Annotation of imach/src/imach.c, revision 1.322

1.322   ! brouard     1: /* $Id: imach.c,v 1.321 2022/07/22 12:04:24 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.322   ! brouard     4:   Revision 1.321  2022/07/22 12:04:24  brouard
        !             5:   Summary: r28
        !             6: 
        !             7:   *  imach.c (Module): Output of Wald test in the htm file and not only in the log.
        !             8: 
1.321     brouard     9:   Revision 1.320  2022/06/02 05:10:11  brouard
                     10:   *** empty log message ***
                     11: 
1.320     brouard    12:   Revision 1.319  2022/06/02 04:45:11  brouard
                     13:   * imach.c (Module): Adding the Wald tests from the log to the main
                     14:   htm for better display of the maximum likelihood estimators.
                     15: 
1.319     brouard    16:   Revision 1.318  2022/05/24 08:10:59  brouard
                     17:   * imach.c (Module): Some attempts to find a bug of wrong estimates
                     18:   of confidencce intervals with product in the equation modelC
                     19: 
1.318     brouard    20:   Revision 1.317  2022/05/15 15:06:23  brouard
                     21:   * imach.c (Module):  Some minor improvements
                     22: 
1.317     brouard    23:   Revision 1.316  2022/05/11 15:11:31  brouard
                     24:   Summary: r27
                     25: 
1.316     brouard    26:   Revision 1.315  2022/05/11 15:06:32  brouard
                     27:   *** empty log message ***
                     28: 
1.315     brouard    29:   Revision 1.314  2022/04/13 17:43:09  brouard
                     30:   * imach.c (Module): Adding link to text data files
                     31: 
1.314     brouard    32:   Revision 1.313  2022/04/11 15:57:42  brouard
                     33:   * imach.c (Module): Error in rewriting the 'r' file with yearsfproj or yearsbproj fixed
                     34: 
1.313     brouard    35:   Revision 1.312  2022/04/05 21:24:39  brouard
                     36:   *** empty log message ***
                     37: 
1.312     brouard    38:   Revision 1.311  2022/04/05 21:03:51  brouard
                     39:   Summary: Fixed quantitative covariates
                     40: 
                     41:          Fixed covariates (dummy or quantitative)
                     42:        with missing values have never been allowed but are ERRORS and
                     43:        program quits. Standard deviations of fixed covariates were
                     44:        wrongly computed. Mean and standard deviations of time varying
                     45:        covariates are still not computed.
                     46: 
1.311     brouard    47:   Revision 1.310  2022/03/17 08:45:53  brouard
                     48:   Summary: 99r25
                     49: 
                     50:   Improving detection of errors: result lines should be compatible with
                     51:   the model.
                     52: 
1.310     brouard    53:   Revision 1.309  2021/05/20 12:39:14  brouard
                     54:   Summary: Version 0.99r24
                     55: 
1.309     brouard    56:   Revision 1.308  2021/03/31 13:11:57  brouard
                     57:   Summary: Version 0.99r23
                     58: 
                     59: 
                     60:   * imach.c (Module): Still bugs in the result loop. Thank to Holly Benett
                     61: 
1.308     brouard    62:   Revision 1.307  2021/03/08 18:11:32  brouard
                     63:   Summary: 0.99r22 fixed bug on result:
                     64: 
1.307     brouard    65:   Revision 1.306  2021/02/20 15:44:02  brouard
                     66:   Summary: Version 0.99r21
                     67: 
                     68:   * imach.c (Module): Fix bug on quitting after result lines!
                     69:   (Module): Version 0.99r21
                     70: 
1.306     brouard    71:   Revision 1.305  2021/02/20 15:28:30  brouard
                     72:   * imach.c (Module): Fix bug on quitting after result lines!
                     73: 
1.305     brouard    74:   Revision 1.304  2021/02/12 11:34:20  brouard
                     75:   * imach.c (Module): The use of a Windows BOM (huge) file is now an error
                     76: 
1.304     brouard    77:   Revision 1.303  2021/02/11 19:50:15  brouard
                     78:   *  (Module): imach.c Someone entered 'results:' instead of 'result:'. Now it is an error which is printed.
                     79: 
1.303     brouard    80:   Revision 1.302  2020/02/22 21:00:05  brouard
                     81:   *  (Module): imach.c Update mle=-3 (for computing Life expectancy
                     82:   and life table from the data without any state)
                     83: 
1.302     brouard    84:   Revision 1.301  2019/06/04 13:51:20  brouard
                     85:   Summary: Error in 'r'parameter file backcast yearsbproj instead of yearsfproj
                     86: 
1.301     brouard    87:   Revision 1.300  2019/05/22 19:09:45  brouard
                     88:   Summary: version 0.99r19 of May 2019
                     89: 
1.300     brouard    90:   Revision 1.299  2019/05/22 18:37:08  brouard
                     91:   Summary: Cleaned 0.99r19
                     92: 
1.299     brouard    93:   Revision 1.298  2019/05/22 18:19:56  brouard
                     94:   *** empty log message ***
                     95: 
1.298     brouard    96:   Revision 1.297  2019/05/22 17:56:10  brouard
                     97:   Summary: Fix bug by moving date2dmy and nhstepm which gaefin=-1
                     98: 
1.297     brouard    99:   Revision 1.296  2019/05/20 13:03:18  brouard
                    100:   Summary: Projection syntax simplified
                    101: 
                    102: 
                    103:   We can now start projections, forward or backward, from the mean date
                    104:   of inteviews up to or down to a number of years of projection:
                    105:   prevforecast=1 yearsfproj=15.3 mobil_average=0
                    106:   or
                    107:   prevforecast=1 starting-proj-date=1/1/2007 final-proj-date=12/31/2017 mobil_average=0
                    108:   or
                    109:   prevbackcast=1 yearsbproj=12.3 mobil_average=1
                    110:   or
                    111:   prevbackcast=1 starting-back-date=1/10/1999 final-back-date=1/1/1985 mobil_average=1
                    112: 
1.296     brouard   113:   Revision 1.295  2019/05/18 09:52:50  brouard
                    114:   Summary: doxygen tex bug
                    115: 
1.295     brouard   116:   Revision 1.294  2019/05/16 14:54:33  brouard
                    117:   Summary: There was some wrong lines added
                    118: 
1.294     brouard   119:   Revision 1.293  2019/05/09 15:17:34  brouard
                    120:   *** empty log message ***
                    121: 
1.293     brouard   122:   Revision 1.292  2019/05/09 14:17:20  brouard
                    123:   Summary: Some updates
                    124: 
1.292     brouard   125:   Revision 1.291  2019/05/09 13:44:18  brouard
                    126:   Summary: Before ncovmax
                    127: 
1.291     brouard   128:   Revision 1.290  2019/05/09 13:39:37  brouard
                    129:   Summary: 0.99r18 unlimited number of individuals
                    130: 
                    131:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
                    132: 
1.290     brouard   133:   Revision 1.289  2018/12/13 09:16:26  brouard
                    134:   Summary: Bug for young ages (<-30) will be in r17
                    135: 
1.289     brouard   136:   Revision 1.288  2018/05/02 20:58:27  brouard
                    137:   Summary: Some bugs fixed
                    138: 
1.288     brouard   139:   Revision 1.287  2018/05/01 17:57:25  brouard
                    140:   Summary: Bug fixed by providing frequencies only for non missing covariates
                    141: 
1.287     brouard   142:   Revision 1.286  2018/04/27 14:27:04  brouard
                    143:   Summary: some minor bugs
                    144: 
1.286     brouard   145:   Revision 1.285  2018/04/21 21:02:16  brouard
                    146:   Summary: Some bugs fixed, valgrind tested
                    147: 
1.285     brouard   148:   Revision 1.284  2018/04/20 05:22:13  brouard
                    149:   Summary: Computing mean and stdeviation of fixed quantitative variables
                    150: 
1.284     brouard   151:   Revision 1.283  2018/04/19 14:49:16  brouard
                    152:   Summary: Some minor bugs fixed
                    153: 
1.283     brouard   154:   Revision 1.282  2018/02/27 22:50:02  brouard
                    155:   *** empty log message ***
                    156: 
1.282     brouard   157:   Revision 1.281  2018/02/27 19:25:23  brouard
                    158:   Summary: Adding second argument for quitting
                    159: 
1.281     brouard   160:   Revision 1.280  2018/02/21 07:58:13  brouard
                    161:   Summary: 0.99r15
                    162: 
                    163:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                    164: 
1.280     brouard   165:   Revision 1.279  2017/07/20 13:35:01  brouard
                    166:   Summary: temporary working
                    167: 
1.279     brouard   168:   Revision 1.278  2017/07/19 14:09:02  brouard
                    169:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                    170: 
1.278     brouard   171:   Revision 1.277  2017/07/17 08:53:49  brouard
                    172:   Summary: BOM files can be read now
                    173: 
1.277     brouard   174:   Revision 1.276  2017/06/30 15:48:31  brouard
                    175:   Summary: Graphs improvements
                    176: 
1.276     brouard   177:   Revision 1.275  2017/06/30 13:39:33  brouard
                    178:   Summary: Saito's color
                    179: 
1.275     brouard   180:   Revision 1.274  2017/06/29 09:47:08  brouard
                    181:   Summary: Version 0.99r14
                    182: 
1.274     brouard   183:   Revision 1.273  2017/06/27 11:06:02  brouard
                    184:   Summary: More documentation on projections
                    185: 
1.273     brouard   186:   Revision 1.272  2017/06/27 10:22:40  brouard
                    187:   Summary: Color of backprojection changed from 6 to 5(yellow)
                    188: 
1.272     brouard   189:   Revision 1.271  2017/06/27 10:17:50  brouard
                    190:   Summary: Some bug with rint
                    191: 
1.271     brouard   192:   Revision 1.270  2017/05/24 05:45:29  brouard
                    193:   *** empty log message ***
                    194: 
1.270     brouard   195:   Revision 1.269  2017/05/23 08:39:25  brouard
                    196:   Summary: Code into subroutine, cleanings
                    197: 
1.269     brouard   198:   Revision 1.268  2017/05/18 20:09:32  brouard
                    199:   Summary: backprojection and confidence intervals of backprevalence
                    200: 
1.268     brouard   201:   Revision 1.267  2017/05/13 10:25:05  brouard
                    202:   Summary: temporary save for backprojection
                    203: 
1.267     brouard   204:   Revision 1.266  2017/05/13 07:26:12  brouard
                    205:   Summary: Version 0.99r13 (improvements and bugs fixed)
                    206: 
1.266     brouard   207:   Revision 1.265  2017/04/26 16:22:11  brouard
                    208:   Summary: imach 0.99r13 Some bugs fixed
                    209: 
1.265     brouard   210:   Revision 1.264  2017/04/26 06:01:29  brouard
                    211:   Summary: Labels in graphs
                    212: 
1.264     brouard   213:   Revision 1.263  2017/04/24 15:23:15  brouard
                    214:   Summary: to save
                    215: 
1.263     brouard   216:   Revision 1.262  2017/04/18 16:48:12  brouard
                    217:   *** empty log message ***
                    218: 
1.262     brouard   219:   Revision 1.261  2017/04/05 10:14:09  brouard
                    220:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                    221: 
1.261     brouard   222:   Revision 1.260  2017/04/04 17:46:59  brouard
                    223:   Summary: Gnuplot indexations fixed (humm)
                    224: 
1.260     brouard   225:   Revision 1.259  2017/04/04 13:01:16  brouard
                    226:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    227: 
1.259     brouard   228:   Revision 1.258  2017/04/03 10:17:47  brouard
                    229:   Summary: Version 0.99r12
                    230: 
                    231:   Some cleanings, conformed with updated documentation.
                    232: 
1.258     brouard   233:   Revision 1.257  2017/03/29 16:53:30  brouard
                    234:   Summary: Temp
                    235: 
1.257     brouard   236:   Revision 1.256  2017/03/27 05:50:23  brouard
                    237:   Summary: Temporary
                    238: 
1.256     brouard   239:   Revision 1.255  2017/03/08 16:02:28  brouard
                    240:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    241: 
1.255     brouard   242:   Revision 1.254  2017/03/08 07:13:00  brouard
                    243:   Summary: Fixing data parameter line
                    244: 
1.254     brouard   245:   Revision 1.253  2016/12/15 11:59:41  brouard
                    246:   Summary: 0.99 in progress
                    247: 
1.253     brouard   248:   Revision 1.252  2016/09/15 21:15:37  brouard
                    249:   *** empty log message ***
                    250: 
1.252     brouard   251:   Revision 1.251  2016/09/15 15:01:13  brouard
                    252:   Summary: not working
                    253: 
1.251     brouard   254:   Revision 1.250  2016/09/08 16:07:27  brouard
                    255:   Summary: continue
                    256: 
1.250     brouard   257:   Revision 1.249  2016/09/07 17:14:18  brouard
                    258:   Summary: Starting values from frequencies
                    259: 
1.249     brouard   260:   Revision 1.248  2016/09/07 14:10:18  brouard
                    261:   *** empty log message ***
                    262: 
1.248     brouard   263:   Revision 1.247  2016/09/02 11:11:21  brouard
                    264:   *** empty log message ***
                    265: 
1.247     brouard   266:   Revision 1.246  2016/09/02 08:49:22  brouard
                    267:   *** empty log message ***
                    268: 
1.246     brouard   269:   Revision 1.245  2016/09/02 07:25:01  brouard
                    270:   *** empty log message ***
                    271: 
1.245     brouard   272:   Revision 1.244  2016/09/02 07:17:34  brouard
                    273:   *** empty log message ***
                    274: 
1.244     brouard   275:   Revision 1.243  2016/09/02 06:45:35  brouard
                    276:   *** empty log message ***
                    277: 
1.243     brouard   278:   Revision 1.242  2016/08/30 15:01:20  brouard
                    279:   Summary: Fixing a lots
                    280: 
1.242     brouard   281:   Revision 1.241  2016/08/29 17:17:25  brouard
                    282:   Summary: gnuplot problem in Back projection to fix
                    283: 
1.241     brouard   284:   Revision 1.240  2016/08/29 07:53:18  brouard
                    285:   Summary: Better
                    286: 
1.240     brouard   287:   Revision 1.239  2016/08/26 15:51:03  brouard
                    288:   Summary: Improvement in Powell output in order to copy and paste
                    289: 
                    290:   Author:
                    291: 
1.239     brouard   292:   Revision 1.238  2016/08/26 14:23:35  brouard
                    293:   Summary: Starting tests of 0.99
                    294: 
1.238     brouard   295:   Revision 1.237  2016/08/26 09:20:19  brouard
                    296:   Summary: to valgrind
                    297: 
1.237     brouard   298:   Revision 1.236  2016/08/25 10:50:18  brouard
                    299:   *** empty log message ***
                    300: 
1.236     brouard   301:   Revision 1.235  2016/08/25 06:59:23  brouard
                    302:   *** empty log message ***
                    303: 
1.235     brouard   304:   Revision 1.234  2016/08/23 16:51:20  brouard
                    305:   *** empty log message ***
                    306: 
1.234     brouard   307:   Revision 1.233  2016/08/23 07:40:50  brouard
                    308:   Summary: not working
                    309: 
1.233     brouard   310:   Revision 1.232  2016/08/22 14:20:21  brouard
                    311:   Summary: not working
                    312: 
1.232     brouard   313:   Revision 1.231  2016/08/22 07:17:15  brouard
                    314:   Summary: not working
                    315: 
1.231     brouard   316:   Revision 1.230  2016/08/22 06:55:53  brouard
                    317:   Summary: Not working
                    318: 
1.230     brouard   319:   Revision 1.229  2016/07/23 09:45:53  brouard
                    320:   Summary: Completing for func too
                    321: 
1.229     brouard   322:   Revision 1.228  2016/07/22 17:45:30  brouard
                    323:   Summary: Fixing some arrays, still debugging
                    324: 
1.227     brouard   325:   Revision 1.226  2016/07/12 18:42:34  brouard
                    326:   Summary: temp
                    327: 
1.226     brouard   328:   Revision 1.225  2016/07/12 08:40:03  brouard
                    329:   Summary: saving but not running
                    330: 
1.225     brouard   331:   Revision 1.224  2016/07/01 13:16:01  brouard
                    332:   Summary: Fixes
                    333: 
1.224     brouard   334:   Revision 1.223  2016/02/19 09:23:35  brouard
                    335:   Summary: temporary
                    336: 
1.223     brouard   337:   Revision 1.222  2016/02/17 08:14:50  brouard
                    338:   Summary: Probably last 0.98 stable version 0.98r6
                    339: 
1.222     brouard   340:   Revision 1.221  2016/02/15 23:35:36  brouard
                    341:   Summary: minor bug
                    342: 
1.220     brouard   343:   Revision 1.219  2016/02/15 00:48:12  brouard
                    344:   *** empty log message ***
                    345: 
1.219     brouard   346:   Revision 1.218  2016/02/12 11:29:23  brouard
                    347:   Summary: 0.99 Back projections
                    348: 
1.218     brouard   349:   Revision 1.217  2015/12/23 17:18:31  brouard
                    350:   Summary: Experimental backcast
                    351: 
1.217     brouard   352:   Revision 1.216  2015/12/18 17:32:11  brouard
                    353:   Summary: 0.98r4 Warning and status=-2
                    354: 
                    355:   Version 0.98r4 is now:
                    356:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    357:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    358:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    359: 
1.216     brouard   360:   Revision 1.215  2015/12/16 08:52:24  brouard
                    361:   Summary: 0.98r4 working
                    362: 
1.215     brouard   363:   Revision 1.214  2015/12/16 06:57:54  brouard
                    364:   Summary: temporary not working
                    365: 
1.214     brouard   366:   Revision 1.213  2015/12/11 18:22:17  brouard
                    367:   Summary: 0.98r4
                    368: 
1.213     brouard   369:   Revision 1.212  2015/11/21 12:47:24  brouard
                    370:   Summary: minor typo
                    371: 
1.212     brouard   372:   Revision 1.211  2015/11/21 12:41:11  brouard
                    373:   Summary: 0.98r3 with some graph of projected cross-sectional
                    374: 
                    375:   Author: Nicolas Brouard
                    376: 
1.211     brouard   377:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   378:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   379:   Summary: Adding ftolpl parameter
                    380:   Author: N Brouard
                    381: 
                    382:   We had difficulties to get smoothed confidence intervals. It was due
                    383:   to the period prevalence which wasn't computed accurately. The inner
                    384:   parameter ftolpl is now an outer parameter of the .imach parameter
                    385:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    386:   computation are long.
                    387: 
1.209     brouard   388:   Revision 1.208  2015/11/17 14:31:57  brouard
                    389:   Summary: temporary
                    390: 
1.208     brouard   391:   Revision 1.207  2015/10/27 17:36:57  brouard
                    392:   *** empty log message ***
                    393: 
1.207     brouard   394:   Revision 1.206  2015/10/24 07:14:11  brouard
                    395:   *** empty log message ***
                    396: 
1.206     brouard   397:   Revision 1.205  2015/10/23 15:50:53  brouard
                    398:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    399: 
1.205     brouard   400:   Revision 1.204  2015/10/01 16:20:26  brouard
                    401:   Summary: Some new graphs of contribution to likelihood
                    402: 
1.204     brouard   403:   Revision 1.203  2015/09/30 17:45:14  brouard
                    404:   Summary: looking at better estimation of the hessian
                    405: 
                    406:   Also a better criteria for convergence to the period prevalence And
                    407:   therefore adding the number of years needed to converge. (The
                    408:   prevalence in any alive state shold sum to one
                    409: 
1.203     brouard   410:   Revision 1.202  2015/09/22 19:45:16  brouard
                    411:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    412: 
1.202     brouard   413:   Revision 1.201  2015/09/15 17:34:58  brouard
                    414:   Summary: 0.98r0
                    415: 
                    416:   - Some new graphs like suvival functions
                    417:   - Some bugs fixed like model=1+age+V2.
                    418: 
1.201     brouard   419:   Revision 1.200  2015/09/09 16:53:55  brouard
                    420:   Summary: Big bug thanks to Flavia
                    421: 
                    422:   Even model=1+age+V2. did not work anymore
                    423: 
1.200     brouard   424:   Revision 1.199  2015/09/07 14:09:23  brouard
                    425:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    426: 
1.199     brouard   427:   Revision 1.198  2015/09/03 07:14:39  brouard
                    428:   Summary: 0.98q5 Flavia
                    429: 
1.198     brouard   430:   Revision 1.197  2015/09/01 18:24:39  brouard
                    431:   *** empty log message ***
                    432: 
1.197     brouard   433:   Revision 1.196  2015/08/18 23:17:52  brouard
                    434:   Summary: 0.98q5
                    435: 
1.196     brouard   436:   Revision 1.195  2015/08/18 16:28:39  brouard
                    437:   Summary: Adding a hack for testing purpose
                    438: 
                    439:   After reading the title, ftol and model lines, if the comment line has
                    440:   a q, starting with #q, the answer at the end of the run is quit. It
                    441:   permits to run test files in batch with ctest. The former workaround was
                    442:   $ echo q | imach foo.imach
                    443: 
1.195     brouard   444:   Revision 1.194  2015/08/18 13:32:00  brouard
                    445:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    446: 
1.194     brouard   447:   Revision 1.193  2015/08/04 07:17:42  brouard
                    448:   Summary: 0.98q4
                    449: 
1.193     brouard   450:   Revision 1.192  2015/07/16 16:49:02  brouard
                    451:   Summary: Fixing some outputs
                    452: 
1.192     brouard   453:   Revision 1.191  2015/07/14 10:00:33  brouard
                    454:   Summary: Some fixes
                    455: 
1.191     brouard   456:   Revision 1.190  2015/05/05 08:51:13  brouard
                    457:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    458: 
                    459:   Fix 1+age+.
                    460: 
1.190     brouard   461:   Revision 1.189  2015/04/30 14:45:16  brouard
                    462:   Summary: 0.98q2
                    463: 
1.189     brouard   464:   Revision 1.188  2015/04/30 08:27:53  brouard
                    465:   *** empty log message ***
                    466: 
1.188     brouard   467:   Revision 1.187  2015/04/29 09:11:15  brouard
                    468:   *** empty log message ***
                    469: 
1.187     brouard   470:   Revision 1.186  2015/04/23 12:01:52  brouard
                    471:   Summary: V1*age is working now, version 0.98q1
                    472: 
                    473:   Some codes had been disabled in order to simplify and Vn*age was
                    474:   working in the optimization phase, ie, giving correct MLE parameters,
                    475:   but, as usual, outputs were not correct and program core dumped.
                    476: 
1.186     brouard   477:   Revision 1.185  2015/03/11 13:26:42  brouard
                    478:   Summary: Inclusion of compile and links command line for Intel Compiler
                    479: 
1.185     brouard   480:   Revision 1.184  2015/03/11 11:52:39  brouard
                    481:   Summary: Back from Windows 8. Intel Compiler
                    482: 
1.184     brouard   483:   Revision 1.183  2015/03/10 20:34:32  brouard
                    484:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    485: 
                    486:   We use directest instead of original Powell test; probably no
                    487:   incidence on the results, but better justifications;
                    488:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    489:   wrong results.
                    490: 
1.183     brouard   491:   Revision 1.182  2015/02/12 08:19:57  brouard
                    492:   Summary: Trying to keep directest which seems simpler and more general
                    493:   Author: Nicolas Brouard
                    494: 
1.182     brouard   495:   Revision 1.181  2015/02/11 23:22:24  brouard
                    496:   Summary: Comments on Powell added
                    497: 
                    498:   Author:
                    499: 
1.181     brouard   500:   Revision 1.180  2015/02/11 17:33:45  brouard
                    501:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    502: 
1.180     brouard   503:   Revision 1.179  2015/01/04 09:57:06  brouard
                    504:   Summary: back to OS/X
                    505: 
1.179     brouard   506:   Revision 1.178  2015/01/04 09:35:48  brouard
                    507:   *** empty log message ***
                    508: 
1.178     brouard   509:   Revision 1.177  2015/01/03 18:40:56  brouard
                    510:   Summary: Still testing ilc32 on OSX
                    511: 
1.177     brouard   512:   Revision 1.176  2015/01/03 16:45:04  brouard
                    513:   *** empty log message ***
                    514: 
1.176     brouard   515:   Revision 1.175  2015/01/03 16:33:42  brouard
                    516:   *** empty log message ***
                    517: 
1.175     brouard   518:   Revision 1.174  2015/01/03 16:15:49  brouard
                    519:   Summary: Still in cross-compilation
                    520: 
1.174     brouard   521:   Revision 1.173  2015/01/03 12:06:26  brouard
                    522:   Summary: trying to detect cross-compilation
                    523: 
1.173     brouard   524:   Revision 1.172  2014/12/27 12:07:47  brouard
                    525:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    526: 
1.172     brouard   527:   Revision 1.171  2014/12/23 13:26:59  brouard
                    528:   Summary: Back from Visual C
                    529: 
                    530:   Still problem with utsname.h on Windows
                    531: 
1.171     brouard   532:   Revision 1.170  2014/12/23 11:17:12  brouard
                    533:   Summary: Cleaning some \%% back to %%
                    534: 
                    535:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    536: 
1.170     brouard   537:   Revision 1.169  2014/12/22 23:08:31  brouard
                    538:   Summary: 0.98p
                    539: 
                    540:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    541: 
1.169     brouard   542:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   543:   Summary: update
1.169     brouard   544: 
1.168     brouard   545:   Revision 1.167  2014/12/22 13:50:56  brouard
                    546:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    547: 
                    548:   Testing on Linux 64
                    549: 
1.167     brouard   550:   Revision 1.166  2014/12/22 11:40:47  brouard
                    551:   *** empty log message ***
                    552: 
1.166     brouard   553:   Revision 1.165  2014/12/16 11:20:36  brouard
                    554:   Summary: After compiling on Visual C
                    555: 
                    556:   * imach.c (Module): Merging 1.61 to 1.162
                    557: 
1.165     brouard   558:   Revision 1.164  2014/12/16 10:52:11  brouard
                    559:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    560: 
                    561:   * imach.c (Module): Merging 1.61 to 1.162
                    562: 
1.164     brouard   563:   Revision 1.163  2014/12/16 10:30:11  brouard
                    564:   * imach.c (Module): Merging 1.61 to 1.162
                    565: 
1.163     brouard   566:   Revision 1.162  2014/09/25 11:43:39  brouard
                    567:   Summary: temporary backup 0.99!
                    568: 
1.162     brouard   569:   Revision 1.1  2014/09/16 11:06:58  brouard
                    570:   Summary: With some code (wrong) for nlopt
                    571: 
                    572:   Author:
                    573: 
                    574:   Revision 1.161  2014/09/15 20:41:41  brouard
                    575:   Summary: Problem with macro SQR on Intel compiler
                    576: 
1.161     brouard   577:   Revision 1.160  2014/09/02 09:24:05  brouard
                    578:   *** empty log message ***
                    579: 
1.160     brouard   580:   Revision 1.159  2014/09/01 10:34:10  brouard
                    581:   Summary: WIN32
                    582:   Author: Brouard
                    583: 
1.159     brouard   584:   Revision 1.158  2014/08/27 17:11:51  brouard
                    585:   *** empty log message ***
                    586: 
1.158     brouard   587:   Revision 1.157  2014/08/27 16:26:55  brouard
                    588:   Summary: Preparing windows Visual studio version
                    589:   Author: Brouard
                    590: 
                    591:   In order to compile on Visual studio, time.h is now correct and time_t
                    592:   and tm struct should be used. difftime should be used but sometimes I
                    593:   just make the differences in raw time format (time(&now).
                    594:   Trying to suppress #ifdef LINUX
                    595:   Add xdg-open for __linux in order to open default browser.
                    596: 
1.157     brouard   597:   Revision 1.156  2014/08/25 20:10:10  brouard
                    598:   *** empty log message ***
                    599: 
1.156     brouard   600:   Revision 1.155  2014/08/25 18:32:34  brouard
                    601:   Summary: New compile, minor changes
                    602:   Author: Brouard
                    603: 
1.155     brouard   604:   Revision 1.154  2014/06/20 17:32:08  brouard
                    605:   Summary: Outputs now all graphs of convergence to period prevalence
                    606: 
1.154     brouard   607:   Revision 1.153  2014/06/20 16:45:46  brouard
                    608:   Summary: If 3 live state, convergence to period prevalence on same graph
                    609:   Author: Brouard
                    610: 
1.153     brouard   611:   Revision 1.152  2014/06/18 17:54:09  brouard
                    612:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    613: 
1.152     brouard   614:   Revision 1.151  2014/06/18 16:43:30  brouard
                    615:   *** empty log message ***
                    616: 
1.151     brouard   617:   Revision 1.150  2014/06/18 16:42:35  brouard
                    618:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    619:   Author: brouard
                    620: 
1.150     brouard   621:   Revision 1.149  2014/06/18 15:51:14  brouard
                    622:   Summary: Some fixes in parameter files errors
                    623:   Author: Nicolas Brouard
                    624: 
1.149     brouard   625:   Revision 1.148  2014/06/17 17:38:48  brouard
                    626:   Summary: Nothing new
                    627:   Author: Brouard
                    628: 
                    629:   Just a new packaging for OS/X version 0.98nS
                    630: 
1.148     brouard   631:   Revision 1.147  2014/06/16 10:33:11  brouard
                    632:   *** empty log message ***
                    633: 
1.147     brouard   634:   Revision 1.146  2014/06/16 10:20:28  brouard
                    635:   Summary: Merge
                    636:   Author: Brouard
                    637: 
                    638:   Merge, before building revised version.
                    639: 
1.146     brouard   640:   Revision 1.145  2014/06/10 21:23:15  brouard
                    641:   Summary: Debugging with valgrind
                    642:   Author: Nicolas Brouard
                    643: 
                    644:   Lot of changes in order to output the results with some covariates
                    645:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    646:   improve the code.
                    647:   No more memory valgrind error but a lot has to be done in order to
                    648:   continue the work of splitting the code into subroutines.
                    649:   Also, decodemodel has been improved. Tricode is still not
                    650:   optimal. nbcode should be improved. Documentation has been added in
                    651:   the source code.
                    652: 
1.144     brouard   653:   Revision 1.143  2014/01/26 09:45:38  brouard
                    654:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    655: 
                    656:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    657:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    658: 
1.143     brouard   659:   Revision 1.142  2014/01/26 03:57:36  brouard
                    660:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    661: 
                    662:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    663: 
1.142     brouard   664:   Revision 1.141  2014/01/26 02:42:01  brouard
                    665:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    666: 
1.141     brouard   667:   Revision 1.140  2011/09/02 10:37:54  brouard
                    668:   Summary: times.h is ok with mingw32 now.
                    669: 
1.140     brouard   670:   Revision 1.139  2010/06/14 07:50:17  brouard
                    671:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    672:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    673: 
1.139     brouard   674:   Revision 1.138  2010/04/30 18:19:40  brouard
                    675:   *** empty log message ***
                    676: 
1.138     brouard   677:   Revision 1.137  2010/04/29 18:11:38  brouard
                    678:   (Module): Checking covariates for more complex models
                    679:   than V1+V2. A lot of change to be done. Unstable.
                    680: 
1.137     brouard   681:   Revision 1.136  2010/04/26 20:30:53  brouard
                    682:   (Module): merging some libgsl code. Fixing computation
                    683:   of likelione (using inter/intrapolation if mle = 0) in order to
                    684:   get same likelihood as if mle=1.
                    685:   Some cleaning of code and comments added.
                    686: 
1.136     brouard   687:   Revision 1.135  2009/10/29 15:33:14  brouard
                    688:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    689: 
1.135     brouard   690:   Revision 1.134  2009/10/29 13:18:53  brouard
                    691:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    692: 
1.134     brouard   693:   Revision 1.133  2009/07/06 10:21:25  brouard
                    694:   just nforces
                    695: 
1.133     brouard   696:   Revision 1.132  2009/07/06 08:22:05  brouard
                    697:   Many tings
                    698: 
1.132     brouard   699:   Revision 1.131  2009/06/20 16:22:47  brouard
                    700:   Some dimensions resccaled
                    701: 
1.131     brouard   702:   Revision 1.130  2009/05/26 06:44:34  brouard
                    703:   (Module): Max Covariate is now set to 20 instead of 8. A
                    704:   lot of cleaning with variables initialized to 0. Trying to make
                    705:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    706: 
1.130     brouard   707:   Revision 1.129  2007/08/31 13:49:27  lievre
                    708:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    709: 
1.129     lievre    710:   Revision 1.128  2006/06/30 13:02:05  brouard
                    711:   (Module): Clarifications on computing e.j
                    712: 
1.128     brouard   713:   Revision 1.127  2006/04/28 18:11:50  brouard
                    714:   (Module): Yes the sum of survivors was wrong since
                    715:   imach-114 because nhstepm was no more computed in the age
                    716:   loop. Now we define nhstepma in the age loop.
                    717:   (Module): In order to speed up (in case of numerous covariates) we
                    718:   compute health expectancies (without variances) in a first step
                    719:   and then all the health expectancies with variances or standard
                    720:   deviation (needs data from the Hessian matrices) which slows the
                    721:   computation.
                    722:   In the future we should be able to stop the program is only health
                    723:   expectancies and graph are needed without standard deviations.
                    724: 
1.127     brouard   725:   Revision 1.126  2006/04/28 17:23:28  brouard
                    726:   (Module): Yes the sum of survivors was wrong since
                    727:   imach-114 because nhstepm was no more computed in the age
                    728:   loop. Now we define nhstepma in the age loop.
                    729:   Version 0.98h
                    730: 
1.126     brouard   731:   Revision 1.125  2006/04/04 15:20:31  lievre
                    732:   Errors in calculation of health expectancies. Age was not initialized.
                    733:   Forecasting file added.
                    734: 
                    735:   Revision 1.124  2006/03/22 17:13:53  lievre
                    736:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    737:   The log-likelihood is printed in the log file
                    738: 
                    739:   Revision 1.123  2006/03/20 10:52:43  brouard
                    740:   * imach.c (Module): <title> changed, corresponds to .htm file
                    741:   name. <head> headers where missing.
                    742: 
                    743:   * imach.c (Module): Weights can have a decimal point as for
                    744:   English (a comma might work with a correct LC_NUMERIC environment,
                    745:   otherwise the weight is truncated).
                    746:   Modification of warning when the covariates values are not 0 or
                    747:   1.
                    748:   Version 0.98g
                    749: 
                    750:   Revision 1.122  2006/03/20 09:45:41  brouard
                    751:   (Module): Weights can have a decimal point as for
                    752:   English (a comma might work with a correct LC_NUMERIC environment,
                    753:   otherwise the weight is truncated).
                    754:   Modification of warning when the covariates values are not 0 or
                    755:   1.
                    756:   Version 0.98g
                    757: 
                    758:   Revision 1.121  2006/03/16 17:45:01  lievre
                    759:   * imach.c (Module): Comments concerning covariates added
                    760: 
                    761:   * imach.c (Module): refinements in the computation of lli if
                    762:   status=-2 in order to have more reliable computation if stepm is
                    763:   not 1 month. Version 0.98f
                    764: 
                    765:   Revision 1.120  2006/03/16 15:10:38  lievre
                    766:   (Module): refinements in the computation of lli if
                    767:   status=-2 in order to have more reliable computation if stepm is
                    768:   not 1 month. Version 0.98f
                    769: 
                    770:   Revision 1.119  2006/03/15 17:42:26  brouard
                    771:   (Module): Bug if status = -2, the loglikelihood was
                    772:   computed as likelihood omitting the logarithm. Version O.98e
                    773: 
                    774:   Revision 1.118  2006/03/14 18:20:07  brouard
                    775:   (Module): varevsij Comments added explaining the second
                    776:   table of variances if popbased=1 .
                    777:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    778:   (Module): Function pstamp added
                    779:   (Module): Version 0.98d
                    780: 
                    781:   Revision 1.117  2006/03/14 17:16:22  brouard
                    782:   (Module): varevsij Comments added explaining the second
                    783:   table of variances if popbased=1 .
                    784:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    785:   (Module): Function pstamp added
                    786:   (Module): Version 0.98d
                    787: 
                    788:   Revision 1.116  2006/03/06 10:29:27  brouard
                    789:   (Module): Variance-covariance wrong links and
                    790:   varian-covariance of ej. is needed (Saito).
                    791: 
                    792:   Revision 1.115  2006/02/27 12:17:45  brouard
                    793:   (Module): One freematrix added in mlikeli! 0.98c
                    794: 
                    795:   Revision 1.114  2006/02/26 12:57:58  brouard
                    796:   (Module): Some improvements in processing parameter
                    797:   filename with strsep.
                    798: 
                    799:   Revision 1.113  2006/02/24 14:20:24  brouard
                    800:   (Module): Memory leaks checks with valgrind and:
                    801:   datafile was not closed, some imatrix were not freed and on matrix
                    802:   allocation too.
                    803: 
                    804:   Revision 1.112  2006/01/30 09:55:26  brouard
                    805:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    806: 
                    807:   Revision 1.111  2006/01/25 20:38:18  brouard
                    808:   (Module): Lots of cleaning and bugs added (Gompertz)
                    809:   (Module): Comments can be added in data file. Missing date values
                    810:   can be a simple dot '.'.
                    811: 
                    812:   Revision 1.110  2006/01/25 00:51:50  brouard
                    813:   (Module): Lots of cleaning and bugs added (Gompertz)
                    814: 
                    815:   Revision 1.109  2006/01/24 19:37:15  brouard
                    816:   (Module): Comments (lines starting with a #) are allowed in data.
                    817: 
                    818:   Revision 1.108  2006/01/19 18:05:42  lievre
                    819:   Gnuplot problem appeared...
                    820:   To be fixed
                    821: 
                    822:   Revision 1.107  2006/01/19 16:20:37  brouard
                    823:   Test existence of gnuplot in imach path
                    824: 
                    825:   Revision 1.106  2006/01/19 13:24:36  brouard
                    826:   Some cleaning and links added in html output
                    827: 
                    828:   Revision 1.105  2006/01/05 20:23:19  lievre
                    829:   *** empty log message ***
                    830: 
                    831:   Revision 1.104  2005/09/30 16:11:43  lievre
                    832:   (Module): sump fixed, loop imx fixed, and simplifications.
                    833:   (Module): If the status is missing at the last wave but we know
                    834:   that the person is alive, then we can code his/her status as -2
                    835:   (instead of missing=-1 in earlier versions) and his/her
                    836:   contributions to the likelihood is 1 - Prob of dying from last
                    837:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    838:   the healthy state at last known wave). Version is 0.98
                    839: 
                    840:   Revision 1.103  2005/09/30 15:54:49  lievre
                    841:   (Module): sump fixed, loop imx fixed, and simplifications.
                    842: 
                    843:   Revision 1.102  2004/09/15 17:31:30  brouard
                    844:   Add the possibility to read data file including tab characters.
                    845: 
                    846:   Revision 1.101  2004/09/15 10:38:38  brouard
                    847:   Fix on curr_time
                    848: 
                    849:   Revision 1.100  2004/07/12 18:29:06  brouard
                    850:   Add version for Mac OS X. Just define UNIX in Makefile
                    851: 
                    852:   Revision 1.99  2004/06/05 08:57:40  brouard
                    853:   *** empty log message ***
                    854: 
                    855:   Revision 1.98  2004/05/16 15:05:56  brouard
                    856:   New version 0.97 . First attempt to estimate force of mortality
                    857:   directly from the data i.e. without the need of knowing the health
                    858:   state at each age, but using a Gompertz model: log u =a + b*age .
                    859:   This is the basic analysis of mortality and should be done before any
                    860:   other analysis, in order to test if the mortality estimated from the
                    861:   cross-longitudinal survey is different from the mortality estimated
                    862:   from other sources like vital statistic data.
                    863: 
                    864:   The same imach parameter file can be used but the option for mle should be -3.
                    865: 
1.133     brouard   866:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   867:   former routines in order to include the new code within the former code.
                    868: 
                    869:   The output is very simple: only an estimate of the intercept and of
                    870:   the slope with 95% confident intervals.
                    871: 
                    872:   Current limitations:
                    873:   A) Even if you enter covariates, i.e. with the
                    874:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    875:   B) There is no computation of Life Expectancy nor Life Table.
                    876: 
                    877:   Revision 1.97  2004/02/20 13:25:42  lievre
                    878:   Version 0.96d. Population forecasting command line is (temporarily)
                    879:   suppressed.
                    880: 
                    881:   Revision 1.96  2003/07/15 15:38:55  brouard
                    882:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    883:   rewritten within the same printf. Workaround: many printfs.
                    884: 
                    885:   Revision 1.95  2003/07/08 07:54:34  brouard
                    886:   * imach.c (Repository):
                    887:   (Repository): Using imachwizard code to output a more meaningful covariance
                    888:   matrix (cov(a12,c31) instead of numbers.
                    889: 
                    890:   Revision 1.94  2003/06/27 13:00:02  brouard
                    891:   Just cleaning
                    892: 
                    893:   Revision 1.93  2003/06/25 16:33:55  brouard
                    894:   (Module): On windows (cygwin) function asctime_r doesn't
                    895:   exist so I changed back to asctime which exists.
                    896:   (Module): Version 0.96b
                    897: 
                    898:   Revision 1.92  2003/06/25 16:30:45  brouard
                    899:   (Module): On windows (cygwin) function asctime_r doesn't
                    900:   exist so I changed back to asctime which exists.
                    901: 
                    902:   Revision 1.91  2003/06/25 15:30:29  brouard
                    903:   * imach.c (Repository): Duplicated warning errors corrected.
                    904:   (Repository): Elapsed time after each iteration is now output. It
                    905:   helps to forecast when convergence will be reached. Elapsed time
                    906:   is stamped in powell.  We created a new html file for the graphs
                    907:   concerning matrix of covariance. It has extension -cov.htm.
                    908: 
                    909:   Revision 1.90  2003/06/24 12:34:15  brouard
                    910:   (Module): Some bugs corrected for windows. Also, when
                    911:   mle=-1 a template is output in file "or"mypar.txt with the design
                    912:   of the covariance matrix to be input.
                    913: 
                    914:   Revision 1.89  2003/06/24 12:30:52  brouard
                    915:   (Module): Some bugs corrected for windows. Also, when
                    916:   mle=-1 a template is output in file "or"mypar.txt with the design
                    917:   of the covariance matrix to be input.
                    918: 
                    919:   Revision 1.88  2003/06/23 17:54:56  brouard
                    920:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    921: 
                    922:   Revision 1.87  2003/06/18 12:26:01  brouard
                    923:   Version 0.96
                    924: 
                    925:   Revision 1.86  2003/06/17 20:04:08  brouard
                    926:   (Module): Change position of html and gnuplot routines and added
                    927:   routine fileappend.
                    928: 
                    929:   Revision 1.85  2003/06/17 13:12:43  brouard
                    930:   * imach.c (Repository): Check when date of death was earlier that
                    931:   current date of interview. It may happen when the death was just
                    932:   prior to the death. In this case, dh was negative and likelihood
                    933:   was wrong (infinity). We still send an "Error" but patch by
                    934:   assuming that the date of death was just one stepm after the
                    935:   interview.
                    936:   (Repository): Because some people have very long ID (first column)
                    937:   we changed int to long in num[] and we added a new lvector for
                    938:   memory allocation. But we also truncated to 8 characters (left
                    939:   truncation)
                    940:   (Repository): No more line truncation errors.
                    941: 
                    942:   Revision 1.84  2003/06/13 21:44:43  brouard
                    943:   * imach.c (Repository): Replace "freqsummary" at a correct
                    944:   place. It differs from routine "prevalence" which may be called
                    945:   many times. Probs is memory consuming and must be used with
                    946:   parcimony.
                    947:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    948: 
                    949:   Revision 1.83  2003/06/10 13:39:11  lievre
                    950:   *** empty log message ***
                    951: 
                    952:   Revision 1.82  2003/06/05 15:57:20  brouard
                    953:   Add log in  imach.c and  fullversion number is now printed.
                    954: 
                    955: */
                    956: /*
                    957:    Interpolated Markov Chain
                    958: 
                    959:   Short summary of the programme:
                    960:   
1.227     brouard   961:   This program computes Healthy Life Expectancies or State-specific
                    962:   (if states aren't health statuses) Expectancies from
                    963:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    964: 
                    965:   -1- a first survey ("cross") where individuals from different ages
                    966:   are interviewed on their health status or degree of disability (in
                    967:   the case of a health survey which is our main interest)
                    968: 
                    969:   -2- at least a second wave of interviews ("longitudinal") which
                    970:   measure each change (if any) in individual health status.  Health
                    971:   expectancies are computed from the time spent in each health state
                    972:   according to a model. More health states you consider, more time is
                    973:   necessary to reach the Maximum Likelihood of the parameters involved
                    974:   in the model.  The simplest model is the multinomial logistic model
                    975:   where pij is the probability to be observed in state j at the second
                    976:   wave conditional to be observed in state i at the first
                    977:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    978:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    979:   have a more complex model than "constant and age", you should modify
                    980:   the program where the markup *Covariates have to be included here
                    981:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   982:   convergence.
                    983: 
                    984:   The advantage of this computer programme, compared to a simple
                    985:   multinomial logistic model, is clear when the delay between waves is not
                    986:   identical for each individual. Also, if a individual missed an
                    987:   intermediate interview, the information is lost, but taken into
                    988:   account using an interpolation or extrapolation.  
                    989: 
                    990:   hPijx is the probability to be observed in state i at age x+h
                    991:   conditional to the observed state i at age x. The delay 'h' can be
                    992:   split into an exact number (nh*stepm) of unobserved intermediate
                    993:   states. This elementary transition (by month, quarter,
                    994:   semester or year) is modelled as a multinomial logistic.  The hPx
                    995:   matrix is simply the matrix product of nh*stepm elementary matrices
                    996:   and the contribution of each individual to the likelihood is simply
                    997:   hPijx.
                    998: 
                    999:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard  1000:   of the life expectancies. It also computes the period (stable) prevalence.
                   1001: 
                   1002: Back prevalence and projections:
1.227     brouard  1003: 
                   1004:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                   1005:    double agemaxpar, double ftolpl, int *ncvyearp, double
                   1006:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                   1007:    mobilavproj)
                   1008: 
                   1009:     Computes the back prevalence limit for any combination of
                   1010:     covariate values k at any age between ageminpar and agemaxpar and
                   1011:     returns it in **bprlim. In the loops,
                   1012: 
                   1013:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                   1014:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                   1015: 
                   1016:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard  1017:    Computes for any combination of covariates k and any age between bage and fage 
                   1018:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   1019:                        oldm=oldms;savm=savms;
1.227     brouard  1020: 
1.267     brouard  1021:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard  1022:      Computes the transition matrix starting at age 'age' over
                   1023:      'nhstepm*hstepm*stepm' months (i.e. until
                   1024:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard  1025:      nhstepm*hstepm matrices. 
                   1026: 
                   1027:      Returns p3mat[i][j][h] after calling
                   1028:      p3mat[i][j][h]=matprod2(newm,
                   1029:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                   1030:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                   1031:      oldm);
1.226     brouard  1032: 
                   1033: Important routines
                   1034: 
                   1035: - func (or funcone), computes logit (pij) distinguishing
                   1036:   o fixed variables (single or product dummies or quantitative);
                   1037:   o varying variables by:
                   1038:    (1) wave (single, product dummies, quantitative), 
                   1039:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                   1040:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                   1041:        % varying dummy (not done) or quantitative (not done);
                   1042: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                   1043:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                   1044: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                   1045:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                   1046:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard  1047: 
1.226     brouard  1048: 
                   1049:   
1.133     brouard  1050:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                   1051:            Institut national d'études démographiques, Paris.
1.126     brouard  1052:   This software have been partly granted by Euro-REVES, a concerted action
                   1053:   from the European Union.
                   1054:   It is copyrighted identically to a GNU software product, ie programme and
                   1055:   software can be distributed freely for non commercial use. Latest version
                   1056:   can be accessed at http://euroreves.ined.fr/imach .
                   1057: 
                   1058:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                   1059:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                   1060:   
                   1061:   **********************************************************************/
                   1062: /*
                   1063:   main
                   1064:   read parameterfile
                   1065:   read datafile
                   1066:   concatwav
                   1067:   freqsummary
                   1068:   if (mle >= 1)
                   1069:     mlikeli
                   1070:   print results files
                   1071:   if mle==1 
                   1072:      computes hessian
                   1073:   read end of parameter file: agemin, agemax, bage, fage, estepm
                   1074:       begin-prev-date,...
                   1075:   open gnuplot file
                   1076:   open html file
1.145     brouard  1077:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                   1078:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                   1079:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                   1080:     freexexit2 possible for memory heap.
