Annotation of imach/src/imach.c, revision 1.323

1.323   ! brouard     1: /* $Id: imach.c,v 1.322 2022/07/22 12:27:48 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.323   ! brouard     4:   Revision 1.322  2022/07/22 12:27:48  brouard
        !             5:   *  imach.c (Module): Output of Wald test in the htm file and not only in the log.
        !             6: 
1.322     brouard     7:   Revision 1.321  2022/07/22 12:04:24  brouard
                      8:   Summary: r28
                      9: 
                     10:   *  imach.c (Module): Output of Wald test in the htm file and not only in the log.
                     11: 
1.321     brouard    12:   Revision 1.320  2022/06/02 05:10:11  brouard
                     13:   *** empty log message ***
                     14: 
1.320     brouard    15:   Revision 1.319  2022/06/02 04:45:11  brouard
                     16:   * imach.c (Module): Adding the Wald tests from the log to the main
                     17:   htm for better display of the maximum likelihood estimators.
                     18: 
1.319     brouard    19:   Revision 1.318  2022/05/24 08:10:59  brouard
                     20:   * imach.c (Module): Some attempts to find a bug of wrong estimates
                     21:   of confidencce intervals with product in the equation modelC
                     22: 
1.318     brouard    23:   Revision 1.317  2022/05/15 15:06:23  brouard
                     24:   * imach.c (Module):  Some minor improvements
                     25: 
1.317     brouard    26:   Revision 1.316  2022/05/11 15:11:31  brouard
                     27:   Summary: r27
                     28: 
1.316     brouard    29:   Revision 1.315  2022/05/11 15:06:32  brouard
                     30:   *** empty log message ***
                     31: 
1.315     brouard    32:   Revision 1.314  2022/04/13 17:43:09  brouard
                     33:   * imach.c (Module): Adding link to text data files
                     34: 
1.314     brouard    35:   Revision 1.313  2022/04/11 15:57:42  brouard
                     36:   * imach.c (Module): Error in rewriting the 'r' file with yearsfproj or yearsbproj fixed
                     37: 
1.313     brouard    38:   Revision 1.312  2022/04/05 21:24:39  brouard
                     39:   *** empty log message ***
                     40: 
1.312     brouard    41:   Revision 1.311  2022/04/05 21:03:51  brouard
                     42:   Summary: Fixed quantitative covariates
                     43: 
                     44:          Fixed covariates (dummy or quantitative)
                     45:        with missing values have never been allowed but are ERRORS and
                     46:        program quits. Standard deviations of fixed covariates were
                     47:        wrongly computed. Mean and standard deviations of time varying
                     48:        covariates are still not computed.
                     49: 
1.311     brouard    50:   Revision 1.310  2022/03/17 08:45:53  brouard
                     51:   Summary: 99r25
                     52: 
                     53:   Improving detection of errors: result lines should be compatible with
                     54:   the model.
                     55: 
1.310     brouard    56:   Revision 1.309  2021/05/20 12:39:14  brouard
                     57:   Summary: Version 0.99r24
                     58: 
1.309     brouard    59:   Revision 1.308  2021/03/31 13:11:57  brouard
                     60:   Summary: Version 0.99r23
                     61: 
                     62: 
                     63:   * imach.c (Module): Still bugs in the result loop. Thank to Holly Benett
                     64: 
1.308     brouard    65:   Revision 1.307  2021/03/08 18:11:32  brouard
                     66:   Summary: 0.99r22 fixed bug on result:
                     67: 
1.307     brouard    68:   Revision 1.306  2021/02/20 15:44:02  brouard
                     69:   Summary: Version 0.99r21
                     70: 
                     71:   * imach.c (Module): Fix bug on quitting after result lines!
                     72:   (Module): Version 0.99r21
                     73: 
1.306     brouard    74:   Revision 1.305  2021/02/20 15:28:30  brouard
                     75:   * imach.c (Module): Fix bug on quitting after result lines!
                     76: 
1.305     brouard    77:   Revision 1.304  2021/02/12 11:34:20  brouard
                     78:   * imach.c (Module): The use of a Windows BOM (huge) file is now an error
                     79: 
1.304     brouard    80:   Revision 1.303  2021/02/11 19:50:15  brouard
                     81:   *  (Module): imach.c Someone entered 'results:' instead of 'result:'. Now it is an error which is printed.
                     82: 
1.303     brouard    83:   Revision 1.302  2020/02/22 21:00:05  brouard
                     84:   *  (Module): imach.c Update mle=-3 (for computing Life expectancy
                     85:   and life table from the data without any state)
                     86: 
1.302     brouard    87:   Revision 1.301  2019/06/04 13:51:20  brouard
                     88:   Summary: Error in 'r'parameter file backcast yearsbproj instead of yearsfproj
                     89: 
1.301     brouard    90:   Revision 1.300  2019/05/22 19:09:45  brouard
                     91:   Summary: version 0.99r19 of May 2019
                     92: 
1.300     brouard    93:   Revision 1.299  2019/05/22 18:37:08  brouard
                     94:   Summary: Cleaned 0.99r19
                     95: 
1.299     brouard    96:   Revision 1.298  2019/05/22 18:19:56  brouard
                     97:   *** empty log message ***
                     98: 
1.298     brouard    99:   Revision 1.297  2019/05/22 17:56:10  brouard
                    100:   Summary: Fix bug by moving date2dmy and nhstepm which gaefin=-1
                    101: 
1.297     brouard   102:   Revision 1.296  2019/05/20 13:03:18  brouard
                    103:   Summary: Projection syntax simplified
                    104: 
                    105: 
                    106:   We can now start projections, forward or backward, from the mean date
                    107:   of inteviews up to or down to a number of years of projection:
                    108:   prevforecast=1 yearsfproj=15.3 mobil_average=0
                    109:   or
                    110:   prevforecast=1 starting-proj-date=1/1/2007 final-proj-date=12/31/2017 mobil_average=0
                    111:   or
                    112:   prevbackcast=1 yearsbproj=12.3 mobil_average=1
                    113:   or
                    114:   prevbackcast=1 starting-back-date=1/10/1999 final-back-date=1/1/1985 mobil_average=1
                    115: 
1.296     brouard   116:   Revision 1.295  2019/05/18 09:52:50  brouard
                    117:   Summary: doxygen tex bug
                    118: 
1.295     brouard   119:   Revision 1.294  2019/05/16 14:54:33  brouard
                    120:   Summary: There was some wrong lines added
                    121: 
1.294     brouard   122:   Revision 1.293  2019/05/09 15:17:34  brouard
                    123:   *** empty log message ***
                    124: 
1.293     brouard   125:   Revision 1.292  2019/05/09 14:17:20  brouard
                    126:   Summary: Some updates
                    127: 
1.292     brouard   128:   Revision 1.291  2019/05/09 13:44:18  brouard
                    129:   Summary: Before ncovmax
                    130: 
1.291     brouard   131:   Revision 1.290  2019/05/09 13:39:37  brouard
                    132:   Summary: 0.99r18 unlimited number of individuals
                    133: 
                    134:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
                    135: 
1.290     brouard   136:   Revision 1.289  2018/12/13 09:16:26  brouard
                    137:   Summary: Bug for young ages (<-30) will be in r17
                    138: 
1.289     brouard   139:   Revision 1.288  2018/05/02 20:58:27  brouard
                    140:   Summary: Some bugs fixed
                    141: 
1.288     brouard   142:   Revision 1.287  2018/05/01 17:57:25  brouard
                    143:   Summary: Bug fixed by providing frequencies only for non missing covariates
                    144: 
1.287     brouard   145:   Revision 1.286  2018/04/27 14:27:04  brouard
                    146:   Summary: some minor bugs
                    147: 
1.286     brouard   148:   Revision 1.285  2018/04/21 21:02:16  brouard
                    149:   Summary: Some bugs fixed, valgrind tested
                    150: 
1.285     brouard   151:   Revision 1.284  2018/04/20 05:22:13  brouard
                    152:   Summary: Computing mean and stdeviation of fixed quantitative variables
                    153: 
1.284     brouard   154:   Revision 1.283  2018/04/19 14:49:16  brouard
                    155:   Summary: Some minor bugs fixed
                    156: 
1.283     brouard   157:   Revision 1.282  2018/02/27 22:50:02  brouard
                    158:   *** empty log message ***
                    159: 
1.282     brouard   160:   Revision 1.281  2018/02/27 19:25:23  brouard
                    161:   Summary: Adding second argument for quitting
                    162: 
1.281     brouard   163:   Revision 1.280  2018/02/21 07:58:13  brouard
                    164:   Summary: 0.99r15
                    165: 
                    166:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                    167: 
1.280     brouard   168:   Revision 1.279  2017/07/20 13:35:01  brouard
                    169:   Summary: temporary working
                    170: 
1.279     brouard   171:   Revision 1.278  2017/07/19 14:09:02  brouard
                    172:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                    173: 
1.278     brouard   174:   Revision 1.277  2017/07/17 08:53:49  brouard
                    175:   Summary: BOM files can be read now
                    176: 
1.277     brouard   177:   Revision 1.276  2017/06/30 15:48:31  brouard
                    178:   Summary: Graphs improvements
                    179: 
1.276     brouard   180:   Revision 1.275  2017/06/30 13:39:33  brouard
                    181:   Summary: Saito's color
                    182: 
1.275     brouard   183:   Revision 1.274  2017/06/29 09:47:08  brouard
                    184:   Summary: Version 0.99r14
                    185: 
1.274     brouard   186:   Revision 1.273  2017/06/27 11:06:02  brouard
                    187:   Summary: More documentation on projections
                    188: 
1.273     brouard   189:   Revision 1.272  2017/06/27 10:22:40  brouard
                    190:   Summary: Color of backprojection changed from 6 to 5(yellow)
                    191: 
1.272     brouard   192:   Revision 1.271  2017/06/27 10:17:50  brouard
                    193:   Summary: Some bug with rint
                    194: 
1.271     brouard   195:   Revision 1.270  2017/05/24 05:45:29  brouard
                    196:   *** empty log message ***
                    197: 
1.270     brouard   198:   Revision 1.269  2017/05/23 08:39:25  brouard
                    199:   Summary: Code into subroutine, cleanings
                    200: 
1.269     brouard   201:   Revision 1.268  2017/05/18 20:09:32  brouard
                    202:   Summary: backprojection and confidence intervals of backprevalence
                    203: 
1.268     brouard   204:   Revision 1.267  2017/05/13 10:25:05  brouard
                    205:   Summary: temporary save for backprojection
                    206: 
1.267     brouard   207:   Revision 1.266  2017/05/13 07:26:12  brouard
                    208:   Summary: Version 0.99r13 (improvements and bugs fixed)
                    209: 
1.266     brouard   210:   Revision 1.265  2017/04/26 16:22:11  brouard
                    211:   Summary: imach 0.99r13 Some bugs fixed
                    212: 
1.265     brouard   213:   Revision 1.264  2017/04/26 06:01:29  brouard
                    214:   Summary: Labels in graphs
                    215: 
1.264     brouard   216:   Revision 1.263  2017/04/24 15:23:15  brouard
                    217:   Summary: to save
                    218: 
1.263     brouard   219:   Revision 1.262  2017/04/18 16:48:12  brouard
                    220:   *** empty log message ***
                    221: 
1.262     brouard   222:   Revision 1.261  2017/04/05 10:14:09  brouard
                    223:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                    224: 
1.261     brouard   225:   Revision 1.260  2017/04/04 17:46:59  brouard
                    226:   Summary: Gnuplot indexations fixed (humm)
                    227: 
1.260     brouard   228:   Revision 1.259  2017/04/04 13:01:16  brouard
                    229:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    230: 
1.259     brouard   231:   Revision 1.258  2017/04/03 10:17:47  brouard
                    232:   Summary: Version 0.99r12
                    233: 
                    234:   Some cleanings, conformed with updated documentation.
                    235: 
1.258     brouard   236:   Revision 1.257  2017/03/29 16:53:30  brouard
                    237:   Summary: Temp
                    238: 
1.257     brouard   239:   Revision 1.256  2017/03/27 05:50:23  brouard
                    240:   Summary: Temporary
                    241: 
1.256     brouard   242:   Revision 1.255  2017/03/08 16:02:28  brouard
                    243:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    244: 
1.255     brouard   245:   Revision 1.254  2017/03/08 07:13:00  brouard
                    246:   Summary: Fixing data parameter line
                    247: 
1.254     brouard   248:   Revision 1.253  2016/12/15 11:59:41  brouard
                    249:   Summary: 0.99 in progress
                    250: 
1.253     brouard   251:   Revision 1.252  2016/09/15 21:15:37  brouard
                    252:   *** empty log message ***
                    253: 
1.252     brouard   254:   Revision 1.251  2016/09/15 15:01:13  brouard
                    255:   Summary: not working
                    256: 
1.251     brouard   257:   Revision 1.250  2016/09/08 16:07:27  brouard
                    258:   Summary: continue
                    259: 
1.250     brouard   260:   Revision 1.249  2016/09/07 17:14:18  brouard
                    261:   Summary: Starting values from frequencies
                    262: 
1.249     brouard   263:   Revision 1.248  2016/09/07 14:10:18  brouard
                    264:   *** empty log message ***
                    265: 
1.248     brouard   266:   Revision 1.247  2016/09/02 11:11:21  brouard
                    267:   *** empty log message ***
                    268: 
1.247     brouard   269:   Revision 1.246  2016/09/02 08:49:22  brouard
                    270:   *** empty log message ***
                    271: 
1.246     brouard   272:   Revision 1.245  2016/09/02 07:25:01  brouard
                    273:   *** empty log message ***
                    274: 
1.245     brouard   275:   Revision 1.244  2016/09/02 07:17:34  brouard
                    276:   *** empty log message ***
                    277: 
1.244     brouard   278:   Revision 1.243  2016/09/02 06:45:35  brouard
                    279:   *** empty log message ***
                    280: 
1.243     brouard   281:   Revision 1.242  2016/08/30 15:01:20  brouard
                    282:   Summary: Fixing a lots
                    283: 
1.242     brouard   284:   Revision 1.241  2016/08/29 17:17:25  brouard
                    285:   Summary: gnuplot problem in Back projection to fix
                    286: 
1.241     brouard   287:   Revision 1.240  2016/08/29 07:53:18  brouard
                    288:   Summary: Better
                    289: 
1.240     brouard   290:   Revision 1.239  2016/08/26 15:51:03  brouard
                    291:   Summary: Improvement in Powell output in order to copy and paste
                    292: 
                    293:   Author:
                    294: 
1.239     brouard   295:   Revision 1.238  2016/08/26 14:23:35  brouard
                    296:   Summary: Starting tests of 0.99
                    297: 
1.238     brouard   298:   Revision 1.237  2016/08/26 09:20:19  brouard
                    299:   Summary: to valgrind
                    300: 
1.237     brouard   301:   Revision 1.236  2016/08/25 10:50:18  brouard
                    302:   *** empty log message ***
                    303: 
1.236     brouard   304:   Revision 1.235  2016/08/25 06:59:23  brouard
                    305:   *** empty log message ***
                    306: 
1.235     brouard   307:   Revision 1.234  2016/08/23 16:51:20  brouard
                    308:   *** empty log message ***
                    309: 
1.234     brouard   310:   Revision 1.233  2016/08/23 07:40:50  brouard
                    311:   Summary: not working
                    312: 
1.233     brouard   313:   Revision 1.232  2016/08/22 14:20:21  brouard
                    314:   Summary: not working
                    315: 
1.232     brouard   316:   Revision 1.231  2016/08/22 07:17:15  brouard
                    317:   Summary: not working
                    318: 
1.231     brouard   319:   Revision 1.230  2016/08/22 06:55:53  brouard
                    320:   Summary: Not working
                    321: 
1.230     brouard   322:   Revision 1.229  2016/07/23 09:45:53  brouard
                    323:   Summary: Completing for func too
                    324: 
1.229     brouard   325:   Revision 1.228  2016/07/22 17:45:30  brouard
                    326:   Summary: Fixing some arrays, still debugging
                    327: 
1.227     brouard   328:   Revision 1.226  2016/07/12 18:42:34  brouard
                    329:   Summary: temp
                    330: 
1.226     brouard   331:   Revision 1.225  2016/07/12 08:40:03  brouard
                    332:   Summary: saving but not running
                    333: 
1.225     brouard   334:   Revision 1.224  2016/07/01 13:16:01  brouard
                    335:   Summary: Fixes
                    336: 
1.224     brouard   337:   Revision 1.223  2016/02/19 09:23:35  brouard
                    338:   Summary: temporary
                    339: 
1.223     brouard   340:   Revision 1.222  2016/02/17 08:14:50  brouard
                    341:   Summary: Probably last 0.98 stable version 0.98r6
                    342: 
1.222     brouard   343:   Revision 1.221  2016/02/15 23:35:36  brouard
                    344:   Summary: minor bug
                    345: 
1.220     brouard   346:   Revision 1.219  2016/02/15 00:48:12  brouard
                    347:   *** empty log message ***
                    348: 
1.219     brouard   349:   Revision 1.218  2016/02/12 11:29:23  brouard
                    350:   Summary: 0.99 Back projections
                    351: 
1.218     brouard   352:   Revision 1.217  2015/12/23 17:18:31  brouard
                    353:   Summary: Experimental backcast
                    354: 
1.217     brouard   355:   Revision 1.216  2015/12/18 17:32:11  brouard
                    356:   Summary: 0.98r4 Warning and status=-2
                    357: 
                    358:   Version 0.98r4 is now:
                    359:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    360:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    361:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    362: 
1.216     brouard   363:   Revision 1.215  2015/12/16 08:52:24  brouard
                    364:   Summary: 0.98r4 working
                    365: 
1.215     brouard   366:   Revision 1.214  2015/12/16 06:57:54  brouard
                    367:   Summary: temporary not working
                    368: 
1.214     brouard   369:   Revision 1.213  2015/12/11 18:22:17  brouard
                    370:   Summary: 0.98r4
                    371: 
1.213     brouard   372:   Revision 1.212  2015/11/21 12:47:24  brouard
                    373:   Summary: minor typo
                    374: 
1.212     brouard   375:   Revision 1.211  2015/11/21 12:41:11  brouard
                    376:   Summary: 0.98r3 with some graph of projected cross-sectional
                    377: 
                    378:   Author: Nicolas Brouard
                    379: 
1.211     brouard   380:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   381:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   382:   Summary: Adding ftolpl parameter
                    383:   Author: N Brouard
                    384: 
                    385:   We had difficulties to get smoothed confidence intervals. It was due
                    386:   to the period prevalence which wasn't computed accurately. The inner
                    387:   parameter ftolpl is now an outer parameter of the .imach parameter
                    388:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    389:   computation are long.
                    390: 
1.209     brouard   391:   Revision 1.208  2015/11/17 14:31:57  brouard
                    392:   Summary: temporary
                    393: 
1.208     brouard   394:   Revision 1.207  2015/10/27 17:36:57  brouard
                    395:   *** empty log message ***
                    396: 
1.207     brouard   397:   Revision 1.206  2015/10/24 07:14:11  brouard
                    398:   *** empty log message ***
                    399: 
1.206     brouard   400:   Revision 1.205  2015/10/23 15:50:53  brouard
                    401:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    402: 
1.205     brouard   403:   Revision 1.204  2015/10/01 16:20:26  brouard
                    404:   Summary: Some new graphs of contribution to likelihood
                    405: 
1.204     brouard   406:   Revision 1.203  2015/09/30 17:45:14  brouard
                    407:   Summary: looking at better estimation of the hessian
                    408: 
                    409:   Also a better criteria for convergence to the period prevalence And
                    410:   therefore adding the number of years needed to converge. (The
                    411:   prevalence in any alive state shold sum to one
                    412: 
1.203     brouard   413:   Revision 1.202  2015/09/22 19:45:16  brouard
                    414:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    415: 
1.202     brouard   416:   Revision 1.201  2015/09/15 17:34:58  brouard
                    417:   Summary: 0.98r0
                    418: 
                    419:   - Some new graphs like suvival functions
                    420:   - Some bugs fixed like model=1+age+V2.
                    421: 
1.201     brouard   422:   Revision 1.200  2015/09/09 16:53:55  brouard
                    423:   Summary: Big bug thanks to Flavia
                    424: 
                    425:   Even model=1+age+V2. did not work anymore
                    426: 
1.200     brouard   427:   Revision 1.199  2015/09/07 14:09:23  brouard
                    428:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    429: 
1.199     brouard   430:   Revision 1.198  2015/09/03 07:14:39  brouard
                    431:   Summary: 0.98q5 Flavia
                    432: 
1.198     brouard   433:   Revision 1.197  2015/09/01 18:24:39  brouard
                    434:   *** empty log message ***
                    435: 
1.197     brouard   436:   Revision 1.196  2015/08/18 23:17:52  brouard
                    437:   Summary: 0.98q5
                    438: 
1.196     brouard   439:   Revision 1.195  2015/08/18 16:28:39  brouard
                    440:   Summary: Adding a hack for testing purpose
                    441: 
                    442:   After reading the title, ftol and model lines, if the comment line has
                    443:   a q, starting with #q, the answer at the end of the run is quit. It
                    444:   permits to run test files in batch with ctest. The former workaround was
                    445:   $ echo q | imach foo.imach
                    446: 
1.195     brouard   447:   Revision 1.194  2015/08/18 13:32:00  brouard
                    448:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    449: 
1.194     brouard   450:   Revision 1.193  2015/08/04 07:17:42  brouard
                    451:   Summary: 0.98q4
                    452: 
1.193     brouard   453:   Revision 1.192  2015/07/16 16:49:02  brouard
                    454:   Summary: Fixing some outputs
                    455: 
1.192     brouard   456:   Revision 1.191  2015/07/14 10:00:33  brouard
                    457:   Summary: Some fixes
                    458: 
1.191     brouard   459:   Revision 1.190  2015/05/05 08:51:13  brouard
                    460:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    461: 
                    462:   Fix 1+age+.
                    463: 
1.190     brouard   464:   Revision 1.189  2015/04/30 14:45:16  brouard
                    465:   Summary: 0.98q2
                    466: 
1.189     brouard   467:   Revision 1.188  2015/04/30 08:27:53  brouard
                    468:   *** empty log message ***
                    469: 
1.188     brouard   470:   Revision 1.187  2015/04/29 09:11:15  brouard
                    471:   *** empty log message ***
                    472: 
1.187     brouard   473:   Revision 1.186  2015/04/23 12:01:52  brouard
                    474:   Summary: V1*age is working now, version 0.98q1
                    475: 
                    476:   Some codes had been disabled in order to simplify and Vn*age was
                    477:   working in the optimization phase, ie, giving correct MLE parameters,
                    478:   but, as usual, outputs were not correct and program core dumped.
                    479: 
1.186     brouard   480:   Revision 1.185  2015/03/11 13:26:42  brouard
                    481:   Summary: Inclusion of compile and links command line for Intel Compiler
                    482: 
1.185     brouard   483:   Revision 1.184  2015/03/11 11:52:39  brouard
                    484:   Summary: Back from Windows 8. Intel Compiler
                    485: 
1.184     brouard   486:   Revision 1.183  2015/03/10 20:34:32  brouard
                    487:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    488: 
                    489:   We use directest instead of original Powell test; probably no
                    490:   incidence on the results, but better justifications;
                    491:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    492:   wrong results.
                    493: 
1.183     brouard   494:   Revision 1.182  2015/02/12 08:19:57  brouard
                    495:   Summary: Trying to keep directest which seems simpler and more general
                    496:   Author: Nicolas Brouard
                    497: 
1.182     brouard   498:   Revision 1.181  2015/02/11 23:22:24  brouard
                    499:   Summary: Comments on Powell added
                    500: 
                    501:   Author:
                    502: 
1.181     brouard   503:   Revision 1.180  2015/02/11 17:33:45  brouard
                    504:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    505: 
1.180     brouard   506:   Revision 1.179  2015/01/04 09:57:06  brouard
                    507:   Summary: back to OS/X
                    508: 
1.179     brouard   509:   Revision 1.178  2015/01/04 09:35:48  brouard
                    510:   *** empty log message ***
                    511: 
1.178     brouard   512:   Revision 1.177  2015/01/03 18:40:56  brouard
                    513:   Summary: Still testing ilc32 on OSX
                    514: 
1.177     brouard   515:   Revision 1.176  2015/01/03 16:45:04  brouard
                    516:   *** empty log message ***
                    517: 
1.176     brouard   518:   Revision 1.175  2015/01/03 16:33:42  brouard
                    519:   *** empty log message ***
                    520: 
1.175     brouard   521:   Revision 1.174  2015/01/03 16:15:49  brouard
                    522:   Summary: Still in cross-compilation
                    523: 
1.174     brouard   524:   Revision 1.173  2015/01/03 12:06:26  brouard
                    525:   Summary: trying to detect cross-compilation
                    526: 
1.173     brouard   527:   Revision 1.172  2014/12/27 12:07:47  brouard
                    528:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    529: 
1.172     brouard   530:   Revision 1.171  2014/12/23 13:26:59  brouard
                    531:   Summary: Back from Visual C
                    532: 
                    533:   Still problem with utsname.h on Windows
                    534: 
1.171     brouard   535:   Revision 1.170  2014/12/23 11:17:12  brouard
                    536:   Summary: Cleaning some \%% back to %%
                    537: 
                    538:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    539: 
1.170     brouard   540:   Revision 1.169  2014/12/22 23:08:31  brouard
                    541:   Summary: 0.98p
                    542: 
                    543:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    544: 
1.169     brouard   545:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   546:   Summary: update
1.169     brouard   547: 
1.168     brouard   548:   Revision 1.167  2014/12/22 13:50:56  brouard
                    549:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    550: 
                    551:   Testing on Linux 64
                    552: 
1.167     brouard   553:   Revision 1.166  2014/12/22 11:40:47  brouard
                    554:   *** empty log message ***
                    555: 
1.166     brouard   556:   Revision 1.165  2014/12/16 11:20:36  brouard
                    557:   Summary: After compiling on Visual C
                    558: 
                    559:   * imach.c (Module): Merging 1.61 to 1.162
                    560: 
1.165     brouard   561:   Revision 1.164  2014/12/16 10:52:11  brouard
                    562:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    563: 
                    564:   * imach.c (Module): Merging 1.61 to 1.162
                    565: 
1.164     brouard   566:   Revision 1.163  2014/12/16 10:30:11  brouard
                    567:   * imach.c (Module): Merging 1.61 to 1.162
                    568: 
1.163     brouard   569:   Revision 1.162  2014/09/25 11:43:39  brouard
                    570:   Summary: temporary backup 0.99!
                    571: 
1.162     brouard   572:   Revision 1.1  2014/09/16 11:06:58  brouard
                    573:   Summary: With some code (wrong) for nlopt
                    574: 
                    575:   Author:
                    576: 
                    577:   Revision 1.161  2014/09/15 20:41:41  brouard
                    578:   Summary: Problem with macro SQR on Intel compiler
                    579: 
1.161     brouard   580:   Revision 1.160  2014/09/02 09:24:05  brouard
                    581:   *** empty log message ***
                    582: 
1.160     brouard   583:   Revision 1.159  2014/09/01 10:34:10  brouard
                    584:   Summary: WIN32
                    585:   Author: Brouard
                    586: 
1.159     brouard   587:   Revision 1.158  2014/08/27 17:11:51  brouard
                    588:   *** empty log message ***
                    589: 
1.158     brouard   590:   Revision 1.157  2014/08/27 16:26:55  brouard
                    591:   Summary: Preparing windows Visual studio version
                    592:   Author: Brouard
                    593: 
                    594:   In order to compile on Visual studio, time.h is now correct and time_t
                    595:   and tm struct should be used. difftime should be used but sometimes I
                    596:   just make the differences in raw time format (time(&now).
                    597:   Trying to suppress #ifdef LINUX
                    598:   Add xdg-open for __linux in order to open default browser.
                    599: 
1.157     brouard   600:   Revision 1.156  2014/08/25 20:10:10  brouard
                    601:   *** empty log message ***
                    602: 
1.156     brouard   603:   Revision 1.155  2014/08/25 18:32:34  brouard
                    604:   Summary: New compile, minor changes
                    605:   Author: Brouard
                    606: 
1.155     brouard   607:   Revision 1.154  2014/06/20 17:32:08  brouard
                    608:   Summary: Outputs now all graphs of convergence to period prevalence
                    609: 
1.154     brouard   610:   Revision 1.153  2014/06/20 16:45:46  brouard
                    611:   Summary: If 3 live state, convergence to period prevalence on same graph
                    612:   Author: Brouard
                    613: 
1.153     brouard   614:   Revision 1.152  2014/06/18 17:54:09  brouard
                    615:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    616: 
1.152     brouard   617:   Revision 1.151  2014/06/18 16:43:30  brouard
                    618:   *** empty log message ***
                    619: 
1.151     brouard   620:   Revision 1.150  2014/06/18 16:42:35  brouard
                    621:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    622:   Author: brouard
                    623: 
1.150     brouard   624:   Revision 1.149  2014/06/18 15:51:14  brouard
                    625:   Summary: Some fixes in parameter files errors
                    626:   Author: Nicolas Brouard
                    627: 
1.149     brouard   628:   Revision 1.148  2014/06/17 17:38:48  brouard
                    629:   Summary: Nothing new
                    630:   Author: Brouard
                    631: 
                    632:   Just a new packaging for OS/X version 0.98nS
                    633: 
1.148     brouard   634:   Revision 1.147  2014/06/16 10:33:11  brouard
                    635:   *** empty log message ***
                    636: 
1.147     brouard   637:   Revision 1.146  2014/06/16 10:20:28  brouard
                    638:   Summary: Merge
                    639:   Author: Brouard
                    640: 
                    641:   Merge, before building revised version.
                    642: 
1.146     brouard   643:   Revision 1.145  2014/06/10 21:23:15  brouard
                    644:   Summary: Debugging with valgrind
                    645:   Author: Nicolas Brouard
                    646: 
                    647:   Lot of changes in order to output the results with some covariates
                    648:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    649:   improve the code.
                    650:   No more memory valgrind error but a lot has to be done in order to
                    651:   continue the work of splitting the code into subroutines.
                    652:   Also, decodemodel has been improved. Tricode is still not
                    653:   optimal. nbcode should be improved. Documentation has been added in
                    654:   the source code.
                    655: 
1.144     brouard   656:   Revision 1.143  2014/01/26 09:45:38  brouard
                    657:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    658: 
                    659:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    660:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    661: 
1.143     brouard   662:   Revision 1.142  2014/01/26 03:57:36  brouard
                    663:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    664: 
                    665:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    666: 
1.142     brouard   667:   Revision 1.141  2014/01/26 02:42:01  brouard
                    668:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    669: 
1.141     brouard   670:   Revision 1.140  2011/09/02 10:37:54  brouard
                    671:   Summary: times.h is ok with mingw32 now.
                    672: 
1.140     brouard   673:   Revision 1.139  2010/06/14 07:50:17  brouard
                    674:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    675:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    676: 
1.139     brouard   677:   Revision 1.138  2010/04/30 18:19:40  brouard
                    678:   *** empty log message ***
                    679: 
1.138     brouard   680:   Revision 1.137  2010/04/29 18:11:38  brouard
                    681:   (Module): Checking covariates for more complex models
                    682:   than V1+V2. A lot of change to be done. Unstable.
                    683: 
1.137     brouard   684:   Revision 1.136  2010/04/26 20:30:53  brouard
                    685:   (Module): merging some libgsl code. Fixing computation
                    686:   of likelione (using inter/intrapolation if mle = 0) in order to
                    687:   get same likelihood as if mle=1.
                    688:   Some cleaning of code and comments added.
                    689: 
1.136     brouard   690:   Revision 1.135  2009/10/29 15:33:14  brouard
                    691:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    692: 
1.135     brouard   693:   Revision 1.134  2009/10/29 13:18:53  brouard
                    694:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    695: 
1.134     brouard   696:   Revision 1.133  2009/07/06 10:21:25  brouard
                    697:   just nforces
                    698: 
1.133     brouard   699:   Revision 1.132  2009/07/06 08:22:05  brouard
                    700:   Many tings
                    701: 
1.132     brouard   702:   Revision 1.131  2009/06/20 16:22:47  brouard
                    703:   Some dimensions resccaled
                    704: 
1.131     brouard   705:   Revision 1.130  2009/05/26 06:44:34  brouard
                    706:   (Module): Max Covariate is now set to 20 instead of 8. A
                    707:   lot of cleaning with variables initialized to 0. Trying to make
                    708:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    709: 
1.130     brouard   710:   Revision 1.129  2007/08/31 13:49:27  lievre
                    711:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    712: 
1.129     lievre    713:   Revision 1.128  2006/06/30 13:02:05  brouard
                    714:   (Module): Clarifications on computing e.j
                    715: 
1.128     brouard   716:   Revision 1.127  2006/04/28 18:11:50  brouard
                    717:   (Module): Yes the sum of survivors was wrong since
                    718:   imach-114 because nhstepm was no more computed in the age
                    719:   loop. Now we define nhstepma in the age loop.
                    720:   (Module): In order to speed up (in case of numerous covariates) we
                    721:   compute health expectancies (without variances) in a first step
                    722:   and then all the health expectancies with variances or standard
                    723:   deviation (needs data from the Hessian matrices) which slows the
                    724:   computation.
