   8778:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8779:            break;
                   8780:          }
                   8781:        }
                   8782:        fprintf(ficresf,"\n");
                   8783:        for(j=1;j<=cptcoveff;j++) 
                   8784:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8785:        fprintf(ficresf,"%.f %.f ",anprojd+yearp,agec+h*hstepm/YEARM*stepm);
1.268     brouard  8786:        
                   8787:        for(j=1; j<=nlstate+ndeath;j++) {
                   8788:          ppij=0.;
                   8789:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8790:            if (mobilav>=1)
                   8791:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8792:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8793:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8794:            }
1.268     brouard  8795:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8796:          } /* end i */
                   8797:          fprintf(ficresf," %.3f", ppij);
                   8798:        }/* end j */
1.227     brouard  8799:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8800:       } /* end agec */
1.266     brouard  8801:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8802:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8803:     } /* end yearp */
                   8804:   } /* end  k */
1.219     brouard  8805:        
1.126     brouard  8806:   fclose(ficresf);
1.215     brouard  8807:   printf("End of Computing forecasting \n");
                   8808:   fprintf(ficlog,"End of Computing forecasting\n");
                   8809: 
1.126     brouard  8810: }
                   8811: 
1.269     brouard  8812: /************** Back Forecasting ******************/
1.296     brouard  8813:  /* void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
                   8814:  void prevbackforecast(char fileres[], double ***prevacurrent, double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8815:   /* back1, year, month, day of starting backprojection
1.267     brouard  8816:      agemin, agemax range of age
                   8817:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8818:      anback2 year of end of backprojection (same day and month as back1).
                   8819:      prevacurrent and prev are prevalences.
1.267     brouard  8820:   */
                   8821:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8822:   double agec; /* generic age */
1.302     brouard  8823:   double agelim, ppij, ppi, yp,yp1,yp2; /* ,jintmean,mintmean,aintmean;*/
1.267     brouard  8824:   double *popeffectif,*popcount;
                   8825:   double ***p3mat;
                   8826:   /* double ***mobaverage; */
                   8827:   char fileresfb[FILENAMELENGTH];
                   8828:  
1.268     brouard  8829:   agelim=AGEINF;
1.267     brouard  8830:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8831:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8832:      We still use firstpass and lastpass as another selection.
                   8833:   */
                   8834:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8835:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8836: 
                   8837:   /*Do we need to compute prevalence again?*/
                   8838: 
                   8839:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8840:   
                   8841:   strcpy(fileresfb,"FB_");
                   8842:   strcat(fileresfb,fileresu);
                   8843:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8844:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8845:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8846:   }
                   8847:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8848:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8849:   
                   8850:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8851:   
                   8852:    
                   8853:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8854:   if (stepm<=12) stepsize=1;
                   8855:   if(estepm < stepm){
                   8856:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8857:   }
1.270     brouard  8858:   else{
                   8859:     hstepm=estepm;   
                   8860:   }
                   8861:   if(estepm >= stepm){ /* Yes every two year */
                   8862:     stepsize=2;
                   8863:   }
1.267     brouard  8864:   
                   8865:   hstepm=hstepm/stepm;
1.296     brouard  8866:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8867:   /*                              fractional in yp1 *\/ */
                   8868:   /* aintmean=yp; */
                   8869:   /* yp2=modf((yp1*12),&yp); */
                   8870:   /* mintmean=yp; */
                   8871:   /* yp1=modf((yp2*30.5),&yp); */
                   8872:   /* jintmean=yp; */
                   8873:   /* if(jintmean==0) jintmean=1; */
                   8874:   /* if(mintmean==0) jintmean=1; */
1.267     brouard  8875:   
                   8876:   i1=pow(2,cptcoveff);
                   8877:   if (cptcovn < 1){i1=1;}
                   8878:   
1.296     brouard  8879:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
                   8880:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8881:   
                   8882:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8883:   
                   8884:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8885:   for(k=1; k<=i1;k++){
                   8886:     if(i1 != 1 && TKresult[nres]!= k)
                   8887:       continue;
                   8888:     if(invalidvarcomb[k]){
                   8889:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8890:       continue;
                   8891:     }
1.268     brouard  8892:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8893:     for(j=1;j<=cptcoveff;j++) {
                   8894:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8895:     }
                   8896:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8897:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8898:     }
                   8899:     fprintf(ficresfb," yearbproj age");
                   8900:     for(j=1; j<=nlstate+ndeath;j++){
                   8901:       for(i=1; i<=nlstate;i++)
1.268     brouard  8902:        fprintf(ficresfb," b%d%d",i,j);
                   8903:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8904:     }
1.296     brouard  8905:     for (yearp=0; yearp>=(anbackf-anbackd);yearp -=stepsize) {
1.267     brouard  8906:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8907:       fprintf(ficresfb,"\n");
1.296     brouard  8908:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jbackd,mbackd,anbackd+yearp);
1.273     brouard  8909:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8910:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8911:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8912:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8913:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8914:        nhstepm = nhstepm/hstepm;
                   8915:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8916:        oldm=oldms;savm=savms;
1.268     brouard  8917:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8918:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8919:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8920:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8921:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8922:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8923:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8924:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8925:            break;
                   8926:          }
                   8927:        }
                   8928:        fprintf(ficresfb,"\n");
                   8929:        for(j=1;j<=cptcoveff;j++)
                   8930:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8931:        fprintf(ficresfb,"%.f %.f ",anbackd+yearp,agec-h*hstepm/YEARM*stepm);
1.268     brouard  8932:        for(i=1; i<=nlstate+ndeath;i++) {
                   8933:          ppij=0.;ppi=0.;
                   8934:          for(j=1; j<=nlstate;j++) {
                   8935:            /* if (mobilav==1) */
1.269     brouard  8936:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8937:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8938:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8939:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8940:              /* else { */
                   8941:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8942:              /* } */
1.268     brouard  8943:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8944:          } /* end j */
                   8945:          if(ppi <0.99){
                   8946:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8947:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8948:          }
                   8949:          fprintf(ficresfb," %.3f", ppij);
                   8950:        }/* end j */
1.267     brouard  8951:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8952:       } /* end agec */
                   8953:     } /* end yearp */
                   8954:   } /* end k */
1.217     brouard  8955:   
1.267     brouard  8956:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8957:   
1.267     brouard  8958:   fclose(ficresfb);
                   8959:   printf("End of Computing Back forecasting \n");
                   8960:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8961:        
1.267     brouard  8962: }
1.217     brouard  8963: 
1.269     brouard  8964: /* Variance of prevalence limit: varprlim */
                   8965:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8966:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8967:  
                   8968:    char fileresvpl[FILENAMELENGTH];  
                   8969:    FILE *ficresvpl;
                   8970:    double **oldm, **savm;
                   8971:    double **varpl; /* Variances of prevalence limits by age */   
                   8972:    int i1, k, nres, j ;
                   8973:    
                   8974:     strcpy(fileresvpl,"VPL_");
                   8975:     strcat(fileresvpl,fileresu);
                   8976:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8977:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8978:       exit(0);
                   8979:     }
1.288     brouard  8980:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8981:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8982:     
                   8983:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8984:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8985:     
                   8986:     i1=pow(2,cptcoveff);
                   8987:     if (cptcovn < 1){i1=1;}
                   8988: 
                   8989:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8990:     for(k=1; k<=i1;k++){
                   8991:       if(i1 != 1 && TKresult[nres]!= k)
                   8992:        continue;
                   8993:       fprintf(ficresvpl,"\n#****** ");
                   8994:       printf("\n#****** ");
                   8995:       fprintf(ficlog,"\n#****** ");
                   8996:       for(j=1;j<=cptcoveff;j++) {
                   8997:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8998:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8999:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9000:       }
                   9001:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9002:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9003:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9004:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9005:       }        
                   9006:       fprintf(ficresvpl,"******\n");
                   9007:       printf("******\n");
                   9008:       fprintf(ficlog,"******\n");
                   9009:       
                   9010:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   9011:       oldm=oldms;savm=savms;
                   9012:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   9013:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   9014:       /*}*/
                   9015:     }
                   9016:     
                   9017:     fclose(ficresvpl);
1.288     brouard  9018:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   9019:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  9020: 
                   9021:  }
                   9022: /* Variance of back prevalence: varbprlim */
                   9023:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   9024:       /*------- Variance of back (stable) prevalence------*/
                   9025: 
                   9026:    char fileresvbl[FILENAMELENGTH];  
                   9027:    FILE  *ficresvbl;
                   9028: 
                   9029:    double **oldm, **savm;
                   9030:    double **varbpl; /* Variances of back prevalence limits by age */   
                   9031:    int i1, k, nres, j ;
                   9032: 
                   9033:    strcpy(fileresvbl,"VBL_");
                   9034:    strcat(fileresvbl,fileresu);
                   9035:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   9036:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   9037:      exit(0);
                   9038:    }
                   9039:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   9040:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   9041:    
                   9042:    
                   9043:    i1=pow(2,cptcoveff);
                   9044:    if (cptcovn < 1){i1=1;}
                   9045:    
                   9046:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9047:      for(k=1; k<=i1;k++){
                   9048:        if(i1 != 1 && TKresult[nres]!= k)
                   9049:         continue;
                   9050:        fprintf(ficresvbl,"\n#****** ");
                   9051:        printf("\n#****** ");
                   9052:        fprintf(ficlog,"\n#****** ");
                   9053:        for(j=1;j<=cptcoveff;j++) {
                   9054:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9055:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9056:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9057:        }
                   9058:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9059:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9060:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9061:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9062:        }
                   9063:        fprintf(ficresvbl,"******\n");
                   9064:        printf("******\n");
                   9065:        fprintf(ficlog,"******\n");
                   9066:        
                   9067:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   9068:        oldm=oldms;savm=savms;
                   9069:        
                   9070:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   9071:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   9072:        /*}*/
                   9073:      }
                   9074:    
                   9075:    fclose(ficresvbl);
                   9076:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   9077:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   9078: 
                   9079:  } /* End of varbprlim */
                   9080: 
1.126     brouard  9081: /************** Forecasting *****not tested NB*************/
1.227     brouard  9082: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  9083:   
1.227     brouard  9084: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   9085: /*   int *popage; */
                   9086: /*   double calagedatem, agelim, kk1, kk2; */
                   9087: /*   double *popeffectif,*popcount; */
                   9088: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   9089: /*   /\* double ***mobaverage; *\/ */
                   9090: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  9091: 
1.227     brouard  9092: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9093: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9094: /*   agelim=AGESUP; */
                   9095: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  9096:   
1.227     brouard  9097: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  9098:   
                   9099:   
1.227     brouard  9100: /*   strcpy(filerespop,"POP_");  */
                   9101: /*   strcat(filerespop,fileresu); */
                   9102: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   9103: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   9104: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   9105: /*   } */
                   9106: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   9107: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  9108: 
1.227     brouard  9109: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  9110: 
1.227     brouard  9111: /*   /\* if (mobilav!=0) { *\/ */
                   9112: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   9113: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   9114: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   9115: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   9116: /*   /\*   } *\/ */
                   9117: /*   /\* } *\/ */
1.126     brouard  9118: 
1.227     brouard  9119: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   9120: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  9121:   
1.227     brouard  9122: /*   agelim=AGESUP; */
1.126     brouard  9123:   
1.227     brouard  9124: /*   hstepm=1; */
                   9125: /*   hstepm=hstepm/stepm;  */
1.218     brouard  9126:        
1.227     brouard  9127: /*   if (popforecast==1) { */
                   9128: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   9129: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   9130: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   9131: /*     }  */
                   9132: /*     popage=ivector(0,AGESUP); */
                   9133: /*     popeffectif=vector(0,AGESUP); */
                   9134: /*     popcount=vector(0,AGESUP); */
1.126     brouard  9135:     
1.227     brouard  9136: /*     i=1;    */
                   9137: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  9138:     
1.227     brouard  9139: /*     imx=i; */
                   9140: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   9141: /*   } */
1.218     brouard  9142:   
1.227     brouard  9143: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   9144: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   9145: /*       k=k+1; */
                   9146: /*       fprintf(ficrespop,"\n#******"); */
                   9147: /*       for(j=1;j<=cptcoveff;j++) { */
                   9148: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   9149: /*       } */
                   9150: /*       fprintf(ficrespop,"******\n"); */
                   9151: /*       fprintf(ficrespop,"# Age"); */
                   9152: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   9153: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  9154:       
1.227     brouard  9155: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   9156: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  9157:        
1.227     brouard  9158: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   9159: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   9160: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  9161:          
1.227     brouard  9162: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9163: /*       oldm=oldms;savm=savms; */
                   9164: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  9165:          
1.227     brouard  9166: /*       for (h=0; h<=nhstepm; h++){ */
                   9167: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   9168: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   9169: /*         }  */
                   9170: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   9171: /*           kk1=0.;kk2=0; */
                   9172: /*           for(i=1; i<=nlstate;i++) {               */
                   9173: /*             if (mobilav==1)  */
                   9174: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   9175: /*             else { */
                   9176: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   9177: /*             } */
                   9178: /*           } */
                   9179: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   9180: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   9181: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   9182: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   9183: /*           } */
                   9184: /*         } */
                   9185: /*         for(i=1; i<=nlstate;i++){ */
                   9186: /*           kk1=0.; */
                   9187: /*           for(j=1; j<=nlstate;j++){ */
                   9188: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   9189: /*           } */
                   9190: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   9191: /*         } */
1.218     brouard  9192:            
1.227     brouard  9193: /*         if (h==(int)(calagedatem+12*cpt)) */
                   9194: /*           for(j=1; j<=nlstate;j++)  */
                   9195: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   9196: /*       } */
                   9197: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9198: /*     } */
                   9199: /*       } */
1.218     brouard  9200:       
1.227     brouard  9201: /*       /\******\/ */
1.218     brouard  9202:       
1.227     brouard  9203: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   9204: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   9205: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   9206: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   9207: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  9208:          
1.227     brouard  9209: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9210: /*       oldm=oldms;savm=savms; */
                   9211: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9212: /*       for (h=0; h<=nhstepm; h++){ */
                   9213: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   9214: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   9215: /*         }  */
                   9216: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   9217: /*           kk1=0.;kk2=0; */
                   9218: /*           for(i=1; i<=nlstate;i++) {               */
                   9219: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   9220: /*           } */
                   9221: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   9222: /*         } */
                   9223: /*       } */
                   9224: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9225: /*     } */
                   9226: /*       } */
                   9227: /*     }  */
                   9228: /*   } */
1.218     brouard  9229:   
1.227     brouard  9230: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  9231:   
1.227     brouard  9232: /*   if (popforecast==1) { */
                   9233: /*     free_ivector(popage,0,AGESUP); */
                   9234: /*     free_vector(popeffectif,0,AGESUP); */
                   9235: /*     free_vector(popcount,0,AGESUP); */
                   9236: /*   } */
                   9237: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9238: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9239: /*   fclose(ficrespop); */
                   9240: /* } /\* End of popforecast *\/ */
1.218     brouard  9241:  
1.126     brouard  9242: int fileappend(FILE *fichier, char *optionfich)
                   9243: {
                   9244:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   9245:     printf("Problem with file: %s\n", optionfich);
                   9246:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   9247:     return (0);
                   9248:   }
                   9249:   fflush(fichier);
                   9250:   return (1);
                   9251: }
                   9252: 
                   9253: 
                   9254: /**************** function prwizard **********************/
                   9255: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   9256: {
                   9257: 
                   9258:   /* Wizard to print covariance matrix template */
                   9259: 
1.164     brouard  9260:   char ca[32], cb[32];
                   9261:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  9262:   int numlinepar;
                   9263: 
                   9264:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9265:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9266:   for(i=1; i <=nlstate; i++){
                   9267:     jj=0;
                   9268:     for(j=1; j <=nlstate+ndeath; j++){
                   9269:       if(j==i) continue;
                   9270:       jj++;
                   9271:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   9272:       printf("%1d%1d",i,j);
                   9273:       fprintf(ficparo,"%1d%1d",i,j);
                   9274:       for(k=1; k<=ncovmodel;k++){
                   9275:        /*        printf(" %lf",param[i][j][k]); */
                   9276:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   9277:        printf(" 0.");
                   9278:        fprintf(ficparo," 0.");
                   9279:       }
                   9280:       printf("\n");
                   9281:       fprintf(ficparo,"\n");
                   9282:     }
                   9283:   }
                   9284:   printf("# Scales (for hessian or gradient estimation)\n");
                   9285:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   9286:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   9287:   for(i=1; i <=nlstate; i++){
                   9288:     jj=0;
                   9289:     for(j=1; j <=nlstate+ndeath; j++){
                   9290:       if(j==i) continue;
                   9291:       jj++;
                   9292:       fprintf(ficparo,"%1d%1d",i,j);
                   9293:       printf("%1d%1d",i,j);
                   9294:       fflush(stdout);
                   9295:       for(k=1; k<=ncovmodel;k++){
                   9296:        /*      printf(" %le",delti3[i][j][k]); */
                   9297:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   9298:        printf(" 0.");
                   9299:        fprintf(ficparo," 0.");
                   9300:       }
                   9301:       numlinepar++;
                   9302:       printf("\n");
                   9303:       fprintf(ficparo,"\n");
                   9304:     }
                   9305:   }
                   9306:   printf("# Covariance matrix\n");
                   9307: /* # 121 Var(a12)\n\ */
                   9308: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9309: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   9310: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   9311: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   9312: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   9313: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   9314: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   9315:   fflush(stdout);
                   9316:   fprintf(ficparo,"# Covariance matrix\n");
                   9317:   /* # 121 Var(a12)\n\ */
                   9318:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9319:   /* #   ...\n\ */
                   9320:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   9321:   
                   9322:   for(itimes=1;itimes<=2;itimes++){
                   9323:     jj=0;
                   9324:     for(i=1; i <=nlstate; i++){
                   9325:       for(j=1; j <=nlstate+ndeath; j++){
                   9326:        if(j==i) continue;
                   9327:        for(k=1; k<=ncovmodel;k++){
                   9328:          jj++;
                   9329:          ca[0]= k+'a'-1;ca[1]='\0';
                   9330:          if(itimes==1){
                   9331:            printf("#%1d%1d%d",i,j,k);
                   9332:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   9333:          }else{
                   9334:            printf("%1d%1d%d",i,j,k);
                   9335:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   9336:            /*  printf(" %.5le",matcov[i][j]); */
                   9337:          }
                   9338:          ll=0;
                   9339:          for(li=1;li <=nlstate; li++){
                   9340:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   9341:              if(lj==li) continue;
                   9342:              for(lk=1;lk<=ncovmodel;lk++){
                   9343:                ll++;
                   9344:                if(ll<=jj){
                   9345:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   9346:                  if(ll<jj){
                   9347:                    if(itimes==1){
                   9348:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9349:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9350:                    }else{
                   9351:                      printf(" 0.");
                   9352:                      fprintf(ficparo," 0.");
                   9353:                    }
                   9354:                  }else{
                   9355:                    if(itimes==1){
                   9356:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   9357:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   9358:                    }else{
                   9359:                      printf(" 0.");
                   9360:                      fprintf(ficparo," 0.");
                   9361:                    }
                   9362:                  }
                   9363:                }
                   9364:              } /* end lk */
                   9365:            } /* end lj */
                   9366:          } /* end li */
                   9367:          printf("\n");
                   9368:          fprintf(ficparo,"\n");
                   9369:          numlinepar++;
                   9370:        } /* end k*/
                   9371:       } /*end j */
                   9372:     } /* end i */
                   9373:   } /* end itimes */
                   9374: 
                   9375: } /* end of prwizard */
                   9376: /******************* Gompertz Likelihood ******************************/
                   9377: double gompertz(double x[])
                   9378: { 
1.302     brouard  9379:   double A=0.0,B=0.,L=0.0,sump=0.,num=0.;
1.126     brouard  9380:   int i,n=0; /* n is the size of the sample */
                   9381: 
1.220     brouard  9382:   for (i=1;i<=imx ; i++) {
1.126     brouard  9383:     sump=sump+weight[i];
                   9384:     /*    sump=sump+1;*/
                   9385:     num=num+1;
                   9386:   }
1.302     brouard  9387:   L=0.0;
                   9388:   /* agegomp=AGEGOMP; */
1.126     brouard  9389:   /* for (i=0; i<=imx; i++) 
                   9390:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9391: 
1.302     brouard  9392:   for (i=1;i<=imx ; i++) {
                   9393:     /* mu(a)=mu(agecomp)*exp(teta*(age-agegomp))
                   9394:        mu(a)=x[1]*exp(x[2]*(age-agegomp)); x[1] and x[2] are per year.