                   1081: 
                   1082:   h Pij x                         | pij_nom  ficrestpij
                   1083:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                   1084:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                   1085:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                   1086: 
                   1087:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                   1088:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                   1089:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                   1090:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                   1091:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                   1092: 
1.126     brouard  1093:   forecasting if prevfcast==1 prevforecast call prevalence()
                   1094:   health expectancies
                   1095:   Variance-covariance of DFLE
                   1096:   prevalence()
                   1097:    movingaverage()
                   1098:   varevsij() 
                   1099:   if popbased==1 varevsij(,popbased)
                   1100:   total life expectancies
                   1101:   Variance of period (stable) prevalence
                   1102:  end
                   1103: */
                   1104: 
1.187     brouard  1105: /* #define DEBUG */
                   1106: /* #define DEBUGBRENT */
1.203     brouard  1107: /* #define DEBUGLINMIN */
                   1108: /* #define DEBUGHESS */
                   1109: #define DEBUGHESSIJ
1.224     brouard  1110: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard  1111: #define POWELL /* Instead of NLOPT */
1.224     brouard  1112: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard  1113: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                   1114: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.319     brouard  1115: /* #define FLATSUP  *//* Suppresses directions where likelihood is flat */
1.126     brouard  1116: 
                   1117: #include <math.h>
                   1118: #include <stdio.h>
                   1119: #include <stdlib.h>
                   1120: #include <string.h>
1.226     brouard  1121: #include <ctype.h>
1.159     brouard  1122: 
                   1123: #ifdef _WIN32
                   1124: #include <io.h>
1.172     brouard  1125: #include <windows.h>
                   1126: #include <tchar.h>
1.159     brouard  1127: #else
1.126     brouard  1128: #include <unistd.h>
1.159     brouard  1129: #endif
1.126     brouard  1130: 
                   1131: #include <limits.h>
                   1132: #include <sys/types.h>
1.171     brouard  1133: 
                   1134: #if defined(__GNUC__)
                   1135: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1136: #endif
                   1137: 
1.126     brouard  1138: #include <sys/stat.h>
                   1139: #include <errno.h>
1.159     brouard  1140: /* extern int errno; */
1.126     brouard  1141: 
1.157     brouard  1142: /* #ifdef LINUX */
                   1143: /* #include <time.h> */
                   1144: /* #include "timeval.h" */
                   1145: /* #else */
                   1146: /* #include <sys/time.h> */
                   1147: /* #endif */
                   1148: 
1.126     brouard  1149: #include <time.h>
                   1150: 
1.136     brouard  1151: #ifdef GSL
                   1152: #include <gsl/gsl_errno.h>
                   1153: #include <gsl/gsl_multimin.h>
                   1154: #endif
                   1155: 
1.167     brouard  1156: 
1.162     brouard  1157: #ifdef NLOPT
                   1158: #include <nlopt.h>
                   1159: typedef struct {
                   1160:   double (* function)(double [] );
                   1161: } myfunc_data ;
                   1162: #endif
                   1163: 
1.126     brouard  1164: /* #include <libintl.h> */
                   1165: /* #define _(String) gettext (String) */
                   1166: 
1.251     brouard  1167: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1168: 
                   1169: #define GNUPLOTPROGRAM "gnuplot"
                   1170: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1171: #define FILENAMELENGTH 132
                   1172: 
                   1173: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1174: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1175: 
1.144     brouard  1176: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1177: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1178: 
                   1179: #define NINTERVMAX 8
1.144     brouard  1180: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1181: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.318     brouard  1182: #define NCOVMAX 30  /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1183: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1184: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1185: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1186: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1187: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1188: /* #define AGESUP 130 */
1.288     brouard  1189: /* #define AGESUP 150 */
                   1190: #define AGESUP 200
1.268     brouard  1191: #define AGEINF 0
1.218     brouard  1192: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1193: #define AGEBASE 40
1.194     brouard  1194: #define AGEOVERFLOW 1.e20
1.164     brouard  1195: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1196: #ifdef _WIN32
                   1197: #define DIRSEPARATOR '\\'
                   1198: #define CHARSEPARATOR "\\"
                   1199: #define ODIRSEPARATOR '/'
                   1200: #else
1.126     brouard  1201: #define DIRSEPARATOR '/'
                   1202: #define CHARSEPARATOR "/"
                   1203: #define ODIRSEPARATOR '\\'
                   1204: #endif
                   1205: 
1.322   ! brouard  1206: /* $Id: imach.c,v 1.321 2022/07/22 12:04:24 brouard Exp $ */
1.126     brouard  1207: /* $State: Exp $ */
1.196     brouard  1208: #include "version.h"
                   1209: char version[]=__IMACH_VERSION__;
1.316     brouard  1210: char copyright[]="May 2022,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2020, Nihon University 2021-202, INED 2000-2022";
1.322   ! brouard  1211: char fullversion[]="$Revision: 1.321 $ $Date: 2022/07/22 12:04:24 $"; 
1.126     brouard  1212: char strstart[80];
                   1213: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1214: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1215: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1216: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1217: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1218: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1219: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1220: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1221: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1222: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1223: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1224: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1225: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1226: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1227: int nsd=0; /**< Total number of single dummy variables (output) */
                   1228: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1229: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1230: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1231: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1232: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1233: int cptcov=0; /* Working variable */
1.290     brouard  1234: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1235: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.302     brouard  1236: int npar=NPARMAX; /* Number of parameters (nlstate+ndeath-1)*nlstate*ncovmodel; */
1.126     brouard  1237: int nlstate=2; /* Number of live states */
                   1238: int ndeath=1; /* Number of dead states */
1.130     brouard  1239: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1240: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1241: int popbased=0;
                   1242: 
                   1243: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1244: int maxwav=0; /* Maxim number of waves */
                   1245: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1246: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1247: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1248:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1249: int mle=1, weightopt=0;
1.126     brouard  1250: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1251: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1252: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1253:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1254: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1255: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1256: 
1.130     brouard  1257: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1258: double **matprod2(); /* test */
1.126     brouard  1259: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1260: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1261: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1262: 
1.136     brouard  1263: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1264: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1265: FILE *ficlog, *ficrespow;
1.130     brouard  1266: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1267: double fretone; /* Only one call to likelihood */
1.130     brouard  1268: long ipmx=0; /* Number of contributions */
1.126     brouard  1269: double sw; /* Sum of weights */
                   1270: char filerespow[FILENAMELENGTH];
                   1271: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1272: FILE *ficresilk;
                   1273: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1274: FILE *ficresprobmorprev;
                   1275: FILE *fichtm, *fichtmcov; /* Html File */
                   1276: FILE *ficreseij;
                   1277: char filerese[FILENAMELENGTH];
                   1278: FILE *ficresstdeij;
                   1279: char fileresstde[FILENAMELENGTH];
                   1280: FILE *ficrescveij;
                   1281: char filerescve[FILENAMELENGTH];
                   1282: FILE  *ficresvij;
                   1283: char fileresv[FILENAMELENGTH];
1.269     brouard  1284: 
1.126     brouard  1285: char title[MAXLINE];
1.234     brouard  1286: char model[MAXLINE]; /**< The model line */
1.217     brouard  1287: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1288: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1289: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1290: char command[FILENAMELENGTH];
                   1291: int  outcmd=0;
                   1292: 
1.217     brouard  1293: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1294: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1295: char filelog[FILENAMELENGTH]; /* Log file */
                   1296: char filerest[FILENAMELENGTH];
                   1297: char fileregp[FILENAMELENGTH];
                   1298: char popfile[FILENAMELENGTH];
                   1299: 
                   1300: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1301: 
1.157     brouard  1302: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1303: /* struct timezone tzp; */
                   1304: /* extern int gettimeofday(); */
                   1305: struct tm tml, *gmtime(), *localtime();
                   1306: 
                   1307: extern time_t time();
                   1308: 
                   1309: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1310: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1311: struct tm tm;
                   1312: 
1.126     brouard  1313: char strcurr[80], strfor[80];
                   1314: 
                   1315: char *endptr;
                   1316: long lval;
                   1317: double dval;
                   1318: 
                   1319: #define NR_END 1
                   1320: #define FREE_ARG char*
                   1321: #define FTOL 1.0e-10
                   1322: 
                   1323: #define NRANSI 
1.240     brouard  1324: #define ITMAX 200
                   1325: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1326: 
                   1327: #define TOL 2.0e-4 
                   1328: 
                   1329: #define CGOLD 0.3819660 
                   1330: #define ZEPS 1.0e-10 
                   1331: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1332: 
                   1333: #define GOLD 1.618034 
                   1334: #define GLIMIT 100.0 
                   1335: #define TINY 1.0e-20 
                   1336: 
                   1337: static double maxarg1,maxarg2;
                   1338: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1339: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1340:   
                   1341: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1342: #define rint(a) floor(a+0.5)
1.166     brouard  1343: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1344: #define mytinydouble 1.0e-16
1.166     brouard  1345: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1346: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1347: /* static double dsqrarg; */
                   1348: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1349: static double sqrarg;
                   1350: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1351: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1352: int agegomp= AGEGOMP;
                   1353: 
                   1354: int imx; 
                   1355: int stepm=1;
                   1356: /* Stepm, step in month: minimum step interpolation*/
                   1357: 
                   1358: int estepm;
                   1359: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1360: 
                   1361: int m,nb;
                   1362: long *num;
1.197     brouard  1363: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1364: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1365:                   covariate for which somebody answered excluding 
                   1366:                   undefined. Usually 2: 0 and 1. */
                   1367: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1368:                             covariate for which somebody answered including 
                   1369:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1370: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1371: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1372: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1373: double *ageexmed,*agecens;
                   1374: double dateintmean=0;
1.296     brouard  1375:   double anprojd, mprojd, jprojd; /* For eventual projections */
                   1376:   double anprojf, mprojf, jprojf;
1.126     brouard  1377: 
1.296     brouard  1378:   double anbackd, mbackd, jbackd; /* For eventual backprojections */
                   1379:   double anbackf, mbackf, jbackf;
                   1380:   double jintmean,mintmean,aintmean;  
1.126     brouard  1381: double *weight;
                   1382: int **s; /* Status */
1.141     brouard  1383: double *agedc;
1.145     brouard  1384: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1385:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1386:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1387: double **coqvar; /* Fixed quantitative covariate nqv */
                   1388: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1389: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1390: double  idx; 
                   1391: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.319     brouard  1392: /* Some documentation */
                   1393:       /*   Design original data
                   1394:        *  V1   V2   V3   V4  V5  V6  V7  V8  Weight ddb ddth d1st s1 V9 V10 V11 V12 s2 V9 V10 V11 V12 
                   1395:        *  <          ncovcol=6   >   nqv=2 (V7 V8)                   dv dv  dv  qtv    dv dv  dvv qtv
                   1396:        *                                                             ntv=3     nqtv=1
                   1397:        *  cptcovn number of covariates (not including constant and age) = # of + plus 1 = 10+1=11
                   1398:        * For time varying covariate, quanti or dummies
                   1399:        *       cotqvar[wav][iv(1 to nqtv)][i]= [1][12][i]=(V12) quanti
                   1400:        *       cotvar[wav][ntv+iv][i]= [3+(1 to nqtv)][i]=(V12) quanti
                   1401:        *       cotvar[wav][iv(1 to ntv)][i]= [1][1][i]=(V9) dummies at wav 1
                   1402:        *       cotvar[wav][iv(1 to ntv)][i]= [1][2][i]=(V10) dummies at wav 1
                   1403:        *       covar[k,i], value of kth fixed covariate dummy or quanti :
                   1404:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   1405:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8 + V9 + V9*age + V10
                   1406:        *   k=  1    2      3       4     5       6      7        8   9     10       11 
                   1407:        */
                   1408: /* According to the model, more columns can be added to covar by the product of covariates */
1.318     brouard  1409: /* ncovcol=1(Males=0 Females=1) nqv=1(raedyrs) ntv=2(withoutiadl=0 withiadl=1, witoutadl=0 withoutadl=1) nqtv=1(bmi) nlstate=3 ndeath=1
                   1410:   # States 1=Coresidence, 2 Living alone, 3 Institution
                   1411:   # V1=sex, V2=raedyrs Quant Fixed, State=livarnb4..livarnb11, V3=iadl4..iald11, V4=adlw4..adlw11, V5=r4bmi..r11bmi
                   1412: */
1.319     brouard  1413: /*             V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1414: /*    k        1  2   3   4     5    6    7     8    9 */
                   1415: /*Typevar[k]=  0  0   0   2     1    0    2     1    0 *//*0 for simple covariate (dummy, quantitative,*/
                   1416:                                                          /* fixed or varying), 1 for age product, 2 for*/
                   1417:                                                          /* product */
                   1418: /*Dummy[k]=    1  0   0   1     3    1    1     2    0 *//*Dummy[k] 0=dummy (0 1), 1 quantitative */
                   1419:                                                          /*(single or product without age), 2 dummy*/
                   1420:                                                          /* with age product, 3 quant with age product*/
                   1421: /*Tvar[k]=     5  4   3   6     5    2    7     1    1 */
                   1422: /*    nsd         1   2                              3 */ /* Counting single dummies covar fixed or tv */
                   1423: /*TvarsD[nsd]     4   3                              1 */ /* ID of single dummy cova fixed or timevary*/
                   1424: /*TvarsDind[k]    2   3                              9 */ /* position K of single dummy cova */
                   1425: /*    nsq      1                     2                 */ /* Counting single quantit tv */
                   1426: /* TvarsQ[k]   5                     2                 */ /* Number of single quantitative cova */
                   1427: /* TvarsQind   1                     6                 */ /* position K of single quantitative cova */
                   1428: /* Tprod[i]=k             1               2            */ /* Position in model of the ith prod without age */
                   1429: /* cptcovage                    1               2      */ /* Counting cov*age in the model equation */
                   1430: /* Tage[cptcovage]=k            5               8      */ /* Position in the model of ith cov*age */
                   1431: /* Tvard[1][1]@4={4,3,1,2}    V4*V3 V1*V2              */ /* Position in model of the ith prod without age */
                   1432: /* TvarF TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  ID of fixed covariates or product V2, V1*V2, V1 */
1.320     brouard  1433: /* TvarFind;  TvarFind[1]=6,  TvarFind[2]=7, TvarFind[3]=9 *//* Inverse V2(6) is first fixed (single or prod)  */
1.234     brouard  1434: /* Type                    */
                   1435: /* V         1  2  3  4  5 */
                   1436: /*           F  F  V  V  V */
                   1437: /*           D  Q  D  D  Q */
                   1438: /*                         */
                   1439: int *TvarsD;
                   1440: int *TvarsDind;
                   1441: int *TvarsQ;
                   1442: int *TvarsQind;
                   1443: 
1.318     brouard  1444: #define MAXRESULTLINESPONE 10+1
1.235     brouard  1445: int nresult=0;
1.258     brouard  1446: int parameterline=0; /* # of the parameter (type) line */
1.318     brouard  1447: int TKresult[MAXRESULTLINESPONE];
                   1448: int Tresult[MAXRESULTLINESPONE][NCOVMAX];/* For dummy variable , value (output) */
                   1449: int Tinvresult[MAXRESULTLINESPONE][NCOVMAX];/* For dummy variable , value (output) */
                   1450: int Tvresult[MAXRESULTLINESPONE][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1451: double Tqresult[MAXRESULTLINESPONE][NCOVMAX]; /* For quantitative variable , value (output) */
                   1452: double Tqinvresult[MAXRESULTLINESPONE][NCOVMAX]; /* For quantitative variable , value (output) */
                   1453: int Tvqresult[MAXRESULTLINESPONE][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1454: 
                   1455: /* ncovcol=1(Males=0 Females=1) nqv=1(raedyrs) ntv=2(withoutiadl=0 withiadl=1, witoutadl=0 withoutadl=1) nqtv=1(bmi) nlstate=3 ndeath=1
                   1456:   # States 1=Coresidence, 2 Living alone, 3 Institution
                   1457:   # V1=sex, V2=raedyrs Quant Fixed, State=livarnb4..livarnb11, V3=iadl4..iald11, V4=adlw4..adlw11, V5=r4bmi..r11bmi
                   1458: */
1.234     brouard  1459: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1460: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1461: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1462: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1463: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1464: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1465: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1466: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1467: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1468: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1469: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1470: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1471: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1472: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1473: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1474: 
1.230     brouard  1475: int *Tvarsel; /**< Selected covariates for output */
                   1476: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1477: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1478: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1479: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1480: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1481: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1482: int *Tage;
1.227     brouard  1483: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1484: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1485: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1486: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1487: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1488: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1489: int **Tvard;
                   1490: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1491: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1492: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1493:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1494:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1495: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1496: double *lsurv, *lpop, *tpop;
                   1497: 
1.231     brouard  1498: #define FD 1; /* Fixed dummy covariate */
                   1499: #define FQ 2; /* Fixed quantitative covariate */
                   1500: #define FP 3; /* Fixed product covariate */
                   1501: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1502: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1503: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1504: #define VD 10; /* Varying dummy covariate */
                   1505: #define VQ 11; /* Varying quantitative covariate */
                   1506: #define VP 12; /* Varying product covariate */
                   1507: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1508: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1509: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1510: #define APFD 16; /* Age product * fixed dummy covariate */
                   1511: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1512: #define APVD 18; /* Age product * varying dummy covariate */
                   1513: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1514: 
                   1515: #define FTYPE 1; /* Fixed covariate */
                   1516: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1517: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1518: 
                   1519: struct kmodel{
                   1520:        int maintype; /* main type */
                   1521:        int subtype; /* subtype */
                   1522: };
                   1523: struct kmodel modell[NCOVMAX];
                   1524: 
1.143     brouard  1525: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1526: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1527: 
                   1528: /**************** split *************************/
                   1529: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1530: {
                   1531:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1532:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1533:   */ 
                   1534:   char *ss;                            /* pointer */
1.186     brouard  1535:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1536: 
                   1537:   l1 = strlen(path );                  /* length of path */
                   1538:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1539:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1540:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1541:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1542:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1543:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1544:     /* get current working directory */
                   1545:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1546: #ifdef WIN32
                   1547:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1548: #else
                   1549:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1550: #endif
1.126     brouard  1551:       return( GLOCK_ERROR_GETCWD );
                   1552:     }
                   1553:     /* got dirc from getcwd*/
                   1554:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1555:   } else {                             /* strip directory from path */
1.126     brouard  1556:     ss++;                              /* after this, the filename */
                   1557:     l2 = strlen( ss );                 /* length of filename */
                   1558:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1559:     strcpy( name, ss );                /* save file name */
                   1560:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1561:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1562:     printf(" DIRC2 = %s \n",dirc);
                   1563:   }
                   1564:   /* We add a separator at the end of dirc if not exists */
                   1565:   l1 = strlen( dirc );                 /* length of directory */
                   1566:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1567:     dirc[l1] =  DIRSEPARATOR;
                   1568:     dirc[l1+1] = 0; 
                   1569:     printf(" DIRC3 = %s \n",dirc);
                   1570:   }
                   1571:   ss = strrchr( name, '.' );           /* find last / */
                   1572:   if (ss >0){
                   1573:     ss++;
                   1574:     strcpy(ext,ss);                    /* save extension */
                   1575:     l1= strlen( name);
                   1576:     l2= strlen(ss)+1;
                   1577:     strncpy( finame, name, l1-l2);
                   1578:     finame[l1-l2]= 0;
                   1579:   }
                   1580: 
                   1581:   return( 0 );                         /* we're done */
                   1582: }
                   1583: 
                   1584: 
                   1585: /******************************************/
                   1586: 
                   1587: void replace_back_to_slash(char *s, char*t)
                   1588: {
                   1589:   int i;
                   1590:   int lg=0;
                   1591:   i=0;
                   1592:   lg=strlen(t);
                   1593:   for(i=0; i<= lg; i++) {
                   1594:     (s[i] = t[i]);
                   1595:     if (t[i]== '\\') s[i]='/';
                   1596:   }
                   1597: }
                   1598: 
1.132     brouard  1599: char *trimbb(char *out, char *in)
1.137     brouard  1600: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1601:   char *s;
                   1602:   s=out;
                   1603:   while (*in != '\0'){
1.137     brouard  1604:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1605:       in++;
                   1606:     }
                   1607:     *out++ = *in++;
                   1608:   }
                   1609:   *out='\0';
                   1610:   return s;
                   1611: }
                   1612: 
1.187     brouard  1613: /* char *substrchaine(char *out, char *in, char *chain) */
                   1614: /* { */
                   1615: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1616: /*   char *s, *t; */
                   1617: /*   t=in;s=out; */
                   1618: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1619: /*     *out++ = *in++; */
                   1620: /*   } */
                   1621: 
                   1622: /*   /\* *in matches *chain *\/ */
                   1623: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1624: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1625: /*   } */
                   1626: /*   in--; chain--; */
                   1627: /*   while ( (*in != '\0')){ */
                   1628: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1629: /*     *out++ = *in++; */
                   1630: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1631: /*   } */
                   1632: /*   *out='\0'; */
                   1633: /*   out=s; */
                   1634: /*   return out; */
                   1635: /* } */
                   1636: char *substrchaine(char *out, char *in, char *chain)
                   1637: {
                   1638:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1639:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1640: 
                   1641:   char *strloc;
                   1642: 
                   1643:   strcpy (out, in); 
                   1644:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1645:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1646:   if(strloc != NULL){ 
                   1647:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1648:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1649:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1650:   }
                   1651:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1652:   return out;
                   1653: }
                   1654: 
                   1655: 
1.145     brouard  1656: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1657: {
1.187     brouard  1658:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1659:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.310     brouard  1660:      gives alocc="abcdef" and blocc="ghi2j".
1.145     brouard  1661:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1662:   */
1.160     brouard  1663:   char *s, *t;
1.145     brouard  1664:   t=in;s=in;
                   1665:   while ((*in != occ) && (*in != '\0')){
                   1666:     *alocc++ = *in++;
                   1667:   }
                   1668:   if( *in == occ){
                   1669:     *(alocc)='\0';
                   1670:     s=++in;
                   1671:   }
                   1672:  
                   1673:   if (s == t) {/* occ not found */
                   1674:     *(alocc-(in-s))='\0';
                   1675:     in=s;
                   1676:   }
                   1677:   while ( *in != '\0'){
                   1678:     *blocc++ = *in++;
                   1679:   }
                   1680: 
                   1681:   *blocc='\0';
                   1682:   return t;
                   1683: }
1.137     brouard  1684: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1685: {
1.187     brouard  1686:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1687:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1688:      gives blocc="abcdef2ghi" and alocc="j".
                   1689:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1690:   */
                   1691:   char *s, *t;
                   1692:   t=in;s=in;
                   1693:   while (*in != '\0'){
                   1694:     while( *in == occ){
                   1695:       *blocc++ = *in++;
                   1696:       s=in;
                   1697:     }
                   1698:     *blocc++ = *in++;
                   1699:   }
                   1700:   if (s == t) /* occ not found */
                   1701:     *(blocc-(in-s))='\0';
                   1702:   else
                   1703:     *(blocc-(in-s)-1)='\0';
                   1704:   in=s;
                   1705:   while ( *in != '\0'){
                   1706:     *alocc++ = *in++;
                   1707:   }
                   1708: 
                   1709:   *alocc='\0';
                   1710:   return s;
                   1711: }
                   1712: 
1.126     brouard  1713: int nbocc(char *s, char occ)
                   1714: {
                   1715:   int i,j=0;
                   1716:   int lg=20;
                   1717:   i=0;
                   1718:   lg=strlen(s);
                   1719:   for(i=0; i<= lg; i++) {
1.234     brouard  1720:     if  (s[i] == occ ) j++;
1.126     brouard  1721:   }
                   1722:   return j;
                   1723: }
                   1724: 
1.137     brouard  1725: /* void cutv(char *u,char *v, char*t, char occ) */
                   1726: /* { */
                   1727: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1728: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1729: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1730: /*   int i,lg,j,p=0; */
                   1731: /*   i=0; */
                   1732: /*   lg=strlen(t); */
                   1733: /*   for(j=0; j<=lg-1; j++) { */
                   1734: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1735: /*   } */
1.126     brouard  1736: 
1.137     brouard  1737: /*   for(j=0; j<p; j++) { */
                   1738: /*     (u[j] = t[j]); */
                   1739: /*   } */
                   1740: /*      u[p]='\0'; */
1.126     brouard  1741: 
1.137     brouard  1742: /*    for(j=0; j<= lg; j++) { */
                   1743: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1744: /*   } */
                   1745: /* } */
1.126     brouard  1746: 
1.160     brouard  1747: #ifdef _WIN32
                   1748: char * strsep(char **pp, const char *delim)
                   1749: {
                   1750:   char *p, *q;
                   1751:          
                   1752:   if ((p = *pp) == NULL)
                   1753:     return 0;
                   1754:   if ((q = strpbrk (p, delim)) != NULL)
                   1755:   {
                   1756:     *pp = q + 1;
                   1757:     *q = '\0';
                   1758:   }
                   1759:   else
                   1760:     *pp = 0;
                   1761:   return p;
                   1762: }
                   1763: #endif
                   1764: 
1.126     brouard  1765: /********************** nrerror ********************/
                   1766: 
                   1767: void nrerror(char error_text[])
                   1768: {
                   1769:   fprintf(stderr,"ERREUR ...\n");
                   1770:   fprintf(stderr,"%s\n",error_text);
                   1771:   exit(EXIT_FAILURE);
                   1772: }
                   1773: /*********************** vector *******************/
                   1774: double *vector(int nl, int nh)
                   1775: {
                   1776:   double *v;
                   1777:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1778:   if (!v) nrerror("allocation failure in vector");
                   1779:   return v-nl+NR_END;
                   1780: }
                   1781: 
                   1782: /************************ free vector ******************/
                   1783: void free_vector(double*v, int nl, int nh)
                   1784: {
                   1785:   free((FREE_ARG)(v+nl-NR_END));
                   1786: }
                   1787: 
                   1788: /************************ivector *******************************/
                   1789: int *ivector(long nl,long nh)
                   1790: {
                   1791:   int *v;
                   1792:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1793:   if (!v) nrerror("allocation failure in ivector");
                   1794:   return v-nl+NR_END;
                   1795: }
                   1796: 
                   1797: /******************free ivector **************************/
                   1798: void free_ivector(int *v, long nl, long nh)
                   1799: {
                   1800:   free((FREE_ARG)(v+nl-NR_END));
                   1801: }
                   1802: 
                   1803: /************************lvector *******************************/
                   1804: long *lvector(long nl,long nh)
                   1805: {
                   1806:   long *v;
                   1807:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1808:   if (!v) nrerror("allocation failure in ivector");
                   1809:   return v-nl+NR_END;
                   1810: }
                   1811: 
                   1812: /******************free lvector **************************/
                   1813: void free_lvector(long *v, long nl, long nh)
                   1814: {
                   1815:   free((FREE_ARG)(v+nl-NR_END));
                   1816: }
                   1817: 
                   1818: /******************* imatrix *******************************/
                   1819: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1820:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1821: { 
                   1822:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1823:   int **m; 
                   1824:   
                   1825:   /* allocate pointers to rows */ 
                   1826:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1827:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1828:   m += NR_END; 
                   1829:   m -= nrl; 
                   1830:   
                   1831:   
                   1832:   /* allocate rows and set pointers to them */ 
                   1833:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1834:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1835:   m[nrl] += NR_END; 
                   1836:   m[nrl] -= ncl; 
                   1837:   
                   1838:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1839:   
                   1840:   /* return pointer to array of pointers to rows */ 
                   1841:   return m; 
                   1842: } 
                   1843: 
                   1844: /****************** free_imatrix *************************/
                   1845: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1846:       int **m;
                   1847:       long nch,ncl,nrh,nrl; 
                   1848:      /* free an int matrix allocated by imatrix() */ 
                   1849: { 
                   1850:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1851:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1852: } 
                   1853: 
                   1854: /******************* matrix *******************************/
                   1855: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1856: {
                   1857:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1858:   double **m;
                   1859: 
                   1860:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1861:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1862:   m += NR_END;
                   1863:   m -= nrl;
                   1864: 
                   1865:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1866:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1867:   m[nrl] += NR_END;
                   1868:   m[nrl] -= ncl;
                   1869: 
                   1870:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1871:   return m;
1.145     brouard  1872:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1873: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1874: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1875:    */
                   1876: }
                   1877: 
                   1878: /*************************free matrix ************************/
                   1879: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1880: {
                   1881:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1882:   free((FREE_ARG)(m+nrl-NR_END));
                   1883: }
                   1884: 
                   1885: /******************* ma3x *******************************/
                   1886: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1887: {
                   1888:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1889:   double ***m;
                   1890: 
                   1891:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1892:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1893:   m += NR_END;
                   1894:   m -= nrl;
                   1895: 
                   1896:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1897:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1898:   m[nrl] += NR_END;
                   1899:   m[nrl] -= ncl;
                   1900: 
                   1901:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1902: 
                   1903:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1904:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1905:   m[nrl][ncl] += NR_END;
                   1906:   m[nrl][ncl] -= nll;
                   1907:   for (j=ncl+1; j<=nch; j++) 
                   1908:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1909:   
                   1910:   for (i=nrl+1; i<=nrh; i++) {
                   1911:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1912:     for (j=ncl+1; j<=nch; j++) 
                   1913:       m[i][j]=m[i][j-1]+nlay;
                   1914:   }
                   1915:   return m; 
                   1916:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1917:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1918:   */
                   1919: }
                   1920: 
                   1921: /*************************free ma3x ************************/
                   1922: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1923: {
                   1924:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1925:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1926:   free((FREE_ARG)(m+nrl-NR_END));
                   1927: }
                   1928: 
                   1929: /*************** function subdirf ***********/
                   1930: char *subdirf(char fileres[])
                   1931: {
                   1932:   /* Caution optionfilefiname is hidden */
                   1933:   strcpy(tmpout,optionfilefiname);
                   1934:   strcat(tmpout,"/"); /* Add to the right */
                   1935:   strcat(tmpout,fileres);
                   1936:   return tmpout;
                   1937: }
                   1938: 
                   1939: /*************** function subdirf2 ***********/
                   1940: char *subdirf2(char fileres[], char *preop)
                   1941: {
1.314     brouard  1942:   /* Example subdirf2(optionfilefiname,"FB_") with optionfilefiname="texte", result="texte/FB_texte"
                   1943:  Errors in subdirf, 2, 3 while printing tmpout is
1.315     brouard  1944:  rewritten within the same printf. Workaround: many printfs */
1.126     brouard  1945:   /* Caution optionfilefiname is hidden */
                   1946:   strcpy(tmpout,optionfilefiname);
                   1947:   strcat(tmpout,"/");
                   1948:   strcat(tmpout,preop);
                   1949:   strcat(tmpout,fileres);
                   1950:   return tmpout;
                   1951: }
                   1952: 
                   1953: /*************** function subdirf3 ***********/
                   1954: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1955: {
                   1956:   
                   1957:   /* Caution optionfilefiname is hidden */
                   1958:   strcpy(tmpout,optionfilefiname);
                   1959:   strcat(tmpout,"/");
                   1960:   strcat(tmpout,preop);
                   1961:   strcat(tmpout,preop2);
                   1962:   strcat(tmpout,fileres);
                   1963:   return tmpout;
                   1964: }
1.213     brouard  1965:  
                   1966: /*************** function subdirfext ***********/
                   1967: char *subdirfext(char fileres[], char *preop, char *postop)
                   1968: {
                   1969:   
                   1970:   strcpy(tmpout,preop);
                   1971:   strcat(tmpout,fileres);
                   1972:   strcat(tmpout,postop);
                   1973:   return tmpout;
                   1974: }
1.126     brouard  1975: 
1.213     brouard  1976: /*************** function subdirfext3 ***********/
                   1977: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1978: {
                   1979:   
                   1980:   /* Caution optionfilefiname is hidden */
                   1981:   strcpy(tmpout,optionfilefiname);
                   1982:   strcat(tmpout,"/");
                   1983:   strcat(tmpout,preop);
                   1984:   strcat(tmpout,fileres);
                   1985:   strcat(tmpout,postop);
                   1986:   return tmpout;
                   1987: }
                   1988:  
1.162     brouard  1989: char *asc_diff_time(long time_sec, char ascdiff[])
                   1990: {
                   1991:   long sec_left, days, hours, minutes;
                   1992:   days = (time_sec) / (60*60*24);
                   1993:   sec_left = (time_sec) % (60*60*24);
                   1994:   hours = (sec_left) / (60*60) ;
                   1995:   sec_left = (sec_left) %(60*60);
                   1996:   minutes = (sec_left) /60;
                   1997:   sec_left = (sec_left) % (60);
                   1998:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1999:   return ascdiff;
                   2000: }
                   2001: 
1.126     brouard  2002: /***************** f1dim *************************/
                   2003: extern int ncom; 
                   2004: extern double *pcom,*xicom;
                   2005: extern double (*nrfunc)(double []); 
                   2006:  
                   2007: double f1dim(double x) 
                   2008: { 
                   2009:   int j; 
                   2010:   double f;
                   2011:   double *xt; 
                   2012:  
                   2013:   xt=vector(1,ncom); 
                   2014:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   2015:   f=(*nrfunc)(xt); 
                   2016:   free_vector(xt,1,ncom); 
                   2017:   return f; 
                   2018: } 
                   2019: 
                   2020: /*****************brent *************************/
                   2021: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  2022: {
                   2023:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   2024:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   2025:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   2026:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   2027:    * returned function value. 
                   2028:   */
1.126     brouard  2029:   int iter; 
                   2030:   double a,b,d,etemp;
1.159     brouard  2031:   double fu=0,fv,fw,fx;
1.164     brouard  2032:   double ftemp=0.;
1.126     brouard  2033:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   2034:   double e=0.0; 
                   2035:  
                   2036:   a=(ax < cx ? ax : cx); 
                   2037:   b=(ax > cx ? ax : cx); 
                   2038:   x=w=v=bx; 
                   2039:   fw=fv=fx=(*f)(x); 
                   2040:   for (iter=1;iter<=ITMAX;iter++) { 
                   2041:     xm=0.5*(a+b); 
                   2042:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   2043:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   2044:     printf(".");fflush(stdout);
                   2045:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  2046: #ifdef DEBUGBRENT
1.126     brouard  2047:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   2048:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   2049:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   2050: #endif
                   2051:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   2052:       *xmin=x; 
                   2053:       return fx; 
                   2054:     } 
                   2055:     ftemp=fu;
                   2056:     if (fabs(e) > tol1) { 
                   2057:       r=(x-w)*(fx-fv); 
                   2058:       q=(x-v)*(fx-fw); 
                   2059:       p=(x-v)*q-(x-w)*r; 
                   2060:       q=2.0*(q-r); 
                   2061:       if (q > 0.0) p = -p; 
                   2062:       q=fabs(q); 
                   2063:       etemp=e; 
                   2064:       e=d; 
                   2065:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  2066:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  2067:       else { 
1.224     brouard  2068:                                d=p/q; 
                   2069:                                u=x+d; 
                   2070:                                if (u-a < tol2 || b-u < tol2) 
                   2071:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  2072:       } 
                   2073:     } else { 
                   2074:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   2075:     } 
                   2076:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   2077:     fu=(*f)(u); 
                   2078:     if (fu <= fx) { 
                   2079:       if (u >= x) a=x; else b=x; 
                   2080:       SHFT(v,w,x,u) 
1.183     brouard  2081:       SHFT(fv,fw,fx,fu) 
                   2082:     } else { 
                   2083:       if (u < x) a=u; else b=u; 
                   2084:       if (fu <= fw || w == x) { 
1.224     brouard  2085:                                v=w; 
                   2086:                                w=u; 
                   2087:                                fv=fw; 
                   2088:                                fw=fu; 
1.183     brouard  2089:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  2090:                                v=u; 
                   2091:                                fv=fu; 
1.183     brouard  2092:       } 
                   2093:     } 
1.126     brouard  2094:   } 
                   2095:   nrerror("Too many iterations in brent"); 
                   2096:   *xmin=x; 
                   2097:   return fx; 
                   2098: } 
                   2099: 
                   2100: /****************** mnbrak ***********************/
                   2101: 
                   2102: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   2103:            double (*func)(double)) 
1.183     brouard  2104: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   2105: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   2106: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   2107: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   2108:    */
1.126     brouard  2109:   double ulim,u,r,q, dum;
                   2110:   double fu; 
1.187     brouard  2111: 
                   2112:   double scale=10.;
                   2113:   int iterscale=0;
                   2114: 
                   2115:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   2116:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   2117: 
                   2118: 
                   2119:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   2120:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   2121:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   2122:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   2123:   /* } */
                   2124: 
1.126     brouard  2125:   if (*fb > *fa) { 
                   2126:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  2127:     SHFT(dum,*fb,*fa,dum) 
                   2128:   } 
1.126     brouard  2129:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   2130:   *fc=(*func)(*cx); 
1.183     brouard  2131: #ifdef DEBUG
1.224     brouard  2132:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   2133:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  2134: #endif
1.224     brouard  2135:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  2136:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  2137:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  2138:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  2139:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   2140:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   2141:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  2142:       fu=(*func)(u); 
1.163     brouard  2143: #ifdef DEBUG
                   2144:       /* f(x)=A(x-u)**2+f(u) */
                   2145:       double A, fparabu; 
                   2146:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2147:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  2148:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   2149:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  2150:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   2151:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   2152:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   2153:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  2154: #endif 
1.184     brouard  2155: #ifdef MNBRAKORIGINAL
1.183     brouard  2156: #else
1.191     brouard  2157: /*       if (fu > *fc) { */
                   2158: /* #ifdef DEBUG */
                   2159: /*       printf("mnbrak4  fu > fc \n"); */
                   2160: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   2161: /* #endif */
                   2162: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   2163: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   2164: /*     dum=u; /\* Shifting c and u *\/ */
                   2165: /*     u = *cx; */
                   2166: /*     *cx = dum; */
                   2167: /*     dum = fu; */
                   2168: /*     fu = *fc; */
                   2169: /*     *fc =dum; */
                   2170: /*       } else { /\* end *\/ */
                   2171: /* #ifdef DEBUG */
                   2172: /*       printf("mnbrak3  fu < fc \n"); */
                   2173: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2174: /* #endif */
                   2175: /*     dum=u; /\* Shifting c and u *\/ */
                   2176: /*     u = *cx; */
                   2177: /*     *cx = dum; */
                   2178: /*     dum = fu; */
                   2179: /*     fu = *fc; */
                   2180: /*     *fc =dum; */
                   2181: /*       } */
1.224     brouard  2182: #ifdef DEBUGMNBRAK
                   2183:                 double A, fparabu; 
                   2184:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2185:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2186:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2187:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2188: #endif
1.191     brouard  2189:       dum=u; /* Shifting c and u */
                   2190:       u = *cx;
                   2191:       *cx = dum;
                   2192:       dum = fu;
                   2193:       fu = *fc;
                   2194:       *fc =dum;
1.183     brouard  2195: #endif
1.162     brouard  2196:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2197: #ifdef DEBUG
1.224     brouard  2198:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2199:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2200: #endif
1.126     brouard  2201:       fu=(*func)(u); 
                   2202:       if (fu < *fc) { 
1.183     brouard  2203: #ifdef DEBUG
1.224     brouard  2204:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2205:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2206: #endif
                   2207:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2208:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2209: #ifdef DEBUG
                   2210:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2211: #endif
                   2212:       } 
1.162     brouard  2213:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2214: #ifdef DEBUG
1.224     brouard  2215:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2216:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2217: #endif
1.126     brouard  2218:       u=ulim; 
                   2219:       fu=(*func)(u); 
1.183     brouard  2220:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2221: #ifdef DEBUG
1.224     brouard  2222:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2223:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2224: #endif
1.126     brouard  2225:       u=(*cx)+GOLD*(*cx-*bx); 
                   2226:       fu=(*func)(u); 
1.224     brouard  2227: #ifdef DEBUG
                   2228:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2229:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2230: #endif
1.183     brouard  2231:     } /* end tests */
1.126     brouard  2232:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2233:     SHFT(*fa,*fb,*fc,fu) 
                   2234: #ifdef DEBUG
1.224     brouard  2235:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2236:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2237: #endif
                   2238:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2239: } 
                   2240: 
                   2241: /*************** linmin ************************/
1.162     brouard  2242: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2243: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2244: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2245: the value of func at the returned location p . This is actually all accomplished by calling the
                   2246: routines mnbrak and brent .*/
1.126     brouard  2247: int ncom; 
                   2248: double *pcom,*xicom;
                   2249: double (*nrfunc)(double []); 
                   2250:  
1.224     brouard  2251: #ifdef LINMINORIGINAL
1.126     brouard  2252: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2253: #else
                   2254: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2255: #endif
1.126     brouard  2256: { 
                   2257:   double brent(double ax, double bx, double cx, 
                   2258:               double (*f)(double), double tol, double *xmin); 
                   2259:   double f1dim(double x); 
                   2260:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2261:              double *fc, double (*func)(double)); 
                   2262:   int j; 
                   2263:   double xx,xmin,bx,ax; 
                   2264:   double fx,fb,fa;
1.187     brouard  2265: 
1.203     brouard  2266: #ifdef LINMINORIGINAL
                   2267: #else
                   2268:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2269: #endif
                   2270:   
1.126     brouard  2271:   ncom=n; 
                   2272:   pcom=vector(1,n); 
                   2273:   xicom=vector(1,n); 
                   2274:   nrfunc=func; 
                   2275:   for (j=1;j<=n;j++) { 
                   2276:     pcom[j]=p[j]; 
1.202     brouard  2277:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2278:   } 
1.187     brouard  2279: 
1.203     brouard  2280: #ifdef LINMINORIGINAL
                   2281:   xx=1.;
                   2282: #else
                   2283:   axs=0.0;
                   2284:   xxs=1.;
                   2285:   do{
                   2286:     xx= xxs;
                   2287: #endif
1.187     brouard  2288:     ax=0.;
                   2289:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2290:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2291:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2292:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2293:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2294:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2295:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2296: #ifdef LINMINORIGINAL
                   2297: #else
                   2298:     if (fx != fx){
1.224     brouard  2299:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2300:                        printf("|");
                   2301:                        fprintf(ficlog,"|");
1.203     brouard  2302: #ifdef DEBUGLINMIN
1.224     brouard  2303:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2304: #endif
                   2305:     }
1.224     brouard  2306:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2307: #endif
                   2308:   
1.191     brouard  2309: #ifdef DEBUGLINMIN
                   2310:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2311:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2312: #endif
1.224     brouard  2313: #ifdef LINMINORIGINAL
                   2314: #else
1.317     brouard  2315:   if(fb == fx){ /* Flat function in the direction */
                   2316:     xmin=xx;
1.224     brouard  2317:     *flat=1;
1.317     brouard  2318:   }else{
1.224     brouard  2319:     *flat=0;
                   2320: #endif
                   2321:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2322:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2323:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2324:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2325:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2326:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2327: #ifdef DEBUG
1.224     brouard  2328:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2329:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2330: #endif
                   2331: #ifdef LINMINORIGINAL
                   2332: #else
                   2333:                        }
1.126     brouard  2334: #endif
1.191     brouard  2335: #ifdef DEBUGLINMIN
                   2336:   printf("linmin end ");
1.202     brouard  2337:   fprintf(ficlog,"linmin end ");
1.191     brouard  2338: #endif
1.126     brouard  2339:   for (j=1;j<=n;j++) { 
1.203     brouard  2340: #ifdef LINMINORIGINAL
                   2341:     xi[j] *= xmin; 
                   2342: #else
                   2343: #ifdef DEBUGLINMIN
                   2344:     if(xxs <1.0)
                   2345:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2346: #endif
                   2347:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2348: #ifdef DEBUGLINMIN
                   2349:     if(xxs <1.0)
                   2350:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2351: #endif
                   2352: #endif
1.187     brouard  2353:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2354:   } 
1.191     brouard  2355: #ifdef DEBUGLINMIN
1.203     brouard  2356:   printf("\n");
1.191     brouard  2357:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2358:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2359:   for (j=1;j<=n;j++) { 
1.202     brouard  2360:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2361:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2362:     if(j % ncovmodel == 0){
1.191     brouard  2363:       printf("\n");
1.202     brouard  2364:       fprintf(ficlog,"\n");
                   2365:     }
1.191     brouard  2366:   }
1.203     brouard  2367: #else
1.191     brouard  2368: #endif
1.126     brouard  2369:   free_vector(xicom,1,n); 
                   2370:   free_vector(pcom,1,n); 
                   2371: } 
                   2372: 
                   2373: 
                   2374: /*************** powell ************************/
1.162     brouard  2375: /*
1.317     brouard  2376: Minimization of a function func of n variables. Input consists in an initial starting point
                   2377: p[1..n] ; an initial matrix xi[1..n][1..n]  whose columns contain the initial set of di-
                   2378: rections (usually the n unit vectors); and ftol, the fractional tolerance in the function value
                   2379: such that failure to decrease by more than this amount in one iteration signals doneness. On
1.162     brouard  2380: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2381: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2382:  */
1.224     brouard  2383: #ifdef LINMINORIGINAL
                   2384: #else
                   2385:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2386:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2387: #endif
1.126     brouard  2388: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2389:            double (*func)(double [])) 
                   2390: { 
1.224     brouard  2391: #ifdef LINMINORIGINAL
                   2392:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2393:              double (*func)(double [])); 
1.224     brouard  2394: #else 
1.241     brouard  2395:  void linmin(double p[], double xi[], int n, double *fret,
                   2396:             double (*func)(double []),int *flat); 
1.224     brouard  2397: #endif
1.239     brouard  2398:  int i,ibig,j,jk,k; 
1.126     brouard  2399:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2400:   double directest;
1.126     brouard  2401:   double fp,fptt;
                   2402:   double *xits;
                   2403:   int niterf, itmp;
                   2404: 
                   2405:   pt=vector(1,n); 
                   2406:   ptt=vector(1,n); 
                   2407:   xit=vector(1,n); 
                   2408:   xits=vector(1,n); 
                   2409:   *fret=(*func)(p); 
                   2410:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2411:   rcurr_time = time(NULL);  
1.126     brouard  2412:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2413:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2414:     ibig=0; 
                   2415:     del=0.0; 
1.157     brouard  2416:     rlast_time=rcurr_time;
                   2417:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2418:     rcurr_time = time(NULL);  
                   2419:     curr_time = *localtime(&rcurr_time);
                   2420:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2421:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2422: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2423:     for (i=1;i<=n;i++) {
1.126     brouard  2424:       fprintf(ficrespow," %.12lf", p[i]);
                   2425:     }
1.239     brouard  2426:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2427:     printf("\n#model=  1      +     age ");
                   2428:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2429:     if(nagesqr==1){
1.241     brouard  2430:        printf("  + age*age  ");
                   2431:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2432:     }
                   2433:     for(j=1;j <=ncovmodel-2;j++){
                   2434:       if(Typevar[j]==0) {
                   2435:        printf("  +      V%d  ",Tvar[j]);
                   2436:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2437:       }else if(Typevar[j]==1) {
                   2438:        printf("  +    V%d*age ",Tvar[j]);
                   2439:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2440:       }else if(Typevar[j]==2) {
                   2441:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2442:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2443:       }
                   2444:     }
1.126     brouard  2445:     printf("\n");
1.239     brouard  2446: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2447: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2448:     fprintf(ficlog,"\n");
1.239     brouard  2449:     for(i=1,jk=1; i <=nlstate; i++){
                   2450:       for(k=1; k <=(nlstate+ndeath); k++){
                   2451:        if (k != i) {
                   2452:          printf("%d%d ",i,k);
                   2453:          fprintf(ficlog,"%d%d ",i,k);
                   2454:          for(j=1; j <=ncovmodel; j++){
                   2455:            printf("%12.7f ",p[jk]);
                   2456:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2457:            jk++; 
                   2458:          }
                   2459:          printf("\n");
                   2460:          fprintf(ficlog,"\n");
                   2461:        }
                   2462:       }
                   2463:     }
1.241     brouard  2464:     if(*iter <=3 && *iter >1){
1.157     brouard  2465:       tml = *localtime(&rcurr_time);
                   2466:       strcpy(strcurr,asctime(&tml));
                   2467:       rforecast_time=rcurr_time; 
1.126     brouard  2468:       itmp = strlen(strcurr);
                   2469:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2470:        strcurr[itmp-1]='\0';
1.162     brouard  2471:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2472:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2473:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2474:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2475:        forecast_time = *localtime(&rforecast_time);
                   2476:        strcpy(strfor,asctime(&forecast_time));
                   2477:        itmp = strlen(strfor);
                   2478:        if(strfor[itmp-1]=='\n')
                   2479:          strfor[itmp-1]='\0';
                   2480:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2481:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2482:       }
                   2483:     }
1.187     brouard  2484:     for (i=1;i<=n;i++) { /* For each direction i */
                   2485:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2486:       fptt=(*fret); 
                   2487: #ifdef DEBUG
1.203     brouard  2488:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2489:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2490: #endif
1.203     brouard  2491:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2492:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2493: #ifdef LINMINORIGINAL
1.188     brouard  2494:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2495: #else
                   2496:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2497:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2498: #endif
                   2499:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2500:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2501:                                /* because that direction will be replaced unless the gain del is small */
                   2502:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2503:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2504:                                /* with the new direction. */
                   2505:                                del=fabs(fptt-(*fret)); 
                   2506:                                ibig=i; 
1.126     brouard  2507:       } 
                   2508: #ifdef DEBUG
                   2509:       printf("%d %.12e",i,(*fret));
                   2510:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2511:       for (j=1;j<=n;j++) {
1.224     brouard  2512:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2513:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2514:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2515:       }
                   2516:       for(j=1;j<=n;j++) {
1.225     brouard  2517:                                printf(" p(%d)=%.12e",j,p[j]);
                   2518:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2519:       }
                   2520:       printf("\n");
                   2521:       fprintf(ficlog,"\n");
                   2522: #endif
1.187     brouard  2523:     } /* end loop on each direction i */
                   2524:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2525:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2526:     /* New value of last point Pn is not computed, P(n-1) */
1.319     brouard  2527:     for(j=1;j<=n;j++) {
                   2528:       if(flatdir[j] >0){
                   2529:         printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2530:         fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
1.302     brouard  2531:       }
1.319     brouard  2532:       /* printf("\n"); */
                   2533:       /* fprintf(ficlog,"\n"); */
                   2534:     }
1.243     brouard  2535:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2536:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2537:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2538:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2539:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2540:       /* decreased of more than 3.84  */
                   2541:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2542:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2543:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2544:                        
1.188     brouard  2545:       /* Starting the program with initial values given by a former maximization will simply change */
                   2546:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2547:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2548:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2549: #ifdef DEBUG
                   2550:       int k[2],l;
                   2551:       k[0]=1;
                   2552:       k[1]=-1;
                   2553:       printf("Max: %.12e",(*func)(p));
                   2554:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2555:       for (j=1;j<=n;j++) {
                   2556:        printf(" %.12e",p[j]);
                   2557:        fprintf(ficlog," %.12e",p[j]);
                   2558:       }
                   2559:       printf("\n");
                   2560:       fprintf(ficlog,"\n");
                   2561:       for(l=0;l<=1;l++) {
                   2562:        for (j=1;j<=n;j++) {
                   2563:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2564:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2565:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2566:        }
                   2567:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2568:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2569:       }
                   2570: #endif
                   2571: 
                   2572:       free_vector(xit,1,n); 
                   2573:       free_vector(xits,1,n); 
                   2574:       free_vector(ptt,1,n); 
                   2575:       free_vector(pt,1,n); 
                   2576:       return; 
1.192     brouard  2577:     } /* enough precision */ 
1.240     brouard  2578:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2579:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2580:       ptt[j]=2.0*p[j]-pt[j]; 
                   2581:       xit[j]=p[j]-pt[j]; 
                   2582:       pt[j]=p[j]; 
                   2583:     } 
1.181     brouard  2584:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2585: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2586:                if (*iter <=4) {
1.225     brouard  2587: #else
                   2588: #endif
1.224     brouard  2589: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2590: #else
1.161     brouard  2591:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2592: #endif
1.162     brouard  2593:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2594:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2595:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2596:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2597:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2598:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2599:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2600:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2601:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2602:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2603:       /* mu² and del² are equal when f3=f1 */
                   2604:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2605:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2606:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2607:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2608: #ifdef NRCORIGINAL
                   2609:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2610: #else
                   2611:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2612:       t= t- del*SQR(fp-fptt);
1.183     brouard  2613: #endif
1.202     brouard  2614:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2615: #ifdef DEBUG
1.181     brouard  2616:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2617:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2618:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2619:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2620:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2621:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2622:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2623:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2624: #endif
1.183     brouard  2625: #ifdef POWELLORIGINAL
                   2626:       if (t < 0.0) { /* Then we use it for new direction */
                   2627: #else
1.182     brouard  2628:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2629:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2630:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2631:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2632:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2633:       } 
1.181     brouard  2634:       if (directest < 0.0) { /* Then we use it for new direction */
                   2635: #endif
1.191     brouard  2636: #ifdef DEBUGLINMIN
1.234     brouard  2637:        printf("Before linmin in direction P%d-P0\n",n);
                   2638:        for (j=1;j<=n;j++) {
                   2639:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2640:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2641:          if(j % ncovmodel == 0){
                   2642:            printf("\n");
                   2643:            fprintf(ficlog,"\n");
                   2644:          }
                   2645:        }
1.224     brouard  2646: #endif
                   2647: #ifdef LINMINORIGINAL
1.234     brouard  2648:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2649: #else
1.234     brouard  2650:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2651:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2652: #endif
1.234     brouard  2653:        
1.191     brouard  2654: #ifdef DEBUGLINMIN
1.234     brouard  2655:        for (j=1;j<=n;j++) { 
                   2656:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2657:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2658:          if(j % ncovmodel == 0){
                   2659:            printf("\n");
                   2660:            fprintf(ficlog,"\n");
                   2661:          }
                   2662:        }
1.224     brouard  2663: #endif
1.234     brouard  2664:        for (j=1;j<=n;j++) { 
                   2665:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2666:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2667:        }
1.224     brouard  2668: #ifdef LINMINORIGINAL
                   2669: #else
1.234     brouard  2670:        for (j=1, flatd=0;j<=n;j++) {
                   2671:          if(flatdir[j]>0)
                   2672:            flatd++;
                   2673:        }
                   2674:        if(flatd >0){
1.255     brouard  2675:          printf("%d flat directions: ",flatd);
                   2676:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2677:          for (j=1;j<=n;j++) { 
                   2678:            if(flatdir[j]>0){
                   2679:              printf("%d ",j);
                   2680:              fprintf(ficlog,"%d ",j);
                   2681:            }
                   2682:          }
                   2683:          printf("\n");
                   2684:          fprintf(ficlog,"\n");
1.319     brouard  2685: #ifdef FLATSUP
                   2686:           free_vector(xit,1,n); 
                   2687:           free_vector(xits,1,n); 
                   2688:           free_vector(ptt,1,n); 
                   2689:           free_vector(pt,1,n); 
                   2690:           return;
                   2691: #endif
1.234     brouard  2692:        }
1.191     brouard  2693: #endif
1.234     brouard  2694:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2695:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2696:        
1.126     brouard  2697: #ifdef DEBUG
1.234     brouard  2698:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2699:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2700:        for(j=1;j<=n;j++){
                   2701:          printf(" %lf",xit[j]);
                   2702:          fprintf(ficlog," %lf",xit[j]);
                   2703:        }
                   2704:        printf("\n");
                   2705:        fprintf(ficlog,"\n");
1.126     brouard  2706: #endif
1.192     brouard  2707:       } /* end of t or directest negative */
1.224     brouard  2708: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2709: #else
1.234     brouard  2710:       } /* end if (fptt < fp)  */
1.192     brouard  2711: #endif
1.225     brouard  2712: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2713:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2714: #else
1.224     brouard  2715: #endif
1.234     brouard  2716:                } /* loop iteration */ 
1.126     brouard  2717: } 
1.234     brouard  2718:   
1.126     brouard  2719: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2720:   
1.235     brouard  2721:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2722:   {
1.279     brouard  2723:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2724:      *   (and selected quantitative values in nres)
                   2725:      *  by left multiplying the unit
                   2726:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2727:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2728:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2729:      * or prevalence in state 1, prevalence in state 2, 0
                   2730:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2731:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2732:      * Output is prlim.
                   2733:      * Initial matrix pimij 
                   2734:      */
1.206     brouard  2735:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2736:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2737:   /*  0,                   0                  , 1} */
                   2738:   /*
                   2739:    * and after some iteration: */
                   2740:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2741:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2742:   /*  0,                   0                  , 1} */
                   2743:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2744:   /* {0.51571254859325999, 0.4842874514067399, */
                   2745:   /*  0.51326036147820708, 0.48673963852179264} */
                   2746:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2747:     
1.126     brouard  2748:   int i, ii,j,k;
1.209     brouard  2749:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2750:   /* double **matprod2(); */ /* test */
1.218     brouard  2751:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2752:   double **newm;
1.209     brouard  2753:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2754:   int ncvloop=0;
1.288     brouard  2755:   int first=0;
1.169     brouard  2756:   
1.209     brouard  2757:   min=vector(1,nlstate);
                   2758:   max=vector(1,nlstate);
                   2759:   meandiff=vector(1,nlstate);
                   2760: 
1.218     brouard  2761:        /* Starting with matrix unity */
1.126     brouard  2762:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2763:     for (j=1;j<=nlstate+ndeath;j++){
                   2764:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2765:     }
1.169     brouard  2766:   
                   2767:   cov[1]=1.;
                   2768:   
                   2769:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2770:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2771:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2772:     ncvloop++;
1.126     brouard  2773:     newm=savm;
                   2774:     /* Covariates have to be included here again */
1.138     brouard  2775:     cov[2]=agefin;
1.319     brouard  2776:      if(nagesqr==1){
                   2777:       cov[3]= agefin*agefin;
                   2778:      }
1.234     brouard  2779:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2780:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2781:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.319     brouard  2782:       /* cov[++k1]=nbcode[TvarsD[k]][codtabm(ij,k)]; */
1.235     brouard  2783:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2784:     }
                   2785:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2786:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.319     brouard  2787:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k];
                   2788:       /* cov[++k1]=Tqresult[nres][k];  */
1.235     brouard  2789:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2790:     }
1.237     brouard  2791:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.319     brouard  2792:       if(Dummy[Tage[k]]==2){ /* dummy with age */
1.234     brouard  2793:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319     brouard  2794:        /* cov[++k1]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   2795:       } else if(Dummy[Tage[k]]==3){ /* quantitative with age */
                   2796:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k];
                   2797:        /* cov[++k1]=Tqresult[nres][k];  */
1.234     brouard  2798:       }
1.235     brouard  2799:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2800:     }
1.237     brouard  2801:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2802:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2803:       if(Dummy[Tvard[k][1]==0]){
                   2804:        if(Dummy[Tvard[k][2]==0]){
                   2805:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
1.319     brouard  2806:          /* cov[++k1]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.237     brouard  2807:        }else{
                   2808:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
1.319     brouard  2809:          /* cov[++k1]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k]; */
1.237     brouard  2810:        }
                   2811:       }else{
                   2812:        if(Dummy[Tvard[k][2]==0]){
                   2813:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
1.319     brouard  2814:          /* cov[++k1]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]]; */
1.237     brouard  2815:        }else{
                   2816:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
1.319     brouard  2817:          /* cov[++k1]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]]; */
1.237     brouard  2818:        }
                   2819:       }
1.234     brouard  2820:     }
1.138     brouard  2821:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2822:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2823:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2824:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2825:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.319     brouard  2826:     /* age and covariate values of ij are in 'cov' */
1.142     brouard  2827:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2828:     
1.126     brouard  2829:     savm=oldm;
                   2830:     oldm=newm;
1.209     brouard  2831: 
                   2832:     for(j=1; j<=nlstate; j++){
                   2833:       max[j]=0.;
                   2834:       min[j]=1.;
                   2835:     }
                   2836:     for(i=1;i<=nlstate;i++){
                   2837:       sumnew=0;
                   2838:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2839:       for(j=1; j<=nlstate; j++){ 
                   2840:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2841:        max[j]=FMAX(max[j],prlim[i][j]);
                   2842:        min[j]=FMIN(min[j],prlim[i][j]);
                   2843:       }
                   2844:     }
                   2845: 
1.126     brouard  2846:     maxmax=0.;
1.209     brouard  2847:     for(j=1; j<=nlstate; j++){
                   2848:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2849:       maxmax=FMAX(maxmax,meandiff[j]);
                   2850:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2851:     } /* j loop */
1.203     brouard  2852:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2853:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2854:     if(maxmax < ftolpl){
1.209     brouard  2855:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2856:       free_vector(min,1,nlstate);
                   2857:       free_vector(max,1,nlstate);
                   2858:       free_vector(meandiff,1,nlstate);
1.126     brouard  2859:       return prlim;
                   2860:     }
1.288     brouard  2861:   } /* agefin loop */
1.208     brouard  2862:     /* After some age loop it doesn't converge */
1.288     brouard  2863:   if(!first){
                   2864:     first=1;
                   2865:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
1.317     brouard  2866:     fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2867:   }else if (first >=1 && first <10){
                   2868:     fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2869:     first++;
                   2870:   }else if (first ==10){
                   2871:     fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2872:     printf("Warning: the stable prevalence dit not converge. This warning came too often, IMaCh will stop notifying, even in its log file. Look at the graphs to appreciate the non convergence.\n");
                   2873:     fprintf(ficlog,"Warning: the stable prevalence no convergence; too many cases, giving up noticing, even in log file\n");
                   2874:     first++;
1.288     brouard  2875:   }
                   2876: 
1.209     brouard  2877:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2878:   free_vector(min,1,nlstate);
                   2879:   free_vector(max,1,nlstate);
                   2880:   free_vector(meandiff,1,nlstate);
1.208     brouard  2881:   
1.169     brouard  2882:   return prlim; /* should not reach here */
1.126     brouard  2883: }
                   2884: 
1.217     brouard  2885: 
                   2886:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2887: 
1.218     brouard  2888:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2889:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2890:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2891: {
1.264     brouard  2892:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2893:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2894:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2895:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2896:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2897:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2898:   /* Initial matrix pimij */
                   2899:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2900:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2901:   /*  0,                   0                  , 1} */
                   2902:   /*
                   2903:    * and after some iteration: */
                   2904:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2905:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2906:   /*  0,                   0                  , 1} */
                   2907:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2908:   /* {0.51571254859325999, 0.4842874514067399, */
                   2909:   /*  0.51326036147820708, 0.48673963852179264} */
                   2910:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2911: 
                   2912:   int i, ii,j,k;
1.247     brouard  2913:   int first=0;
1.217     brouard  2914:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2915:   /* double **matprod2(); */ /* test */
                   2916:   double **out, cov[NCOVMAX+1], **bmij();
                   2917:   double **newm;
1.218     brouard  2918:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2919:   double        **oldm, **savm;  /* for use */
                   2920: 
1.217     brouard  2921:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2922:   int ncvloop=0;
                   2923:   
                   2924:   min=vector(1,nlstate);
                   2925:   max=vector(1,nlstate);
                   2926:   meandiff=vector(1,nlstate);
                   2927: 
1.266     brouard  2928:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2929:   oldm=oldms; savm=savms;
                   2930:   
                   2931:   /* Starting with matrix unity */
                   2932:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2933:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2934:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2935:     }
                   2936:   
                   2937:   cov[1]=1.;
                   2938:   
                   2939:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2940:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2941:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2942:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2943:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2944:     ncvloop++;
1.218     brouard  2945:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2946:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2947:     /* Covariates have to be included here again */
                   2948:     cov[2]=agefin;
1.319     brouard  2949:     if(nagesqr==1){
1.217     brouard  2950:       cov[3]= agefin*agefin;;
1.319     brouard  2951:     }
1.242     brouard  2952:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2953:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2954:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2955:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2956:     }
                   2957:     /* for (k=1; k<=cptcovn;k++) { */
                   2958:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2959:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2960:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2961:     /* } */
                   2962:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2963:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2964:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2965:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2966:     }
                   2967:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2968:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2969:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2970:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2971:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.319     brouard  2972:       /* if(Dummy[Tvar[Tage[k]]]== 2){ /\* dummy with age *\/ ERROR ???*/
                   2973:       if(Dummy[Tage[k]]== 2){ /* dummy with age */
1.242     brouard  2974:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319     brouard  2975:       } else if(Dummy[Tage[k]]== 3){ /* quantitative with age */
                   2976:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k];
1.242     brouard  2977:       }
                   2978:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2979:     }
                   2980:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2981:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2982:       if(Dummy[Tvard[k][1]==0]){
                   2983:        if(Dummy[Tvard[k][2]==0]){
                   2984:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2985:        }else{
                   2986:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2987:        }
                   2988:       }else{
                   2989:        if(Dummy[Tvard[k][2]==0]){
                   2990:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2991:        }else{
                   2992:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2993:        }
                   2994:       }
1.217     brouard  2995:     }
                   2996:     
                   2997:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2998:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2999:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   3000:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3001:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  3002:                /* ij should be linked to the correct index of cov */
                   3003:                /* age and covariate values ij are in 'cov', but we need to pass
                   3004:                 * ij for the observed prevalence at age and status and covariate
                   3005:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   3006:                 */
                   3007:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   3008:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   3009:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  3010:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  3011:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   3012:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   3013:     /*         printf("%d newm= ",i); */
                   3014:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3015:     /*           printf("%f ",newm[i][j]); */
                   3016:     /*         } */
                   3017:     /*         printf("oldm * "); */
                   3018:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3019:     /*           printf("%f ",oldm[i][j]); */
                   3020:     /*         } */
1.268     brouard  3021:     /*         printf(" bmmij "); */
1.266     brouard  3022:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3023:     /*           printf("%f ",pmmij[i][j]); */
                   3024:     /*         } */
                   3025:     /*         printf("\n"); */
                   3026:     /*   } */
                   3027:     /* } */
1.217     brouard  3028:     savm=oldm;
                   3029:     oldm=newm;
1.266     brouard  3030: 
1.217     brouard  3031:     for(j=1; j<=nlstate; j++){
                   3032:       max[j]=0.;
                   3033:       min[j]=1.;
                   3034:     }
                   3035:     for(j=1; j<=nlstate; j++){ 
                   3036:       for(i=1;i<=nlstate;i++){
1.234     brouard  3037:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   3038:        bprlim[i][j]= newm[i][j];
                   3039:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   3040:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  3041:       }
                   3042:     }
1.218     brouard  3043:                
1.217     brouard  3044:     maxmax=0.;
                   3045:     for(i=1; i<=nlstate; i++){
1.318     brouard  3046:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column, could be nan! */
1.217     brouard  3047:       maxmax=FMAX(maxmax,meandiff[i]);
                   3048:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  3049:     } /* i loop */
1.217     brouard  3050:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  3051:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  3052:     if(maxmax < ftolpl){
1.220     brouard  3053:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  3054:       free_vector(min,1,nlstate);
                   3055:       free_vector(max,1,nlstate);
                   3056:       free_vector(meandiff,1,nlstate);
                   3057:       return bprlim;
                   3058:     }
1.288     brouard  3059:   } /* agefin loop */
1.217     brouard  3060:     /* After some age loop it doesn't converge */
1.288     brouard  3061:   if(!first){
1.247     brouard  3062:     first=1;
                   3063:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   3064: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   3065:   }
                   3066:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  3067: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   3068:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   3069:   free_vector(min,1,nlstate);
                   3070:   free_vector(max,1,nlstate);
                   3071:   free_vector(meandiff,1,nlstate);
                   3072:   
                   3073:   return bprlim; /* should not reach here */
                   3074: }
                   3075: 
1.126     brouard  3076: /*************** transition probabilities ***************/ 
                   3077: 
                   3078: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   3079: {
1.138     brouard  3080:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  3081:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  3082:      model to the ncovmodel covariates (including constant and age).