                    725:   In the future we should be able to stop the program is only health
                    726:   expectancies and graph are needed without standard deviations.
                    727: 
1.127     brouard   728:   Revision 1.126  2006/04/28 17:23:28  brouard
                    729:   (Module): Yes the sum of survivors was wrong since
                    730:   imach-114 because nhstepm was no more computed in the age
                    731:   loop. Now we define nhstepma in the age loop.
                    732:   Version 0.98h
                    733: 
1.126     brouard   734:   Revision 1.125  2006/04/04 15:20:31  lievre
                    735:   Errors in calculation of health expectancies. Age was not initialized.
                    736:   Forecasting file added.
                    737: 
                    738:   Revision 1.124  2006/03/22 17:13:53  lievre
                    739:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    740:   The log-likelihood is printed in the log file
                    741: 
                    742:   Revision 1.123  2006/03/20 10:52:43  brouard
                    743:   * imach.c (Module): <title> changed, corresponds to .htm file
                    744:   name. <head> headers where missing.
                    745: 
                    746:   * imach.c (Module): Weights can have a decimal point as for
                    747:   English (a comma might work with a correct LC_NUMERIC environment,
                    748:   otherwise the weight is truncated).
                    749:   Modification of warning when the covariates values are not 0 or
                    750:   1.
                    751:   Version 0.98g
                    752: 
                    753:   Revision 1.122  2006/03/20 09:45:41  brouard
                    754:   (Module): Weights can have a decimal point as for
                    755:   English (a comma might work with a correct LC_NUMERIC environment,
                    756:   otherwise the weight is truncated).
                    757:   Modification of warning when the covariates values are not 0 or
                    758:   1.
                    759:   Version 0.98g
                    760: 
                    761:   Revision 1.121  2006/03/16 17:45:01  lievre
                    762:   * imach.c (Module): Comments concerning covariates added
                    763: 
                    764:   * imach.c (Module): refinements in the computation of lli if
                    765:   status=-2 in order to have more reliable computation if stepm is
                    766:   not 1 month. Version 0.98f
                    767: 
                    768:   Revision 1.120  2006/03/16 15:10:38  lievre
                    769:   (Module): refinements in the computation of lli if
                    770:   status=-2 in order to have more reliable computation if stepm is
                    771:   not 1 month. Version 0.98f
                    772: 
                    773:   Revision 1.119  2006/03/15 17:42:26  brouard
                    774:   (Module): Bug if status = -2, the loglikelihood was
                    775:   computed as likelihood omitting the logarithm. Version O.98e
                    776: 
                    777:   Revision 1.118  2006/03/14 18:20:07  brouard
                    778:   (Module): varevsij Comments added explaining the second
                    779:   table of variances if popbased=1 .
                    780:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    781:   (Module): Function pstamp added
                    782:   (Module): Version 0.98d
                    783: 
                    784:   Revision 1.117  2006/03/14 17:16:22  brouard
                    785:   (Module): varevsij Comments added explaining the second
                    786:   table of variances if popbased=1 .
                    787:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    788:   (Module): Function pstamp added
                    789:   (Module): Version 0.98d
                    790: 
                    791:   Revision 1.116  2006/03/06 10:29:27  brouard
                    792:   (Module): Variance-covariance wrong links and
                    793:   varian-covariance of ej. is needed (Saito).
                    794: 
                    795:   Revision 1.115  2006/02/27 12:17:45  brouard
                    796:   (Module): One freematrix added in mlikeli! 0.98c
                    797: 
                    798:   Revision 1.114  2006/02/26 12:57:58  brouard
                    799:   (Module): Some improvements in processing parameter
                    800:   filename with strsep.
                    801: 
                    802:   Revision 1.113  2006/02/24 14:20:24  brouard
                    803:   (Module): Memory leaks checks with valgrind and:
                    804:   datafile was not closed, some imatrix were not freed and on matrix
                    805:   allocation too.
                    806: 
                    807:   Revision 1.112  2006/01/30 09:55:26  brouard
                    808:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    809: 
                    810:   Revision 1.111  2006/01/25 20:38:18  brouard
                    811:   (Module): Lots of cleaning and bugs added (Gompertz)
                    812:   (Module): Comments can be added in data file. Missing date values
                    813:   can be a simple dot '.'.
                    814: 
                    815:   Revision 1.110  2006/01/25 00:51:50  brouard
                    816:   (Module): Lots of cleaning and bugs added (Gompertz)
                    817: 
                    818:   Revision 1.109  2006/01/24 19:37:15  brouard
                    819:   (Module): Comments (lines starting with a #) are allowed in data.
                    820: 
                    821:   Revision 1.108  2006/01/19 18:05:42  lievre
                    822:   Gnuplot problem appeared...
                    823:   To be fixed
                    824: 
                    825:   Revision 1.107  2006/01/19 16:20:37  brouard
                    826:   Test existence of gnuplot in imach path
                    827: 
                    828:   Revision 1.106  2006/01/19 13:24:36  brouard
                    829:   Some cleaning and links added in html output
                    830: 
                    831:   Revision 1.105  2006/01/05 20:23:19  lievre
                    832:   *** empty log message ***
                    833: 
                    834:   Revision 1.104  2005/09/30 16:11:43  lievre
                    835:   (Module): sump fixed, loop imx fixed, and simplifications.
                    836:   (Module): If the status is missing at the last wave but we know
                    837:   that the person is alive, then we can code his/her status as -2
                    838:   (instead of missing=-1 in earlier versions) and his/her
                    839:   contributions to the likelihood is 1 - Prob of dying from last
                    840:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    841:   the healthy state at last known wave). Version is 0.98
                    842: 
                    843:   Revision 1.103  2005/09/30 15:54:49  lievre
                    844:   (Module): sump fixed, loop imx fixed, and simplifications.
                    845: 
                    846:   Revision 1.102  2004/09/15 17:31:30  brouard
                    847:   Add the possibility to read data file including tab characters.
                    848: 
                    849:   Revision 1.101  2004/09/15 10:38:38  brouard
                    850:   Fix on curr_time
                    851: 
                    852:   Revision 1.100  2004/07/12 18:29:06  brouard
                    853:   Add version for Mac OS X. Just define UNIX in Makefile
                    854: 
                    855:   Revision 1.99  2004/06/05 08:57:40  brouard
                    856:   *** empty log message ***
                    857: 
                    858:   Revision 1.98  2004/05/16 15:05:56  brouard
                    859:   New version 0.97 . First attempt to estimate force of mortality
                    860:   directly from the data i.e. without the need of knowing the health
                    861:   state at each age, but using a Gompertz model: log u =a + b*age .
                    862:   This is the basic analysis of mortality and should be done before any
                    863:   other analysis, in order to test if the mortality estimated from the
                    864:   cross-longitudinal survey is different from the mortality estimated
                    865:   from other sources like vital statistic data.
                    866: 
                    867:   The same imach parameter file can be used but the option for mle should be -3.
                    868: 
1.133     brouard   869:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   870:   former routines in order to include the new code within the former code.
                    871: 
                    872:   The output is very simple: only an estimate of the intercept and of
                    873:   the slope with 95% confident intervals.
                    874: 
                    875:   Current limitations:
                    876:   A) Even if you enter covariates, i.e. with the
                    877:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    878:   B) There is no computation of Life Expectancy nor Life Table.
                    879: 
                    880:   Revision 1.97  2004/02/20 13:25:42  lievre
                    881:   Version 0.96d. Population forecasting command line is (temporarily)
                    882:   suppressed.
                    883: 
                    884:   Revision 1.96  2003/07/15 15:38:55  brouard
                    885:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    886:   rewritten within the same printf. Workaround: many printfs.
                    887: 
                    888:   Revision 1.95  2003/07/08 07:54:34  brouard
                    889:   * imach.c (Repository):
                    890:   (Repository): Using imachwizard code to output a more meaningful covariance
                    891:   matrix (cov(a12,c31) instead of numbers.
                    892: 
                    893:   Revision 1.94  2003/06/27 13:00:02  brouard
                    894:   Just cleaning
                    895: 
                    896:   Revision 1.93  2003/06/25 16:33:55  brouard
                    897:   (Module): On windows (cygwin) function asctime_r doesn't
                    898:   exist so I changed back to asctime which exists.
                    899:   (Module): Version 0.96b
                    900: 
                    901:   Revision 1.92  2003/06/25 16:30:45  brouard
                    902:   (Module): On windows (cygwin) function asctime_r doesn't
                    903:   exist so I changed back to asctime which exists.
                    904: 
                    905:   Revision 1.91  2003/06/25 15:30:29  brouard
                    906:   * imach.c (Repository): Duplicated warning errors corrected.
                    907:   (Repository): Elapsed time after each iteration is now output. It
                    908:   helps to forecast when convergence will be reached. Elapsed time
                    909:   is stamped in powell.  We created a new html file for the graphs
                    910:   concerning matrix of covariance. It has extension -cov.htm.
                    911: 
                    912:   Revision 1.90  2003/06/24 12:34:15  brouard
                    913:   (Module): Some bugs corrected for windows. Also, when
                    914:   mle=-1 a template is output in file "or"mypar.txt with the design
                    915:   of the covariance matrix to be input.
                    916: 
                    917:   Revision 1.89  2003/06/24 12:30:52  brouard
                    918:   (Module): Some bugs corrected for windows. Also, when
                    919:   mle=-1 a template is output in file "or"mypar.txt with the design
                    920:   of the covariance matrix to be input.
                    921: 
                    922:   Revision 1.88  2003/06/23 17:54:56  brouard
                    923:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    924: 
                    925:   Revision 1.87  2003/06/18 12:26:01  brouard
                    926:   Version 0.96
                    927: 
                    928:   Revision 1.86  2003/06/17 20:04:08  brouard
                    929:   (Module): Change position of html and gnuplot routines and added
                    930:   routine fileappend.
                    931: 
                    932:   Revision 1.85  2003/06/17 13:12:43  brouard
                    933:   * imach.c (Repository): Check when date of death was earlier that
                    934:   current date of interview. It may happen when the death was just
                    935:   prior to the death. In this case, dh was negative and likelihood
                    936:   was wrong (infinity). We still send an "Error" but patch by
                    937:   assuming that the date of death was just one stepm after the
                    938:   interview.
                    939:   (Repository): Because some people have very long ID (first column)
                    940:   we changed int to long in num[] and we added a new lvector for
                    941:   memory allocation. But we also truncated to 8 characters (left
                    942:   truncation)
                    943:   (Repository): No more line truncation errors.
                    944: 
                    945:   Revision 1.84  2003/06/13 21:44:43  brouard
                    946:   * imach.c (Repository): Replace "freqsummary" at a correct
                    947:   place. It differs from routine "prevalence" which may be called
                    948:   many times. Probs is memory consuming and must be used with
                    949:   parcimony.
                    950:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    951: 
                    952:   Revision 1.83  2003/06/10 13:39:11  lievre
                    953:   *** empty log message ***
                    954: 
                    955:   Revision 1.82  2003/06/05 15:57:20  brouard
                    956:   Add log in  imach.c and  fullversion number is now printed.
                    957: 
                    958: */
                    959: /*
                    960:    Interpolated Markov Chain
                    961: 
                    962:   Short summary of the programme:
                    963:   
1.227     brouard   964:   This program computes Healthy Life Expectancies or State-specific
                    965:   (if states aren't health statuses) Expectancies from
                    966:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    967: 
                    968:   -1- a first survey ("cross") where individuals from different ages
                    969:   are interviewed on their health status or degree of disability (in
                    970:   the case of a health survey which is our main interest)
                    971: 
                    972:   -2- at least a second wave of interviews ("longitudinal") which
                    973:   measure each change (if any) in individual health status.  Health
                    974:   expectancies are computed from the time spent in each health state
                    975:   according to a model. More health states you consider, more time is
                    976:   necessary to reach the Maximum Likelihood of the parameters involved
                    977:   in the model.  The simplest model is the multinomial logistic model
                    978:   where pij is the probability to be observed in state j at the second
                    979:   wave conditional to be observed in state i at the first
                    980:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    981:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    982:   have a more complex model than "constant and age", you should modify
                    983:   the program where the markup *Covariates have to be included here
                    984:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   985:   convergence.
                    986: 
                    987:   The advantage of this computer programme, compared to a simple
                    988:   multinomial logistic model, is clear when the delay between waves is not
                    989:   identical for each individual. Also, if a individual missed an
                    990:   intermediate interview, the information is lost, but taken into
                    991:   account using an interpolation or extrapolation.  
                    992: 
                    993:   hPijx is the probability to be observed in state i at age x+h
                    994:   conditional to the observed state i at age x. The delay 'h' can be
                    995:   split into an exact number (nh*stepm) of unobserved intermediate
                    996:   states. This elementary transition (by month, quarter,
                    997:   semester or year) is modelled as a multinomial logistic.  The hPx
                    998:   matrix is simply the matrix product of nh*stepm elementary matrices
                    999:   and the contribution of each individual to the likelihood is simply
                   1000:   hPijx.
                   1001: 
                   1002:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard  1003:   of the life expectancies. It also computes the period (stable) prevalence.
                   1004: 
                   1005: Back prevalence and projections:
1.227     brouard  1006: 
                   1007:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                   1008:    double agemaxpar, double ftolpl, int *ncvyearp, double
                   1009:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                   1010:    mobilavproj)
                   1011: 
                   1012:     Computes the back prevalence limit for any combination of
                   1013:     covariate values k at any age between ageminpar and agemaxpar and
                   1014:     returns it in **bprlim. In the loops,
                   1015: 
                   1016:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                   1017:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                   1018: 
                   1019:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard  1020:    Computes for any combination of covariates k and any age between bage and fage 
                   1021:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   1022:                        oldm=oldms;savm=savms;
1.227     brouard  1023: 
1.267     brouard  1024:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard  1025:      Computes the transition matrix starting at age 'age' over
                   1026:      'nhstepm*hstepm*stepm' months (i.e. until
                   1027:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard  1028:      nhstepm*hstepm matrices. 
                   1029: 
                   1030:      Returns p3mat[i][j][h] after calling
                   1031:      p3mat[i][j][h]=matprod2(newm,
                   1032:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                   1033:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                   1034:      oldm);
1.226     brouard  1035: 
                   1036: Important routines
                   1037: 
                   1038: - func (or funcone), computes logit (pij) distinguishing
                   1039:   o fixed variables (single or product dummies or quantitative);
                   1040:   o varying variables by:
                   1041:    (1) wave (single, product dummies, quantitative), 
                   1042:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                   1043:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                   1044:        % varying dummy (not done) or quantitative (not done);
                   1045: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                   1046:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                   1047: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                   1048:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                   1049:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard  1050: 
1.226     brouard  1051: 
                   1052:   
1.133     brouard  1053:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                   1054:            Institut national d'études démographiques, Paris.
1.126     brouard  1055:   This software have been partly granted by Euro-REVES, a concerted action
                   1056:   from the European Union.
                   1057:   It is copyrighted identically to a GNU software product, ie programme and
                   1058:   software can be distributed freely for non commercial use. Latest version
                   1059:   can be accessed at http://euroreves.ined.fr/imach .
                   1060: 
                   1061:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                   1062:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                   1063:   
                   1064:   **********************************************************************/
                   1065: /*
                   1066:   main
                   1067:   read parameterfile
                   1068:   read datafile
                   1069:   concatwav
                   1070:   freqsummary
                   1071:   if (mle >= 1)
                   1072:     mlikeli
                   1073:   print results files
                   1074:   if mle==1 
                   1075:      computes hessian
                   1076:   read end of parameter file: agemin, agemax, bage, fage, estepm
                   1077:       begin-prev-date,...
                   1078:   open gnuplot file
                   1079:   open html file
1.145     brouard  1080:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                   1081:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                   1082:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                   1083:     freexexit2 possible for memory heap.
                   1084: 
                   1085:   h Pij x                         | pij_nom  ficrestpij
                   1086:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                   1087:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                   1088:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                   1089: 
                   1090:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                   1091:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                   1092:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                   1093:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                   1094:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                   1095: 
1.126     brouard  1096:   forecasting if prevfcast==1 prevforecast call prevalence()
                   1097:   health expectancies
                   1098:   Variance-covariance of DFLE
                   1099:   prevalence()
                   1100:    movingaverage()
                   1101:   varevsij() 
                   1102:   if popbased==1 varevsij(,popbased)
                   1103:   total life expectancies
                   1104:   Variance of period (stable) prevalence
                   1105:  end
                   1106: */
                   1107: 
1.187     brouard  1108: /* #define DEBUG */
                   1109: /* #define DEBUGBRENT */
1.203     brouard  1110: /* #define DEBUGLINMIN */
                   1111: /* #define DEBUGHESS */
                   1112: #define DEBUGHESSIJ
1.224     brouard  1113: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard  1114: #define POWELL /* Instead of NLOPT */
1.224     brouard  1115: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard  1116: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                   1117: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.319     brouard  1118: /* #define FLATSUP  *//* Suppresses directions where likelihood is flat */
1.126     brouard  1119: 
                   1120: #include <math.h>
                   1121: #include <stdio.h>
                   1122: #include <stdlib.h>
                   1123: #include <string.h>
1.226     brouard  1124: #include <ctype.h>
1.159     brouard  1125: 
                   1126: #ifdef _WIN32
                   1127: #include <io.h>
1.172     brouard  1128: #include <windows.h>
                   1129: #include <tchar.h>
1.159     brouard  1130: #else
1.126     brouard  1131: #include <unistd.h>
1.159     brouard  1132: #endif
1.126     brouard  1133: 
                   1134: #include <limits.h>
                   1135: #include <sys/types.h>
1.171     brouard  1136: 
                   1137: #if defined(__GNUC__)
                   1138: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1139: #endif
                   1140: 
1.126     brouard  1141: #include <sys/stat.h>
                   1142: #include <errno.h>
1.159     brouard  1143: /* extern int errno; */
1.126     brouard  1144: 
1.157     brouard  1145: /* #ifdef LINUX */
                   1146: /* #include <time.h> */
                   1147: /* #include "timeval.h" */
                   1148: /* #else */
                   1149: /* #include <sys/time.h> */
                   1150: /* #endif */
                   1151: 
1.126     brouard  1152: #include <time.h>
                   1153: 
1.136     brouard  1154: #ifdef GSL
                   1155: #include <gsl/gsl_errno.h>
                   1156: #include <gsl/gsl_multimin.h>
                   1157: #endif
                   1158: 
1.167     brouard  1159: 
1.162     brouard  1160: #ifdef NLOPT
                   1161: #include <nlopt.h>
                   1162: typedef struct {
                   1163:   double (* function)(double [] );
                   1164: } myfunc_data ;
                   1165: #endif
                   1166: 
1.126     brouard  1167: /* #include <libintl.h> */
                   1168: /* #define _(String) gettext (String) */
                   1169: 
1.251     brouard  1170: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1171: 
                   1172: #define GNUPLOTPROGRAM "gnuplot"
                   1173: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1174: #define FILENAMELENGTH 132
                   1175: 
                   1176: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1177: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1178: 
1.144     brouard  1179: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1180: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1181: 
                   1182: #define NINTERVMAX 8
1.144     brouard  1183: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1184: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.318     brouard  1185: #define NCOVMAX 30  /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1186: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1187: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1188: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1189: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1190: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1191: /* #define AGESUP 130 */
1.288     brouard  1192: /* #define AGESUP 150 */
                   1193: #define AGESUP 200
1.268     brouard  1194: #define AGEINF 0
1.218     brouard  1195: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1196: #define AGEBASE 40
1.194     brouard  1197: #define AGEOVERFLOW 1.e20
1.164     brouard  1198: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1199: #ifdef _WIN32
                   1200: #define DIRSEPARATOR '\\'
                   1201: #define CHARSEPARATOR "\\"
                   1202: #define ODIRSEPARATOR '/'
                   1203: #else
1.126     brouard  1204: #define DIRSEPARATOR '/'
                   1205: #define CHARSEPARATOR "/"
                   1206: #define ODIRSEPARATOR '\\'
                   1207: #endif
                   1208: 
1.323   ! brouard  1209: /* $Id: imach.c,v 1.322 2022/07/22 12:27:48 brouard Exp $ */
1.126     brouard  1210: /* $State: Exp $ */
1.196     brouard  1211: #include "version.h"
                   1212: char version[]=__IMACH_VERSION__;
1.323   ! brouard  1213: char copyright[]="July 2022,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2020, Nihon University 2021-202, INED 2000-2022";
        !          1214: char fullversion[]="$Revision: 1.322 $ $Date: 2022/07/22 12:27:48 $"; 
1.126     brouard  1215: char strstart[80];
                   1216: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1217: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1218: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1219: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1220: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1221: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1222: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1223: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1224: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1225: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1226: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1227: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1228: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1229: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1230: int nsd=0; /**< Total number of single dummy variables (output) */
                   1231: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1232: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1233: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1234: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1235: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1236: int cptcov=0; /* Working variable */
1.290     brouard  1237: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1238: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.302     brouard  1239: int npar=NPARMAX; /* Number of parameters (nlstate+ndeath-1)*nlstate*ncovmodel; */
1.126     brouard  1240: int nlstate=2; /* Number of live states */
                   1241: int ndeath=1; /* Number of dead states */
1.130     brouard  1242: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1243: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1244: int popbased=0;
                   1245: 
                   1246: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1247: int maxwav=0; /* Maxim number of waves */
                   1248: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1249: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1250: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1251:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1252: int mle=1, weightopt=0;
1.126     brouard  1253: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1254: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1255: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1256:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1257: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1258: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1259: 
1.130     brouard  1260: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1261: double **matprod2(); /* test */
1.126     brouard  1262: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1263: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1264: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1265: 
1.136     brouard  1266: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1267: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1268: FILE *ficlog, *ficrespow;
1.130     brouard  1269: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1270: double fretone; /* Only one call to likelihood */
1.130     brouard  1271: long ipmx=0; /* Number of contributions */
1.126     brouard  1272: double sw; /* Sum of weights */
                   1273: char filerespow[FILENAMELENGTH];
                   1274: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1275: FILE *ficresilk;
                   1276: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1277: FILE *ficresprobmorprev;
                   1278: FILE *fichtm, *fichtmcov; /* Html File */
                   1279: FILE *ficreseij;
                   1280: char filerese[FILENAMELENGTH];
                   1281: FILE *ficresstdeij;
                   1282: char fileresstde[FILENAMELENGTH];
                   1283: FILE *ficrescveij;
                   1284: char filerescve[FILENAMELENGTH];
                   1285: FILE  *ficresvij;
                   1286: char fileresv[FILENAMELENGTH];
1.269     brouard  1287: 
1.126     brouard  1288: char title[MAXLINE];
1.234     brouard  1289: char model[MAXLINE]; /**< The model line */
1.217     brouard  1290: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1291: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1292: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1293: char command[FILENAMELENGTH];
                   1294: int  outcmd=0;
                   1295: 
1.217     brouard  1296: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1297: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1298: char filelog[FILENAMELENGTH]; /* Log file */
                   1299: char filerest[FILENAMELENGTH];
                   1300: char fileregp[FILENAMELENGTH];
                   1301: char popfile[FILENAMELENGTH];
                   1302: 
                   1303: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1304: 
1.157     brouard  1305: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1306: /* struct timezone tzp; */
                   1307: /* extern int gettimeofday(); */
                   1308: struct tm tml, *gmtime(), *localtime();
                   1309: 
                   1310: extern time_t time();
                   1311: 
                   1312: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1313: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1314: struct tm tm;
                   1315: 
1.126     brouard  1316: char strcurr[80], strfor[80];
                   1317: 
                   1318: char *endptr;
                   1319: long lval;
                   1320: double dval;
                   1321: 
                   1322: #define NR_END 1
                   1323: #define FREE_ARG char*
                   1324: #define FTOL 1.0e-10
                   1325: 
                   1326: #define NRANSI 
1.240     brouard  1327: #define ITMAX 200
                   1328: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1329: 
                   1330: #define TOL 2.0e-4 
                   1331: 
                   1332: #define CGOLD 0.3819660 
                   1333: #define ZEPS 1.0e-10 
                   1334: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1335: 
                   1336: #define GOLD 1.618034 
                   1337: #define GLIMIT 100.0 
                   1338: #define TINY 1.0e-20 
                   1339: 
                   1340: static double maxarg1,maxarg2;
                   1341: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1342: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1343:   
                   1344: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1345: #define rint(a) floor(a+0.5)
1.166     brouard  1346: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1347: #define mytinydouble 1.0e-16
1.166     brouard  1348: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1349: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1350: /* static double dsqrarg; */
                   1351: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1352: static double sqrarg;
                   1353: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1354: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1355: int agegomp= AGEGOMP;
                   1356: 
                   1357: int imx; 
                   1358: int stepm=1;
                   1359: /* Stepm, step in month: minimum step interpolation*/
                   1360: 
                   1361: int estepm;
                   1362: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1363: 
                   1364: int m,nb;
                   1365: long *num;
1.197     brouard  1366: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1367: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1368:                   covariate for which somebody answered excluding 
                   1369:                   undefined. Usually 2: 0 and 1. */
                   1370: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1371:                             covariate for which somebody answered including 
                   1372:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1373: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1374: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1375: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1376: double *ageexmed,*agecens;
                   1377: double dateintmean=0;
1.296     brouard  1378:   double anprojd, mprojd, jprojd; /* For eventual projections */
                   1379:   double anprojf, mprojf, jprojf;
1.126     brouard  1380: 
1.296     brouard  1381:   double anbackd, mbackd, jbackd; /* For eventual backprojections */
                   1382:   double anbackf, mbackf, jbackf;
                   1383:   double jintmean,mintmean,aintmean;  
1.126     brouard  1384: double *weight;
                   1385: int **s; /* Status */
1.141     brouard  1386: double *agedc;
1.145     brouard  1387: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1388:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1389:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1390: double **coqvar; /* Fixed quantitative covariate nqv */
                   1391: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1392: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1393: double  idx; 
                   1394: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.319     brouard  1395: /* Some documentation */
                   1396:       /*   Design original data
                   1397:        *  V1   V2   V3   V4  V5  V6  V7  V8  Weight ddb ddth d1st s1 V9 V10 V11 V12 s2 V9 V10 V11 V12 
                   1398:        *  <          ncovcol=6   >   nqv=2 (V7 V8)                   dv dv  dv  qtv    dv dv  dvv qtv
                   1399:        *                                                             ntv=3     nqtv=1
                   1400:        *  cptcovn number of covariates (not including constant and age) = # of + plus 1 = 10+1=11
                   1401:        * For time varying covariate, quanti or dummies
                   1402:        *       cotqvar[wav][iv(1 to nqtv)][i]= [1][12][i]=(V12) quanti
                   1403:        *       cotvar[wav][ntv+iv][i]= [3+(1 to nqtv)][i]=(V12) quanti
                   1404:        *       cotvar[wav][iv(1 to ntv)][i]= [1][1][i]=(V9) dummies at wav 1
                   1405:        *       cotvar[wav][iv(1 to ntv)][i]= [1][2][i]=(V10) dummies at wav 1
                   1406:        *       covar[k,i], value of kth fixed covariate dummy or quanti :
                   1407:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   1408:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8 + V9 + V9*age + V10
                   1409:        *   k=  1    2      3       4     5       6      7        8   9     10       11 
                   1410:        */
                   1411: /* According to the model, more columns can be added to covar by the product of covariates */
1.318     brouard  1412: /* ncovcol=1(Males=0 Females=1) nqv=1(raedyrs) ntv=2(withoutiadl=0 withiadl=1, witoutadl=0 withoutadl=1) nqtv=1(bmi) nlstate=3 ndeath=1
                   1413:   # States 1=Coresidence, 2 Living alone, 3 Institution
                   1414:   # V1=sex, V2=raedyrs Quant Fixed, State=livarnb4..livarnb11, V3=iadl4..iald11, V4=adlw4..adlw11, V5=r4bmi..r11bmi
                   1415: */
1.319     brouard  1416: /*             V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1417: /*    k        1  2   3   4     5    6    7     8    9 */
                   1418: /*Typevar[k]=  0  0   0   2     1    0    2     1    0 *//*0 for simple covariate (dummy, quantitative,*/
                   1419:                                                          /* fixed or varying), 1 for age product, 2 for*/
                   1420:                                                          /* product */
                   1421: /*Dummy[k]=    1  0   0   1     3    1    1     2    0 *//*Dummy[k] 0=dummy (0 1), 1 quantitative */
                   1422:                                                          /*(single or product without age), 2 dummy*/
                   1423:                                                          /* with age product, 3 quant with age product*/
                   1424: /*Tvar[k]=     5  4   3   6     5    2    7     1    1 */
                   1425: /*    nsd         1   2                              3 */ /* Counting single dummies covar fixed or tv */
                   1426: /*TvarsD[nsd]     4   3                              1 */ /* ID of single dummy cova fixed or timevary*/
                   1427: /*TvarsDind[k]    2   3                              9 */ /* position K of single dummy cova */
                   1428: /*    nsq      1                     2                 */ /* Counting single quantit tv */
                   1429: /* TvarsQ[k]   5                     2                 */ /* Number of single quantitative cova */
                   1430: /* TvarsQind   1                     6                 */ /* position K of single quantitative cova */
                   1431: /* Tprod[i]=k             1               2            */ /* Position in model of the ith prod without age */
                   1432: /* cptcovage                    1               2      */ /* Counting cov*age in the model equation */
                   1433: /* Tage[cptcovage]=k            5               8      */ /* Position in the model of ith cov*age */
                   1434: /* Tvard[1][1]@4={4,3,1,2}    V4*V3 V1*V2              */ /* Position in model of the ith prod without age */
                   1435: /* TvarF TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  ID of fixed covariates or product V2, V1*V2, V1 */
1.320     brouard  1436: /* TvarFind;  TvarFind[1]=6,  TvarFind[2]=7, TvarFind[3]=9 *//* Inverse V2(6) is first fixed (single or prod)  */
1.234     brouard  1437: /* Type                    */
                   1438: /* V         1  2  3  4  5 */
                   1439: /*           F  F  V  V  V */
                   1440: /*           D  Q  D  D  Q */
                   1441: /*                         */
                   1442: int *TvarsD;
                   1443: int *TvarsDind;
                   1444: int *TvarsQ;
                   1445: int *TvarsQind;
                   1446: 
1.318     brouard  1447: #define MAXRESULTLINESPONE 10+1
1.235     brouard  1448: int nresult=0;
1.258     brouard  1449: int parameterline=0; /* # of the parameter (type) line */
1.318     brouard  1450: int TKresult[MAXRESULTLINESPONE];
                   1451: int Tresult[MAXRESULTLINESPONE][NCOVMAX];/* For dummy variable , value (output) */
                   1452: int Tinvresult[MAXRESULTLINESPONE][NCOVMAX];/* For dummy variable , value (output) */
                   1453: int Tvresult[MAXRESULTLINESPONE][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1454: double Tqresult[MAXRESULTLINESPONE][NCOVMAX]; /* For quantitative variable , value (output) */
                   1455: double Tqinvresult[MAXRESULTLINESPONE][NCOVMAX]; /* For quantitative variable , value (output) */
                   1456: int Tvqresult[MAXRESULTLINESPONE][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1457: 
                   1458: /* ncovcol=1(Males=0 Females=1) nqv=1(raedyrs) ntv=2(withoutiadl=0 withiadl=1, witoutadl=0 withoutadl=1) nqtv=1(bmi) nlstate=3 ndeath=1
                   1459:   # States 1=Coresidence, 2 Living alone, 3 Institution
                   1460:   # V1=sex, V2=raedyrs Quant Fixed, State=livarnb4..livarnb11, V3=iadl4..iald11, V4=adlw4..adlw11, V5=r4bmi..r11bmi
                   1461: */
1.234     brouard  1462: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1463: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1464: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1465: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1466: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1467: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1468: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1469: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1470: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1471: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1472: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1473: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1474: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1475: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1476: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1477: 
1.230     brouard  1478: int *Tvarsel; /**< Selected covariates for output */
                   1479: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1480: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1481: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1482: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1483: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1484: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1485: int *Tage;
1.227     brouard  1486: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1487: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1488: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1489: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1490: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1491: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1492: int **Tvard;
                   1493: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1494: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1495: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1496:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1497:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1498: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1499: double *lsurv, *lpop, *tpop;
                   1500: 
1.231     brouard  1501: #define FD 1; /* Fixed dummy covariate */
                   1502: #define FQ 2; /* Fixed quantitative covariate */
                   1503: #define FP 3; /* Fixed product covariate */
                   1504: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1505: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1506: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1507: #define VD 10; /* Varying dummy covariate */
                   1508: #define VQ 11; /* Varying quantitative covariate */
                   1509: #define VP 12; /* Varying product covariate */
                   1510: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1511: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1512: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1513: #define APFD 16; /* Age product * fixed dummy covariate */
                   1514: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1515: #define APVD 18; /* Age product * varying dummy covariate */
                   1516: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1517: 
                   1518: #define FTYPE 1; /* Fixed covariate */
                   1519: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1520: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1521: 
                   1522: struct kmodel{
                   1523:        int maintype; /* main type */
                   1524:        int subtype; /* subtype */
                   1525: };
                   1526: struct kmodel modell[NCOVMAX];
                   1527: 
1.143     brouard  1528: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1529: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1530: 
                   1531: /**************** split *************************/
                   1532: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1533: {
                   1534:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1535:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1536:   */ 
                   1537:   char *ss;                            /* pointer */
1.186     brouard  1538:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1539: 
                   1540:   l1 = strlen(path );                  /* length of path */
                   1541:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1542:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1543:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1544:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1545:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1546:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1547:     /* get current working directory */
                   1548:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1549: #ifdef WIN32
                   1550:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1551: #else
                   1552:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1553: #endif
1.126     brouard  1554:       return( GLOCK_ERROR_GETCWD );
                   1555:     }
                   1556:     /* got dirc from getcwd*/
                   1557:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1558:   } else {                             /* strip directory from path */
1.126     brouard  1559:     ss++;                              /* after this, the filename */
                   1560:     l2 = strlen( ss );                 /* length of filename */
                   1561:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1562:     strcpy( name, ss );                /* save file name */
                   1563:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1564:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1565:     printf(" DIRC2 = %s \n",dirc);
                   1566:   }
                   1567:   /* We add a separator at the end of dirc if not exists */
                   1568:   l1 = strlen( dirc );                 /* length of directory */
                   1569:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1570:     dirc[l1] =  DIRSEPARATOR;
                   1571:     dirc[l1+1] = 0; 
                   1572:     printf(" DIRC3 = %s \n",dirc);
                   1573:   }
                   1574:   ss = strrchr( name, '.' );           /* find last / */
                   1575:   if (ss >0){
                   1576:     ss++;
                   1577:     strcpy(ext,ss);                    /* save extension */
                   1578:     l1= strlen( name);
                   1579:     l2= strlen(ss)+1;
                   1580:     strncpy( finame, name, l1-l2);
                   1581:     finame[l1-l2]= 0;
                   1582:   }
                   1583: 
                   1584:   return( 0 );                         /* we're done */
                   1585: }
                   1586: 
                   1587: 
                   1588: /******************************************/
                   1589: 
                   1590: void replace_back_to_slash(char *s, char*t)
                   1591: {
                   1592:   int i;
                   1593:   int lg=0;
                   1594:   i=0;
                   1595:   lg=strlen(t);
                   1596:   for(i=0; i<= lg; i++) {
                   1597:     (s[i] = t[i]);
                   1598:     if (t[i]== '\\') s[i]='/';
                   1599:   }
                   1600: }
                   1601: 
1.132     brouard  1602: char *trimbb(char *out, char *in)
1.137     brouard  1603: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1604:   char *s;
                   1605:   s=out;
                   1606:   while (*in != '\0'){
1.137     brouard  1607:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1608:       in++;
                   1609:     }
                   1610:     *out++ = *in++;
                   1611:   }
                   1612:   *out='\0';
                   1613:   return s;
                   1614: }
                   1615: 
1.187     brouard  1616: /* char *substrchaine(char *out, char *in, char *chain) */
                   1617: /* { */
                   1618: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1619: /*   char *s, *t; */
                   1620: /*   t=in;s=out; */
                   1621: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1622: /*     *out++ = *in++; */
                   1623: /*   } */
                   1624: 
                   1625: /*   /\* *in matches *chain *\/ */
                   1626: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1627: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1628: /*   } */
                   1629: /*   in--; chain--; */
                   1630: /*   while ( (*in != '\0')){ */
                   1631: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1632: /*     *out++ = *in++; */
                   1633: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1634: /*   } */
                   1635: /*   *out='\0'; */
                   1636: /*   out=s; */
                   1637: /*   return out; */
                   1638: /* } */
                   1639: char *substrchaine(char *out, char *in, char *chain)
                   1640: {
                   1641:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1642:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1643: 
                   1644:   char *strloc;
                   1645: 
                   1646:   strcpy (out, in); 
                   1647:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1648:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1649:   if(strloc != NULL){ 
                   1650:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1651:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1652:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1653:   }
                   1654:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1655:   return out;
                   1656: }
                   1657: 
                   1658: 
1.145     brouard  1659: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1660: {
1.187     brouard  1661:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1662:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.310     brouard  1663:      gives alocc="abcdef" and blocc="ghi2j".