                   9395:      * L= Product mu(agedeces)exp(-\int_ageexam^agedc mu(u) du ) for a death between agedc (in month) 
                   9396:      *   and agedc +1 month, cens[i]=0: log(x[1]/YEARM)
                   9397:      * +
                   9398:      * exp(-\int_ageexam^agecens mu(u) du ) when censored, cens[i]=1
                   9399:      */
                   9400:      if (wav[i] > 1 || agedc[i] < AGESUP) {
                   9401:        if (cens[i] == 1){
                   9402:         A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   9403:        } else if (cens[i] == 0){
1.126     brouard  9404:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
1.302     brouard  9405:          +log(x[1]/YEARM) +x[2]*(agedc[i]-agegomp)+log(YEARM);
                   9406:       } else
                   9407:         printf("Gompertz cens[%d] neither 1 nor 0\n",i);
1.126     brouard  9408:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
1.302     brouard  9409:        L=L+A*weight[i];
1.126     brouard  9410:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
1.302     brouard  9411:      }
                   9412:   }
1.126     brouard  9413: 
1.302     brouard  9414:   /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
1.126     brouard  9415:  
                   9416:   return -2*L*num/sump;
                   9417: }
                   9418: 
1.136     brouard  9419: #ifdef GSL
                   9420: /******************* Gompertz_f Likelihood ******************************/
                   9421: double gompertz_f(const gsl_vector *v, void *params)
                   9422: { 
1.302     brouard  9423:   double A=0.,B=0.,LL=0.0,sump=0.,num=0.;
1.136     brouard  9424:   double *x= (double *) v->data;
                   9425:   int i,n=0; /* n is the size of the sample */
                   9426: 
                   9427:   for (i=0;i<=imx-1 ; i++) {
                   9428:     sump=sump+weight[i];
                   9429:     /*    sump=sump+1;*/
                   9430:     num=num+1;
                   9431:   }
                   9432:  
                   9433:  
                   9434:   /* for (i=0; i<=imx; i++) 
                   9435:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9436:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9437:   for (i=1;i<=imx ; i++)
                   9438:     {
                   9439:       if (cens[i] == 1 && wav[i]>1)
                   9440:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9441:       
                   9442:       if (cens[i] == 0 && wav[i]>1)
                   9443:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9444:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9445:       
                   9446:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9447:       if (wav[i] > 1 ) { /* ??? */
                   9448:        LL=LL+A*weight[i];
                   9449:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9450:       }
                   9451:     }
                   9452: 
                   9453:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9454:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9455:  
                   9456:   return -2*LL*num/sump;
                   9457: }
                   9458: #endif
                   9459: 
1.126     brouard  9460: /******************* Printing html file ***********/
1.201     brouard  9461: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9462:                  int lastpass, int stepm, int weightopt, char model[],\
                   9463:                  int imx,  double p[],double **matcov,double agemortsup){
                   9464:   int i,k;
                   9465: 
                   9466:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9467:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9468:   for (i=1;i<=2;i++) 
                   9469:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9470:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9471:   fprintf(fichtm,"</ul>");
                   9472: 
                   9473: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9474: 
                   9475:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9476: 
                   9477:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9478:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9479: 
                   9480:  
                   9481:   fflush(fichtm);
                   9482: }
                   9483: 
                   9484: /******************* Gnuplot file **************/
1.201     brouard  9485: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9486: 
                   9487:   char dirfileres[132],optfileres[132];
1.164     brouard  9488: 
1.126     brouard  9489:   int ng;
                   9490: 
                   9491: 
                   9492:   /*#ifdef windows */
                   9493:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9494:     /*#endif */
                   9495: 
                   9496: 
                   9497:   strcpy(dirfileres,optionfilefiname);
                   9498:   strcpy(optfileres,"vpl");
1.199     brouard  9499:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9500:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9501:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9502:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9503:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9504: 
                   9505: } 
                   9506: 
1.136     brouard  9507: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9508: {
1.126     brouard  9509: 
1.136     brouard  9510:   /*-------- data file ----------*/
                   9511:   FILE *fic;
                   9512:   char dummy[]="                         ";
1.240     brouard  9513:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9514:   int lstra;
1.136     brouard  9515:   int linei, month, year,iout;
1.302     brouard  9516:   int noffset=0; /* This is the offset if BOM data file */
1.136     brouard  9517:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9518:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9519:   char *stratrunc;
1.223     brouard  9520: 
1.240     brouard  9521:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9522:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9523: 
1.240     brouard  9524:   for(v=1; v <=ncovcol;v++){
                   9525:     DummyV[v]=0;
                   9526:     FixedV[v]=0;
                   9527:   }
                   9528:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9529:     DummyV[v]=1;
                   9530:     FixedV[v]=0;
                   9531:   }
                   9532:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9533:     DummyV[v]=0;
                   9534:     FixedV[v]=1;
                   9535:   }
                   9536:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9537:     DummyV[v]=1;
                   9538:     FixedV[v]=1;
                   9539:   }
                   9540:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9541:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9542:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9543:   }
1.126     brouard  9544: 
1.136     brouard  9545:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9546:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9547:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9548:   }
1.126     brouard  9549: 
1.302     brouard  9550:     /* Is it a BOM UTF-8 Windows file? */
                   9551:   /* First data line */
                   9552:   linei=0;
                   9553:   while(fgets(line, MAXLINE, fic)) {
                   9554:     noffset=0;
                   9555:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   9556:     {
                   9557:       noffset=noffset+3;
                   9558:       printf("# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);fflush(stdout);
                   9559:       fprintf(ficlog,"# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);
                   9560:       fflush(ficlog); return 1;
                   9561:     }
                   9562:     /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   9563:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
                   9564:     {
                   9565:       noffset=noffset+2;
1.304     brouard  9566:       printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9567:       fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9568:       fflush(ficlog); return 1;
                   9569:     }
                   9570:     else if( line[0] == 0 && line[1] == 0)
                   9571:     {
                   9572:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   9573:        noffset=noffset+4;
1.304     brouard  9574:        printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9575:        fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9576:        fflush(ficlog); return 1;
                   9577:       }
                   9578:     } else{
                   9579:       ;/*printf(" Not a BOM file\n");*/
                   9580:     }
                   9581:         /* If line starts with a # it is a comment */
                   9582:     if (line[noffset] == '#') {
                   9583:       linei=linei+1;
                   9584:       break;
                   9585:     }else{
                   9586:       break;
                   9587:     }
                   9588:   }
                   9589:   fclose(fic);
                   9590:   if((fic=fopen(datafile,"r"))==NULL)    {
                   9591:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9592:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
                   9593:   }
                   9594:   /* Not a Bom file */
                   9595:   
1.136     brouard  9596:   i=1;
                   9597:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9598:     linei=linei+1;
                   9599:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9600:       if(line[j] == '\t')
                   9601:        line[j] = ' ';
                   9602:     }
                   9603:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9604:       ;
                   9605:     };
                   9606:     line[j+1]=0;  /* Trims blanks at end of line */
                   9607:     if(line[0]=='#'){
                   9608:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9609:       printf("Comment line\n%s\n",line);
                   9610:       continue;
                   9611:     }
                   9612:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9613:     strcpy(line, linetmp);
1.223     brouard  9614:     
                   9615:     /* Loops on waves */
                   9616:     for (j=maxwav;j>=1;j--){
                   9617:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9618:        cutv(stra, strb, line, ' '); 
                   9619:        if(strb[0]=='.') { /* Missing value */
                   9620:          lval=-1;
                   9621:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9622:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9623:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9624:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9625:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9626:            return 1;
                   9627:          }
                   9628:        }else{
                   9629:          errno=0;
                   9630:          /* what_kind_of_number(strb); */
                   9631:          dval=strtod(strb,&endptr); 
                   9632:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9633:          /* if(strb != endptr && *endptr == '\0') */
                   9634:          /*    dval=dlval; */
                   9635:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9636:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9637:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9638:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9639:            return 1;
                   9640:          }
                   9641:          cotqvar[j][iv][i]=dval; 
                   9642:          cotvar[j][ntv+iv][i]=dval; 
                   9643:        }
                   9644:        strcpy(line,stra);
1.223     brouard  9645:       }/* end loop ntqv */
1.225     brouard  9646:       
1.223     brouard  9647:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9648:        cutv(stra, strb, line, ' '); 
                   9649:        if(strb[0]=='.') { /* Missing value */
                   9650:          lval=-1;
                   9651:        }else{
                   9652:          errno=0;
                   9653:          lval=strtol(strb,&endptr,10); 
                   9654:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9655:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9656:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9657:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9658:            return 1;
                   9659:          }
                   9660:        }
                   9661:        if(lval <-1 || lval >1){
                   9662:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.319   ! brouard  9663:  Should be a value of %d(nth) covariate of wave %d (0 should be the value for the reference and 1\n \
1.223     brouard  9664:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9665:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9666:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9667:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9668:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9669:  output of IMaCh is often meaningless.\n                               \
1.319   ! brouard  9670:  Exiting.\n",lval,linei, i,line,iv,j);
1.238     brouard  9671:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.319   ! brouard  9672:  Should be a value of %d(nth) covariate of wave %d (0 should be the value for the reference and 1\n \
1.223     brouard  9673:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9674:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9675:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9676:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9677:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9678:  output of IMaCh is often meaningless.\n                               \
1.319   ! brouard  9679:  Exiting.\n",lval,linei, i,line,iv,j);fflush(ficlog);
1.238     brouard  9680:          return 1;
                   9681:        }
                   9682:        cotvar[j][iv][i]=(double)(lval);
                   9683:        strcpy(line,stra);
1.223     brouard  9684:       }/* end loop ntv */
1.225     brouard  9685:       
1.223     brouard  9686:       /* Statuses  at wave */
1.137     brouard  9687:       cutv(stra, strb, line, ' '); 
1.223     brouard  9688:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9689:        lval=-1;
1.136     brouard  9690:       }else{
1.238     brouard  9691:        errno=0;
                   9692:        lval=strtol(strb,&endptr,10); 
                   9693:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9694:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9695:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9696:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9697:          return 1;
                   9698:        }
1.136     brouard  9699:       }
1.225     brouard  9700:       
1.136     brouard  9701:       s[j][i]=lval;
1.225     brouard  9702:       
1.223     brouard  9703:       /* Date of Interview */
1.136     brouard  9704:       strcpy(line,stra);
                   9705:       cutv(stra, strb,line,' ');
1.169     brouard  9706:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9707:       }
1.169     brouard  9708:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9709:        month=99;
                   9710:        year=9999;
1.136     brouard  9711:       }else{
1.225     brouard  9712:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9713:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9714:        return 1;
1.136     brouard  9715:       }
                   9716:       anint[j][i]= (double) year; 
1.302     brouard  9717:       mint[j][i]= (double)month;
                   9718:       /* if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){ */
                   9719:       /*       printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9720:       /*       fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9721:       /* } */
1.136     brouard  9722:       strcpy(line,stra);
1.223     brouard  9723:     } /* End loop on waves */
1.225     brouard  9724:     
1.223     brouard  9725:     /* Date of death */
1.136     brouard  9726:     cutv(stra, strb,line,' '); 
1.169     brouard  9727:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9728:     }
1.169     brouard  9729:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9730:       month=99;
                   9731:       year=9999;
                   9732:     }else{
1.141     brouard  9733:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9734:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9735:       return 1;
1.136     brouard  9736:     }
                   9737:     andc[i]=(double) year; 
                   9738:     moisdc[i]=(double) month; 
                   9739:     strcpy(line,stra);
                   9740:     
1.223     brouard  9741:     /* Date of birth */
1.136     brouard  9742:     cutv(stra, strb,line,' '); 
1.169     brouard  9743:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9744:     }
1.169     brouard  9745:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9746:       month=99;
                   9747:       year=9999;
                   9748:     }else{
1.141     brouard  9749:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9750:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9751:       return 1;
1.136     brouard  9752:     }
                   9753:     if (year==9999) {
1.141     brouard  9754:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9755:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9756:       return 1;
                   9757:       
1.136     brouard  9758:     }
                   9759:     annais[i]=(double)(year);
1.302     brouard  9760:     moisnais[i]=(double)(month);
                   9761:     for (j=1;j<=maxwav;j++){
                   9762:       if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){
                   9763:        printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j,(int)moisnais[i],(int)annais[i]);
                   9764:        fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j, (int)moisnais[i],(int)annais[i]);
                   9765:       }
                   9766:     }
                   9767: 
1.136     brouard  9768:     strcpy(line,stra);
1.225     brouard  9769:     
1.223     brouard  9770:     /* Sample weight */
1.136     brouard  9771:     cutv(stra, strb,line,' '); 
                   9772:     errno=0;
                   9773:     dval=strtod(strb,&endptr); 
                   9774:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9775:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9776:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9777:       fflush(ficlog);
                   9778:       return 1;
                   9779:     }
                   9780:     weight[i]=dval; 
                   9781:     strcpy(line,stra);
1.225     brouard  9782:     
1.223     brouard  9783:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9784:       cutv(stra, strb, line, ' '); 
                   9785:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9786:        lval=-1;
1.311     brouard  9787:        coqvar[iv][i]=NAN; 
                   9788:        covar[ncovcol+iv][i]=NAN; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9789:       }else{
1.225     brouard  9790:        errno=0;
                   9791:        /* what_kind_of_number(strb); */
                   9792:        dval=strtod(strb,&endptr);
                   9793:        /* if(strb != endptr && *endptr == '\0') */
                   9794:        /*   dval=dlval; */
                   9795:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9796:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9797:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9798:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9799:          return 1;
                   9800:        }
                   9801:        coqvar[iv][i]=dval; 
1.226     brouard  9802:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9803:       }
                   9804:       strcpy(line,stra);
                   9805:     }/* end loop nqv */
1.136     brouard  9806:     
1.223     brouard  9807:     /* Covariate values */
1.136     brouard  9808:     for (j=ncovcol;j>=1;j--){
                   9809:       cutv(stra, strb,line,' '); 
1.223     brouard  9810:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9811:        lval=-1;
1.136     brouard  9812:       }else{
1.225     brouard  9813:        errno=0;
                   9814:        lval=strtol(strb,&endptr,10); 
                   9815:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9816:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9817:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9818:          return 1;
                   9819:        }
1.136     brouard  9820:       }
                   9821:       if(lval <-1 || lval >1){
1.225     brouard  9822:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9823:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9824:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9825:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9826:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9827:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9828:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9829:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9830:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9831:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9832:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9833:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9834:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9835:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9836:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9837:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9838:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9839:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9840:        return 1;
1.136     brouard  9841:       }
                   9842:       covar[j][i]=(double)(lval);
                   9843:       strcpy(line,stra);
                   9844:     }  
                   9845:     lstra=strlen(stra);
1.225     brouard  9846:     
1.136     brouard  9847:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9848:       stratrunc = &(stra[lstra-9]);
                   9849:       num[i]=atol(stratrunc);
                   9850:     }
                   9851:     else
                   9852:       num[i]=atol(stra);
                   9853:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9854:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9855:     
                   9856:     i=i+1;
                   9857:   } /* End loop reading  data */
1.225     brouard  9858:   
1.136     brouard  9859:   *imax=i-1; /* Number of individuals */
                   9860:   fclose(fic);
1.225     brouard  9861:   
1.136     brouard  9862:   return (0);
1.164     brouard  9863:   /* endread: */
1.225     brouard  9864:   printf("Exiting readdata: ");
                   9865:   fclose(fic);
                   9866:   return (1);
1.223     brouard  9867: }
1.126     brouard  9868: 
1.234     brouard  9869: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9870:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9871:   while (*p2 == ' ')
1.234     brouard  9872:     p2++; 
                   9873:   /* while ((*p1++ = *p2++) !=0) */
                   9874:   /*   ; */
                   9875:   /* do */
                   9876:   /*   while (*p2 == ' ') */
                   9877:   /*     p2++; */
                   9878:   /* while (*p1++ == *p2++); */
                   9879:   *stri=p2; 
1.145     brouard  9880: }
                   9881: 
1.235     brouard  9882: int decoderesult ( char resultline[], int nres)
1.230     brouard  9883: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9884: {
1.235     brouard  9885:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9886:   char resultsav[MAXLINE];
1.234     brouard  9887:   int resultmodel[MAXLINE];
                   9888:   int modelresult[MAXLINE];
1.230     brouard  9889:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9890: 
1.234     brouard  9891:   removefirstspace(&resultline);
1.230     brouard  9892: 
                   9893:   if (strstr(resultline,"v") !=0){
                   9894:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9895:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9896:     return 1;
                   9897:   }
                   9898:   trimbb(resultsav, resultline);
                   9899:   if (strlen(resultsav) >1){
                   9900:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9901:   }
1.253     brouard  9902:   if(j == 0){ /* Resultline but no = */
                   9903:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9904:     return (0);
                   9905:   }
1.234     brouard  9906:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
1.318     brouard  9907:     printf("ERROR: the number of variables in this result line, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
1.310     brouard  9908:     fprintf(ficlog,"ERROR: the number of variables in the resultline, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
1.234     brouard  9909:   }
                   9910:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9911:     if(nbocc(resultsav,'=') >1){
1.318     brouard  9912:       cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' (stra is the rest of the resultline to be analyzed in the next loop *//*     resultsav= "V4=1 V5=25.1 V3=0" stra= "V5=25.1 V3=0" strb= "V4=1" */
                   9913:       cutl(strc,strd,strb,'=');  /* strb:"V4=1" strc="1" strd="V4" */
1.234     brouard  9914:     }else
                   9915:       cutl(strc,strd,resultsav,'=');
1.318     brouard  9916:     Tvalsel[k]=atof(strc); /* 1 */ /* Tvalsel of k is the float value of the kth covariate appearing in this result line */
1.234     brouard  9917:     
1.230     brouard  9918:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
1.318     brouard  9919:     Tvarsel[k]=atoi(strc);  /* 4 */ /* Tvarsel is the id of the kth covariate in the result line Tvarsel[1] in "V4=1.." is 4.*/
1.230     brouard  9920:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9921:     /* cptcovsel++;     */
                   9922:     if (nbocc(stra,'=') >0)
                   9923:       strcpy(resultsav,stra); /* and analyzes it */
                   9924:   }
1.235     brouard  9925:   /* Checking for missing or useless values in comparison of current model needs */
1.318     brouard  9926:   for(k1=1; k1<= cptcovt ;k1++){ /* Loop on model. model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9927:     if(Typevar[k1]==0){ /* Single covariate in model *//*0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.234     brouard  9928:       match=0;
1.318     brouard  9929:       for(k2=1; k2 <=j;k2++){/* Loop on resultline. In result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9930:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar is coming from the model, Tvarsel from the result. Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9931:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.318     brouard  9932:          match=1; /* modelresult of k2 variable of resultline is identical to k1 variable of the model good */
1.234     brouard  9933:          break;
                   9934:        }
                   9935:       }
                   9936:       if(match == 0){
1.310     brouard  9937:        printf("Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9938:        fprintf(ficlog,"Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9939:        return 1;
1.234     brouard  9940:       }
                   9941:     }
                   9942:   }
1.235     brouard  9943:   /* Checking for missing or useless values in comparison of current model needs */
1.318     brouard  9944:   for(k2=1; k2 <=j;k2++){ /* Loop on resultline variables: result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9945:     match=0;
1.318     brouard  9946:     for(k1=1; k1<= cptcovt ;k1++){ /* loop on model: model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.235     brouard  9947:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9948:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.318     brouard  9949:          resultmodel[k1]=k2;  /* k2th variable of the model corresponds to k1 variable of the model. resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9950:          ++match;
                   9951:        }
                   9952:       }
                   9953:     }
                   9954:     if(match == 0){
                   9955:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
1.310     brouard  9956:       fprintf(ficlog,"Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9957:       return 1;
1.234     brouard  9958:     }else if(match > 1){
                   9959:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
1.310     brouard  9960:       fprintf(ficlog,"Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9961:       return 1;
1.234     brouard  9962:     }
                   9963:   }
1.235     brouard  9964:       
1.234     brouard  9965:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9966:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9967:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9968:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9969:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9970:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9971:   /*    1 0 0 0 */
                   9972:   /*    2 1 0 0 */
                   9973:   /*    3 0 1 0 */ 
                   9974:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9975:   /*    5 0 0 1 */
                   9976:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9977:   /*    7 0 1 1 */
                   9978:   /*    8 1 1 1 */
1.237     brouard  9979:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9980:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9981:   /* V5*age V5 known which value for nres?  */
                   9982:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.318     brouard  9983:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* loop on model line */
1.235     brouard  9984:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9985:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9986:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9987:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9988:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9989:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9990:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9991:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9992:       k4++;;
                   9993:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
1.318     brouard  9994:       k3q= resultmodel[k1]; /* resultmodel[1(V5)] = 25.1=k3q */
                   9995:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[1]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9996:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9997:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9998:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9999:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   10000:       k4q++;;
                   10001:     }
                   10002:   }
1.234     brouard  10003:   
1.235     brouard  10004:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  10005:   return (0);
                   10006: }
1.235     brouard  10007: 
1.230     brouard  10008: int decodemodel( char model[], int lastobs)
                   10009:  /**< This routine decodes the model and returns:
1.224     brouard  10010:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   10011:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   10012:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   10013:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   10014:        * - cptcovage number of covariates with age*products =2
                   10015:        * - cptcovs number of simple covariates
                   10016:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   10017:        *     which is a new column after the 9 (ncovcol) variables. 