                   3083:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3084:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3085:      ncth covariate in the global vector x is given by the formula:
                   3086:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3087:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3088:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3089:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  3090:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  3091:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  3092:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  3093:   */
                   3094:   double s1, lnpijopii;
1.126     brouard  3095:   /*double t34;*/
1.164     brouard  3096:   int i,j, nc, ii, jj;
1.126     brouard  3097: 
1.223     brouard  3098:   for(i=1; i<= nlstate; i++){
                   3099:     for(j=1; j<i;j++){
                   3100:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3101:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3102:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3103:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3104:       }
                   3105:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3106:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3107:     }
                   3108:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3109:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3110:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3111:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3112:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3113:       }
                   3114:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3115:     }
                   3116:   }
1.218     brouard  3117:   
1.223     brouard  3118:   for(i=1; i<= nlstate; i++){
                   3119:     s1=0;
                   3120:     for(j=1; j<i; j++){
                   3121:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3122:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3123:     }
                   3124:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3125:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3126:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3127:     }
                   3128:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3129:     ps[i][i]=1./(s1+1.);
                   3130:     /* Computing other pijs */
                   3131:     for(j=1; j<i; j++)
                   3132:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3133:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3134:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3135:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3136:   } /* end i */
1.218     brouard  3137:   
1.223     brouard  3138:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3139:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3140:       ps[ii][jj]=0;
                   3141:       ps[ii][ii]=1;
                   3142:     }
                   3143:   }
1.294     brouard  3144: 
                   3145: 
1.223     brouard  3146:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3147:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3148:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3149:   /*   } */
                   3150:   /*   printf("\n "); */
                   3151:   /* } */
                   3152:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3153:   /*
                   3154:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  3155:                goto end;*/
1.266     brouard  3156:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  3157: }
                   3158: 
1.218     brouard  3159: /*************** backward transition probabilities ***************/ 
                   3160: 
                   3161:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3162: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3163:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   3164: {
1.302     brouard  3165:   /* Computes the backward probability at age agefin, cov[2], and covariate combination 'ij'. In fact cov is already filled and x too.
1.266     brouard  3166:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  3167:    */
1.218     brouard  3168:   int i, ii, j,k;
1.222     brouard  3169:   
                   3170:   double **out, **pmij();
                   3171:   double sumnew=0.;
1.218     brouard  3172:   double agefin;
1.292     brouard  3173:   double k3=0.; /* constant of the w_x diagonal matrix (in order for B to sum to 1 even for death state) */
1.222     brouard  3174:   double **dnewm, **dsavm, **doldm;
                   3175:   double **bbmij;
                   3176:   
1.218     brouard  3177:   doldm=ddoldms; /* global pointers */
1.222     brouard  3178:   dnewm=ddnewms;
                   3179:   dsavm=ddsavms;
1.318     brouard  3180: 
                   3181:   /* Debug */
                   3182:   /* printf("Bmij ij=%d, cov[2}=%f\n", ij, cov[2]); */
1.222     brouard  3183:   agefin=cov[2];
1.268     brouard  3184:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3185:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3186:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3187:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3188: 
                   3189:   /* P_x */
1.266     brouard  3190:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  3191:   /* outputs pmmij which is a stochastic matrix in row */
                   3192: 
                   3193:   /* Diag(w_x) */
1.292     brouard  3194:   /* Rescaling the cross-sectional prevalence: Problem with prevacurrent which can be zero */
1.268     brouard  3195:   sumnew=0.;
1.269     brouard  3196:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3197:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.297     brouard  3198:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]); */
1.268     brouard  3199:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3200:   }
                   3201:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3202:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3203:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3204:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3205:     }
                   3206:   }else{
                   3207:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3208:       for (j=1;j<=nlstate+ndeath;j++)
                   3209:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3210:     }
                   3211:     /* if(sumnew <0.9){ */
                   3212:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3213:     /* } */
                   3214:   }
                   3215:   k3=0.0;  /* We put the last diagonal to 0 */
                   3216:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3217:       doldm[ii][ii]= k3;
                   3218:   }
                   3219:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3220:   
1.292     brouard  3221:   /* Left product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm): diag[(w_i)*Px */
                   3222:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* was a Bug Valgrind */
1.268     brouard  3223: 
1.292     brouard  3224:   /* Diag(Sum_i w^i_x p^ij_x, should be the prevalence at age x+stepm */
1.268     brouard  3225:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3226:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3227:     sumnew=0.;
1.222     brouard  3228:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3229:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3230:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3231:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3232:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3233:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3234:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3235:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3236:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3237:        /* }else */
1.268     brouard  3238:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3239:     } /*End ii */
                   3240:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3241: 
1.292     brouard  3242:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* was a Bug Valgrind */
1.268     brouard  3243:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3244:   /* end bmij */
1.266     brouard  3245:   return ps; /*pointer is unchanged */
1.218     brouard  3246: }
1.217     brouard  3247: /*************** transition probabilities ***************/ 
                   3248: 
1.218     brouard  3249: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3250: {
                   3251:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3252:      computes the probability to be observed in state j being in state i by appying the
                   3253:      model to the ncovmodel covariates (including constant and age).
                   3254:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3255:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3256:      ncth covariate in the global vector x is given by the formula:
                   3257:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3258:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3259:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3260:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3261:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3262:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3263:   */
                   3264:   double s1, lnpijopii;
                   3265:   /*double t34;*/
                   3266:   int i,j, nc, ii, jj;
                   3267: 
1.234     brouard  3268:   for(i=1; i<= nlstate; i++){
                   3269:     for(j=1; j<i;j++){
                   3270:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3271:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3272:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3273:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3274:       }
                   3275:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3276:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3277:     }
                   3278:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3279:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3280:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3281:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3282:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3283:       }
                   3284:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3285:     }
                   3286:   }
                   3287:   
                   3288:   for(i=1; i<= nlstate; i++){
                   3289:     s1=0;
                   3290:     for(j=1; j<i; j++){
                   3291:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3292:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3293:     }
                   3294:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3295:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3296:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3297:     }
                   3298:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3299:     ps[i][i]=1./(s1+1.);
                   3300:     /* Computing other pijs */
                   3301:     for(j=1; j<i; j++)
                   3302:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3303:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3304:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3305:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3306:   } /* end i */
                   3307:   
                   3308:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3309:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3310:       ps[ii][jj]=0;
                   3311:       ps[ii][ii]=1;
                   3312:     }
                   3313:   }
1.296     brouard  3314:   /* Added for prevbcast */ /* Transposed matrix too */
1.234     brouard  3315:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3316:     s1=0.;
                   3317:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3318:       s1+=ps[ii][jj];
                   3319:     }
                   3320:     for(ii=1; ii<= nlstate; ii++){
                   3321:       ps[ii][jj]=ps[ii][jj]/s1;
                   3322:     }
                   3323:   }
                   3324:   /* Transposition */
                   3325:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3326:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3327:       s1=ps[ii][jj];
                   3328:       ps[ii][jj]=ps[jj][ii];
                   3329:       ps[jj][ii]=s1;
                   3330:     }
                   3331:   }
                   3332:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3333:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3334:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3335:   /*   } */
                   3336:   /*   printf("\n "); */
                   3337:   /* } */
                   3338:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3339:   /*
                   3340:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3341:     goto end;*/
                   3342:   return ps;
1.217     brouard  3343: }
                   3344: 
                   3345: 
1.126     brouard  3346: /**************** Product of 2 matrices ******************/
                   3347: 
1.145     brouard  3348: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3349: {
                   3350:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3351:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3352:   /* in, b, out are matrice of pointers which should have been initialized 
                   3353:      before: only the contents of out is modified. The function returns
                   3354:      a pointer to pointers identical to out */
1.145     brouard  3355:   int i, j, k;
1.126     brouard  3356:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3357:     for(k=ncolol; k<=ncoloh; k++){
                   3358:       out[i][k]=0.;
                   3359:       for(j=ncl; j<=nch; j++)
                   3360:        out[i][k] +=in[i][j]*b[j][k];
                   3361:     }
1.126     brouard  3362:   return out;
                   3363: }
                   3364: 
                   3365: 
                   3366: /************* Higher Matrix Product ***************/
                   3367: 
1.235     brouard  3368: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3369: {
1.218     brouard  3370:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3371:      'nhstepm*hstepm*stepm' months (i.e. until
                   3372:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3373:      nhstepm*hstepm matrices. 
                   3374:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3375:      (typically every 2 years instead of every month which is too big 
                   3376:      for the memory).
                   3377:      Model is determined by parameters x and covariates have to be 
                   3378:      included manually here. 
                   3379: 
                   3380:      */
                   3381: 
                   3382:   int i, j, d, h, k;
1.131     brouard  3383:   double **out, cov[NCOVMAX+1];
1.126     brouard  3384:   double **newm;
1.187     brouard  3385:   double agexact;
1.214     brouard  3386:   double agebegin, ageend;
1.126     brouard  3387: 
                   3388:   /* Hstepm could be zero and should return the unit matrix */
                   3389:   for (i=1;i<=nlstate+ndeath;i++)
                   3390:     for (j=1;j<=nlstate+ndeath;j++){
                   3391:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3392:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3393:     }
                   3394:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3395:   for(h=1; h <=nhstepm; h++){
                   3396:     for(d=1; d <=hstepm; d++){
                   3397:       newm=savm;
                   3398:       /* Covariates have to be included here again */
                   3399:       cov[1]=1.;
1.214     brouard  3400:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3401:       cov[2]=agexact;
1.319     brouard  3402:       if(nagesqr==1){
1.227     brouard  3403:        cov[3]= agexact*agexact;
1.319     brouard  3404:       }
1.235     brouard  3405:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
1.319     brouard  3406: /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3407:        /* codtabm(ij,k)  (1 & (ij-1) >> (k-1))+1 */
                   3408: /*             V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   3409: /*    k        1  2   3   4     5    6    7     8    9 */
                   3410: /*Tvar[k]=     5  4   3   6     5    2    7     1    1 */
                   3411: /*    nsd         1   2                              3 */ /* Counting single dummies covar fixed or tv */
                   3412: /*TvarsD[nsd]     4   3                              1 */ /* ID of single dummy cova fixed or timevary*/
                   3413: /*TvarsDind[k]    2   3                              9 */ /* position K of single dummy cova */
1.235     brouard  3414:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3415:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3416:       }
                   3417:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3418:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.319     brouard  3419:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k];
1.235     brouard  3420:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3421:       }
1.319     brouard  3422:       for (k=1; k<=cptcovage;k++){ /* For product with age V1+V1*age +V4 +age*V3 */
                   3423:        /* 1+2 Tage[1]=2 TVar[2]=1 Dummy[2]=2, Tage[2]=4 TVar[4]=3 Dummy[4]=3 quant*/
                   3424:        /* */
                   3425:        if(Dummy[Tage[k]]== 2){ /* dummy with age */
                   3426:        /* if(Dummy[Tvar[Tage[k]]]== 2){ /\* dummy with age *\/ */
1.235     brouard  3427:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319     brouard  3428:        } else if(Dummy[Tage[k]]== 3){ /* quantitative with age */
                   3429:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k];
1.235     brouard  3430:        }
                   3431:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3432:       }
1.319     brouard  3433:       for (k=1; k<=cptcovprod;k++){ /*  For product without age */
1.235     brouard  3434:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.319     brouard  3435:        /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   3436:        if(Dummy[Tvard[k][1]==0]){
                   3437:          if(Dummy[Tvard[k][2]==0]){
                   3438:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3439:          }else{
                   3440:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   3441:          }
                   3442:        }else{
                   3443:          if(Dummy[Tvard[k][2]==0]){
                   3444:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   3445:          }else{
                   3446:            cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   3447:          }
                   3448:        }
1.235     brouard  3449:       }
                   3450:       /* for (k=1; k<=cptcovn;k++)  */
                   3451:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3452:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3453:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3454:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3455:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3456:       
                   3457:       
1.126     brouard  3458:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3459:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.319     brouard  3460:       /* right multiplication of oldm by the current matrix */
1.126     brouard  3461:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3462:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3463:       /* if((int)age == 70){ */
                   3464:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3465:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3466:       /*         printf("%d pmmij ",i); */
                   3467:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3468:       /*           printf("%f ",pmmij[i][j]); */
                   3469:       /*         } */
                   3470:       /*         printf(" oldm "); */
                   3471:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3472:       /*           printf("%f ",oldm[i][j]); */
                   3473:       /*         } */
                   3474:       /*         printf("\n"); */
                   3475:       /*       } */
                   3476:       /* } */
1.126     brouard  3477:       savm=oldm;
                   3478:       oldm=newm;
                   3479:     }
                   3480:     for(i=1; i<=nlstate+ndeath; i++)
                   3481:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3482:        po[i][j][h]=newm[i][j];
                   3483:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3484:       }
1.128     brouard  3485:     /*printf("h=%d ",h);*/
1.126     brouard  3486:   } /* end h */
1.267     brouard  3487:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3488:   return po;
                   3489: }
                   3490: 
1.217     brouard  3491: /************* Higher Back Matrix Product ***************/
1.218     brouard  3492: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3493: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3494: {
1.266     brouard  3495:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3496:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3497:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3498:      nhstepm*hstepm matrices.
                   3499:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3500:      (typically every 2 years instead of every month which is too big
1.217     brouard  3501:      for the memory).
1.218     brouard  3502:      Model is determined by parameters x and covariates have to be
1.266     brouard  3503:      included manually here. Then we use a call to bmij(x and cov)
                   3504:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3505:   */
1.217     brouard  3506: 
                   3507:   int i, j, d, h, k;
1.266     brouard  3508:   double **out, cov[NCOVMAX+1], **bmij();
                   3509:   double **newm, ***newmm;
1.217     brouard  3510:   double agexact;
                   3511:   double agebegin, ageend;
1.222     brouard  3512:   double **oldm, **savm;
1.217     brouard  3513: 
1.266     brouard  3514:   newmm=po; /* To be saved */
                   3515:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3516:   /* Hstepm could be zero and should return the unit matrix */
                   3517:   for (i=1;i<=nlstate+ndeath;i++)
                   3518:     for (j=1;j<=nlstate+ndeath;j++){
                   3519:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3520:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3521:     }
                   3522:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3523:   for(h=1; h <=nhstepm; h++){
                   3524:     for(d=1; d <=hstepm; d++){
                   3525:       newm=savm;
                   3526:       /* Covariates have to be included here again */
                   3527:       cov[1]=1.;
1.271     brouard  3528:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3529:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
1.318     brouard  3530:         /* Debug */
                   3531:       /* printf("hBxij age=%lf, agexact=%lf\n", age, agexact); */
1.217     brouard  3532:       cov[2]=agexact;
                   3533:       if(nagesqr==1)
1.222     brouard  3534:        cov[3]= agexact*agexact;
1.266     brouard  3535:       for (k=1; k<=cptcovn;k++){
                   3536:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3537:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3538:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3539:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3540:       }
1.267     brouard  3541:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3542:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3543:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3544:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3545:       }
1.319     brouard  3546:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 *//* For product with age */
                   3547:        /* if(Dummy[Tvar[Tage[k]]]== 2){ /\* dummy with age error!!!*\/ */
                   3548:        if(Dummy[Tage[k]]== 2){ /* dummy with age */
1.267     brouard  3549:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319     brouard  3550:        } else if(Dummy[Tage[k]]== 3){ /* quantitative with age */
1.267     brouard  3551:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3552:        }
                   3553:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3554:       }
                   3555:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3556:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3557:       }                        
1.217     brouard  3558:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3559:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3560: 
1.218     brouard  3561:       /* Careful transposed matrix */
1.266     brouard  3562:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3563:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3564:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3565:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3566:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3567:       /* if((int)age == 70){ */
                   3568:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3569:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3570:       /*         printf("%d pmmij ",i); */
                   3571:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3572:       /*           printf("%f ",pmmij[i][j]); */
                   3573:       /*         } */
                   3574:       /*         printf(" oldm "); */
                   3575:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3576:       /*           printf("%f ",oldm[i][j]); */
                   3577:       /*         } */
                   3578:       /*         printf("\n"); */
                   3579:       /*       } */
                   3580:       /* } */
                   3581:       savm=oldm;
                   3582:       oldm=newm;
                   3583:     }
                   3584:     for(i=1; i<=nlstate+ndeath; i++)
                   3585:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3586:        po[i][j][h]=newm[i][j];
1.268     brouard  3587:        /* if(h==nhstepm) */
                   3588:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3589:       }
1.268     brouard  3590:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3591:   } /* end h */
1.268     brouard  3592:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3593:   return po;
                   3594: }
                   3595: 
                   3596: 
1.162     brouard  3597: #ifdef NLOPT
                   3598:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3599:   double fret;
                   3600:   double *xt;
                   3601:   int j;
                   3602:   myfunc_data *d2 = (myfunc_data *) pd;
                   3603: /* xt = (p1-1); */
                   3604:   xt=vector(1,n); 
                   3605:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3606: 
                   3607:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3608:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3609:   printf("Function = %.12lf ",fret);
                   3610:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3611:   printf("\n");
                   3612:  free_vector(xt,1,n);
                   3613:   return fret;
                   3614: }
                   3615: #endif
1.126     brouard  3616: 
                   3617: /*************** log-likelihood *************/
                   3618: double func( double *x)
                   3619: {
1.226     brouard  3620:   int i, ii, j, k, mi, d, kk;
                   3621:   int ioffset=0;
                   3622:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3623:   double **out;
                   3624:   double lli; /* Individual log likelihood */
                   3625:   int s1, s2;
1.228     brouard  3626:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3627:   double bbh, survp;
                   3628:   long ipmx;
                   3629:   double agexact;
                   3630:   /*extern weight */
                   3631:   /* We are differentiating ll according to initial status */
                   3632:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3633:   /*for(i=1;i<imx;i++) 
                   3634:     printf(" %d\n",s[4][i]);
                   3635:   */
1.162     brouard  3636: 
1.226     brouard  3637:   ++countcallfunc;
1.162     brouard  3638: 
1.226     brouard  3639:   cov[1]=1.;
1.126     brouard  3640: 
1.226     brouard  3641:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3642:   ioffset=0;
1.226     brouard  3643:   if(mle==1){
                   3644:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3645:       /* Computes the values of the ncovmodel covariates of the model
                   3646:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3647:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3648:         to be observed in j being in i according to the model.
                   3649:       */
1.243     brouard  3650:       ioffset=2+nagesqr ;
1.233     brouard  3651:    /* Fixed */
1.319     brouard  3652:       for (k=1; k<=ncovf;k++){ /* For each fixed covariate dummu or quant or prod */
                   3653:        /* # V1=sex, V2=raedyrs Quant Fixed, State=livarnb4..livarnb11, V3=iadl4..iald11, V4=adlw4..adlw11, V5=r4bmi..r11bmi */
                   3654:         /*             V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   3655:        /*  TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  ID of fixed covariates or product V2, V1*V2, V1 */
1.320     brouard  3656:         /* TvarFind;  TvarFind[1]=6,  TvarFind[2]=7, TvarFind[3]=9 *//* Inverse V2(6) is first fixed (single or prod)  */
1.319     brouard  3657:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (TvarFind[1]=6)*/
                   3658:        /* V1*V2 (7)  TvarFind[2]=7, TvarFind[3]=9 */
1.234     brouard  3659:       }
1.226     brouard  3660:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
1.319     brouard  3661:         is 5, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2]=6 
1.226     brouard  3662:         has been calculated etc */
                   3663:       /* For an individual i, wav[i] gives the number of effective waves */
                   3664:       /* We compute the contribution to Likelihood of each effective transition
                   3665:         mw[mi][i] is real wave of the mi th effectve wave */
                   3666:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3667:         s2=s[mw[mi+1][i]][i];
                   3668:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3669:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3670:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3671:       */
                   3672:       for(mi=1; mi<= wav[i]-1; mi++){
1.319     brouard  3673:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates in the model (single and product but no age )"V5+V4+V3+V4*V3+V5*age+V1*age+V1" +TvarVind 1,2,3,4(V4*V3)  Tvar[1]@7{5, 4, 3, 6, 5, 1, 1 ; 6 because the created covar is after V5 and is 6, minus 1+1, 3,2,1,4 positions in cotvar*/
                   3674:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; but where is the crossproduct? */
1.242     brouard  3675:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3676:        }
                   3677:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3678:          for (j=1;j<=nlstate+ndeath;j++){
                   3679:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3680:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3681:          }
                   3682:        for(d=0; d<dh[mi][i]; d++){
                   3683:          newm=savm;
                   3684:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3685:          cov[2]=agexact;
                   3686:          if(nagesqr==1)
                   3687:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3688:          for (kk=1; kk<=cptcovage;kk++) {
1.318     brouard  3689:            if(!FixedV[Tvar[Tage[kk]]])
                   3690:              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
                   3691:            else
                   3692:              cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3693:          }
                   3694:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3695:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3696:          savm=oldm;
                   3697:          oldm=newm;
                   3698:        } /* end mult */
                   3699:        
                   3700:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3701:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3702:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3703:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3704:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3705:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3706:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3707:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3708:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3709:                                 * -stepm/2 to stepm/2 .
                   3710:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3711:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3712:                                 */
1.234     brouard  3713:        s1=s[mw[mi][i]][i];
                   3714:        s2=s[mw[mi+1][i]][i];
                   3715:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3716:        /* bias bh is positive if real duration
                   3717:         * is higher than the multiple of stepm and negative otherwise.
                   3718:         */
                   3719:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3720:        if( s2 > nlstate){ 
                   3721:          /* i.e. if s2 is a death state and if the date of death is known 
                   3722:             then the contribution to the likelihood is the probability to 
                   3723:             die between last step unit time and current  step unit time, 
                   3724:             which is also equal to probability to die before dh 
                   3725:             minus probability to die before dh-stepm . 
                   3726:             In version up to 0.92 likelihood was computed
                   3727:             as if date of death was unknown. Death was treated as any other
                   3728:             health state: the date of the interview describes the actual state
                   3729:             and not the date of a change in health state. The former idea was
                   3730:             to consider that at each interview the state was recorded
                   3731:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3732:             introduced the exact date of death then we should have modified
                   3733:             the contribution of an exact death to the likelihood. This new
                   3734:             contribution is smaller and very dependent of the step unit
                   3735:             stepm. It is no more the probability to die between last interview
                   3736:             and month of death but the probability to survive from last
                   3737:             interview up to one month before death multiplied by the
                   3738:             probability to die within a month. Thanks to Chris
                   3739:             Jackson for correcting this bug.  Former versions increased
                   3740:             mortality artificially. The bad side is that we add another loop
                   3741:             which slows down the processing. The difference can be up to 10%
                   3742:             lower mortality.
                   3743:          */
                   3744:          /* If, at the beginning of the maximization mostly, the
                   3745:             cumulative probability or probability to be dead is
                   3746:             constant (ie = 1) over time d, the difference is equal to
                   3747:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3748:             s1 at precedent wave, to be dead a month before current
                   3749:             wave is equal to probability, being at state s1 at
                   3750:             precedent wave, to be dead at mont of the current
                   3751:             wave. Then the observed probability (that this person died)
                   3752:             is null according to current estimated parameter. In fact,
                   3753:             it should be very low but not zero otherwise the log go to
                   3754:             infinity.
                   3755:          */
1.183     brouard  3756: /* #ifdef INFINITYORIGINAL */
                   3757: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3758: /* #else */
                   3759: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3760: /*         lli=log(mytinydouble); */
                   3761: /*       else */
                   3762: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3763: /* #endif */
1.226     brouard  3764:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3765:          
1.226     brouard  3766:        } else if  ( s2==-1 ) { /* alive */
                   3767:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3768:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3769:          /*survp += out[s1][j]; */
                   3770:          lli= log(survp);
                   3771:        }
                   3772:        else if  (s2==-4) { 
                   3773:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3774:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3775:          lli= log(survp); 
                   3776:        } 
                   3777:        else if  (s2==-5) { 
                   3778:          for (j=1,survp=0. ; j<=2; j++)  
                   3779:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3780:          lli= log(survp); 
                   3781:        } 
                   3782:        else{
                   3783:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3784:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3785:        } 
                   3786:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3787:        /*if(lli ==000.0)*/
                   3788:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3789:        ipmx +=1;
                   3790:        sw += weight[i];
                   3791:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3792:        /* if (lli < log(mytinydouble)){ */
                   3793:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3794:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3795:        /* } */
                   3796:       } /* end of wave */
                   3797:     } /* end of individual */
                   3798:   }  else if(mle==2){
                   3799:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.319     brouard  3800:       ioffset=2+nagesqr ;
                   3801:       for (k=1; k<=ncovf;k++)
                   3802:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];
1.226     brouard  3803:       for(mi=1; mi<= wav[i]-1; mi++){
1.319     brouard  3804:        for(k=1; k <= ncovv ; k++){
                   3805:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3806:        }
1.226     brouard  3807:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3808:          for (j=1;j<=nlstate+ndeath;j++){
                   3809:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3810:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3811:          }
                   3812:        for(d=0; d<=dh[mi][i]; d++){
                   3813:          newm=savm;
                   3814:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3815:          cov[2]=agexact;
                   3816:          if(nagesqr==1)
                   3817:            cov[3]= agexact*agexact;
                   3818:          for (kk=1; kk<=cptcovage;kk++) {
                   3819:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3820:          }
                   3821:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3822:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3823:          savm=oldm;
                   3824:          oldm=newm;
                   3825:        } /* end mult */
                   3826:       
                   3827:        s1=s[mw[mi][i]][i];
                   3828:        s2=s[mw[mi+1][i]][i];
                   3829:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3830:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3831:        ipmx +=1;
                   3832:        sw += weight[i];
                   3833:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3834:       } /* end of wave */
                   3835:     } /* end of individual */
                   3836:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3837:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3838:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3839:       for(mi=1; mi<= wav[i]-1; mi++){
                   3840:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3841:          for (j=1;j<=nlstate+ndeath;j++){
                   3842:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3843:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3844:          }
                   3845:        for(d=0; d<dh[mi][i]; d++){
                   3846:          newm=savm;
                   3847:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3848:          cov[2]=agexact;
                   3849:          if(nagesqr==1)
                   3850:            cov[3]= agexact*agexact;
                   3851:          for (kk=1; kk<=cptcovage;kk++) {
                   3852:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3853:          }
                   3854:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3855:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3856:          savm=oldm;
                   3857:          oldm=newm;
                   3858:        } /* end mult */
                   3859:       
                   3860:        s1=s[mw[mi][i]][i];
                   3861:        s2=s[mw[mi+1][i]][i];
                   3862:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3863:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3864:        ipmx +=1;
                   3865:        sw += weight[i];
                   3866:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3867:       } /* end of wave */
                   3868:     } /* end of individual */
                   3869:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3870:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3871:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3872:       for(mi=1; mi<= wav[i]-1; mi++){
                   3873:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3874:          for (j=1;j<=nlstate+ndeath;j++){
                   3875:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3876:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3877:          }
                   3878:        for(d=0; d<dh[mi][i]; d++){
                   3879:          newm=savm;
                   3880:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3881:          cov[2]=agexact;
                   3882:          if(nagesqr==1)
                   3883:            cov[3]= agexact*agexact;
                   3884:          for (kk=1; kk<=cptcovage;kk++) {
                   3885:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3886:          }
1.126     brouard  3887:        
1.226     brouard  3888:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3889:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3890:          savm=oldm;
                   3891:          oldm=newm;
                   3892:        } /* end mult */
                   3893:       
                   3894:        s1=s[mw[mi][i]][i];
                   3895:        s2=s[mw[mi+1][i]][i];
                   3896:        if( s2 > nlstate){ 
                   3897:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3898:        } else if  ( s2==-1 ) { /* alive */
                   3899:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3900:            survp += out[s1][j];
                   3901:          lli= log(survp);
                   3902:        }else{
                   3903:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3904:        }
                   3905:        ipmx +=1;
                   3906:        sw += weight[i];
                   3907:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3908: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3909:       } /* end of wave */
                   3910:     } /* end of individual */
                   3911:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3912:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3913:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3914:       for(mi=1; mi<= wav[i]-1; mi++){
                   3915:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3916:          for (j=1;j<=nlstate+ndeath;j++){
                   3917:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3918:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3919:          }
                   3920:        for(d=0; d<dh[mi][i]; d++){
                   3921:          newm=savm;
                   3922:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3923:          cov[2]=agexact;
                   3924:          if(nagesqr==1)
                   3925:            cov[3]= agexact*agexact;
                   3926:          for (kk=1; kk<=cptcovage;kk++) {
                   3927:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3928:          }
1.126     brouard  3929:        
1.226     brouard  3930:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3931:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3932:          savm=oldm;
                   3933:          oldm=newm;
                   3934:        } /* end mult */
                   3935:       
                   3936:        s1=s[mw[mi][i]][i];
                   3937:        s2=s[mw[mi+1][i]][i];
                   3938:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3939:        ipmx +=1;
                   3940:        sw += weight[i];
                   3941:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3942:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3943:       } /* end of wave */
                   3944:     } /* end of individual */
                   3945:   } /* End of if */
                   3946:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3947:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3948:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3949:   return -l;
1.126     brouard  3950: }
                   3951: 
                   3952: /*************** log-likelihood *************/
                   3953: double funcone( double *x)
                   3954: {
1.228     brouard  3955:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3956:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3957:   int ioffset=0;
1.131     brouard  3958:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3959:   double **out;
                   3960:   double lli; /* Individual log likelihood */
                   3961:   double llt;
                   3962:   int s1, s2;
1.228     brouard  3963:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3964: 
1.126     brouard  3965:   double bbh, survp;
1.187     brouard  3966:   double agexact;
1.214     brouard  3967:   double agebegin, ageend;
1.126     brouard  3968:   /*extern weight */
                   3969:   /* We are differentiating ll according to initial status */
                   3970:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3971:   /*for(i=1;i<imx;i++) 
                   3972:     printf(" %d\n",s[4][i]);
                   3973:   */
                   3974:   cov[1]=1.;
                   3975: 
                   3976:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3977:   ioffset=0;
                   3978:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3979:     /* ioffset=2+nagesqr+cptcovage; */
                   3980:     ioffset=2+nagesqr;
1.232     brouard  3981:     /* Fixed */
1.224     brouard  3982:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3983:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
1.311     brouard  3984:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products *//* Missing values are set to -1 but should be dropped */
1.232     brouard  3985:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3986: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3987: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3988: /*    cov[2+6]=covar[2][i]; V2  */
                   3989: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3990: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3991: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3992: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3993: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3994: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3995:     }
1.232     brouard  3996:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3997:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3998:     /* } */
1.231     brouard  3999:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   4000:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   4001:     /* } */
1.225     brouard  4002:     
1.233     brouard  4003: 
                   4004:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  4005:     /* Wave varying (but not age varying) */
                   4006:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  4007:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   4008:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   4009:       }
1.232     brouard  4010:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  4011:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   4012:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   4013:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   4014:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   4015:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  4016:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  4017:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   4018:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   4019:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  4020:       /* } */
1.126     brouard  4021:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  4022:        for (j=1;j<=nlstate+ndeath;j++){
                   4023:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   4024:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   4025:        }
1.214     brouard  4026:       
                   4027:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   4028:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   4029:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  4030:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  4031:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4032:          and mw[mi+1][i]. dh depends on stepm.*/
                   4033:        newm=savm;
1.247     brouard  4034:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  4035:        cov[2]=agexact;
                   4036:        if(nagesqr==1)
                   4037:          cov[3]= agexact*agexact;
                   4038:        for (kk=1; kk<=cptcovage;kk++) {
                   4039:          if(!FixedV[Tvar[Tage[kk]]])
                   4040:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   4041:          else
                   4042:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   4043:        }
                   4044:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   4045:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   4046:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   4047:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   4048:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   4049:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   4050:        savm=oldm;
                   4051:        oldm=newm;
1.126     brouard  4052:       } /* end mult */
                   4053:       
                   4054:       s1=s[mw[mi][i]][i];
                   4055:       s2=s[mw[mi+1][i]][i];
1.217     brouard  4056:       /* if(s2==-1){ */
1.268     brouard  4057:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  4058:       /*       /\* exit(1); *\/ */
                   4059:       /* } */
1.126     brouard  4060:       bbh=(double)bh[mi][i]/(double)stepm; 
                   4061:       /* bias is positive if real duration
                   4062:        * is higher than the multiple of stepm and negative otherwise.
                   4063:        */
                   4064:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  4065:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  4066:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  4067:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   4068:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   4069:        lli= log(survp);
1.126     brouard  4070:       }else if (mle==1){
1.242     brouard  4071:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  4072:       } else if(mle==2){
1.242     brouard  4073:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  4074:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  4075:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  4076:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  4077:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  4078:       } else{  /* mle=0 back to 1 */
1.242     brouard  4079:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   4080:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  4081:       } /* End of if */
                   4082:       ipmx +=1;
                   4083:       sw += weight[i];
                   4084:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  4085:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  4086:       if(globpr){
1.246     brouard  4087:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  4088:  %11.6f %11.6f %11.6f ", \
1.242     brouard  4089:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  4090:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  4091:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   4092:          llt +=ll[k]*gipmx/gsw;
                   4093:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   4094:        }
                   4095:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  4096:       }
1.232     brouard  4097:        } /* end of wave */
                   4098: } /* end of individual */
                   4099: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   4100: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   4101: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   4102: if(globpr==0){ /* First time we count the contributions and weights */
                   4103:        gipmx=ipmx;
                   4104:        gsw=sw;
                   4105: }
                   4106: return -l;
1.126     brouard  4107: }
                   4108: 
                   4109: 
                   4110: /*************** function likelione ***********/
1.292     brouard  4111: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*func)(double []))
1.126     brouard  4112: {
                   4113:   /* This routine should help understanding what is done with 
                   4114:      the selection of individuals/waves and
                   4115:      to check the exact contribution to the likelihood.
                   4116:      Plotting could be done.
                   4117:    */
                   4118:   int k;
                   4119: 
                   4120:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  4121:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  4122:     strcat(fileresilk,fileresu);
1.126     brouard  4123:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   4124:       printf("Problem with resultfile: %s\n", fileresilk);
                   4125:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   4126:     }
1.214     brouard  4127:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   4128:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  4129:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   4130:     for(k=1; k<=nlstate; k++) 
                   4131:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   4132:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   4133:   }
                   4134: 
1.292     brouard  4135:   *fretone=(*func)(p);
1.126     brouard  4136:   if(*globpri !=0){
                   4137:     fclose(ficresilk);
1.205     brouard  4138:     if (mle ==0)
                   4139:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   4140:     else if(mle >=1)
                   4141:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   4142:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  4143:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  4144:       
                   4145:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  4146:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  4147: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   4148:     }
1.207     brouard  4149:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  4150: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4151:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  4152: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4153:     fflush(fichtm);
1.205     brouard  4154:   }
1.126     brouard  4155:   return;
                   4156: }
                   4157: 
                   4158: 
                   4159: /*********** Maximum Likelihood Estimation ***************/
                   4160: 
                   4161: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   4162: {
1.319     brouard  4163:   int i,j,k, jk, jkk=0, iter=0;
1.126     brouard  4164:   double **xi;
                   4165:   double fret;
                   4166:   double fretone; /* Only one call to likelihood */
                   4167:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  4168: 
                   4169: #ifdef NLOPT
                   4170:   int creturn;
                   4171:   nlopt_opt opt;
                   4172:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   4173:   double *lb;
                   4174:   double minf; /* the minimum objective value, upon return */
                   4175:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   4176:   myfunc_data dinst, *d = &dinst;
                   4177: #endif
                   4178: 
                   4179: 
1.126     brouard  4180:   xi=matrix(1,npar,1,npar);
                   4181:   for (i=1;i<=npar;i++)
                   4182:     for (j=1;j<=npar;j++)
                   4183:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   4184:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  4185:   strcpy(filerespow,"POW_"); 
1.126     brouard  4186:   strcat(filerespow,fileres);
                   4187:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   4188:     printf("Problem with resultfile: %s\n", filerespow);
                   4189:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   4190:   }
                   4191:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   4192:   for (i=1;i<=nlstate;i++)
                   4193:     for(j=1;j<=nlstate+ndeath;j++)
                   4194:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   4195:   fprintf(ficrespow,"\n");
1.162     brouard  4196: #ifdef POWELL
1.319     brouard  4197: #ifdef LINMINORIGINAL
                   4198: #else /* LINMINORIGINAL */
                   4199:   
                   4200:   flatdir=ivector(1,npar); 
                   4201:   for (j=1;j<=npar;j++) flatdir[j]=0; 
                   4202: #endif /*LINMINORIGINAL */
                   4203: 
                   4204: #ifdef FLATSUP
                   4205:   powell(p,xi,npar,ftol,&iter,&fret,flatdir,func);
                   4206:   /* reorganizing p by suppressing flat directions */
                   4207:   for(i=1, jk=1; i <=nlstate; i++){
                   4208:     for(k=1; k <=(nlstate+ndeath); k++){
                   4209:       if (k != i) {
                   4210:         printf("%d%d flatdir[%d]=%d",i,k,jk, flatdir[jk]);
                   4211:         if(flatdir[jk]==1){
                   4212:           printf(" To be skipped %d%d flatdir[%d]=%d ",i,k,jk, flatdir[jk]);
                   4213:         }
                   4214:         for(j=1; j <=ncovmodel; j++){
                   4215:           printf("%12.7f ",p[jk]);
                   4216:           jk++; 
                   4217:         }
                   4218:         printf("\n");
                   4219:       }
                   4220:     }
                   4221:   }
                   4222: /* skipping */
                   4223:   /* for(i=1, jk=1, jkk=1;(flatdir[jk]==0)&& (i <=nlstate); i++){ */
                   4224:   for(i=1, jk=1, jkk=1;i <=nlstate; i++){
                   4225:     for(k=1; k <=(nlstate+ndeath); k++){
                   4226:       if (k != i) {
                   4227:         printf("%d%d flatdir[%d]=%d",i,k,jk, flatdir[jk]);
                   4228:         if(flatdir[jk]==1){
                   4229:           printf(" To be skipped %d%d flatdir[%d]=%d jk=%d p[%d] ",i,k,jk, flatdir[jk],jk, jk);
                   4230:           for(j=1; j <=ncovmodel;  jk++,j++){
                   4231:             printf(" p[%d]=%12.7f",jk, p[jk]);
                   4232:             /*q[jjk]=p[jk];*/
                   4233:           }
                   4234:         }else{
                   4235:           printf(" To be kept %d%d flatdir[%d]=%d jk=%d q[%d]=p[%d] ",i,k,jk, flatdir[jk],jk, jkk, jk);
                   4236:           for(j=1; j <=ncovmodel;  jk++,jkk++,j++){
                   4237:             printf(" p[%d]=%12.7f=q[%d]",jk, p[jk],jkk);
                   4238:             /*q[jjk]=p[jk];*/
                   4239:           }
                   4240:         }
                   4241:         printf("\n");
                   4242:       }
                   4243:       fflush(stdout);
                   4244:     }
                   4245:   }
                   4246:   powell(p,xi,npar,ftol,&iter,&fret,flatdir,func);
                   4247: #else  /* FLATSUP */
1.126     brouard  4248:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.319     brouard  4249: #endif  /* FLATSUP */
                   4250: 
                   4251: #ifdef LINMINORIGINAL
                   4252: #else
                   4253:       free_ivector(flatdir,1,npar); 
                   4254: #endif  /* LINMINORIGINAL*/
                   4255: #endif /* POWELL */
1.126     brouard  4256: 
1.162     brouard  4257: #ifdef NLOPT
                   4258: #ifdef NEWUOA
                   4259:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   4260: #else
                   4261:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   4262: #endif
                   4263:   lb=vector(0,npar-1);
                   4264:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   4265:   nlopt_set_lower_bounds(opt, lb);
                   4266:   nlopt_set_initial_step1(opt, 0.1);
                   4267:   
                   4268:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   4269:   d->function = func;
                   4270:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   4271:   nlopt_set_min_objective(opt, myfunc, d);
                   4272:   nlopt_set_xtol_rel(opt, ftol);
                   4273:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   4274:     printf("nlopt failed! %d\n",creturn); 
                   4275:   }
                   4276:   else {
                   4277:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4278:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4279:     iter=1; /* not equal */
                   4280:   }
                   4281:   nlopt_destroy(opt);
                   4282: #endif
1.319     brouard  4283: #ifdef FLATSUP
                   4284:   /* npared = npar -flatd/ncovmodel; */
                   4285:   /* xired= matrix(1,npared,1,npared); */
                   4286:   /* paramred= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */
                   4287:   /* powell(pred,xired,npared,ftol,&iter,&fret,flatdir,func); */
                   4288:   /* free_matrix(xire,1,npared,1,npared); */
                   4289: #else  /* FLATSUP */
                   4290: #endif /* FLATSUP */
1.126     brouard  4291:   free_matrix(xi,1,npar,1,npar);
                   4292:   fclose(ficrespow);
1.203     brouard  4293:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4294:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4295:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4296: 
                   4297: }
                   4298: 
                   4299: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4300: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4301: {
                   4302:   double  **a,**y,*x,pd;
1.203     brouard  4303:   /* double **hess; */
1.164     brouard  4304:   int i, j;
1.126     brouard  4305:   int *indx;
                   4306: 
                   4307:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4308:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4309:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4310:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4311:   double gompertz(double p[]);
1.203     brouard  4312:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4313: 
                   4314:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4315:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4316:   for (i=1;i<=npar;i++){
1.203     brouard  4317:     printf("%d-",i);fflush(stdout);
                   4318:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4319:    
                   4320:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4321:     
                   4322:     /*  printf(" %f ",p[i]);
                   4323:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4324:   }
                   4325:   
                   4326:   for (i=1;i<=npar;i++) {
                   4327:     for (j=1;j<=npar;j++)  {
                   4328:       if (j>i) { 
1.203     brouard  4329:        printf(".%d-%d",i,j);fflush(stdout);
                   4330:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4331:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4332:        
                   4333:        hess[j][i]=hess[i][j];    
                   4334:        /*printf(" %lf ",hess[i][j]);*/
                   4335:       }
                   4336:     }
                   4337:   }
                   4338:   printf("\n");
                   4339:   fprintf(ficlog,"\n");
                   4340: 
                   4341:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4342:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4343:   
                   4344:   a=matrix(1,npar,1,npar);
                   4345:   y=matrix(1,npar,1,npar);
                   4346:   x=vector(1,npar);
                   4347:   indx=ivector(1,npar);
                   4348:   for (i=1;i<=npar;i++)
                   4349:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4350:   ludcmp(a,npar,indx,&pd);
                   4351: 
                   4352:   for (j=1;j<=npar;j++) {
                   4353:     for (i=1;i<=npar;i++) x[i]=0;
                   4354:     x[j]=1;
                   4355:     lubksb(a,npar,indx,x);
                   4356:     for (i=1;i<=npar;i++){ 
                   4357:       matcov[i][j]=x[i];
                   4358:     }
                   4359:   }
                   4360: 
                   4361:   printf("\n#Hessian matrix#\n");
                   4362:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4363:   for (i=1;i<=npar;i++) { 
                   4364:     for (j=1;j<=npar;j++) { 
1.203     brouard  4365:       printf("%.6e ",hess[i][j]);
                   4366:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4367:     }
                   4368:     printf("\n");
                   4369:     fprintf(ficlog,"\n");
                   4370:   }
                   4371: 
1.203     brouard  4372:   /* printf("\n#Covariance matrix#\n"); */
                   4373:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4374:   /* for (i=1;i<=npar;i++) {  */
                   4375:   /*   for (j=1;j<=npar;j++) {  */
                   4376:   /*     printf("%.6e ",matcov[i][j]); */
                   4377:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4378:   /*   } */
                   4379:   /*   printf("\n"); */
                   4380:   /*   fprintf(ficlog,"\n"); */
                   4381:   /* } */
                   4382: 
1.126     brouard  4383:   /* Recompute Inverse */
1.203     brouard  4384:   /* for (i=1;i<=npar;i++) */
                   4385:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4386:   /* ludcmp(a,npar,indx,&pd); */
                   4387: 
                   4388:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4389: 
                   4390:   /* for (j=1;j<=npar;j++) { */
                   4391:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4392:   /*   x[j]=1; */
                   4393:   /*   lubksb(a,npar,indx,x); */
                   4394:   /*   for (i=1;i<=npar;i++){  */
                   4395:   /*     y[i][j]=x[i]; */
                   4396:   /*     printf("%.3e ",y[i][j]); */
                   4397:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4398:   /*   } */
                   4399:   /*   printf("\n"); */
                   4400:   /*   fprintf(ficlog,"\n"); */
                   4401:   /* } */
                   4402: 
                   4403:   /* Verifying the inverse matrix */
                   4404: #ifdef DEBUGHESS
                   4405:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4406: 
1.203     brouard  4407:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4408:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4409: 
                   4410:   for (j=1;j<=npar;j++) {
                   4411:     for (i=1;i<=npar;i++){ 
1.203     brouard  4412:       printf("%.2f ",y[i][j]);
                   4413:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4414:     }
                   4415:     printf("\n");
                   4416:     fprintf(ficlog,"\n");
                   4417:   }
1.203     brouard  4418: #endif
1.126     brouard  4419: 
                   4420:   free_matrix(a,1,npar,1,npar);
                   4421:   free_matrix(y,1,npar,1,npar);
                   4422:   free_vector(x,1,npar);
                   4423:   free_ivector(indx,1,npar);
1.203     brouard  4424:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4425: 
                   4426: 
                   4427: }
                   4428: 
                   4429: /*************** hessian matrix ****************/
                   4430: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4431: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4432:   int i;
                   4433:   int l=1, lmax=20;
1.203     brouard  4434:   double k1,k2, res, fx;
1.132     brouard  4435:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4436:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4437:   int k=0,kmax=10;
                   4438:   double l1;
                   4439: 
                   4440:   fx=func(x);
                   4441:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4442:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4443:     l1=pow(10,l);
                   4444:     delts=delt;
                   4445:     for(k=1 ; k <kmax; k=k+1){
                   4446:       delt = delta*(l1*k);
                   4447:       p2[theta]=x[theta] +delt;
1.145     brouard  4448:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4449:       p2[theta]=x[theta]-delt;
                   4450:       k2=func(p2)-fx;
                   4451:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4452:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4453:       
1.203     brouard  4454: #ifdef DEBUGHESSII
1.126     brouard  4455:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4456:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4457: #endif
                   4458:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4459:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4460:        k=kmax;
                   4461:       }
                   4462:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4463:        k=kmax; l=lmax*10;
1.126     brouard  4464:       }
                   4465:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4466:        delts=delt;
                   4467:       }
1.203     brouard  4468:     } /* End loop k */
1.126     brouard  4469:   }
                   4470:   delti[theta]=delts;
                   4471:   return res; 
                   4472:   
                   4473: }
                   4474: 
1.203     brouard  4475: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4476: {
                   4477:   int i;
1.164     brouard  4478:   int l=1, lmax=20;
1.126     brouard  4479:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4480:   double p2[MAXPARM+1];
1.203     brouard  4481:   int k, kmax=1;
                   4482:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4483: 
                   4484:   int firstime=0;
1.203     brouard  4485:   
1.126     brouard  4486:   fx=func(x);
1.203     brouard  4487:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4488:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4489:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4490:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4491:     k1=func(p2)-fx;
                   4492:   
1.203     brouard  4493:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4494:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4495:     k2=func(p2)-fx;
                   4496:   
1.203     brouard  4497:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4498:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4499:     k3=func(p2)-fx;
                   4500:   
1.203     brouard  4501:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4502:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4503:     k4=func(p2)-fx;
1.203     brouard  4504:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4505:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4506:       firstime=1;
1.203     brouard  4507:       kmax=kmax+10;
1.208     brouard  4508:     }
                   4509:     if(kmax >=10 || firstime ==1){
1.246     brouard  4510:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4511:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4512:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4513:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4514:     }
                   4515: #ifdef DEBUGHESSIJ
                   4516:     v1=hess[thetai][thetai];
                   4517:     v2=hess[thetaj][thetaj];
                   4518:     cv12=res;
                   4519:     /* Computing eigen value of Hessian matrix */
                   4520:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4521:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4522:     if ((lc2 <0) || (lc1 <0) ){
                   4523:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4524:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4525:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4526:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4527:     }
1.126     brouard  4528: #endif
                   4529:   }
                   4530:   return res;
                   4531: }
                   4532: 
1.203     brouard  4533:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4534: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4535: /* { */
                   4536: /*   int i; */
                   4537: /*   int l=1, lmax=20; */
                   4538: /*   double k1,k2,k3,k4,res,fx; */
                   4539: /*   double p2[MAXPARM+1]; */
                   4540: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4541: /*   int k=0,kmax=10; */
                   4542: /*   double l1; */
                   4543:   
                   4544: /*   fx=func(x); */
                   4545: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4546: /*     l1=pow(10,l); */
                   4547: /*     delts=delt; */
                   4548: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4549: /*       delt = delti*(l1*k); */
                   4550: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4551: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4552: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4553: /*       k1=func(p2)-fx; */
                   4554:       
                   4555: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4556: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4557: /*       k2=func(p2)-fx; */
                   4558:       
                   4559: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4560: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4561: /*       k3=func(p2)-fx; */
                   4562:       
                   4563: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4564: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4565: /*       k4=func(p2)-fx; */
                   4566: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4567: /* #ifdef DEBUGHESSIJ */
                   4568: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4569: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4570: /* #endif */
                   4571: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4572: /*     k=kmax; */
                   4573: /*       } */
                   4574: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4575: /*     k=kmax; l=lmax*10; */
                   4576: /*       } */
                   4577: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4578: /*     delts=delt; */
                   4579: /*       } */
                   4580: /*     } /\* End loop k *\/ */
                   4581: /*   } */
                   4582: /*   delti[theta]=delts; */
                   4583: /*   return res;  */
                   4584: /* } */
                   4585: 
                   4586: 
1.126     brouard  4587: /************** Inverse of matrix **************/
                   4588: void ludcmp(double **a, int n, int *indx, double *d) 
                   4589: { 
                   4590:   int i,imax,j,k; 
                   4591:   double big,dum,sum,temp; 
                   4592:   double *vv; 
                   4593:  
                   4594:   vv=vector(1,n); 
                   4595:   *d=1.0; 
                   4596:   for (i=1;i<=n;i++) { 
                   4597:     big=0.0; 
                   4598:     for (j=1;j<=n;j++) 
                   4599:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4600:     if (big == 0.0){
                   4601:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4602:       for (j=1;j<=n;j++) {
                   4603:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4604:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4605:       }
                   4606:       fflush(ficlog);
                   4607:       fclose(ficlog);
                   4608:       nrerror("Singular matrix in routine ludcmp"); 
                   4609:     }
1.126     brouard  4610:     vv[i]=1.0/big; 
                   4611:   } 
                   4612:   for (j=1;j<=n;j++) { 
                   4613:     for (i=1;i<j;i++) { 
                   4614:       sum=a[i][j]; 
                   4615:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4616:       a[i][j]=sum; 
                   4617:     } 
                   4618:     big=0.0; 
                   4619:     for (i=j;i<=n;i++) { 
                   4620:       sum=a[i][j]; 
                   4621:       for (k=1;k<j;k++) 
                   4622:        sum -= a[i][k]*a[k][j]; 
                   4623:       a[i][j]=sum; 
                   4624:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4625:        big=dum; 
                   4626:        imax=i; 
                   4627:       } 
                   4628:     } 
                   4629:     if (j != imax) { 
                   4630:       for (k=1;k<=n;k++) { 
                   4631:        dum=a[imax][k]; 
                   4632:        a[imax][k]=a[j][k]; 
                   4633:        a[j][k]=dum; 
                   4634:       } 
                   4635:       *d = -(*d); 
                   4636:       vv[imax]=vv[j]; 
                   4637:     } 
                   4638:     indx[j]=imax; 
                   4639:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4640:     if (j != n) { 
                   4641:       dum=1.0/(a[j][j]); 
                   4642:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4643:     } 
                   4644:   } 
                   4645:   free_vector(vv,1,n);  /* Doesn't work */
                   4646: ;
                   4647: } 
                   4648: 
                   4649: void lubksb(double **a, int n, int *indx, double b[]) 
                   4650: { 
                   4651:   int i,ii=0,ip,j; 
                   4652:   double sum; 
                   4653:  
                   4654:   for (i=1;i<=n;i++) { 
                   4655:     ip=indx[i]; 
                   4656:     sum=b[ip]; 
                   4657:     b[ip]=b[i]; 
                   4658:     if (ii) 
                   4659:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4660:     else if (sum) ii=i; 
                   4661:     b[i]=sum; 
                   4662:   } 
                   4663:   for (i=n;i>=1;i--) { 
                   4664:     sum=b[i]; 
                   4665:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4666:     b[i]=sum/a[i][i]; 
                   4667:   } 
                   4668: } 
                   4669: 
                   4670: void pstamp(FILE *fichier)
                   4671: {
1.196     brouard  4672:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4673: }
                   4674: 
1.297     brouard  4675: void date2dmy(double date,double *day, double *month, double *year){
                   4676:   double yp=0., yp1=0., yp2=0.;
                   4677:   
                   4678:   yp1=modf(date,&yp);/* extracts integral of date in yp  and
                   4679:                        fractional in yp1 */
                   4680:   *year=yp;
                   4681:   yp2=modf((yp1*12),&yp);
                   4682:   *month=yp;
                   4683:   yp1=modf((yp2*30.5),&yp);
                   4684:   *day=yp;
                   4685:   if(*day==0) *day=1;
                   4686:   if(*month==0) *month=1;
                   4687: }
                   4688: 
1.253     brouard  4689: 
                   4690: 
1.126     brouard  4691: /************ Frequencies ********************/
1.251     brouard  4692: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4693:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4694:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4695: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4696:   
1.265     brouard  4697:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4698:   int iind=0, iage=0;
                   4699:   int mi; /* Effective wave */
                   4700:   int first;
                   4701:   double ***freq; /* Frequencies */
1.268     brouard  4702:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4703:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4704:   double *meanq, *stdq, *idq;
1.226     brouard  4705:   double **meanqt;
                   4706:   double *pp, **prop, *posprop, *pospropt;
                   4707:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4708:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4709:   double agebegin, ageend;
                   4710:     
                   4711:   pp=vector(1,nlstate);
1.251     brouard  4712:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4713:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4714:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4715:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4716:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4717:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4718:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4719:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4720:   strcpy(fileresp,"P_");
                   4721:   strcat(fileresp,fileresu);
                   4722:   /*strcat(fileresphtm,fileresu);*/
                   4723:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4724:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4725:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4726:     exit(0);
                   4727:   }
1.240     brouard  4728:   
1.226     brouard  4729:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4730:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4731:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4732:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4733:     fflush(ficlog);
                   4734:     exit(70); 
                   4735:   }
                   4736:   else{
                   4737:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4738: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4739: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4740:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4741:   }
1.319     brouard  4742:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies (weight=%d) and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm, weightopt);
1.240     brouard  4743:   
1.226     brouard  4744:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4745:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4746:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4747:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4748:     fflush(ficlog);
                   4749:     exit(70); 
1.240     brouard  4750:   } else{
1.226     brouard  4751:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.319     brouard  4752: ,<hr size=\"2\" color=\"#EC5E5E\"> \n                                  \
1.214     brouard  4753: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4754:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4755:   }
1.319     brouard  4756:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>(weight=%d) frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr,weightopt);
1.240     brouard  4757:   
1.253     brouard  4758:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4759:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4760:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4761:   j1=0;
1.126     brouard  4762:   
1.227     brouard  4763:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4764:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4765:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4766:   
                   4767:   
1.226     brouard  4768:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4769:      reference=low_education V1=0,V2=0
                   4770:      med_educ                V1=1 V2=0, 
                   4771:      high_educ               V1=0 V2=1
                   4772:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4773:   */
1.249     brouard  4774:   dateintsum=0;
                   4775:   k2cpt=0;
                   4776: 
1.253     brouard  4777:   if(cptcoveff == 0 )
1.265     brouard  4778:     nl=1;  /* Constant and age model only */
1.253     brouard  4779:   else
                   4780:     nl=2;
1.265     brouard  4781: 
                   4782:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4783:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4784:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4785:    *     freq[s1][s2][iage] =0.