1.145     brouard  1664:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1665:   */
1.160     brouard  1666:   char *s, *t;
1.145     brouard  1667:   t=in;s=in;
                   1668:   while ((*in != occ) && (*in != '\0')){
                   1669:     *alocc++ = *in++;
                   1670:   }
                   1671:   if( *in == occ){
                   1672:     *(alocc)='\0';
                   1673:     s=++in;
                   1674:   }
                   1675:  
                   1676:   if (s == t) {/* occ not found */
                   1677:     *(alocc-(in-s))='\0';
                   1678:     in=s;
                   1679:   }
                   1680:   while ( *in != '\0'){
                   1681:     *blocc++ = *in++;
                   1682:   }
                   1683: 
                   1684:   *blocc='\0';
                   1685:   return t;
                   1686: }
1.137     brouard  1687: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1688: {
1.187     brouard  1689:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1690:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1691:      gives blocc="abcdef2ghi" and alocc="j".
                   1692:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1693:   */
                   1694:   char *s, *t;
                   1695:   t=in;s=in;
                   1696:   while (*in != '\0'){
                   1697:     while( *in == occ){
                   1698:       *blocc++ = *in++;
                   1699:       s=in;
                   1700:     }
                   1701:     *blocc++ = *in++;
                   1702:   }
                   1703:   if (s == t) /* occ not found */
                   1704:     *(blocc-(in-s))='\0';
                   1705:   else
                   1706:     *(blocc-(in-s)-1)='\0';
                   1707:   in=s;
                   1708:   while ( *in != '\0'){
                   1709:     *alocc++ = *in++;
                   1710:   }
                   1711: 
                   1712:   *alocc='\0';
                   1713:   return s;
                   1714: }
                   1715: 
1.126     brouard  1716: int nbocc(char *s, char occ)
                   1717: {
                   1718:   int i,j=0;
                   1719:   int lg=20;
                   1720:   i=0;
                   1721:   lg=strlen(s);
                   1722:   for(i=0; i<= lg; i++) {
1.234     brouard  1723:     if  (s[i] == occ ) j++;
1.126     brouard  1724:   }
                   1725:   return j;
                   1726: }
                   1727: 
1.137     brouard  1728: /* void cutv(char *u,char *v, char*t, char occ) */
                   1729: /* { */
                   1730: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1731: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1732: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1733: /*   int i,lg,j,p=0; */
                   1734: /*   i=0; */
                   1735: /*   lg=strlen(t); */
                   1736: /*   for(j=0; j<=lg-1; j++) { */
                   1737: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1738: /*   } */
1.126     brouard  1739: 
1.137     brouard  1740: /*   for(j=0; j<p; j++) { */
                   1741: /*     (u[j] = t[j]); */
                   1742: /*   } */
                   1743: /*      u[p]='\0'; */
1.126     brouard  1744: 
1.137     brouard  1745: /*    for(j=0; j<= lg; j++) { */
                   1746: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1747: /*   } */
                   1748: /* } */
1.126     brouard  1749: 
1.160     brouard  1750: #ifdef _WIN32
                   1751: char * strsep(char **pp, const char *delim)
                   1752: {
                   1753:   char *p, *q;
                   1754:          
                   1755:   if ((p = *pp) == NULL)
                   1756:     return 0;
                   1757:   if ((q = strpbrk (p, delim)) != NULL)
                   1758:   {
                   1759:     *pp = q + 1;
                   1760:     *q = '\0';
                   1761:   }
                   1762:   else
                   1763:     *pp = 0;
                   1764:   return p;
                   1765: }
                   1766: #endif
                   1767: 
1.126     brouard  1768: /********************** nrerror ********************/
                   1769: 
                   1770: void nrerror(char error_text[])
                   1771: {
                   1772:   fprintf(stderr,"ERREUR ...\n");
                   1773:   fprintf(stderr,"%s\n",error_text);
                   1774:   exit(EXIT_FAILURE);
                   1775: }
                   1776: /*********************** vector *******************/
                   1777: double *vector(int nl, int nh)
                   1778: {
                   1779:   double *v;
                   1780:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1781:   if (!v) nrerror("allocation failure in vector");
                   1782:   return v-nl+NR_END;
                   1783: }
                   1784: 
                   1785: /************************ free vector ******************/
                   1786: void free_vector(double*v, int nl, int nh)
                   1787: {
                   1788:   free((FREE_ARG)(v+nl-NR_END));
                   1789: }
                   1790: 
                   1791: /************************ivector *******************************/
                   1792: int *ivector(long nl,long nh)
                   1793: {
                   1794:   int *v;
                   1795:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1796:   if (!v) nrerror("allocation failure in ivector");
                   1797:   return v-nl+NR_END;
                   1798: }
                   1799: 
                   1800: /******************free ivector **************************/
                   1801: void free_ivector(int *v, long nl, long nh)
                   1802: {
                   1803:   free((FREE_ARG)(v+nl-NR_END));
                   1804: }
                   1805: 
                   1806: /************************lvector *******************************/
                   1807: long *lvector(long nl,long nh)
                   1808: {
                   1809:   long *v;
                   1810:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1811:   if (!v) nrerror("allocation failure in ivector");
                   1812:   return v-nl+NR_END;
                   1813: }
                   1814: 
                   1815: /******************free lvector **************************/
                   1816: void free_lvector(long *v, long nl, long nh)
                   1817: {
                   1818:   free((FREE_ARG)(v+nl-NR_END));
                   1819: }
                   1820: 
                   1821: /******************* imatrix *******************************/
                   1822: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1823:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1824: { 
                   1825:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1826:   int **m; 
                   1827:   
                   1828:   /* allocate pointers to rows */ 
                   1829:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1830:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1831:   m += NR_END; 
                   1832:   m -= nrl; 
                   1833:   
                   1834:   
                   1835:   /* allocate rows and set pointers to them */ 
                   1836:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1837:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1838:   m[nrl] += NR_END; 
                   1839:   m[nrl] -= ncl; 
                   1840:   
                   1841:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1842:   
                   1843:   /* return pointer to array of pointers to rows */ 
                   1844:   return m; 
                   1845: } 
                   1846: 
                   1847: /****************** free_imatrix *************************/
                   1848: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1849:       int **m;
                   1850:       long nch,ncl,nrh,nrl; 
                   1851:      /* free an int matrix allocated by imatrix() */ 
                   1852: { 
                   1853:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1854:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1855: } 
                   1856: 
                   1857: /******************* matrix *******************************/
                   1858: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1859: {
                   1860:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1861:   double **m;
                   1862: 
                   1863:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1864:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1865:   m += NR_END;
                   1866:   m -= nrl;
                   1867: 
                   1868:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1869:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1870:   m[nrl] += NR_END;
                   1871:   m[nrl] -= ncl;
                   1872: 
                   1873:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1874:   return m;
1.145     brouard  1875:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1876: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1877: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1878:    */
                   1879: }
                   1880: 
                   1881: /*************************free matrix ************************/
                   1882: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1883: {
                   1884:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1885:   free((FREE_ARG)(m+nrl-NR_END));
                   1886: }
                   1887: 
                   1888: /******************* ma3x *******************************/
                   1889: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1890: {
                   1891:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1892:   double ***m;
                   1893: 
                   1894:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1895:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1896:   m += NR_END;
                   1897:   m -= nrl;
                   1898: 
                   1899:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1900:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1901:   m[nrl] += NR_END;
                   1902:   m[nrl] -= ncl;
                   1903: 
                   1904:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1905: 
                   1906:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1907:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1908:   m[nrl][ncl] += NR_END;
                   1909:   m[nrl][ncl] -= nll;
                   1910:   for (j=ncl+1; j<=nch; j++) 
                   1911:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1912:   
                   1913:   for (i=nrl+1; i<=nrh; i++) {
                   1914:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1915:     for (j=ncl+1; j<=nch; j++) 
                   1916:       m[i][j]=m[i][j-1]+nlay;
                   1917:   }
                   1918:   return m; 
                   1919:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1920:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1921:   */
                   1922: }
                   1923: 
                   1924: /*************************free ma3x ************************/
                   1925: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1926: {
                   1927:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1928:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1929:   free((FREE_ARG)(m+nrl-NR_END));
                   1930: }
                   1931: 
                   1932: /*************** function subdirf ***********/
                   1933: char *subdirf(char fileres[])
                   1934: {
                   1935:   /* Caution optionfilefiname is hidden */
                   1936:   strcpy(tmpout,optionfilefiname);
                   1937:   strcat(tmpout,"/"); /* Add to the right */
                   1938:   strcat(tmpout,fileres);
                   1939:   return tmpout;
                   1940: }
                   1941: 
                   1942: /*************** function subdirf2 ***********/
                   1943: char *subdirf2(char fileres[], char *preop)
                   1944: {
1.314     brouard  1945:   /* Example subdirf2(optionfilefiname,"FB_") with optionfilefiname="texte", result="texte/FB_texte"
                   1946:  Errors in subdirf, 2, 3 while printing tmpout is
1.315     brouard  1947:  rewritten within the same printf. Workaround: many printfs */
1.126     brouard  1948:   /* Caution optionfilefiname is hidden */
                   1949:   strcpy(tmpout,optionfilefiname);
                   1950:   strcat(tmpout,"/");
                   1951:   strcat(tmpout,preop);
                   1952:   strcat(tmpout,fileres);
                   1953:   return tmpout;
                   1954: }
                   1955: 
                   1956: /*************** function subdirf3 ***********/
                   1957: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1958: {
                   1959:   
                   1960:   /* Caution optionfilefiname is hidden */
                   1961:   strcpy(tmpout,optionfilefiname);
                   1962:   strcat(tmpout,"/");
                   1963:   strcat(tmpout,preop);
                   1964:   strcat(tmpout,preop2);
                   1965:   strcat(tmpout,fileres);
                   1966:   return tmpout;
                   1967: }
1.213     brouard  1968:  
                   1969: /*************** function subdirfext ***********/
                   1970: char *subdirfext(char fileres[], char *preop, char *postop)
                   1971: {
                   1972:   
                   1973:   strcpy(tmpout,preop);
                   1974:   strcat(tmpout,fileres);
                   1975:   strcat(tmpout,postop);
                   1976:   return tmpout;
                   1977: }
1.126     brouard  1978: 
1.213     brouard  1979: /*************** function subdirfext3 ***********/
                   1980: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1981: {
                   1982:   
                   1983:   /* Caution optionfilefiname is hidden */
                   1984:   strcpy(tmpout,optionfilefiname);
                   1985:   strcat(tmpout,"/");
                   1986:   strcat(tmpout,preop);
                   1987:   strcat(tmpout,fileres);
                   1988:   strcat(tmpout,postop);
                   1989:   return tmpout;
                   1990: }
                   1991:  
1.162     brouard  1992: char *asc_diff_time(long time_sec, char ascdiff[])
                   1993: {
                   1994:   long sec_left, days, hours, minutes;
                   1995:   days = (time_sec) / (60*60*24);
                   1996:   sec_left = (time_sec) % (60*60*24);
                   1997:   hours = (sec_left) / (60*60) ;
                   1998:   sec_left = (sec_left) %(60*60);
                   1999:   minutes = (sec_left) /60;
                   2000:   sec_left = (sec_left) % (60);
                   2001:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   2002:   return ascdiff;
                   2003: }
                   2004: 
1.126     brouard  2005: /***************** f1dim *************************/
                   2006: extern int ncom; 
                   2007: extern double *pcom,*xicom;
                   2008: extern double (*nrfunc)(double []); 
                   2009:  
                   2010: double f1dim(double x) 
                   2011: { 
                   2012:   int j; 
                   2013:   double f;
                   2014:   double *xt; 
                   2015:  
                   2016:   xt=vector(1,ncom); 
                   2017:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   2018:   f=(*nrfunc)(xt); 
                   2019:   free_vector(xt,1,ncom); 
                   2020:   return f; 
                   2021: } 
                   2022: 
                   2023: /*****************brent *************************/
                   2024: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  2025: {
                   2026:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   2027:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   2028:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   2029:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   2030:    * returned function value. 
                   2031:   */
1.126     brouard  2032:   int iter; 
                   2033:   double a,b,d,etemp;
1.159     brouard  2034:   double fu=0,fv,fw,fx;
1.164     brouard  2035:   double ftemp=0.;
1.126     brouard  2036:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   2037:   double e=0.0; 
                   2038:  
                   2039:   a=(ax < cx ? ax : cx); 
                   2040:   b=(ax > cx ? ax : cx); 
                   2041:   x=w=v=bx; 
                   2042:   fw=fv=fx=(*f)(x); 
                   2043:   for (iter=1;iter<=ITMAX;iter++) { 
                   2044:     xm=0.5*(a+b); 
                   2045:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   2046:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   2047:     printf(".");fflush(stdout);
                   2048:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  2049: #ifdef DEBUGBRENT
1.126     brouard  2050:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   2051:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   2052:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   2053: #endif
                   2054:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   2055:       *xmin=x; 
                   2056:       return fx; 
                   2057:     } 
                   2058:     ftemp=fu;
                   2059:     if (fabs(e) > tol1) { 
                   2060:       r=(x-w)*(fx-fv); 
                   2061:       q=(x-v)*(fx-fw); 
                   2062:       p=(x-v)*q-(x-w)*r; 
                   2063:       q=2.0*(q-r); 
                   2064:       if (q > 0.0) p = -p; 
                   2065:       q=fabs(q); 
                   2066:       etemp=e; 
                   2067:       e=d; 
                   2068:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  2069:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  2070:       else { 
1.224     brouard  2071:                                d=p/q; 
                   2072:                                u=x+d; 
                   2073:                                if (u-a < tol2 || b-u < tol2) 
                   2074:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  2075:       } 
                   2076:     } else { 
                   2077:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   2078:     } 
                   2079:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   2080:     fu=(*f)(u); 
                   2081:     if (fu <= fx) { 
                   2082:       if (u >= x) a=x; else b=x; 
                   2083:       SHFT(v,w,x,u) 
1.183     brouard  2084:       SHFT(fv,fw,fx,fu) 
                   2085:     } else { 
                   2086:       if (u < x) a=u; else b=u; 
                   2087:       if (fu <= fw || w == x) { 
1.224     brouard  2088:                                v=w; 
                   2089:                                w=u; 
                   2090:                                fv=fw; 
                   2091:                                fw=fu; 
1.183     brouard  2092:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  2093:                                v=u; 
                   2094:                                fv=fu; 
1.183     brouard  2095:       } 
                   2096:     } 
1.126     brouard  2097:   } 
                   2098:   nrerror("Too many iterations in brent"); 
                   2099:   *xmin=x; 
                   2100:   return fx; 
                   2101: } 
                   2102: 
                   2103: /****************** mnbrak ***********************/
                   2104: 
                   2105: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   2106:            double (*func)(double)) 
1.183     brouard  2107: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   2108: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   2109: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   2110: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   2111:    */
1.126     brouard  2112:   double ulim,u,r,q, dum;
                   2113:   double fu; 
1.187     brouard  2114: 
                   2115:   double scale=10.;
                   2116:   int iterscale=0;
                   2117: 
                   2118:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   2119:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   2120: 
                   2121: 
                   2122:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   2123:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   2124:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   2125:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   2126:   /* } */
                   2127: 
1.126     brouard  2128:   if (*fb > *fa) { 
                   2129:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  2130:     SHFT(dum,*fb,*fa,dum) 
                   2131:   } 
1.126     brouard  2132:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   2133:   *fc=(*func)(*cx); 
1.183     brouard  2134: #ifdef DEBUG
1.224     brouard  2135:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   2136:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  2137: #endif
1.224     brouard  2138:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  2139:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  2140:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  2141:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  2142:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   2143:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   2144:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  2145:       fu=(*func)(u); 
1.163     brouard  2146: #ifdef DEBUG
                   2147:       /* f(x)=A(x-u)**2+f(u) */
                   2148:       double A, fparabu; 
                   2149:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2150:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  2151:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   2152:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  2153:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   2154:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   2155:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   2156:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  2157: #endif 
1.184     brouard  2158: #ifdef MNBRAKORIGINAL
1.183     brouard  2159: #else
1.191     brouard  2160: /*       if (fu > *fc) { */
                   2161: /* #ifdef DEBUG */
                   2162: /*       printf("mnbrak4  fu > fc \n"); */
                   2163: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   2164: /* #endif */
                   2165: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   2166: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   2167: /*     dum=u; /\* Shifting c and u *\/ */
                   2168: /*     u = *cx; */
                   2169: /*     *cx = dum; */
                   2170: /*     dum = fu; */
                   2171: /*     fu = *fc; */
                   2172: /*     *fc =dum; */
                   2173: /*       } else { /\* end *\/ */
                   2174: /* #ifdef DEBUG */
                   2175: /*       printf("mnbrak3  fu < fc \n"); */
                   2176: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2177: /* #endif */
                   2178: /*     dum=u; /\* Shifting c and u *\/ */
                   2179: /*     u = *cx; */
                   2180: /*     *cx = dum; */
                   2181: /*     dum = fu; */
                   2182: /*     fu = *fc; */
                   2183: /*     *fc =dum; */
                   2184: /*       } */
1.224     brouard  2185: #ifdef DEBUGMNBRAK
                   2186:                 double A, fparabu; 
                   2187:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2188:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2189:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2190:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2191: #endif
1.191     brouard  2192:       dum=u; /* Shifting c and u */
                   2193:       u = *cx;
                   2194:       *cx = dum;
                   2195:       dum = fu;
                   2196:       fu = *fc;
                   2197:       *fc =dum;
1.183     brouard  2198: #endif
1.162     brouard  2199:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2200: #ifdef DEBUG
1.224     brouard  2201:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2202:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2203: #endif
1.126     brouard  2204:       fu=(*func)(u); 
                   2205:       if (fu < *fc) { 
1.183     brouard  2206: #ifdef DEBUG
1.224     brouard  2207:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2208:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2209: #endif
                   2210:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2211:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2212: #ifdef DEBUG
                   2213:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2214: #endif
                   2215:       } 
1.162     brouard  2216:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2217: #ifdef DEBUG
1.224     brouard  2218:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2219:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2220: #endif
1.126     brouard  2221:       u=ulim; 
                   2222:       fu=(*func)(u); 
1.183     brouard  2223:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2224: #ifdef DEBUG
1.224     brouard  2225:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2226:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2227: #endif
1.126     brouard  2228:       u=(*cx)+GOLD*(*cx-*bx); 
                   2229:       fu=(*func)(u); 
1.224     brouard  2230: #ifdef DEBUG
                   2231:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2232:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2233: #endif
1.183     brouard  2234:     } /* end tests */
1.126     brouard  2235:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2236:     SHFT(*fa,*fb,*fc,fu) 
                   2237: #ifdef DEBUG
1.224     brouard  2238:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2239:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2240: #endif
                   2241:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2242: } 
                   2243: 
                   2244: /*************** linmin ************************/
1.162     brouard  2245: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2246: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2247: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2248: the value of func at the returned location p . This is actually all accomplished by calling the
                   2249: routines mnbrak and brent .*/
1.126     brouard  2250: int ncom; 
                   2251: double *pcom,*xicom;
                   2252: double (*nrfunc)(double []); 
                   2253:  
1.224     brouard  2254: #ifdef LINMINORIGINAL
1.126     brouard  2255: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2256: #else
                   2257: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2258: #endif
1.126     brouard  2259: { 
                   2260:   double brent(double ax, double bx, double cx, 
                   2261:               double (*f)(double), double tol, double *xmin); 
                   2262:   double f1dim(double x); 
                   2263:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2264:              double *fc, double (*func)(double)); 
                   2265:   int j; 
                   2266:   double xx,xmin,bx,ax; 
                   2267:   double fx,fb,fa;
1.187     brouard  2268: 
1.203     brouard  2269: #ifdef LINMINORIGINAL
                   2270: #else
                   2271:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2272: #endif
                   2273:   
1.126     brouard  2274:   ncom=n; 
                   2275:   pcom=vector(1,n); 
                   2276:   xicom=vector(1,n); 
                   2277:   nrfunc=func; 
                   2278:   for (j=1;j<=n;j++) { 
                   2279:     pcom[j]=p[j]; 
1.202     brouard  2280:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2281:   } 
1.187     brouard  2282: 
1.203     brouard  2283: #ifdef LINMINORIGINAL
                   2284:   xx=1.;
                   2285: #else
                   2286:   axs=0.0;
                   2287:   xxs=1.;
                   2288:   do{
                   2289:     xx= xxs;
                   2290: #endif
1.187     brouard  2291:     ax=0.;
                   2292:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2293:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2294:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2295:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2296:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2297:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2298:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2299: #ifdef LINMINORIGINAL
                   2300: #else
                   2301:     if (fx != fx){
1.224     brouard  2302:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2303:                        printf("|");
                   2304:                        fprintf(ficlog,"|");
1.203     brouard  2305: #ifdef DEBUGLINMIN
1.224     brouard  2306:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2307: #endif
                   2308:     }
1.224     brouard  2309:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2310: #endif
                   2311:   
1.191     brouard  2312: #ifdef DEBUGLINMIN
                   2313:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2314:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2315: #endif
1.224     brouard  2316: #ifdef LINMINORIGINAL
                   2317: #else
1.317     brouard  2318:   if(fb == fx){ /* Flat function in the direction */
                   2319:     xmin=xx;
1.224     brouard  2320:     *flat=1;
1.317     brouard  2321:   }else{
1.224     brouard  2322:     *flat=0;
                   2323: #endif
                   2324:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2325:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2326:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2327:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2328:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2329:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2330: #ifdef DEBUG
1.224     brouard  2331:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2332:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2333: #endif
                   2334: #ifdef LINMINORIGINAL
                   2335: #else
                   2336:                        }
1.126     brouard  2337: #endif
1.191     brouard  2338: #ifdef DEBUGLINMIN
                   2339:   printf("linmin end ");
1.202     brouard  2340:   fprintf(ficlog,"linmin end ");
1.191     brouard  2341: #endif
1.126     brouard  2342:   for (j=1;j<=n;j++) { 
1.203     brouard  2343: #ifdef LINMINORIGINAL
                   2344:     xi[j] *= xmin; 
                   2345: #else
                   2346: #ifdef DEBUGLINMIN
                   2347:     if(xxs <1.0)
                   2348:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2349: #endif
                   2350:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2351: #ifdef DEBUGLINMIN
                   2352:     if(xxs <1.0)
                   2353:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2354: #endif
                   2355: #endif
1.187     brouard  2356:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2357:   } 
1.191     brouard  2358: #ifdef DEBUGLINMIN
1.203     brouard  2359:   printf("\n");
1.191     brouard  2360:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2361:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2362:   for (j=1;j<=n;j++) { 
1.202     brouard  2363:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2364:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2365:     if(j % ncovmodel == 0){
1.191     brouard  2366:       printf("\n");
1.202     brouard  2367:       fprintf(ficlog,"\n");
                   2368:     }
1.191     brouard  2369:   }
1.203     brouard  2370: #else
1.191     brouard  2371: #endif
1.126     brouard  2372:   free_vector(xicom,1,n); 
                   2373:   free_vector(pcom,1,n); 
                   2374: } 
                   2375: 
                   2376: 
                   2377: /*************** powell ************************/
1.162     brouard  2378: /*
1.317     brouard  2379: Minimization of a function func of n variables. Input consists in an initial starting point
                   2380: p[1..n] ; an initial matrix xi[1..n][1..n]  whose columns contain the initial set of di-
                   2381: rections (usually the n unit vectors); and ftol, the fractional tolerance in the function value
                   2382: such that failure to decrease by more than this amount in one iteration signals doneness. On
1.162     brouard  2383: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2384: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2385:  */
1.224     brouard  2386: #ifdef LINMINORIGINAL
                   2387: #else
                   2388:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2389:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2390: #endif
1.126     brouard  2391: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2392:            double (*func)(double [])) 
                   2393: { 
1.224     brouard  2394: #ifdef LINMINORIGINAL
                   2395:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2396:              double (*func)(double [])); 
1.224     brouard  2397: #else 
1.241     brouard  2398:  void linmin(double p[], double xi[], int n, double *fret,
                   2399:             double (*func)(double []),int *flat); 
1.224     brouard  2400: #endif
1.239     brouard  2401:  int i,ibig,j,jk,k; 
1.126     brouard  2402:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2403:   double directest;
1.126     brouard  2404:   double fp,fptt;
                   2405:   double *xits;
                   2406:   int niterf, itmp;
                   2407: 
                   2408:   pt=vector(1,n); 
                   2409:   ptt=vector(1,n); 
                   2410:   xit=vector(1,n); 
                   2411:   xits=vector(1,n); 
                   2412:   *fret=(*func)(p); 
                   2413:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2414:   rcurr_time = time(NULL);  
1.126     brouard  2415:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2416:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2417:     ibig=0; 
                   2418:     del=0.0; 
1.157     brouard  2419:     rlast_time=rcurr_time;
                   2420:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2421:     rcurr_time = time(NULL);  
                   2422:     curr_time = *localtime(&rcurr_time);
                   2423:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2424:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2425: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2426:     for (i=1;i<=n;i++) {
1.126     brouard  2427:       fprintf(ficrespow," %.12lf", p[i]);
                   2428:     }
1.239     brouard  2429:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2430:     printf("\n#model=  1      +     age ");
                   2431:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2432:     if(nagesqr==1){
1.241     brouard  2433:        printf("  + age*age  ");
                   2434:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2435:     }
                   2436:     for(j=1;j <=ncovmodel-2;j++){
                   2437:       if(Typevar[j]==0) {
                   2438:        printf("  +      V%d  ",Tvar[j]);
                   2439:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2440:       }else if(Typevar[j]==1) {
                   2441:        printf("  +    V%d*age ",Tvar[j]);
                   2442:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2443:       }else if(Typevar[j]==2) {
                   2444:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2445:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2446:       }
                   2447:     }
1.126     brouard  2448:     printf("\n");
1.239     brouard  2449: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2450: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2451:     fprintf(ficlog,"\n");
1.239     brouard  2452:     for(i=1,jk=1; i <=nlstate; i++){
                   2453:       for(k=1; k <=(nlstate+ndeath); k++){
                   2454:        if (k != i) {
                   2455:          printf("%d%d ",i,k);
                   2456:          fprintf(ficlog,"%d%d ",i,k);
                   2457:          for(j=1; j <=ncovmodel; j++){
                   2458:            printf("%12.7f ",p[jk]);
                   2459:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2460:            jk++; 
                   2461:          }
                   2462:          printf("\n");
                   2463:          fprintf(ficlog,"\n");
                   2464:        }
                   2465:       }
                   2466:     }
1.241     brouard  2467:     if(*iter <=3 && *iter >1){
1.157     brouard  2468:       tml = *localtime(&rcurr_time);
                   2469:       strcpy(strcurr,asctime(&tml));
                   2470:       rforecast_time=rcurr_time; 
1.126     brouard  2471:       itmp = strlen(strcurr);
                   2472:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2473:        strcurr[itmp-1]='\0';
1.162     brouard  2474:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2475:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2476:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2477:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2478:        forecast_time = *localtime(&rforecast_time);
                   2479:        strcpy(strfor,asctime(&forecast_time));
                   2480:        itmp = strlen(strfor);
                   2481:        if(strfor[itmp-1]=='\n')
                   2482:          strfor[itmp-1]='\0';
                   2483:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2484:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2485:       }
                   2486:     }
1.187     brouard  2487:     for (i=1;i<=n;i++) { /* For each direction i */
                   2488:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2489:       fptt=(*fret); 
                   2490: #ifdef DEBUG
1.203     brouard  2491:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2492:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2493: #endif
1.203     brouard  2494:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2495:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2496: #ifdef LINMINORIGINAL
1.188     brouard  2497:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2498: #else
                   2499:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2500:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2501: #endif
                   2502:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2503:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2504:                                /* because that direction will be replaced unless the gain del is small */
                   2505:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2506:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2507:                                /* with the new direction. */
                   2508:                                del=fabs(fptt-(*fret)); 
                   2509:                                ibig=i; 
1.126     brouard  2510:       } 
                   2511: #ifdef DEBUG
                   2512:       printf("%d %.12e",i,(*fret));
                   2513:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2514:       for (j=1;j<=n;j++) {
1.224     brouard  2515:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2516:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2517:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2518:       }
                   2519:       for(j=1;j<=n;j++) {
1.225     brouard  2520:                                printf(" p(%d)=%.12e",j,p[j]);
                   2521:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2522:       }
                   2523:       printf("\n");
                   2524:       fprintf(ficlog,"\n");
                   2525: #endif
1.187     brouard  2526:     } /* end loop on each direction i */
                   2527:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2528:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2529:     /* New value of last point Pn is not computed, P(n-1) */
1.319     brouard  2530:     for(j=1;j<=n;j++) {
                   2531:       if(flatdir[j] >0){
                   2532:         printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2533:         fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
1.302     brouard  2534:       }
1.319     brouard  2535:       /* printf("\n"); */
                   2536:       /* fprintf(ficlog,"\n"); */
                   2537:     }
1.243     brouard  2538:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2539:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2540:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2541:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2542:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2543:       /* decreased of more than 3.84  */
                   2544:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2545:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2546:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2547:                        
1.188     brouard  2548:       /* Starting the program with initial values given by a former maximization will simply change */
                   2549:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2550:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2551:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2552: #ifdef DEBUG
                   2553:       int k[2],l;
                   2554:       k[0]=1;
                   2555:       k[1]=-1;
                   2556:       printf("Max: %.12e",(*func)(p));
                   2557:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2558:       for (j=1;j<=n;j++) {
                   2559:        printf(" %.12e",p[j]);
                   2560:        fprintf(ficlog," %.12e",p[j]);
                   2561:       }
                   2562:       printf("\n");
                   2563:       fprintf(ficlog,"\n");
                   2564:       for(l=0;l<=1;l++) {
                   2565:        for (j=1;j<=n;j++) {
                   2566:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2567:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2568:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2569:        }
                   2570:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2571:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2572:       }
                   2573: #endif
                   2574: 
                   2575:       free_vector(xit,1,n); 
                   2576:       free_vector(xits,1,n); 
                   2577:       free_vector(ptt,1,n); 
                   2578:       free_vector(pt,1,n); 
                   2579:       return; 
1.192     brouard  2580:     } /* enough precision */ 
1.240     brouard  2581:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2582:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2583:       ptt[j]=2.0*p[j]-pt[j]; 
                   2584:       xit[j]=p[j]-pt[j]; 
                   2585:       pt[j]=p[j]; 
                   2586:     } 
1.181     brouard  2587:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2588: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2589:                if (*iter <=4) {
1.225     brouard  2590: #else
                   2591: #endif
1.224     brouard  2592: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2593: #else
1.161     brouard  2594:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2595: #endif
1.162     brouard  2596:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2597:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2598:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2599:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2600:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2601:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2602:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2603:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2604:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2605:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2606:       /* mu² and del² are equal when f3=f1 */
                   2607:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2608:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2609:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2610:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2611: #ifdef NRCORIGINAL
                   2612:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2613: #else
                   2614:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2615:       t= t- del*SQR(fp-fptt);
1.183     brouard  2616: #endif
1.202     brouard  2617:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2618: #ifdef DEBUG
1.181     brouard  2619:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2620:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2621:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2622:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2623:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2624:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2625:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2626:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2627: #endif
1.183     brouard  2628: #ifdef POWELLORIGINAL
                   2629:       if (t < 0.0) { /* Then we use it for new direction */
                   2630: #else
1.182     brouard  2631:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2632:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2633:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2634:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2635:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2636:       } 
1.181     brouard  2637:       if (directest < 0.0) { /* Then we use it for new direction */
                   2638: #endif
1.191     brouard  2639: #ifdef DEBUGLINMIN
1.234     brouard  2640:        printf("Before linmin in direction P%d-P0\n",n);
                   2641:        for (j=1;j<=n;j++) {
                   2642:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2643:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2644:          if(j % ncovmodel == 0){
                   2645:            printf("\n");
                   2646:            fprintf(ficlog,"\n");
                   2647:          }
                   2648:        }
1.224     brouard  2649: #endif
                   2650: #ifdef LINMINORIGINAL
1.234     brouard  2651:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2652: #else
1.234     brouard  2653:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2654:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2655: #endif
1.234     brouard  2656:        
1.191     brouard  2657: #ifdef DEBUGLINMIN
1.234     brouard  2658:        for (j=1;j<=n;j++) { 
                   2659:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2660:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2661:          if(j % ncovmodel == 0){
                   2662:            printf("\n");
                   2663:            fprintf(ficlog,"\n");
                   2664:          }
                   2665:        }
1.224     brouard  2666: #endif
1.234     brouard  2667:        for (j=1;j<=n;j++) { 
                   2668:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2669:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2670:        }
1.224     brouard  2671: #ifdef LINMINORIGINAL
                   2672: #else
1.234     brouard  2673:        for (j=1, flatd=0;j<=n;j++) {
                   2674:          if(flatdir[j]>0)
                   2675:            flatd++;
                   2676:        }
                   2677:        if(flatd >0){
1.255     brouard  2678:          printf("%d flat directions: ",flatd);
                   2679:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2680:          for (j=1;j<=n;j++) { 
                   2681:            if(flatdir[j]>0){
                   2682:              printf("%d ",j);
                   2683:              fprintf(ficlog,"%d ",j);
                   2684:            }
                   2685:          }
                   2686:          printf("\n");
                   2687:          fprintf(ficlog,"\n");
1.319     brouard  2688: #ifdef FLATSUP
                   2689:           free_vector(xit,1,n); 
                   2690:           free_vector(xits,1,n); 
                   2691:           free_vector(ptt,1,n); 
                   2692:           free_vector(pt,1,n); 
                   2693:           return;
                   2694: #endif
1.234     brouard  2695:        }
1.191     brouard  2696: #endif
1.234     brouard  2697:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2698:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2699:        
1.126     brouard  2700: #ifdef DEBUG
1.234     brouard  2701:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2702:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2703:        for(j=1;j<=n;j++){
                   2704:          printf(" %lf",xit[j]);
                   2705:          fprintf(ficlog," %lf",xit[j]);
                   2706:        }
                   2707:        printf("\n");
                   2708:        fprintf(ficlog,"\n");
1.126     brouard  2709: #endif
1.192     brouard  2710:       } /* end of t or directest negative */
1.224     brouard  2711: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2712: #else
1.234     brouard  2713:       } /* end if (fptt < fp)  */
1.192     brouard  2714: #endif
1.225     brouard  2715: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2716:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2717: #else
1.224     brouard  2718: #endif
1.234     brouard  2719:                } /* loop iteration */ 
1.126     brouard  2720: } 
1.234     brouard  2721:   
1.126     brouard  2722: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2723:   
1.235     brouard  2724:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2725:   {
1.279     brouard  2726:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2727:      *   (and selected quantitative values in nres)
                   2728:      *  by left multiplying the unit
                   2729:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2730:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2731:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2732:      * or prevalence in state 1, prevalence in state 2, 0
                   2733:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2734:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2735:      * Output is prlim.