1.319   ! brouard  10018:        * - if k is a product Vn*Vm, covar[k][i] is filled with correct values for each individual
1.224     brouard  10019:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   10020:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   10021:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   10022:        */
1.319   ! brouard  10023: /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1, Tage[1]=2 */
1.136     brouard  10024: {
1.238     brouard  10025:   int i, j, k, ks, v;
1.227     brouard  10026:   int  j1, k1, k2, k3, k4;
1.136     brouard  10027:   char modelsav[80];
1.145     brouard  10028:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  10029:   char *strpt;
1.136     brouard  10030: 
1.145     brouard  10031:   /*removespace(model);*/
1.136     brouard  10032:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  10033:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  10034:     if (strstr(model,"AGE") !=0){
1.192     brouard  10035:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   10036:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  10037:       return 1;
                   10038:     }
1.141     brouard  10039:     if (strstr(model,"v") !=0){
                   10040:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   10041:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   10042:       return 1;
                   10043:     }
1.187     brouard  10044:     strcpy(modelsav,model); 
                   10045:     if ((strpt=strstr(model,"age*age")) !=0){
                   10046:       printf(" strpt=%s, model=%s\n",strpt, model);
                   10047:       if(strpt != model){
1.234     brouard  10048:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  10049:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  10050:  corresponding column of parameters.\n",model);
1.234     brouard  10051:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  10052:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  10053:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  10054:        return 1;
1.225     brouard  10055:       }
1.187     brouard  10056:       nagesqr=1;
                   10057:       if (strstr(model,"+age*age") !=0)
1.234     brouard  10058:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  10059:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  10060:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  10061:       else 
1.234     brouard  10062:        substrchaine(modelsav, model, "age*age");
1.187     brouard  10063:     }else
                   10064:       nagesqr=0;
                   10065:     if (strlen(modelsav) >1){
                   10066:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   10067:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  10068:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  10069:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  10070:                     * cst, age and age*age 
                   10071:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   10072:       /* including age products which are counted in cptcovage.
                   10073:        * but the covariates which are products must be treated 
                   10074:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  10075:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   10076:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  10077:       
                   10078:       
1.187     brouard  10079:       /*   Design
                   10080:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   10081:        *  <          ncovcol=8                >
                   10082:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   10083:        *   k=  1    2      3       4     5       6      7        8
                   10084:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   10085:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  10086:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   10087:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  10088:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   10089:        *  Tage[++cptcovage]=k
                   10090:        *       if products, new covar are created after ncovcol with k1
                   10091:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   10092:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   10093:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   10094:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   10095:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   10096:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   10097:        *  <          ncovcol=8                >
                   10098:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   10099:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   10100:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
1.319   ! brouard  10101:        * p Tvar[1]@12={2,   1,     3,      3,  11,     10,     8,       8,   7,   8,   5,  6}
1.187     brouard  10102:        * p Tprod[1]@2={                         6, 5}
                   10103:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   10104:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   10105:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
1.319   ! brouard  10106:        *How to reorganize? Tvars(orted)
1.187     brouard  10107:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   10108:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   10109:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   10110:        * Struct []
                   10111:        */
1.225     brouard  10112:       
1.187     brouard  10113:       /* This loop fills the array Tvar from the string 'model'.*/
                   10114:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   10115:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   10116:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   10117:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   10118:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   10119:       /*       k=1 Tvar[1]=2 (from V2) */
                   10120:       /*       k=5 Tvar[5] */
                   10121:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  10122:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  10123:       /*       } */
1.198     brouard  10124:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  10125:       /*
                   10126:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  10127:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   10128:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   10129:       }
1.187     brouard  10130:       cptcovage=0;
1.319   ! brouard  10131:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model line */
        !          10132:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' cutl from left to right
        !          10133:                                         modelsav==V2+V1+V5*age+V4+V3*age strb=V3*age stra=V2+V1V5*age+V4 */    /* <model> "V5+V4+V3+V4*V3+V5*age+V1*age+V1" strb="V5" stra="V4+V3+V4*V3+V5*age+V1*age+V1" */
        !          10134:        if (nbocc(modelsav,'+')==0)
        !          10135:          strcpy(strb,modelsav); /* and analyzes it */
1.234     brouard  10136:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   10137:        /*scanf("%d",i);*/
1.319   ! brouard  10138:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V5*age+ V4+V3*age strb=V3*age */
        !          10139:          cutl(strc,strd,strb,'*'); /**< k=1 strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
1.234     brouard  10140:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   10141:            /* covar is not filled and then is empty */
                   10142:            cptcovprod--;
                   10143:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
1.319   ! brouard  10144:            Tvar[k]=atoi(stre);  /* V2+V1+V5*age+V4+V3*age Tvar[5]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
1.234     brouard  10145:            Typevar[k]=1;  /* 1 for age product */
1.319   ! brouard  10146:            cptcovage++; /* Counts the number of covariates which include age as a product */
        !          10147:            Tage[cptcovage]=k;  /*  V2+V1+V4+V3*age Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
1.234     brouard  10148:            /*printf("stre=%s ", stre);*/
                   10149:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   10150:            cptcovprod--;
                   10151:            cutl(stre,strb,strc,'V');
                   10152:            Tvar[k]=atoi(stre);
                   10153:            Typevar[k]=1;  /* 1 for age product */
                   10154:            cptcovage++;
                   10155:            Tage[cptcovage]=k;
                   10156:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   10157:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   10158:            cptcovn++;
                   10159:            cptcovprodnoage++;k1++;
                   10160:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   10161:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   10162:                                                because this model-covariate is a construction we invent a new column
                   10163:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
1.319   ! brouard  10164:                                                If already ncovcol=4 and model=V2 + V1 +V1*V4 +age*V3 +V3*V2
        !          10165:                                                thus after V4 we invent V5 and V6 because age*V3 will be computed in 4
        !          10166:                                                Tvar[3=V1*V4]=4+1=5 Tvar[5=V3*V2]=4 + 2= 6, Tvar[4=age*V3]=4 etc */
1.234     brouard  10167:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   10168:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   10169:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
1.319   ! brouard  10170:            Tposprod[k]=k1; /* Tposprod[3]=1, Tposprod[2]=5 */
1.234     brouard  10171:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   10172:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   10173:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   10174:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   10175:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  10176:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  10177:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   10178:            for (i=1; i<=lastobs;i++){
                   10179:              /* Computes the new covariate which is a product of
                   10180:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   10181:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   10182:            }
                   10183:          } /* End age is not in the model */
                   10184:        } /* End if model includes a product */
1.319   ! brouard  10185:        else { /* not a product */
1.234     brouard  10186:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   10187:          /*  scanf("%d",i);*/
                   10188:          cutl(strd,strc,strb,'V');
                   10189:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   10190:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   10191:          Tvar[k]=atoi(strd);
                   10192:          Typevar[k]=0;  /* 0 for simple covariates */
                   10193:        }
                   10194:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  10195:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  10196:                                  scanf("%d",i);*/
1.187     brouard  10197:       } /* end of loop + on total covariates */
                   10198:     } /* end if strlen(modelsave == 0) age*age might exist */
                   10199:   } /* end if strlen(model == 0) */
1.136     brouard  10200:   
                   10201:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   10202:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  10203:   
1.136     brouard  10204:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  10205:      printf("cptcovprod=%d ", cptcovprod);
                   10206:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   10207:      scanf("%d ",i);*/
                   10208: 
                   10209: 
1.230     brouard  10210: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   10211:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  10212: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   10213:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   10214:    k =           1    2   3     4       5       6      7      8        9
                   10215:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
1.319   ! brouard  10216:    Typevar[k]=   0    0   0     2       1       0      2      1        0
1.227     brouard  10217:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   10218:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   10219:          Tmodelind[combination of covar]=k;
1.225     brouard  10220: */  
                   10221: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  10222:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  10223:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  10224:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.318     brouard  10225:   printf("Model=1+age+%s\n\
1.227     brouard  10226: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   10227: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   10228: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.318     brouard  10229:   fprintf(ficlog,"Model=1+age+%s\n\
1.227     brouard  10230: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   10231: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   10232: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  10233:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  10234:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   10235:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  10236:       Fixed[k]= 0;
                   10237:       Dummy[k]= 0;
1.225     brouard  10238:       ncoveff++;
1.232     brouard  10239:       ncovf++;
1.234     brouard  10240:       nsd++;
                   10241:       modell[k].maintype= FTYPE;
                   10242:       TvarsD[nsd]=Tvar[k];
                   10243:       TvarsDind[nsd]=k;
                   10244:       TvarF[ncovf]=Tvar[k];
                   10245:       TvarFind[ncovf]=k;
                   10246:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10247:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10248:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   10249:       Fixed[k]= 0;
                   10250:       Dummy[k]= 0;
                   10251:       ncoveff++;
                   10252:       ncovf++;
                   10253:       modell[k].maintype= FTYPE;
                   10254:       TvarF[ncovf]=Tvar[k];
                   10255:       TvarFind[ncovf]=k;
1.230     brouard  10256:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  10257:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  10258:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  10259:       Fixed[k]= 0;
                   10260:       Dummy[k]= 1;
1.230     brouard  10261:       nqfveff++;
1.234     brouard  10262:       modell[k].maintype= FTYPE;
                   10263:       modell[k].subtype= FQ;
                   10264:       nsq++;
                   10265:       TvarsQ[nsq]=Tvar[k];
                   10266:       TvarsQind[nsq]=k;
1.232     brouard  10267:       ncovf++;
1.234     brouard  10268:       TvarF[ncovf]=Tvar[k];
                   10269:       TvarFind[ncovf]=k;
1.231     brouard  10270:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  10271:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  10272:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  10273:       Fixed[k]= 1;
                   10274:       Dummy[k]= 0;
1.225     brouard  10275:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  10276:       modell[k].maintype= VTYPE;
                   10277:       modell[k].subtype= VD;
                   10278:       nsd++;
                   10279:       TvarsD[nsd]=Tvar[k];
                   10280:       TvarsDind[nsd]=k;
                   10281:       ncovv++; /* Only simple time varying variables */
                   10282:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10283:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10284:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   10285:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  10286:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   10287:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  10288:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  10289:       Fixed[k]= 1;
                   10290:       Dummy[k]= 1;
                   10291:       nqtveff++;
                   10292:       modell[k].maintype= VTYPE;
                   10293:       modell[k].subtype= VQ;
                   10294:       ncovv++; /* Only simple time varying variables */
                   10295:       nsq++;
1.319   ! brouard  10296:       TvarsQ[nsq]=Tvar[k]; /* k=1 Tvar=5 nsq=1 TvarsQ[1]=5 */
1.234     brouard  10297:       TvarsQind[nsq]=k;
                   10298:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10299:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10300:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   10301:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  10302:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   10303:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   10304:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  10305:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  10306:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  10307:       ncova++;
                   10308:       TvarA[ncova]=Tvar[k];
                   10309:       TvarAind[ncova]=k;
1.231     brouard  10310:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  10311:        Fixed[k]= 2;
                   10312:        Dummy[k]= 2;
                   10313:        modell[k].maintype= ATYPE;
                   10314:        modell[k].subtype= APFD;
                   10315:        /* ncoveff++; */
1.227     brouard  10316:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  10317:        Fixed[k]= 2;
                   10318:        Dummy[k]= 3;
                   10319:        modell[k].maintype= ATYPE;
                   10320:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   10321:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  10322:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  10323:        Fixed[k]= 3;
                   10324:        Dummy[k]= 2;
                   10325:        modell[k].maintype= ATYPE;
                   10326:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   10327:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  10328:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10329:        Fixed[k]= 3;
                   10330:        Dummy[k]= 3;
                   10331:        modell[k].maintype= ATYPE;
                   10332:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   10333:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  10334:       }
                   10335:     }else if (Typevar[k] == 2) {  /* product without age */
                   10336:       k1=Tposprod[k];
                   10337:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  10338:        if(Tvard[k1][2] <=ncovcol){
                   10339:          Fixed[k]= 1;
                   10340:          Dummy[k]= 0;
                   10341:          modell[k].maintype= FTYPE;
                   10342:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   10343:          ncovf++; /* Fixed variables without age */
                   10344:          TvarF[ncovf]=Tvar[k];
                   10345:          TvarFind[ncovf]=k;
                   10346:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10347:          Fixed[k]= 0;  /* or 2 ?*/
                   10348:          Dummy[k]= 1;
                   10349:          modell[k].maintype= FTYPE;
                   10350:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   10351:          ncovf++; /* Varying variables without age */
                   10352:          TvarF[ncovf]=Tvar[k];
                   10353:          TvarFind[ncovf]=k;
                   10354:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10355:          Fixed[k]= 1;
                   10356:          Dummy[k]= 0;
                   10357:          modell[k].maintype= VTYPE;
                   10358:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   10359:          ncovv++; /* Varying variables without age */
                   10360:          TvarV[ncovv]=Tvar[k];
                   10361:          TvarVind[ncovv]=k;
                   10362:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10363:          Fixed[k]= 1;
                   10364:          Dummy[k]= 1;
                   10365:          modell[k].maintype= VTYPE;
                   10366:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   10367:          ncovv++; /* Varying variables without age */
                   10368:          TvarV[ncovv]=Tvar[k];
                   10369:          TvarVind[ncovv]=k;
                   10370:        }
1.227     brouard  10371:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  10372:        if(Tvard[k1][2] <=ncovcol){
                   10373:          Fixed[k]= 0;  /* or 2 ?*/
                   10374:          Dummy[k]= 1;
                   10375:          modell[k].maintype= FTYPE;
                   10376:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   10377:          ncovf++; /* Fixed variables without age */
                   10378:          TvarF[ncovf]=Tvar[k];
                   10379:          TvarFind[ncovf]=k;
                   10380:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10381:          Fixed[k]= 1;
                   10382:          Dummy[k]= 1;
                   10383:          modell[k].maintype= VTYPE;
                   10384:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   10385:          ncovv++; /* Varying variables without age */
                   10386:          TvarV[ncovv]=Tvar[k];
                   10387:          TvarVind[ncovv]=k;
                   10388:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10389:          Fixed[k]= 1;
                   10390:          Dummy[k]= 1;
                   10391:          modell[k].maintype= VTYPE;
                   10392:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   10393:          ncovv++; /* Varying variables without age */
                   10394:          TvarV[ncovv]=Tvar[k];
                   10395:          TvarVind[ncovv]=k;
                   10396:          ncovv++; /* Varying variables without age */
                   10397:          TvarV[ncovv]=Tvar[k];
                   10398:          TvarVind[ncovv]=k;
                   10399:        }
1.227     brouard  10400:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  10401:        if(Tvard[k1][2] <=ncovcol){
                   10402:          Fixed[k]= 1;
                   10403:          Dummy[k]= 1;
                   10404:          modell[k].maintype= VTYPE;
                   10405:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   10406:          ncovv++; /* Varying variables without age */
                   10407:          TvarV[ncovv]=Tvar[k];
                   10408:          TvarVind[ncovv]=k;
                   10409:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10410:          Fixed[k]= 1;
                   10411:          Dummy[k]= 1;
                   10412:          modell[k].maintype= VTYPE;
                   10413:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   10414:          ncovv++; /* Varying variables without age */
                   10415:          TvarV[ncovv]=Tvar[k];
                   10416:          TvarVind[ncovv]=k;
                   10417:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10418:          Fixed[k]= 1;
                   10419:          Dummy[k]= 0;
                   10420:          modell[k].maintype= VTYPE;
                   10421:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   10422:          ncovv++; /* Varying variables without age */
                   10423:          TvarV[ncovv]=Tvar[k];
                   10424:          TvarVind[ncovv]=k;
                   10425:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10426:          Fixed[k]= 1;
                   10427:          Dummy[k]= 1;
                   10428:          modell[k].maintype= VTYPE;
                   10429:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   10430:          ncovv++; /* Varying variables without age */
                   10431:          TvarV[ncovv]=Tvar[k];
                   10432:          TvarVind[ncovv]=k;
                   10433:        }
1.227     brouard  10434:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10435:        if(Tvard[k1][2] <=ncovcol){
                   10436:          Fixed[k]= 1;
                   10437:          Dummy[k]= 1;
                   10438:          modell[k].maintype= VTYPE;
                   10439:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   10440:          ncovv++; /* Varying variables without age */
                   10441:          TvarV[ncovv]=Tvar[k];
                   10442:          TvarVind[ncovv]=k;
                   10443:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10444:          Fixed[k]= 1;
                   10445:          Dummy[k]= 1;
                   10446:          modell[k].maintype= VTYPE;
                   10447:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   10448:          ncovv++; /* Varying variables without age */
                   10449:          TvarV[ncovv]=Tvar[k];
                   10450:          TvarVind[ncovv]=k;
                   10451:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10452:          Fixed[k]= 1;
                   10453:          Dummy[k]= 1;
                   10454:          modell[k].maintype= VTYPE;
                   10455:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   10456:          ncovv++; /* Varying variables without age */
                   10457:          TvarV[ncovv]=Tvar[k];
                   10458:          TvarVind[ncovv]=k;
                   10459:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10460:          Fixed[k]= 1;
                   10461:          Dummy[k]= 1;
                   10462:          modell[k].maintype= VTYPE;
                   10463:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10464:          ncovv++; /* Varying variables without age */
                   10465:          TvarV[ncovv]=Tvar[k];
                   10466:          TvarVind[ncovv]=k;
                   10467:        }
1.227     brouard  10468:       }else{
1.240     brouard  10469:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10470:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10471:       } /*end k1*/
1.225     brouard  10472:     }else{
1.226     brouard  10473:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10474:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10475:     }
1.227     brouard  10476:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10477:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10478:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10479:   }
                   10480:   /* Searching for doublons in the model */
                   10481:   for(k1=1; k1<= cptcovt;k1++){
                   10482:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10483:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10484:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10485:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10486:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10487:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10488:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10489:            return(1);
                   10490:          }
                   10491:        }else if (Typevar[k1] ==2){
                   10492:          k3=Tposprod[k1];
                   10493:          k4=Tposprod[k2];
                   10494:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10495:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10496:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10497:            return(1);
                   10498:          }
                   10499:        }
1.227     brouard  10500:       }
                   10501:     }
1.225     brouard  10502:   }
                   10503:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10504:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10505:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10506:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10507:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10508:   /*endread:*/
1.225     brouard  10509:   printf("Exiting decodemodel: ");
                   10510:   return (1);
1.136     brouard  10511: }
                   10512: 
1.169     brouard  10513: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10514: {/* Check ages at death */
1.136     brouard  10515:   int i, m;
1.218     brouard  10516:   int firstone=0;
                   10517:   
1.136     brouard  10518:   for (i=1; i<=imx; i++) {
                   10519:     for(m=2; (m<= maxwav); m++) {
                   10520:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10521:        anint[m][i]=9999;
1.216     brouard  10522:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10523:          s[m][i]=-1;
1.136     brouard  10524:       }
                   10525:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10526:        *nberr = *nberr + 1;
1.218     brouard  10527:        if(firstone == 0){
                   10528:          firstone=1;
1.260     brouard  10529:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10530:        }
1.262     brouard  10531:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10532:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10533:       }
                   10534:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10535:        (*nberr)++;
1.259     brouard  10536:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10537:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10538:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10539:       }
                   10540:     }
                   10541:   }
                   10542: 
                   10543:   for (i=1; i<=imx; i++)  {
                   10544:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10545:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10546:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10547:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10548:          if(agedc[i]>0){
                   10549:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10550:              agev[m][i]=agedc[i];
1.214     brouard  10551:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10552:            }else {
1.136     brouard  10553:              if ((int)andc[i]!=9999){
                   10554:                nbwarn++;
                   10555:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10556:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10557:                agev[m][i]=-1;
                   10558:              }
                   10559:            }
1.169     brouard  10560:          } /* agedc > 0 */
1.214     brouard  10561:        } /* end if */
1.136     brouard  10562:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10563:                                 years but with the precision of a month */
                   10564:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10565:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10566:            agev[m][i]=1;
                   10567:          else if(agev[m][i] < *agemin){ 
                   10568:            *agemin=agev[m][i];
                   10569:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10570:          }
                   10571:          else if(agev[m][i] >*agemax){
                   10572:            *agemax=agev[m][i];
1.156     brouard  10573:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10574:          }
                   10575:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10576:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10577:        } /* en if 9*/
1.136     brouard  10578:        else { /* =9 */
1.214     brouard  10579:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10580:          agev[m][i]=1;
                   10581:          s[m][i]=-1;
                   10582:        }
                   10583:       }
1.214     brouard  10584:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10585:        agev[m][i]=1;
1.214     brouard  10586:       else{
                   10587:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10588:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10589:        agev[m][i]=0;
                   10590:       }
                   10591:     } /* End for lastpass */
                   10592:   }
1.136     brouard  10593:     
                   10594:   for (i=1; i<=imx; i++)  {
                   10595:     for(m=firstpass; (m<=lastpass); m++){
                   10596:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10597:        (*nberr)++;
1.136     brouard  10598:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10599:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10600:        return 1;
                   10601:       }
                   10602:     }
                   10603:   }
                   10604: 
                   10605:   /*for (i=1; i<=imx; i++){
                   10606:   for (m=firstpass; (m<lastpass); m++){
                   10607:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10608: }
                   10609: 
                   10610: }*/
                   10611: 
                   10612: 
1.139     brouard  10613:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10614:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10615: 
                   10616:   return (0);
1.164     brouard  10617:  /* endread:*/
1.136     brouard  10618:     printf("Exiting calandcheckages: ");
                   10619:     return (1);
                   10620: }
                   10621: 
1.172     brouard  10622: #if defined(_MSC_VER)
                   10623: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10624: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10625: //#include "stdafx.h"
                   10626: //#include <stdio.h>
                   10627: //#include <tchar.h>
                   10628: //#include <windows.h>
                   10629: //#include <iostream>