                   4786:    *     Loop on iind
                   4787:    *       ++freq[s1][s2][iage] weighted
                   4788:    *     end iind
                   4789:    *     if covariate and j!0
                   4790:    *       headers Variable on one line
                   4791:    *     endif cov j!=0
                   4792:    *     header of frequency table by age
                   4793:    *     Loop on age
                   4794:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4795:    *       pos+=freq[s1][s2][iage] weighted
                   4796:    *       Loop on s1 initial state
                   4797:    *         fprintf(ficresp
                   4798:    *       end s1
                   4799:    *     end age
                   4800:    *     if j!=0 computes starting values
                   4801:    *     end compute starting values
                   4802:    *   end j1
                   4803:    * end nl 
                   4804:    */
1.253     brouard  4805:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4806:     if(nj==1)
                   4807:       j=0;  /* First pass for the constant */
1.265     brouard  4808:     else{
1.253     brouard  4809:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4810:     }
1.251     brouard  4811:     first=1;
1.265     brouard  4812:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4813:       posproptt=0.;
                   4814:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4815:        scanf("%d", i);*/
                   4816:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4817:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4818:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4819:            freq[i][s2][m]=0;
1.251     brouard  4820:       
                   4821:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4822:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4823:          prop[i][m]=0;
                   4824:        posprop[i]=0;
                   4825:        pospropt[i]=0;
                   4826:       }
1.283     brouard  4827:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4828:         idq[z1]=0.;
                   4829:         meanq[z1]=0.;
                   4830:         stdq[z1]=0.;
1.283     brouard  4831:       }
                   4832:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4833:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4834:       /*         meanqt[m][z1]=0.; */
                   4835:       /*       } */
                   4836:       /* }       */
1.251     brouard  4837:       /* dateintsum=0; */
                   4838:       /* k2cpt=0; */
                   4839:       
1.265     brouard  4840:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4841:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4842:        bool=1;
                   4843:        if(j !=0){
                   4844:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4845:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4846:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4847:                /* if(Tvaraff[z1] ==-20){ */
                   4848:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4849:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4850:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4851:                /* }else  */
                   4852:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4853:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4854:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4855:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4856:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4857:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4858:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4859:                } /* Onlyf fixed */
                   4860:              } /* end z1 */
                   4861:            } /* cptcovn > 0 */
                   4862:          } /* end any */
                   4863:        }/* end j==0 */
1.265     brouard  4864:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4865:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4866:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4867:            m=mw[mi][iind];
                   4868:            if(j!=0){
                   4869:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4870:                for (z1=1; z1<=cptcoveff; z1++) {
                   4871:                  if( Fixed[Tmodelind[z1]]==1){
                   4872:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4873:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4874:                                                                                      value is -1, we don't select. It differs from the 
                   4875:                                                                                      constant and age model which counts them. */
                   4876:                      bool=0; /* not selected */
                   4877:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4878:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4879:                      bool=0;
                   4880:                    }
                   4881:                  }
                   4882:                }
                   4883:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4884:            } /* end j==0 */
                   4885:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4886:            if(bool==1){ /*Selected */
1.251     brouard  4887:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4888:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4889:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4890:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4891:              if(m >=firstpass && m <=lastpass){
                   4892:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4893:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4894:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4895:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4896:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4897:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4898:                if (m<lastpass) {
                   4899:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4900:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4901:                  if(s[m][iind]==-1)
                   4902:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4903:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.311     brouard  4904:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean on known values only */
                   4905:                    if(!isnan(covar[ncovcol+z1][iind])){
                   4906:                        idq[z1]=idq[z1]+weight[iind];
                   4907:                        meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4908:                        /* stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; *//*error*/
                   4909:                        stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4910:                    }
1.284     brouard  4911:                  }
1.251     brouard  4912:                  /* if((int)agev[m][iind] == 55) */
                   4913:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4914:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4915:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4916:                }
1.251     brouard  4917:              } /* end if between passes */  
                   4918:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4919:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4920:                k2cpt++;
                   4921:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4922:              }
1.251     brouard  4923:            }else{
                   4924:              bool=1;
                   4925:            }/* end bool 2 */
                   4926:          } /* end m */
1.284     brouard  4927:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4928:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4929:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4930:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4931:          /* } */
1.251     brouard  4932:        } /* end bool */
                   4933:       } /* end iind = 1 to imx */
1.319     brouard  4934:       /* prop[s][age] is fed for any initial and valid live state as well as
1.251     brouard  4935:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4936:       
                   4937:       
                   4938:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4939:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4940:         pstamp(ficresp);
1.251     brouard  4941:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4942:         pstamp(ficresp);
1.251     brouard  4943:        printf( "\n#********** Variable "); 
                   4944:        fprintf(ficresp, "\n#********** Variable "); 
                   4945:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4946:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4947:        fprintf(ficlog, "\n#********** Variable "); 
                   4948:        for (z1=1; z1<=cptcoveff; z1++){
                   4949:          if(!FixedV[Tvaraff[z1]]){
                   4950:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4951:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4952:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4953:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4954:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4955:          }else{
1.251     brouard  4956:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4957:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4958:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4959:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4960:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4961:          }
                   4962:        }
                   4963:        printf( "**********\n#");
                   4964:        fprintf(ficresp, "**********\n#");
                   4965:        fprintf(ficresphtm, "**********</h3>\n");
                   4966:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4967:        fprintf(ficlog, "**********\n");
                   4968:       }
1.284     brouard  4969:       /*
                   4970:        Printing means of quantitative variables if any
                   4971:       */
                   4972:       for (z1=1; z1<= nqfveff; z1++) {
1.311     brouard  4973:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.3g (weighted) individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.312     brouard  4974:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
1.284     brouard  4975:        if(weightopt==1){
                   4976:          printf(" Weighted mean and standard deviation of");
                   4977:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4978:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4979:        }
1.311     brouard  4980:        /* mu = \frac{w x}{\sum w}
                   4981:            var = \frac{\sum w (x-mu)^2}{\sum w} = \frac{w x^2}{\sum w} - mu^2 
                   4982:        */
                   4983:        printf(" fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   4984:        fprintf(ficlog," fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   4985:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.3g (weighted) representatives of the population : %8.5g (%8.5g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
1.284     brouard  4986:       }
                   4987:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4988:       /*       for(m=1;m<=lastpass;m++){ */
                   4989:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4990:       /*   } */
                   4991:       /* } */
1.283     brouard  4992: 
1.251     brouard  4993:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4994:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4995:         fprintf(ficresp, " Age");
                   4996:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4997:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4998:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4999:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   5000:       }
1.265     brouard  5001:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  5002:       fprintf(ficresphtm, "\n");
                   5003:       
                   5004:       /* Header of frequency table by age */
                   5005:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   5006:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  5007:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  5008:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  5009:          if(s2!=0 && m!=0)
                   5010:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  5011:        }
1.226     brouard  5012:       }
1.251     brouard  5013:       fprintf(ficresphtmfr, "\n");
                   5014:     
                   5015:       /* For each age */
                   5016:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   5017:        fprintf(ficresphtm,"<tr>");
                   5018:        if(iage==iagemax+1){
                   5019:          fprintf(ficlog,"1");
                   5020:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   5021:        }else if(iage==iagemax+2){
                   5022:          fprintf(ficlog,"0");
                   5023:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   5024:        }else if(iage==iagemax+3){
                   5025:          fprintf(ficlog,"Total");
                   5026:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   5027:        }else{
1.240     brouard  5028:          if(first==1){
1.251     brouard  5029:            first=0;
                   5030:            printf("See log file for details...\n");
                   5031:          }
                   5032:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   5033:          fprintf(ficlog,"Age %d", iage);
                   5034:        }
1.265     brouard  5035:        for(s1=1; s1 <=nlstate ; s1++){
                   5036:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   5037:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  5038:        }
1.265     brouard  5039:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  5040:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  5041:            pos += freq[s1][m][iage];
                   5042:          if(pp[s1]>=1.e-10){
1.251     brouard  5043:            if(first==1){
1.265     brouard  5044:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  5045:            }
1.265     brouard  5046:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  5047:          }else{
                   5048:            if(first==1)
1.265     brouard  5049:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   5050:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  5051:          }
                   5052:        }
                   5053:       
1.265     brouard  5054:        for(s1=1; s1 <=nlstate ; s1++){ 
                   5055:          /* posprop[s1]=0; */
                   5056:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   5057:            pp[s1] += freq[s1][m][iage];
                   5058:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   5059:       
                   5060:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   5061:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   5062:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   5063:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   5064:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   5065:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   5066:        }
                   5067:        
                   5068:        /* Writing ficresp */
                   5069:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   5070:           if( iage <= iagemax){
                   5071:            fprintf(ficresp," %d",iage);
                   5072:           }
                   5073:         }else if( nj==2){
                   5074:           if( iage <= iagemax){
                   5075:            fprintf(ficresp," %d",iage);
                   5076:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   5077:           }
1.240     brouard  5078:        }
1.265     brouard  5079:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  5080:          if(pos>=1.e-5){
1.251     brouard  5081:            if(first==1)
1.265     brouard  5082:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   5083:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  5084:          }else{
                   5085:            if(first==1)
1.265     brouard  5086:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   5087:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  5088:          }
                   5089:          if( iage <= iagemax){
                   5090:            if(pos>=1.e-5){
1.265     brouard  5091:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   5092:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   5093:               }else if( nj==2){
                   5094:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   5095:               }
                   5096:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   5097:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   5098:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   5099:            } else{
                   5100:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   5101:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  5102:            }
1.240     brouard  5103:          }
1.265     brouard  5104:          pospropt[s1] +=posprop[s1];
                   5105:        } /* end loop s1 */
1.251     brouard  5106:        /* pospropt=0.; */
1.265     brouard  5107:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  5108:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  5109:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  5110:              if(first==1){
1.265     brouard  5111:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  5112:              }
1.265     brouard  5113:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   5114:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  5115:            }
1.265     brouard  5116:            if(s1!=0 && m!=0)
                   5117:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  5118:          }
1.265     brouard  5119:        } /* end loop s1 */
1.251     brouard  5120:        posproptt=0.; 
1.265     brouard  5121:        for(s1=1; s1 <=nlstate; s1++){
                   5122:          posproptt += pospropt[s1];
1.251     brouard  5123:        }
                   5124:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  5125:        fprintf(ficresphtm,"</tr>\n");
                   5126:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   5127:          if(iage <= iagemax)
                   5128:            fprintf(ficresp,"\n");
1.240     brouard  5129:        }
1.251     brouard  5130:        if(first==1)
                   5131:          printf("Others in log...\n");
                   5132:        fprintf(ficlog,"\n");
                   5133:       } /* end loop age iage */
1.265     brouard  5134:       
1.251     brouard  5135:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  5136:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  5137:        if(posproptt < 1.e-5){
1.265     brouard  5138:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  5139:        }else{
1.265     brouard  5140:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  5141:        }
1.226     brouard  5142:       }
1.251     brouard  5143:       fprintf(ficresphtm,"</tr>\n");
                   5144:       fprintf(ficresphtm,"</table>\n");
                   5145:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  5146:       if(posproptt < 1.e-5){
1.251     brouard  5147:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   5148:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  5149:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   5150:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  5151:        invalidvarcomb[j1]=1;
1.226     brouard  5152:       }else{
1.251     brouard  5153:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   5154:        invalidvarcomb[j1]=0;
1.226     brouard  5155:       }
1.251     brouard  5156:       fprintf(ficresphtmfr,"</table>\n");
                   5157:       fprintf(ficlog,"\n");
                   5158:       if(j!=0){
                   5159:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  5160:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  5161:          for(k=1; k <=(nlstate+ndeath); k++){
                   5162:            if (k != i) {
1.265     brouard  5163:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  5164:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  5165:                  if(j1==1){ /* All dummy covariates to zero */
                   5166:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   5167:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  5168:                    printf("%d%d ",i,k);
                   5169:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  5170:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   5171:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   5172:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  5173:                  }
1.253     brouard  5174:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   5175:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   5176:                    x[iage]= (double)iage;
                   5177:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  5178:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  5179:                  }
1.268     brouard  5180:                  /* Some are not finite, but linreg will ignore these ages */
                   5181:                  no=0;
1.253     brouard  5182:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  5183:                  pstart[s1]=b;
                   5184:                  pstart[s1-1]=a;
1.252     brouard  5185:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   5186:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   5187:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  5188:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  5189:                  printf("%d%d ",i,k);
                   5190:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  5191:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  5192:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   5193:                  ;
                   5194:                }
                   5195:                /* printf("%12.7f )", param[i][jj][k]); */
                   5196:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5197:                s1++; 
1.251     brouard  5198:              } /* end jj */
                   5199:            } /* end k!= i */
                   5200:          } /* end k */
1.265     brouard  5201:        } /* end i, s1 */
1.251     brouard  5202:       } /* end j !=0 */
                   5203:     } /* end selected combination of covariate j1 */
                   5204:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   5205:       printf("#Freqsummary: Starting values for the constants:\n");
                   5206:       fprintf(ficlog,"\n");
1.265     brouard  5207:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  5208:        for(k=1; k <=(nlstate+ndeath); k++){
                   5209:          if (k != i) {
                   5210:            printf("%d%d ",i,k);
                   5211:            fprintf(ficlog,"%d%d ",i,k);
                   5212:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  5213:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  5214:              if(jj==1){ /* Age has to be done */
1.265     brouard  5215:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   5216:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   5217:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  5218:              }
                   5219:              /* printf("%12.7f )", param[i][jj][k]); */
                   5220:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5221:              s1++; 
1.250     brouard  5222:            }
1.251     brouard  5223:            printf("\n");
                   5224:            fprintf(ficlog,"\n");
1.250     brouard  5225:          }
                   5226:        }
1.284     brouard  5227:       } /* end of state i */
1.251     brouard  5228:       printf("#Freqsummary\n");
                   5229:       fprintf(ficlog,"\n");
1.265     brouard  5230:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   5231:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   5232:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   5233:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5234:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5235:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   5236:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   5237:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  5238:          /* } */
                   5239:        }
1.265     brouard  5240:       } /* end loop s1 */
1.251     brouard  5241:       
                   5242:       printf("\n");
                   5243:       fprintf(ficlog,"\n");
                   5244:     } /* end j=0 */
1.249     brouard  5245:   } /* end j */
1.252     brouard  5246: 
1.253     brouard  5247:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  5248:     for(i=1, jk=1; i <=nlstate; i++){
                   5249:       for(j=1; j <=nlstate+ndeath; j++){
                   5250:        if(j!=i){
                   5251:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   5252:          printf("%1d%1d",i,j);
                   5253:          fprintf(ficparo,"%1d%1d",i,j);
                   5254:          for(k=1; k<=ncovmodel;k++){
                   5255:            /*    printf(" %lf",param[i][j][k]); */
                   5256:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   5257:            p[jk]=pstart[jk];
                   5258:            printf(" %f ",pstart[jk]);
                   5259:            fprintf(ficparo," %f ",pstart[jk]);
                   5260:            jk++;
                   5261:          }
                   5262:          printf("\n");
                   5263:          fprintf(ficparo,"\n");
                   5264:        }
                   5265:       }
                   5266:     }
                   5267:   } /* end mle=-2 */
1.226     brouard  5268:   dateintmean=dateintsum/k2cpt; 
1.296     brouard  5269:   date2dmy(dateintmean,&jintmean,&mintmean,&aintmean);
1.240     brouard  5270:   
1.226     brouard  5271:   fclose(ficresp);
                   5272:   fclose(ficresphtm);
                   5273:   fclose(ficresphtmfr);
1.283     brouard  5274:   free_vector(idq,1,nqfveff);
1.226     brouard  5275:   free_vector(meanq,1,nqfveff);
1.284     brouard  5276:   free_vector(stdq,1,nqfveff);
1.226     brouard  5277:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  5278:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   5279:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  5280:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5281:   free_vector(pospropt,1,nlstate);
                   5282:   free_vector(posprop,1,nlstate);
1.251     brouard  5283:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5284:   free_vector(pp,1,nlstate);
                   5285:   /* End of freqsummary */
                   5286: }
1.126     brouard  5287: 
1.268     brouard  5288: /* Simple linear regression */
                   5289: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   5290: 
                   5291:   /* y=a+bx regression */
                   5292:   double   sumx = 0.0;                        /* sum of x                      */
                   5293:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   5294:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   5295:   double   sumy = 0.0;                        /* sum of y                      */
                   5296:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   5297:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   5298:   double yhat;
                   5299:   
                   5300:   double denom=0;
                   5301:   int i;
                   5302:   int ne=*no;
                   5303:   
                   5304:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5305:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5306:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5307:       continue;
                   5308:     }
                   5309:     ne=ne+1;
                   5310:     sumx  += x[i];       
                   5311:     sumx2 += x[i]*x[i];  
                   5312:     sumxy += x[i] * y[i];
                   5313:     sumy  += y[i];      
                   5314:     sumy2 += y[i]*y[i]; 
                   5315:     denom = (ne * sumx2 - sumx*sumx);
                   5316:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5317:   } 
                   5318:   
                   5319:   denom = (ne * sumx2 - sumx*sumx);
                   5320:   if (denom == 0) {
                   5321:     // vertical, slope m is infinity
                   5322:     *b = INFINITY;
                   5323:     *a = 0;
                   5324:     if (r) *r = 0;
                   5325:     return 1;
                   5326:   }
                   5327:   
                   5328:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5329:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5330:   if (r!=NULL) {
                   5331:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5332:       sqrt((sumx2 - sumx*sumx/ne) *
                   5333:           (sumy2 - sumy*sumy/ne));
                   5334:   }
                   5335:   *no=ne;
                   5336:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5337:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5338:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5339:       continue;
                   5340:     }
                   5341:     ne=ne+1;
                   5342:     yhat = y[i] - *a -*b* x[i];
                   5343:     sume2  += yhat * yhat ;       
                   5344:     
                   5345:     denom = (ne * sumx2 - sumx*sumx);
                   5346:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5347:   } 
                   5348:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5349:   *sa= *sb * sqrt(sumx2/ne);
                   5350:   
                   5351:   return 0; 
                   5352: }
                   5353: 
1.126     brouard  5354: /************ Prevalence ********************/
1.227     brouard  5355: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5356: {  
                   5357:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5358:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5359:      We still use firstpass and lastpass as another selection.
                   5360:   */
1.126     brouard  5361:  
1.227     brouard  5362:   int i, m, jk, j1, bool, z1,j, iv;
                   5363:   int mi; /* Effective wave */
                   5364:   int iage;
                   5365:   double agebegin, ageend;
                   5366: 
                   5367:   double **prop;
                   5368:   double posprop; 
                   5369:   double  y2; /* in fractional years */
                   5370:   int iagemin, iagemax;
                   5371:   int first; /** to stop verbosity which is redirected to log file */
                   5372: 
                   5373:   iagemin= (int) agemin;
                   5374:   iagemax= (int) agemax;
                   5375:   /*pp=vector(1,nlstate);*/
1.251     brouard  5376:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5377:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5378:   j1=0;
1.222     brouard  5379:   
1.227     brouard  5380:   /*j=cptcoveff;*/
                   5381:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5382:   
1.288     brouard  5383:   first=0;
1.227     brouard  5384:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5385:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5386:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5387:        prop[i][iage]=0.0;
                   5388:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5389:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5390:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5391:     
                   5392:     for (i=1; i<=imx; i++) { /* Each individual */
                   5393:       bool=1;
                   5394:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5395:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5396:        m=mw[mi][i];
                   5397:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5398:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5399:        for (z1=1; z1<=cptcoveff; z1++){
                   5400:          if( Fixed[Tmodelind[z1]]==1){
                   5401:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5402:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5403:              bool=0;
                   5404:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5405:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5406:              bool=0;
                   5407:            }
                   5408:        }
                   5409:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5410:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5411:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5412:          if(m >=firstpass && m <=lastpass){
                   5413:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5414:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5415:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5416:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5417:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5418:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5419:                exit(1);
                   5420:              }
                   5421:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5422:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5423:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5424:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5425:              } /* end valid statuses */ 
                   5426:            } /* end selection of dates */
                   5427:          } /* end selection of waves */
                   5428:        } /* end bool */
                   5429:       } /* end wave */
                   5430:     } /* end individual */
                   5431:     for(i=iagemin; i <= iagemax+3; i++){  
                   5432:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5433:        posprop += prop[jk][i]; 
                   5434:       } 
                   5435:       
                   5436:       for(jk=1; jk <=nlstate ; jk++){      
                   5437:        if( i <=  iagemax){ 
                   5438:          if(posprop>=1.e-5){ 
                   5439:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5440:          } else{
1.288     brouard  5441:            if(!first){
                   5442:              first=1;
1.266     brouard  5443:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5444:            }else{
1.288     brouard  5445:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5446:            }
                   5447:          }
                   5448:        } 
                   5449:       }/* end jk */ 
                   5450:     }/* end i */ 
1.222     brouard  5451:      /*} *//* end i1 */
1.227     brouard  5452:   } /* end j1 */
1.222     brouard  5453:   
1.227     brouard  5454:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5455:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5456:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5457: }  /* End of prevalence */
1.126     brouard  5458: 
                   5459: /************* Waves Concatenation ***************/
                   5460: 
                   5461: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5462: {
1.298     brouard  5463:   /* Concatenates waves: wav[i] is the number of effective (useful waves in the sense that a non interview is useless) of individual i.
1.126     brouard  5464:      Death is a valid wave (if date is known).
                   5465:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5466:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
1.298     brouard  5467:      and mw[mi+1][i]. dh depends on stepm. s[m][i] exists for any wave from firstpass to lastpass
1.227     brouard  5468:   */
1.126     brouard  5469: 
1.224     brouard  5470:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5471:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5472:      double sum=0., jmean=0.;*/
1.224     brouard  5473:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5474:   int j, k=0,jk, ju, jl;
                   5475:   double sum=0.;
                   5476:   first=0;
1.214     brouard  5477:   firstwo=0;
1.217     brouard  5478:   firsthree=0;
1.218     brouard  5479:   firstfour=0;
1.164     brouard  5480:   jmin=100000;
1.126     brouard  5481:   jmax=-1;
                   5482:   jmean=0.;
1.224     brouard  5483: 
                   5484: /* Treating live states */
1.214     brouard  5485:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5486:     mi=0;  /* First valid wave */
1.227     brouard  5487:     mli=0; /* Last valid wave */
1.309     brouard  5488:     m=firstpass;  /* Loop on waves */
                   5489:     while(s[m][i] <= nlstate){  /* a live state or unknown state  */
1.227     brouard  5490:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5491:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5492:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
1.309     brouard  5493:        mw[++mi][i]=m; /* Valid wave: incrementing mi and updating mi; mw[mi] is the wave number of mi_th valid transition   */
1.227     brouard  5494:        mli=m;
1.224     brouard  5495:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5496:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5497:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5498:       }
1.309     brouard  5499:       else{ /* m = lastpass, eventual special issue with warning */
1.224     brouard  5500: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5501:        break;
1.224     brouard  5502: #else
1.317     brouard  5503:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){ /* no death date and known date of interview, case -2 (vital status unknown is warned later */
1.227     brouard  5504:          if(firsthree == 0){
1.302     brouard  5505:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5506:            firsthree=1;
1.317     brouard  5507:          }else if(firsthree >=1 && firsthree < 10){
                   5508:            fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
                   5509:            firsthree++;
                   5510:          }else if(firsthree == 10){
                   5511:            printf("Information, too many Information flags: no more reported to log either\n");
                   5512:            fprintf(ficlog,"Information, too many Information flags: no more reported to log either\n");
                   5513:            firsthree++;
                   5514:          }else{
                   5515:            firsthree++;
1.227     brouard  5516:          }
1.309     brouard  5517:          mw[++mi][i]=m; /* Valid transition with unknown status */
1.227     brouard  5518:          mli=m;
                   5519:        }
                   5520:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5521:          nbwarn++;
1.309     brouard  5522:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified?not a transition */
1.227     brouard  5523:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5524:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5525:          }
                   5526:          break;
                   5527:        }
                   5528:        break;
1.224     brouard  5529: #endif
1.227     brouard  5530:       }/* End m >= lastpass */
1.126     brouard  5531:     }/* end while */
1.224     brouard  5532: 
1.227     brouard  5533:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5534:     /* After last pass */
1.224     brouard  5535: /* Treating death states */
1.214     brouard  5536:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5537:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5538:       /* } */
1.126     brouard  5539:       mi++;    /* Death is another wave */
                   5540:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5541:       /* Only death is a correct wave */
1.126     brouard  5542:       mw[mi][i]=m;
1.257     brouard  5543:     } /* else not in a death state */
1.224     brouard  5544: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5545:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5546:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.309     brouard  5547:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* month of death occured before last wave month and status should have been death instead of -1 */
1.227     brouard  5548:          nbwarn++;
                   5549:          if(firstfiv==0){
1.309     brouard  5550:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5551:            firstfiv=1;
                   5552:          }else{
1.309     brouard  5553:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5554:          }
1.309     brouard  5555:            s[m][i]=nlstate+1; /* Fixing the status as death. Be careful if multiple death states */
                   5556:        }else{ /* Month of Death occured afer last wave month, potential bias */
1.227     brouard  5557:          nberr++;
                   5558:          if(firstwo==0){
1.309     brouard  5559:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5560:            firstwo=1;
                   5561:          }
1.309     brouard  5562:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5563:        }
1.257     brouard  5564:       }else{ /* if date of interview is unknown */
1.227     brouard  5565:        /* death is known but not confirmed by death status at any wave */
                   5566:        if(firstfour==0){
1.309     brouard  5567:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5568:          firstfour=1;
                   5569:        }
1.309     brouard  5570:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d  with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.214     brouard  5571:       }
1.224     brouard  5572:     } /* end if date of death is known */
                   5573: #endif
1.309     brouard  5574:     wav[i]=mi; /* mi should be the last effective wave (or mli),  */
                   5575:     /* wav[i]=mw[mi][i];   */
1.126     brouard  5576:     if(mi==0){
                   5577:       nbwarn++;
                   5578:       if(first==0){
1.227     brouard  5579:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5580:        first=1;
1.126     brouard  5581:       }
                   5582:       if(first==1){
1.227     brouard  5583:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5584:       }
                   5585:     } /* end mi==0 */
                   5586:   } /* End individuals */
1.214     brouard  5587:   /* wav and mw are no more changed */
1.223     brouard  5588:        
1.317     brouard  5589:   printf("Information, you have to check %d informations which haven't been logged!\n",firsthree);
                   5590:   fprintf(ficlog,"Information, you have to check %d informations which haven't been logged!\n",firsthree);
                   5591: 
                   5592: 
1.126     brouard  5593:   for(i=1; i<=imx; i++){
                   5594:     for(mi=1; mi<wav[i];mi++){
                   5595:       if (stepm <=0)
1.227     brouard  5596:        dh[mi][i]=1;
1.126     brouard  5597:       else{
1.260     brouard  5598:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5599:          if (agedc[i] < 2*AGESUP) {
                   5600:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5601:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5602:            else if(j<0){
                   5603:              nberr++;
                   5604:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5605:              j=1; /* Temporary Dangerous patch */
                   5606:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5607:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5608:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5609:            }
                   5610:            k=k+1;
                   5611:            if (j >= jmax){
                   5612:              jmax=j;
                   5613:              ijmax=i;
                   5614:            }
                   5615:            if (j <= jmin){
                   5616:              jmin=j;
                   5617:              ijmin=i;
                   5618:            }
                   5619:            sum=sum+j;
                   5620:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5621:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5622:          }
                   5623:        }
                   5624:        else{
                   5625:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5626: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5627:                                        
1.227     brouard  5628:          k=k+1;
                   5629:          if (j >= jmax) {
                   5630:            jmax=j;
                   5631:            ijmax=i;
                   5632:          }
                   5633:          else if (j <= jmin){
                   5634:            jmin=j;
                   5635:            ijmin=i;
                   5636:          }
                   5637:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5638:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5639:          if(j<0){
                   5640:            nberr++;
                   5641:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5642:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5643:          }
                   5644:          sum=sum+j;
                   5645:        }
                   5646:        jk= j/stepm;
                   5647:        jl= j -jk*stepm;
                   5648:        ju= j -(jk+1)*stepm;
                   5649:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5650:          if(jl==0){
                   5651:            dh[mi][i]=jk;
                   5652:            bh[mi][i]=0;
                   5653:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5654:                  * to avoid the price of an extra matrix product in likelihood */
                   5655:            dh[mi][i]=jk+1;
                   5656:            bh[mi][i]=ju;
                   5657:          }
                   5658:        }else{
                   5659:          if(jl <= -ju){
                   5660:            dh[mi][i]=jk;
                   5661:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5662:                                 * is higher than the multiple of stepm and negative otherwise.
                   5663:                                 */
                   5664:          }
                   5665:          else{
                   5666:            dh[mi][i]=jk+1;
                   5667:            bh[mi][i]=ju;
                   5668:          }
                   5669:          if(dh[mi][i]==0){
                   5670:            dh[mi][i]=1; /* At least one step */
                   5671:            bh[mi][i]=ju; /* At least one step */
                   5672:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5673:          }
                   5674:        } /* end if mle */
1.126     brouard  5675:       }
                   5676:     } /* end wave */
                   5677:   }
                   5678:   jmean=sum/k;
                   5679:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5680:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5681: }
1.126     brouard  5682: 
                   5683: /*********** Tricode ****************************/
1.220     brouard  5684:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5685:  {
                   5686:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5687:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5688:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5689:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5690:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5691:     */
1.130     brouard  5692: 
1.242     brouard  5693:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5694:    int modmaxcovj=0; /* Modality max of covariates j */
                   5695:    int cptcode=0; /* Modality max of covariates j */
                   5696:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5697: 
                   5698: 
1.242     brouard  5699:    /* cptcoveff=0;  */
                   5700:    /* *cptcov=0; */
1.126     brouard  5701:  
1.242     brouard  5702:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5703:    for (k=1; k <= maxncov; k++)
                   5704:      for(j=1; j<=2; j++)
                   5705:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5706: 
1.242     brouard  5707:    /* Loop on covariates without age and products and no quantitative variable */
                   5708:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5709:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5710:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5711:        switch(Fixed[k]) {
                   5712:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
1.311     brouard  5713:         modmaxcovj=0;
                   5714:         modmincovj=0;
1.242     brouard  5715:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5716:           ij=(int)(covar[Tvar[k]][i]);
                   5717:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5718:            * If product of Vn*Vm, still boolean *:
                   5719:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5720:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5721:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5722:              modality of the nth covariate of individual i. */
                   5723:           if (ij > modmaxcovj)
                   5724:             modmaxcovj=ij; 
                   5725:           else if (ij < modmincovj) 
                   5726:             modmincovj=ij; 
1.287     brouard  5727:           if (ij <0 || ij >1 ){
1.311     brouard  5728:             printf("ERROR, IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5729:             fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5730:             fflush(ficlog);
                   5731:             exit(1);
1.287     brouard  5732:           }
                   5733:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5734:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5735:             exit(1);
                   5736:           }else
                   5737:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5738:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5739:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5740:           /* getting the maximum value of the modality of the covariate
                   5741:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5742:              female ies 1, then modmaxcovj=1.
                   5743:           */
                   5744:         } /* end for loop on individuals i */
                   5745:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5746:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5747:         cptcode=modmaxcovj;
                   5748:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5749:         /*for (i=0; i<=cptcode; i++) {*/
                   5750:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5751:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5752:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5753:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5754:             if( j != -1){
                   5755:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5756:                                  covariate for which somebody answered excluding 
                   5757:                                  undefined. Usually 2: 0 and 1. */
                   5758:             }
                   5759:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5760:                                     covariate for which somebody answered including 
                   5761:                                     undefined. Usually 3: -1, 0 and 1. */
                   5762:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5763:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5764:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5765:                        
1.242     brouard  5766:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5767:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5768:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5769:         /* modmincovj=3; modmaxcovj = 7; */
                   5770:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5771:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5772:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5773:         /* nbcode[Tvar[j]][ij]=k; */
                   5774:         /* nbcode[Tvar[j]][1]=0; */
                   5775:         /* nbcode[Tvar[j]][2]=1; */
                   5776:         /* nbcode[Tvar[j]][3]=2; */
                   5777:         /* To be continued (not working yet). */
                   5778:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5779: 
                   5780:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5781:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5782:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5783:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5784:         /*, could be restored in the future */
                   5785:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5786:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5787:             break;
                   5788:           }
                   5789:           ij++;
1.287     brouard  5790:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5791:           cptcode = ij; /* New max modality for covar j */
                   5792:         } /* end of loop on modality i=-1 to 1 or more */
                   5793:         break;
                   5794:        case 1: /* Testing on varying covariate, could be simple and
                   5795:                * should look at waves or product of fixed *
                   5796:                * varying. No time to test -1, assuming 0 and 1 only */
                   5797:         ij=0;
                   5798:         for(i=0; i<=1;i++){
                   5799:           nbcode[Tvar[k]][++ij]=i;
                   5800:         }
                   5801:         break;
                   5802:        default:
                   5803:         break;
                   5804:        } /* end switch */
                   5805:      } /* end dummy test */
1.311     brouard  5806:      if(Dummy[k]==1 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5807:        for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5808:         if(isnan(covar[Tvar[k]][i])){
                   5809:           printf("ERROR, IMaCh doesn't treat fixed quantitative covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5810:           fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5811:           fflush(ficlog);
                   5812:           exit(1);
                   5813:          }
                   5814:        }
                   5815:      }
1.287     brouard  5816:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5817:   
                   5818:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5819:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5820:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5821:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5822:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5823:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5824:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5825:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5826:   
                   5827:    ij=0;
                   5828:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5829:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5830:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5831:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5832:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5833:        /* If product not in single variable we don't print results */
                   5834:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5835:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5836:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5837:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5838:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5839:        if(Fixed[k]!=0)
                   5840:         anyvaryingduminmodel=1;
                   5841:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5842:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5843:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5844:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5845:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5846:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5847:      } 
                   5848:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5849:    /* ij--; */
                   5850:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5851:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5852:                * because they can be excluded from the model and real
                   5853:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5854:    for(j=ij+1; j<= cptcovt; j++){
                   5855:      Tvaraff[j]=0;
                   5856:      Tmodelind[j]=0;
                   5857:    }
                   5858:    for(j=ntveff+1; j<= cptcovt; j++){
                   5859:      TmodelInvind[j]=0;
                   5860:    }
                   5861:    /* To be sorted */
                   5862:    ;
                   5863:  }
1.126     brouard  5864: 
1.145     brouard  5865: 
1.126     brouard  5866: /*********** Health Expectancies ****************/
                   5867: 
1.235     brouard  5868:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5869: 
                   5870: {
                   5871:   /* Health expectancies, no variances */
1.164     brouard  5872:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5873:   int nhstepma, nstepma; /* Decreasing with age */
                   5874:   double age, agelim, hf;
                   5875:   double ***p3mat;
                   5876:   double eip;
                   5877: 
1.238     brouard  5878:   /* pstamp(ficreseij); */
1.126     brouard  5879:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5880:   fprintf(ficreseij,"# Age");
                   5881:   for(i=1; i<=nlstate;i++){
                   5882:     for(j=1; j<=nlstate;j++){
                   5883:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5884:     }
                   5885:     fprintf(ficreseij," e%1d. ",i);
                   5886:   }
                   5887:   fprintf(ficreseij,"\n");
                   5888: 
                   5889:   
                   5890:   if(estepm < stepm){
                   5891:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5892:   }
                   5893:   else  hstepm=estepm;   
                   5894:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5895:    * This is mainly to measure the difference between two models: for example
                   5896:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5897:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5898:    * progression in between and thus overestimating or underestimating according
                   5899:    * to the curvature of the survival function. If, for the same date, we 
                   5900:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5901:    * to compare the new estimate of Life expectancy with the same linear 
                   5902:    * hypothesis. A more precise result, taking into account a more precise
                   5903:    * curvature will be obtained if estepm is as small as stepm. */
                   5904: 
                   5905:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5906:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5907:      nhstepm is the number of hstepm from age to agelim 
                   5908:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5909:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5910:      and note for a fixed period like estepm months */
                   5911:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5912:      survival function given by stepm (the optimization length). Unfortunately it
                   5913:      means that if the survival funtion is printed only each two years of age and if
                   5914:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5915:      results. So we changed our mind and took the option of the best precision.
                   5916:   */
                   5917:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5918: 
                   5919:   agelim=AGESUP;
                   5920:   /* If stepm=6 months */
                   5921:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5922:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5923:     
                   5924: /* nhstepm age range expressed in number of stepm */
                   5925:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5926:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5927:   /* if (stepm >= YEARM) hstepm=1;*/
                   5928:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5929:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5930: 
                   5931:   for (age=bage; age<=fage; age ++){ 
                   5932:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5933:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5934:     /* if (stepm >= YEARM) hstepm=1;*/
                   5935:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5936: 
                   5937:     /* If stepm=6 months */
                   5938:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5939:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5940:     
1.235     brouard  5941:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5942:     
                   5943:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5944:     
                   5945:     printf("%d|",(int)age);fflush(stdout);
                   5946:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5947:     
                   5948:     /* Computing expectancies */
                   5949:     for(i=1; i<=nlstate;i++)
                   5950:       for(j=1; j<=nlstate;j++)
                   5951:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5952:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5953:          
                   5954:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5955: 
                   5956:        }
                   5957: 
                   5958:     fprintf(ficreseij,"%3.0f",age );
                   5959:     for(i=1; i<=nlstate;i++){
                   5960:       eip=0;
                   5961:       for(j=1; j<=nlstate;j++){
                   5962:        eip +=eij[i][j][(int)age];
                   5963:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5964:       }
                   5965:       fprintf(ficreseij,"%9.4f", eip );
                   5966:     }
                   5967:     fprintf(ficreseij,"\n");
                   5968:     
                   5969:   }
                   5970:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5971:   printf("\n");
                   5972:   fprintf(ficlog,"\n");
                   5973:   
                   5974: }
                   5975: 
1.235     brouard  5976:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5977: 
                   5978: {
                   5979:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5980:      to initial status i, ei. .
1.126     brouard  5981:   */
                   5982:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5983:   int nhstepma, nstepma; /* Decreasing with age */
                   5984:   double age, agelim, hf;
                   5985:   double ***p3matp, ***p3matm, ***varhe;
                   5986:   double **dnewm,**doldm;
                   5987:   double *xp, *xm;
                   5988:   double **gp, **gm;
                   5989:   double ***gradg, ***trgradg;
                   5990:   int theta;
                   5991: 
                   5992:   double eip, vip;
                   5993: 
                   5994:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5995:   xp=vector(1,npar);
                   5996:   xm=vector(1,npar);
                   5997:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5998:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5999:   
                   6000:   pstamp(ficresstdeij);
                   6001:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   6002:   fprintf(ficresstdeij,"# Age");
                   6003:   for(i=1; i<=nlstate;i++){
                   6004:     for(j=1; j<=nlstate;j++)
                   6005:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   6006:     fprintf(ficresstdeij," e%1d. ",i);
                   6007:   }
                   6008:   fprintf(ficresstdeij,"\n");
                   6009: 
                   6010:   pstamp(ficrescveij);
                   6011:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   6012:   fprintf(ficrescveij,"# Age");
                   6013:   for(i=1; i<=nlstate;i++)
                   6014:     for(j=1; j<=nlstate;j++){
                   6015:       cptj= (j-1)*nlstate+i;
                   6016:       for(i2=1; i2<=nlstate;i2++)
                   6017:        for(j2=1; j2<=nlstate;j2++){
                   6018:          cptj2= (j2-1)*nlstate+i2;
                   6019:          if(cptj2 <= cptj)
                   6020:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   6021:        }
                   6022:     }
                   6023:   fprintf(ficrescveij,"\n");
                   6024:   
                   6025:   if(estepm < stepm){
                   6026:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   6027:   }
                   6028:   else  hstepm=estepm;   
                   6029:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   6030:    * This is mainly to measure the difference between two models: for example
                   6031:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   6032:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   6033:    * progression in between and thus overestimating or underestimating according
                   6034:    * to the curvature of the survival function. If, for the same date, we 
                   6035:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   6036:    * to compare the new estimate of Life expectancy with the same linear 
                   6037:    * hypothesis. A more precise result, taking into account a more precise
                   6038:    * curvature will be obtained if estepm is as small as stepm. */
                   6039: 
                   6040:   /* For example we decided to compute the life expectancy with the smallest unit */
                   6041:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6042:      nhstepm is the number of hstepm from age to agelim 
                   6043:      nstepm is the number of stepm from age to agelin. 
                   6044:      Look at hpijx to understand the reason of that which relies in memory size
                   6045:      and note for a fixed period like estepm months */
                   6046:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   6047:      survival function given by stepm (the optimization length). Unfortunately it
                   6048:      means that if the survival funtion is printed only each two years of age and if
                   6049:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6050:      results. So we changed our mind and took the option of the best precision.
                   6051:   */
                   6052:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6053: 
                   6054:   /* If stepm=6 months */
                   6055:   /* nhstepm age range expressed in number of stepm */
                   6056:   agelim=AGESUP;
                   6057:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   6058:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   6059:   /* if (stepm >= YEARM) hstepm=1;*/
                   6060:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6061:   
                   6062:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6063:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6064:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   6065:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   6066:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   6067:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   6068: 
                   6069:   for (age=bage; age<=fage; age ++){ 
                   6070:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   6071:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   6072:     /* if (stepm >= YEARM) hstepm=1;*/
                   6073:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  6074:                
1.126     brouard  6075:     /* If stepm=6 months */
                   6076:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   6077:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   6078:     
                   6079:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  6080:                
1.126     brouard  6081:     /* Computing  Variances of health expectancies */
                   6082:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   6083:        decrease memory allocation */
                   6084:     for(theta=1; theta <=npar; theta++){
                   6085:       for(i=1; i<=npar; i++){ 
1.222     brouard  6086:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6087:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  6088:       }
1.235     brouard  6089:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   6090:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  6091:                        
1.126     brouard  6092:       for(j=1; j<= nlstate; j++){
1.222     brouard  6093:        for(i=1; i<=nlstate; i++){
                   6094:          for(h=0; h<=nhstepm-1; h++){
                   6095:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   6096:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   6097:          }
                   6098:        }
1.126     brouard  6099:       }
1.218     brouard  6100:                        
1.126     brouard  6101:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  6102:        for(h=0; h<=nhstepm-1; h++){
                   6103:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   6104:        }
1.126     brouard  6105:     }/* End theta */
                   6106:     
                   6107:     
                   6108:     for(h=0; h<=nhstepm-1; h++)
                   6109:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  6110:        for(theta=1; theta <=npar; theta++)
                   6111:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  6112:     
1.218     brouard  6113:                
1.222     brouard  6114:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  6115:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  6116:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  6117:                
1.222     brouard  6118:     printf("%d|",(int)age);fflush(stdout);
                   6119:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   6120:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  6121:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  6122:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   6123:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   6124:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   6125:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   6126:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  6127:       }
                   6128:     }
1.320     brouard  6129:     /* if((int)age ==50){ */
                   6130:     /*   printf(" age=%d cij=%d nres=%d varhe[%d][%d]=%f ",(int)age, cij, nres, 1,2,varhe[1][2]); */
                   6131:     /* } */
1.126     brouard  6132:     /* Computing expectancies */
1.235     brouard  6133:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  6134:     for(i=1; i<=nlstate;i++)
                   6135:       for(j=1; j<=nlstate;j++)
1.222     brouard  6136:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   6137:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  6138:                                        
1.222     brouard  6139:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  6140:                                        
1.222     brouard  6141:        }
1.269     brouard  6142: 
                   6143:     /* Standard deviation of expectancies ij */                
1.126     brouard  6144:     fprintf(ficresstdeij,"%3.0f",age );
                   6145:     for(i=1; i<=nlstate;i++){
                   6146:       eip=0.;
                   6147:       vip=0.;
                   6148:       for(j=1; j<=nlstate;j++){
1.222     brouard  6149:        eip += eij[i][j][(int)age];
                   6150:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   6151:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   6152:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  6153:       }
                   6154:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   6155:     }
                   6156:     fprintf(ficresstdeij,"\n");
1.218     brouard  6157:                
1.269     brouard  6158:     /* Variance of expectancies ij */          
1.126     brouard  6159:     fprintf(ficrescveij,"%3.0f",age );
                   6160:     for(i=1; i<=nlstate;i++)
                   6161:       for(j=1; j<=nlstate;j++){
1.222     brouard  6162:        cptj= (j-1)*nlstate+i;
                   6163:        for(i2=1; i2<=nlstate;i2++)
                   6164:          for(j2=1; j2<=nlstate;j2++){
                   6165:            cptj2= (j2-1)*nlstate+i2;
                   6166:            if(cptj2 <= cptj)
                   6167:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   6168:          }
1.126     brouard  6169:       }
                   6170:     fprintf(ficrescveij,"\n");
1.218     brouard  6171:                
1.126     brouard  6172:   }
                   6173:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   6174:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   6175:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   6176:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   6177:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6178:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6179:   printf("\n");
                   6180:   fprintf(ficlog,"\n");
1.218     brouard  6181:        
1.126     brouard  6182:   free_vector(xm,1,npar);
                   6183:   free_vector(xp,1,npar);
                   6184:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   6185:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   6186:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   6187: }
1.218     brouard  6188:  
1.126     brouard  6189: /************ Variance ******************/
1.235     brouard  6190:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  6191:  {
1.279     brouard  6192:    /** Variance of health expectancies 
                   6193:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   6194:     * double **newm;
                   6195:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   6196:     */
1.218     brouard  6197:   
                   6198:    /* int movingaverage(); */
                   6199:    double **dnewm,**doldm;
                   6200:    double **dnewmp,**doldmp;
                   6201:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  6202:    int first=0;
1.218     brouard  6203:    int k;
                   6204:    double *xp;
1.279     brouard  6205:    double **gp, **gm;  /**< for var eij */
                   6206:    double ***gradg, ***trgradg; /**< for var eij */
                   6207:    double **gradgp, **trgradgp; /**< for var p point j */
                   6208:    double *gpp, *gmp; /**< for var p point j */
                   6209:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  6210:    double ***p3mat;
                   6211:    double age,agelim, hf;
                   6212:    /* double ***mobaverage; */
                   6213:    int theta;
                   6214:    char digit[4];
                   6215:    char digitp[25];
                   6216: 
                   6217:    char fileresprobmorprev[FILENAMELENGTH];
                   6218: 
                   6219:    if(popbased==1){
                   6220:      if(mobilav!=0)
                   6221:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   6222:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   6223:    }
                   6224:    else 
                   6225:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  6226: 
1.218     brouard  6227:    /* if (mobilav!=0) { */
                   6228:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6229:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   6230:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   6231:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   6232:    /*   } */
                   6233:    /* } */
                   6234: 
                   6235:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   6236:    sprintf(digit,"%-d",ij);
                   6237:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   6238:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   6239:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   6240:    strcat(fileresprobmorprev,fileresu);
                   6241:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   6242:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   6243:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   6244:    }
                   6245:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6246:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6247:    pstamp(ficresprobmorprev);
                   6248:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  6249:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   6250:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   6251:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   6252:    }
                   6253:    for(j=1;j<=cptcoveff;j++) 
                   6254:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   6255:    fprintf(ficresprobmorprev,"\n");
                   6256: 
1.218     brouard  6257:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   6258:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6259:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   6260:      for(i=1; i<=nlstate;i++)
                   6261:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   6262:    }  
                   6263:    fprintf(ficresprobmorprev,"\n");
                   6264:   
                   6265:    fprintf(ficgp,"\n# Routine varevsij");
                   6266:    fprintf(ficgp,"\nunset title \n");
                   6267:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   6268:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   6269:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  6270: 
1.218     brouard  6271:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6272:    pstamp(ficresvij);
                   6273:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   6274:    if(popbased==1)
                   6275:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   6276:    else
                   6277:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   6278:    fprintf(ficresvij,"# Age");
                   6279:    for(i=1; i<=nlstate;i++)
                   6280:      for(j=1; j<=nlstate;j++)
                   6281:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   6282:    fprintf(ficresvij,"\n");
                   6283: 
                   6284:    xp=vector(1,npar);
                   6285:    dnewm=matrix(1,nlstate,1,npar);
                   6286:    doldm=matrix(1,nlstate,1,nlstate);
                   6287:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   6288:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6289: 
                   6290:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   6291:    gpp=vector(nlstate+1,nlstate+ndeath);
                   6292:    gmp=vector(nlstate+1,nlstate+ndeath);
                   6293:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  6294:   
1.218     brouard  6295:    if(estepm < stepm){
                   6296:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   6297:    }
                   6298:    else  hstepm=estepm;   
                   6299:    /* For example we decided to compute the life expectancy with the smallest unit */
                   6300:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6301:       nhstepm is the number of hstepm from age to agelim 
                   6302:       nstepm is the number of stepm from age to agelim. 
                   6303:       Look at function hpijx to understand why because of memory size limitations, 
                   6304:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   6305:       survival function given by stepm (the optimization length). Unfortunately it
                   6306:       means that if the survival funtion is printed every two years of age and if
                   6307:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6308:       results. So we changed our mind and took the option of the best precision.
                   6309:    */
                   6310:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6311:    agelim = AGESUP;
                   6312:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6313:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6314:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6315:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6316:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   6317:      gp=matrix(0,nhstepm,1,nlstate);
                   6318:      gm=matrix(0,nhstepm,1,nlstate);
                   6319:                
                   6320:                
                   6321:      for(theta=1; theta <=npar; theta++){
                   6322:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   6323:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6324:        }
1.279     brouard  6325:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   6326:        * returns into prlim .
1.288     brouard  6327:        */
1.242     brouard  6328:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  6329: 
                   6330:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  6331:        if (popbased==1) {
                   6332:         if(mobilav ==0){
                   6333:           for(i=1; i<=nlstate;i++)
                   6334:             prlim[i][i]=probs[(int)age][i][ij];
                   6335:         }else{ /* mobilav */ 
                   6336:           for(i=1; i<=nlstate;i++)
                   6337:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6338:         }
                   6339:        }
1.295     brouard  6340:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}x\f$ at horizon h.
1.279     brouard  6341:        */                      
                   6342:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
1.292     brouard  6343:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}x\f$, which are the probability
1.279     brouard  6344:        * at horizon h in state j including mortality.
                   6345:        */
1.218     brouard  6346:        for(j=1; j<= nlstate; j++){
                   6347:         for(h=0; h<=nhstepm; h++){
                   6348:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6349:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6350:         }
                   6351:        }
1.279     brouard  6352:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6353:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6354:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6355:        */
                   6356:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6357:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6358:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6359:        }
                   6360:        
                   6361:        /* Again with minus shift */
1.218     brouard  6362:                        
                   6363:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6364:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6365: 
1.242     brouard  6366:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6367:                        
                   6368:        if (popbased==1) {
                   6369:         if(mobilav ==0){
                   6370:           for(i=1; i<=nlstate;i++)
                   6371:             prlim[i][i]=probs[(int)age][i][ij];
                   6372:         }else{ /* mobilav */ 
                   6373:           for(i=1; i<=nlstate;i++)
                   6374:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6375:         }
                   6376:        }
                   6377:                        
1.235     brouard  6378:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6379:                        
                   6380:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6381:         for(h=0; h<=nhstepm; h++){
                   6382:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6383:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6384:         }
                   6385:        }
                   6386:        /* This for computing probability of death (h=1 means
                   6387:          computed over hstepm matrices product = hstepm*stepm months) 
                   6388:          as a weighted average of prlim.
                   6389:        */
                   6390:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6391:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6392:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6393:        }    
1.279     brouard  6394:        /* end shifting computations */
                   6395: 
                   6396:        /**< Computing gradient matrix at horizon h 
                   6397:        */
1.218     brouard  6398:        for(j=1; j<= nlstate; j++) /* vareij */
                   6399:         for(h=0; h<=nhstepm; h++){
                   6400:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6401:         }
1.279     brouard  6402:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6403:        */
                   6404:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6405:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6406:        }
                   6407:                        
                   6408:      } /* End theta */
1.279     brouard  6409:      
                   6410:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6411:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6412:                
                   6413:      for(h=0; h<=nhstepm; h++) /* veij */
                   6414:        for(j=1; j<=nlstate;j++)
                   6415:         for(theta=1; theta <=npar; theta++)
                   6416:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6417:                
                   6418:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6419:        for(theta=1; theta <=npar; theta++)
                   6420:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6421:      /**< as well as its transposed matrix 
                   6422:       */               
1.218     brouard  6423:                
                   6424:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6425:      for(i=1;i<=nlstate;i++)
                   6426:        for(j=1;j<=nlstate;j++)
                   6427:         vareij[i][j][(int)age] =0.;
1.279     brouard  6428: 
                   6429:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6430:       * and k (nhstepm) formula 15 of article
                   6431:       * Lievre-Brouard-Heathcote
                   6432:       */
                   6433:      
1.218     brouard  6434:      for(h=0;h<=nhstepm;h++){
                   6435:        for(k=0;k<=nhstepm;k++){
                   6436:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6437:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6438:         for(i=1;i<=nlstate;i++)
                   6439:           for(j=1;j<=nlstate;j++)
                   6440:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6441:        }
                   6442:      }
                   6443:                
1.279     brouard  6444:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6445:       * p.j overall mortality formula 49 but computed directly because
                   6446:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6447:       * wix is independent of theta.
                   6448:       */
1.218     brouard  6449:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6450:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6451:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6452:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6453:         varppt[j][i]=doldmp[j][i];
                   6454:      /* end ppptj */
                   6455:      /*  x centered again */
                   6456:                
1.242     brouard  6457:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6458:                
                   6459:      if (popbased==1) {
                   6460:        if(mobilav ==0){
                   6461:         for(i=1; i<=nlstate;i++)
                   6462:           prlim[i][i]=probs[(int)age][i][ij];
                   6463:        }else{ /* mobilav */ 
                   6464:         for(i=1; i<=nlstate;i++)
                   6465:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6466:        }
                   6467:      }
                   6468:                
                   6469:      /* This for computing probability of death (h=1 means
                   6470:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6471:        as a weighted average of prlim.