                   2736:      * Initial matrix pimij 
                   2737:      */
1.206     brouard  2738:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2739:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2740:   /*  0,                   0                  , 1} */
                   2741:   /*
                   2742:    * and after some iteration: */
                   2743:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2744:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2745:   /*  0,                   0                  , 1} */
                   2746:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2747:   /* {0.51571254859325999, 0.4842874514067399, */
                   2748:   /*  0.51326036147820708, 0.48673963852179264} */
                   2749:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2750:     
1.126     brouard  2751:   int i, ii,j,k;
1.209     brouard  2752:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2753:   /* double **matprod2(); */ /* test */
1.218     brouard  2754:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2755:   double **newm;
1.209     brouard  2756:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2757:   int ncvloop=0;
1.288     brouard  2758:   int first=0;
1.169     brouard  2759:   
1.209     brouard  2760:   min=vector(1,nlstate);
                   2761:   max=vector(1,nlstate);
                   2762:   meandiff=vector(1,nlstate);
                   2763: 
1.218     brouard  2764:        /* Starting with matrix unity */
1.126     brouard  2765:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2766:     for (j=1;j<=nlstate+ndeath;j++){
                   2767:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2768:     }
1.169     brouard  2769:   
                   2770:   cov[1]=1.;
                   2771:   
                   2772:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2773:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2774:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2775:     ncvloop++;
1.126     brouard  2776:     newm=savm;
                   2777:     /* Covariates have to be included here again */
1.138     brouard  2778:     cov[2]=agefin;
1.319     brouard  2779:      if(nagesqr==1){
                   2780:       cov[3]= agefin*agefin;
                   2781:      }
1.234     brouard  2782:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2783:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2784:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.319     brouard  2785:       /* cov[++k1]=nbcode[TvarsD[k]][codtabm(ij,k)]; */
1.235     brouard  2786:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2787:     }
                   2788:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2789:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.319     brouard  2790:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k];
                   2791:       /* cov[++k1]=Tqresult[nres][k];  */
1.235     brouard  2792:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2793:     }
1.237     brouard  2794:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.319     brouard  2795:       if(Dummy[Tage[k]]==2){ /* dummy with age */
1.234     brouard  2796:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319     brouard  2797:        /* cov[++k1]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   2798:       } else if(Dummy[Tage[k]]==3){ /* quantitative with age */
                   2799:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k];
                   2800:        /* cov[++k1]=Tqresult[nres][k];  */
1.234     brouard  2801:       }
1.235     brouard  2802:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2803:     }
1.237     brouard  2804:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2805:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2806:       if(Dummy[Tvard[k][1]==0]){
                   2807:        if(Dummy[Tvard[k][2]==0]){
                   2808:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
1.319     brouard  2809:          /* cov[++k1]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.237     brouard  2810:        }else{
                   2811:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
1.319     brouard  2812:          /* cov[++k1]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k]; */
1.237     brouard  2813:        }
                   2814:       }else{
                   2815:        if(Dummy[Tvard[k][2]==0]){
                   2816:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
1.319     brouard  2817:          /* cov[++k1]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]]; */
1.237     brouard  2818:        }else{
                   2819:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
1.319     brouard  2820:          /* cov[++k1]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]]; */
1.237     brouard  2821:        }
                   2822:       }
1.234     brouard  2823:     }
1.138     brouard  2824:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2825:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2826:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2827:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2828:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.319     brouard  2829:     /* age and covariate values of ij are in 'cov' */
1.142     brouard  2830:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2831:     
1.126     brouard  2832:     savm=oldm;
                   2833:     oldm=newm;
1.209     brouard  2834: 
                   2835:     for(j=1; j<=nlstate; j++){
                   2836:       max[j]=0.;
                   2837:       min[j]=1.;
                   2838:     }
                   2839:     for(i=1;i<=nlstate;i++){
                   2840:       sumnew=0;
                   2841:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2842:       for(j=1; j<=nlstate; j++){ 
                   2843:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2844:        max[j]=FMAX(max[j],prlim[i][j]);
                   2845:        min[j]=FMIN(min[j],prlim[i][j]);
                   2846:       }
                   2847:     }
                   2848: 
1.126     brouard  2849:     maxmax=0.;
1.209     brouard  2850:     for(j=1; j<=nlstate; j++){
                   2851:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2852:       maxmax=FMAX(maxmax,meandiff[j]);
                   2853:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2854:     } /* j loop */
1.203     brouard  2855:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2856:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2857:     if(maxmax < ftolpl){
1.209     brouard  2858:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2859:       free_vector(min,1,nlstate);
                   2860:       free_vector(max,1,nlstate);
                   2861:       free_vector(meandiff,1,nlstate);
1.126     brouard  2862:       return prlim;
                   2863:     }
1.288     brouard  2864:   } /* agefin loop */
1.208     brouard  2865:     /* After some age loop it doesn't converge */
1.288     brouard  2866:   if(!first){
                   2867:     first=1;
                   2868:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
1.317     brouard  2869:     fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2870:   }else if (first >=1 && first <10){
                   2871:     fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2872:     first++;
                   2873:   }else if (first ==10){
                   2874:     fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2875:     printf("Warning: the stable prevalence dit not converge. This warning came too often, IMaCh will stop notifying, even in its log file. Look at the graphs to appreciate the non convergence.\n");
                   2876:     fprintf(ficlog,"Warning: the stable prevalence no convergence; too many cases, giving up noticing, even in log file\n");
                   2877:     first++;
1.288     brouard  2878:   }
                   2879: 
1.209     brouard  2880:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2881:   free_vector(min,1,nlstate);
                   2882:   free_vector(max,1,nlstate);
                   2883:   free_vector(meandiff,1,nlstate);
1.208     brouard  2884:   
1.169     brouard  2885:   return prlim; /* should not reach here */
1.126     brouard  2886: }
                   2887: 
1.217     brouard  2888: 
                   2889:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2890: 
1.218     brouard  2891:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2892:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2893:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2894: {
1.264     brouard  2895:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2896:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2897:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2898:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2899:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2900:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2901:   /* Initial matrix pimij */
                   2902:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2903:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2904:   /*  0,                   0                  , 1} */
                   2905:   /*
                   2906:    * and after some iteration: */
                   2907:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2908:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2909:   /*  0,                   0                  , 1} */
                   2910:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2911:   /* {0.51571254859325999, 0.4842874514067399, */
                   2912:   /*  0.51326036147820708, 0.48673963852179264} */
                   2913:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2914: 
                   2915:   int i, ii,j,k;
1.247     brouard  2916:   int first=0;
1.217     brouard  2917:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2918:   /* double **matprod2(); */ /* test */
                   2919:   double **out, cov[NCOVMAX+1], **bmij();
                   2920:   double **newm;
1.218     brouard  2921:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2922:   double        **oldm, **savm;  /* for use */
                   2923: 
1.217     brouard  2924:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2925:   int ncvloop=0;
                   2926:   
                   2927:   min=vector(1,nlstate);
                   2928:   max=vector(1,nlstate);
                   2929:   meandiff=vector(1,nlstate);
                   2930: 
1.266     brouard  2931:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2932:   oldm=oldms; savm=savms;
                   2933:   
                   2934:   /* Starting with matrix unity */
                   2935:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2936:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2937:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2938:     }
                   2939:   
                   2940:   cov[1]=1.;
                   2941:   
                   2942:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2943:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2944:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2945:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2946:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2947:     ncvloop++;
1.218     brouard  2948:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2949:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2950:     /* Covariates have to be included here again */
                   2951:     cov[2]=agefin;
1.319     brouard  2952:     if(nagesqr==1){
1.217     brouard  2953:       cov[3]= agefin*agefin;;
1.319     brouard  2954:     }
1.242     brouard  2955:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2956:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2957:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2958:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2959:     }
                   2960:     /* for (k=1; k<=cptcovn;k++) { */
                   2961:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2962:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2963:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2964:     /* } */
                   2965:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2966:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2967:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2968:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2969:     }
                   2970:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2971:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2972:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2973:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2974:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.319     brouard  2975:       /* if(Dummy[Tvar[Tage[k]]]== 2){ /\* dummy with age *\/ ERROR ???*/
                   2976:       if(Dummy[Tage[k]]== 2){ /* dummy with age */
1.242     brouard  2977:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319     brouard  2978:       } else if(Dummy[Tage[k]]== 3){ /* quantitative with age */
                   2979:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k];
1.242     brouard  2980:       }
                   2981:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2982:     }
                   2983:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2984:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2985:       if(Dummy[Tvard[k][1]==0]){
                   2986:        if(Dummy[Tvard[k][2]==0]){
                   2987:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2988:        }else{
                   2989:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2990:        }
                   2991:       }else{
                   2992:        if(Dummy[Tvard[k][2]==0]){
                   2993:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2994:        }else{
                   2995:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2996:        }
                   2997:       }
1.217     brouard  2998:     }
                   2999:     
                   3000:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   3001:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   3002:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   3003:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3004:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  3005:                /* ij should be linked to the correct index of cov */
                   3006:                /* age and covariate values ij are in 'cov', but we need to pass
                   3007:                 * ij for the observed prevalence at age and status and covariate
                   3008:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   3009:                 */
                   3010:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   3011:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   3012:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  3013:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  3014:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   3015:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   3016:     /*         printf("%d newm= ",i); */
                   3017:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3018:     /*           printf("%f ",newm[i][j]); */
                   3019:     /*         } */
                   3020:     /*         printf("oldm * "); */
                   3021:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3022:     /*           printf("%f ",oldm[i][j]); */
                   3023:     /*         } */
1.268     brouard  3024:     /*         printf(" bmmij "); */
1.266     brouard  3025:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3026:     /*           printf("%f ",pmmij[i][j]); */
                   3027:     /*         } */
                   3028:     /*         printf("\n"); */
                   3029:     /*   } */
                   3030:     /* } */
1.217     brouard  3031:     savm=oldm;
                   3032:     oldm=newm;
1.266     brouard  3033: 
1.217     brouard  3034:     for(j=1; j<=nlstate; j++){
                   3035:       max[j]=0.;
                   3036:       min[j]=1.;
                   3037:     }
                   3038:     for(j=1; j<=nlstate; j++){ 
                   3039:       for(i=1;i<=nlstate;i++){
1.234     brouard  3040:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   3041:        bprlim[i][j]= newm[i][j];
                   3042:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   3043:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  3044:       }
                   3045:     }
1.218     brouard  3046:                
1.217     brouard  3047:     maxmax=0.;
                   3048:     for(i=1; i<=nlstate; i++){
1.318     brouard  3049:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column, could be nan! */
1.217     brouard  3050:       maxmax=FMAX(maxmax,meandiff[i]);
                   3051:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  3052:     } /* i loop */
1.217     brouard  3053:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  3054:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  3055:     if(maxmax < ftolpl){
1.220     brouard  3056:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  3057:       free_vector(min,1,nlstate);
                   3058:       free_vector(max,1,nlstate);
                   3059:       free_vector(meandiff,1,nlstate);
                   3060:       return bprlim;
                   3061:     }
1.288     brouard  3062:   } /* agefin loop */
1.217     brouard  3063:     /* After some age loop it doesn't converge */
1.288     brouard  3064:   if(!first){
1.247     brouard  3065:     first=1;
                   3066:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   3067: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   3068:   }
                   3069:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  3070: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   3071:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   3072:   free_vector(min,1,nlstate);
                   3073:   free_vector(max,1,nlstate);
                   3074:   free_vector(meandiff,1,nlstate);
                   3075:   
                   3076:   return bprlim; /* should not reach here */
                   3077: }
                   3078: 
1.126     brouard  3079: /*************** transition probabilities ***************/ 
                   3080: 
                   3081: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   3082: {
1.138     brouard  3083:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  3084:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  3085:      model to the ncovmodel covariates (including constant and age).
                   3086:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3087:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3088:      ncth covariate in the global vector x is given by the formula:
                   3089:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3090:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3091:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3092:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  3093:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  3094:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  3095:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  3096:   */
                   3097:   double s1, lnpijopii;
1.126     brouard  3098:   /*double t34;*/
1.164     brouard  3099:   int i,j, nc, ii, jj;
1.126     brouard  3100: 
1.223     brouard  3101:   for(i=1; i<= nlstate; i++){
                   3102:     for(j=1; j<i;j++){
                   3103:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3104:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3105:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3106:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3107:       }
                   3108:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3109:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3110:     }
                   3111:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3112:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3113:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3114:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3115:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3116:       }
                   3117:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3118:     }
                   3119:   }
1.218     brouard  3120:   
1.223     brouard  3121:   for(i=1; i<= nlstate; i++){
                   3122:     s1=0;
                   3123:     for(j=1; j<i; j++){
                   3124:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3125:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3126:     }
                   3127:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3128:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3129:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3130:     }
                   3131:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3132:     ps[i][i]=1./(s1+1.);
                   3133:     /* Computing other pijs */
                   3134:     for(j=1; j<i; j++)
                   3135:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3136:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3137:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3138:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3139:   } /* end i */
1.218     brouard  3140:   
1.223     brouard  3141:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3142:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3143:       ps[ii][jj]=0;
                   3144:       ps[ii][ii]=1;
                   3145:     }
                   3146:   }
1.294     brouard  3147: 
                   3148: 
1.223     brouard  3149:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3150:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3151:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3152:   /*   } */
                   3153:   /*   printf("\n "); */
                   3154:   /* } */
                   3155:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3156:   /*
                   3157:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  3158:                goto end;*/
1.266     brouard  3159:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  3160: }
                   3161: 
1.218     brouard  3162: /*************** backward transition probabilities ***************/ 
                   3163: 
                   3164:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3165: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3166:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   3167: {
1.302     brouard  3168:   /* Computes the backward probability at age agefin, cov[2], and covariate combination 'ij'. In fact cov is already filled and x too.
1.266     brouard  3169:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  3170:    */
1.218     brouard  3171:   int i, ii, j,k;
1.222     brouard  3172:   
                   3173:   double **out, **pmij();
                   3174:   double sumnew=0.;
1.218     brouard  3175:   double agefin;
1.292     brouard  3176:   double k3=0.; /* constant of the w_x diagonal matrix (in order for B to sum to 1 even for death state) */
1.222     brouard  3177:   double **dnewm, **dsavm, **doldm;
                   3178:   double **bbmij;
                   3179:   
1.218     brouard  3180:   doldm=ddoldms; /* global pointers */
1.222     brouard  3181:   dnewm=ddnewms;
                   3182:   dsavm=ddsavms;
1.318     brouard  3183: 
                   3184:   /* Debug */
                   3185:   /* printf("Bmij ij=%d, cov[2}=%f\n", ij, cov[2]); */
1.222     brouard  3186:   agefin=cov[2];
1.268     brouard  3187:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3188:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3189:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3190:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3191: 
                   3192:   /* P_x */
1.266     brouard  3193:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  3194:   /* outputs pmmij which is a stochastic matrix in row */
                   3195: 
                   3196:   /* Diag(w_x) */
1.292     brouard  3197:   /* Rescaling the cross-sectional prevalence: Problem with prevacurrent which can be zero */
1.268     brouard  3198:   sumnew=0.;
1.269     brouard  3199:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3200:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.297     brouard  3201:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]); */
1.268     brouard  3202:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3203:   }
                   3204:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3205:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3206:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3207:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3208:     }
                   3209:   }else{
                   3210:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3211:       for (j=1;j<=nlstate+ndeath;j++)
                   3212:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3213:     }
                   3214:     /* if(sumnew <0.9){ */
                   3215:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3216:     /* } */
                   3217:   }
                   3218:   k3=0.0;  /* We put the last diagonal to 0 */
                   3219:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3220:       doldm[ii][ii]= k3;
                   3221:   }
                   3222:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3223:   
1.292     brouard  3224:   /* Left product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm): diag[(w_i)*Px */
                   3225:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* was a Bug Valgrind */
1.268     brouard  3226: 
1.292     brouard  3227:   /* Diag(Sum_i w^i_x p^ij_x, should be the prevalence at age x+stepm */
1.268     brouard  3228:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3229:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3230:     sumnew=0.;
1.222     brouard  3231:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3232:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3233:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3234:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3235:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3236:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3237:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3238:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3239:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3240:        /* }else */
1.268     brouard  3241:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3242:     } /*End ii */
                   3243:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3244: 
1.292     brouard  3245:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* was a Bug Valgrind */
1.268     brouard  3246:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3247:   /* end bmij */
1.266     brouard  3248:   return ps; /*pointer is unchanged */
1.218     brouard  3249: }
1.217     brouard  3250: /*************** transition probabilities ***************/ 
                   3251: 
1.218     brouard  3252: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3253: {
                   3254:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3255:      computes the probability to be observed in state j being in state i by appying the
                   3256:      model to the ncovmodel covariates (including constant and age).
                   3257:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3258:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3259:      ncth covariate in the global vector x is given by the formula:
                   3260:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3261:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3262:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3263:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3264:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3265:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3266:   */
                   3267:   double s1, lnpijopii;
                   3268:   /*double t34;*/
                   3269:   int i,j, nc, ii, jj;
                   3270: 
1.234     brouard  3271:   for(i=1; i<= nlstate; i++){
                   3272:     for(j=1; j<i;j++){
                   3273:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3274:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3275:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3276:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3277:       }
                   3278:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3279:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3280:     }
                   3281:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3282:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3283:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3284:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3285:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3286:       }
                   3287:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3288:     }
                   3289:   }
                   3290:   
                   3291:   for(i=1; i<= nlstate; i++){
                   3292:     s1=0;
                   3293:     for(j=1; j<i; j++){
                   3294:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3295:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3296:     }
                   3297:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3298:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3299:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3300:     }
                   3301:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3302:     ps[i][i]=1./(s1+1.);
                   3303:     /* Computing other pijs */
                   3304:     for(j=1; j<i; j++)
                   3305:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3306:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3307:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3308:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3309:   } /* end i */
                   3310:   
                   3311:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3312:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3313:       ps[ii][jj]=0;
                   3314:       ps[ii][ii]=1;
                   3315:     }
                   3316:   }
1.296     brouard  3317:   /* Added for prevbcast */ /* Transposed matrix too */
1.234     brouard  3318:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3319:     s1=0.;
                   3320:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3321:       s1+=ps[ii][jj];
                   3322:     }
                   3323:     for(ii=1; ii<= nlstate; ii++){
                   3324:       ps[ii][jj]=ps[ii][jj]/s1;
                   3325:     }
                   3326:   }
                   3327:   /* Transposition */
                   3328:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3329:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3330:       s1=ps[ii][jj];
                   3331:       ps[ii][jj]=ps[jj][ii];
                   3332:       ps[jj][ii]=s1;
                   3333:     }
                   3334:   }
                   3335:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3336:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3337:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3338:   /*   } */
                   3339:   /*   printf("\n "); */
                   3340:   /* } */
                   3341:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3342:   /*
                   3343:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3344:     goto end;*/
                   3345:   return ps;
1.217     brouard  3346: }
                   3347: 
                   3348: 
1.126     brouard  3349: /**************** Product of 2 matrices ******************/
                   3350: 
1.145     brouard  3351: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3352: {
                   3353:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3354:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3355:   /* in, b, out are matrice of pointers which should have been initialized 
                   3356:      before: only the contents of out is modified. The function returns
                   3357:      a pointer to pointers identical to out */
1.145     brouard  3358:   int i, j, k;
1.126     brouard  3359:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3360:     for(k=ncolol; k<=ncoloh; k++){
                   3361:       out[i][k]=0.;
                   3362:       for(j=ncl; j<=nch; j++)
                   3363:        out[i][k] +=in[i][j]*b[j][k];
                   3364:     }
1.126     brouard  3365:   return out;
                   3366: }
                   3367: 
                   3368: 
                   3369: /************* Higher Matrix Product ***************/
                   3370: 
1.235     brouard  3371: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3372: {
1.218     brouard  3373:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3374:      'nhstepm*hstepm*stepm' months (i.e. until
                   3375:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3376:      nhstepm*hstepm matrices. 
                   3377:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3378:      (typically every 2 years instead of every month which is too big 
                   3379:      for the memory).
                   3380:      Model is determined by parameters x and covariates have to be 
                   3381:      included manually here. 
                   3382: 
                   3383:      */
                   3384: 
                   3385:   int i, j, d, h, k;
1.131     brouard  3386:   double **out, cov[NCOVMAX+1];
1.126     brouard  3387:   double **newm;
1.187     brouard  3388:   double agexact;
1.214     brouard  3389:   double agebegin, ageend;
1.126     brouard  3390: 
                   3391:   /* Hstepm could be zero and should return the unit matrix */
                   3392:   for (i=1;i<=nlstate+ndeath;i++)
                   3393:     for (j=1;j<=nlstate+ndeath;j++){
                   3394:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3395:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3396:     }
                   3397:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3398:   for(h=1; h <=nhstepm; h++){
                   3399:     for(d=1; d <=hstepm; d++){
                   3400:       newm=savm;
                   3401:       /* Covariates have to be included here again */
                   3402:       cov[1]=1.;
1.214     brouard  3403:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3404:       cov[2]=agexact;
1.319     brouard  3405:       if(nagesqr==1){
1.227     brouard  3406:        cov[3]= agexact*agexact;
1.319     brouard  3407:       }
1.235     brouard  3408:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
1.319     brouard  3409: /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3410:        /* codtabm(ij,k)  (1 & (ij-1) >> (k-1))+1 */
                   3411: /*             V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   3412: /*    k        1  2   3   4     5    6    7     8    9 */
                   3413: /*Tvar[k]=     5  4   3   6     5    2    7     1    1 */
                   3414: /*    nsd         1   2                              3 */ /* Counting single dummies covar fixed or tv */
                   3415: /*TvarsD[nsd]     4   3                              1 */ /* ID of single dummy cova fixed or timevary*/
                   3416: /*TvarsDind[k]    2   3                              9 */ /* position K of single dummy cova */
1.235     brouard  3417:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3418:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3419:       }
                   3420:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3421:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.319     brouard  3422:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k];
1.235     brouard  3423:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3424:       }
1.319     brouard  3425:       for (k=1; k<=cptcovage;k++){ /* For product with age V1+V1*age +V4 +age*V3 */
                   3426:        /* 1+2 Tage[1]=2 TVar[2]=1 Dummy[2]=2, Tage[2]=4 TVar[4]=3 Dummy[4]=3 quant*/
                   3427:        /* */
                   3428:        if(Dummy[Tage[k]]== 2){ /* dummy with age */
                   3429:        /* if(Dummy[Tvar[Tage[k]]]== 2){ /\* dummy with age *\/ */
1.235     brouard  3430:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319     brouard  3431:        } else if(Dummy[Tage[k]]== 3){ /* quantitative with age */
                   3432:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k];
1.235     brouard  3433:        }
                   3434:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3435:       }
1.319     brouard  3436:       for (k=1; k<=cptcovprod;k++){ /*  For product without age */
1.235     brouard  3437:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.319     brouard  3438:        /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   3439:        if(Dummy[Tvard[k][1]==0]){
                   3440:          if(Dummy[Tvard[k][2]==0]){
                   3441:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3442:          }else{
                   3443:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   3444:          }
                   3445:        }else{
                   3446:          if(Dummy[Tvard[k][2]==0]){
                   3447:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   3448:          }else{
                   3449:            cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   3450:          }
                   3451:        }
1.235     brouard  3452:       }
                   3453:       /* for (k=1; k<=cptcovn;k++)  */
                   3454:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3455:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3456:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3457:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3458:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3459:       
                   3460:       
1.126     brouard  3461:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3462:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.319     brouard  3463:       /* right multiplication of oldm by the current matrix */
1.126     brouard  3464:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3465:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3466:       /* if((int)age == 70){ */
                   3467:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3468:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3469:       /*         printf("%d pmmij ",i); */
                   3470:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3471:       /*           printf("%f ",pmmij[i][j]); */
                   3472:       /*         } */
                   3473:       /*         printf(" oldm "); */
                   3474:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3475:       /*           printf("%f ",oldm[i][j]); */
                   3476:       /*         } */
                   3477:       /*         printf("\n"); */
                   3478:       /*       } */
                   3479:       /* } */
1.126     brouard  3480:       savm=oldm;
                   3481:       oldm=newm;
                   3482:     }
                   3483:     for(i=1; i<=nlstate+ndeath; i++)
                   3484:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3485:        po[i][j][h]=newm[i][j];
                   3486:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3487:       }
1.128     brouard  3488:     /*printf("h=%d ",h);*/
1.126     brouard  3489:   } /* end h */
1.267     brouard  3490:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3491:   return po;
                   3492: }
                   3493: 
1.217     brouard  3494: /************* Higher Back Matrix Product ***************/
1.218     brouard  3495: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3496: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3497: {
1.266     brouard  3498:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3499:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3500:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3501:      nhstepm*hstepm matrices.
                   3502:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3503:      (typically every 2 years instead of every month which is too big
1.217     brouard  3504:      for the memory).
1.218     brouard  3505:      Model is determined by parameters x and covariates have to be
1.266     brouard  3506:      included manually here. Then we use a call to bmij(x and cov)
                   3507:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3508:   */
1.217     brouard  3509: 
                   3510:   int i, j, d, h, k;
1.266     brouard  3511:   double **out, cov[NCOVMAX+1], **bmij();
                   3512:   double **newm, ***newmm;
1.217     brouard  3513:   double agexact;
                   3514:   double agebegin, ageend;
1.222     brouard  3515:   double **oldm, **savm;
1.217     brouard  3516: 
1.266     brouard  3517:   newmm=po; /* To be saved */
                   3518:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3519:   /* Hstepm could be zero and should return the unit matrix */
                   3520:   for (i=1;i<=nlstate+ndeath;i++)
                   3521:     for (j=1;j<=nlstate+ndeath;j++){
                   3522:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3523:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3524:     }
                   3525:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3526:   for(h=1; h <=nhstepm; h++){
                   3527:     for(d=1; d <=hstepm; d++){
                   3528:       newm=savm;
                   3529:       /* Covariates have to be included here again */
                   3530:       cov[1]=1.;
1.271     brouard  3531:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3532:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
1.318     brouard  3533:         /* Debug */
                   3534:       /* printf("hBxij age=%lf, agexact=%lf\n", age, agexact); */
1.217     brouard  3535:       cov[2]=agexact;
                   3536:       if(nagesqr==1)
1.222     brouard  3537:        cov[3]= agexact*agexact;
1.266     brouard  3538:       for (k=1; k<=cptcovn;k++){
                   3539:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3540:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3541:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3542:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3543:       }
1.267     brouard  3544:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3545:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3546:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3547:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3548:       }
1.319     brouard  3549:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 *//* For product with age */
                   3550:        /* if(Dummy[Tvar[Tage[k]]]== 2){ /\* dummy with age error!!!*\/ */
                   3551:        if(Dummy[Tage[k]]== 2){ /* dummy with age */
1.267     brouard  3552:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319     brouard  3553:        } else if(Dummy[Tage[k]]== 3){ /* quantitative with age */
1.267     brouard  3554:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3555:        }
                   3556:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3557:       }
                   3558:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3559:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3560:       }                        
1.217     brouard  3561:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3562:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3563: 
1.218     brouard  3564:       /* Careful transposed matrix */
1.266     brouard  3565:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3566:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3567:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3568:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3569:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3570:       /* if((int)age == 70){ */
                   3571:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3572:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3573:       /*         printf("%d pmmij ",i); */
                   3574:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3575:       /*           printf("%f ",pmmij[i][j]); */
                   3576:       /*         } */
                   3577:       /*         printf(" oldm "); */
                   3578:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3579:       /*           printf("%f ",oldm[i][j]); */
                   3580:       /*         } */
                   3581:       /*         printf("\n"); */
                   3582:       /*       } */
                   3583:       /* } */
                   3584:       savm=oldm;
                   3585:       oldm=newm;
                   3586:     }
                   3587:     for(i=1; i<=nlstate+ndeath; i++)
                   3588:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3589:        po[i][j][h]=newm[i][j];
1.268     brouard  3590:        /* if(h==nhstepm) */
                   3591:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3592:       }
1.268     brouard  3593:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3594:   } /* end h */
1.268     brouard  3595:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3596:   return po;
                   3597: }
                   3598: 
                   3599: 
1.162     brouard  3600: #ifdef NLOPT
                   3601:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3602:   double fret;
                   3603:   double *xt;
                   3604:   int j;
                   3605:   myfunc_data *d2 = (myfunc_data *) pd;
                   3606: /* xt = (p1-1); */
                   3607:   xt=vector(1,n); 
                   3608:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3609: 
                   3610:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3611:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3612:   printf("Function = %.12lf ",fret);
                   3613:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3614:   printf("\n");
                   3615:  free_vector(xt,1,n);
                   3616:   return fret;
                   3617: }
                   3618: #endif
1.126     brouard  3619: 
                   3620: /*************** log-likelihood *************/
                   3621: double func( double *x)
                   3622: {
1.226     brouard  3623:   int i, ii, j, k, mi, d, kk;
                   3624:   int ioffset=0;
                   3625:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3626:   double **out;
                   3627:   double lli; /* Individual log likelihood */
                   3628:   int s1, s2;
1.228     brouard  3629:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3630:   double bbh, survp;
                   3631:   long ipmx;
                   3632:   double agexact;
                   3633:   /*extern weight */
                   3634:   /* We are differentiating ll according to initial status */
                   3635:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3636:   /*for(i=1;i<imx;i++) 
                   3637:     printf(" %d\n",s[4][i]);
                   3638:   */
1.162     brouard  3639: 
1.226     brouard  3640:   ++countcallfunc;
1.162     brouard  3641: 
1.226     brouard  3642:   cov[1]=1.;
1.126     brouard  3643: 
1.226     brouard  3644:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3645:   ioffset=0;
1.226     brouard  3646:   if(mle==1){
                   3647:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3648:       /* Computes the values of the ncovmodel covariates of the model
                   3649:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3650:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3651:         to be observed in j being in i according to the model.