                   10630: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10631: 
                   10632: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10633: 
                   10634: BOOL IsWow64()
                   10635: {
                   10636:        BOOL bIsWow64 = FALSE;
                   10637: 
                   10638:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10639:        //  (HANDLE, PBOOL);
                   10640: 
                   10641:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10642: 
                   10643:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10644:        const char funcName[] = "IsWow64Process";
                   10645:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10646:                GetProcAddress(module, funcName);
                   10647: 
                   10648:        if (NULL != fnIsWow64Process)
                   10649:        {
                   10650:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10651:                        &bIsWow64))
                   10652:                        //throw std::exception("Unknown error");
                   10653:                        printf("Unknown error\n");
                   10654:        }
                   10655:        return bIsWow64 != FALSE;
                   10656: }
                   10657: #endif
1.177     brouard  10658: 
1.191     brouard  10659: void syscompilerinfo(int logged)
1.292     brouard  10660: {
                   10661: #include <stdint.h>
                   10662: 
                   10663:   /* #include "syscompilerinfo.h"*/
1.185     brouard  10664:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10665:    /* /GS /W3 /Gy
                   10666:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10667:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10668:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10669:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10670:    */ 
                   10671:    /* 64 bits */
1.185     brouard  10672:    /*
                   10673:      /GS /W3 /Gy
                   10674:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10675:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10676:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10677:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10678:    /* Optimization are useless and O3 is slower than O2 */
                   10679:    /*
                   10680:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10681:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10682:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10683:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10684:    */
1.186     brouard  10685:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10686:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10687:       /PDB:"visual studio
                   10688:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10689:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10690:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10691:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10692:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10693:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10694:       uiAccess='false'"
                   10695:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10696:       /NOLOGO /TLBID:1
                   10697:    */
1.292     brouard  10698: 
                   10699: 
1.177     brouard  10700: #if defined __INTEL_COMPILER
1.178     brouard  10701: #if defined(__GNUC__)
                   10702:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10703: #endif
1.177     brouard  10704: #elif defined(__GNUC__) 
1.179     brouard  10705: #ifndef  __APPLE__
1.174     brouard  10706: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10707: #endif
1.177     brouard  10708:    struct utsname sysInfo;
1.178     brouard  10709:    int cross = CROSS;
                   10710:    if (cross){
                   10711:           printf("Cross-");
1.191     brouard  10712:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10713:    }
1.174     brouard  10714: #endif
                   10715: 
1.191     brouard  10716:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10717: #if defined(__clang__)
1.191     brouard  10718:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10719: #endif
                   10720: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10721:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10722: #endif
                   10723: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10724:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10725: #endif
                   10726: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10727:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10728: #endif
                   10729: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10730:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10731: #endif
                   10732: #if defined(_MSC_VER)
1.191     brouard  10733:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10734: #endif
                   10735: #if defined(__PGI)
1.191     brouard  10736:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10737: #endif
                   10738: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10739:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10740: #endif
1.191     brouard  10741:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10742:    
1.167     brouard  10743: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10744: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10745:     // Windows (x64 and x86)
1.191     brouard  10746:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10747: #elif __unix__ // all unices, not all compilers
                   10748:     // Unix
1.191     brouard  10749:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10750: #elif __linux__
                   10751:     // linux
1.191     brouard  10752:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10753: #elif __APPLE__
1.174     brouard  10754:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10755:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10756: #endif
                   10757: 
                   10758: /*  __MINGW32__          */
                   10759: /*  __CYGWIN__  */
                   10760: /* __MINGW64__  */
                   10761: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10762: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10763: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10764: /* _WIN64  // Defined for applications for Win64. */
                   10765: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10766: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10767: 
1.167     brouard  10768: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10769:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10770: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10771:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10772: #else
1.191     brouard  10773:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10774: #endif
                   10775: 
1.169     brouard  10776: #if defined(__GNUC__)
                   10777: # if defined(__GNUC_PATCHLEVEL__)
                   10778: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10779:                             + __GNUC_MINOR__ * 100 \
                   10780:                             + __GNUC_PATCHLEVEL__)
                   10781: # else
                   10782: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10783:                             + __GNUC_MINOR__ * 100)
                   10784: # endif
1.174     brouard  10785:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10786:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10787: 
                   10788:    if (uname(&sysInfo) != -1) {
                   10789:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10790:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10791:    }
                   10792:    else
                   10793:       perror("uname() error");
1.179     brouard  10794:    //#ifndef __INTEL_COMPILER 
                   10795: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10796:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10797:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10798: #endif
1.169     brouard  10799: #endif
1.172     brouard  10800: 
1.286     brouard  10801:    //   void main ()
1.172     brouard  10802:    //   {
1.169     brouard  10803: #if defined(_MSC_VER)
1.174     brouard  10804:    if (IsWow64()){
1.191     brouard  10805:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10806:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10807:    }
                   10808:    else{
1.191     brouard  10809:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10810:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10811:    }
1.172     brouard  10812:    //     printf("\nPress Enter to continue...");
                   10813:    //     getchar();
                   10814:    //   }
                   10815: 
1.169     brouard  10816: #endif
                   10817:    
1.167     brouard  10818: 
1.219     brouard  10819: }
1.136     brouard  10820: 
1.219     brouard  10821: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10822:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10823:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10824:   /* double ftolpl = 1.e-10; */
1.180     brouard  10825:   double age, agebase, agelim;
1.203     brouard  10826:   double tot;
1.180     brouard  10827: 
1.202     brouard  10828:   strcpy(filerespl,"PL_");
                   10829:   strcat(filerespl,fileresu);
                   10830:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10831:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10832:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10833:   }
1.288     brouard  10834:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10835:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10836:   pstamp(ficrespl);
1.288     brouard  10837:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10838:   fprintf(ficrespl,"#Age ");
                   10839:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10840:   fprintf(ficrespl,"\n");
1.180     brouard  10841:   
1.219     brouard  10842:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10843: 
1.219     brouard  10844:   agebase=ageminpar;
                   10845:   agelim=agemaxpar;
1.180     brouard  10846: 
1.227     brouard  10847:   /* i1=pow(2,ncoveff); */
1.234     brouard  10848:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10849:   if (cptcovn < 1){i1=1;}
1.180     brouard  10850: 
1.238     brouard  10851:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10852:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10853:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10854:        continue;
1.235     brouard  10855: 
1.238     brouard  10856:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10857:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10858:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10859:       /* k=k+1; */
                   10860:       /* to clean */
                   10861:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10862:       fprintf(ficrespl,"#******");
                   10863:       printf("#******");
                   10864:       fprintf(ficlog,"#******");
                   10865:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10866:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10867:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10868:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10869:       }
                   10870:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10871:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10872:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10873:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10874:       }
                   10875:       fprintf(ficrespl,"******\n");
                   10876:       printf("******\n");
                   10877:       fprintf(ficlog,"******\n");
                   10878:       if(invalidvarcomb[k]){
                   10879:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10880:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10881:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10882:        continue;
                   10883:       }
1.219     brouard  10884: 
1.238     brouard  10885:       fprintf(ficrespl,"#Age ");
                   10886:       for(j=1;j<=cptcoveff;j++) {
                   10887:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10888:       }
                   10889:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10890:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10891:     
1.238     brouard  10892:       for (age=agebase; age<=agelim; age++){
                   10893:        /* for (age=agebase; age<=agebase; age++){ */
                   10894:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10895:        fprintf(ficrespl,"%.0f ",age );
                   10896:        for(j=1;j<=cptcoveff;j++)
                   10897:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10898:        tot=0.;
                   10899:        for(i=1; i<=nlstate;i++){
                   10900:          tot +=  prlim[i][i];
                   10901:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10902:        }
                   10903:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10904:       } /* Age */
                   10905:       /* was end of cptcod */
                   10906:     } /* cptcov */
                   10907:   } /* nres */
1.219     brouard  10908:   return 0;
1.180     brouard  10909: }
                   10910: 
1.218     brouard  10911: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10912:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10913:        
                   10914:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10915:    * at any age between ageminpar and agemaxpar
                   10916:         */
1.235     brouard  10917:   int i, j, k, i1, nres=0 ;
1.217     brouard  10918:   /* double ftolpl = 1.e-10; */
                   10919:   double age, agebase, agelim;
                   10920:   double tot;
1.218     brouard  10921:   /* double ***mobaverage; */
                   10922:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10923: 
                   10924:   strcpy(fileresplb,"PLB_");
                   10925:   strcat(fileresplb,fileresu);
                   10926:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10927:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10928:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10929:   }
1.288     brouard  10930:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10931:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10932:   pstamp(ficresplb);
1.288     brouard  10933:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10934:   fprintf(ficresplb,"#Age ");
                   10935:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10936:   fprintf(ficresplb,"\n");
                   10937:   
1.218     brouard  10938:   
                   10939:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10940:   
                   10941:   agebase=ageminpar;
                   10942:   agelim=agemaxpar;
                   10943:   
                   10944:   
1.227     brouard  10945:   i1=pow(2,cptcoveff);
1.218     brouard  10946:   if (cptcovn < 1){i1=1;}
1.227     brouard  10947:   
1.238     brouard  10948:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10949:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10950:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10951:        continue;
                   10952:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10953:       fprintf(ficresplb,"#******");
                   10954:       printf("#******");
                   10955:       fprintf(ficlog,"#******");
                   10956:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10957:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10958:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10959:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10960:       }
                   10961:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10962:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10963:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10964:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10965:       }
                   10966:       fprintf(ficresplb,"******\n");
                   10967:       printf("******\n");
                   10968:       fprintf(ficlog,"******\n");
                   10969:       if(invalidvarcomb[k]){
                   10970:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10971:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10972:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10973:        continue;
                   10974:       }
1.218     brouard  10975:     
1.238     brouard  10976:       fprintf(ficresplb,"#Age ");
                   10977:       for(j=1;j<=cptcoveff;j++) {
                   10978:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10979:       }
                   10980:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10981:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10982:     
                   10983:     
1.238     brouard  10984:       for (age=agebase; age<=agelim; age++){
                   10985:        /* for (age=agebase; age<=agebase; age++){ */
                   10986:        if(mobilavproj > 0){
                   10987:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10988:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10989:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10990:        }else if (mobilavproj == 0){
                   10991:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10992:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10993:          exit(1);
                   10994:        }else{
                   10995:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10996:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10997:          /* printf("TOTOT\n"); */
                   10998:           /* exit(1); */
1.238     brouard  10999:        }
                   11000:        fprintf(ficresplb,"%.0f ",age );
                   11001:        for(j=1;j<=cptcoveff;j++)
                   11002:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11003:        tot=0.;
                   11004:        for(i=1; i<=nlstate;i++){
                   11005:          tot +=  bprlim[i][i];
                   11006:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   11007:        }
                   11008:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   11009:       } /* Age */
                   11010:       /* was end of cptcod */
1.255     brouard  11011:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  11012:     } /* end of any combination */
                   11013:   } /* end of nres */  
1.218     brouard  11014:   /* hBijx(p, bage, fage); */
                   11015:   /* fclose(ficrespijb); */
                   11016:   
                   11017:   return 0;
1.217     brouard  11018: }
1.218     brouard  11019:  
1.180     brouard  11020: int hPijx(double *p, int bage, int fage){
                   11021:     /*------------- h Pij x at various ages ------------*/
                   11022: 
                   11023:   int stepsize;
                   11024:   int agelim;
                   11025:   int hstepm;
                   11026:   int nhstepm;
1.235     brouard  11027:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  11028: 
                   11029:   double agedeb;
                   11030:   double ***p3mat;
                   11031: 
1.201     brouard  11032:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  11033:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   11034:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   11035:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   11036:     }
                   11037:     printf("Computing pij: result on file '%s' \n", filerespij);
                   11038:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   11039:   
                   11040:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   11041:     /*if (stepm<=24) stepsize=2;*/
                   11042: 
                   11043:     agelim=AGESUP;
                   11044:     hstepm=stepsize*YEARM; /* Every year of age */
                   11045:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  11046:                
1.180     brouard  11047:     /* hstepm=1;   aff par mois*/
                   11048:     pstamp(ficrespij);
                   11049:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  11050:     i1= pow(2,cptcoveff);
1.218     brouard  11051:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   11052:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   11053:                /*      k=k+1;  */
1.235     brouard  11054:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11055:     for(k=1; k<=i1;k++){
1.253     brouard  11056:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11057:        continue;
1.183     brouard  11058:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  11059:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  11060:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11061:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   11062:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   11063:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   11064:       }
1.183     brouard  11065:       fprintf(ficrespij,"******\n");
                   11066:       
                   11067:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   11068:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   11069:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   11070:        
                   11071:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  11072:        
1.183     brouard  11073:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   11074:        oldm=oldms;savm=savms;
1.235     brouard  11075:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  11076:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   11077:        for(i=1; i<=nlstate;i++)
                   11078:          for(j=1; j<=nlstate+ndeath;j++)
                   11079:            fprintf(ficrespij," %1d-%1d",i,j);
                   11080:        fprintf(ficrespij,"\n");
                   11081:        for (h=0; h<=nhstepm; h++){
                   11082:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   11083:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  11084:          for(i=1; i<=nlstate;i++)
                   11085:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  11086:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  11087:          fprintf(ficrespij,"\n");
                   11088:        }
1.183     brouard  11089:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   11090:        fprintf(ficrespij,"\n");
                   11091:       }
1.180     brouard  11092:       /*}*/
                   11093:     }
1.218     brouard  11094:     return 0;
1.180     brouard  11095: }
1.218     brouard  11096:  
                   11097:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  11098:     /*------------- h Bij x at various ages ------------*/
                   11099: 
                   11100:   int stepsize;
1.218     brouard  11101:   /* int agelim; */
                   11102:        int ageminl;
1.217     brouard  11103:   int hstepm;
                   11104:   int nhstepm;
1.238     brouard  11105:   int h, i, i1, j, k, nres;
1.218     brouard  11106:        
1.217     brouard  11107:   double agedeb;
                   11108:   double ***p3mat;
1.218     brouard  11109:        
                   11110:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   11111:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   11112:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   11113:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   11114:   }
                   11115:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   11116:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   11117:   
                   11118:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   11119:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  11120:   
1.218     brouard  11121:   /* agelim=AGESUP; */
1.289     brouard  11122:   ageminl=AGEINF; /* was 30 */
1.218     brouard  11123:   hstepm=stepsize*YEARM; /* Every year of age */
                   11124:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   11125:   
                   11126:   /* hstepm=1;   aff par mois*/
                   11127:   pstamp(ficrespijb);
1.255     brouard  11128:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  11129:   i1= pow(2,cptcoveff);
1.218     brouard  11130:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   11131:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   11132:   /*   k=k+1;  */
1.238     brouard  11133:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   11134:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11135:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  11136:        continue;
                   11137:       fprintf(ficrespijb,"\n#****** ");
                   11138:       for(j=1;j<=cptcoveff;j++)
                   11139:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11140:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11141:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11142:       }
                   11143:       fprintf(ficrespijb,"******\n");
1.264     brouard  11144:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  11145:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   11146:        continue;
                   11147:       }
                   11148:       
                   11149:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   11150:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   11151:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
1.297     brouard  11152:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm+0.1)-1; /* Typically 20 years = 20*12/6=40 or 55*12/24=27.5-1.1=>27 */
                   11153:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 or 28*/
1.238     brouard  11154:        
                   11155:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   11156:        
1.266     brouard  11157:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   11158:        /* and memory limitations if stepm is small */
                   11159: 
1.238     brouard  11160:        /* oldm=oldms;savm=savms; */
                   11161:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  11162:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  11163:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  11164:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  11165:        for(i=1; i<=nlstate;i++)
                   11166:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  11167:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  11168:        fprintf(ficrespijb,"\n");
1.238     brouard  11169:        for (h=0; h<=nhstepm; h++){
                   11170:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   11171:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   11172:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   11173:          for(i=1; i<=nlstate;i++)
                   11174:            for(j=1; j<=nlstate+ndeath;j++)
                   11175:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   11176:          fprintf(ficrespijb,"\n");
                   11177:        }
                   11178:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   11179:        fprintf(ficrespijb,"\n");
                   11180:       } /* end age deb */
                   11181:     } /* end combination */
                   11182:   } /* end nres */
1.218     brouard  11183:   return 0;
                   11184:  } /*  hBijx */
1.217     brouard  11185: 
1.180     brouard  11186: 
1.136     brouard  11187: /***********************************************/
                   11188: /**************** Main Program *****************/
                   11189: /***********************************************/
                   11190: 
                   11191: int main(int argc, char *argv[])
                   11192: {
                   11193: #ifdef GSL
                   11194:   const gsl_multimin_fminimizer_type *T;
                   11195:   size_t iteri = 0, it;
                   11196:   int rval = GSL_CONTINUE;
                   11197:   int status = GSL_SUCCESS;
                   11198:   double ssval;
                   11199: #endif
                   11200:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  11201:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   11202:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  11203:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  11204:   int jj, ll, li, lj, lk;
1.136     brouard  11205:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  11206:   int num_filled;
1.136     brouard  11207:   int itimes;
                   11208:   int NDIM=2;
                   11209:   int vpopbased=0;
1.235     brouard  11210:   int nres=0;
1.258     brouard  11211:   int endishere=0;
1.277     brouard  11212:   int noffset=0;
1.274     brouard  11213:   int ncurrv=0; /* Temporary variable */
                   11214:   
1.164     brouard  11215:   char ca[32], cb[32];
1.136     brouard  11216:   /*  FILE *fichtm; *//* Html File */
                   11217:   /* FILE *ficgp;*/ /*Gnuplot File */
                   11218:   struct stat info;
1.191     brouard  11219:   double agedeb=0.;
1.194     brouard  11220: 
                   11221:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  11222:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  11223: 
1.165     brouard  11224:   double fret;
1.191     brouard  11225:   double dum=0.; /* Dummy variable */
1.136     brouard  11226:   double ***p3mat;
1.218     brouard  11227:   /* double ***mobaverage; */
1.319   ! brouard  11228:   double wald;
1.164     brouard  11229: 
                   11230:   char line[MAXLINE];
1.197     brouard  11231:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   11232: 
1.234     brouard  11233:   char  modeltemp[MAXLINE];
1.230     brouard  11234:   char resultline[MAXLINE];
                   11235:   
1.136     brouard  11236:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  11237:   char *tok, *val; /* pathtot */
1.290     brouard  11238:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  11239:   int c,  h , cpt, c2;
1.191     brouard  11240:   int jl=0;
                   11241:   int i1, j1, jk, stepsize=0;
1.194     brouard  11242:   int count=0;
                   11243: 
1.164     brouard  11244:   int *tab; 
1.136     brouard  11245:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.296     brouard  11246:   /* double anprojd, mprojd, jprojd; /\* For eventual projections *\/ */
                   11247:   /* double anprojf, mprojf, jprojf; */
                   11248:   /* double jintmean,mintmean,aintmean;   */
                   11249:   int prvforecast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11250:   int prvbackcast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11251:   double yrfproj= 10.0; /* Number of years of forward projections */
                   11252:   double yrbproj= 10.0; /* Number of years of backward projections */
                   11253:   int prevbcast=0; /* defined as global for mlikeli and mle, replacing backcast */
1.136     brouard  11254:   int mobilav=0,popforecast=0;
1.191     brouard  11255:   int hstepm=0, nhstepm=0;
1.136     brouard  11256:   int agemortsup;
                   11257:   float  sumlpop=0.;
                   11258:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   11259:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   11260: 
1.191     brouard  11261:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  11262:   double ftolpl=FTOL;
                   11263:   double **prlim;
1.217     brouard  11264:   double **bprlim;
1.317     brouard  11265:   double ***param; /* Matrix of parameters, param[i][j][k] param=ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel) 
                   11266:                     state of origin, state of destination including death, for each covariate: constante, age, and V1 V2 etc. */
1.251     brouard  11267:   double ***paramstart; /* Matrix of starting parameter values */
                   11268:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  11269:   double **matcov; /* Matrix of covariance */
1.203     brouard  11270:   double **hess; /* Hessian matrix */
1.136     brouard  11271:   double ***delti3; /* Scale */
                   11272:   double *delti; /* Scale */
                   11273:   double ***eij, ***vareij;
                   11274:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  11275: 
1.136     brouard  11276:   double *epj, vepp;
1.164     brouard  11277: 
1.273     brouard  11278:   double dateprev1, dateprev2;
1.296     brouard  11279:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0, dateprojd=0, dateprojf=0;
                   11280:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0, datebackd=0, datebackf=0;
                   11281: 
1.217     brouard  11282: 
1.136     brouard  11283:   double **ximort;
1.145     brouard  11284:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  11285:   int *dcwave;
                   11286: 
1.164     brouard  11287:   char z[1]="c";
1.136     brouard  11288: 
                   11289:   /*char  *strt;*/
                   11290:   char strtend[80];
1.126     brouard  11291: 
1.164     brouard  11292: 
1.126     brouard  11293: /*   setlocale (LC_ALL, ""); */
                   11294: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   11295: /*   textdomain (PACKAGE); */
                   11296: /*   setlocale (LC_CTYPE, ""); */
                   11297: /*   setlocale (LC_MESSAGES, ""); */
                   11298: 
                   11299:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  11300:   rstart_time = time(NULL);  
                   11301:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   11302:   start_time = *localtime(&rstart_time);
1.126     brouard  11303:   curr_time=start_time;
1.157     brouard  11304:   /*tml = *localtime(&start_time.tm_sec);*/
                   11305:   /* strcpy(strstart,asctime(&tml)); */
                   11306:   strcpy(strstart,asctime(&start_time));
1.126     brouard  11307: 
                   11308: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  11309: /*  tp.tm_sec = tp.tm_sec +86400; */