                   6472:      */
1.235     brouard  6473:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6474:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6475:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6476:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6477:      }    
                   6478:      /* end probability of death */
                   6479:                
                   6480:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6481:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6482:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6483:        for(i=1; i<=nlstate;i++){
                   6484:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6485:        }
                   6486:      } 
                   6487:      fprintf(ficresprobmorprev,"\n");
                   6488:                
                   6489:      fprintf(ficresvij,"%.0f ",age );
                   6490:      for(i=1; i<=nlstate;i++)
                   6491:        for(j=1; j<=nlstate;j++){
                   6492:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6493:        }
                   6494:      fprintf(ficresvij,"\n");
                   6495:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6496:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6497:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6498:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6499:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6500:    } /* End age */
                   6501:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6502:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6503:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6504:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6505:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6506:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6507:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6508:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6509:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6510:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6511:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6512:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6513:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6514:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6515:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6516:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6517:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6518:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6519:     */
1.218     brouard  6520:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6521:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6522: 
1.218     brouard  6523:    free_vector(xp,1,npar);
                   6524:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6525:    free_matrix(dnewm,1,nlstate,1,npar);
                   6526:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6527:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6528:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6529:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6530:    fclose(ficresprobmorprev);
                   6531:    fflush(ficgp);
                   6532:    fflush(fichtm); 
                   6533:  }  /* end varevsij */
1.126     brouard  6534: 
                   6535: /************ Variance of prevlim ******************/
1.269     brouard  6536:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6537: {
1.205     brouard  6538:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6539:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6540: 
1.268     brouard  6541:   double **dnewmpar,**doldm;
1.126     brouard  6542:   int i, j, nhstepm, hstepm;
                   6543:   double *xp;
                   6544:   double *gp, *gm;
                   6545:   double **gradg, **trgradg;
1.208     brouard  6546:   double **mgm, **mgp;
1.126     brouard  6547:   double age,agelim;
                   6548:   int theta;
                   6549:   
                   6550:   pstamp(ficresvpl);
1.288     brouard  6551:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6552:   fprintf(ficresvpl,"# Age ");
                   6553:   if(nresult >=1)
                   6554:     fprintf(ficresvpl," Result# ");
1.126     brouard  6555:   for(i=1; i<=nlstate;i++)
                   6556:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6557:   fprintf(ficresvpl,"\n");
                   6558: 
                   6559:   xp=vector(1,npar);
1.268     brouard  6560:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6561:   doldm=matrix(1,nlstate,1,nlstate);
                   6562:   
                   6563:   hstepm=1*YEARM; /* Every year of age */
                   6564:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6565:   agelim = AGESUP;
                   6566:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6567:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6568:     if (stepm >= YEARM) hstepm=1;
                   6569:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6570:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6571:     mgp=matrix(1,npar,1,nlstate);
                   6572:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6573:     gp=vector(1,nlstate);
                   6574:     gm=vector(1,nlstate);
                   6575: 
                   6576:     for(theta=1; theta <=npar; theta++){
                   6577:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6578:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6579:       }
1.288     brouard  6580:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6581:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6582:       /* else */
                   6583:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6584:       for(i=1;i<=nlstate;i++){
1.126     brouard  6585:        gp[i] = prlim[i][i];
1.208     brouard  6586:        mgp[theta][i] = prlim[i][i];
                   6587:       }
1.126     brouard  6588:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6589:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6590:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6591:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6592:       /* else */
                   6593:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6594:       for(i=1;i<=nlstate;i++){
1.126     brouard  6595:        gm[i] = prlim[i][i];
1.208     brouard  6596:        mgm[theta][i] = prlim[i][i];
                   6597:       }
1.126     brouard  6598:       for(i=1;i<=nlstate;i++)
                   6599:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6600:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6601:     } /* End theta */
                   6602: 
                   6603:     trgradg =matrix(1,nlstate,1,npar);
                   6604: 
                   6605:     for(j=1; j<=nlstate;j++)
                   6606:       for(theta=1; theta <=npar; theta++)
                   6607:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6608:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6609:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6610:     /*   for(j=1; j<=nlstate;j++){ */
                   6611:     /*         printf(" %d ",j); */
                   6612:     /*         for(theta=1; theta <=npar; theta++) */
                   6613:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6614:     /*         printf("\n "); */
                   6615:     /*   } */
                   6616:     /* } */
                   6617:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6618:     /*   printf("\n gradg %d ",(int)age); */
                   6619:     /*   for(j=1; j<=nlstate;j++){ */
                   6620:     /*         printf("%d ",j); */
                   6621:     /*         for(theta=1; theta <=npar; theta++) */
                   6622:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6623:     /*         printf("\n "); */
                   6624:     /*   } */
                   6625:     /* } */
1.126     brouard  6626: 
                   6627:     for(i=1;i<=nlstate;i++)
                   6628:       varpl[i][(int)age] =0.;
1.209     brouard  6629:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6630:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6631:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6632:     }else{
1.268     brouard  6633:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6634:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6635:     }
1.126     brouard  6636:     for(i=1;i<=nlstate;i++)
                   6637:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6638: 
                   6639:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6640:     if(nresult >=1)
                   6641:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6642:     for(i=1; i<=nlstate;i++){
1.126     brouard  6643:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6644:       /* for(j=1;j<=nlstate;j++) */
                   6645:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6646:     }
1.126     brouard  6647:     fprintf(ficresvpl,"\n");
                   6648:     free_vector(gp,1,nlstate);
                   6649:     free_vector(gm,1,nlstate);
1.208     brouard  6650:     free_matrix(mgm,1,npar,1,nlstate);
                   6651:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6652:     free_matrix(gradg,1,npar,1,nlstate);
                   6653:     free_matrix(trgradg,1,nlstate,1,npar);
                   6654:   } /* End age */
                   6655: 
                   6656:   free_vector(xp,1,npar);
                   6657:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6658:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6659: 
                   6660: }
                   6661: 
                   6662: 
                   6663: /************ Variance of backprevalence limit ******************/
1.269     brouard  6664:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6665: {
                   6666:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6667:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6668: 
                   6669:   double **dnewmpar,**doldm;
                   6670:   int i, j, nhstepm, hstepm;
                   6671:   double *xp;
                   6672:   double *gp, *gm;
                   6673:   double **gradg, **trgradg;
                   6674:   double **mgm, **mgp;
                   6675:   double age,agelim;
                   6676:   int theta;
                   6677:   
                   6678:   pstamp(ficresvbl);
                   6679:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6680:   fprintf(ficresvbl,"# Age ");
                   6681:   if(nresult >=1)
                   6682:     fprintf(ficresvbl," Result# ");
                   6683:   for(i=1; i<=nlstate;i++)
                   6684:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6685:   fprintf(ficresvbl,"\n");
                   6686: 
                   6687:   xp=vector(1,npar);
                   6688:   dnewmpar=matrix(1,nlstate,1,npar);
                   6689:   doldm=matrix(1,nlstate,1,nlstate);
                   6690:   
                   6691:   hstepm=1*YEARM; /* Every year of age */
                   6692:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6693:   agelim = AGEINF;
                   6694:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6695:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6696:     if (stepm >= YEARM) hstepm=1;
                   6697:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6698:     gradg=matrix(1,npar,1,nlstate);
                   6699:     mgp=matrix(1,npar,1,nlstate);
                   6700:     mgm=matrix(1,npar,1,nlstate);
                   6701:     gp=vector(1,nlstate);
                   6702:     gm=vector(1,nlstate);
                   6703: 
                   6704:     for(theta=1; theta <=npar; theta++){
                   6705:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6706:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6707:       }
                   6708:       if(mobilavproj > 0 )
                   6709:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6710:       else
                   6711:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6712:       for(i=1;i<=nlstate;i++){
                   6713:        gp[i] = bprlim[i][i];
                   6714:        mgp[theta][i] = bprlim[i][i];
                   6715:       }
                   6716:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6717:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6718:        if(mobilavproj > 0 )
                   6719:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6720:        else
                   6721:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6722:       for(i=1;i<=nlstate;i++){
                   6723:        gm[i] = bprlim[i][i];
                   6724:        mgm[theta][i] = bprlim[i][i];
                   6725:       }
                   6726:       for(i=1;i<=nlstate;i++)
                   6727:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6728:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6729:     } /* End theta */
                   6730: 
                   6731:     trgradg =matrix(1,nlstate,1,npar);
                   6732: 
                   6733:     for(j=1; j<=nlstate;j++)
                   6734:       for(theta=1; theta <=npar; theta++)
                   6735:        trgradg[j][theta]=gradg[theta][j];
                   6736:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6737:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6738:     /*   for(j=1; j<=nlstate;j++){ */
                   6739:     /*         printf(" %d ",j); */
                   6740:     /*         for(theta=1; theta <=npar; theta++) */
                   6741:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6742:     /*         printf("\n "); */
                   6743:     /*   } */
                   6744:     /* } */
                   6745:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6746:     /*   printf("\n gradg %d ",(int)age); */
                   6747:     /*   for(j=1; j<=nlstate;j++){ */
                   6748:     /*         printf("%d ",j); */
                   6749:     /*         for(theta=1; theta <=npar; theta++) */
                   6750:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6751:     /*         printf("\n "); */
                   6752:     /*   } */
                   6753:     /* } */
                   6754: 
                   6755:     for(i=1;i<=nlstate;i++)
                   6756:       varbpl[i][(int)age] =0.;
                   6757:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6758:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6759:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6760:     }else{
                   6761:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6762:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6763:     }
                   6764:     for(i=1;i<=nlstate;i++)
                   6765:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6766: 
                   6767:     fprintf(ficresvbl,"%.0f ",age );
                   6768:     if(nresult >=1)
                   6769:       fprintf(ficresvbl,"%d ",nres );
                   6770:     for(i=1; i<=nlstate;i++)
                   6771:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6772:     fprintf(ficresvbl,"\n");
                   6773:     free_vector(gp,1,nlstate);
                   6774:     free_vector(gm,1,nlstate);
                   6775:     free_matrix(mgm,1,npar,1,nlstate);
                   6776:     free_matrix(mgp,1,npar,1,nlstate);
                   6777:     free_matrix(gradg,1,npar,1,nlstate);
                   6778:     free_matrix(trgradg,1,nlstate,1,npar);
                   6779:   } /* End age */
                   6780: 
                   6781:   free_vector(xp,1,npar);
                   6782:   free_matrix(doldm,1,nlstate,1,npar);
                   6783:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6784: 
                   6785: }
                   6786: 
                   6787: /************ Variance of one-step probabilities  ******************/
                   6788: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6789:  {
                   6790:    int i, j=0,  k1, l1, tj;
                   6791:    int k2, l2, j1,  z1;
                   6792:    int k=0, l;
                   6793:    int first=1, first1, first2;
                   6794:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6795:    double **dnewm,**doldm;
                   6796:    double *xp;
                   6797:    double *gp, *gm;
                   6798:    double **gradg, **trgradg;
                   6799:    double **mu;
                   6800:    double age, cov[NCOVMAX+1];
                   6801:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6802:    int theta;
                   6803:    char fileresprob[FILENAMELENGTH];
                   6804:    char fileresprobcov[FILENAMELENGTH];
                   6805:    char fileresprobcor[FILENAMELENGTH];
                   6806:    double ***varpij;
                   6807: 
                   6808:    strcpy(fileresprob,"PROB_"); 
                   6809:    strcat(fileresprob,fileres);
                   6810:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6811:      printf("Problem with resultfile: %s\n", fileresprob);
                   6812:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6813:    }
                   6814:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6815:    strcat(fileresprobcov,fileresu);
                   6816:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6817:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6818:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6819:    }
                   6820:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6821:    strcat(fileresprobcor,fileresu);
                   6822:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6823:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6824:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6825:    }
                   6826:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6827:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6828:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6829:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6830:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6831:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6832:    pstamp(ficresprob);
                   6833:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6834:    fprintf(ficresprob,"# Age");
                   6835:    pstamp(ficresprobcov);
                   6836:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6837:    fprintf(ficresprobcov,"# Age");
                   6838:    pstamp(ficresprobcor);
                   6839:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6840:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6841: 
                   6842: 
1.222     brouard  6843:    for(i=1; i<=nlstate;i++)
                   6844:      for(j=1; j<=(nlstate+ndeath);j++){
                   6845:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6846:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6847:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6848:      }  
                   6849:    /* fprintf(ficresprob,"\n");
                   6850:       fprintf(ficresprobcov,"\n");
                   6851:       fprintf(ficresprobcor,"\n");
                   6852:    */
                   6853:    xp=vector(1,npar);
                   6854:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6855:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6856:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6857:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6858:    first=1;
                   6859:    fprintf(ficgp,"\n# Routine varprob");
                   6860:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6861:    fprintf(fichtm,"\n");
                   6862: 
1.288     brouard  6863:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6864:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6865:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6866: and drawn. It helps understanding how is the covariance between two incidences.\
                   6867:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6868:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6869: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6870: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6871: standard deviations wide on each axis. <br>\
                   6872:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6873:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6874: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6875: 
1.222     brouard  6876:    cov[1]=1;
                   6877:    /* tj=cptcoveff; */
1.225     brouard  6878:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6879:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6880:    j1=0;
1.224     brouard  6881:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6882:      if  (cptcovn>0) {
                   6883:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6884:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6885:        fprintf(ficresprob, "**********\n#\n");
                   6886:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6887:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6888:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6889:                        
1.222     brouard  6890:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6891:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6892:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6893:                        
                   6894:                        
1.222     brouard  6895:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.319     brouard  6896:        /* for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); */
                   6897:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtmcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6898:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6899:                        
1.222     brouard  6900:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6901:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6902:        fprintf(ficresprobcor, "**********\n#");    
                   6903:        if(invalidvarcomb[j1]){
                   6904:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6905:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6906:         continue;
                   6907:        }
                   6908:      }
                   6909:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6910:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6911:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6912:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6913:      for (age=bage; age<=fage; age ++){ 
                   6914:        cov[2]=age;
                   6915:        if(nagesqr==1)
                   6916:         cov[3]= age*age;
                   6917:        for (k=1; k<=cptcovn;k++) {
                   6918:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6919:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6920:                                                                    * 1  1 1 1 1
                   6921:                                                                    * 2  2 1 1 1
                   6922:                                                                    * 3  1 2 1 1
                   6923:                                                                    */
                   6924:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6925:        }
1.319     brouard  6926:        /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   6927:        /* ) p nbcode[Tvar[Tage[k]]][(1 & (ij-1) >> (k-1))+1] */
                   6928:        /*for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6929:        for (k=1; k<=cptcovage;k++)
                   6930:         cov[2+Tage[k]+nagesqr]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.222     brouard  6931:        for (k=1; k<=cptcovprod;k++)
                   6932:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6933:                        
                   6934:                        
1.222     brouard  6935:        for(theta=1; theta <=npar; theta++){
                   6936:         for(i=1; i<=npar; i++)
                   6937:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6938:                                
1.222     brouard  6939:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6940:                                
1.222     brouard  6941:         k=0;
                   6942:         for(i=1; i<= (nlstate); i++){
                   6943:           for(j=1; j<=(nlstate+ndeath);j++){
                   6944:             k=k+1;
                   6945:             gp[k]=pmmij[i][j];
                   6946:           }
                   6947:         }
1.220     brouard  6948:                                
1.222     brouard  6949:         for(i=1; i<=npar; i++)
                   6950:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6951:                                
1.222     brouard  6952:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6953:         k=0;
                   6954:         for(i=1; i<=(nlstate); i++){
                   6955:           for(j=1; j<=(nlstate+ndeath);j++){
                   6956:             k=k+1;
                   6957:             gm[k]=pmmij[i][j];
                   6958:           }
                   6959:         }
1.220     brouard  6960:                                
1.222     brouard  6961:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6962:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6963:        }
1.126     brouard  6964: 
1.222     brouard  6965:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6966:         for(theta=1; theta <=npar; theta++)
                   6967:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6968:                        
1.222     brouard  6969:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6970:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6971:                        
1.222     brouard  6972:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6973:                        
1.222     brouard  6974:        k=0;
                   6975:        for(i=1; i<=(nlstate); i++){
                   6976:         for(j=1; j<=(nlstate+ndeath);j++){
                   6977:           k=k+1;
                   6978:           mu[k][(int) age]=pmmij[i][j];
                   6979:         }
                   6980:        }
                   6981:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6982:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6983:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6984:                        
1.222     brouard  6985:        /*printf("\n%d ",(int)age);
                   6986:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6987:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6988:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6989:         }*/
1.220     brouard  6990:                        
1.222     brouard  6991:        fprintf(ficresprob,"\n%d ",(int)age);
                   6992:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6993:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6994:                        
1.222     brouard  6995:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6996:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6997:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6998:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6999:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   7000:        }
                   7001:        i=0;
                   7002:        for (k=1; k<=(nlstate);k++){
                   7003:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   7004:           i++;
                   7005:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   7006:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   7007:           for (j=1; j<=i;j++){
                   7008:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   7009:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   7010:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   7011:           }
                   7012:         }
                   7013:        }/* end of loop for state */
                   7014:      } /* end of loop for age */
                   7015:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   7016:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   7017:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   7018:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   7019:     
                   7020:      /* Confidence intervalle of pij  */
                   7021:      /*
                   7022:        fprintf(ficgp,"\nunset parametric;unset label");
                   7023:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   7024:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   7025:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   7026:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   7027:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   7028:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   7029:      */
                   7030:                
                   7031:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   7032:      first1=1;first2=2;
                   7033:      for (k2=1; k2<=(nlstate);k2++){
                   7034:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   7035:         if(l2==k2) continue;
                   7036:         j=(k2-1)*(nlstate+ndeath)+l2;
                   7037:         for (k1=1; k1<=(nlstate);k1++){
                   7038:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   7039:             if(l1==k1) continue;
                   7040:             i=(k1-1)*(nlstate+ndeath)+l1;
                   7041:             if(i<=j) continue;
                   7042:             for (age=bage; age<=fage; age ++){ 
                   7043:               if ((int)age %5==0){
                   7044:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   7045:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   7046:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   7047:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   7048:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   7049:                 c12=cv12/sqrt(v1*v2);
                   7050:                 /* Computing eigen value of matrix of covariance */
                   7051:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   7052:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   7053:                 if ((lc2 <0) || (lc1 <0) ){
                   7054:                   if(first2==1){
                   7055:                     first1=0;
                   7056:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   7057:                   }
                   7058:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   7059:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   7060:                   /* lc2=fabs(lc2); */
                   7061:                 }
1.220     brouard  7062:                                                                
1.222     brouard  7063:                 /* Eigen vectors */
1.280     brouard  7064:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   7065:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   7066:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   7067:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   7068:                 }else
                   7069:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  7070:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   7071:                 v21=(lc1-v1)/cv12*v11;
                   7072:                 v12=-v21;
                   7073:                 v22=v11;
                   7074:                 tnalp=v21/v11;
                   7075:                 if(first1==1){
                   7076:                   first1=0;
                   7077:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   7078:                 }
                   7079:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   7080:                 /*printf(fignu*/
                   7081:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   7082:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   7083:                 if(first==1){
                   7084:                   first=0;
                   7085:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   7086:                   fprintf(ficgp,"\nset parametric;unset label");
                   7087:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   7088:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  7089:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  7090:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  7091: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  7092:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   7093:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7094:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7095:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   7096:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7097:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   7098:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   7099:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  7100:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   7101:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  7102:                 }else{
                   7103:                   first=0;
                   7104:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   7105:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   7106:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   7107:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  7108:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   7109:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  7110:                 }/* if first */
                   7111:               } /* age mod 5 */
                   7112:             } /* end loop age */
                   7113:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7114:             first=1;
                   7115:           } /*l12 */
                   7116:         } /* k12 */
                   7117:        } /*l1 */
                   7118:      }/* k1 */
                   7119:    }  /* loop on combination of covariates j1 */
                   7120:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   7121:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   7122:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   7123:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   7124:    free_vector(xp,1,npar);
                   7125:    fclose(ficresprob);
                   7126:    fclose(ficresprobcov);
                   7127:    fclose(ficresprobcor);
                   7128:    fflush(ficgp);
                   7129:    fflush(fichtmcov);
                   7130:  }
1.126     brouard  7131: 
                   7132: 
                   7133: /******************* Printing html file ***********/
1.201     brouard  7134: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  7135:                  int lastpass, int stepm, int weightopt, char model[],\
                   7136:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.296     brouard  7137:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int prevbcast, int estepm , \
                   7138:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateprojd, double dateback1, \
                   7139:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateprojf, double dateback2){
1.237     brouard  7140:   int jj1, k1, i1, cpt, k4, nres;
1.319     brouard  7141:   /* In fact some results are already printed in fichtm which is open */
1.126     brouard  7142:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   7143:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   7144: </ul>");
1.319     brouard  7145: /*    fprintf(fichtm,"<ul><li> model=1+age+%s\n \ */
                   7146: /* </ul>", model); */
1.214     brouard  7147:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   7148:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   7149:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   7150:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  7151:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   7152:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  7153:    fprintf(fichtm,"\
                   7154:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  7155:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  7156:    fprintf(fichtm,"\
1.217     brouard  7157:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   7158:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   7159:    fprintf(fichtm,"\
1.288     brouard  7160:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  7161:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  7162:    fprintf(fichtm,"\
1.288     brouard  7163:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  7164:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   7165:    fprintf(fichtm,"\
1.211     brouard  7166:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  7167:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  7168:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  7169:    if(prevfcast==1){
                   7170:      fprintf(fichtm,"\
                   7171:  - Prevalence projections by age and states:                           \
1.201     brouard  7172:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  7173:    }
1.126     brouard  7174: 
                   7175: 
1.225     brouard  7176:    m=pow(2,cptcoveff);
1.222     brouard  7177:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7178: 
1.317     brouard  7179:    fprintf(fichtm," \n<ul><li><b>Graphs (first order)</b></li><p>");
1.264     brouard  7180: 
                   7181:    jj1=0;
                   7182: 
                   7183:    fprintf(fichtm," \n<ul>");
                   7184:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7185:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   7186:      if(m != 1 && TKresult[nres]!= k1)
                   7187:        continue;
                   7188:      jj1++;
                   7189:      if (cptcovn > 0) {
                   7190:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   7191:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7192:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7193:        }
                   7194:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7195:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7196:        }
                   7197:        fprintf(fichtm,"\">");
                   7198:        
                   7199:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   7200:        fprintf(fichtm,"************ Results for covariates");
                   7201:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7202:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7203:        }
                   7204:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7205:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7206:        }
                   7207:        if(invalidvarcomb[k1]){
                   7208:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   7209:         continue;
                   7210:        }
                   7211:        fprintf(fichtm,"</a></li>");
                   7212:      } /* cptcovn >0 */
                   7213:    }
1.317     brouard  7214:    fprintf(fichtm," \n</ul>");
1.264     brouard  7215: 
1.222     brouard  7216:    jj1=0;
1.237     brouard  7217: 
                   7218:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  7219:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  7220:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7221:        continue;
1.220     brouard  7222: 
1.222     brouard  7223:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7224:      jj1++;
                   7225:      if (cptcovn > 0) {
1.264     brouard  7226:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   7227:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7228:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7229:        }
                   7230:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7231:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7232:        }
                   7233:        fprintf(fichtm,"\"</a>");
                   7234:  
1.222     brouard  7235:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7236:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  7237:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7238:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   7239:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7240:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  7241:        }
1.237     brouard  7242:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7243:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7244:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   7245:       }
                   7246:        
1.230     brouard  7247:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.321     brouard  7248:        fprintf(fichtm," (model=%s) ************\n<hr size=\"2\" color=\"#EC5E5E\">",model);
1.222     brouard  7249:        if(invalidvarcomb[k1]){
                   7250:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   7251:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   7252:         continue;
                   7253:        }
                   7254:      }
                   7255:      /* aij, bij */
1.259     brouard  7256:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  7257: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  7258:      /* Pij */
1.241     brouard  7259:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   7260: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  7261:      /* Quasi-incidences */
                   7262:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  7263:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  7264:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  7265: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   7266: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  7267:      /* Survival functions (period) in state j */
                   7268:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7269:        fprintf(fichtm,"<br>\n- Survival functions in state %d. And probability to be observed in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7270: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  7271:      }
                   7272:      /* State specific survival functions (period) */
                   7273:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7274:        fprintf(fichtm,"<br>\n- Survival functions in state %d and in any other live state (total).\
                   7275:  And probability to be observed in various states (up to %d) being in state %d at different ages.      \
1.283     brouard  7276:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  7277:      }
1.288     brouard  7278:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  7279:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7280:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7281: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  7282:      }
1.296     brouard  7283:      if(prevbcast==1){
1.288     brouard  7284:        /* Backward prevalence in each health state */
1.222     brouard  7285:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7286:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7287: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  7288:        }
1.217     brouard  7289:      }
1.222     brouard  7290:      if(prevfcast==1){
1.288     brouard  7291:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  7292:        for(cpt=1; cpt<=nlstate;cpt++){
1.314     brouard  7293:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>", dateprev1, dateprev2, mobilavproj, dateprojd, dateprojf, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
                   7294:         fprintf(fichtm," (data from text file  <a href=\"%s.txt\">%s.txt</a>)\n<br>",subdirf2(optionfilefiname,"F_"),subdirf2(optionfilefiname,"F_"));
                   7295:         fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">",
                   7296:                 subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  7297:        }
                   7298:      }
1.296     brouard  7299:      if(prevbcast==1){
1.268     brouard  7300:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   7301:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  7302:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   7303:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   7304:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
1.314     brouard  7305: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7306:         fprintf(fichtm," (data from text file  <a href=\"%s.txt\">%s.txt</a>)\n<br>",subdirf2(optionfilefiname,"FB_"),subdirf2(optionfilefiname,"FB_"));
                   7307:         fprintf(fichtm," <img src=\"%s_%d-%d-%d.svg\">", subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  7308:        }
                   7309:      }
1.220     brouard  7310:         
1.222     brouard  7311:      for(cpt=1; cpt<=nlstate;cpt++) {
1.314     brouard  7312:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
                   7313:        fprintf(fichtm," (data from text file  <a href=\"%s.txt\"> %s.txt</a>)\n<br>",subdirf2(optionfilefiname,"E_"),subdirf2(optionfilefiname,"E_"));
                   7314:        fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">", subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres );
1.222     brouard  7315:      }
                   7316:      /* } /\* end i1 *\/ */
                   7317:    }/* End k1 */
                   7318:    fprintf(fichtm,"</ul>");
1.126     brouard  7319: 
1.222     brouard  7320:    fprintf(fichtm,"\
1.126     brouard  7321: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  7322:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  7323:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  7324: But because parameters are usually highly correlated (a higher incidence of disability \
                   7325: and a higher incidence of recovery can give very close observed transition) it might \
                   7326: be very useful to look not only at linear confidence intervals estimated from the \
                   7327: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   7328: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   7329: covariance matrix of the one-step probabilities. \
                   7330: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  7331: 
1.222     brouard  7332:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   7333:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   7334:    fprintf(fichtm,"\
1.126     brouard  7335:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7336:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  7337: 
1.222     brouard  7338:    fprintf(fichtm,"\
1.126     brouard  7339:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7340:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   7341:    fprintf(fichtm,"\
1.126     brouard  7342:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7343:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7344:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7345:    fprintf(fichtm,"\
1.126     brouard  7346:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7347:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7348:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7349:    fprintf(fichtm,"\
1.288     brouard  7350:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7351:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7352:    fprintf(fichtm,"\
1.128     brouard  7353:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7354:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7355:    fprintf(fichtm,"\
1.288     brouard  7356:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7357:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7358: 
                   7359: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7360: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7361: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7362: /*     <br>",fileres,fileres,fileres,fileres); */
                   7363: /*  else  */
                   7364: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7365:    fflush(fichtm);
1.126     brouard  7366: 
1.225     brouard  7367:    m=pow(2,cptcoveff);
1.222     brouard  7368:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7369: 
1.317     brouard  7370:    fprintf(fichtm," <ul><li><b>Graphs (second order)</b></li><p>");
                   7371: 
                   7372:   jj1=0;
                   7373: 
                   7374:    fprintf(fichtm," \n<ul>");
                   7375:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7376:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   7377:      if(m != 1 && TKresult[nres]!= k1)
                   7378:        continue;
                   7379:      jj1++;
                   7380:      if (cptcovn > 0) {
                   7381:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescovsecond");
                   7382:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7383:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7384:        }
                   7385:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7386:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7387:        }
                   7388:        fprintf(fichtm,"\">");
                   7389:        
                   7390:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   7391:        fprintf(fichtm,"************ Results for covariates");
                   7392:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7393:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7394:        }
                   7395:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7396:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7397:        }
                   7398:        if(invalidvarcomb[k1]){
                   7399:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   7400:         continue;
                   7401:        }
                   7402:        fprintf(fichtm,"</a></li>");
                   7403:      } /* cptcovn >0 */
                   7404:    }
                   7405:    fprintf(fichtm," \n</ul>");
                   7406: 
1.222     brouard  7407:    jj1=0;
1.237     brouard  7408: 
1.241     brouard  7409:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7410:    for(k1=1; k1<=m;k1++){
1.253     brouard  7411:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7412:        continue;
1.222     brouard  7413:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7414:      jj1++;
1.126     brouard  7415:      if (cptcovn > 0) {
1.317     brouard  7416:        fprintf(fichtm,"\n<p><a name=\"rescovsecond");
                   7417:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7418:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7419:        }
                   7420:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7421:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7422:        }
                   7423:        fprintf(fichtm,"\"</a>");
                   7424:        
1.126     brouard  7425:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.317     brouard  7426:        for (cpt=1; cpt<=cptcoveff;cpt++){  /**< cptcoveff number of variables */
1.237     brouard  7427:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
1.317     brouard  7428:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
1.237     brouard  7429:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
1.317     brouard  7430:        }
1.237     brouard  7431:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7432:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7433:       }
                   7434: 
1.321     brouard  7435:        fprintf(fichtm," (model=%s) ************\n<hr size=\"2\" color=\"#EC5E5E\">",model);
1.220     brouard  7436: 
1.222     brouard  7437:        if(invalidvarcomb[k1]){
                   7438:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7439:         continue;
                   7440:        }
1.126     brouard  7441:      }
                   7442:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7443:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.314     brouard  7444: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7445:        fprintf(fichtm," (data from text file  <a href=\"%s\">%s</a>)\n <br>",subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
                   7446:        fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">",subdirf2(optionfilefiname,"V_"), cpt,k1,nres);
1.126     brouard  7447:      }
                   7448:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.314     brouard  7449: health expectancies in each live states (1 to %d). If popbased=1 the smooth (due to the model) \
1.128     brouard  7450: true period expectancies (those weighted with period prevalences are also\
                   7451:  drawn in addition to the population based expectancies computed using\
1.314     brouard  7452:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>",nlstate, subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
                   7453:      fprintf(fichtm," (data from text file <a href=\"%s.txt\">%s.txt</a>) \n<br>",subdirf2(optionfilefiname,"T_"),subdirf2(optionfilefiname,"T_"));
                   7454:      fprintf(fichtm,"<img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7455:      /* } /\* end i1 *\/ */
                   7456:    }/* End k1 */
1.241     brouard  7457:   }/* End nres */
1.222     brouard  7458:    fprintf(fichtm,"</ul>");
                   7459:    fflush(fichtm);
1.126     brouard  7460: }
                   7461: 
                   7462: /******************* Gnuplot file **************/
1.296     brouard  7463: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int prevbcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7464: 
                   7465:   char dirfileres[132],optfileres[132];
1.264     brouard  7466:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7467:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7468:   int lv=0, vlv=0, kl=0;
1.130     brouard  7469:   int ng=0;
1.201     brouard  7470:   int vpopbased;
1.223     brouard  7471:   int ioffset; /* variable offset for columns */
1.270     brouard  7472:   int iyearc=1; /* variable column for year of projection  */
                   7473:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7474:   int nres=0; /* Index of resultline */
1.266     brouard  7475:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7476: 
1.126     brouard  7477: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7478: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7479: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7480: /*   } */
                   7481: 
                   7482:   /*#ifdef windows */
                   7483:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7484:   /*#endif */
1.225     brouard  7485:   m=pow(2,cptcoveff);
1.126     brouard  7486: 
1.274     brouard  7487:   /* diagram of the model */
                   7488:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7489:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7490:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7491:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7492: 
                   7493:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7494:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7495:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7496:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7497:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7498:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7499:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7500: 
1.202     brouard  7501:   /* Contribution to likelihood */
                   7502:   /* Plot the probability implied in the likelihood */
1.223     brouard  7503:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7504:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7505:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7506:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7507: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7508:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7509: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7510:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7511:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7512:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7513:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7514:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7515:   for (i=1; i<= nlstate ; i ++) {
                   7516:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7517:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7518:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7519:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7520:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7521:     }
                   7522:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7523:   }
                   7524:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7525:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7526:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7527:   fprintf(ficgp,"\nset out;unset log\n");
                   7528:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7529: 
1.126     brouard  7530:   strcpy(dirfileres,optionfilefiname);
                   7531:   strcpy(optfileres,"vpl");
1.223     brouard  7532:   /* 1eme*/
1.238     brouard  7533:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7534:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7535:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7536:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7537:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7538:          continue;
                   7539:        /* We are interested in selected combination by the resultline */
1.246     brouard  7540:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7541:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7542:        strcpy(gplotlabel,"(");
1.238     brouard  7543:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7544:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7545:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7546:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7547:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7548:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7549:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7550:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7551:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7552:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7553:        }
                   7554:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7555:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7556:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7557:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7558:        }
                   7559:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7560:        /* printf("\n#\n"); */
1.238     brouard  7561:        fprintf(ficgp,"\n#\n");
                   7562:        if(invalidvarcomb[k1]){
1.260     brouard  7563:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7564:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7565:          continue;
                   7566:        }
1.235     brouard  7567:       
1.241     brouard  7568:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7569:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7570:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
1.321     brouard  7571:        fprintf(ficgp,"set title \"Alive state %d %s model=%s\" font \"Helvetica,12\"\n",cpt,gplotlabel,model);
1.260     brouard  7572:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7573:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7574:       /* k1-1 error should be nres-1*/
1.238     brouard  7575:        for (i=1; i<= nlstate ; i ++) {
                   7576:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7577:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7578:        }
1.288     brouard  7579:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7580:        for (i=1; i<= nlstate ; i ++) {
                   7581:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7582:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7583:        } 
1.260     brouard  7584:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7585:        for (i=1; i<= nlstate ; i ++) {
                   7586:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7587:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7588:        }  
1.265     brouard  7589:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7590:        
                   7591:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7592:         if(cptcoveff ==0){
1.271     brouard  7593:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7594:        }else{
                   7595:          kl=0;
                   7596:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7597:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7598:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7599:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7600:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7601:            vlv= nbcode[Tvaraff[k]][lv];
                   7602:            kl++;
                   7603:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7604:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7605:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7606:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7607:            if(k==cptcoveff){
                   7608:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7609:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7610:            }else{
                   7611:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7612:              kl++;
                   7613:            }
                   7614:          } /* end covariate */
                   7615:        } /* end if no covariate */
                   7616: 
1.296     brouard  7617:        if(prevbcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
1.238     brouard  7618:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7619:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7620:          if(cptcoveff ==0){
1.245     brouard  7621:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7622:          }else{
                   7623:            kl=0;
                   7624:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7625:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7626:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7627:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7628:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7629:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7630:              kl++;
1.238     brouard  7631:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7632:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7633:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7634:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7635:              if(k==cptcoveff){
1.245     brouard  7636:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7637:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7638:              }else{
                   7639:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7640:                kl++;
                   7641:              }
                   7642:            } /* end covariate */
                   7643:          } /* end if no covariate */
1.296     brouard  7644:          if(prevbcast == 1){
1.268     brouard  7645:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7646:            /* k1-1 error should be nres-1*/
                   7647:            for (i=1; i<= nlstate ; i ++) {
                   7648:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7649:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7650:            }
1.271     brouard  7651:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7652:            for (i=1; i<= nlstate ; i ++) {
                   7653:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7654:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7655:            } 
1.276     brouard  7656:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7657:            for (i=1; i<= nlstate ; i ++) {
                   7658:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7659:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7660:            } 
1.274     brouard  7661:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7662:          } /* end if backprojcast */
1.296     brouard  7663:        } /* end if prevbcast */
1.276     brouard  7664:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7665:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7666:       } /* nres */
1.201     brouard  7667:     } /* k1 */
                   7668:   } /* cpt */
1.235     brouard  7669: 
                   7670:   
1.126     brouard  7671:   /*2 eme*/
1.238     brouard  7672:   for (k1=1; k1<= m ; k1 ++){  
                   7673:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7674:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7675:        continue;
                   7676:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7677:       strcpy(gplotlabel,"(");
1.238     brouard  7678:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7679:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7680:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7681:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7682:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7683:        vlv= nbcode[Tvaraff[k]][lv];
                   7684:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7685:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7686:       }
1.237     brouard  7687:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7688:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7689:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7690:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7691:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7692:       }
1.264     brouard  7693:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7694:       fprintf(ficgp,"\n#\n");
1.223     brouard  7695:       if(invalidvarcomb[k1]){
                   7696:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7697:        continue;
                   7698:       }
1.219     brouard  7699:                        
1.241     brouard  7700:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7701:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7702:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7703:        if(vpopbased==0){
1.238     brouard  7704:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7705:        }else
1.238     brouard  7706:          fprintf(ficgp,"\nreplot ");
                   7707:        for (i=1; i<= nlstate+1 ; i ++) {
                   7708:          k=2*i;
1.261     brouard  7709:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7710:          for (j=1; j<= nlstate+1 ; j ++) {
                   7711:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7712:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7713:          }   
                   7714:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7715:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7716:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7717:          for (j=1; j<= nlstate+1 ; j ++) {
                   7718:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7719:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7720:          }   
                   7721:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7722:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7723:          for (j=1; j<= nlstate+1 ; j ++) {
                   7724:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7725:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7726:          }   
                   7727:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7728:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7729:        } /* state */
                   7730:       } /* vpopbased */
1.264     brouard  7731:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7732:     } /* end nres */
                   7733:   } /* k1 end 2 eme*/
                   7734:        
                   7735:        
                   7736:   /*3eme*/
                   7737:   for (k1=1; k1<= m ; k1 ++){
                   7738:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7739:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7740:        continue;
                   7741: 
                   7742:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7743:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7744:        strcpy(gplotlabel,"(");
1.238     brouard  7745:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7746:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7747:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7748:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7749:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7750:          vlv= nbcode[Tvaraff[k]][lv];
                   7751:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7752:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7753:        }
                   7754:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7755:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7756:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7757:        }       
1.264     brouard  7758:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7759:        fprintf(ficgp,"\n#\n");
                   7760:        if(invalidvarcomb[k1]){
                   7761:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7762:          continue;
                   7763:        }
                   7764:                        
                   7765:        /*       k=2+nlstate*(2*cpt-2); */
                   7766:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7767:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7768:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7769:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7770: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7771:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7772:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7773:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7774:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7775:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7776:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7777:                                
1.238     brouard  7778:        */
                   7779:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7780:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7781:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7782:                                
1.238     brouard  7783:        } 
1.261     brouard  7784:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7785:       }
1.264     brouard  7786:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7787:     } /* end nres */
                   7788:   } /* end kl 3eme */
1.126     brouard  7789:   
1.223     brouard  7790:   /* 4eme */
1.201     brouard  7791:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7792:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7793:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7794:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7795:        continue;
1.238     brouard  7796:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7797:        strcpy(gplotlabel,"(");
1.238     brouard  7798:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7799:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7800:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7801:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7802:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7803:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7804:          vlv= nbcode[Tvaraff[k]][lv];
                   7805:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7806:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7807:        }
                   7808:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7809:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7810:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7811:        }       
1.264     brouard  7812:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7813:        fprintf(ficgp,"\n#\n");
                   7814:        if(invalidvarcomb[k1]){
                   7815:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7816:          continue;
1.223     brouard  7817:        }
1.238     brouard  7818:       
1.241     brouard  7819:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7820:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7821:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7822: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7823:        k=3;
                   7824:        for (i=1; i<= nlstate ; i ++){
                   7825:          if(i==1){
                   7826:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7827:          }else{
                   7828:            fprintf(ficgp,", '' ");
                   7829:          }
                   7830:          l=(nlstate+ndeath)*(i-1)+1;
                   7831:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7832:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7833:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7834:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7835:        } /* nlstate */
1.264     brouard  7836:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7837:       } /* end cpt state*/ 
                   7838:     } /* end nres */
                   7839:   } /* end covariate k1 */  
                   7840: 
1.220     brouard  7841: /* 5eme */
1.201     brouard  7842:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7843:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7844:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7845:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7846:        continue;
1.238     brouard  7847:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7848:        strcpy(gplotlabel,"(");
1.238     brouard  7849:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7850:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7851:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7852:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7853:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7854:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7855:          vlv= nbcode[Tvaraff[k]][lv];
                   7856:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7857:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7858:        }
                   7859:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7860:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7861:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7862:        }       
1.264     brouard  7863:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7864:        fprintf(ficgp,"\n#\n");
                   7865:        if(invalidvarcomb[k1]){
                   7866:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7867:          continue;
                   7868:        }
1.227     brouard  7869:       
1.241     brouard  7870:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7871:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7872:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7873: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7874:        k=3;
                   7875:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7876:          if(j==1)
                   7877:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7878:          else
                   7879:            fprintf(ficgp,", '' ");
                   7880:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7881:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7882:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7883:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7884:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7885:        } /* nlstate */
                   7886:        fprintf(ficgp,", '' ");
                   7887:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7888:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7889:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7890:          if(j < nlstate)
                   7891:            fprintf(ficgp,"$%d +",k+l);
                   7892:          else
                   7893:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7894:        }
1.264     brouard  7895:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7896:       } /* end cpt state*/ 
                   7897:     } /* end covariate */  
                   7898:   } /* end nres */
1.227     brouard  7899:   
1.220     brouard  7900: /* 6eme */
1.202     brouard  7901:   /* CV preval stable (period) for each covariate */
1.237     brouard  7902:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7903:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7904:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7905:       continue;
1.255     brouard  7906:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7907:       strcpy(gplotlabel,"(");      
1.288     brouard  7908:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7909:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7910:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7911:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7912:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7913:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7914:        vlv= nbcode[Tvaraff[k]][lv];
                   7915:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7916:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7917:       }
1.237     brouard  7918:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7919:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7920:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7921:       }        
1.264     brouard  7922:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7923:       fprintf(ficgp,"\n#\n");
1.223     brouard  7924:       if(invalidvarcomb[k1]){
1.227     brouard  7925:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7926:        continue;
1.223     brouard  7927:       }
1.227     brouard  7928:       
1.241     brouard  7929:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7930:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7931:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7932: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7933:       k=3; /* Offset */
1.255     brouard  7934:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7935:        if(i==1)
                   7936:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7937:        else
                   7938:          fprintf(ficgp,", '' ");
1.255     brouard  7939:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7940:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7941:        for (j=2; j<= nlstate ; j ++)
                   7942:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7943:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7944:       } /* nlstate */
1.264     brouard  7945:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7946:     } /* end cpt state*/ 
                   7947:   } /* end covariate */  
1.227     brouard  7948:   
                   7949:   
1.220     brouard  7950: /* 7eme */
1.296     brouard  7951:   if(prevbcast == 1){
1.288     brouard  7952:     /* CV backward prevalence  for each covariate */
1.237     brouard  7953:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7954:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7955:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7956:        continue;
1.268     brouard  7957:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7958:        strcpy(gplotlabel,"(");      
1.288     brouard  7959:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7960:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7961:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7962:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7963:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7964:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7965:          vlv= nbcode[Tvaraff[k]][lv];
                   7966:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7967:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7968:        }
1.237     brouard  7969:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7970:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7971:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7972:        }       
1.264     brouard  7973:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7974:        fprintf(ficgp,"\n#\n");
                   7975:        if(invalidvarcomb[k1]){
                   7976:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7977:          continue;
                   7978:        }
                   7979:        
1.241     brouard  7980:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7981:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7982:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7983: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7984:        k=3; /* Offset */
1.268     brouard  7985:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7986:          if(i==1)
                   7987:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7988:          else
                   7989:            fprintf(ficgp,", '' ");
                   7990:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7991:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7992:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7993:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7994:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7995:          /* for (j=2; j<= nlstate ; j ++) */
                   7996:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7997:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7998:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7999:        } /* nlstate */
1.264     brouard  8000:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  8001:       } /* end cpt state*/ 
                   8002:     } /* end covariate */  
1.296     brouard  8003:   } /* End if prevbcast */
1.218     brouard  8004:   
1.223     brouard  8005:   /* 8eme */
1.218     brouard  8006:   if(prevfcast==1){
1.288     brouard  8007:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  8008:     
1.237     brouard  8009:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   8010:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  8011:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  8012:        continue;
1.211     brouard  8013:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  8014:        strcpy(gplotlabel,"(");      
1.288     brouard  8015:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  8016:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8017:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8018:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8019:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8020:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8021:          vlv= nbcode[Tvaraff[k]][lv];
                   8022:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  8023:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  8024:        }
1.237     brouard  8025:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8026:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  8027:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  8028:        }       
1.264     brouard  8029:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  8030:        fprintf(ficgp,"\n#\n");
                   8031:        if(invalidvarcomb[k1]){
                   8032:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   8033:          continue;
                   8034:        }
                   8035:        
                   8036:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  8037:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  8038:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  8039:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  8040: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  8041: 
                   8042:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   8043:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8044:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8045:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  8046:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8047:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   8048:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8049:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  8050:          if(i==istart){
1.227     brouard  8051:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   8052:          }else{
                   8053:            fprintf(ficgp,",\\\n '' ");
                   8054:          }
                   8055:          if(cptcoveff ==0){ /* No covariate */
                   8056:            ioffset=2; /* Age is in 2 */
                   8057:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8058:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8059:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8060:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8061:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  8062:            if(i==nlstate+1){
1.270     brouard  8063:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  8064:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   8065:              fprintf(ficgp,",\\\n '' ");
                   8066:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  8067:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  8068:                     offyear,                           \
1.268     brouard  8069:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  8070:            }else
1.227     brouard  8071:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   8072:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   8073:          }else{ /* more than 2 covariates */
1.270     brouard  8074:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   8075:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8076:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   8077:            iyearc=ioffset-1;
                   8078:            iagec=ioffset;
1.227     brouard  8079:            fprintf(ficgp," u %d:(",ioffset); 
                   8080:            kl=0;
                   8081:            strcpy(gplotcondition,"(");
                   8082:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   8083:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   8084:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8085:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8086:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8087:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   8088:              kl++;
                   8089:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   8090:              kl++;
                   8091:              if(k <cptcoveff && cptcoveff>1)
                   8092:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   8093:            }
                   8094:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   8095:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   8096:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   8097:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   8098:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   8099:            if(i==nlstate+1){
1.270     brouard  8100:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   8101:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  8102:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  8103:              fprintf(ficgp," u %d:(",iagec); 
                   8104:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   8105:                      iyearc, iagec, offyear,                           \
                   8106:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  8107: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  8108:            }else{
                   8109:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   8110:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   8111:            }
                   8112:          } /* end if covariate */
                   8113:        } /* nlstate */
1.264     brouard  8114:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  8115:       } /* end cpt state*/
                   8116:     } /* end covariate */
                   8117:   } /* End if prevfcast */
1.227     brouard  8118:   
1.296     brouard  8119:   if(prevbcast==1){
1.268     brouard  8120:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   8121:     
                   8122:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   8123:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   8124:       if(m != 1 && TKresult[nres]!= k1)
                   8125:        continue;
                   8126:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   8127:        strcpy(gplotlabel,"(");      
                   8128:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   8129:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8130:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8131:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8132:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8133:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8134:          vlv= nbcode[Tvaraff[k]][lv];
                   8135:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   8136:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   8137:        }
                   8138:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8139:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8140:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8141:        }       
                   8142:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   8143:        fprintf(ficgp,"\n#\n");
                   8144:        if(invalidvarcomb[k1]){
                   8145:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   8146:          continue;
                   8147:        }
                   8148:        
                   8149:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   8150:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   8151:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   8152:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   8153: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   8154: 
                   8155:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   8156:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8157:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8158:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   8159:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8160:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   8161:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8162:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   8163:          if(i==istart){
                   8164:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   8165:          }else{
                   8166:            fprintf(ficgp,",\\\n '' ");
                   8167:          }
                   8168:          if(cptcoveff ==0){ /* No covariate */
                   8169:            ioffset=2; /* Age is in 2 */
                   8170:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8171:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8172:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8173:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8174:            fprintf(ficgp," u %d:(", ioffset); 
                   8175:            if(i==nlstate+1){
1.270     brouard  8176:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  8177:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   8178:              fprintf(ficgp,",\\\n '' ");
                   8179:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  8180:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  8181:                     offbyear,                          \
                   8182:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   8183:            }else
                   8184:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   8185:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   8186:          }else{ /* more than 2 covariates */
1.270     brouard  8187:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   8188:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8189:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   8190:            iyearc=ioffset-1;
                   8191:            iagec=ioffset;
1.268     brouard  8192:            fprintf(ficgp," u %d:(",ioffset); 
                   8193:            kl=0;
                   8194:            strcpy(gplotcondition,"(");
                   8195:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   8196:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   8197:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8198:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8199:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8200:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   8201:              kl++;
                   8202:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   8203:              kl++;
                   8204:              if(k <cptcoveff && cptcoveff>1)
                   8205:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   8206:            }
                   8207:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   8208:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   8209:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   8210:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   8211:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   8212:            if(i==nlstate+1){
1.270     brouard  8213:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   8214:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  8215:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  8216:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  8217:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  8218:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   8219:                      iyearc,iagec,offbyear,                            \
                   8220:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  8221: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   8222:            }else{
                   8223:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   8224:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   8225:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   8226:            }
                   8227:          } /* end if covariate */
                   8228:        } /* nlstate */
                   8229:        fprintf(ficgp,"\nset out; unset label;\n");
                   8230:       } /* end cpt state*/
                   8231:     } /* end covariate */
1.296     brouard  8232:   } /* End if prevbcast */
1.268     brouard  8233:   
1.227     brouard  8234:   
1.238     brouard  8235:   /* 9eme writing MLE parameters */
                   8236:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  8237:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  8238:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  8239:     for(k=1; k <=(nlstate+ndeath); k++){
                   8240:       if (k != i) {
1.227     brouard  8241:        fprintf(ficgp,"#   current state %d\n",k);
                   8242:        for(j=1; j <=ncovmodel; j++){
                   8243:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   8244:          jk++; 
                   8245:        }
                   8246:        fprintf(ficgp,"\n");
1.126     brouard  8247:       }
                   8248:     }
1.223     brouard  8249:   }
1.187     brouard  8250:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  8251:   
1.145     brouard  8252:   /*goto avoid;*/
1.238     brouard  8253:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   8254:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  8255:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   8256:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   8257:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   8258:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   8259:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8260:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8261:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8262:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8263:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   8264:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8265:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   8266:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   8267:   fprintf(ficgp,"#\n");
1.223     brouard  8268:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  8269:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  8270:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  8271:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  8272:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   8273:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  8274:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  8275:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  8276:        continue;
1.264     brouard  8277:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   8278:       strcpy(gplotlabel,"(");
1.276     brouard  8279:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  8280:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8281:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8282:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8283:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8284:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8285:        vlv= nbcode[Tvaraff[k]][lv];
                   8286:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   8287:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   8288:       }
1.237     brouard  8289:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8290:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  8291:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  8292:       }        
1.264     brouard  8293:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  8294:       fprintf(ficgp,"\n#\n");
1.264     brouard  8295:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  8296:       fprintf(ficgp,"\nset key outside ");
                   8297:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   8298:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  8299:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   8300:       if (ng==1){
                   8301:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   8302:        fprintf(ficgp,"\nunset log y");
                   8303:       }else if (ng==2){
                   8304:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   8305:        fprintf(ficgp,"\nset log y");
                   8306:       }else if (ng==3){
                   8307:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   8308:        fprintf(ficgp,"\nset log y");
                   8309:       }else
                   8310:        fprintf(ficgp,"\nunset title ");
                   8311:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   8312:       i=1;
                   8313:       for(k2=1; k2<=nlstate; k2++) {
                   8314:        k3=i;
                   8315:        for(k=1; k<=(nlstate+ndeath); k++) {
                   8316:          if (k != k2){
                   8317:            switch( ng) {
                   8318:            case 1:
                   8319:              if(nagesqr==0)
                   8320:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   8321:              else /* nagesqr =1 */
                   8322:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8323:              break;
                   8324:            case 2: /* ng=2 */
                   8325:              if(nagesqr==0)
                   8326:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   8327:              else /* nagesqr =1 */
                   8328:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8329:              break;
                   8330:            case 3:
                   8331:              if(nagesqr==0)
                   8332:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   8333:              else /* nagesqr =1 */
                   8334:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   8335:              break;
                   8336:            }
                   8337:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  8338:            ijp=1; /* product no age */
                   8339:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   8340:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  8341:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  8342:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8343:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   8344:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8345:                    if(DummyV[j]==0){
                   8346:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   8347:                    }else{ /* quantitative */
                   8348:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   8349:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8350:                    }
                   8351:                    ij++;
1.237     brouard  8352:                  }
1.268     brouard  8353:                } 
                   8354:              }else if(cptcovprod >0){
                   8355:                if(j==Tprod[ijp]) { /* */ 
                   8356:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   8357:                  if(ijp <=cptcovprod) { /* Product */
                   8358:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   8359:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   8360:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   8361:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   8362:                      }else{ /* Vn is dummy and Vm is quanti */
                   8363:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   8364:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8365:                      }
                   8366:                    }else{ /* Vn*Vm Vn is quanti */
                   8367:                      if(DummyV[Tvard[ijp][2]]==0){
                   8368:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   8369:                      }else{ /* Both quanti */
                   8370:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8371:                      }
1.237     brouard  8372:                    }
1.268     brouard  8373:                    ijp++;
1.237     brouard  8374:                  }
1.268     brouard  8375:                } /* end Tprod */
1.237     brouard  8376:              } else{  /* simple covariate */
1.264     brouard  8377:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  8378:                if(Dummy[j]==0){
                   8379:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   8380:                }else{ /* quantitative */
                   8381:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  8382:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  8383:                }
1.237     brouard  8384:              } /* end simple */
                   8385:            } /* end j */
1.223     brouard  8386:          }else{
                   8387:            i=i-ncovmodel;
                   8388:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   8389:              fprintf(ficgp," (1.");
                   8390:          }
1.227     brouard  8391:          
1.223     brouard  8392:          if(ng != 1){
                   8393:            fprintf(ficgp,")/(1");
1.227     brouard  8394:            
1.264     brouard  8395:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8396:              if(nagesqr==0)
1.264     brouard  8397:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8398:              else /* nagesqr =1 */
1.264     brouard  8399:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8400:               
1.223     brouard  8401:              ij=1;
                   8402:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8403:                 if(cptcovage >0){ 
                   8404:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8405:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8406:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8407:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8408:                       ij++;
                   8409:                     }
                   8410:                   }
                   8411:                 }else
                   8412:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8413:              }
                   8414:              fprintf(ficgp,")");
                   8415:            }
                   8416:            fprintf(ficgp,")");
                   8417:            if(ng ==2)
1.276     brouard  8418:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8419:            else /* ng= 3 */
1.276     brouard  8420:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8421:          }else{ /* end ng <> 1 */
                   8422:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8423:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8424:          }
                   8425:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8426:            fprintf(ficgp,",");
                   8427:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8428:            fprintf(ficgp,",");
                   8429:          i=i+ncovmodel;
                   8430:        } /* end k */
                   8431:       } /* end k2 */
1.276     brouard  8432:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8433:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8434:     } /* end k1 */
1.223     brouard  8435:   } /* end ng */
                   8436:   /* avoid: */
                   8437:   fflush(ficgp); 
1.126     brouard  8438: }  /* end gnuplot */
                   8439: 
                   8440: 
                   8441: /*************** Moving average **************/
1.219     brouard  8442: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8443:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8444:    
1.222     brouard  8445:    int i, cpt, cptcod;
                   8446:    int modcovmax =1;
                   8447:    int mobilavrange, mob;
                   8448:    int iage=0;
1.288     brouard  8449:    int firstA1=0, firstA2=0;
1.222     brouard  8450: 
1.266     brouard  8451:    double sum=0., sumr=0.;
1.222     brouard  8452:    double age;
1.266     brouard  8453:    double *sumnewp, *sumnewm, *sumnewmr;
                   8454:    double *agemingood, *agemaxgood; 
                   8455:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8456:   
                   8457:   
1.278     brouard  8458:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8459:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8460: 
                   8461:    sumnewp = vector(1,ncovcombmax);
                   8462:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8463:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8464:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8465:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8466:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8467:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8468: 
                   8469:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8470:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8471:      sumnewp[cptcod]=0.;
1.266     brouard  8472:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8473:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8474:    }
                   8475:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8476:   
1.266     brouard  8477:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8478:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8479:      else mobilavrange=mobilav;
                   8480:      for (age=bage; age<=fage; age++)
                   8481:        for (i=1; i<=nlstate;i++)
                   8482:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8483:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8484:      /* We keep the original values on the extreme ages bage, fage and for 
                   8485:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8486:        we use a 5 terms etc. until the borders are no more concerned. 