                   3652:       */
1.243     brouard  3653:       ioffset=2+nagesqr ;
1.233     brouard  3654:    /* Fixed */
1.319     brouard  3655:       for (k=1; k<=ncovf;k++){ /* For each fixed covariate dummu or quant or prod */
                   3656:        /* # V1=sex, V2=raedyrs Quant Fixed, State=livarnb4..livarnb11, V3=iadl4..iald11, V4=adlw4..adlw11, V5=r4bmi..r11bmi */
                   3657:         /*             V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   3658:        /*  TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  ID of fixed covariates or product V2, V1*V2, V1 */
1.320     brouard  3659:         /* TvarFind;  TvarFind[1]=6,  TvarFind[2]=7, TvarFind[3]=9 *//* Inverse V2(6) is first fixed (single or prod)  */
1.319     brouard  3660:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (TvarFind[1]=6)*/
                   3661:        /* V1*V2 (7)  TvarFind[2]=7, TvarFind[3]=9 */
1.234     brouard  3662:       }
1.226     brouard  3663:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
1.319     brouard  3664:         is 5, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2]=6 
1.226     brouard  3665:         has been calculated etc */
                   3666:       /* For an individual i, wav[i] gives the number of effective waves */
                   3667:       /* We compute the contribution to Likelihood of each effective transition
                   3668:         mw[mi][i] is real wave of the mi th effectve wave */
                   3669:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3670:         s2=s[mw[mi+1][i]][i];
                   3671:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3672:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3673:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3674:       */
                   3675:       for(mi=1; mi<= wav[i]-1; mi++){
1.319     brouard  3676:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates in the model (single and product but no age )"V5+V4+V3+V4*V3+V5*age+V1*age+V1" +TvarVind 1,2,3,4(V4*V3)  Tvar[1]@7{5, 4, 3, 6, 5, 1, 1 ; 6 because the created covar is after V5 and is 6, minus 1+1, 3,2,1,4 positions in cotvar*/
                   3677:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; but where is the crossproduct? */
1.242     brouard  3678:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3679:        }
                   3680:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3681:          for (j=1;j<=nlstate+ndeath;j++){
                   3682:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3683:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3684:          }
                   3685:        for(d=0; d<dh[mi][i]; d++){
                   3686:          newm=savm;
                   3687:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3688:          cov[2]=agexact;
                   3689:          if(nagesqr==1)
                   3690:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3691:          for (kk=1; kk<=cptcovage;kk++) {
1.318     brouard  3692:            if(!FixedV[Tvar[Tage[kk]]])
                   3693:              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
                   3694:            else
                   3695:              cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3696:          }
                   3697:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3698:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3699:          savm=oldm;
                   3700:          oldm=newm;
                   3701:        } /* end mult */
                   3702:        
                   3703:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3704:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3705:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3706:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3707:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3708:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3709:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3710:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3711:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3712:                                 * -stepm/2 to stepm/2 .
                   3713:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3714:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3715:                                 */
1.234     brouard  3716:        s1=s[mw[mi][i]][i];
                   3717:        s2=s[mw[mi+1][i]][i];
                   3718:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3719:        /* bias bh is positive if real duration
                   3720:         * is higher than the multiple of stepm and negative otherwise.
                   3721:         */
                   3722:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3723:        if( s2 > nlstate){ 
                   3724:          /* i.e. if s2 is a death state and if the date of death is known 
                   3725:             then the contribution to the likelihood is the probability to 
                   3726:             die between last step unit time and current  step unit time, 
                   3727:             which is also equal to probability to die before dh 
                   3728:             minus probability to die before dh-stepm . 
                   3729:             In version up to 0.92 likelihood was computed
                   3730:             as if date of death was unknown. Death was treated as any other
                   3731:             health state: the date of the interview describes the actual state
                   3732:             and not the date of a change in health state. The former idea was
                   3733:             to consider that at each interview the state was recorded
                   3734:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3735:             introduced the exact date of death then we should have modified
                   3736:             the contribution of an exact death to the likelihood. This new
                   3737:             contribution is smaller and very dependent of the step unit
                   3738:             stepm. It is no more the probability to die between last interview
                   3739:             and month of death but the probability to survive from last
                   3740:             interview up to one month before death multiplied by the
                   3741:             probability to die within a month. Thanks to Chris
                   3742:             Jackson for correcting this bug.  Former versions increased
                   3743:             mortality artificially. The bad side is that we add another loop
                   3744:             which slows down the processing. The difference can be up to 10%
                   3745:             lower mortality.
                   3746:          */
                   3747:          /* If, at the beginning of the maximization mostly, the
                   3748:             cumulative probability or probability to be dead is
                   3749:             constant (ie = 1) over time d, the difference is equal to
                   3750:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3751:             s1 at precedent wave, to be dead a month before current
                   3752:             wave is equal to probability, being at state s1 at
                   3753:             precedent wave, to be dead at mont of the current
                   3754:             wave. Then the observed probability (that this person died)
                   3755:             is null according to current estimated parameter. In fact,
                   3756:             it should be very low but not zero otherwise the log go to
                   3757:             infinity.
                   3758:          */
1.183     brouard  3759: /* #ifdef INFINITYORIGINAL */
                   3760: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3761: /* #else */
                   3762: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3763: /*         lli=log(mytinydouble); */
                   3764: /*       else */
                   3765: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3766: /* #endif */
1.226     brouard  3767:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3768:          
1.226     brouard  3769:        } else if  ( s2==-1 ) { /* alive */
                   3770:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3771:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3772:          /*survp += out[s1][j]; */
                   3773:          lli= log(survp);
                   3774:        }
                   3775:        else if  (s2==-4) { 
                   3776:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3777:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3778:          lli= log(survp); 
                   3779:        } 
                   3780:        else if  (s2==-5) { 
                   3781:          for (j=1,survp=0. ; j<=2; j++)  
                   3782:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3783:          lli= log(survp); 
                   3784:        } 
                   3785:        else{
                   3786:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3787:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3788:        } 
                   3789:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3790:        /*if(lli ==000.0)*/
                   3791:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3792:        ipmx +=1;
                   3793:        sw += weight[i];
                   3794:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3795:        /* if (lli < log(mytinydouble)){ */
                   3796:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3797:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3798:        /* } */
                   3799:       } /* end of wave */
                   3800:     } /* end of individual */
                   3801:   }  else if(mle==2){
                   3802:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.319     brouard  3803:       ioffset=2+nagesqr ;
                   3804:       for (k=1; k<=ncovf;k++)
                   3805:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];
1.226     brouard  3806:       for(mi=1; mi<= wav[i]-1; mi++){
1.319     brouard  3807:        for(k=1; k <= ncovv ; k++){
                   3808:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3809:        }
1.226     brouard  3810:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3811:          for (j=1;j<=nlstate+ndeath;j++){
                   3812:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3813:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3814:          }
                   3815:        for(d=0; d<=dh[mi][i]; d++){
                   3816:          newm=savm;
                   3817:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3818:          cov[2]=agexact;
                   3819:          if(nagesqr==1)
                   3820:            cov[3]= agexact*agexact;
                   3821:          for (kk=1; kk<=cptcovage;kk++) {
                   3822:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3823:          }
                   3824:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3825:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3826:          savm=oldm;
                   3827:          oldm=newm;
                   3828:        } /* end mult */
                   3829:       
                   3830:        s1=s[mw[mi][i]][i];
                   3831:        s2=s[mw[mi+1][i]][i];
                   3832:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3833:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3834:        ipmx +=1;
                   3835:        sw += weight[i];
                   3836:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3837:       } /* end of wave */
                   3838:     } /* end of individual */
                   3839:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3840:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3841:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3842:       for(mi=1; mi<= wav[i]-1; mi++){
                   3843:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3844:          for (j=1;j<=nlstate+ndeath;j++){
                   3845:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3846:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3847:          }
                   3848:        for(d=0; d<dh[mi][i]; d++){
                   3849:          newm=savm;
                   3850:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3851:          cov[2]=agexact;
                   3852:          if(nagesqr==1)
                   3853:            cov[3]= agexact*agexact;
                   3854:          for (kk=1; kk<=cptcovage;kk++) {
                   3855:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3856:          }
                   3857:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3858:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3859:          savm=oldm;
                   3860:          oldm=newm;
                   3861:        } /* end mult */
                   3862:       
                   3863:        s1=s[mw[mi][i]][i];
                   3864:        s2=s[mw[mi+1][i]][i];
                   3865:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3866:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3867:        ipmx +=1;
                   3868:        sw += weight[i];
                   3869:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3870:       } /* end of wave */
                   3871:     } /* end of individual */
                   3872:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3873:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3874:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3875:       for(mi=1; mi<= wav[i]-1; mi++){
                   3876:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3877:          for (j=1;j<=nlstate+ndeath;j++){
                   3878:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3879:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3880:          }
                   3881:        for(d=0; d<dh[mi][i]; d++){
                   3882:          newm=savm;
                   3883:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3884:          cov[2]=agexact;
                   3885:          if(nagesqr==1)
                   3886:            cov[3]= agexact*agexact;
                   3887:          for (kk=1; kk<=cptcovage;kk++) {
                   3888:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3889:          }
1.126     brouard  3890:        
1.226     brouard  3891:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3892:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3893:          savm=oldm;
                   3894:          oldm=newm;
                   3895:        } /* end mult */
                   3896:       
                   3897:        s1=s[mw[mi][i]][i];
                   3898:        s2=s[mw[mi+1][i]][i];
                   3899:        if( s2 > nlstate){ 
                   3900:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3901:        } else if  ( s2==-1 ) { /* alive */
                   3902:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3903:            survp += out[s1][j];
                   3904:          lli= log(survp);
                   3905:        }else{
                   3906:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3907:        }
                   3908:        ipmx +=1;
                   3909:        sw += weight[i];
                   3910:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3911: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3912:       } /* end of wave */
                   3913:     } /* end of individual */
                   3914:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3915:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3916:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3917:       for(mi=1; mi<= wav[i]-1; mi++){
                   3918:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3919:          for (j=1;j<=nlstate+ndeath;j++){
                   3920:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3921:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3922:          }
                   3923:        for(d=0; d<dh[mi][i]; d++){
                   3924:          newm=savm;
                   3925:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3926:          cov[2]=agexact;
                   3927:          if(nagesqr==1)
                   3928:            cov[3]= agexact*agexact;
                   3929:          for (kk=1; kk<=cptcovage;kk++) {
                   3930:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3931:          }
1.126     brouard  3932:        
1.226     brouard  3933:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3934:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3935:          savm=oldm;
                   3936:          oldm=newm;
                   3937:        } /* end mult */
                   3938:       
                   3939:        s1=s[mw[mi][i]][i];
                   3940:        s2=s[mw[mi+1][i]][i];
                   3941:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3942:        ipmx +=1;
                   3943:        sw += weight[i];
                   3944:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3945:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3946:       } /* end of wave */
                   3947:     } /* end of individual */
                   3948:   } /* End of if */
                   3949:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3950:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3951:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3952:   return -l;
1.126     brouard  3953: }
                   3954: 
                   3955: /*************** log-likelihood *************/
                   3956: double funcone( double *x)
                   3957: {
1.228     brouard  3958:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3959:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3960:   int ioffset=0;
1.131     brouard  3961:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3962:   double **out;
                   3963:   double lli; /* Individual log likelihood */
                   3964:   double llt;
                   3965:   int s1, s2;
1.228     brouard  3966:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3967: 
1.126     brouard  3968:   double bbh, survp;
1.187     brouard  3969:   double agexact;
1.214     brouard  3970:   double agebegin, ageend;
1.126     brouard  3971:   /*extern weight */
                   3972:   /* We are differentiating ll according to initial status */
                   3973:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3974:   /*for(i=1;i<imx;i++) 
                   3975:     printf(" %d\n",s[4][i]);
                   3976:   */
                   3977:   cov[1]=1.;
                   3978: 
                   3979:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3980:   ioffset=0;
                   3981:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3982:     /* ioffset=2+nagesqr+cptcovage; */
                   3983:     ioffset=2+nagesqr;
1.232     brouard  3984:     /* Fixed */
1.224     brouard  3985:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3986:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
1.311     brouard  3987:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products *//* Missing values are set to -1 but should be dropped */
1.232     brouard  3988:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3989: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3990: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3991: /*    cov[2+6]=covar[2][i]; V2  */
                   3992: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3993: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3994: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3995: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3996: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3997: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3998:     }
1.232     brouard  3999:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   4000:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   4001:     /* } */
1.231     brouard  4002:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   4003:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   4004:     /* } */
1.225     brouard  4005:     
1.233     brouard  4006: 
                   4007:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  4008:     /* Wave varying (but not age varying) */
                   4009:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  4010:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   4011:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   4012:       }
1.232     brouard  4013:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  4014:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   4015:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   4016:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   4017:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   4018:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  4019:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  4020:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   4021:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   4022:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  4023:       /* } */
1.126     brouard  4024:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  4025:        for (j=1;j<=nlstate+ndeath;j++){
                   4026:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   4027:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   4028:        }
1.214     brouard  4029:       
                   4030:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   4031:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   4032:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  4033:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  4034:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4035:          and mw[mi+1][i]. dh depends on stepm.*/
                   4036:        newm=savm;
1.247     brouard  4037:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  4038:        cov[2]=agexact;
                   4039:        if(nagesqr==1)
                   4040:          cov[3]= agexact*agexact;
                   4041:        for (kk=1; kk<=cptcovage;kk++) {
                   4042:          if(!FixedV[Tvar[Tage[kk]]])
                   4043:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   4044:          else
                   4045:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   4046:        }
                   4047:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   4048:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   4049:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   4050:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   4051:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   4052:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   4053:        savm=oldm;
                   4054:        oldm=newm;
1.126     brouard  4055:       } /* end mult */
                   4056:       
                   4057:       s1=s[mw[mi][i]][i];
                   4058:       s2=s[mw[mi+1][i]][i];
1.217     brouard  4059:       /* if(s2==-1){ */
1.268     brouard  4060:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  4061:       /*       /\* exit(1); *\/ */
                   4062:       /* } */
1.126     brouard  4063:       bbh=(double)bh[mi][i]/(double)stepm; 
                   4064:       /* bias is positive if real duration
                   4065:        * is higher than the multiple of stepm and negative otherwise.
                   4066:        */
                   4067:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  4068:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  4069:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  4070:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   4071:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   4072:        lli= log(survp);
1.126     brouard  4073:       }else if (mle==1){
1.242     brouard  4074:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  4075:       } else if(mle==2){
1.242     brouard  4076:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  4077:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  4078:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  4079:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  4080:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  4081:       } else{  /* mle=0 back to 1 */
1.242     brouard  4082:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   4083:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  4084:       } /* End of if */
                   4085:       ipmx +=1;
                   4086:       sw += weight[i];
                   4087:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  4088:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  4089:       if(globpr){
1.246     brouard  4090:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  4091:  %11.6f %11.6f %11.6f ", \
1.242     brouard  4092:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  4093:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  4094:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   4095:          llt +=ll[k]*gipmx/gsw;
                   4096:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   4097:        }
                   4098:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  4099:       }
1.232     brouard  4100:        } /* end of wave */
                   4101: } /* end of individual */
                   4102: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   4103: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   4104: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   4105: if(globpr==0){ /* First time we count the contributions and weights */
                   4106:        gipmx=ipmx;
                   4107:        gsw=sw;
                   4108: }
                   4109: return -l;
1.126     brouard  4110: }
                   4111: 
                   4112: 
                   4113: /*************** function likelione ***********/
1.292     brouard  4114: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*func)(double []))
1.126     brouard  4115: {
                   4116:   /* This routine should help understanding what is done with 
                   4117:      the selection of individuals/waves and
                   4118:      to check the exact contribution to the likelihood.
                   4119:      Plotting could be done.
                   4120:    */
                   4121:   int k;
                   4122: 
                   4123:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  4124:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  4125:     strcat(fileresilk,fileresu);
1.126     brouard  4126:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   4127:       printf("Problem with resultfile: %s\n", fileresilk);
                   4128:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   4129:     }
1.214     brouard  4130:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   4131:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  4132:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   4133:     for(k=1; k<=nlstate; k++) 
                   4134:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   4135:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   4136:   }
                   4137: 
1.292     brouard  4138:   *fretone=(*func)(p);
1.126     brouard  4139:   if(*globpri !=0){
                   4140:     fclose(ficresilk);
1.205     brouard  4141:     if (mle ==0)
                   4142:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   4143:     else if(mle >=1)
                   4144:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   4145:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  4146:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  4147:       
                   4148:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  4149:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  4150: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   4151:     }
1.207     brouard  4152:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  4153: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4154:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  4155: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4156:     fflush(fichtm);
1.205     brouard  4157:   }
1.126     brouard  4158:   return;
                   4159: }
                   4160: 
                   4161: 
                   4162: /*********** Maximum Likelihood Estimation ***************/
                   4163: 
                   4164: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   4165: {
1.319     brouard  4166:   int i,j,k, jk, jkk=0, iter=0;
1.126     brouard  4167:   double **xi;
                   4168:   double fret;
                   4169:   double fretone; /* Only one call to likelihood */
                   4170:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  4171: 
                   4172: #ifdef NLOPT
                   4173:   int creturn;
                   4174:   nlopt_opt opt;
                   4175:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   4176:   double *lb;
                   4177:   double minf; /* the minimum objective value, upon return */
                   4178:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   4179:   myfunc_data dinst, *d = &dinst;
                   4180: #endif
                   4181: 
                   4182: 
1.126     brouard  4183:   xi=matrix(1,npar,1,npar);
                   4184:   for (i=1;i<=npar;i++)
                   4185:     for (j=1;j<=npar;j++)
                   4186:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   4187:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  4188:   strcpy(filerespow,"POW_"); 
1.126     brouard  4189:   strcat(filerespow,fileres);
                   4190:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   4191:     printf("Problem with resultfile: %s\n", filerespow);
                   4192:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   4193:   }
                   4194:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   4195:   for (i=1;i<=nlstate;i++)
                   4196:     for(j=1;j<=nlstate+ndeath;j++)
                   4197:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   4198:   fprintf(ficrespow,"\n");
1.162     brouard  4199: #ifdef POWELL
1.319     brouard  4200: #ifdef LINMINORIGINAL
                   4201: #else /* LINMINORIGINAL */
                   4202:   
                   4203:   flatdir=ivector(1,npar); 
                   4204:   for (j=1;j<=npar;j++) flatdir[j]=0; 
                   4205: #endif /*LINMINORIGINAL */
                   4206: 
                   4207: #ifdef FLATSUP
                   4208:   powell(p,xi,npar,ftol,&iter,&fret,flatdir,func);
                   4209:   /* reorganizing p by suppressing flat directions */
                   4210:   for(i=1, jk=1; i <=nlstate; i++){
                   4211:     for(k=1; k <=(nlstate+ndeath); k++){
                   4212:       if (k != i) {
                   4213:         printf("%d%d flatdir[%d]=%d",i,k,jk, flatdir[jk]);
                   4214:         if(flatdir[jk]==1){
                   4215:           printf(" To be skipped %d%d flatdir[%d]=%d ",i,k,jk, flatdir[jk]);
                   4216:         }
                   4217:         for(j=1; j <=ncovmodel; j++){
                   4218:           printf("%12.7f ",p[jk]);
                   4219:           jk++; 
                   4220:         }
                   4221:         printf("\n");
                   4222:       }
                   4223:     }
                   4224:   }
                   4225: /* skipping */
                   4226:   /* for(i=1, jk=1, jkk=1;(flatdir[jk]==0)&& (i <=nlstate); i++){ */
                   4227:   for(i=1, jk=1, jkk=1;i <=nlstate; i++){
                   4228:     for(k=1; k <=(nlstate+ndeath); k++){
                   4229:       if (k != i) {
                   4230:         printf("%d%d flatdir[%d]=%d",i,k,jk, flatdir[jk]);
                   4231:         if(flatdir[jk]==1){
                   4232:           printf(" To be skipped %d%d flatdir[%d]=%d jk=%d p[%d] ",i,k,jk, flatdir[jk],jk, jk);
                   4233:           for(j=1; j <=ncovmodel;  jk++,j++){
                   4234:             printf(" p[%d]=%12.7f",jk, p[jk]);
                   4235:             /*q[jjk]=p[jk];*/
                   4236:           }
                   4237:         }else{
                   4238:           printf(" To be kept %d%d flatdir[%d]=%d jk=%d q[%d]=p[%d] ",i,k,jk, flatdir[jk],jk, jkk, jk);
                   4239:           for(j=1; j <=ncovmodel;  jk++,jkk++,j++){
                   4240:             printf(" p[%d]=%12.7f=q[%d]",jk, p[jk],jkk);
                   4241:             /*q[jjk]=p[jk];*/
                   4242:           }
                   4243:         }
                   4244:         printf("\n");
                   4245:       }
                   4246:       fflush(stdout);
                   4247:     }
                   4248:   }
                   4249:   powell(p,xi,npar,ftol,&iter,&fret,flatdir,func);
                   4250: #else  /* FLATSUP */
1.126     brouard  4251:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.319     brouard  4252: #endif  /* FLATSUP */
                   4253: 
                   4254: #ifdef LINMINORIGINAL
                   4255: #else
                   4256:       free_ivector(flatdir,1,npar); 
                   4257: #endif  /* LINMINORIGINAL*/
                   4258: #endif /* POWELL */
1.126     brouard  4259: 
1.162     brouard  4260: #ifdef NLOPT
                   4261: #ifdef NEWUOA
                   4262:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   4263: #else
                   4264:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   4265: #endif
                   4266:   lb=vector(0,npar-1);
                   4267:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   4268:   nlopt_set_lower_bounds(opt, lb);
                   4269:   nlopt_set_initial_step1(opt, 0.1);
                   4270:   
                   4271:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   4272:   d->function = func;
                   4273:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   4274:   nlopt_set_min_objective(opt, myfunc, d);
                   4275:   nlopt_set_xtol_rel(opt, ftol);
                   4276:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   4277:     printf("nlopt failed! %d\n",creturn); 
                   4278:   }
                   4279:   else {
                   4280:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4281:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4282:     iter=1; /* not equal */
                   4283:   }
                   4284:   nlopt_destroy(opt);
                   4285: #endif
1.319     brouard  4286: #ifdef FLATSUP
                   4287:   /* npared = npar -flatd/ncovmodel; */
                   4288:   /* xired= matrix(1,npared,1,npared); */
                   4289:   /* paramred= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */
                   4290:   /* powell(pred,xired,npared,ftol,&iter,&fret,flatdir,func); */
                   4291:   /* free_matrix(xire,1,npared,1,npared); */
                   4292: #else  /* FLATSUP */
                   4293: #endif /* FLATSUP */
1.126     brouard  4294:   free_matrix(xi,1,npar,1,npar);
                   4295:   fclose(ficrespow);
1.203     brouard  4296:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4297:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4298:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4299: 
                   4300: }
                   4301: 
                   4302: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4303: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4304: {
                   4305:   double  **a,**y,*x,pd;
1.203     brouard  4306:   /* double **hess; */
1.164     brouard  4307:   int i, j;
1.126     brouard  4308:   int *indx;
                   4309: 
                   4310:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4311:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4312:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4313:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4314:   double gompertz(double p[]);
1.203     brouard  4315:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4316: 
                   4317:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4318:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4319:   for (i=1;i<=npar;i++){
1.203     brouard  4320:     printf("%d-",i);fflush(stdout);
                   4321:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4322:    
                   4323:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4324:     
                   4325:     /*  printf(" %f ",p[i]);
                   4326:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4327:   }
                   4328:   
                   4329:   for (i=1;i<=npar;i++) {
                   4330:     for (j=1;j<=npar;j++)  {
                   4331:       if (j>i) { 
1.203     brouard  4332:        printf(".%d-%d",i,j);fflush(stdout);
                   4333:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4334:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4335:        
                   4336:        hess[j][i]=hess[i][j];    
                   4337:        /*printf(" %lf ",hess[i][j]);*/
                   4338:       }
                   4339:     }
                   4340:   }
                   4341:   printf("\n");
                   4342:   fprintf(ficlog,"\n");
                   4343: 
                   4344:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4345:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4346:   
                   4347:   a=matrix(1,npar,1,npar);
                   4348:   y=matrix(1,npar,1,npar);
                   4349:   x=vector(1,npar);
                   4350:   indx=ivector(1,npar);
                   4351:   for (i=1;i<=npar;i++)
                   4352:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4353:   ludcmp(a,npar,indx,&pd);
                   4354: 
                   4355:   for (j=1;j<=npar;j++) {
                   4356:     for (i=1;i<=npar;i++) x[i]=0;
                   4357:     x[j]=1;
                   4358:     lubksb(a,npar,indx,x);
                   4359:     for (i=1;i<=npar;i++){ 
                   4360:       matcov[i][j]=x[i];
                   4361:     }
                   4362:   }
                   4363: 
                   4364:   printf("\n#Hessian matrix#\n");
                   4365:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4366:   for (i=1;i<=npar;i++) { 
                   4367:     for (j=1;j<=npar;j++) { 
1.203     brouard  4368:       printf("%.6e ",hess[i][j]);
                   4369:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4370:     }
                   4371:     printf("\n");
                   4372:     fprintf(ficlog,"\n");
                   4373:   }
                   4374: 
1.203     brouard  4375:   /* printf("\n#Covariance matrix#\n"); */
                   4376:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4377:   /* for (i=1;i<=npar;i++) {  */
                   4378:   /*   for (j=1;j<=npar;j++) {  */
                   4379:   /*     printf("%.6e ",matcov[i][j]); */
                   4380:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4381:   /*   } */
                   4382:   /*   printf("\n"); */
                   4383:   /*   fprintf(ficlog,"\n"); */
                   4384:   /* } */
                   4385: 
1.126     brouard  4386:   /* Recompute Inverse */
1.203     brouard  4387:   /* for (i=1;i<=npar;i++) */
                   4388:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4389:   /* ludcmp(a,npar,indx,&pd); */
                   4390: 
                   4391:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4392: 
                   4393:   /* for (j=1;j<=npar;j++) { */
                   4394:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4395:   /*   x[j]=1; */
                   4396:   /*   lubksb(a,npar,indx,x); */
                   4397:   /*   for (i=1;i<=npar;i++){  */
                   4398:   /*     y[i][j]=x[i]; */
                   4399:   /*     printf("%.3e ",y[i][j]); */
                   4400:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4401:   /*   } */
                   4402:   /*   printf("\n"); */
                   4403:   /*   fprintf(ficlog,"\n"); */
                   4404:   /* } */
                   4405: 
                   4406:   /* Verifying the inverse matrix */
                   4407: #ifdef DEBUGHESS
                   4408:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4409: 
1.203     brouard  4410:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4411:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4412: 
                   4413:   for (j=1;j<=npar;j++) {
                   4414:     for (i=1;i<=npar;i++){ 
1.203     brouard  4415:       printf("%.2f ",y[i][j]);
                   4416:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4417:     }
                   4418:     printf("\n");
                   4419:     fprintf(ficlog,"\n");
                   4420:   }
1.203     brouard  4421: #endif
1.126     brouard  4422: 
                   4423:   free_matrix(a,1,npar,1,npar);
                   4424:   free_matrix(y,1,npar,1,npar);
                   4425:   free_vector(x,1,npar);
                   4426:   free_ivector(indx,1,npar);
1.203     brouard  4427:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4428: 
                   4429: 
                   4430: }
                   4431: 
                   4432: /*************** hessian matrix ****************/
                   4433: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4434: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4435:   int i;
                   4436:   int l=1, lmax=20;
1.203     brouard  4437:   double k1,k2, res, fx;
1.132     brouard  4438:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4439:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4440:   int k=0,kmax=10;
                   4441:   double l1;
                   4442: 
                   4443:   fx=func(x);
                   4444:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4445:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4446:     l1=pow(10,l);
                   4447:     delts=delt;
                   4448:     for(k=1 ; k <kmax; k=k+1){
                   4449:       delt = delta*(l1*k);
                   4450:       p2[theta]=x[theta] +delt;
1.145     brouard  4451:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4452:       p2[theta]=x[theta]-delt;
                   4453:       k2=func(p2)-fx;
                   4454:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4455:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4456:       
1.203     brouard  4457: #ifdef DEBUGHESSII
1.126     brouard  4458:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4459:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4460: #endif
                   4461:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4462:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4463:        k=kmax;
                   4464:       }
                   4465:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4466:        k=kmax; l=lmax*10;
1.126     brouard  4467:       }
                   4468:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4469:        delts=delt;
                   4470:       }
1.203     brouard  4471:     } /* End loop k */
1.126     brouard  4472:   }
                   4473:   delti[theta]=delts;
                   4474:   return res; 
                   4475:   
                   4476: }
                   4477: 
1.203     brouard  4478: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4479: {
                   4480:   int i;
1.164     brouard  4481:   int l=1, lmax=20;
1.126     brouard  4482:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4483:   double p2[MAXPARM+1];
1.203     brouard  4484:   int k, kmax=1;
                   4485:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4486: 
                   4487:   int firstime=0;
1.203     brouard  4488:   
1.126     brouard  4489:   fx=func(x);
1.203     brouard  4490:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4491:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4492:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4493:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4494:     k1=func(p2)-fx;
                   4495:   
1.203     brouard  4496:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4497:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4498:     k2=func(p2)-fx;
                   4499:   
1.203     brouard  4500:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4501:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4502:     k3=func(p2)-fx;
                   4503:   
1.203     brouard  4504:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4505:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4506:     k4=func(p2)-fx;
1.203     brouard  4507:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4508:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4509:       firstime=1;
1.203     brouard  4510:       kmax=kmax+10;
1.208     brouard  4511:     }
                   4512:     if(kmax >=10 || firstime ==1){
1.246     brouard  4513:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4514:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4515:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4516:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4517:     }
                   4518: #ifdef DEBUGHESSIJ
                   4519:     v1=hess[thetai][thetai];
                   4520:     v2=hess[thetaj][thetaj];
                   4521:     cv12=res;
                   4522:     /* Computing eigen value of Hessian matrix */
                   4523:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4524:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4525:     if ((lc2 <0) || (lc1 <0) ){
                   4526:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4527:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4528:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4529:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4530:     }
1.126     brouard  4531: #endif
                   4532:   }
                   4533:   return res;
                   4534: }
                   4535: 
1.203     brouard  4536:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4537: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4538: /* { */
                   4539: /*   int i; */
                   4540: /*   int l=1, lmax=20; */
                   4541: /*   double k1,k2,k3,k4,res,fx; */
                   4542: /*   double p2[MAXPARM+1]; */
                   4543: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4544: /*   int k=0,kmax=10; */
                   4545: /*   double l1; */
                   4546:   
                   4547: /*   fx=func(x); */
                   4548: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4549: /*     l1=pow(10,l); */
                   4550: /*     delts=delt; */
                   4551: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4552: /*       delt = delti*(l1*k); */
                   4553: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4554: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4555: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4556: /*       k1=func(p2)-fx; */
                   4557:       
                   4558: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4559: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4560: /*       k2=func(p2)-fx; */
                   4561:       
                   4562: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4563: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4564: /*       k3=func(p2)-fx; */
                   4565:       
                   4566: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4567: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4568: /*       k4=func(p2)-fx; */
                   4569: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4570: /* #ifdef DEBUGHESSIJ */
                   4571: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4572: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4573: /* #endif */
                   4574: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4575: /*     k=kmax; */
                   4576: /*       } */
                   4577: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4578: /*     k=kmax; l=lmax*10; */
                   4579: /*       } */
                   4580: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4581: /*     delts=delt; */
                   4582: /*       } */
                   4583: /*     } /\* End loop k *\/ */
                   4584: /*   } */
                   4585: /*   delti[theta]=delts; */
                   4586: /*   return res;  */
                   4587: /* } */
                   4588: 
                   4589: 
1.126     brouard  4590: /************** Inverse of matrix **************/
                   4591: void ludcmp(double **a, int n, int *indx, double *d) 
                   4592: { 
                   4593:   int i,imax,j,k; 
                   4594:   double big,dum,sum,temp; 
                   4595:   double *vv; 
                   4596:  
                   4597:   vv=vector(1,n); 
                   4598:   *d=1.0; 
                   4599:   for (i=1;i<=n;i++) { 
                   4600:     big=0.0; 
                   4601:     for (j=1;j<=n;j++) 
                   4602:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4603:     if (big == 0.0){
                   4604:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4605:       for (j=1;j<=n;j++) {
                   4606:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4607:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4608:       }
                   4609:       fflush(ficlog);
                   4610:       fclose(ficlog);
                   4611:       nrerror("Singular matrix in routine ludcmp"); 
                   4612:     }
1.126     brouard  4613:     vv[i]=1.0/big; 
                   4614:   } 
                   4615:   for (j=1;j<=n;j++) { 
                   4616:     for (i=1;i<j;i++) { 
                   4617:       sum=a[i][j]; 
                   4618:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4619:       a[i][j]=sum; 
                   4620:     } 
                   4621:     big=0.0; 
                   4622:     for (i=j;i<=n;i++) { 
                   4623:       sum=a[i][j]; 
                   4624:       for (k=1;k<j;k++) 
                   4625:        sum -= a[i][k]*a[k][j]; 
                   4626:       a[i][j]=sum; 
                   4627:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4628:        big=dum; 
                   4629:        imax=i; 
                   4630:       } 
                   4631:     } 
                   4632:     if (j != imax) { 
                   4633:       for (k=1;k<=n;k++) { 
                   4634:        dum=a[imax][k]; 
                   4635:        a[imax][k]=a[j][k]; 
                   4636:        a[j][k]=dum; 
                   4637:       } 
                   4638:       *d = -(*d); 
                   4639:       vv[imax]=vv[j]; 
                   4640:     } 
                   4641:     indx[j]=imax; 
                   4642:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4643:     if (j != n) { 
                   4644:       dum=1.0/(a[j][j]); 
                   4645:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4646:     } 
                   4647:   } 
                   4648:   free_vector(vv,1,n);  /* Doesn't work */
                   4649: ;
                   4650: } 
                   4651: 
                   4652: void lubksb(double **a, int n, int *indx, double b[]) 
                   4653: { 
                   4654:   int i,ii=0,ip,j; 
                   4655:   double sum; 
                   4656:  
                   4657:   for (i=1;i<=n;i++) { 
                   4658:     ip=indx[i]; 
                   4659:     sum=b[ip]; 
                   4660:     b[ip]=b[i]; 
                   4661:     if (ii) 
                   4662:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4663:     else if (sum) ii=i; 
                   4664:     b[i]=sum; 
                   4665:   } 
                   4666:   for (i=n;i>=1;i--) { 
                   4667:     sum=b[i]; 
                   4668:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4669:     b[i]=sum/a[i][i]; 
                   4670:   } 
                   4671: } 
                   4672: 
                   4673: void pstamp(FILE *fichier)
                   4674: {
1.196     brouard  4675:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4676: }
                   4677: 
1.297     brouard  4678: void date2dmy(double date,double *day, double *month, double *year){
                   4679:   double yp=0., yp1=0., yp2=0.;
                   4680:   
                   4681:   yp1=modf(date,&yp);/* extracts integral of date in yp  and
                   4682:                        fractional in yp1 */
                   4683:   *year=yp;
                   4684:   yp2=modf((yp1*12),&yp);
                   4685:   *month=yp;
                   4686:   yp1=modf((yp2*30.5),&yp);
                   4687:   *day=yp;
                   4688:   if(*day==0) *day=1;
                   4689:   if(*month==0) *month=1;
                   4690: }
                   4691: 
1.253     brouard  4692: 
                   4693: 
1.126     brouard  4694: /************ Frequencies ********************/
1.251     brouard  4695: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4696:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4697:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4698: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4699:   
1.265     brouard  4700:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4701:   int iind=0, iage=0;
                   4702:   int mi; /* Effective wave */
                   4703:   int first;
                   4704:   double ***freq; /* Frequencies */
1.268     brouard  4705:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4706:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4707:   double *meanq, *stdq, *idq;
1.226     brouard  4708:   double **meanqt;
                   4709:   double *pp, **prop, *posprop, *pospropt;
                   4710:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4711:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4712:   double agebegin, ageend;
                   4713:     
                   4714:   pp=vector(1,nlstate);
1.251     brouard  4715:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4716:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4717:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4718:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4719:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4720:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4721:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4722:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4723:   strcpy(fileresp,"P_");
                   4724:   strcat(fileresp,fileresu);
                   4725:   /*strcat(fileresphtm,fileresu);*/
                   4726:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4727:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4728:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4729:     exit(0);
                   4730:   }
1.240     brouard  4731:   
1.226     brouard  4732:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4733:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4734:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4735:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4736:     fflush(ficlog);
                   4737:     exit(70); 
                   4738:   }
                   4739:   else{
                   4740:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4741: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4742: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4743:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4744:   }
1.319     brouard  4745:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies (weight=%d) and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm, weightopt);
1.240     brouard  4746:   
1.226     brouard  4747:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4748:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4749:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4750:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4751:     fflush(ficlog);
                   4752:     exit(70); 
1.240     brouard  4753:   } else{
1.226     brouard  4754:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.319     brouard  4755: ,<hr size=\"2\" color=\"#EC5E5E\"> \n                                  \
1.214     brouard  4756: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4757:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4758:   }
1.319     brouard  4759:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>(weight=%d) frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr,weightopt);
1.240     brouard  4760:   
1.253     brouard  4761:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4762:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4763:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4764:   j1=0;
1.126     brouard  4765:   
1.227     brouard  4766:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4767:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4768:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4769:   
                   4770:   
1.226     brouard  4771:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4772:      reference=low_education V1=0,V2=0
                   4773:      med_educ                V1=1 V2=0, 
                   4774:      high_educ               V1=0 V2=1
                   4775:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4776:   */
1.249     brouard  4777:   dateintsum=0;
                   4778:   k2cpt=0;
                   4779: 
1.253     brouard  4780:   if(cptcoveff == 0 )
1.265     brouard  4781:     nl=1;  /* Constant and age model only */
1.253     brouard  4782:   else
                   4783:     nl=2;
1.265     brouard  4784: 
                   4785:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4786:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4787:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4788:    *     freq[s1][s2][iage] =0.