                   11310: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  11311: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   11312: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   11313: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  11314: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  11315: /*   strt=asctime(&tmg); */
                   11316: /*   printf("Time(after) =%s",strstart);  */
                   11317: /*  (void) time (&time_value);
                   11318: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   11319: *  tm = *localtime(&time_value);
                   11320: *  strstart=asctime(&tm);
                   11321: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   11322: */
                   11323: 
                   11324:   nberr=0; /* Number of errors and warnings */
                   11325:   nbwarn=0;
1.184     brouard  11326: #ifdef WIN32
                   11327:   _getcwd(pathcd, size);
                   11328: #else
1.126     brouard  11329:   getcwd(pathcd, size);
1.184     brouard  11330: #endif
1.191     brouard  11331:   syscompilerinfo(0);
1.196     brouard  11332:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  11333:   if(argc <=1){
                   11334:     printf("\nEnter the parameter file name: ");
1.205     brouard  11335:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   11336:       printf("ERROR Empty parameter file name\n");
                   11337:       goto end;
                   11338:     }
1.126     brouard  11339:     i=strlen(pathr);
                   11340:     if(pathr[i-1]=='\n')
                   11341:       pathr[i-1]='\0';
1.156     brouard  11342:     i=strlen(pathr);
1.205     brouard  11343:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  11344:       pathr[i-1]='\0';
1.205     brouard  11345:     }
                   11346:     i=strlen(pathr);
                   11347:     if( i==0 ){
                   11348:       printf("ERROR Empty parameter file name\n");
                   11349:       goto end;
                   11350:     }
                   11351:     for (tok = pathr; tok != NULL; ){
1.126     brouard  11352:       printf("Pathr |%s|\n",pathr);
                   11353:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   11354:       printf("val= |%s| pathr=%s\n",val,pathr);
                   11355:       strcpy (pathtot, val);
                   11356:       if(pathr[0] == '\0') break; /* Dirty */
                   11357:     }
                   11358:   }
1.281     brouard  11359:   else if (argc<=2){
                   11360:     strcpy(pathtot,argv[1]);
                   11361:   }
1.126     brouard  11362:   else{
                   11363:     strcpy(pathtot,argv[1]);
1.281     brouard  11364:     strcpy(z,argv[2]);
                   11365:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  11366:   }
                   11367:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   11368:   /*cygwin_split_path(pathtot,path,optionfile);
                   11369:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   11370:   /* cutv(path,optionfile,pathtot,'\\');*/
                   11371: 
                   11372:   /* Split argv[0], imach program to get pathimach */
                   11373:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   11374:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11375:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11376:  /*   strcpy(pathimach,argv[0]); */
                   11377:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   11378:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   11379:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  11380: #ifdef WIN32
                   11381:   _chdir(path); /* Can be a relative path */
                   11382:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   11383: #else
1.126     brouard  11384:   chdir(path); /* Can be a relative path */
1.184     brouard  11385:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   11386: #endif
                   11387:   printf("Current directory %s!\n",pathcd);
1.126     brouard  11388:   strcpy(command,"mkdir ");
                   11389:   strcat(command,optionfilefiname);
                   11390:   if((outcmd=system(command)) != 0){
1.169     brouard  11391:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  11392:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   11393:     /* fclose(ficlog); */
                   11394: /*     exit(1); */
                   11395:   }
                   11396: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   11397: /*     perror("mkdir"); */
                   11398: /*   } */
                   11399: 
                   11400:   /*-------- arguments in the command line --------*/
                   11401: 
1.186     brouard  11402:   /* Main Log file */
1.126     brouard  11403:   strcat(filelog, optionfilefiname);
                   11404:   strcat(filelog,".log");    /* */
                   11405:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   11406:     printf("Problem with logfile %s\n",filelog);
                   11407:     goto end;
                   11408:   }
                   11409:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  11410:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  11411:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   11412:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   11413:  path=%s \n\
                   11414:  optionfile=%s\n\
                   11415:  optionfilext=%s\n\
1.156     brouard  11416:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  11417: 
1.197     brouard  11418:   syscompilerinfo(1);
1.167     brouard  11419: 
1.126     brouard  11420:   printf("Local time (at start):%s",strstart);
                   11421:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   11422:   fflush(ficlog);
                   11423: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  11424: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  11425: 
                   11426:   /* */
                   11427:   strcpy(fileres,"r");
                   11428:   strcat(fileres, optionfilefiname);
1.201     brouard  11429:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  11430:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  11431:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  11432: 
1.186     brouard  11433:   /* Main ---------arguments file --------*/
1.126     brouard  11434: 
                   11435:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  11436:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   11437:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  11438:     fflush(ficlog);
1.149     brouard  11439:     /* goto end; */
                   11440:     exit(70); 
1.126     brouard  11441:   }
                   11442: 
                   11443:   strcpy(filereso,"o");
1.201     brouard  11444:   strcat(filereso,fileresu);
1.126     brouard  11445:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   11446:     printf("Problem with Output resultfile: %s\n", filereso);
                   11447:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   11448:     fflush(ficlog);
                   11449:     goto end;
                   11450:   }
1.278     brouard  11451:       /*-------- Rewriting parameter file ----------*/
                   11452:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   11453:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   11454:   strcat(rfileres,".");    /* */
                   11455:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11456:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   11457:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11458:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   11459:     fflush(ficlog);
                   11460:     goto end;
                   11461:   }
                   11462:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  11463: 
1.278     brouard  11464:                                      
1.126     brouard  11465:   /* Reads comments: lines beginning with '#' */
                   11466:   numlinepar=0;
1.277     brouard  11467:   /* Is it a BOM UTF-8 Windows file? */
                   11468:   /* First parameter line */
1.197     brouard  11469:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  11470:     noffset=0;
                   11471:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   11472:     {
                   11473:       noffset=noffset+3;
                   11474:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11475:     }
1.302     brouard  11476: /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   11477:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
1.277     brouard  11478:     {
                   11479:       noffset=noffset+2;
                   11480:       printf("# File is an UTF16BE BOM file\n");
                   11481:     }
                   11482:     else if( line[0] == 0 && line[1] == 0)
                   11483:     {
                   11484:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11485:        noffset=noffset+4;
                   11486:        printf("# File is an UTF16BE BOM file\n");
                   11487:       }
                   11488:     } else{
                   11489:       ;/*printf(" Not a BOM file\n");*/
                   11490:     }
                   11491:   
1.197     brouard  11492:     /* If line starts with a # it is a comment */
1.277     brouard  11493:     if (line[noffset] == '#') {
1.197     brouard  11494:       numlinepar++;
                   11495:       fputs(line,stdout);
                   11496:       fputs(line,ficparo);
1.278     brouard  11497:       fputs(line,ficres);
1.197     brouard  11498:       fputs(line,ficlog);
                   11499:       continue;
                   11500:     }else
                   11501:       break;
                   11502:   }
                   11503:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11504:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11505:     if (num_filled != 5) {
                   11506:       printf("Should be 5 parameters\n");
1.283     brouard  11507:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11508:     }
1.126     brouard  11509:     numlinepar++;
1.197     brouard  11510:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11511:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11512:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11513:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11514:   }
                   11515:   /* Second parameter line */
                   11516:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11517:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11518:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11519:     if (line[0] == '#') {
                   11520:       numlinepar++;
1.283     brouard  11521:       printf("%s",line);
                   11522:       fprintf(ficres,"%s",line);
                   11523:       fprintf(ficparo,"%s",line);
                   11524:       fprintf(ficlog,"%s",line);
1.197     brouard  11525:       continue;
                   11526:     }else
                   11527:       break;
                   11528:   }
1.223     brouard  11529:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11530:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11531:     if (num_filled != 11) {
                   11532:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11533:       printf("but line=%s\n",line);
1.283     brouard  11534:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11535:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11536:     }
1.286     brouard  11537:     if( lastpass > maxwav){
                   11538:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11539:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11540:       fflush(ficlog);
                   11541:       goto end;
                   11542:     }
                   11543:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11544:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11545:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11546:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11547:   }
1.203     brouard  11548:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11549:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11550:   /* Third parameter line */
                   11551:   while(fgets(line, MAXLINE, ficpar)) {
                   11552:     /* If line starts with a # it is a comment */
                   11553:     if (line[0] == '#') {
                   11554:       numlinepar++;
1.283     brouard  11555:       printf("%s",line);
                   11556:       fprintf(ficres,"%s",line);
                   11557:       fprintf(ficparo,"%s",line);
                   11558:       fprintf(ficlog,"%s",line);
1.197     brouard  11559:       continue;
                   11560:     }else
                   11561:       break;
                   11562:   }
1.201     brouard  11563:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11564:     if (num_filled != 1){
1.302     brouard  11565:       printf("ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
                   11566:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
1.197     brouard  11567:       model[0]='\0';
                   11568:       goto end;
                   11569:     }
                   11570:     else{
                   11571:       if (model[0]=='+'){
                   11572:        for(i=1; i<=strlen(model);i++)
                   11573:          modeltemp[i-1]=model[i];
1.201     brouard  11574:        strcpy(model,modeltemp); 
1.197     brouard  11575:       }
                   11576:     }
1.199     brouard  11577:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11578:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11579:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11580:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11581:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11582:   }
                   11583:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11584:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11585:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11586:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11587:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11588:   fflush(ficlog);
1.190     brouard  11589:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11590:   if(model[0]=='#'){
1.279     brouard  11591:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11592:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11593:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11594:     if(mle != -1){
1.279     brouard  11595:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11596:       exit(1);
                   11597:     }
                   11598:   }
1.126     brouard  11599:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11600:     ungetc(c,ficpar);
                   11601:     fgets(line, MAXLINE, ficpar);
                   11602:     numlinepar++;
1.195     brouard  11603:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11604:       z[0]=line[1];
                   11605:     }
                   11606:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11607:     fputs(line, stdout);
                   11608:     //puts(line);
1.126     brouard  11609:     fputs(line,ficparo);
                   11610:     fputs(line,ficlog);
                   11611:   }
                   11612:   ungetc(c,ficpar);
                   11613: 
                   11614:    
1.290     brouard  11615:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11616:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11617:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11618:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11619:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11620:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11621:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11622:   */
                   11623:   if (strlen(model)>1) 
1.187     brouard  11624:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11625:   else
1.187     brouard  11626:     ncovmodel=2; /* Constant and age */
1.133     brouard  11627:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11628:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11629:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11630:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11631:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11632:     fflush(stdout);
                   11633:     fclose (ficlog);
                   11634:     goto end;
                   11635:   }
1.126     brouard  11636:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11637:   delti=delti3[1][1];
                   11638:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11639:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11640: /* We could also provide initial parameters values giving by simple logistic regression 
                   11641:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11642:       /* for(i=1;i<nlstate;i++){ */
                   11643:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11644:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11645:       /* } */
1.126     brouard  11646:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11647:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11648:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11649:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11650:     fclose (ficparo);
                   11651:     fclose (ficlog);
                   11652:     goto end;
                   11653:     exit(0);
1.220     brouard  11654:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11655:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11656:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11657:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11658:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11659:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11660:     hess=matrix(1,npar,1,npar);
1.220     brouard  11661:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11662:     /* Read guessed parameters */
1.126     brouard  11663:     /* Reads comments: lines beginning with '#' */
                   11664:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11665:       ungetc(c,ficpar);
                   11666:       fgets(line, MAXLINE, ficpar);
                   11667:       numlinepar++;
1.141     brouard  11668:       fputs(line,stdout);
1.126     brouard  11669:       fputs(line,ficparo);
                   11670:       fputs(line,ficlog);
                   11671:     }
                   11672:     ungetc(c,ficpar);
                   11673:     
                   11674:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11675:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11676:     for(i=1; i <=nlstate; i++){
1.234     brouard  11677:       j=0;
1.126     brouard  11678:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11679:        if(jj==i) continue;
                   11680:        j++;
1.292     brouard  11681:        while((c=getc(ficpar))=='#' && c!= EOF){
                   11682:          ungetc(c,ficpar);
                   11683:          fgets(line, MAXLINE, ficpar);
                   11684:          numlinepar++;
                   11685:          fputs(line,stdout);
                   11686:          fputs(line,ficparo);
                   11687:          fputs(line,ficlog);
                   11688:        }
                   11689:        ungetc(c,ficpar);
1.234     brouard  11690:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11691:        if ((i1 != i) || (j1 != jj)){
                   11692:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11693: It might be a problem of design; if ncovcol and the model are correct\n \
                   11694: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11695:          exit(1);
                   11696:        }
                   11697:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11698:        if(mle==1)
                   11699:          printf("%1d%1d",i,jj);
                   11700:        fprintf(ficlog,"%1d%1d",i,jj);
                   11701:        for(k=1; k<=ncovmodel;k++){
                   11702:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11703:          if(mle==1){
                   11704:            printf(" %lf",param[i][j][k]);
                   11705:            fprintf(ficlog," %lf",param[i][j][k]);
                   11706:          }
                   11707:          else
                   11708:            fprintf(ficlog," %lf",param[i][j][k]);
                   11709:          fprintf(ficparo," %lf",param[i][j][k]);
                   11710:        }
                   11711:        fscanf(ficpar,"\n");
                   11712:        numlinepar++;
                   11713:        if(mle==1)
                   11714:          printf("\n");
                   11715:        fprintf(ficlog,"\n");
                   11716:        fprintf(ficparo,"\n");
1.126     brouard  11717:       }
                   11718:     }  
                   11719:     fflush(ficlog);
1.234     brouard  11720:     
1.251     brouard  11721:     /* Reads parameters values */
1.126     brouard  11722:     p=param[1][1];
1.251     brouard  11723:     pstart=paramstart[1][1];
1.126     brouard  11724:     
                   11725:     /* Reads comments: lines beginning with '#' */
                   11726:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11727:       ungetc(c,ficpar);
                   11728:       fgets(line, MAXLINE, ficpar);
                   11729:       numlinepar++;
1.141     brouard  11730:       fputs(line,stdout);
1.126     brouard  11731:       fputs(line,ficparo);
                   11732:       fputs(line,ficlog);
                   11733:     }
                   11734:     ungetc(c,ficpar);
                   11735: 
                   11736:     for(i=1; i <=nlstate; i++){
                   11737:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11738:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11739:        if ( (i1-i) * (j1-j) != 0){
                   11740:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11741:          exit(1);
                   11742:        }
                   11743:        printf("%1d%1d",i,j);
                   11744:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11745:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11746:        for(k=1; k<=ncovmodel;k++){
                   11747:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11748:          printf(" %le",delti3[i][j][k]);
                   11749:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11750:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11751:        }
                   11752:        fscanf(ficpar,"\n");
                   11753:        numlinepar++;
                   11754:        printf("\n");
                   11755:        fprintf(ficparo,"\n");
                   11756:        fprintf(ficlog,"\n");
1.126     brouard  11757:       }
                   11758:     }
                   11759:     fflush(ficlog);
1.234     brouard  11760:     
1.145     brouard  11761:     /* Reads covariance matrix */
1.126     brouard  11762:     delti=delti3[1][1];
1.220     brouard  11763:                
                   11764:                
1.126     brouard  11765:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11766:                
1.126     brouard  11767:     /* Reads comments: lines beginning with '#' */
                   11768:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11769:       ungetc(c,ficpar);
                   11770:       fgets(line, MAXLINE, ficpar);
                   11771:       numlinepar++;
1.141     brouard  11772:       fputs(line,stdout);
1.126     brouard  11773:       fputs(line,ficparo);
                   11774:       fputs(line,ficlog);
                   11775:     }
                   11776:     ungetc(c,ficpar);
1.220     brouard  11777:                
1.126     brouard  11778:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11779:     hess=matrix(1,npar,1,npar);
1.131     brouard  11780:     for(i=1; i <=npar; i++)
                   11781:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11782:                
1.194     brouard  11783:     /* Scans npar lines */
1.126     brouard  11784:     for(i=1; i <=npar; i++){
1.226     brouard  11785:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11786:       if(count != 3){
1.226     brouard  11787:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11788: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11789: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11790:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11791: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11792: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11793:        exit(1);
1.220     brouard  11794:       }else{
1.226     brouard  11795:        if(mle==1)
                   11796:          printf("%1d%1d%d",i1,j1,jk);
                   11797:       }
                   11798:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11799:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11800:       for(j=1; j <=i; j++){
1.226     brouard  11801:        fscanf(ficpar," %le",&matcov[i][j]);
                   11802:        if(mle==1){
                   11803:          printf(" %.5le",matcov[i][j]);
                   11804:        }
                   11805:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11806:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11807:       }
                   11808:       fscanf(ficpar,"\n");
                   11809:       numlinepar++;
                   11810:       if(mle==1)
1.220     brouard  11811:                                printf("\n");
1.126     brouard  11812:       fprintf(ficlog,"\n");
                   11813:       fprintf(ficparo,"\n");
                   11814:     }
1.194     brouard  11815:     /* End of read covariance matrix npar lines */
1.126     brouard  11816:     for(i=1; i <=npar; i++)
                   11817:       for(j=i+1;j<=npar;j++)
1.226     brouard  11818:        matcov[i][j]=matcov[j][i];
1.126     brouard  11819:     
                   11820:     if(mle==1)
                   11821:       printf("\n");
                   11822:     fprintf(ficlog,"\n");
                   11823:     
                   11824:     fflush(ficlog);
                   11825:     
                   11826:   }    /* End of mle != -3 */
1.218     brouard  11827:   
1.186     brouard  11828:   /*  Main data
                   11829:    */
1.290     brouard  11830:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11831:   /* num=lvector(1,n); */
                   11832:   /* moisnais=vector(1,n); */
                   11833:   /* annais=vector(1,n); */
                   11834:   /* moisdc=vector(1,n); */
                   11835:   /* andc=vector(1,n); */
                   11836:   /* weight=vector(1,n); */
                   11837:   /* agedc=vector(1,n); */
                   11838:   /* cod=ivector(1,n); */
                   11839:   /* for(i=1;i<=n;i++){ */
                   11840:   num=lvector(firstobs,lastobs);
                   11841:   moisnais=vector(firstobs,lastobs);
                   11842:   annais=vector(firstobs,lastobs);
                   11843:   moisdc=vector(firstobs,lastobs);
                   11844:   andc=vector(firstobs,lastobs);
                   11845:   weight=vector(firstobs,lastobs);
                   11846:   agedc=vector(firstobs,lastobs);
                   11847:   cod=ivector(firstobs,lastobs);
                   11848:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11849:     num[i]=0;
                   11850:     moisnais[i]=0;
                   11851:     annais[i]=0;
                   11852:     moisdc[i]=0;
                   11853:     andc[i]=0;
                   11854:     agedc[i]=0;
                   11855:     cod[i]=0;
                   11856:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11857:   }
1.290     brouard  11858:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11859:   anint=matrix(1,maxwav,firstobs,lastobs);
                   11860:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11861:   tab=ivector(1,NCOVMAX);
1.144     brouard  11862:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11863:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11864: 
1.136     brouard  11865:   /* Reads data from file datafile */
                   11866:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11867:     goto end;
                   11868: 
                   11869:   /* Calculation of the number of parameters from char model */
1.234     brouard  11870:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11871:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11872:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11873:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11874:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11875:   */
                   11876:   
                   11877:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11878:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11879:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11880:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11881:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11882:   TvarF=ivector(1,NCOVMAX); /*  */
                   11883:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11884:   TvarV=ivector(1,NCOVMAX); /*  */
                   11885:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11886:   TvarA=ivector(1,NCOVMAX); /*  */
                   11887:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11888:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11889:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11890:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11891:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11892:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11893:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11894:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11895:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11896: 
1.230     brouard  11897:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11898:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11899:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11900:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11901:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11902:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11903:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11904:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11905:   */
                   11906:   /* For model-covariate k tells which data-covariate to use but
                   11907:     because this model-covariate is a construction we invent a new column
                   11908:     ncovcol + k1
                   11909:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11910:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11911:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11912:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11913:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11914:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11915:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11916:   */
1.145     brouard  11917:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11918:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11919:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11920:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11921:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11922:                         4 covariates (3 plus signs)
                   11923:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11924:                      */  
1.230     brouard  11925:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11926:                                * individual dummy, fixed or varying:
                   11927:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11928:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11929:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11930:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11931:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11932:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11933:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11934:                                * individual quantitative, fixed or varying:
                   11935:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11936:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11937:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11938: /* Main decodemodel */
                   11939: 
1.187     brouard  11940: 
1.223     brouard  11941:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11942:     goto end;
                   11943: 
1.137     brouard  11944:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11945:     nbwarn++;
                   11946:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11947:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11948:   }
1.136     brouard  11949:     /*  if(mle==1){*/
1.137     brouard  11950:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11951:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11952:   }
                   11953: 
                   11954:     /*-calculation of age at interview from date of interview and age at death -*/
                   11955:   agev=matrix(1,maxwav,1,imx);
                   11956: 
                   11957:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11958:     goto end;
                   11959: 
1.126     brouard  11960: 
1.136     brouard  11961:   agegomp=(int)agemin;
1.290     brouard  11962:   free_vector(moisnais,firstobs,lastobs);
                   11963:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11964:   /* free_matrix(mint,1,maxwav,1,n);
                   11965:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11966:   /* free_vector(moisdc,1,n); */
                   11967:   /* free_vector(andc,1,n); */
1.145     brouard  11968:   /* */
                   11969:   
1.126     brouard  11970:   wav=ivector(1,imx);
1.214     brouard  11971:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11972:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11973:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11974:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11975:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11976:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11977:    
                   11978:   /* Concatenates waves */
1.214     brouard  11979:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11980:      Death is a valid wave (if date is known).