                   8487:      */ 
                   8488:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8489:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8490:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8491:           sumnewm[cptcod]=0.;
                   8492:           for (i=1; i<=nlstate;i++){
1.222     brouard  8493:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8494:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8495:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8496:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8497:             }
                   8498:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8499:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8500:           } /* end i */
                   8501:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8502:         } /* end cptcod */
1.222     brouard  8503:        }/* end age */
                   8504:      }/* end mob */
1.266     brouard  8505:    }else{
                   8506:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8507:      return -1;
1.266     brouard  8508:    }
                   8509: 
                   8510:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8511:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8512:      if(invalidvarcomb[cptcod]){
                   8513:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8514:        continue;
                   8515:      }
1.219     brouard  8516: 
1.266     brouard  8517:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8518:        sumnewm[cptcod]=0.;
                   8519:        sumnewmr[cptcod]=0.;
                   8520:        for (i=1; i<=nlstate;i++){
                   8521:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8522:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8523:        }
                   8524:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8525:         agemingoodr[cptcod]=age;
                   8526:        }
                   8527:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8528:           agemingood[cptcod]=age;
                   8529:        }
                   8530:      } /* age */
                   8531:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8532:        sumnewm[cptcod]=0.;
1.266     brouard  8533:        sumnewmr[cptcod]=0.;
1.222     brouard  8534:        for (i=1; i<=nlstate;i++){
                   8535:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8536:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8537:        }
                   8538:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8539:         agemaxgoodr[cptcod]=age;
1.222     brouard  8540:        }
                   8541:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8542:         agemaxgood[cptcod]=age;
                   8543:        }
                   8544:      } /* age */
                   8545:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8546:      /* but they will change */
1.288     brouard  8547:      firstA1=0;firstA2=0;
1.266     brouard  8548:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8549:        sumnewm[cptcod]=0.;
                   8550:        sumnewmr[cptcod]=0.;
                   8551:        for (i=1; i<=nlstate;i++){
                   8552:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8553:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8554:        }
                   8555:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8556:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8557:           agemaxgoodr[cptcod]=age;  /* age min */
                   8558:           for (i=1; i<=nlstate;i++)
                   8559:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8560:         }else{ /* bad we change the value with the values of good ages */
                   8561:           for (i=1; i<=nlstate;i++){
                   8562:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8563:           } /* i */
                   8564:         } /* end bad */
                   8565:        }else{
                   8566:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8567:           agemaxgood[cptcod]=age;
                   8568:         }else{ /* bad we change the value with the values of good ages */
                   8569:           for (i=1; i<=nlstate;i++){
                   8570:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8571:           } /* i */
                   8572:         } /* end bad */
                   8573:        }/* end else */
                   8574:        sum=0.;sumr=0.;
                   8575:        for (i=1; i<=nlstate;i++){
                   8576:         sum+=mobaverage[(int)age][i][cptcod];
                   8577:         sumr+=probs[(int)age][i][cptcod];
                   8578:        }
                   8579:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8580:         if(!firstA1){
                   8581:           firstA1=1;
                   8582:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8583:         }
                   8584:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8585:        } /* end bad */
                   8586:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8587:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8588:         if(!firstA2){
                   8589:           firstA2=1;
                   8590:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8591:         }
                   8592:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8593:        } /* end bad */
                   8594:      }/* age */
1.266     brouard  8595: 
                   8596:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8597:        sumnewm[cptcod]=0.;
1.266     brouard  8598:        sumnewmr[cptcod]=0.;
1.222     brouard  8599:        for (i=1; i<=nlstate;i++){
                   8600:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8601:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8602:        } 
                   8603:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8604:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8605:           agemingoodr[cptcod]=age;
                   8606:           for (i=1; i<=nlstate;i++)
                   8607:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8608:         }else{ /* bad we change the value with the values of good ages */
                   8609:           for (i=1; i<=nlstate;i++){
                   8610:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8611:           } /* i */
                   8612:         } /* end bad */
                   8613:        }else{
                   8614:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8615:           agemingood[cptcod]=age;
                   8616:         }else{ /* bad */
                   8617:           for (i=1; i<=nlstate;i++){
                   8618:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8619:           } /* i */
                   8620:         } /* end bad */
                   8621:        }/* end else */
                   8622:        sum=0.;sumr=0.;
                   8623:        for (i=1; i<=nlstate;i++){
                   8624:         sum+=mobaverage[(int)age][i][cptcod];
                   8625:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8626:        }
1.266     brouard  8627:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8628:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8629:        } /* end bad */
                   8630:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8631:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8632:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8633:        } /* end bad */
                   8634:      }/* age */
1.266     brouard  8635: 
1.222     brouard  8636:                
                   8637:      for (age=bage; age<=fage; age++){
1.235     brouard  8638:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8639:        sumnewp[cptcod]=0.;
                   8640:        sumnewm[cptcod]=0.;
                   8641:        for (i=1; i<=nlstate;i++){
                   8642:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8643:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8644:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8645:        }
                   8646:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8647:      }
                   8648:      /* printf("\n"); */
                   8649:      /* } */
1.266     brouard  8650: 
1.222     brouard  8651:      /* brutal averaging */
1.266     brouard  8652:      /* for (i=1; i<=nlstate;i++){ */
                   8653:      /*   for (age=1; age<=bage; age++){ */
                   8654:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8655:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8656:      /*   }     */
                   8657:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8658:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8659:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8660:      /*   } */
                   8661:      /* } /\* end i status *\/ */
                   8662:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8663:      /*   for (age=1; age<=AGESUP; age++){ */
                   8664:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8665:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8666:      /*   } */
                   8667:      /* } */
1.222     brouard  8668:    }/* end cptcod */
1.266     brouard  8669:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8670:    free_vector(agemaxgood,1, ncovcombmax);
                   8671:    free_vector(agemingood,1, ncovcombmax);
                   8672:    free_vector(agemingoodr,1, ncovcombmax);
                   8673:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8674:    free_vector(sumnewm,1, ncovcombmax);
                   8675:    free_vector(sumnewp,1, ncovcombmax);
                   8676:    return 0;
                   8677:  }/* End movingaverage */
1.218     brouard  8678:  
1.126     brouard  8679: 
1.296     brouard  8680:  
1.126     brouard  8681: /************** Forecasting ******************/
1.296     brouard  8682: /* void prevforecast(char fileres[], double dateintmean, double anprojd, double mprojd, double jprojd, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anprojf, double p[], int cptcoveff)*/
                   8683: void prevforecast(char fileres[], double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8684:   /* dateintemean, mean date of interviews
                   8685:      dateprojd, year, month, day of starting projection 
                   8686:      dateprojf date of end of projection;year of end of projection (same day and month as proj1).
1.126     brouard  8687:      agemin, agemax range of age
                   8688:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8689:   */
1.296     brouard  8690:   /* double anprojd, mprojd, jprojd; */
                   8691:   /* double anprojf, mprojf, jprojf; */
1.267     brouard  8692:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8693:   double agec; /* generic age */
1.296     brouard  8694:   double agelim, ppij, yp,yp1,yp2;
1.126     brouard  8695:   double *popeffectif,*popcount;
                   8696:   double ***p3mat;
1.218     brouard  8697:   /* double ***mobaverage; */
1.126     brouard  8698:   char fileresf[FILENAMELENGTH];
                   8699: 
                   8700:   agelim=AGESUP;
1.211     brouard  8701:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8702:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8703:      We still use firstpass and lastpass as another selection.
                   8704:   */
1.214     brouard  8705:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8706:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8707:  
1.201     brouard  8708:   strcpy(fileresf,"F_"); 
                   8709:   strcat(fileresf,fileresu);
1.126     brouard  8710:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8711:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8712:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8713:   }
1.235     brouard  8714:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8715:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8716: 
1.225     brouard  8717:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8718: 
                   8719: 
                   8720:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8721:   if (stepm<=12) stepsize=1;
                   8722:   if(estepm < stepm){
                   8723:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8724:   }
1.270     brouard  8725:   else{
                   8726:     hstepm=estepm;   
                   8727:   }
                   8728:   if(estepm > stepm){ /* Yes every two year */
                   8729:     stepsize=2;
                   8730:   }
1.296     brouard  8731:   hstepm=hstepm/stepm;
1.126     brouard  8732: 
1.296     brouard  8733:   
                   8734:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8735:   /*                              fractional in yp1 *\/ */
                   8736:   /* aintmean=yp; */
                   8737:   /* yp2=modf((yp1*12),&yp); */
                   8738:   /* mintmean=yp; */
                   8739:   /* yp1=modf((yp2*30.5),&yp); */
                   8740:   /* jintmean=yp; */
                   8741:   /* if(jintmean==0) jintmean=1; */
                   8742:   /* if(mintmean==0) mintmean=1; */
1.126     brouard  8743: 
1.296     brouard  8744: 
                   8745:   /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */
                   8746:   /* date2dmy(dateprojd,&jprojd, &mprojd, &anprojd); */
                   8747:   /* date2dmy(dateprojf,&jprojf, &mprojf, &anprojf); */
1.227     brouard  8748:   i1=pow(2,cptcoveff);
1.126     brouard  8749:   if (cptcovn < 1){i1=1;}
                   8750:   
1.296     brouard  8751:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2); 
1.126     brouard  8752:   
                   8753:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8754:   
1.126     brouard  8755: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8756:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8757:   for(k=1; k<=i1;k++){
1.253     brouard  8758:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8759:       continue;
1.227     brouard  8760:     if(invalidvarcomb[k]){
                   8761:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8762:       continue;
                   8763:     }
                   8764:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8765:     for(j=1;j<=cptcoveff;j++) {
                   8766:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8767:     }
1.235     brouard  8768:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8769:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8770:     }
1.227     brouard  8771:     fprintf(ficresf," yearproj age");
                   8772:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8773:       for(i=1; i<=nlstate;i++)               
                   8774:        fprintf(ficresf," p%d%d",i,j);
                   8775:       fprintf(ficresf," wp.%d",j);
                   8776:     }
1.296     brouard  8777:     for (yearp=0; yearp<=(anprojf-anprojd);yearp +=stepsize) {
1.227     brouard  8778:       fprintf(ficresf,"\n");
1.296     brouard  8779:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jprojd,mprojd,anprojd+yearp);   
1.270     brouard  8780:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8781:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8782:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8783:        nhstepm = nhstepm/hstepm; 
                   8784:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8785:        oldm=oldms;savm=savms;
1.268     brouard  8786:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8787:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8788:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8789:        for (h=0; h<=nhstepm; h++){
                   8790:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8791:            break;
                   8792:          }
                   8793:        }
                   8794:        fprintf(ficresf,"\n");
                   8795:        for(j=1;j<=cptcoveff;j++) 
                   8796:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8797:        fprintf(ficresf,"%.f %.f ",anprojd+yearp,agec+h*hstepm/YEARM*stepm);
1.268     brouard  8798:        
                   8799:        for(j=1; j<=nlstate+ndeath;j++) {
                   8800:          ppij=0.;
                   8801:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8802:            if (mobilav>=1)
                   8803:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8804:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8805:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8806:            }
1.268     brouard  8807:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8808:          } /* end i */
                   8809:          fprintf(ficresf," %.3f", ppij);
                   8810:        }/* end j */
1.227     brouard  8811:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8812:       } /* end agec */
1.266     brouard  8813:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8814:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8815:     } /* end yearp */
                   8816:   } /* end  k */
1.219     brouard  8817:        
1.126     brouard  8818:   fclose(ficresf);
1.215     brouard  8819:   printf("End of Computing forecasting \n");
                   8820:   fprintf(ficlog,"End of Computing forecasting\n");
                   8821: 
1.126     brouard  8822: }
                   8823: 
1.269     brouard  8824: /************** Back Forecasting ******************/
1.296     brouard  8825:  /* void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
                   8826:  void prevbackforecast(char fileres[], double ***prevacurrent, double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8827:   /* back1, year, month, day of starting backprojection
1.267     brouard  8828:      agemin, agemax range of age
                   8829:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8830:      anback2 year of end of backprojection (same day and month as back1).
                   8831:      prevacurrent and prev are prevalences.
1.267     brouard  8832:   */
                   8833:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8834:   double agec; /* generic age */
1.302     brouard  8835:   double agelim, ppij, ppi, yp,yp1,yp2; /* ,jintmean,mintmean,aintmean;*/
1.267     brouard  8836:   double *popeffectif,*popcount;
                   8837:   double ***p3mat;
                   8838:   /* double ***mobaverage; */
                   8839:   char fileresfb[FILENAMELENGTH];
                   8840:  
1.268     brouard  8841:   agelim=AGEINF;
1.267     brouard  8842:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8843:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8844:      We still use firstpass and lastpass as another selection.
                   8845:   */
                   8846:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8847:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8848: 
                   8849:   /*Do we need to compute prevalence again?*/
                   8850: 
                   8851:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8852:   
                   8853:   strcpy(fileresfb,"FB_");
                   8854:   strcat(fileresfb,fileresu);
                   8855:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8856:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8857:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8858:   }
                   8859:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8860:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8861:   
                   8862:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8863:   
                   8864:    
                   8865:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8866:   if (stepm<=12) stepsize=1;
                   8867:   if(estepm < stepm){
                   8868:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8869:   }
1.270     brouard  8870:   else{
                   8871:     hstepm=estepm;   
                   8872:   }
                   8873:   if(estepm >= stepm){ /* Yes every two year */
                   8874:     stepsize=2;
                   8875:   }
1.267     brouard  8876:   
                   8877:   hstepm=hstepm/stepm;
1.296     brouard  8878:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8879:   /*                              fractional in yp1 *\/ */
                   8880:   /* aintmean=yp; */
                   8881:   /* yp2=modf((yp1*12),&yp); */
                   8882:   /* mintmean=yp; */
                   8883:   /* yp1=modf((yp2*30.5),&yp); */
                   8884:   /* jintmean=yp; */
                   8885:   /* if(jintmean==0) jintmean=1; */
                   8886:   /* if(mintmean==0) jintmean=1; */
1.267     brouard  8887:   
                   8888:   i1=pow(2,cptcoveff);
                   8889:   if (cptcovn < 1){i1=1;}
                   8890:   
1.296     brouard  8891:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
                   8892:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8893:   
                   8894:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8895:   
                   8896:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8897:   for(k=1; k<=i1;k++){
                   8898:     if(i1 != 1 && TKresult[nres]!= k)
                   8899:       continue;
                   8900:     if(invalidvarcomb[k]){
                   8901:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8902:       continue;
                   8903:     }
1.268     brouard  8904:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8905:     for(j=1;j<=cptcoveff;j++) {
                   8906:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8907:     }
                   8908:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8909:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8910:     }
                   8911:     fprintf(ficresfb," yearbproj age");
                   8912:     for(j=1; j<=nlstate+ndeath;j++){
                   8913:       for(i=1; i<=nlstate;i++)
1.268     brouard  8914:        fprintf(ficresfb," b%d%d",i,j);
                   8915:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8916:     }
1.296     brouard  8917:     for (yearp=0; yearp>=(anbackf-anbackd);yearp -=stepsize) {
1.267     brouard  8918:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8919:       fprintf(ficresfb,"\n");
1.296     brouard  8920:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jbackd,mbackd,anbackd+yearp);
1.273     brouard  8921:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8922:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8923:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8924:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8925:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8926:        nhstepm = nhstepm/hstepm;
                   8927:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8928:        oldm=oldms;savm=savms;
1.268     brouard  8929:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8930:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8931:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8932:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8933:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8934:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8935:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8936:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8937:            break;
                   8938:          }
                   8939:        }
                   8940:        fprintf(ficresfb,"\n");
                   8941:        for(j=1;j<=cptcoveff;j++)
                   8942:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8943:        fprintf(ficresfb,"%.f %.f ",anbackd+yearp,agec-h*hstepm/YEARM*stepm);
1.268     brouard  8944:        for(i=1; i<=nlstate+ndeath;i++) {
                   8945:          ppij=0.;ppi=0.;
                   8946:          for(j=1; j<=nlstate;j++) {
                   8947:            /* if (mobilav==1) */
1.269     brouard  8948:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8949:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8950:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8951:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8952:              /* else { */
                   8953:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8954:              /* } */
1.268     brouard  8955:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8956:          } /* end j */
                   8957:          if(ppi <0.99){
                   8958:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8959:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8960:          }
                   8961:          fprintf(ficresfb," %.3f", ppij);
                   8962:        }/* end j */
1.267     brouard  8963:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8964:       } /* end agec */
                   8965:     } /* end yearp */
                   8966:   } /* end k */
1.217     brouard  8967:   
1.267     brouard  8968:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8969:   
1.267     brouard  8970:   fclose(ficresfb);
                   8971:   printf("End of Computing Back forecasting \n");
                   8972:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8973:        
1.267     brouard  8974: }
1.217     brouard  8975: 
1.269     brouard  8976: /* Variance of prevalence limit: varprlim */
                   8977:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8978:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8979:  
                   8980:    char fileresvpl[FILENAMELENGTH];  
                   8981:    FILE *ficresvpl;
                   8982:    double **oldm, **savm;
                   8983:    double **varpl; /* Variances of prevalence limits by age */   
                   8984:    int i1, k, nres, j ;
                   8985:    
                   8986:     strcpy(fileresvpl,"VPL_");
                   8987:     strcat(fileresvpl,fileresu);
                   8988:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8989:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8990:       exit(0);
                   8991:     }
1.288     brouard  8992:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8993:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8994:     
                   8995:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8996:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8997:     
                   8998:     i1=pow(2,cptcoveff);
                   8999:     if (cptcovn < 1){i1=1;}
                   9000: 
                   9001:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9002:     for(k=1; k<=i1;k++){
                   9003:       if(i1 != 1 && TKresult[nres]!= k)
                   9004:        continue;
                   9005:       fprintf(ficresvpl,"\n#****** ");
                   9006:       printf("\n#****** ");
                   9007:       fprintf(ficlog,"\n#****** ");
                   9008:       for(j=1;j<=cptcoveff;j++) {
                   9009:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9010:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9011:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9012:       }
                   9013:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9014:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9015:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9016:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9017:       }        
                   9018:       fprintf(ficresvpl,"******\n");
                   9019:       printf("******\n");
                   9020:       fprintf(ficlog,"******\n");
                   9021:       
                   9022:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   9023:       oldm=oldms;savm=savms;
                   9024:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   9025:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   9026:       /*}*/
                   9027:     }
                   9028:     
                   9029:     fclose(ficresvpl);
1.288     brouard  9030:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   9031:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  9032: 
                   9033:  }
                   9034: /* Variance of back prevalence: varbprlim */
                   9035:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   9036:       /*------- Variance of back (stable) prevalence------*/
                   9037: 
                   9038:    char fileresvbl[FILENAMELENGTH];  
                   9039:    FILE  *ficresvbl;
                   9040: 
                   9041:    double **oldm, **savm;
                   9042:    double **varbpl; /* Variances of back prevalence limits by age */   
                   9043:    int i1, k, nres, j ;
                   9044: 
                   9045:    strcpy(fileresvbl,"VBL_");
                   9046:    strcat(fileresvbl,fileresu);
                   9047:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   9048:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   9049:      exit(0);
                   9050:    }
                   9051:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   9052:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   9053:    
                   9054:    
                   9055:    i1=pow(2,cptcoveff);
                   9056:    if (cptcovn < 1){i1=1;}
                   9057:    
                   9058:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9059:      for(k=1; k<=i1;k++){
                   9060:        if(i1 != 1 && TKresult[nres]!= k)
                   9061:         continue;
                   9062:        fprintf(ficresvbl,"\n#****** ");
                   9063:        printf("\n#****** ");
                   9064:        fprintf(ficlog,"\n#****** ");
                   9065:        for(j=1;j<=cptcoveff;j++) {
                   9066:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9067:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9068:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9069:        }
                   9070:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9071:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9072:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9073:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9074:        }
                   9075:        fprintf(ficresvbl,"******\n");
                   9076:        printf("******\n");
                   9077:        fprintf(ficlog,"******\n");
                   9078:        
                   9079:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   9080:        oldm=oldms;savm=savms;
                   9081:        
                   9082:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   9083:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   9084:        /*}*/
                   9085:      }
                   9086:    
                   9087:    fclose(ficresvbl);
                   9088:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   9089:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   9090: 
                   9091:  } /* End of varbprlim */
                   9092: 
1.126     brouard  9093: /************** Forecasting *****not tested NB*************/
1.227     brouard  9094: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  9095:   
1.227     brouard  9096: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   9097: /*   int *popage; */
                   9098: /*   double calagedatem, agelim, kk1, kk2; */
                   9099: /*   double *popeffectif,*popcount; */
                   9100: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   9101: /*   /\* double ***mobaverage; *\/ */
                   9102: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  9103: 
1.227     brouard  9104: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9105: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9106: /*   agelim=AGESUP; */
                   9107: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  9108:   
1.227     brouard  9109: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  9110:   
                   9111:   
1.227     brouard  9112: /*   strcpy(filerespop,"POP_");  */
                   9113: /*   strcat(filerespop,fileresu); */
                   9114: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   9115: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   9116: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   9117: /*   } */
                   9118: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   9119: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  9120: 
1.227     brouard  9121: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  9122: 
1.227     brouard  9123: /*   /\* if (mobilav!=0) { *\/ */
                   9124: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   9125: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   9126: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   9127: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   9128: /*   /\*   } *\/ */
                   9129: /*   /\* } *\/ */
1.126     brouard  9130: 
1.227     brouard  9131: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   9132: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  9133:   
1.227     brouard  9134: /*   agelim=AGESUP; */
1.126     brouard  9135:   
1.227     brouard  9136: /*   hstepm=1; */
                   9137: /*   hstepm=hstepm/stepm;  */
1.218     brouard  9138:        
1.227     brouard  9139: /*   if (popforecast==1) { */
                   9140: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   9141: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   9142: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   9143: /*     }  */
                   9144: /*     popage=ivector(0,AGESUP); */
                   9145: /*     popeffectif=vector(0,AGESUP); */
                   9146: /*     popcount=vector(0,AGESUP); */
1.126     brouard  9147:     
1.227     brouard  9148: /*     i=1;    */
                   9149: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  9150:     
1.227     brouard  9151: /*     imx=i; */
                   9152: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   9153: /*   } */
1.218     brouard  9154:   
1.227     brouard  9155: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   9156: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   9157: /*       k=k+1; */
                   9158: /*       fprintf(ficrespop,"\n#******"); */
                   9159: /*       for(j=1;j<=cptcoveff;j++) { */
                   9160: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   9161: /*       } */
                   9162: /*       fprintf(ficrespop,"******\n"); */
                   9163: /*       fprintf(ficrespop,"# Age"); */
                   9164: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   9165: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  9166:       
1.227     brouard  9167: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   9168: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  9169:        
1.227     brouard  9170: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   9171: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   9172: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  9173:          
1.227     brouard  9174: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9175: /*       oldm=oldms;savm=savms; */
                   9176: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  9177:          
1.227     brouard  9178: /*       for (h=0; h<=nhstepm; h++){ */
                   9179: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   9180: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   9181: /*         }  */
                   9182: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   9183: /*           kk1=0.;kk2=0; */
                   9184: /*           for(i=1; i<=nlstate;i++) {               */
                   9185: /*             if (mobilav==1)  */
                   9186: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   9187: /*             else { */
                   9188: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   9189: /*             } */
                   9190: /*           } */
                   9191: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   9192: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   9193: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   9194: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   9195: /*           } */
                   9196: /*         } */
                   9197: /*         for(i=1; i<=nlstate;i++){ */
                   9198: /*           kk1=0.; */
                   9199: /*           for(j=1; j<=nlstate;j++){ */
                   9200: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   9201: /*           } */
                   9202: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   9203: /*         } */
1.218     brouard  9204:            
1.227     brouard  9205: /*         if (h==(int)(calagedatem+12*cpt)) */
                   9206: /*           for(j=1; j<=nlstate;j++)  */
                   9207: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   9208: /*       } */
                   9209: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9210: /*     } */
                   9211: /*       } */
1.218     brouard  9212:       
1.227     brouard  9213: /*       /\******\/ */
1.218     brouard  9214:       
1.227     brouard  9215: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   9216: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   9217: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   9218: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   9219: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  9220:          
1.227     brouard  9221: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9222: /*       oldm=oldms;savm=savms; */
                   9223: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9224: /*       for (h=0; h<=nhstepm; h++){ */
                   9225: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   9226: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   9227: /*         }  */
                   9228: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   9229: /*           kk1=0.;kk2=0; */
                   9230: /*           for(i=1; i<=nlstate;i++) {               */
                   9231: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   9232: /*           } */
                   9233: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   9234: /*         } */
                   9235: /*       } */
                   9236: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9237: /*     } */
                   9238: /*       } */
                   9239: /*     }  */
                   9240: /*   } */
1.218     brouard  9241:   
1.227     brouard  9242: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  9243:   
1.227     brouard  9244: /*   if (popforecast==1) { */
                   9245: /*     free_ivector(popage,0,AGESUP); */
                   9246: /*     free_vector(popeffectif,0,AGESUP); */
                   9247: /*     free_vector(popcount,0,AGESUP); */
                   9248: /*   } */
                   9249: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9250: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9251: /*   fclose(ficrespop); */
                   9252: /* } /\* End of popforecast *\/ */
1.218     brouard  9253:  
1.126     brouard  9254: int fileappend(FILE *fichier, char *optionfich)
                   9255: {
                   9256:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   9257:     printf("Problem with file: %s\n", optionfich);
                   9258:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   9259:     return (0);
                   9260:   }
                   9261:   fflush(fichier);
                   9262:   return (1);
                   9263: }
                   9264: 
                   9265: 
                   9266: /**************** function prwizard **********************/
                   9267: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   9268: {
                   9269: 
                   9270:   /* Wizard to print covariance matrix template */
                   9271: 
1.164     brouard  9272:   char ca[32], cb[32];
                   9273:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  9274:   int numlinepar;
                   9275: 
                   9276:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9277:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9278:   for(i=1; i <=nlstate; i++){
                   9279:     jj=0;
                   9280:     for(j=1; j <=nlstate+ndeath; j++){
                   9281:       if(j==i) continue;
                   9282:       jj++;
                   9283:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   9284:       printf("%1d%1d",i,j);
                   9285:       fprintf(ficparo,"%1d%1d",i,j);
                   9286:       for(k=1; k<=ncovmodel;k++){
                   9287:        /*        printf(" %lf",param[i][j][k]); */
                   9288:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   9289:        printf(" 0.");
                   9290:        fprintf(ficparo," 0.");
                   9291:       }
                   9292:       printf("\n");
                   9293:       fprintf(ficparo,"\n");
                   9294:     }
                   9295:   }
                   9296:   printf("# Scales (for hessian or gradient estimation)\n");
                   9297:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   9298:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   9299:   for(i=1; i <=nlstate; i++){
                   9300:     jj=0;
                   9301:     for(j=1; j <=nlstate+ndeath; j++){
                   9302:       if(j==i) continue;
                   9303:       jj++;
                   9304:       fprintf(ficparo,"%1d%1d",i,j);
                   9305:       printf("%1d%1d",i,j);
                   9306:       fflush(stdout);
                   9307:       for(k=1; k<=ncovmodel;k++){
                   9308:        /*      printf(" %le",delti3[i][j][k]); */
                   9309:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   9310:        printf(" 0.");
                   9311:        fprintf(ficparo," 0.");
                   9312:       }
                   9313:       numlinepar++;
                   9314:       printf("\n");
                   9315:       fprintf(ficparo,"\n");
                   9316:     }
                   9317:   }
                   9318:   printf("# Covariance matrix\n");
                   9319: /* # 121 Var(a12)\n\ */
                   9320: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9321: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   9322: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   9323: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   9324: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   9325: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   9326: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   9327:   fflush(stdout);
                   9328:   fprintf(ficparo,"# Covariance matrix\n");
                   9329:   /* # 121 Var(a12)\n\ */
                   9330:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9331:   /* #   ...\n\ */
                   9332:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   9333:   
                   9334:   for(itimes=1;itimes<=2;itimes++){
                   9335:     jj=0;
                   9336:     for(i=1; i <=nlstate; i++){
                   9337:       for(j=1; j <=nlstate+ndeath; j++){
                   9338:        if(j==i) continue;
                   9339:        for(k=1; k<=ncovmodel;k++){
                   9340:          jj++;
                   9341:          ca[0]= k+'a'-1;ca[1]='\0';
                   9342:          if(itimes==1){
                   9343:            printf("#%1d%1d%d",i,j,k);
                   9344:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   9345:          }else{
                   9346:            printf("%1d%1d%d",i,j,k);
                   9347:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   9348:            /*  printf(" %.5le",matcov[i][j]); */
                   9349:          }
                   9350:          ll=0;
                   9351:          for(li=1;li <=nlstate; li++){
                   9352:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   9353:              if(lj==li) continue;
                   9354:              for(lk=1;lk<=ncovmodel;lk++){
                   9355:                ll++;
                   9356:                if(ll<=jj){
                   9357:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   9358:                  if(ll<jj){
                   9359:                    if(itimes==1){
                   9360:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9361:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9362:                    }else{
                   9363:                      printf(" 0.");
                   9364:                      fprintf(ficparo," 0.");
                   9365:                    }
                   9366:                  }else{
                   9367:                    if(itimes==1){
                   9368:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   9369:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   9370:                    }else{
                   9371:                      printf(" 0.");
                   9372:                      fprintf(ficparo," 0.");
                   9373:                    }
                   9374:                  }
                   9375:                }
                   9376:              } /* end lk */
                   9377:            } /* end lj */
                   9378:          } /* end li */
                   9379:          printf("\n");
                   9380:          fprintf(ficparo,"\n");
                   9381:          numlinepar++;
                   9382:        } /* end k*/
                   9383:       } /*end j */
                   9384:     } /* end i */
                   9385:   } /* end itimes */
                   9386: 
                   9387: } /* end of prwizard */
                   9388: /******************* Gompertz Likelihood ******************************/
                   9389: double gompertz(double x[])
                   9390: { 
1.302     brouard  9391:   double A=0.0,B=0.,L=0.0,sump=0.,num=0.;
1.126     brouard  9392:   int i,n=0; /* n is the size of the sample */
                   9393: 
1.220     brouard  9394:   for (i=1;i<=imx ; i++) {
1.126     brouard  9395:     sump=sump+weight[i];
                   9396:     /*    sump=sump+1;*/
                   9397:     num=num+1;
                   9398:   }
1.302     brouard  9399:   L=0.0;
                   9400:   /* agegomp=AGEGOMP; */
1.126     brouard  9401:   /* for (i=0; i<=imx; i++) 
                   9402:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9403: 
1.302     brouard  9404:   for (i=1;i<=imx ; i++) {
                   9405:     /* mu(a)=mu(agecomp)*exp(teta*(age-agegomp))
                   9406:        mu(a)=x[1]*exp(x[2]*(age-agegomp)); x[1] and x[2] are per year.
                   9407:      * L= Product mu(agedeces)exp(-\int_ageexam^agedc mu(u) du ) for a death between agedc (in month) 
                   9408:      *   and agedc +1 month, cens[i]=0: log(x[1]/YEARM)
                   9409:      * +
                   9410:      * exp(-\int_ageexam^agecens mu(u) du ) when censored, cens[i]=1
                   9411:      */
                   9412:      if (wav[i] > 1 || agedc[i] < AGESUP) {
                   9413:        if (cens[i] == 1){
                   9414:         A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   9415:        } else if (cens[i] == 0){
1.126     brouard  9416:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
1.302     brouard  9417:          +log(x[1]/YEARM) +x[2]*(agedc[i]-agegomp)+log(YEARM);
                   9418:       } else
                   9419:         printf("Gompertz cens[%d] neither 1 nor 0\n",i);
1.126     brouard  9420:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
1.302     brouard  9421:        L=L+A*weight[i];
1.126     brouard  9422:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
1.302     brouard  9423:      }
                   9424:   }
1.126     brouard  9425: 
1.302     brouard  9426:   /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
1.126     brouard  9427:  
                   9428:   return -2*L*num/sump;
                   9429: }
                   9430: 
1.136     brouard  9431: #ifdef GSL
                   9432: /******************* Gompertz_f Likelihood ******************************/
                   9433: double gompertz_f(const gsl_vector *v, void *params)
                   9434: { 
1.302     brouard  9435:   double A=0.,B=0.,LL=0.0,sump=0.,num=0.;
1.136     brouard  9436:   double *x= (double *) v->data;
                   9437:   int i,n=0; /* n is the size of the sample */
                   9438: 
                   9439:   for (i=0;i<=imx-1 ; i++) {
                   9440:     sump=sump+weight[i];
                   9441:     /*    sump=sump+1;*/
                   9442:     num=num+1;
                   9443:   }
                   9444:  
                   9445:  
                   9446:   /* for (i=0; i<=imx; i++) 
                   9447:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9448:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9449:   for (i=1;i<=imx ; i++)
                   9450:     {
                   9451:       if (cens[i] == 1 && wav[i]>1)
                   9452:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9453:       
                   9454:       if (cens[i] == 0 && wav[i]>1)
                   9455:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9456:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9457:       
                   9458:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9459:       if (wav[i] > 1 ) { /* ??? */
                   9460:        LL=LL+A*weight[i];
                   9461:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9462:       }
                   9463:     }
                   9464: 
                   9465:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9466:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9467:  
                   9468:   return -2*LL*num/sump;
                   9469: }
                   9470: #endif
                   9471: 
1.126     brouard  9472: /******************* Printing html file ***********/
1.201     brouard  9473: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9474:                  int lastpass, int stepm, int weightopt, char model[],\
                   9475:                  int imx,  double p[],double **matcov,double agemortsup){
                   9476:   int i,k;
                   9477: 
                   9478:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9479:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9480:   for (i=1;i<=2;i++) 
                   9481:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9482:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9483:   fprintf(fichtm,"</ul>");
                   9484: 
                   9485: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9486: 
                   9487:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9488: 
                   9489:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9490:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9491: 
                   9492:  
                   9493:   fflush(fichtm);
                   9494: }
                   9495: 
                   9496: /******************* Gnuplot file **************/
1.201     brouard  9497: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9498: 
                   9499:   char dirfileres[132],optfileres[132];
1.164     brouard  9500: 
1.126     brouard  9501:   int ng;
                   9502: 
                   9503: 
                   9504:   /*#ifdef windows */
                   9505:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9506:     /*#endif */
                   9507: 
                   9508: 
                   9509:   strcpy(dirfileres,optionfilefiname);
                   9510:   strcpy(optfileres,"vpl");
1.199     brouard  9511:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9512:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9513:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9514:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9515:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9516: 
                   9517: } 
                   9518: 
1.136     brouard  9519: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9520: {
1.126     brouard  9521: 
1.136     brouard  9522:   /*-------- data file ----------*/
                   9523:   FILE *fic;
                   9524:   char dummy[]="                         ";
1.240     brouard  9525:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9526:   int lstra;
1.136     brouard  9527:   int linei, month, year,iout;
1.302     brouard  9528:   int noffset=0; /* This is the offset if BOM data file */
1.136     brouard  9529:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9530:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9531:   char *stratrunc;
1.223     brouard  9532: 
1.240     brouard  9533:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9534:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9535: 
1.240     brouard  9536:   for(v=1; v <=ncovcol;v++){
                   9537:     DummyV[v]=0;
                   9538:     FixedV[v]=0;
                   9539:   }
                   9540:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9541:     DummyV[v]=1;
                   9542:     FixedV[v]=0;
                   9543:   }
                   9544:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9545:     DummyV[v]=0;
                   9546:     FixedV[v]=1;
                   9547:   }
                   9548:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9549:     DummyV[v]=1;
                   9550:     FixedV[v]=1;
                   9551:   }
                   9552:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9553:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9554:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9555:   }
1.126     brouard  9556: 
1.136     brouard  9557:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9558:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9559:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9560:   }
1.126     brouard  9561: 
1.302     brouard  9562:     /* Is it a BOM UTF-8 Windows file? */
                   9563:   /* First data line */
                   9564:   linei=0;
                   9565:   while(fgets(line, MAXLINE, fic)) {
                   9566:     noffset=0;
                   9567:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   9568:     {
                   9569:       noffset=noffset+3;
                   9570:       printf("# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);fflush(stdout);
                   9571:       fprintf(ficlog,"# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);
                   9572:       fflush(ficlog); return 1;
                   9573:     }
                   9574:     /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   9575:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
                   9576:     {
                   9577:       noffset=noffset+2;
1.304     brouard  9578:       printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9579:       fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9580:       fflush(ficlog); return 1;
                   9581:     }
                   9582:     else if( line[0] == 0 && line[1] == 0)
                   9583:     {
                   9584:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   9585:        noffset=noffset+4;
1.304     brouard  9586:        printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9587:        fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9588:        fflush(ficlog); return 1;
                   9589:       }
                   9590:     } else{
                   9591:       ;/*printf(" Not a BOM file\n");*/
                   9592:     }
                   9593:         /* If line starts with a # it is a comment */
                   9594:     if (line[noffset] == '#') {
                   9595:       linei=linei+1;
                   9596:       break;
                   9597:     }else{
                   9598:       break;
                   9599:     }
                   9600:   }
                   9601:   fclose(fic);
                   9602:   if((fic=fopen(datafile,"r"))==NULL)    {
                   9603:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9604:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
                   9605:   }
                   9606:   /* Not a Bom file */
                   9607:   
1.136     brouard  9608:   i=1;
                   9609:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9610:     linei=linei+1;
                   9611:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9612:       if(line[j] == '\t')
                   9613:        line[j] = ' ';
                   9614:     }
                   9615:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9616:       ;
                   9617:     };
                   9618:     line[j+1]=0;  /* Trims blanks at end of line */
                   9619:     if(line[0]=='#'){
                   9620:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9621:       printf("Comment line\n%s\n",line);
                   9622:       continue;
                   9623:     }
                   9624:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9625:     strcpy(line, linetmp);
1.223     brouard  9626:     
                   9627:     /* Loops on waves */
                   9628:     for (j=maxwav;j>=1;j--){
                   9629:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9630:        cutv(stra, strb, line, ' '); 
                   9631:        if(strb[0]=='.') { /* Missing value */
                   9632:          lval=-1;
                   9633:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9634:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9635:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9636:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9637:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9638:            return 1;
                   9639:          }
                   9640:        }else{
                   9641:          errno=0;
                   9642:          /* what_kind_of_number(strb); */
                   9643:          dval=strtod(strb,&endptr); 
                   9644:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9645:          /* if(strb != endptr && *endptr == '\0') */
                   9646:          /*    dval=dlval; */
                   9647:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9648:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9649:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9650:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9651:            return 1;
                   9652:          }
                   9653:          cotqvar[j][iv][i]=dval; 
                   9654:          cotvar[j][ntv+iv][i]=dval; 
                   9655:        }
                   9656:        strcpy(line,stra);
1.223     brouard  9657:       }/* end loop ntqv */
1.225     brouard  9658:       
1.223     brouard  9659:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9660:        cutv(stra, strb, line, ' '); 
                   9661:        if(strb[0]=='.') { /* Missing value */
                   9662:          lval=-1;
                   9663:        }else{
                   9664:          errno=0;
                   9665:          lval=strtol(strb,&endptr,10); 
                   9666:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9667:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9668:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9669:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9670:            return 1;
                   9671:          }
                   9672:        }
                   9673:        if(lval <-1 || lval >1){
                   9674:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.319     brouard  9675:  Should be a value of %d(nth) covariate of wave %d (0 should be the value for the reference and 1\n \
1.223     brouard  9676:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9677:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9678:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9679:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9680:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9681:  output of IMaCh is often meaningless.\n                               \
1.319     brouard  9682:  Exiting.\n",lval,linei, i,line,iv,j);
1.238     brouard  9683:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.319     brouard  9684:  Should be a value of %d(nth) covariate of wave %d (0 should be the value for the reference and 1\n \
1.223     brouard  9685:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9686:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9687:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9688:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9689:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9690:  output of IMaCh is often meaningless.\n                               \
1.319     brouard  9691:  Exiting.\n",lval,linei, i,line,iv,j);fflush(ficlog);
1.238     brouard  9692:          return 1;
                   9693:        }
                   9694:        cotvar[j][iv][i]=(double)(lval);
                   9695:        strcpy(line,stra);
1.223     brouard  9696:       }/* end loop ntv */
1.225     brouard  9697:       
1.223     brouard  9698:       /* Statuses  at wave */
1.137     brouard  9699:       cutv(stra, strb, line, ' '); 
1.223     brouard  9700:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9701:        lval=-1;
1.136     brouard  9702:       }else{
1.238     brouard  9703:        errno=0;
                   9704:        lval=strtol(strb,&endptr,10); 
                   9705:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9706:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9707:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9708:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9709:          return 1;
                   9710:        }
1.136     brouard  9711:       }
1.225     brouard  9712:       
1.136     brouard  9713:       s[j][i]=lval;
1.225     brouard  9714:       
1.223     brouard  9715:       /* Date of Interview */
1.136     brouard  9716:       strcpy(line,stra);
                   9717:       cutv(stra, strb,line,' ');
1.169     brouard  9718:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9719:       }
1.169     brouard  9720:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9721:        month=99;
                   9722:        year=9999;
1.136     brouard  9723:       }else{
1.225     brouard  9724:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9725:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9726:        return 1;
1.136     brouard  9727:       }
                   9728:       anint[j][i]= (double) year; 
1.302     brouard  9729:       mint[j][i]= (double)month;
                   9730:       /* if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){ */
                   9731:       /*       printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9732:       /*       fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9733:       /* } */
1.136     brouard  9734:       strcpy(line,stra);
1.223     brouard  9735:     } /* End loop on waves */
1.225     brouard  9736:     
1.223     brouard  9737:     /* Date of death */
1.136     brouard  9738:     cutv(stra, strb,line,' '); 
1.169     brouard  9739:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9740:     }
1.169     brouard  9741:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9742:       month=99;
                   9743:       year=9999;
                   9744:     }else{
1.141     brouard  9745:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9746:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9747:       return 1;
1.136     brouard  9748:     }
                   9749:     andc[i]=(double) year; 
                   9750:     moisdc[i]=(double) month; 
                   9751:     strcpy(line,stra);
                   9752:     
1.223     brouard  9753:     /* Date of birth */
1.136     brouard  9754:     cutv(stra, strb,line,' '); 
1.169     brouard  9755:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9756:     }
1.169     brouard  9757:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9758:       month=99;
                   9759:       year=9999;
                   9760:     }else{
1.141     brouard  9761:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9762:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9763:       return 1;
1.136     brouard  9764:     }
                   9765:     if (year==9999) {
1.141     brouard  9766:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9767:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9768:       return 1;
                   9769:       
1.136     brouard  9770:     }
                   9771:     annais[i]=(double)(year);
1.302     brouard  9772:     moisnais[i]=(double)(month);
                   9773:     for (j=1;j<=maxwav;j++){
                   9774:       if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){
                   9775:        printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j,(int)moisnais[i],(int)annais[i]);
                   9776:        fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j, (int)moisnais[i],(int)annais[i]);
                   9777:       }
                   9778:     }
                   9779: 
1.136     brouard  9780:     strcpy(line,stra);
1.225     brouard  9781:     
1.223     brouard  9782:     /* Sample weight */
1.136     brouard  9783:     cutv(stra, strb,line,' '); 
                   9784:     errno=0;
                   9785:     dval=strtod(strb,&endptr); 
                   9786:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9787:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9788:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9789:       fflush(ficlog);
                   9790:       return 1;
                   9791:     }
                   9792:     weight[i]=dval; 
                   9793:     strcpy(line,stra);
1.225     brouard  9794:     
1.223     brouard  9795:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9796:       cutv(stra, strb, line, ' '); 
                   9797:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9798:        lval=-1;
1.311     brouard  9799:        coqvar[iv][i]=NAN; 
                   9800:        covar[ncovcol+iv][i]=NAN; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9801:       }else{
1.225     brouard  9802:        errno=0;
                   9803:        /* what_kind_of_number(strb); */
                   9804:        dval=strtod(strb,&endptr);
                   9805:        /* if(strb != endptr && *endptr == '\0') */
                   9806:        /*   dval=dlval; */
                   9807:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9808:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9809:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9810:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9811:          return 1;
                   9812:        }
                   9813:        coqvar[iv][i]=dval; 
1.226     brouard  9814:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9815:       }
                   9816:       strcpy(line,stra);
                   9817:     }/* end loop nqv */
1.136     brouard  9818:     
1.223     brouard  9819:     /* Covariate values */
1.136     brouard  9820:     for (j=ncovcol;j>=1;j--){
                   9821:       cutv(stra, strb,line,' '); 
1.223     brouard  9822:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9823:        lval=-1;
1.136     brouard  9824:       }else{
1.225     brouard  9825:        errno=0;
                   9826:        lval=strtol(strb,&endptr,10); 
                   9827:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9828:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9829:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9830:          return 1;
                   9831:        }
1.136     brouard  9832:       }
                   9833:       if(lval <-1 || lval >1){
1.225     brouard  9834:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9835:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9836:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9837:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9838:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9839:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9840:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9841:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9842:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9843:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9844:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9845:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9846:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9847:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9848:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9849:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9850:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9851:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9852:        return 1;
1.136     brouard  9853:       }
                   9854:       covar[j][i]=(double)(lval);
                   9855:       strcpy(line,stra);
                   9856:     }  
                   9857:     lstra=strlen(stra);
1.225     brouard  9858:     
1.136     brouard  9859:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9860:       stratrunc = &(stra[lstra-9]);
                   9861:       num[i]=atol(stratrunc);
                   9862:     }
                   9863:     else
                   9864:       num[i]=atol(stra);
                   9865:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9866:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9867:     
                   9868:     i=i+1;
                   9869:   } /* End loop reading  data */
1.225     brouard  9870:   
1.136     brouard  9871:   *imax=i-1; /* Number of individuals */
                   9872:   fclose(fic);
1.225     brouard  9873:   
1.136     brouard  9874:   return (0);
1.164     brouard  9875:   /* endread: */
1.225     brouard  9876:   printf("Exiting readdata: ");
                   9877:   fclose(fic);
                   9878:   return (1);
1.223     brouard  9879: }
1.126     brouard  9880: 
1.234     brouard  9881: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9882:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9883:   while (*p2 == ' ')
1.234     brouard  9884:     p2++; 
                   9885:   /* while ((*p1++ = *p2++) !=0) */
                   9886:   /*   ; */
                   9887:   /* do */
                   9888:   /*   while (*p2 == ' ') */
                   9889:   /*     p2++; */
                   9890:   /* while (*p1++ == *p2++); */
                   9891:   *stri=p2; 
1.145     brouard  9892: }
                   9893: 
1.235     brouard  9894: int decoderesult ( char resultline[], int nres)
1.230     brouard  9895: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9896: {
1.235     brouard  9897:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9898:   char resultsav[MAXLINE];
1.234     brouard  9899:   int resultmodel[MAXLINE];
                   9900:   int modelresult[MAXLINE];
1.230     brouard  9901:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9902: 
1.234     brouard  9903:   removefirstspace(&resultline);
1.230     brouard  9904: 
                   9905:   if (strstr(resultline,"v") !=0){
                   9906:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9907:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9908:     return 1;
                   9909:   }
                   9910:   trimbb(resultsav, resultline);
                   9911:   if (strlen(resultsav) >1){
                   9912:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9913:   }
1.253     brouard  9914:   if(j == 0){ /* Resultline but no = */
                   9915:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9916:     return (0);
                   9917:   }
1.234     brouard  9918:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
1.318     brouard  9919:     printf("ERROR: the number of variables in this result line, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
1.310     brouard  9920:     fprintf(ficlog,"ERROR: the number of variables in the resultline, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
1.234     brouard  9921:   }
                   9922:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9923:     if(nbocc(resultsav,'=') >1){
1.318     brouard  9924:       cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' (stra is the rest of the resultline to be analyzed in the next loop *//*     resultsav= "V4=1 V5=25.1 V3=0" stra= "V5=25.1 V3=0" strb= "V4=1" */
                   9925:       cutl(strc,strd,strb,'=');  /* strb:"V4=1" strc="1" strd="V4" */
1.234     brouard  9926:     }else
                   9927:       cutl(strc,strd,resultsav,'=');
1.318     brouard  9928:     Tvalsel[k]=atof(strc); /* 1 */ /* Tvalsel of k is the float value of the kth covariate appearing in this result line */
1.234     brouard  9929:     
1.230     brouard  9930:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
1.318     brouard  9931:     Tvarsel[k]=atoi(strc);  /* 4 */ /* Tvarsel is the id of the kth covariate in the result line Tvarsel[1] in "V4=1.." is 4.*/
1.230     brouard  9932:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9933:     /* cptcovsel++;     */
                   9934:     if (nbocc(stra,'=') >0)
                   9935:       strcpy(resultsav,stra); /* and analyzes it */
                   9936:   }
1.235     brouard  9937:   /* Checking for missing or useless values in comparison of current model needs */
1.318     brouard  9938:   for(k1=1; k1<= cptcovt ;k1++){ /* Loop on model. model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9939:     if(Typevar[k1]==0){ /* Single covariate in model *//*0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.234     brouard  9940:       match=0;
1.318     brouard  9941:       for(k2=1; k2 <=j;k2++){/* Loop on resultline. In result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9942:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar is coming from the model, Tvarsel from the result. Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9943:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.318     brouard  9944:          match=1; /* modelresult of k2 variable of resultline is identical to k1 variable of the model good */
1.234     brouard  9945:          break;
                   9946:        }
                   9947:       }
                   9948:       if(match == 0){
1.310     brouard  9949:        printf("Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9950:        fprintf(ficlog,"Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9951:        return 1;
1.234     brouard  9952:       }
                   9953:     }
                   9954:   }
1.235     brouard  9955:   /* Checking for missing or useless values in comparison of current model needs */
1.318     brouard  9956:   for(k2=1; k2 <=j;k2++){ /* Loop on resultline variables: result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9957:     match=0;
1.318     brouard  9958:     for(k1=1; k1<= cptcovt ;k1++){ /* loop on model: model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.235     brouard  9959:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9960:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.318     brouard  9961:          resultmodel[k1]=k2;  /* k2th variable of the model corresponds to k1 variable of the model. resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9962:          ++match;
                   9963:        }
                   9964:       }
                   9965:     }
                   9966:     if(match == 0){
                   9967:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
1.310     brouard  9968:       fprintf(ficlog,"Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9969:       return 1;
1.234     brouard  9970:     }else if(match > 1){
                   9971:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
1.310     brouard  9972:       fprintf(ficlog,"Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9973:       return 1;
1.234     brouard  9974:     }
                   9975:   }
1.235     brouard  9976:       
1.234     brouard  9977:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9978:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9979:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9980:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9981:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9982:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9983:   /*    1 0 0 0 */
                   9984:   /*    2 1 0 0 */
                   9985:   /*    3 0 1 0 */ 
                   9986:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9987:   /*    5 0 0 1 */
                   9988:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9989:   /*    7 0 1 1 */
                   9990:   /*    8 1 1 1 */
1.237     brouard  9991:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9992:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9993:   /* V5*age V5 known which value for nres?  */
                   9994:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.318     brouard  9995:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* loop on model line */
1.235     brouard  9996:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9997:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9998:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9999:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  10000:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   10001:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   10002:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  10003:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   10004:       k4++;;
                   10005:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
1.318     brouard  10006:       k3q= resultmodel[k1]; /* resultmodel[1(V5)] = 25.1=k3q */
                   10007:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[1]]= Tvarsel[1] = 4=k2 */
1.237     brouard  10008:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   10009:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   10010:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  10011:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   10012:       k4q++;;
                   10013:     }
                   10014:   }
1.234     brouard  10015:   
1.235     brouard  10016:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  10017:   return (0);
                   10018: }
1.235     brouard  10019: 
1.230     brouard  10020: int decodemodel( char model[], int lastobs)
                   10021:  /**< This routine decodes the model and returns:
1.224     brouard  10022:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   10023:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   10024:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   10025:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   10026:        * - cptcovage number of covariates with age*products =2
                   10027:        * - cptcovs number of simple covariates
                   10028:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   10029:        *     which is a new column after the 9 (ncovcol) variables. 
1.319     brouard  10030:        * - if k is a product Vn*Vm, covar[k][i] is filled with correct values for each individual
1.224     brouard  10031:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   10032:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   10033:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   10034:        */
1.319     brouard  10035: /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1, Tage[1]=2 */
1.136     brouard  10036: {
1.238     brouard  10037:   int i, j, k, ks, v;
1.227     brouard  10038:   int  j1, k1, k2, k3, k4;
1.136     brouard  10039:   char modelsav[80];
1.145     brouard  10040:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  10041:   char *strpt;
1.136     brouard  10042: 
1.145     brouard  10043:   /*removespace(model);*/
1.136     brouard  10044:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  10045:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  10046:     if (strstr(model,"AGE") !=0){
1.192     brouard  10047:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   10048:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  10049:       return 1;
                   10050:     }
1.141     brouard  10051:     if (strstr(model,"v") !=0){
                   10052:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   10053:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   10054:       return 1;
                   10055:     }
1.187     brouard  10056:     strcpy(modelsav,model); 
                   10057:     if ((strpt=strstr(model,"age*age")) !=0){
                   10058:       printf(" strpt=%s, model=%s\n",strpt, model);
                   10059:       if(strpt != model){
1.234     brouard  10060:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  10061:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  10062:  corresponding column of parameters.\n",model);
1.234     brouard  10063:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  10064:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  10065:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  10066:        return 1;
1.225     brouard  10067:       }
1.187     brouard  10068:       nagesqr=1;
                   10069:       if (strstr(model,"+age*age") !=0)
1.234     brouard  10070:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  10071:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  10072:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  10073:       else 
1.234     brouard  10074:        substrchaine(modelsav, model, "age*age");
1.187     brouard  10075:     }else
                   10076:       nagesqr=0;
                   10077:     if (strlen(modelsav) >1){
                   10078:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   10079:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  10080:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  10081:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  10082:                     * cst, age and age*age 
                   10083:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   10084:       /* including age products which are counted in cptcovage.