                   4789:    *     Loop on iind
                   4790:    *       ++freq[s1][s2][iage] weighted
                   4791:    *     end iind
                   4792:    *     if covariate and j!0
                   4793:    *       headers Variable on one line
                   4794:    *     endif cov j!=0
                   4795:    *     header of frequency table by age
                   4796:    *     Loop on age
                   4797:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4798:    *       pos+=freq[s1][s2][iage] weighted
                   4799:    *       Loop on s1 initial state
                   4800:    *         fprintf(ficresp
                   4801:    *       end s1
                   4802:    *     end age
                   4803:    *     if j!=0 computes starting values
                   4804:    *     end compute starting values
                   4805:    *   end j1
                   4806:    * end nl 
                   4807:    */
1.253     brouard  4808:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4809:     if(nj==1)
                   4810:       j=0;  /* First pass for the constant */
1.265     brouard  4811:     else{
1.253     brouard  4812:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4813:     }
1.251     brouard  4814:     first=1;
1.265     brouard  4815:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4816:       posproptt=0.;
                   4817:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4818:        scanf("%d", i);*/
                   4819:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4820:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4821:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4822:            freq[i][s2][m]=0;
1.251     brouard  4823:       
                   4824:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4825:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4826:          prop[i][m]=0;
                   4827:        posprop[i]=0;
                   4828:        pospropt[i]=0;
                   4829:       }
1.283     brouard  4830:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4831:         idq[z1]=0.;
                   4832:         meanq[z1]=0.;
                   4833:         stdq[z1]=0.;
1.283     brouard  4834:       }
                   4835:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4836:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4837:       /*         meanqt[m][z1]=0.; */
                   4838:       /*       } */
                   4839:       /* }       */
1.251     brouard  4840:       /* dateintsum=0; */
                   4841:       /* k2cpt=0; */
                   4842:       
1.265     brouard  4843:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4844:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4845:        bool=1;
                   4846:        if(j !=0){
                   4847:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4848:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4849:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4850:                /* if(Tvaraff[z1] ==-20){ */
                   4851:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4852:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4853:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4854:                /* }else  */
                   4855:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4856:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4857:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4858:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4859:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4860:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4861:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4862:                } /* Onlyf fixed */
                   4863:              } /* end z1 */
                   4864:            } /* cptcovn > 0 */
                   4865:          } /* end any */
                   4866:        }/* end j==0 */
1.265     brouard  4867:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4868:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4869:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4870:            m=mw[mi][iind];
                   4871:            if(j!=0){
                   4872:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4873:                for (z1=1; z1<=cptcoveff; z1++) {
                   4874:                  if( Fixed[Tmodelind[z1]]==1){
                   4875:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4876:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4877:                                                                                      value is -1, we don't select. It differs from the 
                   4878:                                                                                      constant and age model which counts them. */
                   4879:                      bool=0; /* not selected */
                   4880:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4881:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4882:                      bool=0;
                   4883:                    }
                   4884:                  }
                   4885:                }
                   4886:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4887:            } /* end j==0 */
                   4888:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4889:            if(bool==1){ /*Selected */
1.251     brouard  4890:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4891:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4892:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4893:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4894:              if(m >=firstpass && m <=lastpass){
                   4895:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4896:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4897:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4898:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4899:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4900:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4901:                if (m<lastpass) {
                   4902:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4903:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4904:                  if(s[m][iind]==-1)
                   4905:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4906:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.311     brouard  4907:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean on known values only */
                   4908:                    if(!isnan(covar[ncovcol+z1][iind])){
                   4909:                        idq[z1]=idq[z1]+weight[iind];
                   4910:                        meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4911:                        /* stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; *//*error*/
                   4912:                        stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4913:                    }
1.284     brouard  4914:                  }
1.251     brouard  4915:                  /* if((int)agev[m][iind] == 55) */
                   4916:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4917:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4918:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4919:                }
1.251     brouard  4920:              } /* end if between passes */  
                   4921:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4922:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4923:                k2cpt++;
                   4924:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4925:              }
1.251     brouard  4926:            }else{
                   4927:              bool=1;
                   4928:            }/* end bool 2 */
                   4929:          } /* end m */
1.284     brouard  4930:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4931:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4932:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4933:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4934:          /* } */
1.251     brouard  4935:        } /* end bool */
                   4936:       } /* end iind = 1 to imx */
1.319     brouard  4937:       /* prop[s][age] is fed for any initial and valid live state as well as
1.251     brouard  4938:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4939:       
                   4940:       
                   4941:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4942:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4943:         pstamp(ficresp);
1.251     brouard  4944:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4945:         pstamp(ficresp);
1.251     brouard  4946:        printf( "\n#********** Variable "); 
                   4947:        fprintf(ficresp, "\n#********** Variable "); 
                   4948:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4949:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4950:        fprintf(ficlog, "\n#********** Variable "); 
                   4951:        for (z1=1; z1<=cptcoveff; z1++){
                   4952:          if(!FixedV[Tvaraff[z1]]){
                   4953:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4954:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4955:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4956:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4957:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4958:          }else{
1.251     brouard  4959:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4960:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4961:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4962:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4963:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4964:          }
                   4965:        }
                   4966:        printf( "**********\n#");
                   4967:        fprintf(ficresp, "**********\n#");
                   4968:        fprintf(ficresphtm, "**********</h3>\n");
                   4969:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4970:        fprintf(ficlog, "**********\n");
                   4971:       }
1.284     brouard  4972:       /*
                   4973:        Printing means of quantitative variables if any
                   4974:       */
                   4975:       for (z1=1; z1<= nqfveff; z1++) {
1.311     brouard  4976:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.3g (weighted) individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.312     brouard  4977:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
1.284     brouard  4978:        if(weightopt==1){
                   4979:          printf(" Weighted mean and standard deviation of");
                   4980:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4981:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4982:        }
1.311     brouard  4983:        /* mu = \frac{w x}{\sum w}
                   4984:            var = \frac{\sum w (x-mu)^2}{\sum w} = \frac{w x^2}{\sum w} - mu^2 
                   4985:        */
                   4986:        printf(" fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   4987:        fprintf(ficlog," fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   4988:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.3g (weighted) representatives of the population : %8.5g (%8.5g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
1.284     brouard  4989:       }
                   4990:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4991:       /*       for(m=1;m<=lastpass;m++){ */
                   4992:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4993:       /*   } */
                   4994:       /* } */
1.283     brouard  4995: 
1.251     brouard  4996:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4997:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4998:         fprintf(ficresp, " Age");
                   4999:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  5000:       for(i=1; i<=nlstate;i++) {
1.265     brouard  5001:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  5002:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   5003:       }
1.265     brouard  5004:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  5005:       fprintf(ficresphtm, "\n");
                   5006:       
                   5007:       /* Header of frequency table by age */
                   5008:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   5009:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  5010:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  5011:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  5012:          if(s2!=0 && m!=0)
                   5013:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  5014:        }
1.226     brouard  5015:       }
1.251     brouard  5016:       fprintf(ficresphtmfr, "\n");
                   5017:     
                   5018:       /* For each age */
                   5019:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   5020:        fprintf(ficresphtm,"<tr>");
                   5021:        if(iage==iagemax+1){
                   5022:          fprintf(ficlog,"1");
                   5023:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   5024:        }else if(iage==iagemax+2){
                   5025:          fprintf(ficlog,"0");
                   5026:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   5027:        }else if(iage==iagemax+3){
                   5028:          fprintf(ficlog,"Total");
                   5029:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   5030:        }else{
1.240     brouard  5031:          if(first==1){
1.251     brouard  5032:            first=0;
                   5033:            printf("See log file for details...\n");
                   5034:          }
                   5035:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   5036:          fprintf(ficlog,"Age %d", iage);
                   5037:        }
1.265     brouard  5038:        for(s1=1; s1 <=nlstate ; s1++){
                   5039:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   5040:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  5041:        }
1.265     brouard  5042:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  5043:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  5044:            pos += freq[s1][m][iage];
                   5045:          if(pp[s1]>=1.e-10){
1.251     brouard  5046:            if(first==1){
1.265     brouard  5047:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  5048:            }
1.265     brouard  5049:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  5050:          }else{
                   5051:            if(first==1)
1.265     brouard  5052:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   5053:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  5054:          }
                   5055:        }
                   5056:       
1.265     brouard  5057:        for(s1=1; s1 <=nlstate ; s1++){ 
                   5058:          /* posprop[s1]=0; */
                   5059:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   5060:            pp[s1] += freq[s1][m][iage];
                   5061:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   5062:       
                   5063:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   5064:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   5065:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   5066:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   5067:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   5068:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   5069:        }
                   5070:        
                   5071:        /* Writing ficresp */
                   5072:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   5073:           if( iage <= iagemax){
                   5074:            fprintf(ficresp," %d",iage);
                   5075:           }
                   5076:         }else if( nj==2){
                   5077:           if( iage <= iagemax){
                   5078:            fprintf(ficresp," %d",iage);
                   5079:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   5080:           }
1.240     brouard  5081:        }
1.265     brouard  5082:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  5083:          if(pos>=1.e-5){
1.251     brouard  5084:            if(first==1)
1.265     brouard  5085:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   5086:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  5087:          }else{
                   5088:            if(first==1)
1.265     brouard  5089:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   5090:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  5091:          }
                   5092:          if( iage <= iagemax){
                   5093:            if(pos>=1.e-5){
1.265     brouard  5094:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   5095:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   5096:               }else if( nj==2){
                   5097:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   5098:               }
                   5099:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   5100:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   5101:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   5102:            } else{
                   5103:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   5104:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  5105:            }
1.240     brouard  5106:          }
1.265     brouard  5107:          pospropt[s1] +=posprop[s1];
                   5108:        } /* end loop s1 */
1.251     brouard  5109:        /* pospropt=0.; */
1.265     brouard  5110:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  5111:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  5112:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  5113:              if(first==1){
1.265     brouard  5114:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  5115:              }
1.265     brouard  5116:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   5117:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  5118:            }
1.265     brouard  5119:            if(s1!=0 && m!=0)
                   5120:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  5121:          }
1.265     brouard  5122:        } /* end loop s1 */
1.251     brouard  5123:        posproptt=0.; 
1.265     brouard  5124:        for(s1=1; s1 <=nlstate; s1++){
                   5125:          posproptt += pospropt[s1];
1.251     brouard  5126:        }
                   5127:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  5128:        fprintf(ficresphtm,"</tr>\n");
                   5129:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   5130:          if(iage <= iagemax)
                   5131:            fprintf(ficresp,"\n");
1.240     brouard  5132:        }
1.251     brouard  5133:        if(first==1)
                   5134:          printf("Others in log...\n");
                   5135:        fprintf(ficlog,"\n");
                   5136:       } /* end loop age iage */
1.265     brouard  5137:       
1.251     brouard  5138:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  5139:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  5140:        if(posproptt < 1.e-5){
1.265     brouard  5141:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  5142:        }else{
1.265     brouard  5143:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  5144:        }
1.226     brouard  5145:       }
1.251     brouard  5146:       fprintf(ficresphtm,"</tr>\n");
                   5147:       fprintf(ficresphtm,"</table>\n");
                   5148:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  5149:       if(posproptt < 1.e-5){
1.251     brouard  5150:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   5151:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  5152:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   5153:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  5154:        invalidvarcomb[j1]=1;
1.226     brouard  5155:       }else{
1.251     brouard  5156:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   5157:        invalidvarcomb[j1]=0;
1.226     brouard  5158:       }
1.251     brouard  5159:       fprintf(ficresphtmfr,"</table>\n");
                   5160:       fprintf(ficlog,"\n");
                   5161:       if(j!=0){
                   5162:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  5163:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  5164:          for(k=1; k <=(nlstate+ndeath); k++){
                   5165:            if (k != i) {
1.265     brouard  5166:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  5167:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  5168:                  if(j1==1){ /* All dummy covariates to zero */
                   5169:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   5170:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  5171:                    printf("%d%d ",i,k);
                   5172:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  5173:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   5174:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   5175:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  5176:                  }
1.253     brouard  5177:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   5178:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   5179:                    x[iage]= (double)iage;
                   5180:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  5181:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  5182:                  }
1.268     brouard  5183:                  /* Some are not finite, but linreg will ignore these ages */
                   5184:                  no=0;
1.253     brouard  5185:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  5186:                  pstart[s1]=b;
                   5187:                  pstart[s1-1]=a;
1.252     brouard  5188:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   5189:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   5190:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  5191:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  5192:                  printf("%d%d ",i,k);
                   5193:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  5194:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  5195:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   5196:                  ;
                   5197:                }
                   5198:                /* printf("%12.7f )", param[i][jj][k]); */
                   5199:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5200:                s1++; 
1.251     brouard  5201:              } /* end jj */
                   5202:            } /* end k!= i */
                   5203:          } /* end k */
1.265     brouard  5204:        } /* end i, s1 */
1.251     brouard  5205:       } /* end j !=0 */
                   5206:     } /* end selected combination of covariate j1 */
                   5207:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   5208:       printf("#Freqsummary: Starting values for the constants:\n");
                   5209:       fprintf(ficlog,"\n");
1.265     brouard  5210:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  5211:        for(k=1; k <=(nlstate+ndeath); k++){
                   5212:          if (k != i) {
                   5213:            printf("%d%d ",i,k);
                   5214:            fprintf(ficlog,"%d%d ",i,k);
                   5215:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  5216:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  5217:              if(jj==1){ /* Age has to be done */
1.265     brouard  5218:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   5219:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   5220:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  5221:              }
                   5222:              /* printf("%12.7f )", param[i][jj][k]); */
                   5223:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5224:              s1++; 
1.250     brouard  5225:            }
1.251     brouard  5226:            printf("\n");
                   5227:            fprintf(ficlog,"\n");
1.250     brouard  5228:          }
                   5229:        }
1.284     brouard  5230:       } /* end of state i */
1.251     brouard  5231:       printf("#Freqsummary\n");
                   5232:       fprintf(ficlog,"\n");
1.265     brouard  5233:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   5234:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   5235:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   5236:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5237:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5238:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   5239:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   5240:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  5241:          /* } */
                   5242:        }
1.265     brouard  5243:       } /* end loop s1 */
1.251     brouard  5244:       
                   5245:       printf("\n");
                   5246:       fprintf(ficlog,"\n");
                   5247:     } /* end j=0 */
1.249     brouard  5248:   } /* end j */
1.252     brouard  5249: 
1.253     brouard  5250:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  5251:     for(i=1, jk=1; i <=nlstate; i++){
                   5252:       for(j=1; j <=nlstate+ndeath; j++){
                   5253:        if(j!=i){
                   5254:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   5255:          printf("%1d%1d",i,j);
                   5256:          fprintf(ficparo,"%1d%1d",i,j);
                   5257:          for(k=1; k<=ncovmodel;k++){
                   5258:            /*    printf(" %lf",param[i][j][k]); */
                   5259:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   5260:            p[jk]=pstart[jk];
                   5261:            printf(" %f ",pstart[jk]);
                   5262:            fprintf(ficparo," %f ",pstart[jk]);
                   5263:            jk++;
                   5264:          }
                   5265:          printf("\n");
                   5266:          fprintf(ficparo,"\n");
                   5267:        }
                   5268:       }
                   5269:     }
                   5270:   } /* end mle=-2 */
1.226     brouard  5271:   dateintmean=dateintsum/k2cpt; 
1.296     brouard  5272:   date2dmy(dateintmean,&jintmean,&mintmean,&aintmean);
1.240     brouard  5273:   
1.226     brouard  5274:   fclose(ficresp);
                   5275:   fclose(ficresphtm);
                   5276:   fclose(ficresphtmfr);
1.283     brouard  5277:   free_vector(idq,1,nqfveff);
1.226     brouard  5278:   free_vector(meanq,1,nqfveff);
1.284     brouard  5279:   free_vector(stdq,1,nqfveff);
1.226     brouard  5280:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  5281:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   5282:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  5283:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5284:   free_vector(pospropt,1,nlstate);
                   5285:   free_vector(posprop,1,nlstate);
1.251     brouard  5286:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5287:   free_vector(pp,1,nlstate);
                   5288:   /* End of freqsummary */
                   5289: }
1.126     brouard  5290: 
1.268     brouard  5291: /* Simple linear regression */
                   5292: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   5293: 
                   5294:   /* y=a+bx regression */
                   5295:   double   sumx = 0.0;                        /* sum of x                      */
                   5296:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   5297:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   5298:   double   sumy = 0.0;                        /* sum of y                      */
                   5299:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   5300:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   5301:   double yhat;
                   5302:   
                   5303:   double denom=0;
                   5304:   int i;
                   5305:   int ne=*no;
                   5306:   
                   5307:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5308:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5309:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5310:       continue;
                   5311:     }
                   5312:     ne=ne+1;
                   5313:     sumx  += x[i];       
                   5314:     sumx2 += x[i]*x[i];  
                   5315:     sumxy += x[i] * y[i];
                   5316:     sumy  += y[i];      
                   5317:     sumy2 += y[i]*y[i]; 
                   5318:     denom = (ne * sumx2 - sumx*sumx);
                   5319:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5320:   } 
                   5321:   
                   5322:   denom = (ne * sumx2 - sumx*sumx);
                   5323:   if (denom == 0) {
                   5324:     // vertical, slope m is infinity
                   5325:     *b = INFINITY;
                   5326:     *a = 0;
                   5327:     if (r) *r = 0;
                   5328:     return 1;
                   5329:   }
                   5330:   
                   5331:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5332:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5333:   if (r!=NULL) {
                   5334:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5335:       sqrt((sumx2 - sumx*sumx/ne) *
                   5336:           (sumy2 - sumy*sumy/ne));
                   5337:   }
                   5338:   *no=ne;
                   5339:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5340:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5341:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5342:       continue;
                   5343:     }
                   5344:     ne=ne+1;
                   5345:     yhat = y[i] - *a -*b* x[i];
                   5346:     sume2  += yhat * yhat ;       
                   5347:     
                   5348:     denom = (ne * sumx2 - sumx*sumx);
                   5349:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5350:   } 
                   5351:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5352:   *sa= *sb * sqrt(sumx2/ne);
                   5353:   
                   5354:   return 0; 
                   5355: }
                   5356: 
1.126     brouard  5357: /************ Prevalence ********************/
1.227     brouard  5358: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5359: {  
                   5360:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5361:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5362:      We still use firstpass and lastpass as another selection.
                   5363:   */
1.126     brouard  5364:  
1.227     brouard  5365:   int i, m, jk, j1, bool, z1,j, iv;
                   5366:   int mi; /* Effective wave */
                   5367:   int iage;
                   5368:   double agebegin, ageend;
                   5369: 
                   5370:   double **prop;
                   5371:   double posprop; 
                   5372:   double  y2; /* in fractional years */
                   5373:   int iagemin, iagemax;
                   5374:   int first; /** to stop verbosity which is redirected to log file */
                   5375: 
                   5376:   iagemin= (int) agemin;
                   5377:   iagemax= (int) agemax;
                   5378:   /*pp=vector(1,nlstate);*/
1.251     brouard  5379:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5380:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5381:   j1=0;
1.222     brouard  5382:   
1.227     brouard  5383:   /*j=cptcoveff;*/
                   5384:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5385:   
1.288     brouard  5386:   first=0;
1.227     brouard  5387:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5388:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5389:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5390:        prop[i][iage]=0.0;
                   5391:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5392:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5393:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5394:     
                   5395:     for (i=1; i<=imx; i++) { /* Each individual */
                   5396:       bool=1;
                   5397:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5398:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5399:        m=mw[mi][i];
                   5400:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5401:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5402:        for (z1=1; z1<=cptcoveff; z1++){
                   5403:          if( Fixed[Tmodelind[z1]]==1){
                   5404:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5405:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5406:              bool=0;
                   5407:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5408:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5409:              bool=0;
                   5410:            }
                   5411:        }
                   5412:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5413:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5414:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5415:          if(m >=firstpass && m <=lastpass){
                   5416:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5417:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5418:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5419:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5420:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5421:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5422:                exit(1);
                   5423:              }
                   5424:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5425:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5426:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5427:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5428:              } /* end valid statuses */ 
                   5429:            } /* end selection of dates */
                   5430:          } /* end selection of waves */
                   5431:        } /* end bool */
                   5432:       } /* end wave */
                   5433:     } /* end individual */
                   5434:     for(i=iagemin; i <= iagemax+3; i++){  
                   5435:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5436:        posprop += prop[jk][i]; 
                   5437:       } 
                   5438:       
                   5439:       for(jk=1; jk <=nlstate ; jk++){      
                   5440:        if( i <=  iagemax){ 
                   5441:          if(posprop>=1.e-5){ 
                   5442:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5443:          } else{
1.288     brouard  5444:            if(!first){
                   5445:              first=1;
1.266     brouard  5446:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5447:            }else{
1.288     brouard  5448:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5449:            }
                   5450:          }
                   5451:        } 
                   5452:       }/* end jk */ 
                   5453:     }/* end i */ 
1.222     brouard  5454:      /*} *//* end i1 */
1.227     brouard  5455:   } /* end j1 */
1.222     brouard  5456:   
1.227     brouard  5457:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5458:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5459:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5460: }  /* End of prevalence */
1.126     brouard  5461: 
                   5462: /************* Waves Concatenation ***************/
                   5463: 
                   5464: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5465: {
1.298     brouard  5466:   /* Concatenates waves: wav[i] is the number of effective (useful waves in the sense that a non interview is useless) of individual i.
1.126     brouard  5467:      Death is a valid wave (if date is known).
                   5468:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5469:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
1.298     brouard  5470:      and mw[mi+1][i]. dh depends on stepm. s[m][i] exists for any wave from firstpass to lastpass
1.227     brouard  5471:   */
1.126     brouard  5472: 
1.224     brouard  5473:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5474:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5475:      double sum=0., jmean=0.;*/
1.224     brouard  5476:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5477:   int j, k=0,jk, ju, jl;
                   5478:   double sum=0.;
                   5479:   first=0;
1.214     brouard  5480:   firstwo=0;
1.217     brouard  5481:   firsthree=0;
1.218     brouard  5482:   firstfour=0;
1.164     brouard  5483:   jmin=100000;
1.126     brouard  5484:   jmax=-1;
                   5485:   jmean=0.;
1.224     brouard  5486: 
                   5487: /* Treating live states */
1.214     brouard  5488:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5489:     mi=0;  /* First valid wave */
1.227     brouard  5490:     mli=0; /* Last valid wave */
1.309     brouard  5491:     m=firstpass;  /* Loop on waves */
                   5492:     while(s[m][i] <= nlstate){  /* a live state or unknown state  */
1.227     brouard  5493:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5494:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5495:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
1.309     brouard  5496:        mw[++mi][i]=m; /* Valid wave: incrementing mi and updating mi; mw[mi] is the wave number of mi_th valid transition   */
1.227     brouard  5497:        mli=m;
1.224     brouard  5498:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5499:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5500:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5501:       }
1.309     brouard  5502:       else{ /* m = lastpass, eventual special issue with warning */
1.224     brouard  5503: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5504:        break;
1.224     brouard  5505: #else
1.317     brouard  5506:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){ /* no death date and known date of interview, case -2 (vital status unknown is warned later */
1.227     brouard  5507:          if(firsthree == 0){
1.302     brouard  5508:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5509:            firsthree=1;
1.317     brouard  5510:          }else if(firsthree >=1 && firsthree < 10){
                   5511:            fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
                   5512:            firsthree++;
                   5513:          }else if(firsthree == 10){
                   5514:            printf("Information, too many Information flags: no more reported to log either\n");
                   5515:            fprintf(ficlog,"Information, too many Information flags: no more reported to log either\n");
                   5516:            firsthree++;
                   5517:          }else{
                   5518:            firsthree++;
1.227     brouard  5519:          }
1.309     brouard  5520:          mw[++mi][i]=m; /* Valid transition with unknown status */
1.227     brouard  5521:          mli=m;
                   5522:        }
                   5523:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5524:          nbwarn++;
1.309     brouard  5525:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified?not a transition */
1.227     brouard  5526:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5527:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5528:          }
                   5529:          break;
                   5530:        }
                   5531:        break;
1.224     brouard  5532: #endif
1.227     brouard  5533:       }/* End m >= lastpass */
1.126     brouard  5534:     }/* end while */
1.224     brouard  5535: 
1.227     brouard  5536:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5537:     /* After last pass */
1.224     brouard  5538: /* Treating death states */
1.214     brouard  5539:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5540:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5541:       /* } */
1.126     brouard  5542:       mi++;    /* Death is another wave */
                   5543:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5544:       /* Only death is a correct wave */
1.126     brouard  5545:       mw[mi][i]=m;
1.257     brouard  5546:     } /* else not in a death state */
1.224     brouard  5547: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5548:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5549:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.309     brouard  5550:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* month of death occured before last wave month and status should have been death instead of -1 */
1.227     brouard  5551:          nbwarn++;
                   5552:          if(firstfiv==0){
1.309     brouard  5553:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5554:            firstfiv=1;
                   5555:          }else{
1.309     brouard  5556:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5557:          }
1.309     brouard  5558:            s[m][i]=nlstate+1; /* Fixing the status as death. Be careful if multiple death states */
                   5559:        }else{ /* Month of Death occured afer last wave month, potential bias */
1.227     brouard  5560:          nberr++;
                   5561:          if(firstwo==0){
1.309     brouard  5562:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5563:            firstwo=1;
                   5564:          }
1.309     brouard  5565:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5566:        }
1.257     brouard  5567:       }else{ /* if date of interview is unknown */
1.227     brouard  5568:        /* death is known but not confirmed by death status at any wave */
                   5569:        if(firstfour==0){
1.309     brouard  5570:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5571:          firstfour=1;
                   5572:        }
1.309     brouard  5573:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d  with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.214     brouard  5574:       }
1.224     brouard  5575:     } /* end if date of death is known */
                   5576: #endif
1.309     brouard  5577:     wav[i]=mi; /* mi should be the last effective wave (or mli),  */
                   5578:     /* wav[i]=mw[mi][i];   */
1.126     brouard  5579:     if(mi==0){
                   5580:       nbwarn++;
                   5581:       if(first==0){
1.227     brouard  5582:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5583:        first=1;
1.126     brouard  5584:       }
                   5585:       if(first==1){
1.227     brouard  5586:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5587:       }
                   5588:     } /* end mi==0 */
                   5589:   } /* End individuals */
1.214     brouard  5590:   /* wav and mw are no more changed */
1.223     brouard  5591:        
1.317     brouard  5592:   printf("Information, you have to check %d informations which haven't been logged!\n",firsthree);
                   5593:   fprintf(ficlog,"Information, you have to check %d informations which haven't been logged!\n",firsthree);
                   5594: 
                   5595: 
1.126     brouard  5596:   for(i=1; i<=imx; i++){
                   5597:     for(mi=1; mi<wav[i];mi++){
                   5598:       if (stepm <=0)
1.227     brouard  5599:        dh[mi][i]=1;
1.126     brouard  5600:       else{
1.260     brouard  5601:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5602:          if (agedc[i] < 2*AGESUP) {
                   5603:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5604:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5605:            else if(j<0){
                   5606:              nberr++;
                   5607:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5608:              j=1; /* Temporary Dangerous patch */
                   5609:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5610:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5611:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5612:            }
                   5613:            k=k+1;
                   5614:            if (j >= jmax){
                   5615:              jmax=j;
                   5616:              ijmax=i;
                   5617:            }
                   5618:            if (j <= jmin){
                   5619:              jmin=j;
                   5620:              ijmin=i;
                   5621:            }
                   5622:            sum=sum+j;
                   5623:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5624:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5625:          }
                   5626:        }
                   5627:        else{
                   5628:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5629: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5630:                                        
1.227     brouard  5631:          k=k+1;
                   5632:          if (j >= jmax) {
                   5633:            jmax=j;
                   5634:            ijmax=i;
                   5635:          }
                   5636:          else if (j <= jmin){
                   5637:            jmin=j;
                   5638:            ijmin=i;
                   5639:          }
                   5640:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5641:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5642:          if(j<0){
                   5643:            nberr++;
                   5644:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5645:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5646:          }
                   5647:          sum=sum+j;
                   5648:        }
                   5649:        jk= j/stepm;
                   5650:        jl= j -jk*stepm;
                   5651:        ju= j -(jk+1)*stepm;
                   5652:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5653:          if(jl==0){
                   5654:            dh[mi][i]=jk;
                   5655:            bh[mi][i]=0;
                   5656:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5657:                  * to avoid the price of an extra matrix product in likelihood */
                   5658:            dh[mi][i]=jk+1;
                   5659:            bh[mi][i]=ju;
                   5660:          }
                   5661:        }else{
                   5662:          if(jl <= -ju){
                   5663:            dh[mi][i]=jk;
                   5664:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5665:                                 * is higher than the multiple of stepm and negative otherwise.