                   11981:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11982:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11983:      and mw[mi+1][i]. dh depends on stepm.
                   11984:   */
                   11985: 
1.126     brouard  11986:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11987:   /* Concatenates waves */
1.145     brouard  11988:  
1.290     brouard  11989:   free_vector(moisdc,firstobs,lastobs);
                   11990:   free_vector(andc,firstobs,lastobs);
1.215     brouard  11991: 
1.126     brouard  11992:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11993:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11994:   ncodemax[1]=1;
1.145     brouard  11995:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11996:   cptcoveff=0;
1.220     brouard  11997:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11998:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11999:   }
                   12000:   
                   12001:   ncovcombmax=pow(2,cptcoveff);
                   12002:   invalidvarcomb=ivector(1, ncovcombmax); 
                   12003:   for(i=1;i<ncovcombmax;i++)
                   12004:     invalidvarcomb[i]=0;
                   12005:   
1.211     brouard  12006:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  12007:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  12008:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  12009:   
1.200     brouard  12010:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  12011:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  12012:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  12013:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   12014:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   12015:    * (currently 0 or 1) in the data.
                   12016:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   12017:    * corresponding modality (h,j).
                   12018:    */
                   12019: 
1.145     brouard  12020:   h=0;
                   12021:   /*if (cptcovn > 0) */
1.126     brouard  12022:   m=pow(2,cptcoveff);
                   12023:  
1.144     brouard  12024:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  12025:           * For k=4 covariates, h goes from 1 to m=2**k
                   12026:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   12027:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  12028:           *     h\k   1     2     3     4
1.143     brouard  12029:           *______________________________  
                   12030:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   12031:           *     2     2     1     1     1
                   12032:           *     3 i=2 1     2     1     1
                   12033:           *     4     2     2     1     1
                   12034:           *     5 i=3 1 i=2 1     2     1
                   12035:           *     6     2     1     2     1
                   12036:           *     7 i=4 1     2     2     1
                   12037:           *     8     2     2     2     1
1.197     brouard  12038:           *     9 i=5 1 i=3 1 i=2 1     2
                   12039:           *    10     2     1     1     2
                   12040:           *    11 i=6 1     2     1     2
                   12041:           *    12     2     2     1     2
                   12042:           *    13 i=7 1 i=4 1     2     2    
                   12043:           *    14     2     1     2     2
                   12044:           *    15 i=8 1     2     2     2
                   12045:           *    16     2     2     2     2
1.143     brouard  12046:           */
1.212     brouard  12047:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  12048:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   12049:      * and the value of each covariate?
                   12050:      * V1=1, V2=1, V3=2, V4=1 ?
                   12051:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   12052:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   12053:      * In order to get the real value in the data, we use nbcode
                   12054:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   12055:      * We are keeping this crazy system in order to be able (in the future?) 
                   12056:      * to have more than 2 values (0 or 1) for a covariate.
                   12057:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   12058:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   12059:      *              bbbbbbbb
                   12060:      *              76543210     
                   12061:      *   h-1        00000101 (6-1=5)
1.219     brouard  12062:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  12063:      *           &
                   12064:      *     1        00000001 (1)
1.219     brouard  12065:      *              00000000        = 1 & ((h-1) >> (k-1))
                   12066:      *          +1= 00000001 =1 
1.211     brouard  12067:      *
                   12068:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   12069:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   12070:      *    >>k'            11
                   12071:      *          &   00000001
                   12072:      *            = 00000001
                   12073:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   12074:      * Reverse h=6 and m=16?
                   12075:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   12076:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   12077:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   12078:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   12079:      * V3=decodtabm(14,3,2**4)=2
                   12080:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   12081:      *(h-1) >> (j-1)    0011 =13 >> 2
                   12082:      *          &1 000000001
                   12083:      *           = 000000001
                   12084:      *         +1= 000000010 =2
                   12085:      *                  2211
                   12086:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   12087:      *                  V3=2
1.220     brouard  12088:                 * codtabm and decodtabm are identical
1.211     brouard  12089:      */
                   12090: 
1.145     brouard  12091: 
                   12092:  free_ivector(Ndum,-1,NCOVMAX);
                   12093: 
                   12094: 
1.126     brouard  12095:     
1.186     brouard  12096:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  12097:   strcpy(optionfilegnuplot,optionfilefiname);
                   12098:   if(mle==-3)
1.201     brouard  12099:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  12100:   strcat(optionfilegnuplot,".gp");
                   12101: 
                   12102:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   12103:     printf("Problem with file %s",optionfilegnuplot);
                   12104:   }
                   12105:   else{
1.204     brouard  12106:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  12107:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  12108:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   12109:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  12110:   }
                   12111:   /*  fclose(ficgp);*/
1.186     brouard  12112: 
                   12113: 
                   12114:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  12115: 
                   12116:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   12117:   if(mle==-3)
1.201     brouard  12118:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  12119:   strcat(optionfilehtm,".htm");
                   12120:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  12121:     printf("Problem with %s \n",optionfilehtm);
                   12122:     exit(0);
1.126     brouard  12123:   }
                   12124: 
                   12125:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   12126:   strcat(optionfilehtmcov,"-cov.htm");
                   12127:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   12128:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   12129:   }
                   12130:   else{
                   12131:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   12132: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  12133: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  12134:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   12135:   }
                   12136: 
1.213     brouard  12137:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  12138: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   12139: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  12140: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  12141: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  12142: \n\
                   12143: <hr  size=\"2\" color=\"#EC5E5E\">\
                   12144:  <ul><li><h4>Parameter files</h4>\n\
                   12145:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   12146:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   12147:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   12148:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   12149:  - Date and time at start: %s</ul>\n",\
                   12150:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   12151:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   12152:          fileres,fileres,\
                   12153:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   12154:   fflush(fichtm);
                   12155: 
                   12156:   strcpy(pathr,path);
                   12157:   strcat(pathr,optionfilefiname);
1.184     brouard  12158: #ifdef WIN32
                   12159:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   12160: #else
1.126     brouard  12161:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  12162: #endif
                   12163:          
1.126     brouard  12164:   
1.220     brouard  12165:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   12166:                 and for any valid combination of covariates
1.126     brouard  12167:      and prints on file fileres'p'. */
1.251     brouard  12168:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  12169:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  12170: 
                   12171:   fprintf(fichtm,"\n");
1.286     brouard  12172:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  12173:          ftol, stepm);
                   12174:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   12175:   ncurrv=1;
                   12176:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   12177:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   12178:   ncurrv=i;
                   12179:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  12180:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  12181:   ncurrv=i;
                   12182:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  12183:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  12184:   ncurrv=i;
                   12185:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   12186:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   12187:           nlstate, ndeath, maxwav, mle, weightopt);
                   12188: 
                   12189:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   12190: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   12191: 
                   12192:   
1.317     brouard  12193:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Number of (used) observations=%d <br>\n\
1.126     brouard  12194: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   12195: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  12196:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  12197:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  12198:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   12199:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   12200:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   12201:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  12202: 
1.126     brouard  12203:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   12204:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   12205:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   12206: 
                   12207:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  12208:   /* For mortality only */
1.126     brouard  12209:   if (mle==-3){
1.136     brouard  12210:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  12211:     for(i=1;i<=NDIM;i++)
                   12212:       for(j=1;j<=NDIM;j++)
                   12213:        ximort[i][j]=0.;
1.186     brouard  12214:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  12215:     cens=ivector(firstobs,lastobs);
                   12216:     ageexmed=vector(firstobs,lastobs);
                   12217:     agecens=vector(firstobs,lastobs);
                   12218:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  12219:                
1.126     brouard  12220:     for (i=1; i<=imx; i++){
                   12221:       dcwave[i]=-1;
                   12222:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  12223:        if (s[m][i]>nlstate) {
                   12224:          dcwave[i]=m;
                   12225:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   12226:          break;
                   12227:        }
1.126     brouard  12228:     }
1.226     brouard  12229:     
1.126     brouard  12230:     for (i=1; i<=imx; i++) {
                   12231:       if (wav[i]>0){
1.226     brouard  12232:        ageexmed[i]=agev[mw[1][i]][i];
                   12233:        j=wav[i];
                   12234:        agecens[i]=1.; 
                   12235:        
                   12236:        if (ageexmed[i]> 1 && wav[i] > 0){
                   12237:          agecens[i]=agev[mw[j][i]][i];
                   12238:          cens[i]= 1;
                   12239:        }else if (ageexmed[i]< 1) 
                   12240:          cens[i]= -1;
                   12241:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   12242:          cens[i]=0 ;
1.126     brouard  12243:       }
                   12244:       else cens[i]=-1;
                   12245:     }
                   12246:     
                   12247:     for (i=1;i<=NDIM;i++) {
                   12248:       for (j=1;j<=NDIM;j++)
1.226     brouard  12249:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  12250:     }
                   12251:     
1.302     brouard  12252:     p[1]=0.0268; p[NDIM]=0.083;
                   12253:     /* printf("%lf %lf", p[1], p[2]); */
1.126     brouard  12254:     
                   12255:     
1.136     brouard  12256: #ifdef GSL
                   12257:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  12258: #else
1.126     brouard  12259:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  12260: #endif
1.201     brouard  12261:     strcpy(filerespow,"POW-MORT_"); 
                   12262:     strcat(filerespow,fileresu);
1.126     brouard  12263:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   12264:       printf("Problem with resultfile: %s\n", filerespow);
                   12265:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   12266:     }
1.136     brouard  12267: #ifdef GSL
                   12268:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  12269: #else
1.126     brouard  12270:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  12271: #endif
1.126     brouard  12272:     /*  for (i=1;i<=nlstate;i++)
                   12273:        for(j=1;j<=nlstate+ndeath;j++)
                   12274:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   12275:     */
                   12276:     fprintf(ficrespow,"\n");
1.136     brouard  12277: #ifdef GSL
                   12278:     /* gsl starts here */ 
                   12279:     T = gsl_multimin_fminimizer_nmsimplex;
                   12280:     gsl_multimin_fminimizer *sfm = NULL;
                   12281:     gsl_vector *ss, *x;
                   12282:     gsl_multimin_function minex_func;
                   12283: 
                   12284:     /* Initial vertex size vector */
                   12285:     ss = gsl_vector_alloc (NDIM);
                   12286:     
                   12287:     if (ss == NULL){
                   12288:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   12289:     }
                   12290:     /* Set all step sizes to 1 */
                   12291:     gsl_vector_set_all (ss, 0.001);
                   12292: 
                   12293:     /* Starting point */
1.126     brouard  12294:     
1.136     brouard  12295:     x = gsl_vector_alloc (NDIM);
                   12296:     
                   12297:     if (x == NULL){
                   12298:       gsl_vector_free(ss);
                   12299:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   12300:     }
                   12301:   
                   12302:     /* Initialize method and iterate */
                   12303:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  12304:     /*     gsl_vector_set(x, 0, 0.0268); */
                   12305:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  12306:     gsl_vector_set(x, 0, p[1]);
                   12307:     gsl_vector_set(x, 1, p[2]);
                   12308: 
                   12309:     minex_func.f = &gompertz_f;
                   12310:     minex_func.n = NDIM;
                   12311:     minex_func.params = (void *)&p; /* ??? */
                   12312:     
                   12313:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   12314:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   12315:     
                   12316:     printf("Iterations beginning .....\n\n");
                   12317:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   12318: 
                   12319:     iteri=0;
                   12320:     while (rval == GSL_CONTINUE){
                   12321:       iteri++;
                   12322:       status = gsl_multimin_fminimizer_iterate(sfm);
                   12323:       
                   12324:       if (status) printf("error: %s\n", gsl_strerror (status));
                   12325:       fflush(0);
                   12326:       
                   12327:       if (status) 
                   12328:         break;
                   12329:       
                   12330:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   12331:       ssval = gsl_multimin_fminimizer_size (sfm);
                   12332:       
                   12333:       if (rval == GSL_SUCCESS)
                   12334:         printf ("converged to a local maximum at\n");
                   12335:       
                   12336:       printf("%5d ", iteri);
                   12337:       for (it = 0; it < NDIM; it++){
                   12338:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   12339:       }
                   12340:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   12341:     }
                   12342:     
                   12343:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   12344:     
                   12345:     gsl_vector_free(x); /* initial values */
                   12346:     gsl_vector_free(ss); /* inital step size */
                   12347:     for (it=0; it<NDIM; it++){
                   12348:       p[it+1]=gsl_vector_get(sfm->x,it);
                   12349:       fprintf(ficrespow," %.12lf", p[it]);
                   12350:     }
                   12351:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   12352: #endif
                   12353: #ifdef POWELL
                   12354:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   12355: #endif  
1.126     brouard  12356:     fclose(ficrespow);
                   12357:     
1.203     brouard  12358:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  12359: 
                   12360:     for(i=1; i <=NDIM; i++)
                   12361:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  12362:                                matcov[i][j]=matcov[j][i];
1.126     brouard  12363:     
                   12364:     printf("\nCovariance matrix\n ");
1.203     brouard  12365:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  12366:     for(i=1; i <=NDIM; i++) {
                   12367:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  12368:                                printf("%f ",matcov[i][j]);
                   12369:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  12370:       }
1.203     brouard  12371:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  12372:     }
                   12373:     
                   12374:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  12375:     for (i=1;i<=NDIM;i++) {
1.126     brouard  12376:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  12377:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   12378:     }
1.302     brouard  12379:     lsurv=vector(agegomp,AGESUP);
                   12380:     lpop=vector(agegomp,AGESUP);
                   12381:     tpop=vector(agegomp,AGESUP);
1.126     brouard  12382:     lsurv[agegomp]=100000;
                   12383:     
                   12384:     for (k=agegomp;k<=AGESUP;k++) {
                   12385:       agemortsup=k;
                   12386:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   12387:     }
                   12388:     
                   12389:     for (k=agegomp;k<agemortsup;k++)
                   12390:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   12391:     
                   12392:     for (k=agegomp;k<agemortsup;k++){
                   12393:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   12394:       sumlpop=sumlpop+lpop[k];
                   12395:     }
                   12396:     
                   12397:     tpop[agegomp]=sumlpop;
                   12398:     for (k=agegomp;k<(agemortsup-3);k++){
                   12399:       /*  tpop[k+1]=2;*/
                   12400:       tpop[k+1]=tpop[k]-lpop[k];
                   12401:     }
                   12402:     
                   12403:     
                   12404:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   12405:     for (k=agegomp;k<(agemortsup-2);k++) 
                   12406:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   12407:     
                   12408:     
                   12409:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  12410:                ageminpar=50;
                   12411:                agemaxpar=100;
1.194     brouard  12412:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   12413:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12414: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12415: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   12416:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12417: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12418: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12419:     }else{
                   12420:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   12421:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  12422:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  12423:                }
1.201     brouard  12424:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  12425:                     stepm, weightopt,\
                   12426:                     model,imx,p,matcov,agemortsup);
                   12427:     
1.302     brouard  12428:     free_vector(lsurv,agegomp,AGESUP);
                   12429:     free_vector(lpop,agegomp,AGESUP);
                   12430:     free_vector(tpop,agegomp,AGESUP);
1.220     brouard  12431:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  12432:     free_ivector(dcwave,firstobs,lastobs);
                   12433:     free_vector(agecens,firstobs,lastobs);
                   12434:     free_vector(ageexmed,firstobs,lastobs);
                   12435:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  12436: #ifdef GSL
1.136     brouard  12437: #endif
1.186     brouard  12438:   } /* Endof if mle==-3 mortality only */
1.205     brouard  12439:   /* Standard  */
                   12440:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   12441:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12442:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  12443:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  12444:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12445:     for (k=1; k<=npar;k++)
                   12446:       printf(" %d %8.5f",k,p[k]);
                   12447:     printf("\n");
1.205     brouard  12448:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   12449:       /* mlikeli uses func not funcone */
1.247     brouard  12450:       /* for(i=1;i<nlstate;i++){ */
                   12451:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   12452:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   12453:       /* } */
1.205     brouard  12454:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   12455:     }
                   12456:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   12457:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12458:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   12459:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12460:     }
                   12461:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  12462:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12463:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12464:     for (k=1; k<=npar;k++)
                   12465:       printf(" %d %8.5f",k,p[k]);
                   12466:     printf("\n");
                   12467:     
                   12468:     /*--------- results files --------------*/
1.283     brouard  12469:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  12470:     
                   12471:     
                   12472:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
1.319   ! brouard  12473:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n"); /* Printing model equation */
1.126     brouard  12474:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
1.319   ! brouard  12475: 
        !          12476:     printf("#model=  1      +     age ");
        !          12477:     fprintf(ficres,"#model=  1      +     age ");
        !          12478:     fprintf(ficlog,"#model=  1      +     age ");
        !          12479:     fprintf(fichtm,"\n<ul><li> model=1+age+%s\n \
        !          12480: </ul>", model);
        !          12481: 
        !          12482:     fprintf(fichtm,"\n<table style=\"text-align:center; border: 1px solid\">\n");
        !          12483:     fprintf(fichtm, "<tr><th>Model=</th><th>1</th><th>+ age</th>");
        !          12484:     if(nagesqr==1){
        !          12485:       printf("  + age*age  ");
        !          12486:       fprintf(ficres,"  + age*age  ");
        !          12487:       fprintf(ficlog,"  + age*age  ");
        !          12488:       fprintf(fichtm, "<th>+ age*age</th>");
        !          12489:     }
        !          12490:     for(j=1;j <=ncovmodel-2;j++){
        !          12491:       if(Typevar[j]==0) {
        !          12492:        printf("  +      V%d  ",Tvar[j]);
        !          12493:        fprintf(ficres,"  +      V%d  ",Tvar[j]);
        !          12494:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
        !          12495:        fprintf(fichtm, "<th>+ V%d</th>",Tvar[j]);
        !          12496:       }else if(Typevar[j]==1) {
        !          12497:        printf("  +    V%d*age ",Tvar[j]);
        !          12498:        fprintf(ficres,"  +    V%d*age ",Tvar[j]);
        !          12499:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
        !          12500:        fprintf(fichtm, "<th>+  V%d*age</th>",Tvar[j]);
        !          12501:       }else if(Typevar[j]==2) {
        !          12502:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
        !          12503:        fprintf(ficres,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