                   10085:        * but the covariates which are products must be treated 
                   10086:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  10087:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   10088:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  10089:       
                   10090:       
1.187     brouard  10091:       /*   Design
                   10092:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   10093:        *  <          ncovcol=8                >
                   10094:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   10095:        *   k=  1    2      3       4     5       6      7        8
                   10096:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   10097:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  10098:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   10099:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  10100:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   10101:        *  Tage[++cptcovage]=k
                   10102:        *       if products, new covar are created after ncovcol with k1
                   10103:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   10104:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   10105:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   10106:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   10107:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   10108:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   10109:        *  <          ncovcol=8                >
                   10110:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   10111:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   10112:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
1.319     brouard  10113:        * p Tvar[1]@12={2,   1,     3,      3,  11,     10,     8,       8,   7,   8,   5,  6}
1.187     brouard  10114:        * p Tprod[1]@2={                         6, 5}
                   10115:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   10116:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   10117:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
1.319     brouard  10118:        *How to reorganize? Tvars(orted)
1.187     brouard  10119:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   10120:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   10121:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   10122:        * Struct []
                   10123:        */
1.225     brouard  10124:       
1.187     brouard  10125:       /* This loop fills the array Tvar from the string 'model'.*/
                   10126:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   10127:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   10128:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   10129:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   10130:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   10131:       /*       k=1 Tvar[1]=2 (from V2) */
                   10132:       /*       k=5 Tvar[5] */
                   10133:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  10134:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  10135:       /*       } */
1.198     brouard  10136:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  10137:       /*
                   10138:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  10139:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   10140:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   10141:       }
1.187     brouard  10142:       cptcovage=0;
1.319     brouard  10143:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model line */
                   10144:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' cutl from left to right
                   10145:                                         modelsav==V2+V1+V5*age+V4+V3*age strb=V3*age stra=V2+V1V5*age+V4 */    /* <model> "V5+V4+V3+V4*V3+V5*age+V1*age+V1" strb="V5" stra="V4+V3+V4*V3+V5*age+V1*age+V1" */
                   10146:        if (nbocc(modelsav,'+')==0)
                   10147:          strcpy(strb,modelsav); /* and analyzes it */
1.234     brouard  10148:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   10149:        /*scanf("%d",i);*/
1.319     brouard  10150:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V5*age+ V4+V3*age strb=V3*age */
                   10151:          cutl(strc,strd,strb,'*'); /**< k=1 strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
1.234     brouard  10152:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   10153:            /* covar is not filled and then is empty */
                   10154:            cptcovprod--;
                   10155:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
1.319     brouard  10156:            Tvar[k]=atoi(stre);  /* V2+V1+V5*age+V4+V3*age Tvar[5]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
1.234     brouard  10157:            Typevar[k]=1;  /* 1 for age product */
1.319     brouard  10158:            cptcovage++; /* Counts the number of covariates which include age as a product */
                   10159:            Tage[cptcovage]=k;  /*  V2+V1+V4+V3*age Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
1.234     brouard  10160:            /*printf("stre=%s ", stre);*/
                   10161:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   10162:            cptcovprod--;
                   10163:            cutl(stre,strb,strc,'V');
                   10164:            Tvar[k]=atoi(stre);
                   10165:            Typevar[k]=1;  /* 1 for age product */
                   10166:            cptcovage++;
                   10167:            Tage[cptcovage]=k;
                   10168:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   10169:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   10170:            cptcovn++;
                   10171:            cptcovprodnoage++;k1++;
                   10172:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   10173:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   10174:                                                because this model-covariate is a construction we invent a new column
                   10175:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
1.319     brouard  10176:                                                If already ncovcol=4 and model=V2 + V1 +V1*V4 +age*V3 +V3*V2
                   10177:                                                thus after V4 we invent V5 and V6 because age*V3 will be computed in 4
                   10178:                                                Tvar[3=V1*V4]=4+1=5 Tvar[5=V3*V2]=4 + 2= 6, Tvar[4=age*V3]=4 etc */
1.234     brouard  10179:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   10180:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   10181:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
1.319     brouard  10182:            Tposprod[k]=k1; /* Tposprod[3]=1, Tposprod[2]=5 */
1.234     brouard  10183:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   10184:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   10185:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   10186:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   10187:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  10188:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  10189:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   10190:            for (i=1; i<=lastobs;i++){
                   10191:              /* Computes the new covariate which is a product of
                   10192:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   10193:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   10194:            }
                   10195:          } /* End age is not in the model */
                   10196:        } /* End if model includes a product */
1.319     brouard  10197:        else { /* not a product */
1.234     brouard  10198:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   10199:          /*  scanf("%d",i);*/
                   10200:          cutl(strd,strc,strb,'V');
                   10201:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   10202:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   10203:          Tvar[k]=atoi(strd);
                   10204:          Typevar[k]=0;  /* 0 for simple covariates */
                   10205:        }
                   10206:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  10207:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  10208:                                  scanf("%d",i);*/
1.187     brouard  10209:       } /* end of loop + on total covariates */
                   10210:     } /* end if strlen(modelsave == 0) age*age might exist */
                   10211:   } /* end if strlen(model == 0) */
1.136     brouard  10212:   
                   10213:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   10214:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  10215:   
1.136     brouard  10216:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  10217:      printf("cptcovprod=%d ", cptcovprod);
                   10218:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   10219:      scanf("%d ",i);*/
                   10220: 
                   10221: 
1.230     brouard  10222: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   10223:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  10224: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   10225:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   10226:    k =           1    2   3     4       5       6      7      8        9
                   10227:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
1.319     brouard  10228:    Typevar[k]=   0    0   0     2       1       0      2      1        0
1.227     brouard  10229:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   10230:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   10231:          Tmodelind[combination of covar]=k;
1.225     brouard  10232: */  
                   10233: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  10234:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  10235:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  10236:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.318     brouard  10237:   printf("Model=1+age+%s\n\
1.227     brouard  10238: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   10239: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   10240: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.318     brouard  10241:   fprintf(ficlog,"Model=1+age+%s\n\
1.227     brouard  10242: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   10243: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   10244: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  10245:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  10246:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   10247:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  10248:       Fixed[k]= 0;
                   10249:       Dummy[k]= 0;
1.225     brouard  10250:       ncoveff++;
1.232     brouard  10251:       ncovf++;
1.234     brouard  10252:       nsd++;
                   10253:       modell[k].maintype= FTYPE;
                   10254:       TvarsD[nsd]=Tvar[k];
                   10255:       TvarsDind[nsd]=k;
                   10256:       TvarF[ncovf]=Tvar[k];
                   10257:       TvarFind[ncovf]=k;
                   10258:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10259:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10260:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   10261:       Fixed[k]= 0;
                   10262:       Dummy[k]= 0;
                   10263:       ncoveff++;
                   10264:       ncovf++;
                   10265:       modell[k].maintype= FTYPE;
                   10266:       TvarF[ncovf]=Tvar[k];
                   10267:       TvarFind[ncovf]=k;
1.230     brouard  10268:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  10269:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  10270:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  10271:       Fixed[k]= 0;
                   10272:       Dummy[k]= 1;
1.230     brouard  10273:       nqfveff++;
1.234     brouard  10274:       modell[k].maintype= FTYPE;
                   10275:       modell[k].subtype= FQ;
                   10276:       nsq++;
                   10277:       TvarsQ[nsq]=Tvar[k];
                   10278:       TvarsQind[nsq]=k;
1.232     brouard  10279:       ncovf++;
1.234     brouard  10280:       TvarF[ncovf]=Tvar[k];
                   10281:       TvarFind[ncovf]=k;
1.231     brouard  10282:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  10283:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  10284:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  10285:       Fixed[k]= 1;
                   10286:       Dummy[k]= 0;
1.225     brouard  10287:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  10288:       modell[k].maintype= VTYPE;
                   10289:       modell[k].subtype= VD;
                   10290:       nsd++;
                   10291:       TvarsD[nsd]=Tvar[k];
                   10292:       TvarsDind[nsd]=k;
                   10293:       ncovv++; /* Only simple time varying variables */
                   10294:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10295:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10296:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   10297:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  10298:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   10299:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  10300:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  10301:       Fixed[k]= 1;
                   10302:       Dummy[k]= 1;
                   10303:       nqtveff++;
                   10304:       modell[k].maintype= VTYPE;
                   10305:       modell[k].subtype= VQ;
                   10306:       ncovv++; /* Only simple time varying variables */
                   10307:       nsq++;
1.319     brouard  10308:       TvarsQ[nsq]=Tvar[k]; /* k=1 Tvar=5 nsq=1 TvarsQ[1]=5 */
1.234     brouard  10309:       TvarsQind[nsq]=k;
                   10310:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10311:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10312:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   10313:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  10314:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   10315:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   10316:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  10317:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  10318:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  10319:       ncova++;
                   10320:       TvarA[ncova]=Tvar[k];
                   10321:       TvarAind[ncova]=k;
1.231     brouard  10322:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  10323:        Fixed[k]= 2;
                   10324:        Dummy[k]= 2;
                   10325:        modell[k].maintype= ATYPE;
                   10326:        modell[k].subtype= APFD;
                   10327:        /* ncoveff++; */
1.227     brouard  10328:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  10329:        Fixed[k]= 2;
                   10330:        Dummy[k]= 3;
                   10331:        modell[k].maintype= ATYPE;
                   10332:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   10333:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  10334:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  10335:        Fixed[k]= 3;
                   10336:        Dummy[k]= 2;
                   10337:        modell[k].maintype= ATYPE;
                   10338:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   10339:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  10340:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10341:        Fixed[k]= 3;
                   10342:        Dummy[k]= 3;
                   10343:        modell[k].maintype= ATYPE;
                   10344:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   10345:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  10346:       }
                   10347:     }else if (Typevar[k] == 2) {  /* product without age */
                   10348:       k1=Tposprod[k];
                   10349:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  10350:        if(Tvard[k1][2] <=ncovcol){
                   10351:          Fixed[k]= 1;
                   10352:          Dummy[k]= 0;
                   10353:          modell[k].maintype= FTYPE;
                   10354:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   10355:          ncovf++; /* Fixed variables without age */
                   10356:          TvarF[ncovf]=Tvar[k];
                   10357:          TvarFind[ncovf]=k;
                   10358:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10359:          Fixed[k]= 0;  /* or 2 ?*/
                   10360:          Dummy[k]= 1;
                   10361:          modell[k].maintype= FTYPE;
                   10362:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   10363:          ncovf++; /* Varying variables without age */
                   10364:          TvarF[ncovf]=Tvar[k];
                   10365:          TvarFind[ncovf]=k;
                   10366:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10367:          Fixed[k]= 1;
                   10368:          Dummy[k]= 0;
                   10369:          modell[k].maintype= VTYPE;
                   10370:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   10371:          ncovv++; /* Varying variables without age */
                   10372:          TvarV[ncovv]=Tvar[k];
                   10373:          TvarVind[ncovv]=k;
                   10374:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10375:          Fixed[k]= 1;
                   10376:          Dummy[k]= 1;
                   10377:          modell[k].maintype= VTYPE;
                   10378:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   10379:          ncovv++; /* Varying variables without age */
                   10380:          TvarV[ncovv]=Tvar[k];
                   10381:          TvarVind[ncovv]=k;
                   10382:        }
1.227     brouard  10383:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  10384:        if(Tvard[k1][2] <=ncovcol){
                   10385:          Fixed[k]= 0;  /* or 2 ?*/
                   10386:          Dummy[k]= 1;
                   10387:          modell[k].maintype= FTYPE;
                   10388:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   10389:          ncovf++; /* Fixed variables without age */
                   10390:          TvarF[ncovf]=Tvar[k];
                   10391:          TvarFind[ncovf]=k;
                   10392:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10393:          Fixed[k]= 1;
                   10394:          Dummy[k]= 1;
                   10395:          modell[k].maintype= VTYPE;
                   10396:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   10397:          ncovv++; /* Varying variables without age */
                   10398:          TvarV[ncovv]=Tvar[k];
                   10399:          TvarVind[ncovv]=k;
                   10400:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10401:          Fixed[k]= 1;
                   10402:          Dummy[k]= 1;
                   10403:          modell[k].maintype= VTYPE;
                   10404:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   10405:          ncovv++; /* Varying variables without age */
                   10406:          TvarV[ncovv]=Tvar[k];
                   10407:          TvarVind[ncovv]=k;
                   10408:          ncovv++; /* Varying variables without age */
                   10409:          TvarV[ncovv]=Tvar[k];
                   10410:          TvarVind[ncovv]=k;
                   10411:        }
1.227     brouard  10412:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  10413:        if(Tvard[k1][2] <=ncovcol){
                   10414:          Fixed[k]= 1;
                   10415:          Dummy[k]= 1;
                   10416:          modell[k].maintype= VTYPE;
                   10417:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   10418:          ncovv++; /* Varying variables without age */
                   10419:          TvarV[ncovv]=Tvar[k];
                   10420:          TvarVind[ncovv]=k;
                   10421:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10422:          Fixed[k]= 1;
                   10423:          Dummy[k]= 1;
                   10424:          modell[k].maintype= VTYPE;
                   10425:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   10426:          ncovv++; /* Varying variables without age */
                   10427:          TvarV[ncovv]=Tvar[k];
                   10428:          TvarVind[ncovv]=k;
                   10429:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10430:          Fixed[k]= 1;
                   10431:          Dummy[k]= 0;
                   10432:          modell[k].maintype= VTYPE;
                   10433:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   10434:          ncovv++; /* Varying variables without age */
                   10435:          TvarV[ncovv]=Tvar[k];
                   10436:          TvarVind[ncovv]=k;
                   10437:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10438:          Fixed[k]= 1;
                   10439:          Dummy[k]= 1;
                   10440:          modell[k].maintype= VTYPE;
                   10441:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   10442:          ncovv++; /* Varying variables without age */
                   10443:          TvarV[ncovv]=Tvar[k];
                   10444:          TvarVind[ncovv]=k;
                   10445:        }
1.227     brouard  10446:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10447:        if(Tvard[k1][2] <=ncovcol){
                   10448:          Fixed[k]= 1;
                   10449:          Dummy[k]= 1;
                   10450:          modell[k].maintype= VTYPE;
                   10451:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   10452:          ncovv++; /* Varying variables without age */
                   10453:          TvarV[ncovv]=Tvar[k];
                   10454:          TvarVind[ncovv]=k;
                   10455:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10456:          Fixed[k]= 1;
                   10457:          Dummy[k]= 1;
                   10458:          modell[k].maintype= VTYPE;
                   10459:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   10460:          ncovv++; /* Varying variables without age */
                   10461:          TvarV[ncovv]=Tvar[k];
                   10462:          TvarVind[ncovv]=k;
                   10463:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10464:          Fixed[k]= 1;
                   10465:          Dummy[k]= 1;
                   10466:          modell[k].maintype= VTYPE;
                   10467:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   10468:          ncovv++; /* Varying variables without age */
                   10469:          TvarV[ncovv]=Tvar[k];
                   10470:          TvarVind[ncovv]=k;
                   10471:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10472:          Fixed[k]= 1;
                   10473:          Dummy[k]= 1;
                   10474:          modell[k].maintype= VTYPE;
                   10475:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10476:          ncovv++; /* Varying variables without age */
                   10477:          TvarV[ncovv]=Tvar[k];
                   10478:          TvarVind[ncovv]=k;
                   10479:        }
1.227     brouard  10480:       }else{
1.240     brouard  10481:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10482:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10483:       } /*end k1*/
1.225     brouard  10484:     }else{
1.226     brouard  10485:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10486:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10487:     }
1.227     brouard  10488:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10489:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10490:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10491:   }
                   10492:   /* Searching for doublons in the model */
                   10493:   for(k1=1; k1<= cptcovt;k1++){
                   10494:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10495:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10496:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10497:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10498:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10499:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10500:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10501:            return(1);
                   10502:          }
                   10503:        }else if (Typevar[k1] ==2){
                   10504:          k3=Tposprod[k1];
                   10505:          k4=Tposprod[k2];
                   10506:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10507:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10508:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10509:            return(1);
                   10510:          }
                   10511:        }
1.227     brouard  10512:       }
                   10513:     }
1.225     brouard  10514:   }
                   10515:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10516:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10517:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10518:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10519:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10520:   /*endread:*/
1.225     brouard  10521:   printf("Exiting decodemodel: ");
                   10522:   return (1);
1.136     brouard  10523: }
                   10524: 
1.169     brouard  10525: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10526: {/* Check ages at death */
1.136     brouard  10527:   int i, m;
1.218     brouard  10528:   int firstone=0;
                   10529:   
1.136     brouard  10530:   for (i=1; i<=imx; i++) {
                   10531:     for(m=2; (m<= maxwav); m++) {
                   10532:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10533:        anint[m][i]=9999;
1.216     brouard  10534:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10535:          s[m][i]=-1;
1.136     brouard  10536:       }
                   10537:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10538:        *nberr = *nberr + 1;
1.218     brouard  10539:        if(firstone == 0){
                   10540:          firstone=1;
1.260     brouard  10541:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10542:        }
1.262     brouard  10543:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10544:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10545:       }
                   10546:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10547:        (*nberr)++;
1.259     brouard  10548:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10549:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10550:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10551:       }
                   10552:     }
                   10553:   }
                   10554: 
                   10555:   for (i=1; i<=imx; i++)  {
                   10556:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10557:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10558:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10559:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10560:          if(agedc[i]>0){
                   10561:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10562:              agev[m][i]=agedc[i];
1.214     brouard  10563:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10564:            }else {
1.136     brouard  10565:              if ((int)andc[i]!=9999){
                   10566:                nbwarn++;
                   10567:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10568:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10569:                agev[m][i]=-1;
                   10570:              }
                   10571:            }
1.169     brouard  10572:          } /* agedc > 0 */
1.214     brouard  10573:        } /* end if */
1.136     brouard  10574:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10575:                                 years but with the precision of a month */
                   10576:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10577:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10578:            agev[m][i]=1;
                   10579:          else if(agev[m][i] < *agemin){ 
                   10580:            *agemin=agev[m][i];
                   10581:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10582:          }
                   10583:          else if(agev[m][i] >*agemax){
                   10584:            *agemax=agev[m][i];
1.156     brouard  10585:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10586:          }
                   10587:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10588:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10589:        } /* en if 9*/
1.136     brouard  10590:        else { /* =9 */
1.214     brouard  10591:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10592:          agev[m][i]=1;
                   10593:          s[m][i]=-1;
                   10594:        }
                   10595:       }
1.214     brouard  10596:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10597:        agev[m][i]=1;
1.214     brouard  10598:       else{
                   10599:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10600:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10601:        agev[m][i]=0;
                   10602:       }
                   10603:     } /* End for lastpass */
                   10604:   }
1.136     brouard  10605:     
                   10606:   for (i=1; i<=imx; i++)  {
                   10607:     for(m=firstpass; (m<=lastpass); m++){
                   10608:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10609:        (*nberr)++;
1.136     brouard  10610:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10611:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10612:        return 1;
                   10613:       }
                   10614:     }
                   10615:   }
                   10616: 
                   10617:   /*for (i=1; i<=imx; i++){
                   10618:   for (m=firstpass; (m<lastpass); m++){
                   10619:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10620: }
                   10621: 
                   10622: }*/
                   10623: 
                   10624: 
1.139     brouard  10625:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10626:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10627: 
                   10628:   return (0);
1.164     brouard  10629:  /* endread:*/
1.136     brouard  10630:     printf("Exiting calandcheckages: ");
                   10631:     return (1);
                   10632: }
                   10633: 
1.172     brouard  10634: #if defined(_MSC_VER)
                   10635: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10636: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10637: //#include "stdafx.h"
                   10638: //#include <stdio.h>
                   10639: //#include <tchar.h>
                   10640: //#include <windows.h>
                   10641: //#include <iostream>
                   10642: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10643: 
                   10644: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10645: 
                   10646: BOOL IsWow64()
                   10647: {
                   10648:        BOOL bIsWow64 = FALSE;
                   10649: 
                   10650:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10651:        //  (HANDLE, PBOOL);
                   10652: 
                   10653:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10654: 
                   10655:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10656:        const char funcName[] = "IsWow64Process";
                   10657:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10658:                GetProcAddress(module, funcName);
                   10659: 
                   10660:        if (NULL != fnIsWow64Process)
                   10661:        {
                   10662:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10663:                        &bIsWow64))
                   10664:                        //throw std::exception("Unknown error");
                   10665:                        printf("Unknown error\n");
                   10666:        }
                   10667:        return bIsWow64 != FALSE;
                   10668: }
                   10669: #endif
1.177     brouard  10670: 
1.191     brouard  10671: void syscompilerinfo(int logged)
1.292     brouard  10672: {
                   10673: #include <stdint.h>
                   10674: 
                   10675:   /* #include "syscompilerinfo.h"*/
1.185     brouard  10676:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10677:    /* /GS /W3 /Gy
                   10678:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10679:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10680:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10681:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10682:    */ 
                   10683:    /* 64 bits */
1.185     brouard  10684:    /*
                   10685:      /GS /W3 /Gy
                   10686:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10687:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10688:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10689:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10690:    /* Optimization are useless and O3 is slower than O2 */
                   10691:    /*
                   10692:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10693:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10694:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10695:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10696:    */
1.186     brouard  10697:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10698:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10699:       /PDB:"visual studio
                   10700:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10701:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10702:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10703:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10704:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10705:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10706:       uiAccess='false'"
                   10707:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10708:       /NOLOGO /TLBID:1
                   10709:    */
1.292     brouard  10710: 
                   10711: 
1.177     brouard  10712: #if defined __INTEL_COMPILER
1.178     brouard  10713: #if defined(__GNUC__)
                   10714:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10715: #endif
1.177     brouard  10716: #elif defined(__GNUC__) 
1.179     brouard  10717: #ifndef  __APPLE__
1.174     brouard  10718: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10719: #endif
1.177     brouard  10720:    struct utsname sysInfo;
1.178     brouard  10721:    int cross = CROSS;
                   10722:    if (cross){
                   10723:           printf("Cross-");
1.191     brouard  10724:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10725:    }
1.174     brouard  10726: #endif
                   10727: 
1.191     brouard  10728:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10729: #if defined(__clang__)
1.191     brouard  10730:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10731: #endif
                   10732: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10733:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10734: #endif
                   10735: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10736:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10737: #endif
                   10738: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10739:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10740: #endif
                   10741: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10742:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10743: #endif
                   10744: #if defined(_MSC_VER)
1.191     brouard  10745:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10746: #endif
                   10747: #if defined(__PGI)
1.191     brouard  10748:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10749: #endif
                   10750: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10751:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10752: #endif
1.191     brouard  10753:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10754:    
1.167     brouard  10755: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10756: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10757:     // Windows (x64 and x86)
1.191     brouard  10758:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10759: #elif __unix__ // all unices, not all compilers
                   10760:     // Unix
1.191     brouard  10761:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10762: #elif __linux__
                   10763:     // linux
1.191     brouard  10764:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10765: #elif __APPLE__
1.174     brouard  10766:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10767:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10768: #endif
                   10769: 
                   10770: /*  __MINGW32__          */
                   10771: /*  __CYGWIN__  */
                   10772: /* __MINGW64__  */
                   10773: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10774: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10775: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10776: /* _WIN64  // Defined for applications for Win64. */
                   10777: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10778: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10779: 
1.167     brouard  10780: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10781:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10782: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10783:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10784: #else
1.191     brouard  10785:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10786: #endif
                   10787: 
1.169     brouard  10788: #if defined(__GNUC__)
                   10789: # if defined(__GNUC_PATCHLEVEL__)
                   10790: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10791:                             + __GNUC_MINOR__ * 100 \
                   10792:                             + __GNUC_PATCHLEVEL__)
                   10793: # else
                   10794: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10795:                             + __GNUC_MINOR__ * 100)
                   10796: # endif
1.174     brouard  10797:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10798:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10799: 
                   10800:    if (uname(&sysInfo) != -1) {
                   10801:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10802:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10803:    }
                   10804:    else
                   10805:       perror("uname() error");
1.179     brouard  10806:    //#ifndef __INTEL_COMPILER 
                   10807: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10808:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10809:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10810: #endif
1.169     brouard  10811: #endif
1.172     brouard  10812: 
1.286     brouard  10813:    //   void main ()
1.172     brouard  10814:    //   {
1.169     brouard  10815: #if defined(_MSC_VER)
1.174     brouard  10816:    if (IsWow64()){
1.191     brouard  10817:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10818:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10819:    }
                   10820:    else{
1.191     brouard  10821:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10822:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10823:    }
1.172     brouard  10824:    //     printf("\nPress Enter to continue...");
                   10825:    //     getchar();
                   10826:    //   }
                   10827: 
1.169     brouard  10828: #endif
                   10829:    
1.167     brouard  10830: 
1.219     brouard  10831: }
1.136     brouard  10832: 
1.219     brouard  10833: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10834:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10835:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10836:   /* double ftolpl = 1.e-10; */
1.180     brouard  10837:   double age, agebase, agelim;
1.203     brouard  10838:   double tot;
1.180     brouard  10839: 
1.202     brouard  10840:   strcpy(filerespl,"PL_");
                   10841:   strcat(filerespl,fileresu);
                   10842:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10843:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10844:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10845:   }
1.288     brouard  10846:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10847:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10848:   pstamp(ficrespl);
1.288     brouard  10849:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10850:   fprintf(ficrespl,"#Age ");
                   10851:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10852:   fprintf(ficrespl,"\n");
1.180     brouard  10853:   
1.219     brouard  10854:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10855: 
1.219     brouard  10856:   agebase=ageminpar;
                   10857:   agelim=agemaxpar;
1.180     brouard  10858: 
1.227     brouard  10859:   /* i1=pow(2,ncoveff); */
1.234     brouard  10860:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10861:   if (cptcovn < 1){i1=1;}
1.180     brouard  10862: 
1.238     brouard  10863:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10864:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10865:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10866:        continue;
1.235     brouard  10867: 
1.238     brouard  10868:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10869:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10870:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10871:       /* k=k+1; */
                   10872:       /* to clean */
                   10873:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10874:       fprintf(ficrespl,"#******");
                   10875:       printf("#******");
                   10876:       fprintf(ficlog,"#******");
                   10877:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10878:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10879:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10880:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10881:       }
                   10882:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10883:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10884:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10885:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10886:       }
                   10887:       fprintf(ficrespl,"******\n");
                   10888:       printf("******\n");
                   10889:       fprintf(ficlog,"******\n");
                   10890:       if(invalidvarcomb[k]){
                   10891:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10892:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10893:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10894:        continue;
                   10895:       }
1.219     brouard  10896: 
1.238     brouard  10897:       fprintf(ficrespl,"#Age ");
                   10898:       for(j=1;j<=cptcoveff;j++) {
                   10899:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10900:       }
                   10901:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10902:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10903:     
1.238     brouard  10904:       for (age=agebase; age<=agelim; age++){
                   10905:        /* for (age=agebase; age<=agebase; age++){ */
                   10906:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10907:        fprintf(ficrespl,"%.0f ",age );
                   10908:        for(j=1;j<=cptcoveff;j++)
                   10909:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10910:        tot=0.;
                   10911:        for(i=1; i<=nlstate;i++){
                   10912:          tot +=  prlim[i][i];
                   10913:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10914:        }
                   10915:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10916:       } /* Age */
                   10917:       /* was end of cptcod */
                   10918:     } /* cptcov */
                   10919:   } /* nres */
1.219     brouard  10920:   return 0;
1.180     brouard  10921: }
                   10922: 
1.218     brouard  10923: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10924:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10925:        
                   10926:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10927:    * at any age between ageminpar and agemaxpar
                   10928:         */
1.235     brouard  10929:   int i, j, k, i1, nres=0 ;
1.217     brouard  10930:   /* double ftolpl = 1.e-10; */
                   10931:   double age, agebase, agelim;
                   10932:   double tot;
1.218     brouard  10933:   /* double ***mobaverage; */
                   10934:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10935: 
                   10936:   strcpy(fileresplb,"PLB_");
                   10937:   strcat(fileresplb,fileresu);
                   10938:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10939:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10940:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10941:   }
1.288     brouard  10942:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10943:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10944:   pstamp(ficresplb);
1.288     brouard  10945:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10946:   fprintf(ficresplb,"#Age ");
                   10947:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10948:   fprintf(ficresplb,"\n");
                   10949:   
1.218     brouard  10950:   
                   10951:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10952:   
                   10953:   agebase=ageminpar;
                   10954:   agelim=agemaxpar;
                   10955:   
                   10956:   
1.227     brouard  10957:   i1=pow(2,cptcoveff);
1.218     brouard  10958:   if (cptcovn < 1){i1=1;}
1.227     brouard  10959:   
1.238     brouard  10960:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10961:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10962:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10963:        continue;
                   10964:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10965:       fprintf(ficresplb,"#******");
                   10966:       printf("#******");
                   10967:       fprintf(ficlog,"#******");
                   10968:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10969:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10970:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10971:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10972:       }
                   10973:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10974:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10975:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10976:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10977:       }
                   10978:       fprintf(ficresplb,"******\n");
                   10979:       printf("******\n");
                   10980:       fprintf(ficlog,"******\n");
                   10981:       if(invalidvarcomb[k]){
                   10982:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10983:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10984:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10985:        continue;
                   10986:       }
1.218     brouard  10987:     
1.238     brouard  10988:       fprintf(ficresplb,"#Age ");
                   10989:       for(j=1;j<=cptcoveff;j++) {
                   10990:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10991:       }
                   10992:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10993:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10994:     
                   10995:     
1.238     brouard  10996:       for (age=agebase; age<=agelim; age++){
                   10997:        /* for (age=agebase; age<=agebase; age++){ */
                   10998:        if(mobilavproj > 0){
                   10999:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   11000:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  11001:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  11002:        }else if (mobilavproj == 0){
                   11003:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   11004:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   11005:          exit(1);
                   11006:        }else{
                   11007:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  11008:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  11009:          /* printf("TOTOT\n"); */
                   11010:           /* exit(1); */
1.238     brouard  11011:        }
                   11012:        fprintf(ficresplb,"%.0f ",age );
                   11013:        for(j=1;j<=cptcoveff;j++)
                   11014:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11015:        tot=0.;
                   11016:        for(i=1; i<=nlstate;i++){
                   11017:          tot +=  bprlim[i][i];
                   11018:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   11019:        }
                   11020:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   11021:       } /* Age */
                   11022:       /* was end of cptcod */
1.255     brouard  11023:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  11024:     } /* end of any combination */
                   11025:   } /* end of nres */  
1.218     brouard  11026:   /* hBijx(p, bage, fage); */
                   11027:   /* fclose(ficrespijb); */
                   11028:   
                   11029:   return 0;
1.217     brouard  11030: }
1.218     brouard  11031:  
1.180     brouard  11032: int hPijx(double *p, int bage, int fage){
                   11033:     /*------------- h Pij x at various ages ------------*/
                   11034: 
                   11035:   int stepsize;
                   11036:   int agelim;
                   11037:   int hstepm;
                   11038:   int nhstepm;
1.235     brouard  11039:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  11040: 
                   11041:   double agedeb;
                   11042:   double ***p3mat;
                   11043: 
1.201     brouard  11044:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  11045:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   11046:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   11047:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   11048:     }
                   11049:     printf("Computing pij: result on file '%s' \n", filerespij);
                   11050:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   11051:   
                   11052:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   11053:     /*if (stepm<=24) stepsize=2;*/
                   11054: 
                   11055:     agelim=AGESUP;
                   11056:     hstepm=stepsize*YEARM; /* Every year of age */
                   11057:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  11058:                
1.180     brouard  11059:     /* hstepm=1;   aff par mois*/
                   11060:     pstamp(ficrespij);
                   11061:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  11062:     i1= pow(2,cptcoveff);
1.218     brouard  11063:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   11064:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   11065:                /*      k=k+1;  */
1.235     brouard  11066:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11067:     for(k=1; k<=i1;k++){
1.253     brouard  11068:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11069:        continue;
1.183     brouard  11070:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  11071:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  11072:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11073:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   11074:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   11075:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   11076:       }
1.183     brouard  11077:       fprintf(ficrespij,"******\n");
                   11078:       
                   11079:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   11080:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   11081:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   11082:        
                   11083:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  11084:        
1.183     brouard  11085:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   11086:        oldm=oldms;savm=savms;
1.235     brouard  11087:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  11088:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   11089:        for(i=1; i<=nlstate;i++)
                   11090:          for(j=1; j<=nlstate+ndeath;j++)
                   11091:            fprintf(ficrespij," %1d-%1d",i,j);
                   11092:        fprintf(ficrespij,"\n");
                   11093:        for (h=0; h<=nhstepm; h++){
                   11094:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   11095:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  11096:          for(i=1; i<=nlstate;i++)
                   11097:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  11098:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  11099:          fprintf(ficrespij,"\n");
                   11100:        }
1.183     brouard  11101:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   11102:        fprintf(ficrespij,"\n");
                   11103:       }
1.180     brouard  11104:       /*}*/
                   11105:     }
1.218     brouard  11106:     return 0;
1.180     brouard  11107: }
1.218     brouard  11108:  
                   11109:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  11110:     /*------------- h Bij x at various ages ------------*/
                   11111: 
                   11112:   int stepsize;
1.218     brouard  11113:   /* int agelim; */
                   11114:        int ageminl;
1.217     brouard  11115:   int hstepm;
                   11116:   int nhstepm;
1.238     brouard  11117:   int h, i, i1, j, k, nres;
1.218     brouard  11118:        
1.217     brouard  11119:   double agedeb;
                   11120:   double ***p3mat;
1.218     brouard  11121:        
                   11122:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   11123:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   11124:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   11125:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   11126:   }
                   11127:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   11128:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   11129:   
                   11130:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   11131:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  11132:   
1.218     brouard  11133:   /* agelim=AGESUP; */
1.289     brouard  11134:   ageminl=AGEINF; /* was 30 */
1.218     brouard  11135:   hstepm=stepsize*YEARM; /* Every year of age */
                   11136:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   11137:   
                   11138:   /* hstepm=1;   aff par mois*/
                   11139:   pstamp(ficrespijb);
1.255     brouard  11140:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  11141:   i1= pow(2,cptcoveff);
1.218     brouard  11142:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   11143:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   11144:   /*   k=k+1;  */
1.238     brouard  11145:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   11146:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11147:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  11148:        continue;
                   11149:       fprintf(ficrespijb,"\n#****** ");
                   11150:       for(j=1;j<=cptcoveff;j++)
                   11151:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11152:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11153:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11154:       }
                   11155:       fprintf(ficrespijb,"******\n");
1.264     brouard  11156:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  11157:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   11158:        continue;
                   11159:       }
                   11160:       
                   11161:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   11162:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   11163:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
1.297     brouard  11164:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm+0.1)-1; /* Typically 20 years = 20*12/6=40 or 55*12/24=27.5-1.1=>27 */
                   11165:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 or 28*/
1.238     brouard  11166:        
                   11167:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   11168:        
1.266     brouard  11169:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   11170:        /* and memory limitations if stepm is small */
                   11171: 
1.238     brouard  11172:        /* oldm=oldms;savm=savms; */
                   11173:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  11174:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  11175:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  11176:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  11177:        for(i=1; i<=nlstate;i++)
                   11178:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  11179:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  11180:        fprintf(ficrespijb,"\n");
1.238     brouard  11181:        for (h=0; h<=nhstepm; h++){
                   11182:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   11183:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   11184:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   11185:          for(i=1; i<=nlstate;i++)
                   11186:            for(j=1; j<=nlstate+ndeath;j++)
                   11187:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   11188:          fprintf(ficrespijb,"\n");
                   11189:        }
                   11190:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   11191:        fprintf(ficrespijb,"\n");
                   11192:       } /* end age deb */
                   11193:     } /* end combination */
                   11194:   } /* end nres */
1.218     brouard  11195:   return 0;
                   11196:  } /*  hBijx */
1.217     brouard  11197: 
1.180     brouard  11198: 
1.136     brouard  11199: /***********************************************/
                   11200: /**************** Main Program *****************/
                   11201: /***********************************************/
                   11202: 
                   11203: int main(int argc, char *argv[])
                   11204: {
                   11205: #ifdef GSL
                   11206:   const gsl_multimin_fminimizer_type *T;
                   11207:   size_t iteri = 0, it;
                   11208:   int rval = GSL_CONTINUE;
                   11209:   int status = GSL_SUCCESS;
                   11210:   double ssval;
                   11211: #endif
                   11212:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  11213:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   11214:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  11215:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  11216:   int jj, ll, li, lj, lk;
1.136     brouard  11217:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  11218:   int num_filled;
1.136     brouard  11219:   int itimes;
                   11220:   int NDIM=2;
                   11221:   int vpopbased=0;
1.235     brouard  11222:   int nres=0;
1.258     brouard  11223:   int endishere=0;
1.277     brouard  11224:   int noffset=0;
1.274     brouard  11225:   int ncurrv=0; /* Temporary variable */
                   11226:   
1.164     brouard  11227:   char ca[32], cb[32];
1.136     brouard  11228:   /*  FILE *fichtm; *//* Html File */
                   11229:   /* FILE *ficgp;*/ /*Gnuplot File */
                   11230:   struct stat info;
1.191     brouard  11231:   double agedeb=0.;
1.194     brouard  11232: 
                   11233:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  11234:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  11235: 
1.165     brouard  11236:   double fret;
1.191     brouard  11237:   double dum=0.; /* Dummy variable */
1.136     brouard  11238:   double ***p3mat;
1.218     brouard  11239:   /* double ***mobaverage; */
1.319     brouard  11240:   double wald;
1.164     brouard  11241: 
                   11242:   char line[MAXLINE];
1.197     brouard  11243:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   11244: 
1.234     brouard  11245:   char  modeltemp[MAXLINE];
1.230     brouard  11246:   char resultline[MAXLINE];
                   11247:   
1.136     brouard  11248:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  11249:   char *tok, *val; /* pathtot */
1.290     brouard  11250:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  11251:   int c,  h , cpt, c2;
1.191     brouard  11252:   int jl=0;
                   11253:   int i1, j1, jk, stepsize=0;
1.194     brouard  11254:   int count=0;
                   11255: 
1.164     brouard  11256:   int *tab; 
1.136     brouard  11257:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.296     brouard  11258:   /* double anprojd, mprojd, jprojd; /\* For eventual projections *\/ */
                   11259:   /* double anprojf, mprojf, jprojf; */
                   11260:   /* double jintmean,mintmean,aintmean;   */
                   11261:   int prvforecast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11262:   int prvbackcast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11263:   double yrfproj= 10.0; /* Number of years of forward projections */
                   11264:   double yrbproj= 10.0; /* Number of years of backward projections */
                   11265:   int prevbcast=0; /* defined as global for mlikeli and mle, replacing backcast */
1.136     brouard  11266:   int mobilav=0,popforecast=0;
1.191     brouard  11267:   int hstepm=0, nhstepm=0;
1.136     brouard  11268:   int agemortsup;
                   11269:   float  sumlpop=0.;
                   11270:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   11271:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   11272: 
1.191     brouard  11273:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  11274:   double ftolpl=FTOL;
                   11275:   double **prlim;
1.217     brouard  11276:   double **bprlim;
1.317     brouard  11277:   double ***param; /* Matrix of parameters, param[i][j][k] param=ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel) 
                   11278:                     state of origin, state of destination including death, for each covariate: constante, age, and V1 V2 etc. */
1.251     brouard  11279:   double ***paramstart; /* Matrix of starting parameter values */
                   11280:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  11281:   double **matcov; /* Matrix of covariance */
1.203     brouard  11282:   double **hess; /* Hessian matrix */
1.136     brouard  11283:   double ***delti3; /* Scale */
                   11284:   double *delti; /* Scale */
                   11285:   double ***eij, ***vareij;
                   11286:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  11287: 
1.136     brouard  11288:   double *epj, vepp;
1.164     brouard  11289: 
1.273     brouard  11290:   double dateprev1, dateprev2;
1.296     brouard  11291:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0, dateprojd=0, dateprojf=0;
                   11292:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0, datebackd=0, datebackf=0;
                   11293: 
1.217     brouard  11294: 
1.136     brouard  11295:   double **ximort;
1.145     brouard  11296:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  11297:   int *dcwave;
                   11298: 
1.164     brouard  11299:   char z[1]="c";
1.136     brouard  11300: 
                   11301:   /*char  *strt;*/
                   11302:   char strtend[80];
1.126     brouard  11303: 
1.164     brouard  11304: 
1.126     brouard  11305: /*   setlocale (LC_ALL, ""); */
                   11306: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   11307: /*   textdomain (PACKAGE); */
                   11308: /*   setlocale (LC_CTYPE, ""); */
                   11309: /*   setlocale (LC_MESSAGES, ""); */
                   11310: 
                   11311:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  11312:   rstart_time = time(NULL);  
                   11313:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   11314:   start_time = *localtime(&rstart_time);
1.126     brouard  11315:   curr_time=start_time;
1.157     brouard  11316:   /*tml = *localtime(&start_time.tm_sec);*/
                   11317:   /* strcpy(strstart,asctime(&tml)); */
                   11318:   strcpy(strstart,asctime(&start_time));
1.126     brouard  11319: 
                   11320: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  11321: /*  tp.tm_sec = tp.tm_sec +86400; */
                   11322: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  11323: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   11324: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   11325: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  11326: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  11327: /*   strt=asctime(&tmg); */
                   11328: /*   printf("Time(after) =%s",strstart);  */
                   11329: /*  (void) time (&time_value);
                   11330: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   11331: *  tm = *localtime(&time_value);
                   11332: *  strstart=asctime(&tm);
                   11333: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   11334: */
                   11335: 
                   11336:   nberr=0; /* Number of errors and warnings */
                   11337:   nbwarn=0;
1.184     brouard  11338: #ifdef WIN32
                   11339:   _getcwd(pathcd, size);
                   11340: #else
1.126     brouard  11341:   getcwd(pathcd, size);
1.184     brouard  11342: #endif
1.191     brouard  11343:   syscompilerinfo(0);
1.196     brouard  11344:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  11345:   if(argc <=1){
                   11346:     printf("\nEnter the parameter file name: ");
1.205     brouard  11347:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   11348:       printf("ERROR Empty parameter file name\n");
                   11349:       goto end;
                   11350:     }
1.126     brouard  11351:     i=strlen(pathr);
                   11352:     if(pathr[i-1]=='\n')
                   11353:       pathr[i-1]='\0';
1.156     brouard  11354:     i=strlen(pathr);
1.205     brouard  11355:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  11356:       pathr[i-1]='\0';
1.205     brouard  11357:     }
                   11358:     i=strlen(pathr);
                   11359:     if( i==0 ){
                   11360:       printf("ERROR Empty parameter file name\n");
                   11361:       goto end;
                   11362:     }
                   11363:     for (tok = pathr; tok != NULL; ){
1.126     brouard  11364:       printf("Pathr |%s|\n",pathr);
                   11365:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   11366:       printf("val= |%s| pathr=%s\n",val,pathr);
                   11367:       strcpy (pathtot, val);
                   11368:       if(pathr[0] == '\0') break; /* Dirty */
                   11369:     }
                   11370:   }
1.281     brouard  11371:   else if (argc<=2){
                   11372:     strcpy(pathtot,argv[1]);
                   11373:   }
1.126     brouard  11374:   else{
                   11375:     strcpy(pathtot,argv[1]);
1.281     brouard  11376:     strcpy(z,argv[2]);
                   11377:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  11378:   }
                   11379:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   11380:   /*cygwin_split_path(pathtot,path,optionfile);
                   11381:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   11382:   /* cutv(path,optionfile,pathtot,'\\');*/
                   11383: 
                   11384:   /* Split argv[0], imach program to get pathimach */
                   11385:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   11386:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11387:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11388:  /*   strcpy(pathimach,argv[0]); */
                   11389:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   11390:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   11391:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  11392: #ifdef WIN32
                   11393:   _chdir(path); /* Can be a relative path */
                   11394:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   11395: #else
1.126     brouard  11396:   chdir(path); /* Can be a relative path */
1.184     brouard  11397:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   11398: #endif
                   11399:   printf("Current directory %s!\n",pathcd);
1.126     brouard  11400:   strcpy(command,"mkdir ");
                   11401:   strcat(command,optionfilefiname);
                   11402:   if((outcmd=system(command)) != 0){
1.169     brouard  11403:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  11404:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   11405:     /* fclose(ficlog); */
                   11406: /*     exit(1); */
                   11407:   }
                   11408: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   11409: /*     perror("mkdir"); */
                   11410: /*   } */
                   11411: 
                   11412:   /*-------- arguments in the command line --------*/
                   11413: 
1.186     brouard  11414:   /* Main Log file */
1.126     brouard  11415:   strcat(filelog, optionfilefiname);
                   11416:   strcat(filelog,".log");    /* */
                   11417:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   11418:     printf("Problem with logfile %s\n",filelog);
                   11419:     goto end;
                   11420:   }
                   11421:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  11422:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  11423:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   11424:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   11425:  path=%s \n\
                   11426:  optionfile=%s\n\
                   11427:  optionfilext=%s\n\
1.156     brouard  11428:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  11429: 
1.197     brouard  11430:   syscompilerinfo(1);
1.167     brouard  11431: 
1.126     brouard  11432:   printf("Local time (at start):%s",strstart);
                   11433:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   11434:   fflush(ficlog);
                   11435: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  11436: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  11437: 
                   11438:   /* */
                   11439:   strcpy(fileres,"r");
                   11440:   strcat(fileres, optionfilefiname);
1.201     brouard  11441:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  11442:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  11443:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  11444: 
1.186     brouard  11445:   /* Main ---------arguments file --------*/
1.126     brouard  11446: 
                   11447:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  11448:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   11449:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  11450:     fflush(ficlog);
1.149     brouard  11451:     /* goto end; */
                   11452:     exit(70); 
1.126     brouard  11453:   }
                   11454: 
                   11455:   strcpy(filereso,"o");
1.201     brouard  11456:   strcat(filereso,fileresu);
1.126     brouard  11457:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   11458:     printf("Problem with Output resultfile: %s\n", filereso);
                   11459:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   11460:     fflush(ficlog);
                   11461:     goto end;
                   11462:   }
1.278     brouard  11463:       /*-------- Rewriting parameter file ----------*/
                   11464:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   11465:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   11466:   strcat(rfileres,".");    /* */
                   11467:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11468:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   11469:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11470:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   11471:     fflush(ficlog);
                   11472:     goto end;
                   11473:   }
                   11474:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  11475: 
1.278     brouard  11476:                                      
1.126     brouard  11477:   /* Reads comments: lines beginning with '#' */
                   11478:   numlinepar=0;
1.277     brouard  11479:   /* Is it a BOM UTF-8 Windows file? */
                   11480:   /* First parameter line */
1.197     brouard  11481:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  11482:     noffset=0;
                   11483:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   11484:     {
                   11485:       noffset=noffset+3;
                   11486:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11487:     }
1.302     brouard  11488: /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   11489:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
1.277     brouard  11490:     {
                   11491:       noffset=noffset+2;
                   11492:       printf("# File is an UTF16BE BOM file\n");
                   11493:     }
                   11494:     else if( line[0] == 0 && line[1] == 0)
                   11495:     {
                   11496:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11497:        noffset=noffset+4;
                   11498:        printf("# File is an UTF16BE BOM file\n");
                   11499:       }
                   11500:     } else{
                   11501:       ;/*printf(" Not a BOM file\n");*/
                   11502:     }
                   11503:   
1.197     brouard  11504:     /* If line starts with a # it is a comment */
1.277     brouard  11505:     if (line[noffset] == '#') {
1.197     brouard  11506:       numlinepar++;
                   11507:       fputs(line,stdout);
                   11508:       fputs(line,ficparo);
1.278     brouard  11509:       fputs(line,ficres);
1.197     brouard  11510:       fputs(line,ficlog);
                   11511:       continue;
                   11512:     }else
                   11513:       break;
                   11514:   }
                   11515:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11516:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11517:     if (num_filled != 5) {
                   11518:       printf("Should be 5 parameters\n");
1.283     brouard  11519:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11520:     }
1.126     brouard  11521:     numlinepar++;
1.197     brouard  11522:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11523:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11524:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11525:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11526:   }
                   11527:   /* Second parameter line */
                   11528:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11529:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11530:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11531:     if (line[0] == '#') {
                   11532:       numlinepar++;
1.283     brouard  11533:       printf("%s",line);
                   11534:       fprintf(ficres,"%s",line);
                   11535:       fprintf(ficparo,"%s",line);
                   11536:       fprintf(ficlog,"%s",line);
1.197     brouard  11537:       continue;
                   11538:     }else
                   11539:       break;
                   11540:   }
1.223     brouard  11541:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11542:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11543:     if (num_filled != 11) {
                   11544:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11545:       printf("but line=%s\n",line);
1.283     brouard  11546:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11547:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11548:     }
1.286     brouard  11549:     if( lastpass > maxwav){
                   11550:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11551:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11552:       fflush(ficlog);
                   11553:       goto end;
                   11554:     }
                   11555:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11556:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11557:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11558:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11559:   }
1.203     brouard  11560:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11561:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11562:   /* Third parameter line */
                   11563:   while(fgets(line, MAXLINE, ficpar)) {
                   11564:     /* If line starts with a # it is a comment */
                   11565:     if (line[0] == '#') {
                   11566:       numlinepar++;
1.283     brouard  11567:       printf("%s",line);
                   11568:       fprintf(ficres,"%s",line);
                   11569:       fprintf(ficparo,"%s",line);
                   11570:       fprintf(ficlog,"%s",line);
1.197     brouard  11571:       continue;
                   11572:     }else
                   11573:       break;
                   11574:   }
1.201     brouard  11575:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11576:     if (num_filled != 1){
1.302     brouard  11577:       printf("ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
                   11578:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
1.197     brouard  11579:       model[0]='\0';
                   11580:       goto end;
                   11581:     }
                   11582:     else{
                   11583:       if (model[0]=='+'){
                   11584:        for(i=1; i<=strlen(model);i++)
                   11585:          modeltemp[i-1]=model[i];
1.201     brouard  11586:        strcpy(model,modeltemp); 
1.197     brouard  11587:       }
                   11588:     }
1.199     brouard  11589:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11590:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11591:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11592:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11593:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11594:   }
                   11595:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11596:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11597:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11598:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11599:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11600:   fflush(ficlog);
1.190     brouard  11601:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11602:   if(model[0]=='#'){
1.279     brouard  11603:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11604:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11605:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11606:     if(mle != -1){
1.279     brouard  11607:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11608:       exit(1);
                   11609:     }
                   11610:   }
1.126     brouard  11611:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11612:     ungetc(c,ficpar);
                   11613:     fgets(line, MAXLINE, ficpar);
                   11614:     numlinepar++;
1.195     brouard  11615:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11616:       z[0]=line[1];
                   11617:     }
                   11618:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11619:     fputs(line, stdout);
                   11620:     //puts(line);
1.126     brouard  11621:     fputs(line,ficparo);
                   11622:     fputs(line,ficlog);
                   11623:   }
                   11624:   ungetc(c,ficpar);
                   11625: 
                   11626:    
1.290     brouard  11627:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11628:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11629:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11630:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11631:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11632:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11633:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11634:   */
                   11635:   if (strlen(model)>1) 
1.187     brouard  11636:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11637:   else
1.187     brouard  11638:     ncovmodel=2; /* Constant and age */
1.133     brouard  11639:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11640:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11641:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11642:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11643:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11644:     fflush(stdout);
                   11645:     fclose (ficlog);
                   11646:     goto end;
                   11647:   }
1.126     brouard  11648:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11649:   delti=delti3[1][1];
                   11650:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11651:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11652: /* We could also provide initial parameters values giving by simple logistic regression 
                   11653:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11654:       /* for(i=1;i<nlstate;i++){ */
                   11655:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11656:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11657:       /* } */
1.126     brouard  11658:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11659:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11660:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11661:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11662:     fclose (ficparo);
                   11663:     fclose (ficlog);
                   11664:     goto end;
                   11665:     exit(0);
1.220     brouard  11666:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11667:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11668:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11669:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11670:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11671:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11672:     hess=matrix(1,npar,1,npar);
1.220     brouard  11673:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11674:     /* Read guessed parameters */
1.126     brouard  11675:     /* Reads comments: lines beginning with '#' */
                   11676:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11677:       ungetc(c,ficpar);
                   11678:       fgets(line, MAXLINE, ficpar);
                   11679:       numlinepar++;
1.141     brouard  11680:       fputs(line,stdout);
1.126     brouard  11681:       fputs(line,ficparo);
                   11682:       fputs(line,ficlog);
                   11683:     }
                   11684:     ungetc(c,ficpar);
                   11685:     
                   11686:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11687:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11688:     for(i=1; i <=nlstate; i++){
1.234     brouard  11689:       j=0;
1.126     brouard  11690:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11691:        if(jj==i) continue;
                   11692:        j++;
1.292     brouard  11693:        while((c=getc(ficpar))=='#' && c!= EOF){
                   11694:          ungetc(c,ficpar);
                   11695:          fgets(line, MAXLINE, ficpar);
                   11696:          numlinepar++;
                   11697:          fputs(line,stdout);
                   11698:          fputs(line,ficparo);
                   11699:          fputs(line,ficlog);
                   11700:        }
                   11701:        ungetc(c,ficpar);
1.234     brouard  11702:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11703:        if ((i1 != i) || (j1 != jj)){
                   11704:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11705: It might be a problem of design; if ncovcol and the model are correct\n \
                   11706: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11707:          exit(1);
                   11708:        }
                   11709:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11710:        if(mle==1)
                   11711:          printf("%1d%1d",i,jj);
                   11712:        fprintf(ficlog,"%1d%1d",i,jj);
                   11713:        for(k=1; k<=ncovmodel;k++){
                   11714:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11715:          if(mle==1){
                   11716:            printf(" %lf",param[i][j][k]);
                   11717:            fprintf(ficlog," %lf",param[i][j][k]);
                   11718:          }
                   11719:          else
                   11720:            fprintf(ficlog," %lf",param[i][j][k]);
                   11721:          fprintf(ficparo," %lf",param[i][j][k]);
                   11722:        }
                   11723:        fscanf(ficpar,"\n");
                   11724:        numlinepar++;
                   11725:        if(mle==1)
                   11726:          printf("\n");
                   11727:        fprintf(ficlog,"\n");
                   11728:        fprintf(ficparo,"\n");
1.126     brouard  11729:       }
                   11730:     }  
                   11731:     fflush(ficlog);
1.234     brouard  11732:     
1.251     brouard  11733:     /* Reads parameters values */
1.126     brouard  11734:     p=param[1][1];
1.251     brouard  11735:     pstart=paramstart[1][1];
1.126     brouard  11736:     
                   11737:     /* Reads comments: lines beginning with '#' */
                   11738:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11739:       ungetc(c,ficpar);
                   11740:       fgets(line, MAXLINE, ficpar);
                   11741:       numlinepar++;
1.141     brouard  11742:       fputs(line,stdout);
1.126     brouard  11743:       fputs(line,ficparo);
                   11744:       fputs(line,ficlog);
                   11745:     }
                   11746:     ungetc(c,ficpar);
                   11747: 
                   11748:     for(i=1; i <=nlstate; i++){
                   11749:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11750:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11751:        if ( (i1-i) * (j1-j) != 0){
                   11752:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11753:          exit(1);
                   11754:        }
                   11755:        printf("%1d%1d",i,j);
                   11756:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11757:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11758:        for(k=1; k<=ncovmodel;k++){
                   11759:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11760:          printf(" %le",delti3[i][j][k]);
                   11761:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11762:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11763:        }
                   11764:        fscanf(ficpar,"\n");
                   11765:        numlinepar++;
                   11766:        printf("\n");
                   11767:        fprintf(ficparo,"\n");
                   11768:        fprintf(ficlog,"\n");
1.126     brouard  11769:       }
                   11770:     }
                   11771:     fflush(ficlog);
1.234     brouard  11772:     
1.145     brouard  11773:     /* Reads covariance matrix */
1.126     brouard  11774:     delti=delti3[1][1];
1.220     brouard  11775:                
                   11776:                
1.126     brouard  11777:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11778:                
1.126     brouard  11779:     /* Reads comments: lines beginning with '#' */
                   11780:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11781:       ungetc(c,ficpar);
                   11782:       fgets(line, MAXLINE, ficpar);
                   11783:       numlinepar++;
1.141     brouard  11784:       fputs(line,stdout);
1.126     brouard  11785:       fputs(line,ficparo);
                   11786:       fputs(line,ficlog);
                   11787:     }
                   11788:     ungetc(c,ficpar);
1.220     brouard  11789:                
1.126     brouard  11790:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11791:     hess=matrix(1,npar,1,npar);
1.131     brouard  11792:     for(i=1; i <=npar; i++)
                   11793:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11794:                
1.194     brouard  11795:     /* Scans npar lines */
1.126     brouard  11796:     for(i=1; i <=npar; i++){
1.226     brouard  11797:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11798:       if(count != 3){
1.226     brouard  11799:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11800: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11801: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11802:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11803: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11804: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11805:        exit(1);
1.220     brouard  11806:       }else{
1.226     brouard  11807:        if(mle==1)
                   11808:          printf("%1d%1d%d",i1,j1,jk);
                   11809:       }
                   11810:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11811:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11812:       for(j=1; j <=i; j++){
1.226     brouard  11813:        fscanf(ficpar," %le",&matcov[i][j]);
                   11814:        if(mle==1){
                   11815:          printf(" %.5le",matcov[i][j]);
                   11816:        }
                   11817:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11818:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11819:       }
                   11820:       fscanf(ficpar,"\n");
                   11821:       numlinepar++;
                   11822:       if(mle==1)
1.220     brouard  11823:                                printf("\n");
1.126     brouard  11824:       fprintf(ficlog,"\n");
                   11825:       fprintf(ficparo,"\n");
                   11826:     }
1.194     brouard  11827:     /* End of read covariance matrix npar lines */
1.126     brouard  11828:     for(i=1; i <=npar; i++)
                   11829:       for(j=i+1;j<=npar;j++)
1.226     brouard  11830:        matcov[i][j]=matcov[j][i];
1.126     brouard  11831:     
                   11832:     if(mle==1)
                   11833:       printf("\n");
                   11834:     fprintf(ficlog,"\n");
                   11835:     
                   11836:     fflush(ficlog);
                   11837:     
                   11838:   }    /* End of mle != -3 */
1.218     brouard  11839:   
1.186     brouard  11840:   /*  Main data
                   11841:    */
1.290     brouard  11842:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11843:   /* num=lvector(1,n); */
                   11844:   /* moisnais=vector(1,n); */
                   11845:   /* annais=vector(1,n); */
                   11846:   /* moisdc=vector(1,n); */
                   11847:   /* andc=vector(1,n); */
                   11848:   /* weight=vector(1,n); */
                   11849:   /* agedc=vector(1,n); */
                   11850:   /* cod=ivector(1,n); */
                   11851:   /* for(i=1;i<=n;i++){ */
                   11852:   num=lvector(firstobs,lastobs);
                   11853:   moisnais=vector(firstobs,lastobs);
                   11854:   annais=vector(firstobs,lastobs);
                   11855:   moisdc=vector(firstobs,lastobs);
                   11856:   andc=vector(firstobs,lastobs);
                   11857:   weight=vector(firstobs,lastobs);
                   11858:   agedc=vector(firstobs,lastobs);
                   11859:   cod=ivector(firstobs,lastobs);
                   11860:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11861:     num[i]=0;
                   11862:     moisnais[i]=0;
                   11863:     annais[i]=0;
                   11864:     moisdc[i]=0;
                   11865:     andc[i]=0;
                   11866:     agedc[i]=0;
                   11867:     cod[i]=0;
                   11868:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11869:   }
1.290     brouard  11870:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11871:   anint=matrix(1,maxwav,firstobs,lastobs);
                   11872:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11873:   tab=ivector(1,NCOVMAX);
1.144     brouard  11874:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11875:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11876: 
1.136     brouard  11877:   /* Reads data from file datafile */
                   11878:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11879:     goto end;
                   11880: 
                   11881:   /* Calculation of the number of parameters from char model */
1.234     brouard  11882:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11883:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11884:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11885:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11886:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11887:   */
                   11888:   
                   11889:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11890:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11891:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11892:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11893:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11894:   TvarF=ivector(1,NCOVMAX); /*  */
                   11895:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11896:   TvarV=ivector(1,NCOVMAX); /*  */
                   11897:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11898:   TvarA=ivector(1,NCOVMAX); /*  */
                   11899:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11900:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11901:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11902:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11903:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11904:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11905:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11906:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11907:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11908: 
1.230     brouard  11909:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11910:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11911:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11912:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11913:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11914:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11915:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11916:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11917:   */
                   11918:   /* For model-covariate k tells which data-covariate to use but
                   11919:     because this model-covariate is a construction we invent a new column
                   11920:     ncovcol + k1
                   11921:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11922:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11923:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11924:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11925:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11926:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11927:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11928:   */
1.145     brouard  11929:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11930:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11931:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11932:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11933:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11934:                         4 covariates (3 plus signs)
                   11935:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11936:                      */  
1.230     brouard  11937:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11938:                                * individual dummy, fixed or varying:
                   11939:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11940:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11941:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11942:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11943:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11944:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11945:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11946:                                * individual quantitative, fixed or varying:
                   11947:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11948:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11949:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11950: /* Main decodemodel */
                   11951: 
1.187     brouard  11952: 
1.223     brouard  11953:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11954:     goto end;
                   11955: 
1.137     brouard  11956:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11957:     nbwarn++;
                   11958:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11959:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11960:   }
1.136     brouard  11961:     /*  if(mle==1){*/
1.137     brouard  11962:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11963:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11964:   }
                   11965: 
                   11966:     /*-calculation of age at interview from date of interview and age at death -*/
                   11967:   agev=matrix(1,maxwav,1,imx);
                   11968: 
                   11969:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11970:     goto end;
                   11971: 
1.126     brouard  11972: 
1.136     brouard  11973:   agegomp=(int)agemin;
1.290     brouard  11974:   free_vector(moisnais,firstobs,lastobs);
                   11975:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11976:   /* free_matrix(mint,1,maxwav,1,n);
                   11977:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11978:   /* free_vector(moisdc,1,n); */
                   11979:   /* free_vector(andc,1,n); */
1.145     brouard  11980:   /* */
                   11981:   
1.126     brouard  11982:   wav=ivector(1,imx);
1.214     brouard  11983:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11984:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11985:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11986:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11987:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11988:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11989:    
                   11990:   /* Concatenates waves */
1.214     brouard  11991:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11992:      Death is a valid wave (if date is known).