                   5666:                                 */
                   5667:          }
                   5668:          else{
                   5669:            dh[mi][i]=jk+1;
                   5670:            bh[mi][i]=ju;
                   5671:          }
                   5672:          if(dh[mi][i]==0){
                   5673:            dh[mi][i]=1; /* At least one step */
                   5674:            bh[mi][i]=ju; /* At least one step */
                   5675:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5676:          }
                   5677:        } /* end if mle */
1.126     brouard  5678:       }
                   5679:     } /* end wave */
                   5680:   }
                   5681:   jmean=sum/k;
                   5682:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5683:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5684: }
1.126     brouard  5685: 
                   5686: /*********** Tricode ****************************/
1.220     brouard  5687:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5688:  {
                   5689:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5690:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5691:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5692:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5693:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5694:     */
1.130     brouard  5695: 
1.242     brouard  5696:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5697:    int modmaxcovj=0; /* Modality max of covariates j */
                   5698:    int cptcode=0; /* Modality max of covariates j */
                   5699:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5700: 
                   5701: 
1.242     brouard  5702:    /* cptcoveff=0;  */
                   5703:    /* *cptcov=0; */
1.126     brouard  5704:  
1.242     brouard  5705:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5706:    for (k=1; k <= maxncov; k++)
                   5707:      for(j=1; j<=2; j++)
                   5708:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5709: 
1.242     brouard  5710:    /* Loop on covariates without age and products and no quantitative variable */
                   5711:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5712:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5713:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5714:        switch(Fixed[k]) {
                   5715:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
1.311     brouard  5716:         modmaxcovj=0;
                   5717:         modmincovj=0;
1.242     brouard  5718:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5719:           ij=(int)(covar[Tvar[k]][i]);
                   5720:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5721:            * If product of Vn*Vm, still boolean *:
                   5722:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5723:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5724:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5725:              modality of the nth covariate of individual i. */
                   5726:           if (ij > modmaxcovj)
                   5727:             modmaxcovj=ij; 
                   5728:           else if (ij < modmincovj) 
                   5729:             modmincovj=ij; 
1.287     brouard  5730:           if (ij <0 || ij >1 ){
1.311     brouard  5731:             printf("ERROR, IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5732:             fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5733:             fflush(ficlog);
                   5734:             exit(1);
1.287     brouard  5735:           }
                   5736:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5737:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5738:             exit(1);
                   5739:           }else
                   5740:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5741:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5742:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5743:           /* getting the maximum value of the modality of the covariate
                   5744:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5745:              female ies 1, then modmaxcovj=1.
                   5746:           */
                   5747:         } /* end for loop on individuals i */
                   5748:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5749:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5750:         cptcode=modmaxcovj;
                   5751:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5752:         /*for (i=0; i<=cptcode; i++) {*/
                   5753:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5754:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5755:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5756:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5757:             if( j != -1){
                   5758:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5759:                                  covariate for which somebody answered excluding 
                   5760:                                  undefined. Usually 2: 0 and 1. */
                   5761:             }
                   5762:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5763:                                     covariate for which somebody answered including 
                   5764:                                     undefined. Usually 3: -1, 0 and 1. */
                   5765:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5766:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5767:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5768:                        
1.242     brouard  5769:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5770:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5771:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5772:         /* modmincovj=3; modmaxcovj = 7; */
                   5773:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5774:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5775:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5776:         /* nbcode[Tvar[j]][ij]=k; */
                   5777:         /* nbcode[Tvar[j]][1]=0; */
                   5778:         /* nbcode[Tvar[j]][2]=1; */
                   5779:         /* nbcode[Tvar[j]][3]=2; */
                   5780:         /* To be continued (not working yet). */
                   5781:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5782: 
                   5783:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5784:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5785:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5786:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5787:         /*, could be restored in the future */
                   5788:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5789:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5790:             break;
                   5791:           }
                   5792:           ij++;
1.287     brouard  5793:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5794:           cptcode = ij; /* New max modality for covar j */
                   5795:         } /* end of loop on modality i=-1 to 1 or more */
                   5796:         break;
                   5797:        case 1: /* Testing on varying covariate, could be simple and
                   5798:                * should look at waves or product of fixed *
                   5799:                * varying. No time to test -1, assuming 0 and 1 only */
                   5800:         ij=0;
                   5801:         for(i=0; i<=1;i++){
                   5802:           nbcode[Tvar[k]][++ij]=i;
                   5803:         }
                   5804:         break;
                   5805:        default:
                   5806:         break;
                   5807:        } /* end switch */
                   5808:      } /* end dummy test */
1.311     brouard  5809:      if(Dummy[k]==1 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5810:        for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5811:         if(isnan(covar[Tvar[k]][i])){
                   5812:           printf("ERROR, IMaCh doesn't treat fixed quantitative covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5813:           fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5814:           fflush(ficlog);
                   5815:           exit(1);
                   5816:          }
                   5817:        }
                   5818:      }
1.287     brouard  5819:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5820:   
                   5821:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5822:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5823:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5824:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5825:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5826:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5827:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5828:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5829:   
                   5830:    ij=0;
                   5831:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5832:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5833:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5834:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5835:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5836:        /* If product not in single variable we don't print results */
                   5837:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5838:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5839:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5840:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5841:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5842:        if(Fixed[k]!=0)
                   5843:         anyvaryingduminmodel=1;
                   5844:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5845:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5846:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5847:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5848:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5849:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5850:      } 
                   5851:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5852:    /* ij--; */
                   5853:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5854:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5855:                * because they can be excluded from the model and real
                   5856:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5857:    for(j=ij+1; j<= cptcovt; j++){
                   5858:      Tvaraff[j]=0;
                   5859:      Tmodelind[j]=0;
                   5860:    }
                   5861:    for(j=ntveff+1; j<= cptcovt; j++){
                   5862:      TmodelInvind[j]=0;
                   5863:    }
                   5864:    /* To be sorted */
                   5865:    ;
                   5866:  }
1.126     brouard  5867: 
1.145     brouard  5868: 
1.126     brouard  5869: /*********** Health Expectancies ****************/
                   5870: 
1.235     brouard  5871:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5872: 
                   5873: {
                   5874:   /* Health expectancies, no variances */
1.164     brouard  5875:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5876:   int nhstepma, nstepma; /* Decreasing with age */
                   5877:   double age, agelim, hf;
                   5878:   double ***p3mat;
                   5879:   double eip;
                   5880: 
1.238     brouard  5881:   /* pstamp(ficreseij); */
1.126     brouard  5882:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5883:   fprintf(ficreseij,"# Age");
                   5884:   for(i=1; i<=nlstate;i++){
                   5885:     for(j=1; j<=nlstate;j++){
                   5886:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5887:     }
                   5888:     fprintf(ficreseij," e%1d. ",i);
                   5889:   }
                   5890:   fprintf(ficreseij,"\n");
                   5891: 
                   5892:   
                   5893:   if(estepm < stepm){
                   5894:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5895:   }
                   5896:   else  hstepm=estepm;   
                   5897:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5898:    * This is mainly to measure the difference between two models: for example
                   5899:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5900:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5901:    * progression in between and thus overestimating or underestimating according
                   5902:    * to the curvature of the survival function. If, for the same date, we 
                   5903:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5904:    * to compare the new estimate of Life expectancy with the same linear 
                   5905:    * hypothesis. A more precise result, taking into account a more precise
                   5906:    * curvature will be obtained if estepm is as small as stepm. */
                   5907: 
                   5908:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5909:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5910:      nhstepm is the number of hstepm from age to agelim 
                   5911:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5912:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5913:      and note for a fixed period like estepm months */
                   5914:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5915:      survival function given by stepm (the optimization length). Unfortunately it
                   5916:      means that if the survival funtion is printed only each two years of age and if
                   5917:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5918:      results. So we changed our mind and took the option of the best precision.
                   5919:   */
                   5920:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5921: 
                   5922:   agelim=AGESUP;
                   5923:   /* If stepm=6 months */
                   5924:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5925:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5926:     
                   5927: /* nhstepm age range expressed in number of stepm */
                   5928:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5929:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5930:   /* if (stepm >= YEARM) hstepm=1;*/
                   5931:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5932:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5933: 
                   5934:   for (age=bage; age<=fage; age ++){ 
                   5935:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5936:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5937:     /* if (stepm >= YEARM) hstepm=1;*/
                   5938:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5939: 
                   5940:     /* If stepm=6 months */
                   5941:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5942:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5943:     
1.235     brouard  5944:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5945:     
                   5946:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5947:     
                   5948:     printf("%d|",(int)age);fflush(stdout);
                   5949:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5950:     
                   5951:     /* Computing expectancies */
                   5952:     for(i=1; i<=nlstate;i++)
                   5953:       for(j=1; j<=nlstate;j++)
                   5954:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5955:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5956:          
                   5957:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5958: 
                   5959:        }
                   5960: 
                   5961:     fprintf(ficreseij,"%3.0f",age );
                   5962:     for(i=1; i<=nlstate;i++){
                   5963:       eip=0;
                   5964:       for(j=1; j<=nlstate;j++){
                   5965:        eip +=eij[i][j][(int)age];
                   5966:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5967:       }
                   5968:       fprintf(ficreseij,"%9.4f", eip );
                   5969:     }
                   5970:     fprintf(ficreseij,"\n");
                   5971:     
                   5972:   }
                   5973:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5974:   printf("\n");
                   5975:   fprintf(ficlog,"\n");
                   5976:   
                   5977: }
                   5978: 
1.235     brouard  5979:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5980: 
                   5981: {
                   5982:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5983:      to initial status i, ei. .
1.126     brouard  5984:   */
                   5985:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5986:   int nhstepma, nstepma; /* Decreasing with age */
                   5987:   double age, agelim, hf;
                   5988:   double ***p3matp, ***p3matm, ***varhe;
                   5989:   double **dnewm,**doldm;
                   5990:   double *xp, *xm;
                   5991:   double **gp, **gm;
                   5992:   double ***gradg, ***trgradg;
                   5993:   int theta;
                   5994: 
                   5995:   double eip, vip;
                   5996: 
                   5997:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5998:   xp=vector(1,npar);
                   5999:   xm=vector(1,npar);
                   6000:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   6001:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   6002:   
                   6003:   pstamp(ficresstdeij);
                   6004:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   6005:   fprintf(ficresstdeij,"# Age");
                   6006:   for(i=1; i<=nlstate;i++){
                   6007:     for(j=1; j<=nlstate;j++)
                   6008:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   6009:     fprintf(ficresstdeij," e%1d. ",i);
                   6010:   }
                   6011:   fprintf(ficresstdeij,"\n");
                   6012: 
                   6013:   pstamp(ficrescveij);
                   6014:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   6015:   fprintf(ficrescveij,"# Age");
                   6016:   for(i=1; i<=nlstate;i++)
                   6017:     for(j=1; j<=nlstate;j++){
                   6018:       cptj= (j-1)*nlstate+i;
                   6019:       for(i2=1; i2<=nlstate;i2++)
                   6020:        for(j2=1; j2<=nlstate;j2++){
                   6021:          cptj2= (j2-1)*nlstate+i2;
                   6022:          if(cptj2 <= cptj)
                   6023:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   6024:        }
                   6025:     }
                   6026:   fprintf(ficrescveij,"\n");
                   6027:   
                   6028:   if(estepm < stepm){
                   6029:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   6030:   }
                   6031:   else  hstepm=estepm;   
                   6032:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   6033:    * This is mainly to measure the difference between two models: for example
                   6034:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   6035:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   6036:    * progression in between and thus overestimating or underestimating according
                   6037:    * to the curvature of the survival function. If, for the same date, we 
                   6038:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   6039:    * to compare the new estimate of Life expectancy with the same linear 
                   6040:    * hypothesis. A more precise result, taking into account a more precise
                   6041:    * curvature will be obtained if estepm is as small as stepm. */
                   6042: 
                   6043:   /* For example we decided to compute the life expectancy with the smallest unit */
                   6044:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6045:      nhstepm is the number of hstepm from age to agelim 
                   6046:      nstepm is the number of stepm from age to agelin. 
                   6047:      Look at hpijx to understand the reason of that which relies in memory size
                   6048:      and note for a fixed period like estepm months */
                   6049:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   6050:      survival function given by stepm (the optimization length). Unfortunately it
                   6051:      means that if the survival funtion is printed only each two years of age and if
                   6052:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6053:      results. So we changed our mind and took the option of the best precision.
                   6054:   */
                   6055:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6056: 
                   6057:   /* If stepm=6 months */
                   6058:   /* nhstepm age range expressed in number of stepm */
                   6059:   agelim=AGESUP;
                   6060:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   6061:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   6062:   /* if (stepm >= YEARM) hstepm=1;*/
                   6063:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6064:   
                   6065:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6066:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6067:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   6068:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   6069:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   6070:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   6071: 
                   6072:   for (age=bage; age<=fage; age ++){ 
                   6073:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   6074:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   6075:     /* if (stepm >= YEARM) hstepm=1;*/
                   6076:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  6077:                
1.126     brouard  6078:     /* If stepm=6 months */
                   6079:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   6080:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   6081:     
                   6082:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  6083:                
1.126     brouard  6084:     /* Computing  Variances of health expectancies */
                   6085:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   6086:        decrease memory allocation */
                   6087:     for(theta=1; theta <=npar; theta++){
                   6088:       for(i=1; i<=npar; i++){ 
1.222     brouard  6089:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6090:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  6091:       }
1.235     brouard  6092:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   6093:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  6094:                        
1.126     brouard  6095:       for(j=1; j<= nlstate; j++){
1.222     brouard  6096:        for(i=1; i<=nlstate; i++){
                   6097:          for(h=0; h<=nhstepm-1; h++){
                   6098:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   6099:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   6100:          }
                   6101:        }
1.126     brouard  6102:       }
1.218     brouard  6103:                        
1.126     brouard  6104:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  6105:        for(h=0; h<=nhstepm-1; h++){
                   6106:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   6107:        }
1.126     brouard  6108:     }/* End theta */
                   6109:     
                   6110:     
                   6111:     for(h=0; h<=nhstepm-1; h++)
                   6112:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  6113:        for(theta=1; theta <=npar; theta++)
                   6114:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  6115:     
1.218     brouard  6116:                
1.222     brouard  6117:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  6118:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  6119:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  6120:                
1.222     brouard  6121:     printf("%d|",(int)age);fflush(stdout);
                   6122:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   6123:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  6124:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  6125:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   6126:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   6127:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   6128:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   6129:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  6130:       }
                   6131:     }
1.320     brouard  6132:     /* if((int)age ==50){ */
                   6133:     /*   printf(" age=%d cij=%d nres=%d varhe[%d][%d]=%f ",(int)age, cij, nres, 1,2,varhe[1][2]); */
                   6134:     /* } */
1.126     brouard  6135:     /* Computing expectancies */
1.235     brouard  6136:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  6137:     for(i=1; i<=nlstate;i++)
                   6138:       for(j=1; j<=nlstate;j++)
1.222     brouard  6139:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   6140:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  6141:                                        
1.222     brouard  6142:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  6143:                                        
1.222     brouard  6144:        }
1.269     brouard  6145: 
                   6146:     /* Standard deviation of expectancies ij */                
1.126     brouard  6147:     fprintf(ficresstdeij,"%3.0f",age );
                   6148:     for(i=1; i<=nlstate;i++){
                   6149:       eip=0.;
                   6150:       vip=0.;
                   6151:       for(j=1; j<=nlstate;j++){
1.222     brouard  6152:        eip += eij[i][j][(int)age];
                   6153:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   6154:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   6155:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  6156:       }
                   6157:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   6158:     }
                   6159:     fprintf(ficresstdeij,"\n");
1.218     brouard  6160:                
1.269     brouard  6161:     /* Variance of expectancies ij */          
1.126     brouard  6162:     fprintf(ficrescveij,"%3.0f",age );
                   6163:     for(i=1; i<=nlstate;i++)
                   6164:       for(j=1; j<=nlstate;j++){
1.222     brouard  6165:        cptj= (j-1)*nlstate+i;
                   6166:        for(i2=1; i2<=nlstate;i2++)
                   6167:          for(j2=1; j2<=nlstate;j2++){
                   6168:            cptj2= (j2-1)*nlstate+i2;
                   6169:            if(cptj2 <= cptj)
                   6170:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   6171:          }
1.126     brouard  6172:       }
                   6173:     fprintf(ficrescveij,"\n");
1.218     brouard  6174:                
1.126     brouard  6175:   }
                   6176:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   6177:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   6178:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   6179:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   6180:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6181:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6182:   printf("\n");
                   6183:   fprintf(ficlog,"\n");
1.218     brouard  6184:        
1.126     brouard  6185:   free_vector(xm,1,npar);
                   6186:   free_vector(xp,1,npar);
                   6187:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   6188:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   6189:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   6190: }
1.218     brouard  6191:  
1.126     brouard  6192: /************ Variance ******************/
1.235     brouard  6193:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  6194:  {
1.279     brouard  6195:    /** Variance of health expectancies 
                   6196:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   6197:     * double **newm;
                   6198:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   6199:     */
1.218     brouard  6200:   
                   6201:    /* int movingaverage(); */
                   6202:    double **dnewm,**doldm;
                   6203:    double **dnewmp,**doldmp;
                   6204:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  6205:    int first=0;
1.218     brouard  6206:    int k;
                   6207:    double *xp;
1.279     brouard  6208:    double **gp, **gm;  /**< for var eij */
                   6209:    double ***gradg, ***trgradg; /**< for var eij */
                   6210:    double **gradgp, **trgradgp; /**< for var p point j */
                   6211:    double *gpp, *gmp; /**< for var p point j */
                   6212:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  6213:    double ***p3mat;
                   6214:    double age,agelim, hf;
                   6215:    /* double ***mobaverage; */
                   6216:    int theta;
                   6217:    char digit[4];
                   6218:    char digitp[25];
                   6219: 
                   6220:    char fileresprobmorprev[FILENAMELENGTH];
                   6221: 
                   6222:    if(popbased==1){
                   6223:      if(mobilav!=0)
                   6224:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   6225:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   6226:    }
                   6227:    else 
                   6228:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  6229: 
1.218     brouard  6230:    /* if (mobilav!=0) { */
                   6231:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6232:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   6233:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   6234:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   6235:    /*   } */
                   6236:    /* } */
                   6237: 
                   6238:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   6239:    sprintf(digit,"%-d",ij);
                   6240:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   6241:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   6242:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   6243:    strcat(fileresprobmorprev,fileresu);
                   6244:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   6245:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   6246:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   6247:    }
                   6248:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6249:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6250:    pstamp(ficresprobmorprev);
                   6251:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  6252:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   6253:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   6254:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   6255:    }
                   6256:    for(j=1;j<=cptcoveff;j++) 
                   6257:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   6258:    fprintf(ficresprobmorprev,"\n");
                   6259: 
1.218     brouard  6260:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   6261:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6262:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   6263:      for(i=1; i<=nlstate;i++)
                   6264:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   6265:    }  
                   6266:    fprintf(ficresprobmorprev,"\n");
                   6267:   
                   6268:    fprintf(ficgp,"\n# Routine varevsij");
                   6269:    fprintf(ficgp,"\nunset title \n");
                   6270:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   6271:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   6272:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  6273: 
1.218     brouard  6274:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6275:    pstamp(ficresvij);
                   6276:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   6277:    if(popbased==1)
                   6278:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   6279:    else
                   6280:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   6281:    fprintf(ficresvij,"# Age");
                   6282:    for(i=1; i<=nlstate;i++)
                   6283:      for(j=1; j<=nlstate;j++)
                   6284:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   6285:    fprintf(ficresvij,"\n");
                   6286: 
                   6287:    xp=vector(1,npar);
                   6288:    dnewm=matrix(1,nlstate,1,npar);
                   6289:    doldm=matrix(1,nlstate,1,nlstate);
                   6290:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   6291:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6292: 
                   6293:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   6294:    gpp=vector(nlstate+1,nlstate+ndeath);
                   6295:    gmp=vector(nlstate+1,nlstate+ndeath);
                   6296:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  6297:   
1.218     brouard  6298:    if(estepm < stepm){
                   6299:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   6300:    }
                   6301:    else  hstepm=estepm;   
                   6302:    /* For example we decided to compute the life expectancy with the smallest unit */
                   6303:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6304:       nhstepm is the number of hstepm from age to agelim 
                   6305:       nstepm is the number of stepm from age to agelim. 
                   6306:       Look at function hpijx to understand why because of memory size limitations, 
                   6307:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   6308:       survival function given by stepm (the optimization length). Unfortunately it
                   6309:       means that if the survival funtion is printed every two years of age and if
                   6310:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6311:       results. So we changed our mind and took the option of the best precision.
                   6312:    */
                   6313:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6314:    agelim = AGESUP;
                   6315:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6316:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6317:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6318:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6319:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   6320:      gp=matrix(0,nhstepm,1,nlstate);
                   6321:      gm=matrix(0,nhstepm,1,nlstate);
                   6322:                
                   6323:                
                   6324:      for(theta=1; theta <=npar; theta++){
                   6325:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   6326:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6327:        }
1.279     brouard  6328:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   6329:        * returns into prlim .
1.288     brouard  6330:        */
1.242     brouard  6331:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  6332: 
                   6333:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  6334:        if (popbased==1) {
                   6335:         if(mobilav ==0){
                   6336:           for(i=1; i<=nlstate;i++)
                   6337:             prlim[i][i]=probs[(int)age][i][ij];
                   6338:         }else{ /* mobilav */ 
                   6339:           for(i=1; i<=nlstate;i++)
                   6340:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6341:         }
                   6342:        }
1.295     brouard  6343:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}x\f$ at horizon h.
1.279     brouard  6344:        */                      
                   6345:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
1.292     brouard  6346:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}x\f$, which are the probability
1.279     brouard  6347:        * at horizon h in state j including mortality.
                   6348:        */
1.218     brouard  6349:        for(j=1; j<= nlstate; j++){
                   6350:         for(h=0; h<=nhstepm; h++){
                   6351:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6352:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6353:         }
                   6354:        }
1.279     brouard  6355:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6356:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6357:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6358:        */
                   6359:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6360:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6361:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6362:        }
                   6363:        
                   6364:        /* Again with minus shift */
1.218     brouard  6365:                        
                   6366:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6367:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6368: 
1.242     brouard  6369:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6370:                        
                   6371:        if (popbased==1) {
                   6372:         if(mobilav ==0){
                   6373:           for(i=1; i<=nlstate;i++)
                   6374:             prlim[i][i]=probs[(int)age][i][ij];
                   6375:         }else{ /* mobilav */ 
                   6376:           for(i=1; i<=nlstate;i++)
                   6377:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6378:         }
                   6379:        }
                   6380:                        
1.235     brouard  6381:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6382:                        
                   6383:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6384:         for(h=0; h<=nhstepm; h++){
                   6385:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6386:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6387:         }
                   6388:        }
                   6389:        /* This for computing probability of death (h=1 means
                   6390:          computed over hstepm matrices product = hstepm*stepm months) 
                   6391:          as a weighted average of prlim.
                   6392:        */
                   6393:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6394:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6395:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6396:        }    
1.279     brouard  6397:        /* end shifting computations */
                   6398: 
                   6399:        /**< Computing gradient matrix at horizon h 
                   6400:        */
1.218     brouard  6401:        for(j=1; j<= nlstate; j++) /* vareij */
                   6402:         for(h=0; h<=nhstepm; h++){
                   6403:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6404:         }
1.279     brouard  6405:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6406:        */
                   6407:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6408:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6409:        }
                   6410:                        
                   6411:      } /* End theta */
1.279     brouard  6412:      
                   6413:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6414:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6415:                
                   6416:      for(h=0; h<=nhstepm; h++) /* veij */
                   6417:        for(j=1; j<=nlstate;j++)
                   6418:         for(theta=1; theta <=npar; theta++)
                   6419:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6420:                
                   6421:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6422:        for(theta=1; theta <=npar; theta++)
                   6423:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6424:      /**< as well as its transposed matrix 
                   6425:       */               
1.218     brouard  6426:                
                   6427:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6428:      for(i=1;i<=nlstate;i++)
                   6429:        for(j=1;j<=nlstate;j++)
                   6430:         vareij[i][j][(int)age] =0.;
1.279     brouard  6431: 
                   6432:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6433:       * and k (nhstepm) formula 15 of article
                   6434:       * Lievre-Brouard-Heathcote
                   6435:       */
                   6436:      
1.218     brouard  6437:      for(h=0;h<=nhstepm;h++){
                   6438:        for(k=0;k<=nhstepm;k++){
                   6439:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6440:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6441:         for(i=1;i<=nlstate;i++)
                   6442:           for(j=1;j<=nlstate;j++)
                   6443:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6444:        }
                   6445:      }
                   6446:                
1.279     brouard  6447:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6448:       * p.j overall mortality formula 49 but computed directly because
                   6449:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6450:       * wix is independent of theta.
                   6451:       */
1.218     brouard  6452:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6453:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6454:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6455:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6456:         varppt[j][i]=doldmp[j][i];
                   6457:      /* end ppptj */
                   6458:      /*  x centered again */
                   6459:                
1.242     brouard  6460:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6461:                
                   6462:      if (popbased==1) {
                   6463:        if(mobilav ==0){
                   6464:         for(i=1; i<=nlstate;i++)
                   6465:           prlim[i][i]=probs[(int)age][i][ij];
                   6466:        }else{ /* mobilav */ 
                   6467:         for(i=1; i<=nlstate;i++)
                   6468:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6469:        }
                   6470:      }
                   6471:                
                   6472:      /* This for computing probability of death (h=1 means
                   6473:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6474:        as a weighted average of prlim.