        !          12504:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
        !          12505:        fprintf(fichtm, "<th>+  V%d*V%d</th>",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
        !          12506:       }
        !          12507:     }
        !          12508:     printf("\n");
        !          12509:     fprintf(ficres,"\n");
        !          12510:     fprintf(ficlog,"\n");
        !          12511:     fprintf(fichtm, "</tr>");
        !          12512:     fprintf(fichtm, "\n");
        !          12513:     
        !          12514:     
1.126     brouard  12515:     for(i=1,jk=1; i <=nlstate; i++){
                   12516:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  12517:        if (k != i) {
1.319   ! brouard  12518:          fprintf(fichtm, "<tr>");
1.225     brouard  12519:          printf("%d%d ",i,k);
                   12520:          fprintf(ficlog,"%d%d ",i,k);
                   12521:          fprintf(ficres,"%1d%1d ",i,k);
1.319   ! brouard  12522:          fprintf(fichtm, "<td>%1d%1d</td>",i,k);
1.225     brouard  12523:          for(j=1; j <=ncovmodel; j++){
                   12524:            printf("%12.7f ",p[jk]);
                   12525:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12526:            fprintf(ficres,"%12.7f ",p[jk]);
1.319   ! brouard  12527:            fprintf(fichtm, "<td>%12.7f</td>",p[jk]);
1.225     brouard  12528:            jk++; 
                   12529:          }
                   12530:          printf("\n");
                   12531:          fprintf(ficlog,"\n");
                   12532:          fprintf(ficres,"\n");
1.319   ! brouard  12533:          fprintf(fichtm, "</tr>\n");
1.225     brouard  12534:        }
1.126     brouard  12535:       }
                   12536:     }
1.319   ! brouard  12537:     /* fprintf(fichtm,"</tr>\n"); */
        !          12538:     fprintf(fichtm,"</table>\n");
        !          12539:     fprintf(fichtm, "\n");
        !          12540: 
1.203     brouard  12541:     if(mle != 0){
                   12542:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12543:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12544:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12545:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12546:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
1.319   ! brouard  12547:       fprintf(fichtm,"\n<table style=\"text-align:center; border: 1px solid\">");
        !          12548:       fprintf(fichtm, "\n<tr><th>Model=</th><th>1</th><th>+ age</th>");
        !          12549:       if(nagesqr==1){
        !          12550:        printf("  + age*age  ");
        !          12551:        fprintf(ficres,"  + age*age  ");
        !          12552:        fprintf(ficlog,"  + age*age  ");
        !          12553:        fprintf(fichtm, "<th>+ age*age</th>");
        !          12554:       }
        !          12555:       for(j=1;j <=ncovmodel-2;j++){
        !          12556:        if(Typevar[j]==0) {
        !          12557:          printf("  +      V%d  ",Tvar[j]);
        !          12558:          fprintf(fichtm, "<th>+ V%d</th>",Tvar[j]);
        !          12559:        }else if(Typevar[j]==1) {
        !          12560:          printf("  +    V%d*age ",Tvar[j]);
        !          12561:          fprintf(fichtm, "<th>+  V%d*age</th>",Tvar[j]);
        !          12562:        }else if(Typevar[j]==2) {
        !          12563:          fprintf(fichtm, "<th>+  V%d*V%d</th>",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
        !          12564:        }
        !          12565:       }
        !          12566:       fprintf(fichtm, "</tr>\n");
        !          12567:  
1.203     brouard  12568:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12569:        for(k=1; k <=(nlstate+ndeath); k++){
                   12570:          if (k != i) {
1.319   ! brouard  12571:            fprintf(fichtm, "<tr valign=top>");
1.225     brouard  12572:            printf("%d%d ",i,k);
                   12573:            fprintf(ficlog,"%d%d ",i,k);
1.319   ! brouard  12574:            fprintf(fichtm, "<td>%1d%1d</td>",i,k);
1.225     brouard  12575:            for(j=1; j <=ncovmodel; j++){
1.319   ! brouard  12576:              wald=p[jk]/sqrt(matcov[jk][jk]);
        !          12577:              printf("%12.7f(%12.7f) W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk],sqrt(matcov[jk][jk]), p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
        !          12578:              fprintf(ficlog,"%12.7f(%12.7f) W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk],sqrt(matcov[jk][jk]), p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
        !          12579:              if(fabs(wald) > 1.96){
        !          12580:                fprintf(fichtm, "<td><b>%12.7f</b> (%12.7f)</br>",p[jk],sqrt(matcov[jk][jk]));
        !          12581:                fprintf(fichtm,"<b>W=%8.3f</b></br>",wald);
        !          12582:              }else{
        !          12583:                fprintf(fichtm, "<td>%12.7f (%12.7f)</br>",p[jk],sqrt(matcov[jk][jk]));
        !          12584:                fprintf(fichtm,"W=%8.3f</br>",wald);
        !          12585:              }
        !          12586:              fprintf(fichtm,"[%12.7f;%12.7f]</br></td>", p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
1.225     brouard  12587:              jk++; 
                   12588:            }
                   12589:            printf("\n");
                   12590:            fprintf(ficlog,"\n");
1.319   ! brouard  12591:            fprintf(fichtm, "</tr>\n");
1.225     brouard  12592:          }
                   12593:        }
1.193     brouard  12594:       }
1.203     brouard  12595:     } /* end of hesscov and Wald tests */
1.319   ! brouard  12596:     fprintf(fichtm,"</table>\n");
1.225     brouard  12597:     
1.203     brouard  12598:     /*  */
1.126     brouard  12599:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12600:     printf("# Scales (for hessian or gradient estimation)\n");
                   12601:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12602:     for(i=1,jk=1; i <=nlstate; i++){
                   12603:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12604:        if (j!=i) {
                   12605:          fprintf(ficres,"%1d%1d",i,j);
                   12606:          printf("%1d%1d",i,j);
                   12607:          fprintf(ficlog,"%1d%1d",i,j);
                   12608:          for(k=1; k<=ncovmodel;k++){
                   12609:            printf(" %.5e",delti[jk]);
                   12610:            fprintf(ficlog," %.5e",delti[jk]);
                   12611:            fprintf(ficres," %.5e",delti[jk]);
                   12612:            jk++;
                   12613:          }
                   12614:          printf("\n");
                   12615:          fprintf(ficlog,"\n");
                   12616:          fprintf(ficres,"\n");
                   12617:        }
1.126     brouard  12618:       }
                   12619:     }
                   12620:     
                   12621:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12622:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12623:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12624:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12625:     /* # 121 Var(a12)\n\ */
                   12626:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12627:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12628:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12629:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12630:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12631:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12632:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12633:     
                   12634:     
                   12635:     /* Just to have a covariance matrix which will be more understandable
                   12636:        even is we still don't want to manage dictionary of variables
                   12637:     */
                   12638:     for(itimes=1;itimes<=2;itimes++){
                   12639:       jj=0;
                   12640:       for(i=1; i <=nlstate; i++){
1.225     brouard  12641:        for(j=1; j <=nlstate+ndeath; j++){
                   12642:          if(j==i) continue;
                   12643:          for(k=1; k<=ncovmodel;k++){
                   12644:            jj++;
                   12645:            ca[0]= k+'a'-1;ca[1]='\0';
                   12646:            if(itimes==1){
                   12647:              if(mle>=1)
                   12648:                printf("#%1d%1d%d",i,j,k);
                   12649:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12650:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12651:            }else{
                   12652:              if(mle>=1)
                   12653:                printf("%1d%1d%d",i,j,k);
                   12654:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12655:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12656:            }
                   12657:            ll=0;
                   12658:            for(li=1;li <=nlstate; li++){
                   12659:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12660:                if(lj==li) continue;
                   12661:                for(lk=1;lk<=ncovmodel;lk++){
                   12662:                  ll++;
                   12663:                  if(ll<=jj){
                   12664:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12665:                    if(ll<jj){
                   12666:                      if(itimes==1){
                   12667:                        if(mle>=1)
                   12668:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12669:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12670:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12671:                      }else{
                   12672:                        if(mle>=1)
                   12673:                          printf(" %.5e",matcov[jj][ll]); 
                   12674:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12675:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12676:                      }
                   12677:                    }else{
                   12678:                      if(itimes==1){
                   12679:                        if(mle>=1)
                   12680:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12681:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12682:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12683:                      }else{
                   12684:                        if(mle>=1)
                   12685:                          printf(" %.7e",matcov[jj][ll]); 
                   12686:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12687:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12688:                      }
                   12689:                    }
                   12690:                  }
                   12691:                } /* end lk */
                   12692:              } /* end lj */
                   12693:            } /* end li */
                   12694:            if(mle>=1)
                   12695:              printf("\n");
                   12696:            fprintf(ficlog,"\n");
                   12697:            fprintf(ficres,"\n");
                   12698:            numlinepar++;
                   12699:          } /* end k*/
                   12700:        } /*end j */
1.126     brouard  12701:       } /* end i */
                   12702:     } /* end itimes */
                   12703:     
                   12704:     fflush(ficlog);
                   12705:     fflush(ficres);
1.225     brouard  12706:     while(fgets(line, MAXLINE, ficpar)) {
                   12707:       /* If line starts with a # it is a comment */
                   12708:       if (line[0] == '#') {
                   12709:        numlinepar++;
                   12710:        fputs(line,stdout);
                   12711:        fputs(line,ficparo);
                   12712:        fputs(line,ficlog);
1.299     brouard  12713:        fputs(line,ficres);
1.225     brouard  12714:        continue;
                   12715:       }else
                   12716:        break;
                   12717:     }
                   12718:     
1.209     brouard  12719:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12720:     /*   ungetc(c,ficpar); */
                   12721:     /*   fgets(line, MAXLINE, ficpar); */
                   12722:     /*   fputs(line,stdout); */
                   12723:     /*   fputs(line,ficparo); */
                   12724:     /* } */
                   12725:     /* ungetc(c,ficpar); */
1.126     brouard  12726:     
                   12727:     estepm=0;
1.209     brouard  12728:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12729:       
                   12730:       if (num_filled != 6) {
                   12731:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12732:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12733:        goto end;
                   12734:       }
                   12735:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12736:     }
                   12737:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12738:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12739:     
1.209     brouard  12740:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12741:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12742:     if (fage <= 2) {
                   12743:       bage = ageminpar;
                   12744:       fage = agemaxpar;
                   12745:     }
                   12746:     
                   12747:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12748:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12749:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12750:                
1.186     brouard  12751:     /* Other stuffs, more or less useful */    
1.254     brouard  12752:     while(fgets(line, MAXLINE, ficpar)) {
                   12753:       /* If line starts with a # it is a comment */
                   12754:       if (line[0] == '#') {
                   12755:        numlinepar++;
                   12756:        fputs(line,stdout);
                   12757:        fputs(line,ficparo);
                   12758:        fputs(line,ficlog);
1.299     brouard  12759:        fputs(line,ficres);
1.254     brouard  12760:        continue;
                   12761:       }else
                   12762:        break;
                   12763:     }
                   12764: 
                   12765:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12766:       
                   12767:       if (num_filled != 7) {
                   12768:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12769:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12770:        goto end;
                   12771:       }
                   12772:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12773:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12774:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12775:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12776:     }
1.254     brouard  12777: 
                   12778:     while(fgets(line, MAXLINE, ficpar)) {
                   12779:       /* If line starts with a # it is a comment */
                   12780:       if (line[0] == '#') {
                   12781:        numlinepar++;
                   12782:        fputs(line,stdout);
                   12783:        fputs(line,ficparo);
                   12784:        fputs(line,ficlog);
1.299     brouard  12785:        fputs(line,ficres);
1.254     brouard  12786:        continue;
                   12787:       }else
                   12788:        break;
1.126     brouard  12789:     }
                   12790:     
                   12791:     
                   12792:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12793:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12794:     
1.254     brouard  12795:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12796:       if (num_filled != 1) {
                   12797:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12798:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12799:        goto end;
                   12800:       }
                   12801:       printf("pop_based=%d\n",popbased);
                   12802:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12803:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12804:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12805:     }
                   12806:      
1.258     brouard  12807:     /* Results */
1.307     brouard  12808:     endishere=0;
1.258     brouard  12809:     nresult=0;
1.308     brouard  12810:     parameterline=0;
1.258     brouard  12811:     do{
                   12812:       if(!fgets(line, MAXLINE, ficpar)){
                   12813:        endishere=1;
1.308     brouard  12814:        parameterline=15;
1.258     brouard  12815:       }else if (line[0] == '#') {
                   12816:        /* If line starts with a # it is a comment */
1.254     brouard  12817:        numlinepar++;
                   12818:        fputs(line,stdout);
                   12819:        fputs(line,ficparo);
                   12820:        fputs(line,ficlog);
1.299     brouard  12821:        fputs(line,ficres);
1.254     brouard  12822:        continue;
1.258     brouard  12823:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12824:        parameterline=11;
1.296     brouard  12825:       else if(sscanf(line,"prevbackcast=%[^\n]\n",modeltemp))
1.258     brouard  12826:        parameterline=12;
1.307     brouard  12827:       else if(sscanf(line,"result:%[^\n]\n",modeltemp)){
1.258     brouard  12828:        parameterline=13;
1.307     brouard  12829:       }
1.258     brouard  12830:       else{
                   12831:        parameterline=14;
1.254     brouard  12832:       }
1.308     brouard  12833:       switch (parameterline){ /* =0 only if only comments */
1.258     brouard  12834:       case 11:
1.296     brouard  12835:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12836:                  fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.258     brouard  12837:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12838:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12839:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12840:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12841:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12842:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
1.296     brouard  12843:           prvforecast = 1;
                   12844:        } 
                   12845:        else if((num_filled=sscanf(line,"prevforecast=%d yearsfproj=%lf mobil_average=%d\n",&prevfcast,&yrfproj,&mobilavproj)) !=EOF){/* && (num_filled == 3))*/
1.313     brouard  12846:          printf("prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12847:          fprintf(ficlog,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12848:          fprintf(ficres,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
1.296     brouard  12849:           prvforecast = 2;
                   12850:        }
                   12851:        else {
                   12852:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearsfproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12853:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12854:          goto end;
1.258     brouard  12855:        }
1.254     brouard  12856:        break;
1.258     brouard  12857:       case 12:
1.296     brouard  12858:        if((num_filled=sscanf(line,"prevbackcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&prevbcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12859:           fprintf(ficparo,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12860:          printf("prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12861:          fprintf(ficlog,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12862:          fprintf(ficres,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12863:          /* day and month of back2 are not used but only year anback2.*/
1.273     brouard  12864:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12865:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.296     brouard  12866:           prvbackcast = 1;
                   12867:        } 
                   12868:        else if((num_filled=sscanf(line,"prevbackcast=%d yearsbproj=%lf mobil_average=%d\n",&prevbcast,&yrbproj,&mobilavproj)) ==3){/* && (num_filled == 3))*/
1.313     brouard  12869:          printf("prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12870:          fprintf(ficlog,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12871:          fprintf(ficres,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
1.296     brouard  12872:           prvbackcast = 2;
                   12873:        }
                   12874:        else {
                   12875:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearsbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12876:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12877:          goto end;
1.258     brouard  12878:        }
1.230     brouard  12879:        break;
1.258     brouard  12880:       case 13:
1.307     brouard  12881:        num_filled=sscanf(line,"result:%[^\n]\n",resultline);
                   12882:        nresult++; /* Sum of resultlines */
                   12883:        printf("Result %d: result:%s\n",nresult, resultline);
1.318     brouard  12884:        if(nresult > MAXRESULTLINESPONE-1){
                   12885:          printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINESPONE-1,nresult,rfileres);
                   12886:          fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINESPONE-1,nresult,rfileres);
1.307     brouard  12887:          goto end;
                   12888:        }
1.310     brouard  12889:        if(!decoderesult(resultline, nresult)){ /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.314     brouard  12890:          fprintf(ficparo,"result: %s\n",resultline);
                   12891:          fprintf(ficres,"result: %s\n",resultline);
                   12892:          fprintf(ficlog,"result: %s\n",resultline);
1.310     brouard  12893:        } else
                   12894:          goto end;
1.307     brouard  12895:        break;
                   12896:       case 14:
                   12897:        printf("Error: Unknown command '%s'\n",line);
                   12898:        fprintf(ficlog,"Error: Unknown command '%s'\n",line);
1.314     brouard  12899:        if(line[0] == ' ' || line[0] == '\n'){
                   12900:          printf("It should not be an empty line '%s'\n",line);
                   12901:          fprintf(ficlog,"It should not be an empty line '%s'\n",line);
                   12902:        }         
1.307     brouard  12903:        if(ncovmodel >=2 && nresult==0 ){
                   12904:          printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
                   12905:          fprintf(ficlog,"ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12906:        }
1.307     brouard  12907:        /* goto end; */
                   12908:        break;
1.308     brouard  12909:       case 15:
                   12910:        printf("End of resultlines.\n");
                   12911:        fprintf(ficlog,"End of resultlines.\n");
                   12912:        break;
                   12913:       default: /* parameterline =0 */
1.307     brouard  12914:        nresult=1;
                   12915:        decoderesult(".",nresult ); /* No covariate */
1.258     brouard  12916:       } /* End switch parameterline */
                   12917:     }while(endishere==0); /* End do */
1.126     brouard  12918:     
1.230     brouard  12919:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12920:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12921:     
                   12922:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12923:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12924:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12925: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12926: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12927:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12928: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12929: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12930:     }else{
1.270     brouard  12931:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
1.296     brouard  12932:       /* It seems that anprojd which is computed from the mean year at interview which is known yet because of freqsummary */
                   12933:       /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */ /* Done in freqsummary */
                   12934:       if(prvforecast==1){
                   12935:         dateprojd=(jproj1+12*mproj1+365*anproj1)/365;
                   12936:         jprojd=jproj1;
                   12937:         mprojd=mproj1;
                   12938:         anprojd=anproj1;
                   12939:         dateprojf=(jproj2+12*mproj2+365*anproj2)/365;
                   12940:         jprojf=jproj2;
                   12941:         mprojf=mproj2;
                   12942:         anprojf=anproj2;
                   12943:       } else if(prvforecast == 2){
                   12944:         dateprojd=dateintmean;
                   12945:         date2dmy(dateprojd,&jprojd, &mprojd, &anprojd);
                   12946:         dateprojf=dateintmean+yrfproj;
                   12947:         date2dmy(dateprojf,&jprojf, &mprojf, &anprojf);
                   12948:       }
                   12949:       if(prvbackcast==1){
                   12950:         datebackd=(jback1+12*mback1+365*anback1)/365;
                   12951:         jbackd=jback1;
                   12952:         mbackd=mback1;
                   12953:         anbackd=anback1;
                   12954:         datebackf=(jback2+12*mback2+365*anback2)/365;
                   12955:         jbackf=jback2;
                   12956:         mbackf=mback2;
                   12957:         anbackf=anback2;
                   12958:       } else if(prvbackcast == 2){
                   12959:         datebackd=dateintmean;
                   12960:         date2dmy(datebackd,&jbackd, &mbackd, &anbackd);
                   12961:         datebackf=dateintmean-yrbproj;
                   12962:         date2dmy(datebackf,&jbackf, &mbackf, &anbackf);
                   12963:       }
                   12964:       
                   12965:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, prevbcast, pathc,p, (int)anprojd-bage, (int)anbackd-fage);
1.220     brouard  12966:     }
                   12967:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.296     brouard  12968:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,prevbcast, estepm, \
                   12969:                 jprev1,mprev1,anprev1,dateprev1, dateprojd, datebackd,jprev2,mprev2,anprev2,dateprev2,dateprojf, datebackf);
1.220     brouard  12970:                
1.225     brouard  12971:     /*------------ free_vector  -------------*/
                   12972:     /*  chdir(path); */
1.220     brouard  12973:                
1.215     brouard  12974:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12975:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12976:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12977:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  12978:     free_lvector(num,firstobs,lastobs);
                   12979:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  12980:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12981:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12982:     fclose(ficparo);