                   11993:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11994:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11995:      and mw[mi+1][i]. dh depends on stepm.
                   11996:   */
                   11997: 
1.126     brouard  11998:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11999:   /* Concatenates waves */
1.145     brouard  12000:  
1.290     brouard  12001:   free_vector(moisdc,firstobs,lastobs);
                   12002:   free_vector(andc,firstobs,lastobs);
1.215     brouard  12003: 
1.126     brouard  12004:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   12005:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   12006:   ncodemax[1]=1;
1.145     brouard  12007:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  12008:   cptcoveff=0;
1.220     brouard  12009:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   12010:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  12011:   }
                   12012:   
                   12013:   ncovcombmax=pow(2,cptcoveff);
                   12014:   invalidvarcomb=ivector(1, ncovcombmax); 
                   12015:   for(i=1;i<ncovcombmax;i++)
                   12016:     invalidvarcomb[i]=0;
                   12017:   
1.211     brouard  12018:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  12019:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  12020:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  12021:   
1.200     brouard  12022:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  12023:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  12024:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  12025:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   12026:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   12027:    * (currently 0 or 1) in the data.
                   12028:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   12029:    * corresponding modality (h,j).
                   12030:    */
                   12031: 
1.145     brouard  12032:   h=0;
                   12033:   /*if (cptcovn > 0) */
1.126     brouard  12034:   m=pow(2,cptcoveff);
                   12035:  
1.144     brouard  12036:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  12037:           * For k=4 covariates, h goes from 1 to m=2**k
                   12038:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   12039:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  12040:           *     h\k   1     2     3     4
1.143     brouard  12041:           *______________________________  
                   12042:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   12043:           *     2     2     1     1     1
                   12044:           *     3 i=2 1     2     1     1
                   12045:           *     4     2     2     1     1
                   12046:           *     5 i=3 1 i=2 1     2     1
                   12047:           *     6     2     1     2     1
                   12048:           *     7 i=4 1     2     2     1
                   12049:           *     8     2     2     2     1
1.197     brouard  12050:           *     9 i=5 1 i=3 1 i=2 1     2
                   12051:           *    10     2     1     1     2
                   12052:           *    11 i=6 1     2     1     2
                   12053:           *    12     2     2     1     2
                   12054:           *    13 i=7 1 i=4 1     2     2    
                   12055:           *    14     2     1     2     2
                   12056:           *    15 i=8 1     2     2     2
                   12057:           *    16     2     2     2     2
1.143     brouard  12058:           */
1.212     brouard  12059:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  12060:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   12061:      * and the value of each covariate?
                   12062:      * V1=1, V2=1, V3=2, V4=1 ?
                   12063:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   12064:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   12065:      * In order to get the real value in the data, we use nbcode
                   12066:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   12067:      * We are keeping this crazy system in order to be able (in the future?) 
                   12068:      * to have more than 2 values (0 or 1) for a covariate.
                   12069:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   12070:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   12071:      *              bbbbbbbb
                   12072:      *              76543210     
                   12073:      *   h-1        00000101 (6-1=5)
1.219     brouard  12074:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  12075:      *           &
                   12076:      *     1        00000001 (1)
1.219     brouard  12077:      *              00000000        = 1 & ((h-1) >> (k-1))
                   12078:      *          +1= 00000001 =1 
1.211     brouard  12079:      *
                   12080:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   12081:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   12082:      *    >>k'            11
                   12083:      *          &   00000001
                   12084:      *            = 00000001
                   12085:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   12086:      * Reverse h=6 and m=16?
                   12087:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   12088:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   12089:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   12090:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   12091:      * V3=decodtabm(14,3,2**4)=2
                   12092:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   12093:      *(h-1) >> (j-1)    0011 =13 >> 2
                   12094:      *          &1 000000001
                   12095:      *           = 000000001
                   12096:      *         +1= 000000010 =2
                   12097:      *                  2211
                   12098:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   12099:      *                  V3=2
1.220     brouard  12100:                 * codtabm and decodtabm are identical
1.211     brouard  12101:      */
                   12102: 
1.145     brouard  12103: 
                   12104:  free_ivector(Ndum,-1,NCOVMAX);
                   12105: 
                   12106: 
1.126     brouard  12107:     
1.186     brouard  12108:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  12109:   strcpy(optionfilegnuplot,optionfilefiname);
                   12110:   if(mle==-3)
1.201     brouard  12111:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  12112:   strcat(optionfilegnuplot,".gp");
                   12113: 
                   12114:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   12115:     printf("Problem with file %s",optionfilegnuplot);
                   12116:   }
                   12117:   else{
1.204     brouard  12118:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  12119:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  12120:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   12121:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  12122:   }
                   12123:   /*  fclose(ficgp);*/
1.186     brouard  12124: 
                   12125: 
                   12126:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  12127: 
                   12128:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   12129:   if(mle==-3)
1.201     brouard  12130:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  12131:   strcat(optionfilehtm,".htm");
                   12132:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  12133:     printf("Problem with %s \n",optionfilehtm);
                   12134:     exit(0);
1.126     brouard  12135:   }
                   12136: 
                   12137:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   12138:   strcat(optionfilehtmcov,"-cov.htm");
                   12139:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   12140:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   12141:   }
                   12142:   else{
                   12143:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   12144: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  12145: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  12146:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   12147:   }
                   12148: 
1.213     brouard  12149:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  12150: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   12151: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  12152: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  12153: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  12154: \n\
                   12155: <hr  size=\"2\" color=\"#EC5E5E\">\
                   12156:  <ul><li><h4>Parameter files</h4>\n\
                   12157:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   12158:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   12159:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   12160:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   12161:  - Date and time at start: %s</ul>\n",\
                   12162:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   12163:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   12164:          fileres,fileres,\
                   12165:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   12166:   fflush(fichtm);
                   12167: 
                   12168:   strcpy(pathr,path);
                   12169:   strcat(pathr,optionfilefiname);
1.184     brouard  12170: #ifdef WIN32
                   12171:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   12172: #else
1.126     brouard  12173:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  12174: #endif
                   12175:          
1.126     brouard  12176:   
1.220     brouard  12177:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   12178:                 and for any valid combination of covariates
1.126     brouard  12179:      and prints on file fileres'p'. */
1.251     brouard  12180:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  12181:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  12182: 
                   12183:   fprintf(fichtm,"\n");
1.286     brouard  12184:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  12185:          ftol, stepm);
                   12186:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   12187:   ncurrv=1;
                   12188:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   12189:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   12190:   ncurrv=i;
                   12191:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  12192:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  12193:   ncurrv=i;
                   12194:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  12195:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  12196:   ncurrv=i;
                   12197:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   12198:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   12199:           nlstate, ndeath, maxwav, mle, weightopt);
                   12200: 
                   12201:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   12202: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   12203: 
                   12204:   
1.317     brouard  12205:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Number of (used) observations=%d <br>\n\
1.126     brouard  12206: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   12207: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  12208:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  12209:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  12210:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   12211:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   12212:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   12213:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  12214: 
1.126     brouard  12215:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   12216:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   12217:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   12218: 
                   12219:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  12220:   /* For mortality only */
1.126     brouard  12221:   if (mle==-3){
1.136     brouard  12222:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  12223:     for(i=1;i<=NDIM;i++)
                   12224:       for(j=1;j<=NDIM;j++)
                   12225:        ximort[i][j]=0.;
1.186     brouard  12226:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  12227:     cens=ivector(firstobs,lastobs);
                   12228:     ageexmed=vector(firstobs,lastobs);
                   12229:     agecens=vector(firstobs,lastobs);
                   12230:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  12231:                
1.126     brouard  12232:     for (i=1; i<=imx; i++){
                   12233:       dcwave[i]=-1;
                   12234:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  12235:        if (s[m][i]>nlstate) {
                   12236:          dcwave[i]=m;
                   12237:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   12238:          break;
                   12239:        }
1.126     brouard  12240:     }
1.226     brouard  12241:     
1.126     brouard  12242:     for (i=1; i<=imx; i++) {
                   12243:       if (wav[i]>0){
1.226     brouard  12244:        ageexmed[i]=agev[mw[1][i]][i];
                   12245:        j=wav[i];
                   12246:        agecens[i]=1.; 
                   12247:        
                   12248:        if (ageexmed[i]> 1 && wav[i] > 0){
                   12249:          agecens[i]=agev[mw[j][i]][i];
                   12250:          cens[i]= 1;
                   12251:        }else if (ageexmed[i]< 1) 
                   12252:          cens[i]= -1;
                   12253:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   12254:          cens[i]=0 ;
1.126     brouard  12255:       }
                   12256:       else cens[i]=-1;
                   12257:     }
                   12258:     
                   12259:     for (i=1;i<=NDIM;i++) {
                   12260:       for (j=1;j<=NDIM;j++)
1.226     brouard  12261:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  12262:     }
                   12263:     
1.302     brouard  12264:     p[1]=0.0268; p[NDIM]=0.083;
                   12265:     /* printf("%lf %lf", p[1], p[2]); */
1.126     brouard  12266:     
                   12267:     
1.136     brouard  12268: #ifdef GSL
                   12269:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  12270: #else
1.126     brouard  12271:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  12272: #endif
1.201     brouard  12273:     strcpy(filerespow,"POW-MORT_"); 
                   12274:     strcat(filerespow,fileresu);
1.126     brouard  12275:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   12276:       printf("Problem with resultfile: %s\n", filerespow);
                   12277:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   12278:     }
1.136     brouard  12279: #ifdef GSL
                   12280:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  12281: #else
1.126     brouard  12282:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  12283: #endif
1.126     brouard  12284:     /*  for (i=1;i<=nlstate;i++)
                   12285:        for(j=1;j<=nlstate+ndeath;j++)
                   12286:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   12287:     */
                   12288:     fprintf(ficrespow,"\n");
1.136     brouard  12289: #ifdef GSL
                   12290:     /* gsl starts here */ 
                   12291:     T = gsl_multimin_fminimizer_nmsimplex;
                   12292:     gsl_multimin_fminimizer *sfm = NULL;
                   12293:     gsl_vector *ss, *x;
                   12294:     gsl_multimin_function minex_func;
                   12295: 
                   12296:     /* Initial vertex size vector */
                   12297:     ss = gsl_vector_alloc (NDIM);
                   12298:     
                   12299:     if (ss == NULL){
                   12300:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   12301:     }
                   12302:     /* Set all step sizes to 1 */
                   12303:     gsl_vector_set_all (ss, 0.001);
                   12304: 
                   12305:     /* Starting point */
1.126     brouard  12306:     
1.136     brouard  12307:     x = gsl_vector_alloc (NDIM);
                   12308:     
                   12309:     if (x == NULL){
                   12310:       gsl_vector_free(ss);
                   12311:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   12312:     }
                   12313:   
                   12314:     /* Initialize method and iterate */
                   12315:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  12316:     /*     gsl_vector_set(x, 0, 0.0268); */
                   12317:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  12318:     gsl_vector_set(x, 0, p[1]);
                   12319:     gsl_vector_set(x, 1, p[2]);
                   12320: 
                   12321:     minex_func.f = &gompertz_f;
                   12322:     minex_func.n = NDIM;
                   12323:     minex_func.params = (void *)&p; /* ??? */
                   12324:     
                   12325:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   12326:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   12327:     
                   12328:     printf("Iterations beginning .....\n\n");
                   12329:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   12330: 
                   12331:     iteri=0;
                   12332:     while (rval == GSL_CONTINUE){
                   12333:       iteri++;
                   12334:       status = gsl_multimin_fminimizer_iterate(sfm);
                   12335:       
                   12336:       if (status) printf("error: %s\n", gsl_strerror (status));
                   12337:       fflush(0);
                   12338:       
                   12339:       if (status) 
                   12340:         break;
                   12341:       
                   12342:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   12343:       ssval = gsl_multimin_fminimizer_size (sfm);
                   12344:       
                   12345:       if (rval == GSL_SUCCESS)
                   12346:         printf ("converged to a local maximum at\n");
                   12347:       
                   12348:       printf("%5d ", iteri);
                   12349:       for (it = 0; it < NDIM; it++){
                   12350:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   12351:       }
                   12352:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   12353:     }
                   12354:     
                   12355:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   12356:     
                   12357:     gsl_vector_free(x); /* initial values */
                   12358:     gsl_vector_free(ss); /* inital step size */
                   12359:     for (it=0; it<NDIM; it++){
                   12360:       p[it+1]=gsl_vector_get(sfm->x,it);
                   12361:       fprintf(ficrespow," %.12lf", p[it]);
                   12362:     }
                   12363:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   12364: #endif
                   12365: #ifdef POWELL
                   12366:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   12367: #endif  
1.126     brouard  12368:     fclose(ficrespow);
                   12369:     
1.203     brouard  12370:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  12371: 
                   12372:     for(i=1; i <=NDIM; i++)
                   12373:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  12374:                                matcov[i][j]=matcov[j][i];
1.126     brouard  12375:     
                   12376:     printf("\nCovariance matrix\n ");
1.203     brouard  12377:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  12378:     for(i=1; i <=NDIM; i++) {
                   12379:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  12380:                                printf("%f ",matcov[i][j]);
                   12381:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  12382:       }
1.203     brouard  12383:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  12384:     }
                   12385:     
                   12386:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  12387:     for (i=1;i<=NDIM;i++) {
1.126     brouard  12388:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  12389:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   12390:     }
1.302     brouard  12391:     lsurv=vector(agegomp,AGESUP);
                   12392:     lpop=vector(agegomp,AGESUP);
                   12393:     tpop=vector(agegomp,AGESUP);
1.126     brouard  12394:     lsurv[agegomp]=100000;
                   12395:     
                   12396:     for (k=agegomp;k<=AGESUP;k++) {
                   12397:       agemortsup=k;
                   12398:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   12399:     }
                   12400:     
                   12401:     for (k=agegomp;k<agemortsup;k++)
                   12402:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   12403:     
                   12404:     for (k=agegomp;k<agemortsup;k++){
                   12405:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   12406:       sumlpop=sumlpop+lpop[k];
                   12407:     }
                   12408:     
                   12409:     tpop[agegomp]=sumlpop;
                   12410:     for (k=agegomp;k<(agemortsup-3);k++){
                   12411:       /*  tpop[k+1]=2;*/
                   12412:       tpop[k+1]=tpop[k]-lpop[k];
                   12413:     }
                   12414:     
                   12415:     
                   12416:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   12417:     for (k=agegomp;k<(agemortsup-2);k++) 
                   12418:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   12419:     
                   12420:     
                   12421:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  12422:                ageminpar=50;
                   12423:                agemaxpar=100;
1.194     brouard  12424:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   12425:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12426: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12427: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   12428:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12429: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12430: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12431:     }else{
                   12432:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   12433:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  12434:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  12435:                }
1.201     brouard  12436:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  12437:                     stepm, weightopt,\
                   12438:                     model,imx,p,matcov,agemortsup);
                   12439:     
1.302     brouard  12440:     free_vector(lsurv,agegomp,AGESUP);
                   12441:     free_vector(lpop,agegomp,AGESUP);
                   12442:     free_vector(tpop,agegomp,AGESUP);
1.220     brouard  12443:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  12444:     free_ivector(dcwave,firstobs,lastobs);
                   12445:     free_vector(agecens,firstobs,lastobs);
                   12446:     free_vector(ageexmed,firstobs,lastobs);
                   12447:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  12448: #ifdef GSL
1.136     brouard  12449: #endif
1.186     brouard  12450:   } /* Endof if mle==-3 mortality only */
1.205     brouard  12451:   /* Standard  */
                   12452:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   12453:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12454:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  12455:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  12456:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12457:     for (k=1; k<=npar;k++)
                   12458:       printf(" %d %8.5f",k,p[k]);
                   12459:     printf("\n");
1.205     brouard  12460:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   12461:       /* mlikeli uses func not funcone */
1.247     brouard  12462:       /* for(i=1;i<nlstate;i++){ */
                   12463:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   12464:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   12465:       /* } */
1.205     brouard  12466:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   12467:     }
                   12468:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   12469:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12470:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   12471:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12472:     }
                   12473:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  12474:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12475:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12476:     for (k=1; k<=npar;k++)
                   12477:       printf(" %d %8.5f",k,p[k]);
                   12478:     printf("\n");
                   12479:     
                   12480:     /*--------- results files --------------*/
1.283     brouard  12481:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  12482:     
                   12483:     
                   12484:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
1.319     brouard  12485:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n"); /* Printing model equation */
1.126     brouard  12486:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
1.319     brouard  12487: 
                   12488:     printf("#model=  1      +     age ");
                   12489:     fprintf(ficres,"#model=  1      +     age ");
                   12490:     fprintf(ficlog,"#model=  1      +     age ");
                   12491:     fprintf(fichtm,"\n<ul><li> model=1+age+%s\n \
                   12492: </ul>", model);
                   12493: 
                   12494:     fprintf(fichtm,"\n<table style=\"text-align:center; border: 1px solid\">\n");
                   12495:     fprintf(fichtm, "<tr><th>Model=</th><th>1</th><th>+ age</th>");
                   12496:     if(nagesqr==1){
                   12497:       printf("  + age*age  ");
                   12498:       fprintf(ficres,"  + age*age  ");
                   12499:       fprintf(ficlog,"  + age*age  ");
                   12500:       fprintf(fichtm, "<th>+ age*age</th>");
                   12501:     }
                   12502:     for(j=1;j <=ncovmodel-2;j++){
                   12503:       if(Typevar[j]==0) {
                   12504:        printf("  +      V%d  ",Tvar[j]);
                   12505:        fprintf(ficres,"  +      V%d  ",Tvar[j]);
                   12506:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   12507:        fprintf(fichtm, "<th>+ V%d</th>",Tvar[j]);
                   12508:       }else if(Typevar[j]==1) {
                   12509:        printf("  +    V%d*age ",Tvar[j]);
                   12510:        fprintf(ficres,"  +    V%d*age ",Tvar[j]);
                   12511:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   12512:        fprintf(fichtm, "<th>+  V%d*age</th>",Tvar[j]);
                   12513:       }else if(Typevar[j]==2) {
                   12514:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12515:        fprintf(ficres,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12516:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12517:        fprintf(fichtm, "<th>+  V%d*V%d</th>",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12518:       }
                   12519:     }
                   12520:     printf("\n");
                   12521:     fprintf(ficres,"\n");
                   12522:     fprintf(ficlog,"\n");
                   12523:     fprintf(fichtm, "</tr>");
                   12524:     fprintf(fichtm, "\n");
                   12525:     
                   12526:     
1.126     brouard  12527:     for(i=1,jk=1; i <=nlstate; i++){
                   12528:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  12529:        if (k != i) {
1.319     brouard  12530:          fprintf(fichtm, "<tr>");
1.225     brouard  12531:          printf("%d%d ",i,k);
                   12532:          fprintf(ficlog,"%d%d ",i,k);
                   12533:          fprintf(ficres,"%1d%1d ",i,k);
1.319     brouard  12534:          fprintf(fichtm, "<td>%1d%1d</td>",i,k);
1.225     brouard  12535:          for(j=1; j <=ncovmodel; j++){
                   12536:            printf("%12.7f ",p[jk]);
                   12537:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12538:            fprintf(ficres,"%12.7f ",p[jk]);
1.319     brouard  12539:            fprintf(fichtm, "<td>%12.7f</td>",p[jk]);
1.225     brouard  12540:            jk++; 
                   12541:          }
                   12542:          printf("\n");
                   12543:          fprintf(ficlog,"\n");
                   12544:          fprintf(ficres,"\n");
1.319     brouard  12545:          fprintf(fichtm, "</tr>\n");
1.225     brouard  12546:        }
1.126     brouard  12547:       }
                   12548:     }
1.319     brouard  12549:     /* fprintf(fichtm,"</tr>\n"); */
                   12550:     fprintf(fichtm,"</table>\n");
                   12551:     fprintf(fichtm, "\n");
                   12552: 
1.203     brouard  12553:     if(mle != 0){
                   12554:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12555:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12556:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12557:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12558:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
1.322   ! brouard  12559:       fprintf(fichtm, "\n<p>The Wald test results are output only if the maximimzation of the Likelihood is performed (mle=1)\n</br>Parameters, Wald tests and Wald-based confidence intervals\n</br> W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n</br> And Wald-based confidence intervals plus and minus 1.96 * W \n </br> It might be better to visualize the covariance matrix. See the page '<a href=\"%s\">Matrix of variance-covariance of one-step probabilities and its graphs</a>'.\n</br>",optionfilehtmcov);
1.319     brouard  12560:       fprintf(fichtm,"\n<table style=\"text-align:center; border: 1px solid\">");
                   12561:       fprintf(fichtm, "\n<tr><th>Model=</th><th>1</th><th>+ age</th>");
                   12562:       if(nagesqr==1){
                   12563:        printf("  + age*age  ");
                   12564:        fprintf(ficres,"  + age*age  ");
                   12565:        fprintf(ficlog,"  + age*age  ");
                   12566:        fprintf(fichtm, "<th>+ age*age</th>");
                   12567:       }
                   12568:       for(j=1;j <=ncovmodel-2;j++){
                   12569:        if(Typevar[j]==0) {
                   12570:          printf("  +      V%d  ",Tvar[j]);
                   12571:          fprintf(fichtm, "<th>+ V%d</th>",Tvar[j]);
                   12572:        }else if(Typevar[j]==1) {
                   12573:          printf("  +    V%d*age ",Tvar[j]);
                   12574:          fprintf(fichtm, "<th>+  V%d*age</th>",Tvar[j]);
                   12575:        }else if(Typevar[j]==2) {
                   12576:          fprintf(fichtm, "<th>+  V%d*V%d</th>",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12577:        }
                   12578:       }
                   12579:       fprintf(fichtm, "</tr>\n");
                   12580:  
1.203     brouard  12581:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12582:        for(k=1; k <=(nlstate+ndeath); k++){
                   12583:          if (k != i) {
1.319     brouard  12584:            fprintf(fichtm, "<tr valign=top>");
1.225     brouard  12585:            printf("%d%d ",i,k);
                   12586:            fprintf(ficlog,"%d%d ",i,k);
1.319     brouard  12587:            fprintf(fichtm, "<td>%1d%1d</td>",i,k);
1.225     brouard  12588:            for(j=1; j <=ncovmodel; j++){
1.319     brouard  12589:              wald=p[jk]/sqrt(matcov[jk][jk]);
1.321     brouard  12590:              printf("%12.7f(%12.7f) sqrt(W)=%8.3f CI=[%12.7f ; %12.7f] ",p[jk],sqrt(matcov[jk][jk]), p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12591:              fprintf(ficlog,"%12.7f(%12.7f) sqrt(W)=%8.3f CI=[%12.7f ; %12.7f] ",p[jk],sqrt(matcov[jk][jk]), p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
1.319     brouard  12592:              if(fabs(wald) > 1.96){
1.321     brouard  12593:                fprintf(fichtm, "<td><b>%12.7f</b></br> (%12.7f)</br>",p[jk],sqrt(matcov[jk][jk]));
1.319     brouard  12594:              }else{
                   12595:                fprintf(fichtm, "<td>%12.7f (%12.7f)</br>",p[jk],sqrt(matcov[jk][jk]));
                   12596:              }
1.321     brouard  12597:              fprintf(fichtm,"sqrt(W)=%8.3f</br>",wald);
1.319     brouard  12598:              fprintf(fichtm,"[%12.7f;%12.7f]</br></td>", p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
1.225     brouard  12599:              jk++; 
                   12600:            }
                   12601:            printf("\n");
                   12602:            fprintf(ficlog,"\n");
1.319     brouard  12603:            fprintf(fichtm, "</tr>\n");
1.225     brouard  12604:          }
                   12605:        }
1.193     brouard  12606:       }
1.203     brouard  12607:     } /* end of hesscov and Wald tests */
1.319     brouard  12608:     fprintf(fichtm,"</table>\n");
1.225     brouard  12609:     
1.203     brouard  12610:     /*  */
1.126     brouard  12611:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12612:     printf("# Scales (for hessian or gradient estimation)\n");
                   12613:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12614:     for(i=1,jk=1; i <=nlstate; i++){
                   12615:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12616:        if (j!=i) {
                   12617:          fprintf(ficres,"%1d%1d",i,j);
                   12618:          printf("%1d%1d",i,j);
                   12619:          fprintf(ficlog,"%1d%1d",i,j);
                   12620:          for(k=1; k<=ncovmodel;k++){
                   12621:            printf(" %.5e",delti[jk]);
                   12622:            fprintf(ficlog," %.5e",delti[jk]);
                   12623:            fprintf(ficres," %.5e",delti[jk]);
                   12624:            jk++;
                   12625:          }
                   12626:          printf("\n");
                   12627:          fprintf(ficlog,"\n");
                   12628:          fprintf(ficres,"\n");
                   12629:        }
1.126     brouard  12630:       }
                   12631:     }
                   12632:     
                   12633:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12634:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12635:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12636:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12637:     /* # 121 Var(a12)\n\ */
                   12638:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12639:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12640:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12641:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12642:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12643:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12644:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12645:     
                   12646:     
                   12647:     /* Just to have a covariance matrix which will be more understandable
                   12648:        even is we still don't want to manage dictionary of variables
                   12649:     */
                   12650:     for(itimes=1;itimes<=2;itimes++){
                   12651:       jj=0;
                   12652:       for(i=1; i <=nlstate; i++){
1.225     brouard  12653:        for(j=1; j <=nlstate+ndeath; j++){
                   12654:          if(j==i) continue;
                   12655:          for(k=1; k<=ncovmodel;k++){
                   12656:            jj++;
                   12657:            ca[0]= k+'a'-1;ca[1]='\0';
                   12658:            if(itimes==1){
                   12659:              if(mle>=1)
                   12660:                printf("#%1d%1d%d",i,j,k);
                   12661:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12662:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12663:            }else{
                   12664:              if(mle>=1)
                   12665:                printf("%1d%1d%d",i,j,k);
                   12666:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12667:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12668:            }
                   12669:            ll=0;
                   12670:            for(li=1;li <=nlstate; li++){
                   12671:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12672:                if(lj==li) continue;
                   12673:                for(lk=1;lk<=ncovmodel;lk++){
                   12674:                  ll++;
                   12675:                  if(ll<=jj){
                   12676:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12677:                    if(ll<jj){
                   12678:                      if(itimes==1){
                   12679:                        if(mle>=1)
                   12680:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12681:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12682:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12683:                      }else{
                   12684:                        if(mle>=1)
                   12685:                          printf(" %.5e",matcov[jj][ll]); 
                   12686:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12687:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12688:                      }
                   12689:                    }else{
                   12690:                      if(itimes==1){
                   12691:                        if(mle>=1)
                   12692:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12693:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12694:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12695:                      }else{
                   12696:                        if(mle>=1)
                   12697:                          printf(" %.7e",matcov[jj][ll]); 
                   12698:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12699:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12700:                      }
                   12701:                    }
                   12702:                  }
                   12703:                } /* end lk */
                   12704:              } /* end lj */
                   12705:            } /* end li */
                   12706:            if(mle>=1)
                   12707:              printf("\n");
                   12708:            fprintf(ficlog,"\n");
                   12709:            fprintf(ficres,"\n");
                   12710:            numlinepar++;
                   12711:          } /* end k*/
                   12712:        } /*end j */
1.126     brouard  12713:       } /* end i */
                   12714:     } /* end itimes */
                   12715:     
                   12716:     fflush(ficlog);
                   12717:     fflush(ficres);
1.225     brouard  12718:     while(fgets(line, MAXLINE, ficpar)) {
                   12719:       /* If line starts with a # it is a comment */
                   12720:       if (line[0] == '#') {
                   12721:        numlinepar++;
                   12722:        fputs(line,stdout);
                   12723:        fputs(line,ficparo);
                   12724:        fputs(line,ficlog);
1.299     brouard  12725:        fputs(line,ficres);
1.225     brouard  12726:        continue;
                   12727:       }else
                   12728:        break;
                   12729:     }
                   12730:     
1.209     brouard  12731:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12732:     /*   ungetc(c,ficpar); */
                   12733:     /*   fgets(line, MAXLINE, ficpar); */
                   12734:     /*   fputs(line,stdout); */
                   12735:     /*   fputs(line,ficparo); */
                   12736:     /* } */
                   12737:     /* ungetc(c,ficpar); */
1.126     brouard  12738:     
                   12739:     estepm=0;
1.209     brouard  12740:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12741:       
                   12742:       if (num_filled != 6) {
                   12743:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12744:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12745:        goto end;
                   12746:       }
                   12747:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12748:     }
                   12749:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12750:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12751:     
1.209     brouard  12752:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12753:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12754:     if (fage <= 2) {
                   12755:       bage = ageminpar;
                   12756:       fage = agemaxpar;
                   12757:     }
                   12758:     
                   12759:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12760:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12761:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12762:                
1.186     brouard  12763:     /* Other stuffs, more or less useful */    
1.254     brouard  12764:     while(fgets(line, MAXLINE, ficpar)) {
                   12765:       /* If line starts with a # it is a comment */
                   12766:       if (line[0] == '#') {
                   12767:        numlinepar++;
                   12768:        fputs(line,stdout);
                   12769:        fputs(line,ficparo);
                   12770:        fputs(line,ficlog);
1.299     brouard  12771:        fputs(line,ficres);
1.254     brouard  12772:        continue;
                   12773:       }else
                   12774:        break;
                   12775:     }
                   12776: 
                   12777:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12778:       
                   12779:       if (num_filled != 7) {
                   12780:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12781:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12782:        goto end;
                   12783:       }
                   12784:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12785:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12786:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12787:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12788:     }
1.254     brouard  12789: 
                   12790:     while(fgets(line, MAXLINE, ficpar)) {
                   12791:       /* If line starts with a # it is a comment */
                   12792:       if (line[0] == '#') {
                   12793:        numlinepar++;
                   12794:        fputs(line,stdout);
                   12795:        fputs(line,ficparo);
                   12796:        fputs(line,ficlog);
1.299     brouard  12797:        fputs(line,ficres);
1.254     brouard  12798:        continue;
                   12799:       }else
                   12800:        break;
1.126     brouard  12801:     }
                   12802:     
                   12803:     
                   12804:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12805:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12806:     
1.254     brouard  12807:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12808:       if (num_filled != 1) {
                   12809:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12810:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12811:        goto end;
                   12812:       }
                   12813:       printf("pop_based=%d\n",popbased);
                   12814:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12815:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12816:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12817:     }
                   12818:      
1.258     brouard  12819:     /* Results */
1.307     brouard  12820:     endishere=0;
1.258     brouard  12821:     nresult=0;
1.308     brouard  12822:     parameterline=0;
1.258     brouard  12823:     do{
                   12824:       if(!fgets(line, MAXLINE, ficpar)){
                   12825:        endishere=1;
1.308     brouard  12826:        parameterline=15;
1.258     brouard  12827:       }else if (line[0] == '#') {
                   12828:        /* If line starts with a # it is a comment */
1.254     brouard  12829:        numlinepar++;
                   12830:        fputs(line,stdout);
                   12831:        fputs(line,ficparo);
                   12832:        fputs(line,ficlog);
1.299     brouard  12833:        fputs(line,ficres);
1.254     brouard  12834:        continue;
1.258     brouard  12835:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12836:        parameterline=11;
1.296     brouard  12837:       else if(sscanf(line,"prevbackcast=%[^\n]\n",modeltemp))
1.258     brouard  12838:        parameterline=12;
1.307     brouard  12839:       else if(sscanf(line,"result:%[^\n]\n",modeltemp)){
1.258     brouard  12840:        parameterline=13;
1.307     brouard  12841:       }
1.258     brouard  12842:       else{
                   12843:        parameterline=14;
1.254     brouard  12844:       }
1.308     brouard  12845:       switch (parameterline){ /* =0 only if only comments */
1.258     brouard  12846:       case 11:
1.296     brouard  12847:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12848:                  fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.258     brouard  12849:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12850:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12851:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12852:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12853:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12854:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
1.296     brouard  12855:           prvforecast = 1;
                   12856:        } 
                   12857:        else if((num_filled=sscanf(line,"prevforecast=%d yearsfproj=%lf mobil_average=%d\n",&prevfcast,&yrfproj,&mobilavproj)) !=EOF){/* && (num_filled == 3))*/
1.313     brouard  12858:          printf("prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12859:          fprintf(ficlog,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12860:          fprintf(ficres,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
1.296     brouard  12861:           prvforecast = 2;
                   12862:        }
                   12863:        else {
                   12864:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearsfproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12865:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12866:          goto end;
1.258     brouard  12867:        }
1.254     brouard  12868:        break;
1.258     brouard  12869:       case 12:
1.296     brouard  12870:        if((num_filled=sscanf(line,"prevbackcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&prevbcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12871:           fprintf(ficparo,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12872:          printf("prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12873:          fprintf(ficlog,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12874:          fprintf(ficres,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12875:          /* day and month of back2 are not used but only year anback2.*/
1.273     brouard  12876:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12877:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.296     brouard  12878:           prvbackcast = 1;
                   12879:        } 
                   12880:        else if((num_filled=sscanf(line,"prevbackcast=%d yearsbproj=%lf mobil_average=%d\n",&prevbcast,&yrbproj,&mobilavproj)) ==3){/* && (num_filled == 3))*/
1.313     brouard  12881:          printf("prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12882:          fprintf(ficlog,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12883:          fprintf(ficres,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
1.296     brouard  12884:           prvbackcast = 2;
                   12885:        }
                   12886:        else {
                   12887:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearsbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12888:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12889:          goto end;
1.258     brouard  12890:        }
1.230     brouard  12891:        break;
1.258     brouard  12892:       case 13:
1.307     brouard  12893:        num_filled=sscanf(line,"result:%[^\n]\n",resultline);
                   12894:        nresult++; /* Sum of resultlines */
                   12895:        printf("Result %d: result:%s\n",nresult, resultline);
1.318     brouard  12896:        if(nresult > MAXRESULTLINESPONE-1){
                   12897:          printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINESPONE-1,nresult,rfileres);
                   12898:          fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINESPONE-1,nresult,rfileres);
1.307     brouard  12899:          goto end;
                   12900:        }
1.310     brouard  12901:        if(!decoderesult(resultline, nresult)){ /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.314     brouard  12902:          fprintf(ficparo,"result: %s\n",resultline);
                   12903:          fprintf(ficres,"result: %s\n",resultline);
                   12904:          fprintf(ficlog,"result: %s\n",resultline);
1.310     brouard  12905:        } else
                   12906:          goto end;
1.307     brouard  12907:        break;
                   12908:       case 14:
                   12909:        printf("Error: Unknown command '%s'\n",line);
                   12910:        fprintf(ficlog,"Error: Unknown command '%s'\n",line);
1.314     brouard  12911:        if(line[0] == ' ' || line[0] == '\n'){
                   12912:          printf("It should not be an empty line '%s'\n",line);
                   12913:          fprintf(ficlog,"It should not be an empty line '%s'\n",line);
                   12914:        }         
1.307     brouard  12915:        if(ncovmodel >=2 && nresult==0 ){
                   12916:          printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
                   12917:          fprintf(ficlog,"ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12918:        }
1.307     brouard  12919:        /* goto end; */
                   12920:        break;
1.308     brouard  12921:       case 15:
                   12922:        printf("End of resultlines.\n");
                   12923:        fprintf(ficlog,"End of resultlines.\n");
                   12924:        break;
                   12925:       default: /* parameterline =0 */
1.307     brouard  12926:        nresult=1;
                   12927:        decoderesult(".",nresult ); /* No covariate */
1.258     brouard  12928:       } /* End switch parameterline */
                   12929:     }while(endishere==0); /* End do */
1.126     brouard  12930:     
1.230     brouard  12931:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12932:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12933:     
                   12934:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12935:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12936:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12937: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12938: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12939:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12940: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12941: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12942:     }else{
1.270     brouard  12943:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
1.296     brouard  12944:       /* It seems that anprojd which is computed from the mean year at interview which is known yet because of freqsummary */
                   12945:       /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */ /* Done in freqsummary */
                   12946:       if(prvforecast==1){
                   12947:         dateprojd=(jproj1+12*mproj1+365*anproj1)/365;
                   12948:         jprojd=jproj1;
                   12949:         mprojd=mproj1;
                   12950:         anprojd=anproj1;
                   12951:         dateprojf=(jproj2+12*mproj2+365*anproj2)/365;
                   12952:         jprojf=jproj2;
                   12953:         mprojf=mproj2;
                   12954:         anprojf=anproj2;
                   12955:       } else if(prvforecast == 2){
                   12956:         dateprojd=dateintmean;
                   12957:         date2dmy(dateprojd,&jprojd, &mprojd, &anprojd);
                   12958:         dateprojf=dateintmean+yrfproj;
                   12959:         date2dmy(dateprojf,&jprojf, &mprojf, &anprojf);
                   12960:       }
                   12961:       if(prvbackcast==1){
                   12962:         datebackd=(jback1+12*mback1+365*anback1)/365;
                   12963:         jbackd=jback1;
                   12964:         mbackd=mback1;
                   12965:         anbackd=anback1;
                   12966:         datebackf=(jback2+12*mback2+365*anback2)/365;
                   12967:         jbackf=jback2;
                   12968:         mbackf=mback2;
                   12969:         anbackf=anback2;
                   12970:       } else if(prvbackcast == 2){
                   12971:         datebackd=dateintmean;
                   12972:         date2dmy(datebackd,&jbackd, &mbackd, &anbackd);
                   12973:         datebackf=dateintmean-yrbproj;
                   12974:         date2dmy(datebackf,&jbackf, &mbackf, &anbackf);
                   12975:       }
                   12976:       
                   12977:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, prevbcast, pathc,p, (int)anprojd-bage, (int)anbackd-fage);
1.220     brouard  12978:     }
                   12979:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.296     brouard  12980:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,prevbcast, estepm, \
                   12981:                 jprev1,mprev1,anprev1,dateprev1, dateprojd, datebackd,jprev2,mprev2,anprev2,dateprev2,dateprojf, datebackf);
1.220     brouard  12982:                
1.225     brouard  12983:     /*------------ free_vector  -------------*/
                   12984:     /*  chdir(path); */
1.220     brouard  12985:                
1.215     brouard  12986:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12987:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12988:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12989:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  12990:     free_lvector(num,firstobs,lastobs);
                   12991:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  12992:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12993:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12994:     fclose(ficparo);
                   12995:     fclose(ficres);
1.220     brouard  12996:                
                   12997:                
1.186     brouard  12998:     /* Other results (useful)*/
1.220     brouard  12999:                
                   13000:                
1.126     brouard  13001:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  13002:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   13003:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  13004:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  13005:     fclose(ficrespl);
                   13006: 
                   13007:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  13008:     /*#include "hpijx.h"*/
                   13009:     hPijx(p, bage, fage);
1.145     brouard  13010:     fclose(ficrespij);
1.227     brouard  13011:     
1.220     brouard  13012:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  13013:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  13014:     k=1;
1.126     brouard  13015:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  13016:     
1.269     brouard  13017:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   13018:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   13019:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  13020:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  13021:        for(k=1;k<=ncovcombmax;k++)
                   13022:          probs[i][j][k]=0.;
1.269     brouard  13023:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   13024:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  13025:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  13026:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   13027:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  13028:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  13029:          for(k=1;k<=ncovcombmax;k++)
                   13030:            mobaverages[i][j][k]=0.;
1.219     brouard  13031:       mobaverage=mobaverages;
                   13032:       if (mobilav!=0) {
1.235     brouard  13033:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  13034:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  13035:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   13036:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   13037:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   13038:        }
1.269     brouard  13039:       } else if (mobilavproj !=0) {
1.235     brouard  13040:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  13041:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  13042:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   13043:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   13044:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   13045:        }
1.269     brouard  13046:       }else{
                   13047:        printf("Internal error moving average\n");
                   13048:        fflush(stdout);
                   13049:        exit(1);
1.219     brouard  13050:       }
                   13051:     }/* end if moving average */
1.227     brouard  13052:     
1.126     brouard  13053:     /*---------- Forecasting ------------------*/
1.296     brouard  13054:     if(prevfcast==1){ 
                   13055:       /*   /\*    if(stepm ==1){*\/ */
                   13056:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   13057:       /*This done previously after freqsummary.*/
                   13058:       /*   dateprojd=(jproj1+12*mproj1+365*anproj1)/365; */
                   13059:       /*   dateprojf=(jproj2+12*mproj2+365*anproj2)/365; */
                   13060:       
                   13061:       /* } else if (prvforecast==2){ */
                   13062:       /*   /\*    if(stepm ==1){*\/ */
                   13063:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   13064:       /* } */
                   13065:       /*prevforecast(fileresu, dateintmean, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);*/
                   13066:       prevforecast(fileresu,dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, p, cptcoveff);
1.126     brouard  13067:     }
1.269     brouard  13068: 
1.296     brouard  13069:     /* Prevbcasting */
                   13070:     if(prevbcast==1){
1.219     brouard  13071:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   13072:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   13073:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   13074: 
                   13075:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   13076: 
                   13077:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  13078: 
1.219     brouard  13079:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   13080:       fclose(ficresplb);
                   13081: 
1.222     brouard  13082:       hBijx(p, bage, fage, mobaverage);
                   13083:       fclose(ficrespijb);
1.219     brouard  13084: 
1.296     brouard  13085:       /* /\* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, *\/ */
                   13086:       /* /\*                  mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); *\/ */
                   13087:       /* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, */
                   13088:       /*                      mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
                   13089:       prevbackforecast(fileresu, mobaverage, dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2,
                   13090:                       mobilavproj, bage, fage, firstpass, lastpass, p, cptcoveff);
                   13091: 
                   13092:       
1.269     brouard  13093:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  13094: 
                   13095:       
1.269     brouard  13096:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  13097:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   13098:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   13099:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.296     brouard  13100:     }    /* end  Prevbcasting */
1.268     brouard  13101:  
1.186     brouard  13102:  
                   13103:     /* ------ Other prevalence ratios------------ */
1.126     brouard  13104: 
1.215     brouard  13105:     free_ivector(wav,1,imx);
                   13106:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   13107:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   13108:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  13109:                
                   13110:                
1.127     brouard  13111:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  13112:                
1.201     brouard  13113:     strcpy(filerese,"E_");
                   13114:     strcat(filerese,fileresu);
1.126     brouard  13115:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   13116:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   13117:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   13118:     }
1.208     brouard  13119:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   13120:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  13121: 
                   13122:     pstamp(ficreseij);
1.219     brouard  13123:                
1.235     brouard  13124:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   13125:     if (cptcovn < 1){i1=1;}
                   13126:     
                   13127:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   13128:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  13129:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  13130:        continue;
1.219     brouard  13131:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  13132:       printf("\n#****** ");
1.225     brouard  13133:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  13134:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  13135:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13136:       }
                   13137:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13138:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13139:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  13140:       }
                   13141:       fprintf(ficreseij,"******\n");
1.235     brouard  13142:       printf("******\n");
1.219     brouard  13143:       
                   13144:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   13145:       oldm=oldms;savm=savms;
1.235     brouard  13146:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  13147:       
1.219     brouard  13148:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  13149:     }
                   13150:     fclose(ficreseij);
1.208     brouard  13151:     printf("done evsij\n");fflush(stdout);
                   13152:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  13153: 
1.218     brouard  13154:                
1.227     brouard  13155:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  13156:                
1.201     brouard  13157:     strcpy(filerest,"T_");
                   13158:     strcat(filerest,fileresu);
1.127     brouard  13159:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   13160:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   13161:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   13162:     }
1.208     brouard  13163:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   13164:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  13165:     strcpy(fileresstde,"STDE_");
                   13166:     strcat(fileresstde,fileresu);
1.126     brouard  13167:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  13168:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   13169:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  13170:     }
1.227     brouard  13171:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   13172:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  13173: 
1.201     brouard  13174:     strcpy(filerescve,"CVE_");
                   13175:     strcat(filerescve,fileresu);
1.126     brouard  13176:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  13177:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   13178:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  13179:     }
1.227     brouard  13180:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   13181:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  13182: 
1.201     brouard  13183:     strcpy(fileresv,"V_");
                   13184:     strcat(fileresv,fileresu);
1.126     brouard  13185:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   13186:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   13187:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   13188:     }
1.227     brouard  13189:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   13190:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  13191: 
1.235     brouard  13192:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   13193:     if (cptcovn < 1){i1=1;}
                   13194:     
                   13195:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   13196:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  13197:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  13198:        continue;
1.321     brouard  13199:       printf("\n# model %s \n#****** Result for:", model);
                   13200:       fprintf(ficrest,"\n# model %s \n#****** Result for:", model);
                   13201:       fprintf(ficlog,"\n# model %s \n#****** Result for:", model);
1.227     brouard  13202:       for(j=1;j<=cptcoveff;j++){ 
                   13203:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13204:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13205:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13206:       }
1.235     brouard  13207:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13208:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13209:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13210:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13211:       }        
1.208     brouard  13212:       fprintf(ficrest,"******\n");
1.227     brouard  13213:       fprintf(ficlog,"******\n");
                   13214:       printf("******\n");
1.208     brouard  13215:       
                   13216:       fprintf(ficresstdeij,"\n#****** ");
                   13217:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  13218:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  13219:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13220:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  13221:       }
1.235     brouard  13222:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13223:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13224:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13225:       }        
1.208     brouard  13226:       fprintf(ficresstdeij,"******\n");
                   13227:       fprintf(ficrescveij,"******\n");
                   13228:       
                   13229:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  13230:       /* pstamp(ficresvij); */
1.225     brouard  13231:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  13232:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  13233:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13234:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13235:       }        
1.208     brouard  13236:       fprintf(ficresvij,"******\n");
                   13237:       
                   13238:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   13239:       oldm=oldms;savm=savms;
1.235     brouard  13240:       printf(" cvevsij ");
                   13241:       fprintf(ficlog, " cvevsij ");
                   13242:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  13243:       printf(" end cvevsij \n ");
                   13244:       fprintf(ficlog, " end cvevsij \n ");
                   13245:       
                   13246:       /*
                   13247:        */
                   13248:       /* goto endfree; */
                   13249:       
                   13250:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   13251:       pstamp(ficrest);
                   13252:       
1.269     brouard  13253:       epj=vector(1,nlstate+1);
1.208     brouard  13254:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  13255:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   13256:        cptcod= 0; /* To be deleted */
                   13257:        printf("varevsij vpopbased=%d \n",vpopbased);
                   13258:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  13259:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  13260:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   13261:        if(vpopbased==1)
                   13262:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   13263:        else
1.288     brouard  13264:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  13265:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   13266:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   13267:        fprintf(ficrest,"\n");
                   13268:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  13269:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   13270:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  13271:        for(age=bage; age <=fage ;age++){
1.235     brouard  13272:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  13273:          if (vpopbased==1) {
                   13274:            if(mobilav ==0){
                   13275:              for(i=1; i<=nlstate;i++)
                   13276:                prlim[i][i]=probs[(int)age][i][k];
                   13277:            }else{ /* mobilav */ 
                   13278:              for(i=1; i<=nlstate;i++)
                   13279:                prlim[i][i]=mobaverage[(int)age][i][k];
                   13280:            }
                   13281:          }
1.219     brouard  13282:          
1.227     brouard  13283:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   13284:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   13285:          /* printf(" age %4.0f ",age); */
                   13286:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   13287:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   13288:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   13289:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   13290:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   13291:            }
                   13292:            epj[nlstate+1] +=epj[j];
                   13293:          }
                   13294:          /* printf(" age %4.0f \n",age); */
1.219     brouard  13295:          
1.227     brouard  13296:          for(i=1, vepp=0.;i <=nlstate;i++)
                   13297:            for(j=1;j <=nlstate;j++)
                   13298:              vepp += vareij[i][j][(int)age];
                   13299:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   13300:          for(j=1;j <=nlstate;j++){
                   13301:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   13302:          }
                   13303:          fprintf(ficrest,"\n");
                   13304:        }
1.208     brouard  13305:       } /* End vpopbased */
1.269     brouard  13306:       free_vector(epj,1,nlstate+1);
1.208     brouard  13307:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   13308:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  13309:       printf("done selection\n");fflush(stdout);
                   13310:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  13311:       
1.235     brouard  13312:     } /* End k selection */
1.227     brouard  13313: 
                   13314:     printf("done State-specific expectancies\n");fflush(stdout);
                   13315:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   13316: 
1.288     brouard  13317:     /* variance-covariance of forward period prevalence*/
1.269     brouard  13318:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  13319: 
1.227     brouard  13320:     
1.290     brouard  13321:     free_vector(weight,firstobs,lastobs);
1.227     brouard  13322:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  13323:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   13324:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   13325:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   13326:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  13327:     free_ivector(tab,1,NCOVMAX);
                   13328:     fclose(ficresstdeij);
                   13329:     fclose(ficrescveij);
                   13330:     fclose(ficresvij);
                   13331:     fclose(ficrest);
                   13332:     fclose(ficpar);
                   13333:     
                   13334:     
1.126     brouard  13335:     /*---------- End : free ----------------*/
1.219     brouard  13336:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  13337:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   13338:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  13339:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   13340:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  13341:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  13342:   /* endfree:*/
                   13343:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   13344:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   13345:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  13346:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   13347:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   13348:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   13349:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  13350:   free_matrix(matcov,1,npar,1,npar);
                   13351:   free_matrix(hess,1,npar,1,npar);
                   13352:   /*free_vector(delti,1,npar);*/
                   13353:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   13354:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  13355:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  13356:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   13357:   
                   13358:   free_ivector(ncodemax,1,NCOVMAX);
                   13359:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   13360:   free_ivector(Dummy,-1,NCOVMAX);
                   13361:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  13362:   free_ivector(DummyV,1,NCOVMAX);
                   13363:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  13364:   free_ivector(Typevar,-1,NCOVMAX);
                   13365:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  13366:   free_ivector(TvarsQ,1,NCOVMAX);
                   13367:   free_ivector(TvarsQind,1,NCOVMAX);
                   13368:   free_ivector(TvarsD,1,NCOVMAX);
                   13369:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  13370:   free_ivector(TvarFD,1,NCOVMAX);
                   13371:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  13372:   free_ivector(TvarF,1,NCOVMAX);
                   13373:   free_ivector(TvarFind,1,NCOVMAX);
                   13374:   free_ivector(TvarV,1,NCOVMAX);
                   13375:   free_ivector(TvarVind,1,NCOVMAX);
                   13376:   free_ivector(TvarA,1,NCOVMAX);
                   13377:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  13378:   free_ivector(TvarFQ,1,NCOVMAX);
                   13379:   free_ivector(TvarFQind,1,NCOVMAX);
                   13380:   free_ivector(TvarVD,1,NCOVMAX);
                   13381:   free_ivector(TvarVDind,1,NCOVMAX);
                   13382:   free_ivector(TvarVQ,1,NCOVMAX);
                   13383:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  13384:   free_ivector(Tvarsel,1,NCOVMAX);
                   13385:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  13386:   free_ivector(Tposprod,1,NCOVMAX);
                   13387:   free_ivector(Tprod,1,NCOVMAX);
                   13388:   free_ivector(Tvaraff,1,NCOVMAX);
                   13389:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   13390:   free_ivector(Tage,1,NCOVMAX);
                   13391:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  13392:   free_ivector(TmodelInvind,1,NCOVMAX);
                   13393:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  13394:   
                   13395:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   13396:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  13397:   fflush(fichtm);
                   13398:   fflush(ficgp);
                   13399:   
1.227     brouard  13400:   
1.126     brouard  13401:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  13402:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   13403:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  13404:   }else{
                   13405:     printf("End of Imach\n");
                   13406:     fprintf(ficlog,"End of Imach\n");
                   13407:   }
                   13408:   printf("See log file on %s\n",filelog);
                   13409:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  13410:   /*(void) gettimeofday(&end_time,&tzp);*/
                   13411:   rend_time = time(NULL);  
                   13412:   end_time = *localtime(&rend_time);
                   13413:   /* tml = *localtime(&end_time.tm_sec); */
                   13414:   strcpy(strtend,asctime(&end_time));
1.126     brouard  13415:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   13416:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  13417:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  13418:   
1.157     brouard  13419:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   13420:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   13421:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  13422:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   13423: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   13424:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13425:   fclose(fichtm);
                   13426:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13427:   fclose(fichtmcov);
                   13428:   fclose(ficgp);
                   13429:   fclose(ficlog);
                   13430:   /*------ End -----------*/
1.227     brouard  13431:   
1.281     brouard  13432: 
                   13433: /* Executes gnuplot */
1.227     brouard  13434:   
                   13435:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  13436: #ifdef WIN32
1.227     brouard  13437:   if (_chdir(pathcd) != 0)
                   13438:     printf("Can't move to directory %s!\n",path);
                   13439:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  13440: #else
1.227     brouard  13441:     if(chdir(pathcd) != 0)
                   13442:       printf("Can't move to directory %s!\n", path);
                   13443:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  13444: #endif 
1.126     brouard  13445:     printf("Current directory %s!\n",pathcd);
                   13446:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   13447:   sprintf(plotcmd,"gnuplot");
1.157     brouard  13448: #ifdef _WIN32
1.126     brouard  13449:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   13450: #endif
                   13451:   if(!stat(plotcmd,&info)){
1.158     brouard  13452:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13453:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  13454:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  13455:     }else
                   13456:       strcpy(pplotcmd,plotcmd);
1.157     brouard  13457: #ifdef __unix
1.126     brouard  13458:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   13459:     if(!stat(plotcmd,&info)){
1.158     brouard  13460:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13461:     }else
                   13462:       strcpy(pplotcmd,plotcmd);
                   13463: #endif
                   13464:   }else
                   13465:     strcpy(pplotcmd,plotcmd);
                   13466:   
                   13467:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  13468:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.292     brouard  13469:   strcpy(pplotcmd,plotcmd);
1.227     brouard  13470:   
1.126     brouard  13471:   if((outcmd=system(plotcmd)) != 0){
1.292     brouard  13472:     printf("Error in gnuplot, command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  13473:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  13474:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.292     brouard  13475:     if((outcmd=system(plotcmd)) != 0){
1.153     brouard  13476:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.292     brouard  13477:       strcpy(plotcmd,pplotcmd);
                   13478:     }
1.126     brouard  13479:   }
1.158     brouard  13480:   printf(" Successful, please wait...");
1.126     brouard  13481:   while (z[0] != 'q') {
                   13482:     /* chdir(path); */
1.154     brouard  13483:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  13484:     scanf("%s",z);
                   13485: /*     if (z[0] == 'c') system("./imach"); */
                   13486:     if (z[0] == 'e') {
1.158     brouard  13487: #ifdef __APPLE__
1.152     brouard  13488:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  13489: #elif __linux
                   13490:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  13491: #else
1.152     brouard  13492:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  13493: #endif
                   13494:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   13495:       system(pplotcmd);
1.126     brouard  13496:     }
                   13497:     else if (z[0] == 'g') system(plotcmd);
                   13498:     else if (z[0] == 'q') exit(0);
                   13499:   }
1.227     brouard  13500: end:
1.126     brouard  13501:   while (z[0] != 'q') {
1.195     brouard  13502:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  13503:     scanf("%s",z);
                   13504:   }
1.283     brouard  13505:   printf("End\n");
1.282     brouard  13506:   exit(0);
1.126     brouard  13507: }

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