                   12983:     fclose(ficres);
1.220     brouard  12984:                
                   12985:                
1.186     brouard  12986:     /* Other results (useful)*/
1.220     brouard  12987:                
                   12988:                
1.126     brouard  12989:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12990:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12991:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12992:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12993:     fclose(ficrespl);
                   12994: 
                   12995:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12996:     /*#include "hpijx.h"*/
                   12997:     hPijx(p, bage, fage);
1.145     brouard  12998:     fclose(ficrespij);
1.227     brouard  12999:     
1.220     brouard  13000:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  13001:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  13002:     k=1;
1.126     brouard  13003:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  13004:     
1.269     brouard  13005:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   13006:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   13007:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  13008:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  13009:        for(k=1;k<=ncovcombmax;k++)
                   13010:          probs[i][j][k]=0.;
1.269     brouard  13011:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   13012:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  13013:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  13014:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   13015:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  13016:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  13017:          for(k=1;k<=ncovcombmax;k++)
                   13018:            mobaverages[i][j][k]=0.;
1.219     brouard  13019:       mobaverage=mobaverages;
                   13020:       if (mobilav!=0) {
1.235     brouard  13021:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  13022:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  13023:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   13024:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   13025:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   13026:        }
1.269     brouard  13027:       } else if (mobilavproj !=0) {
1.235     brouard  13028:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  13029:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  13030:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   13031:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   13032:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   13033:        }
1.269     brouard  13034:       }else{
                   13035:        printf("Internal error moving average\n");
                   13036:        fflush(stdout);
                   13037:        exit(1);
1.219     brouard  13038:       }
                   13039:     }/* end if moving average */
1.227     brouard  13040:     
1.126     brouard  13041:     /*---------- Forecasting ------------------*/
1.296     brouard  13042:     if(prevfcast==1){ 
                   13043:       /*   /\*    if(stepm ==1){*\/ */
                   13044:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   13045:       /*This done previously after freqsummary.*/
                   13046:       /*   dateprojd=(jproj1+12*mproj1+365*anproj1)/365; */
                   13047:       /*   dateprojf=(jproj2+12*mproj2+365*anproj2)/365; */
                   13048:       
                   13049:       /* } else if (prvforecast==2){ */
                   13050:       /*   /\*    if(stepm ==1){*\/ */
                   13051:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   13052:       /* } */
                   13053:       /*prevforecast(fileresu, dateintmean, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);*/
                   13054:       prevforecast(fileresu,dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, p, cptcoveff);
1.126     brouard  13055:     }
1.269     brouard  13056: 
1.296     brouard  13057:     /* Prevbcasting */
                   13058:     if(prevbcast==1){
1.219     brouard  13059:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   13060:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   13061:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   13062: 
                   13063:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   13064: 
                   13065:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  13066: 
1.219     brouard  13067:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   13068:       fclose(ficresplb);
                   13069: 
1.222     brouard  13070:       hBijx(p, bage, fage, mobaverage);
                   13071:       fclose(ficrespijb);
1.219     brouard  13072: 
1.296     brouard  13073:       /* /\* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, *\/ */
                   13074:       /* /\*                  mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); *\/ */
                   13075:       /* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, */
                   13076:       /*                      mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
                   13077:       prevbackforecast(fileresu, mobaverage, dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2,
                   13078:                       mobilavproj, bage, fage, firstpass, lastpass, p, cptcoveff);
                   13079: 
                   13080:       
1.269     brouard  13081:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  13082: 
                   13083:       
1.269     brouard  13084:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  13085:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   13086:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   13087:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.296     brouard  13088:     }    /* end  Prevbcasting */
1.268     brouard  13089:  
1.186     brouard  13090:  
                   13091:     /* ------ Other prevalence ratios------------ */
1.126     brouard  13092: 
1.215     brouard  13093:     free_ivector(wav,1,imx);
                   13094:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   13095:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   13096:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  13097:                
                   13098:                
1.127     brouard  13099:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  13100:                
1.201     brouard  13101:     strcpy(filerese,"E_");
                   13102:     strcat(filerese,fileresu);
1.126     brouard  13103:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   13104:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   13105:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   13106:     }
1.208     brouard  13107:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   13108:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  13109: 
                   13110:     pstamp(ficreseij);
1.219     brouard  13111:                
1.235     brouard  13112:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   13113:     if (cptcovn < 1){i1=1;}
                   13114:     
                   13115:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   13116:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  13117:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  13118:        continue;
1.219     brouard  13119:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  13120:       printf("\n#****** ");
1.225     brouard  13121:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  13122:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  13123:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13124:       }
                   13125:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13126:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13127:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  13128:       }
                   13129:       fprintf(ficreseij,"******\n");
1.235     brouard  13130:       printf("******\n");
1.219     brouard  13131:       
                   13132:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   13133:       oldm=oldms;savm=savms;
1.235     brouard  13134:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  13135:       
1.219     brouard  13136:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  13137:     }
                   13138:     fclose(ficreseij);
1.208     brouard  13139:     printf("done evsij\n");fflush(stdout);
                   13140:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  13141: 
1.218     brouard  13142:                
1.227     brouard  13143:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  13144:                
1.201     brouard  13145:     strcpy(filerest,"T_");
                   13146:     strcat(filerest,fileresu);
1.127     brouard  13147:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   13148:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   13149:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   13150:     }
1.208     brouard  13151:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   13152:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  13153:     strcpy(fileresstde,"STDE_");
                   13154:     strcat(fileresstde,fileresu);
1.126     brouard  13155:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  13156:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   13157:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  13158:     }
1.227     brouard  13159:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   13160:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  13161: 
1.201     brouard  13162:     strcpy(filerescve,"CVE_");
                   13163:     strcat(filerescve,fileresu);
1.126     brouard  13164:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  13165:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   13166:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  13167:     }
1.227     brouard  13168:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   13169:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  13170: 
1.201     brouard  13171:     strcpy(fileresv,"V_");
                   13172:     strcat(fileresv,fileresu);
1.126     brouard  13173:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   13174:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   13175:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   13176:     }
1.227     brouard  13177:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   13178:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  13179: 
1.235     brouard  13180:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   13181:     if (cptcovn < 1){i1=1;}
                   13182:     
                   13183:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   13184:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  13185:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  13186:        continue;
1.242     brouard  13187:       printf("\n#****** Result for:");
                   13188:       fprintf(ficrest,"\n#****** Result for:");
                   13189:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  13190:       for(j=1;j<=cptcoveff;j++){ 
                   13191:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13192:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13193:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13194:       }
1.235     brouard  13195:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13196:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13197:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13198:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13199:       }        
1.208     brouard  13200:       fprintf(ficrest,"******\n");
1.227     brouard  13201:       fprintf(ficlog,"******\n");
                   13202:       printf("******\n");
1.208     brouard  13203:       
                   13204:       fprintf(ficresstdeij,"\n#****** ");
                   13205:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  13206:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  13207:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13208:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  13209:       }
1.235     brouard  13210:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13211:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13212:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13213:       }        
1.208     brouard  13214:       fprintf(ficresstdeij,"******\n");
                   13215:       fprintf(ficrescveij,"******\n");
                   13216:       
                   13217:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  13218:       /* pstamp(ficresvij); */
1.225     brouard  13219:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  13220:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  13221:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13222:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13223:       }        
1.208     brouard  13224:       fprintf(ficresvij,"******\n");
                   13225:       
                   13226:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   13227:       oldm=oldms;savm=savms;
1.235     brouard  13228:       printf(" cvevsij ");
                   13229:       fprintf(ficlog, " cvevsij ");
                   13230:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  13231:       printf(" end cvevsij \n ");
                   13232:       fprintf(ficlog, " end cvevsij \n ");
                   13233:       
                   13234:       /*
                   13235:        */
                   13236:       /* goto endfree; */
                   13237:       
                   13238:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   13239:       pstamp(ficrest);
                   13240:       
1.269     brouard  13241:       epj=vector(1,nlstate+1);
1.208     brouard  13242:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  13243:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   13244:        cptcod= 0; /* To be deleted */
                   13245:        printf("varevsij vpopbased=%d \n",vpopbased);
                   13246:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  13247:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  13248:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   13249:        if(vpopbased==1)
                   13250:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   13251:        else
1.288     brouard  13252:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  13253:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   13254:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   13255:        fprintf(ficrest,"\n");
                   13256:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  13257:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   13258:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  13259:        for(age=bage; age <=fage ;age++){
1.235     brouard  13260:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  13261:          if (vpopbased==1) {
                   13262:            if(mobilav ==0){
                   13263:              for(i=1; i<=nlstate;i++)
                   13264:                prlim[i][i]=probs[(int)age][i][k];
                   13265:            }else{ /* mobilav */ 
                   13266:              for(i=1; i<=nlstate;i++)
                   13267:                prlim[i][i]=mobaverage[(int)age][i][k];
                   13268:            }
                   13269:          }
1.219     brouard  13270:          
1.227     brouard  13271:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   13272:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   13273:          /* printf(" age %4.0f ",age); */
                   13274:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   13275:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   13276:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   13277:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   13278:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   13279:            }
                   13280:            epj[nlstate+1] +=epj[j];
                   13281:          }
                   13282:          /* printf(" age %4.0f \n",age); */
1.219     brouard  13283:          
1.227     brouard  13284:          for(i=1, vepp=0.;i <=nlstate;i++)
                   13285:            for(j=1;j <=nlstate;j++)
                   13286:              vepp += vareij[i][j][(int)age];
                   13287:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   13288:          for(j=1;j <=nlstate;j++){
                   13289:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   13290:          }
                   13291:          fprintf(ficrest,"\n");
                   13292:        }
1.208     brouard  13293:       } /* End vpopbased */
1.269     brouard  13294:       free_vector(epj,1,nlstate+1);
1.208     brouard  13295:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   13296:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  13297:       printf("done selection\n");fflush(stdout);
                   13298:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  13299:       
1.235     brouard  13300:     } /* End k selection */
1.227     brouard  13301: 
                   13302:     printf("done State-specific expectancies\n");fflush(stdout);
                   13303:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   13304: 
1.288     brouard  13305:     /* variance-covariance of forward period prevalence*/
1.269     brouard  13306:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  13307: 
1.227     brouard  13308:     
1.290     brouard  13309:     free_vector(weight,firstobs,lastobs);
1.227     brouard  13310:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  13311:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   13312:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   13313:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   13314:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  13315:     free_ivector(tab,1,NCOVMAX);
                   13316:     fclose(ficresstdeij);
                   13317:     fclose(ficrescveij);
                   13318:     fclose(ficresvij);
                   13319:     fclose(ficrest);
                   13320:     fclose(ficpar);
                   13321:     
                   13322:     
1.126     brouard  13323:     /*---------- End : free ----------------*/
1.219     brouard  13324:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  13325:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   13326:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  13327:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   13328:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  13329:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  13330:   /* endfree:*/
                   13331:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   13332:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   13333:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  13334:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   13335:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   13336:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   13337:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  13338:   free_matrix(matcov,1,npar,1,npar);
                   13339:   free_matrix(hess,1,npar,1,npar);
                   13340:   /*free_vector(delti,1,npar);*/
                   13341:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   13342:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  13343:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  13344:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   13345:   
                   13346:   free_ivector(ncodemax,1,NCOVMAX);
                   13347:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   13348:   free_ivector(Dummy,-1,NCOVMAX);
                   13349:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  13350:   free_ivector(DummyV,1,NCOVMAX);
                   13351:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  13352:   free_ivector(Typevar,-1,NCOVMAX);
                   13353:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  13354:   free_ivector(TvarsQ,1,NCOVMAX);
                   13355:   free_ivector(TvarsQind,1,NCOVMAX);
                   13356:   free_ivector(TvarsD,1,NCOVMAX);
                   13357:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  13358:   free_ivector(TvarFD,1,NCOVMAX);
                   13359:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  13360:   free_ivector(TvarF,1,NCOVMAX);
                   13361:   free_ivector(TvarFind,1,NCOVMAX);
                   13362:   free_ivector(TvarV,1,NCOVMAX);
                   13363:   free_ivector(TvarVind,1,NCOVMAX);
                   13364:   free_ivector(TvarA,1,NCOVMAX);
                   13365:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  13366:   free_ivector(TvarFQ,1,NCOVMAX);
                   13367:   free_ivector(TvarFQind,1,NCOVMAX);
                   13368:   free_ivector(TvarVD,1,NCOVMAX);
                   13369:   free_ivector(TvarVDind,1,NCOVMAX);
                   13370:   free_ivector(TvarVQ,1,NCOVMAX);
                   13371:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  13372:   free_ivector(Tvarsel,1,NCOVMAX);
                   13373:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  13374:   free_ivector(Tposprod,1,NCOVMAX);
                   13375:   free_ivector(Tprod,1,NCOVMAX);
                   13376:   free_ivector(Tvaraff,1,NCOVMAX);
                   13377:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   13378:   free_ivector(Tage,1,NCOVMAX);
                   13379:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  13380:   free_ivector(TmodelInvind,1,NCOVMAX);
                   13381:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  13382:   
                   13383:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   13384:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  13385:   fflush(fichtm);
                   13386:   fflush(ficgp);
                   13387:   
1.227     brouard  13388:   
1.126     brouard  13389:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  13390:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   13391:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  13392:   }else{
                   13393:     printf("End of Imach\n");
                   13394:     fprintf(ficlog,"End of Imach\n");
                   13395:   }
                   13396:   printf("See log file on %s\n",filelog);
                   13397:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  13398:   /*(void) gettimeofday(&end_time,&tzp);*/
                   13399:   rend_time = time(NULL);  
                   13400:   end_time = *localtime(&rend_time);
                   13401:   /* tml = *localtime(&end_time.tm_sec); */
                   13402:   strcpy(strtend,asctime(&end_time));
1.126     brouard  13403:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   13404:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  13405:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  13406:   
1.157     brouard  13407:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   13408:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   13409:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  13410:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   13411: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   13412:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13413:   fclose(fichtm);
                   13414:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13415:   fclose(fichtmcov);
                   13416:   fclose(ficgp);
                   13417:   fclose(ficlog);
                   13418:   /*------ End -----------*/
1.227     brouard  13419:   
1.281     brouard  13420: 
                   13421: /* Executes gnuplot */
1.227     brouard  13422:   
                   13423:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  13424: #ifdef WIN32
1.227     brouard  13425:   if (_chdir(pathcd) != 0)
                   13426:     printf("Can't move to directory %s!\n",path);
                   13427:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  13428: #else
1.227     brouard  13429:     if(chdir(pathcd) != 0)
                   13430:       printf("Can't move to directory %s!\n", path);
                   13431:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  13432: #endif 
1.126     brouard  13433:     printf("Current directory %s!\n",pathcd);
                   13434:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   13435:   sprintf(plotcmd,"gnuplot");
1.157     brouard  13436: #ifdef _WIN32
1.126     brouard  13437:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   13438: #endif
                   13439:   if(!stat(plotcmd,&info)){
1.158     brouard  13440:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13441:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  13442:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  13443:     }else
                   13444:       strcpy(pplotcmd,plotcmd);
1.157     brouard  13445: #ifdef __unix
1.126     brouard  13446:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   13447:     if(!stat(plotcmd,&info)){
1.158     brouard  13448:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13449:     }else
                   13450:       strcpy(pplotcmd,plotcmd);
                   13451: #endif
                   13452:   }else
                   13453:     strcpy(pplotcmd,plotcmd);
                   13454:   
                   13455:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  13456:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.292     brouard  13457:   strcpy(pplotcmd,plotcmd);
1.227     brouard  13458:   
1.126     brouard  13459:   if((outcmd=system(plotcmd)) != 0){
1.292     brouard  13460:     printf("Error in gnuplot, command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  13461:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  13462:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.292     brouard  13463:     if((outcmd=system(plotcmd)) != 0){
1.153     brouard  13464:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.292     brouard  13465:       strcpy(plotcmd,pplotcmd);
                   13466:     }
1.126     brouard  13467:   }
1.158     brouard  13468:   printf(" Successful, please wait...");
1.126     brouard  13469:   while (z[0] != 'q') {
                   13470:     /* chdir(path); */
1.154     brouard  13471:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  13472:     scanf("%s",z);
                   13473: /*     if (z[0] == 'c') system("./imach"); */
                   13474:     if (z[0] == 'e') {
1.158     brouard  13475: #ifdef __APPLE__
1.152     brouard  13476:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  13477: #elif __linux
                   13478:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  13479: #else
1.152     brouard  13480:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  13481: #endif
                   13482:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   13483:       system(pplotcmd);
1.126     brouard  13484:     }
                   13485:     else if (z[0] == 'g') system(plotcmd);
                   13486:     else if (z[0] == 'q') exit(0);
                   13487:   }
1.227     brouard  13488: end:
1.126     brouard  13489:   while (z[0] != 'q') {
1.195     brouard  13490:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  13491:     scanf("%s",z);
                   13492:   }
1.283     brouard  13493:   printf("End\n");
1.282     brouard  13494:   exit(0);
1.126     brouard  13495: }

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