                   6475:      */
1.235     brouard  6476:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6477:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6478:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6479:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6480:      }    
                   6481:      /* end probability of death */
                   6482:                
                   6483:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6484:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6485:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6486:        for(i=1; i<=nlstate;i++){
                   6487:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6488:        }
                   6489:      } 
                   6490:      fprintf(ficresprobmorprev,"\n");
                   6491:                
                   6492:      fprintf(ficresvij,"%.0f ",age );
                   6493:      for(i=1; i<=nlstate;i++)
                   6494:        for(j=1; j<=nlstate;j++){
                   6495:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6496:        }
                   6497:      fprintf(ficresvij,"\n");
                   6498:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6499:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6500:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6501:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6502:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6503:    } /* End age */
                   6504:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6505:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6506:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6507:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6508:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6509:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6510:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6511:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6512:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6513:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6514:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6515:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6516:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6517:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6518:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6519:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6520:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6521:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6522:     */
1.218     brouard  6523:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6524:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6525: 
1.218     brouard  6526:    free_vector(xp,1,npar);
                   6527:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6528:    free_matrix(dnewm,1,nlstate,1,npar);
                   6529:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6530:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6531:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6532:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6533:    fclose(ficresprobmorprev);
                   6534:    fflush(ficgp);
                   6535:    fflush(fichtm); 
                   6536:  }  /* end varevsij */
1.126     brouard  6537: 
                   6538: /************ Variance of prevlim ******************/
1.269     brouard  6539:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6540: {
1.205     brouard  6541:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6542:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6543: 
1.268     brouard  6544:   double **dnewmpar,**doldm;
1.126     brouard  6545:   int i, j, nhstepm, hstepm;
                   6546:   double *xp;
                   6547:   double *gp, *gm;
                   6548:   double **gradg, **trgradg;
1.208     brouard  6549:   double **mgm, **mgp;
1.126     brouard  6550:   double age,agelim;
                   6551:   int theta;
                   6552:   
                   6553:   pstamp(ficresvpl);
1.288     brouard  6554:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6555:   fprintf(ficresvpl,"# Age ");
                   6556:   if(nresult >=1)
                   6557:     fprintf(ficresvpl," Result# ");
1.126     brouard  6558:   for(i=1; i<=nlstate;i++)
                   6559:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6560:   fprintf(ficresvpl,"\n");
                   6561: 
                   6562:   xp=vector(1,npar);
1.268     brouard  6563:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6564:   doldm=matrix(1,nlstate,1,nlstate);
                   6565:   
                   6566:   hstepm=1*YEARM; /* Every year of age */
                   6567:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6568:   agelim = AGESUP;
                   6569:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6570:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6571:     if (stepm >= YEARM) hstepm=1;
                   6572:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6573:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6574:     mgp=matrix(1,npar,1,nlstate);
                   6575:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6576:     gp=vector(1,nlstate);
                   6577:     gm=vector(1,nlstate);
                   6578: 
                   6579:     for(theta=1; theta <=npar; theta++){
                   6580:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6581:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6582:       }
1.288     brouard  6583:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6584:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6585:       /* else */
                   6586:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6587:       for(i=1;i<=nlstate;i++){
1.126     brouard  6588:        gp[i] = prlim[i][i];
1.208     brouard  6589:        mgp[theta][i] = prlim[i][i];
                   6590:       }
1.126     brouard  6591:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6592:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6593:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6594:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6595:       /* else */
                   6596:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6597:       for(i=1;i<=nlstate;i++){
1.126     brouard  6598:        gm[i] = prlim[i][i];
1.208     brouard  6599:        mgm[theta][i] = prlim[i][i];
                   6600:       }
1.126     brouard  6601:       for(i=1;i<=nlstate;i++)
                   6602:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6603:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6604:     } /* End theta */
                   6605: 
                   6606:     trgradg =matrix(1,nlstate,1,npar);
                   6607: 
                   6608:     for(j=1; j<=nlstate;j++)
                   6609:       for(theta=1; theta <=npar; theta++)
                   6610:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6611:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6612:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6613:     /*   for(j=1; j<=nlstate;j++){ */
                   6614:     /*         printf(" %d ",j); */
                   6615:     /*         for(theta=1; theta <=npar; theta++) */
                   6616:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6617:     /*         printf("\n "); */
                   6618:     /*   } */
                   6619:     /* } */
                   6620:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6621:     /*   printf("\n gradg %d ",(int)age); */
                   6622:     /*   for(j=1; j<=nlstate;j++){ */
                   6623:     /*         printf("%d ",j); */
                   6624:     /*         for(theta=1; theta <=npar; theta++) */
                   6625:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6626:     /*         printf("\n "); */
                   6627:     /*   } */
                   6628:     /* } */
1.126     brouard  6629: 
                   6630:     for(i=1;i<=nlstate;i++)
                   6631:       varpl[i][(int)age] =0.;
1.209     brouard  6632:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6633:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6634:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6635:     }else{
1.268     brouard  6636:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6637:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6638:     }
1.126     brouard  6639:     for(i=1;i<=nlstate;i++)
                   6640:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6641: 
                   6642:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6643:     if(nresult >=1)
                   6644:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6645:     for(i=1; i<=nlstate;i++){
1.126     brouard  6646:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6647:       /* for(j=1;j<=nlstate;j++) */
                   6648:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6649:     }
1.126     brouard  6650:     fprintf(ficresvpl,"\n");
                   6651:     free_vector(gp,1,nlstate);
                   6652:     free_vector(gm,1,nlstate);
1.208     brouard  6653:     free_matrix(mgm,1,npar,1,nlstate);
                   6654:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6655:     free_matrix(gradg,1,npar,1,nlstate);
                   6656:     free_matrix(trgradg,1,nlstate,1,npar);
                   6657:   } /* End age */
                   6658: 
                   6659:   free_vector(xp,1,npar);
                   6660:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6661:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6662: 
                   6663: }
                   6664: 
                   6665: 
                   6666: /************ Variance of backprevalence limit ******************/
1.269     brouard  6667:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6668: {
                   6669:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6670:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6671: 
                   6672:   double **dnewmpar,**doldm;
                   6673:   int i, j, nhstepm, hstepm;
                   6674:   double *xp;
                   6675:   double *gp, *gm;
                   6676:   double **gradg, **trgradg;
                   6677:   double **mgm, **mgp;
                   6678:   double age,agelim;
                   6679:   int theta;
                   6680:   
                   6681:   pstamp(ficresvbl);
                   6682:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6683:   fprintf(ficresvbl,"# Age ");
                   6684:   if(nresult >=1)
                   6685:     fprintf(ficresvbl," Result# ");
                   6686:   for(i=1; i<=nlstate;i++)
                   6687:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6688:   fprintf(ficresvbl,"\n");
                   6689: 
                   6690:   xp=vector(1,npar);
                   6691:   dnewmpar=matrix(1,nlstate,1,npar);
                   6692:   doldm=matrix(1,nlstate,1,nlstate);
                   6693:   
                   6694:   hstepm=1*YEARM; /* Every year of age */
                   6695:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6696:   agelim = AGEINF;
                   6697:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6698:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6699:     if (stepm >= YEARM) hstepm=1;
                   6700:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6701:     gradg=matrix(1,npar,1,nlstate);
                   6702:     mgp=matrix(1,npar,1,nlstate);
                   6703:     mgm=matrix(1,npar,1,nlstate);
                   6704:     gp=vector(1,nlstate);
                   6705:     gm=vector(1,nlstate);
                   6706: 
                   6707:     for(theta=1; theta <=npar; theta++){
                   6708:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6709:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6710:       }
                   6711:       if(mobilavproj > 0 )
                   6712:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6713:       else
                   6714:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6715:       for(i=1;i<=nlstate;i++){
                   6716:        gp[i] = bprlim[i][i];
                   6717:        mgp[theta][i] = bprlim[i][i];
                   6718:       }
                   6719:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6720:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6721:        if(mobilavproj > 0 )
                   6722:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6723:        else
                   6724:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6725:       for(i=1;i<=nlstate;i++){
                   6726:        gm[i] = bprlim[i][i];
                   6727:        mgm[theta][i] = bprlim[i][i];
                   6728:       }
                   6729:       for(i=1;i<=nlstate;i++)
                   6730:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6731:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6732:     } /* End theta */
                   6733: 
                   6734:     trgradg =matrix(1,nlstate,1,npar);
                   6735: 
                   6736:     for(j=1; j<=nlstate;j++)
                   6737:       for(theta=1; theta <=npar; theta++)
                   6738:        trgradg[j][theta]=gradg[theta][j];
                   6739:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6740:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6741:     /*   for(j=1; j<=nlstate;j++){ */
                   6742:     /*         printf(" %d ",j); */
                   6743:     /*         for(theta=1; theta <=npar; theta++) */
                   6744:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6745:     /*         printf("\n "); */
                   6746:     /*   } */
                   6747:     /* } */
                   6748:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6749:     /*   printf("\n gradg %d ",(int)age); */
                   6750:     /*   for(j=1; j<=nlstate;j++){ */
                   6751:     /*         printf("%d ",j); */
                   6752:     /*         for(theta=1; theta <=npar; theta++) */
                   6753:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6754:     /*         printf("\n "); */
                   6755:     /*   } */
                   6756:     /* } */
                   6757: 
                   6758:     for(i=1;i<=nlstate;i++)
                   6759:       varbpl[i][(int)age] =0.;
                   6760:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6761:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6762:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6763:     }else{
                   6764:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6765:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6766:     }
                   6767:     for(i=1;i<=nlstate;i++)
                   6768:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6769: 
                   6770:     fprintf(ficresvbl,"%.0f ",age );
                   6771:     if(nresult >=1)
                   6772:       fprintf(ficresvbl,"%d ",nres );
                   6773:     for(i=1; i<=nlstate;i++)
                   6774:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6775:     fprintf(ficresvbl,"\n");
                   6776:     free_vector(gp,1,nlstate);
                   6777:     free_vector(gm,1,nlstate);
                   6778:     free_matrix(mgm,1,npar,1,nlstate);
                   6779:     free_matrix(mgp,1,npar,1,nlstate);
                   6780:     free_matrix(gradg,1,npar,1,nlstate);
                   6781:     free_matrix(trgradg,1,nlstate,1,npar);
                   6782:   } /* End age */
                   6783: 
                   6784:   free_vector(xp,1,npar);
                   6785:   free_matrix(doldm,1,nlstate,1,npar);
                   6786:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6787: 
                   6788: }
                   6789: 
                   6790: /************ Variance of one-step probabilities  ******************/
                   6791: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6792:  {
                   6793:    int i, j=0,  k1, l1, tj;
                   6794:    int k2, l2, j1,  z1;
                   6795:    int k=0, l;
                   6796:    int first=1, first1, first2;
                   6797:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6798:    double **dnewm,**doldm;
                   6799:    double *xp;
                   6800:    double *gp, *gm;
                   6801:    double **gradg, **trgradg;
                   6802:    double **mu;
                   6803:    double age, cov[NCOVMAX+1];
                   6804:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6805:    int theta;
                   6806:    char fileresprob[FILENAMELENGTH];
                   6807:    char fileresprobcov[FILENAMELENGTH];
                   6808:    char fileresprobcor[FILENAMELENGTH];
                   6809:    double ***varpij;
                   6810: 
                   6811:    strcpy(fileresprob,"PROB_"); 
                   6812:    strcat(fileresprob,fileres);
                   6813:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6814:      printf("Problem with resultfile: %s\n", fileresprob);
                   6815:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6816:    }
                   6817:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6818:    strcat(fileresprobcov,fileresu);
                   6819:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6820:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6821:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6822:    }
                   6823:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6824:    strcat(fileresprobcor,fileresu);
                   6825:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6826:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6827:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6828:    }
                   6829:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6830:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6831:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6832:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6833:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6834:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6835:    pstamp(ficresprob);
                   6836:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6837:    fprintf(ficresprob,"# Age");
                   6838:    pstamp(ficresprobcov);
                   6839:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6840:    fprintf(ficresprobcov,"# Age");
                   6841:    pstamp(ficresprobcor);
                   6842:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6843:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6844: 
                   6845: 
1.222     brouard  6846:    for(i=1; i<=nlstate;i++)
                   6847:      for(j=1; j<=(nlstate+ndeath);j++){
                   6848:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6849:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6850:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6851:      }  
                   6852:    /* fprintf(ficresprob,"\n");
                   6853:       fprintf(ficresprobcov,"\n");
                   6854:       fprintf(ficresprobcor,"\n");
                   6855:    */
                   6856:    xp=vector(1,npar);
                   6857:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6858:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6859:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6860:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6861:    first=1;
                   6862:    fprintf(ficgp,"\n# Routine varprob");
                   6863:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6864:    fprintf(fichtm,"\n");
                   6865: 
1.288     brouard  6866:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6867:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6868:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6869: and drawn. It helps understanding how is the covariance between two incidences.\
                   6870:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6871:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6872: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6873: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6874: standard deviations wide on each axis. <br>\
                   6875:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6876:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6877: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6878: 
1.222     brouard  6879:    cov[1]=1;
                   6880:    /* tj=cptcoveff; */
1.225     brouard  6881:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6882:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6883:    j1=0;
1.224     brouard  6884:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6885:      if  (cptcovn>0) {
                   6886:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6887:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6888:        fprintf(ficresprob, "**********\n#\n");
                   6889:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6890:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6891:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6892:                        
1.222     brouard  6893:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6894:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6895:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6896:                        
                   6897:                        
1.222     brouard  6898:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.319     brouard  6899:        /* for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); */
                   6900:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtmcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6901:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6902:                        
1.222     brouard  6903:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6904:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6905:        fprintf(ficresprobcor, "**********\n#");    
                   6906:        if(invalidvarcomb[j1]){
                   6907:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6908:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6909:         continue;
                   6910:        }
                   6911:      }
                   6912:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6913:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6914:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6915:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6916:      for (age=bage; age<=fage; age ++){ 
                   6917:        cov[2]=age;
                   6918:        if(nagesqr==1)
                   6919:         cov[3]= age*age;
                   6920:        for (k=1; k<=cptcovn;k++) {
                   6921:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6922:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6923:                                                                    * 1  1 1 1 1
                   6924:                                                                    * 2  2 1 1 1
                   6925:                                                                    * 3  1 2 1 1
                   6926:                                                                    */
                   6927:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6928:        }
1.319     brouard  6929:        /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   6930:        /* ) p nbcode[Tvar[Tage[k]]][(1 & (ij-1) >> (k-1))+1] */
                   6931:        /*for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6932:        for (k=1; k<=cptcovage;k++)
                   6933:         cov[2+Tage[k]+nagesqr]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.222     brouard  6934:        for (k=1; k<=cptcovprod;k++)
                   6935:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6936:                        
                   6937:                        
1.222     brouard  6938:        for(theta=1; theta <=npar; theta++){
                   6939:         for(i=1; i<=npar; i++)
                   6940:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6941:                                
1.222     brouard  6942:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6943:                                
1.222     brouard  6944:         k=0;
                   6945:         for(i=1; i<= (nlstate); i++){
                   6946:           for(j=1; j<=(nlstate+ndeath);j++){
                   6947:             k=k+1;
                   6948:             gp[k]=pmmij[i][j];
                   6949:           }
                   6950:         }
1.220     brouard  6951:                                
1.222     brouard  6952:         for(i=1; i<=npar; i++)
                   6953:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6954:                                
1.222     brouard  6955:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6956:         k=0;
                   6957:         for(i=1; i<=(nlstate); i++){
                   6958:           for(j=1; j<=(nlstate+ndeath);j++){
                   6959:             k=k+1;
                   6960:             gm[k]=pmmij[i][j];
                   6961:           }
                   6962:         }
1.220     brouard  6963:                                
1.222     brouard  6964:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6965:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6966:        }
1.126     brouard  6967: 
1.222     brouard  6968:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6969:         for(theta=1; theta <=npar; theta++)
                   6970:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6971:                        
1.222     brouard  6972:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6973:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6974:                        
1.222     brouard  6975:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6976:                        
1.222     brouard  6977:        k=0;
                   6978:        for(i=1; i<=(nlstate); i++){
                   6979:         for(j=1; j<=(nlstate+ndeath);j++){
                   6980:           k=k+1;
                   6981:           mu[k][(int) age]=pmmij[i][j];
                   6982:         }
                   6983:        }
                   6984:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6985:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6986:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6987:                        
1.222     brouard  6988:        /*printf("\n%d ",(int)age);
                   6989:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6990:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6991:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6992:         }*/
1.220     brouard  6993:                        
1.222     brouard  6994:        fprintf(ficresprob,"\n%d ",(int)age);
                   6995:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6996:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6997:                        
1.222     brouard  6998:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6999:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   7000:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   7001:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   7002:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   7003:        }
                   7004:        i=0;
                   7005:        for (k=1; k<=(nlstate);k++){
                   7006:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   7007:           i++;
                   7008:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   7009:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   7010:           for (j=1; j<=i;j++){
                   7011:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   7012:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   7013:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   7014:           }
                   7015:         }
                   7016:        }/* end of loop for state */
                   7017:      } /* end of loop for age */
                   7018:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   7019:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   7020:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   7021:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   7022:     
                   7023:      /* Confidence intervalle of pij  */
                   7024:      /*
                   7025:        fprintf(ficgp,"\nunset parametric;unset label");
                   7026:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   7027:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   7028:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   7029:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   7030:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   7031:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   7032:      */
                   7033:                
                   7034:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   7035:      first1=1;first2=2;
                   7036:      for (k2=1; k2<=(nlstate);k2++){
                   7037:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   7038:         if(l2==k2) continue;
                   7039:         j=(k2-1)*(nlstate+ndeath)+l2;
                   7040:         for (k1=1; k1<=(nlstate);k1++){
                   7041:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   7042:             if(l1==k1) continue;
                   7043:             i=(k1-1)*(nlstate+ndeath)+l1;
                   7044:             if(i<=j) continue;
                   7045:             for (age=bage; age<=fage; age ++){ 
                   7046:               if ((int)age %5==0){
                   7047:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   7048:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   7049:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   7050:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   7051:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   7052:                 c12=cv12/sqrt(v1*v2);
                   7053:                 /* Computing eigen value of matrix of covariance */
                   7054:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   7055:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   7056:                 if ((lc2 <0) || (lc1 <0) ){
                   7057:                   if(first2==1){
                   7058:                     first1=0;
                   7059:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   7060:                   }
                   7061:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   7062:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   7063:                   /* lc2=fabs(lc2); */
                   7064:                 }
1.220     brouard  7065:                                                                
1.222     brouard  7066:                 /* Eigen vectors */
1.280     brouard  7067:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   7068:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   7069:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   7070:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   7071:                 }else
                   7072:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  7073:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   7074:                 v21=(lc1-v1)/cv12*v11;
                   7075:                 v12=-v21;
                   7076:                 v22=v11;
                   7077:                 tnalp=v21/v11;
                   7078:                 if(first1==1){
                   7079:                   first1=0;
                   7080:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   7081:                 }
                   7082:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   7083:                 /*printf(fignu*/
                   7084:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   7085:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   7086:                 if(first==1){
                   7087:                   first=0;
                   7088:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   7089:                   fprintf(ficgp,"\nset parametric;unset label");
                   7090:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   7091:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  7092:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  7093:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  7094: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  7095:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   7096:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7097:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7098:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   7099:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7100:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   7101:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   7102:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  7103:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   7104:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  7105:                 }else{
                   7106:                   first=0;
                   7107:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   7108:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   7109:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   7110:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  7111:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   7112:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  7113:                 }/* if first */
                   7114:               } /* age mod 5 */
                   7115:             } /* end loop age */
                   7116:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7117:             first=1;
                   7118:           } /*l12 */
                   7119:         } /* k12 */
                   7120:        } /*l1 */
                   7121:      }/* k1 */
                   7122:    }  /* loop on combination of covariates j1 */
                   7123:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   7124:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   7125:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   7126:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   7127:    free_vector(xp,1,npar);
                   7128:    fclose(ficresprob);
                   7129:    fclose(ficresprobcov);
                   7130:    fclose(ficresprobcor);
                   7131:    fflush(ficgp);
                   7132:    fflush(fichtmcov);
                   7133:  }
1.126     brouard  7134: 
                   7135: 
                   7136: /******************* Printing html file ***********/
1.201     brouard  7137: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  7138:                  int lastpass, int stepm, int weightopt, char model[],\
                   7139:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.296     brouard  7140:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int prevbcast, int estepm , \
                   7141:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateprojd, double dateback1, \
                   7142:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateprojf, double dateback2){
1.237     brouard  7143:   int jj1, k1, i1, cpt, k4, nres;
1.319     brouard  7144:   /* In fact some results are already printed in fichtm which is open */
1.126     brouard  7145:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   7146:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   7147: </ul>");
1.319     brouard  7148: /*    fprintf(fichtm,"<ul><li> model=1+age+%s\n \ */
                   7149: /* </ul>", model); */
1.214     brouard  7150:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   7151:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   7152:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   7153:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  7154:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   7155:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  7156:    fprintf(fichtm,"\
                   7157:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  7158:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  7159:    fprintf(fichtm,"\
1.217     brouard  7160:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   7161:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   7162:    fprintf(fichtm,"\
1.288     brouard  7163:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  7164:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  7165:    fprintf(fichtm,"\
1.288     brouard  7166:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  7167:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   7168:    fprintf(fichtm,"\
1.211     brouard  7169:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  7170:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  7171:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  7172:    if(prevfcast==1){
                   7173:      fprintf(fichtm,"\
                   7174:  - Prevalence projections by age and states:                           \
1.201     brouard  7175:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  7176:    }
1.126     brouard  7177: 
                   7178: 
1.225     brouard  7179:    m=pow(2,cptcoveff);
1.222     brouard  7180:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7181: 
1.317     brouard  7182:    fprintf(fichtm," \n<ul><li><b>Graphs (first order)</b></li><p>");
1.264     brouard  7183: 
                   7184:    jj1=0;
                   7185: 
                   7186:    fprintf(fichtm," \n<ul>");
                   7187:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7188:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   7189:      if(m != 1 && TKresult[nres]!= k1)
                   7190:        continue;
                   7191:      jj1++;
                   7192:      if (cptcovn > 0) {
                   7193:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   7194:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7195:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7196:        }
                   7197:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7198:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7199:        }
                   7200:        fprintf(fichtm,"\">");
                   7201:        
                   7202:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   7203:        fprintf(fichtm,"************ Results for covariates");
                   7204:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7205:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7206:        }
                   7207:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7208:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7209:        }
                   7210:        if(invalidvarcomb[k1]){
                   7211:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   7212:         continue;
                   7213:        }
                   7214:        fprintf(fichtm,"</a></li>");
                   7215:      } /* cptcovn >0 */
                   7216:    }
1.317     brouard  7217:    fprintf(fichtm," \n</ul>");
1.264     brouard  7218: 
1.222     brouard  7219:    jj1=0;
1.237     brouard  7220: 
                   7221:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  7222:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  7223:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7224:        continue;
1.220     brouard  7225: 
1.222     brouard  7226:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7227:      jj1++;
                   7228:      if (cptcovn > 0) {
1.264     brouard  7229:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   7230:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7231:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7232:        }
                   7233:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7234:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7235:        }
                   7236:        fprintf(fichtm,"\"</a>");
                   7237:  
1.222     brouard  7238:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7239:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  7240:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7241:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   7242:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7243:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  7244:        }
1.237     brouard  7245:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7246:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7247:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   7248:       }
                   7249:        
1.230     brouard  7250:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.321     brouard  7251:        fprintf(fichtm," (model=%s) ************\n<hr size=\"2\" color=\"#EC5E5E\">",model);
1.222     brouard  7252:        if(invalidvarcomb[k1]){
                   7253:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   7254:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   7255:         continue;
                   7256:        }
                   7257:      }
                   7258:      /* aij, bij */
1.259     brouard  7259:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  7260: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  7261:      /* Pij */
1.241     brouard  7262:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   7263: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  7264:      /* Quasi-incidences */
                   7265:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  7266:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  7267:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  7268: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   7269: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  7270:      /* Survival functions (period) in state j */
                   7271:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7272:        fprintf(fichtm,"<br>\n- Survival functions in state %d. And probability to be observed in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7273: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  7274:      }
                   7275:      /* State specific survival functions (period) */
                   7276:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7277:        fprintf(fichtm,"<br>\n- Survival functions in state %d and in any other live state (total).\
                   7278:  And probability to be observed in various states (up to %d) being in state %d at different ages.      \
1.283     brouard  7279:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  7280:      }
1.288     brouard  7281:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  7282:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7283:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7284: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  7285:      }
1.296     brouard  7286:      if(prevbcast==1){
1.288     brouard  7287:        /* Backward prevalence in each health state */
1.222     brouard  7288:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7289:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7290: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  7291:        }
1.217     brouard  7292:      }
1.222     brouard  7293:      if(prevfcast==1){
1.288     brouard  7294:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  7295:        for(cpt=1; cpt<=nlstate;cpt++){
1.314     brouard  7296:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>", dateprev1, dateprev2, mobilavproj, dateprojd, dateprojf, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
                   7297:         fprintf(fichtm," (data from text file  <a href=\"%s.txt\">%s.txt</a>)\n<br>",subdirf2(optionfilefiname,"F_"),subdirf2(optionfilefiname,"F_"));
                   7298:         fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">",
                   7299:                 subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  7300:        }
                   7301:      }
1.296     brouard  7302:      if(prevbcast==1){
1.268     brouard  7303:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   7304:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  7305:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   7306:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   7307:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
1.314     brouard  7308: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7309:         fprintf(fichtm," (data from text file  <a href=\"%s.txt\">%s.txt</a>)\n<br>",subdirf2(optionfilefiname,"FB_"),subdirf2(optionfilefiname,"FB_"));
                   7310:         fprintf(fichtm," <img src=\"%s_%d-%d-%d.svg\">", subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  7311:        }
                   7312:      }
1.220     brouard  7313:         
1.222     brouard  7314:      for(cpt=1; cpt<=nlstate;cpt++) {
1.314     brouard  7315:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
                   7316:        fprintf(fichtm," (data from text file  <a href=\"%s.txt\"> %s.txt</a>)\n<br>",subdirf2(optionfilefiname,"E_"),subdirf2(optionfilefiname,"E_"));
                   7317:        fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">", subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres );
1.222     brouard  7318:      }
                   7319:      /* } /\* end i1 *\/ */
                   7320:    }/* End k1 */
                   7321:    fprintf(fichtm,"</ul>");
1.126     brouard  7322: 
1.222     brouard  7323:    fprintf(fichtm,"\
1.126     brouard  7324: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  7325:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  7326:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  7327: But because parameters are usually highly correlated (a higher incidence of disability \
                   7328: and a higher incidence of recovery can give very close observed transition) it might \
                   7329: be very useful to look not only at linear confidence intervals estimated from the \
                   7330: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   7331: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   7332: covariance matrix of the one-step probabilities. \
                   7333: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  7334: 
1.222     brouard  7335:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   7336:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   7337:    fprintf(fichtm,"\
1.126     brouard  7338:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7339:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  7340: 
1.222     brouard  7341:    fprintf(fichtm,"\
1.126     brouard  7342:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7343:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   7344:    fprintf(fichtm,"\
1.126     brouard  7345:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7346:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7347:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7348:    fprintf(fichtm,"\
1.126     brouard  7349:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7350:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7351:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7352:    fprintf(fichtm,"\
1.288     brouard  7353:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7354:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7355:    fprintf(fichtm,"\
1.128     brouard  7356:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7357:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7358:    fprintf(fichtm,"\
1.288     brouard  7359:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7360:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7361: 
                   7362: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7363: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7364: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7365: /*     <br>",fileres,fileres,fileres,fileres); */
                   7366: /*  else  */
                   7367: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7368:    fflush(fichtm);
1.126     brouard  7369: 
1.225     brouard  7370:    m=pow(2,cptcoveff);
1.222     brouard  7371:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7372: 
1.317     brouard  7373:    fprintf(fichtm," <ul><li><b>Graphs (second order)</b></li><p>");
                   7374: 
                   7375:   jj1=0;
                   7376: 
                   7377:    fprintf(fichtm," \n<ul>");
                   7378:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7379:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   7380:      if(m != 1 && TKresult[nres]!= k1)
                   7381:        continue;
                   7382:      jj1++;
                   7383:      if (cptcovn > 0) {
                   7384:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescovsecond");
                   7385:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7386:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7387:        }
                   7388:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7389:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7390:        }
                   7391:        fprintf(fichtm,"\">");
                   7392:        
                   7393:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   7394:        fprintf(fichtm,"************ Results for covariates");
                   7395:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7396:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7397:        }
                   7398:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7399:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7400:        }
                   7401:        if(invalidvarcomb[k1]){
                   7402:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   7403:         continue;
                   7404:        }
                   7405:        fprintf(fichtm,"</a></li>");
                   7406:      } /* cptcovn >0 */
                   7407:    }
                   7408:    fprintf(fichtm," \n</ul>");
                   7409: 
1.222     brouard  7410:    jj1=0;
1.237     brouard  7411: 
1.241     brouard  7412:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7413:    for(k1=1; k1<=m;k1++){
1.253     brouard  7414:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7415:        continue;
1.222     brouard  7416:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7417:      jj1++;
1.126     brouard  7418:      if (cptcovn > 0) {
1.317     brouard  7419:        fprintf(fichtm,"\n<p><a name=\"rescovsecond");
                   7420:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7421:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7422:        }
                   7423:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7424:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7425:        }
                   7426:        fprintf(fichtm,"\"</a>");
                   7427:        
1.126     brouard  7428:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.317     brouard  7429:        for (cpt=1; cpt<=cptcoveff;cpt++){  /**< cptcoveff number of variables */
1.237     brouard  7430:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
1.317     brouard  7431:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
1.237     brouard  7432:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
1.317     brouard  7433:        }
1.237     brouard  7434:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7435:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7436:       }
                   7437: 
1.321     brouard  7438:        fprintf(fichtm," (model=%s) ************\n<hr size=\"2\" color=\"#EC5E5E\">",model);
1.220     brouard  7439: 
1.222     brouard  7440:        if(invalidvarcomb[k1]){
                   7441:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7442:         continue;
                   7443:        }
1.126     brouard  7444:      }
                   7445:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7446:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.314     brouard  7447: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7448:        fprintf(fichtm," (data from text file  <a href=\"%s\">%s</a>)\n <br>",subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
                   7449:        fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">",subdirf2(optionfilefiname,"V_"), cpt,k1,nres);
1.126     brouard  7450:      }
                   7451:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.314     brouard  7452: health expectancies in each live states (1 to %d). If popbased=1 the smooth (due to the model) \
1.128     brouard  7453: true period expectancies (those weighted with period prevalences are also\
                   7454:  drawn in addition to the population based expectancies computed using\
1.314     brouard  7455:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>",nlstate, subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
                   7456:      fprintf(fichtm," (data from text file <a href=\"%s.txt\">%s.txt</a>) \n<br>",subdirf2(optionfilefiname,"T_"),subdirf2(optionfilefiname,"T_"));
                   7457:      fprintf(fichtm,"<img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7458:      /* } /\* end i1 *\/ */
                   7459:    }/* End k1 */
1.241     brouard  7460:   }/* End nres */
1.222     brouard  7461:    fprintf(fichtm,"</ul>");
                   7462:    fflush(fichtm);
1.126     brouard  7463: }
                   7464: 
                   7465: /******************* Gnuplot file **************/
1.296     brouard  7466: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int prevbcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7467: 
                   7468:   char dirfileres[132],optfileres[132];
1.264     brouard  7469:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7470:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7471:   int lv=0, vlv=0, kl=0;
1.130     brouard  7472:   int ng=0;
1.201     brouard  7473:   int vpopbased;
1.223     brouard  7474:   int ioffset; /* variable offset for columns */
1.270     brouard  7475:   int iyearc=1; /* variable column for year of projection  */
                   7476:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7477:   int nres=0; /* Index of resultline */
1.266     brouard  7478:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7479: 
1.126     brouard  7480: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7481: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7482: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7483: /*   } */
                   7484: 
                   7485:   /*#ifdef windows */
                   7486:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7487:   /*#endif */
1.225     brouard  7488:   m=pow(2,cptcoveff);
1.126     brouard  7489: 
1.274     brouard  7490:   /* diagram of the model */
                   7491:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7492:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7493:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7494:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7495: 
                   7496:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7497:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7498:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7499:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7500:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7501:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7502:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7503: 
1.202     brouard  7504:   /* Contribution to likelihood */
                   7505:   /* Plot the probability implied in the likelihood */
1.223     brouard  7506:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7507:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7508:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7509:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7510: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7511:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7512: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7513:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7514:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7515:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7516:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7517:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7518:   for (i=1; i<= nlstate ; i ++) {
                   7519:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7520:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7521:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7522:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7523:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7524:     }
                   7525:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7526:   }
                   7527:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7528:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7529:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7530:   fprintf(ficgp,"\nset out;unset log\n");
                   7531:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7532: 
1.126     brouard  7533:   strcpy(dirfileres,optionfilefiname);
                   7534:   strcpy(optfileres,"vpl");
1.223     brouard  7535:   /* 1eme*/
1.238     brouard  7536:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7537:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7538:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7539:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7540:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7541:          continue;
                   7542:        /* We are interested in selected combination by the resultline */
1.246     brouard  7543:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7544:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7545:        strcpy(gplotlabel,"(");
1.238     brouard  7546:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7547:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7548:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7549:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7550:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7551:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7552:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7553:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7554:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7555:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7556:        }
                   7557:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7558:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7559:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7560:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7561:        }
                   7562:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7563:        /* printf("\n#\n"); */
1.238     brouard  7564:        fprintf(ficgp,"\n#\n");
                   7565:        if(invalidvarcomb[k1]){
1.260     brouard  7566:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7567:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7568:          continue;
                   7569:        }
1.235     brouard  7570:       
1.241     brouard  7571:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7572:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7573:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
1.321     brouard  7574:        fprintf(ficgp,"set title \"Alive state %d %s model=%s\" font \"Helvetica,12\"\n",cpt,gplotlabel,model);
1.260     brouard  7575:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7576:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7577:       /* k1-1 error should be nres-1*/
1.238     brouard  7578:        for (i=1; i<= nlstate ; i ++) {
                   7579:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7580:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7581:        }
1.288     brouard  7582:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7583:        for (i=1; i<= nlstate ; i ++) {
                   7584:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7585:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7586:        } 
1.260     brouard  7587:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7588:        for (i=1; i<= nlstate ; i ++) {
                   7589:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7590:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7591:        }  
1.265     brouard  7592:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7593:        
                   7594:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7595:         if(cptcoveff ==0){
1.271     brouard  7596:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7597:        }else{
                   7598:          kl=0;
                   7599:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7600:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7601:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7602:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7603:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7604:            vlv= nbcode[Tvaraff[k]][lv];
                   7605:            kl++;
                   7606:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7607:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7608:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7609:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7610:            if(k==cptcoveff){
                   7611:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7612:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7613:            }else{
                   7614:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7615:              kl++;
                   7616:            }
                   7617:          } /* end covariate */
                   7618:        } /* end if no covariate */
                   7619: 
1.296     brouard  7620:        if(prevbcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
1.238     brouard  7621:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7622:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7623:          if(cptcoveff ==0){
1.245     brouard  7624:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7625:          }else{
                   7626:            kl=0;
                   7627:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7628:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7629:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7630:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7631:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7632:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7633:              kl++;
1.238     brouard  7634:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7635:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7636:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7637:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7638:              if(k==cptcoveff){
1.245     brouard  7639:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7640:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7641:              }else{
                   7642:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7643:                kl++;
                   7644:              }
                   7645:            } /* end covariate */
                   7646:          } /* end if no covariate */
1.296     brouard  7647:          if(prevbcast == 1){
1.268     brouard  7648:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7649:            /* k1-1 error should be nres-1*/
                   7650:            for (i=1; i<= nlstate ; i ++) {
                   7651:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7652:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7653:            }
1.271     brouard  7654:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7655:            for (i=1; i<= nlstate ; i ++) {
                   7656:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7657:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7658:            } 
1.276     brouard  7659:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7660:            for (i=1; i<= nlstate ; i ++) {
                   7661:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7662:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7663:            } 
1.274     brouard  7664:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7665:          } /* end if backprojcast */
1.296     brouard  7666:        } /* end if prevbcast */
1.276     brouard  7667:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7668:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7669:       } /* nres */
1.201     brouard  7670:     } /* k1 */
                   7671:   } /* cpt */
1.235     brouard  7672: 
                   7673:   
1.126     brouard  7674:   /*2 eme*/
1.238     brouard  7675:   for (k1=1; k1<= m ; k1 ++){  
                   7676:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7677:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7678:        continue;
                   7679:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7680:       strcpy(gplotlabel,"(");
1.238     brouard  7681:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7682:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7683:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7684:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7685:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7686:        vlv= nbcode[Tvaraff[k]][lv];
                   7687:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7688:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7689:       }
1.237     brouard  7690:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7691:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7692:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7693:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7694:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7695:       }
1.264     brouard  7696:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7697:       fprintf(ficgp,"\n#\n");
1.223     brouard  7698:       if(invalidvarcomb[k1]){
                   7699:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7700:        continue;
                   7701:       }
1.219     brouard  7702:                        
1.241     brouard  7703:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7704:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7705:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7706:        if(vpopbased==0){
1.238     brouard  7707:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7708:        }else
1.238     brouard  7709:          fprintf(ficgp,"\nreplot ");
                   7710:        for (i=1; i<= nlstate+1 ; i ++) {
                   7711:          k=2*i;
1.261     brouard  7712:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7713:          for (j=1; j<= nlstate+1 ; j ++) {
                   7714:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7715:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7716:          }   
                   7717:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7718:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7719:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7720:          for (j=1; j<= nlstate+1 ; j ++) {
                   7721:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7722:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7723:          }   
                   7724:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7725:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7726:          for (j=1; j<= nlstate+1 ; j ++) {
                   7727:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7728:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7729:          }   
                   7730:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7731:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7732:        } /* state */
                   7733:       } /* vpopbased */
1.264     brouard  7734:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7735:     } /* end nres */
                   7736:   } /* k1 end 2 eme*/
                   7737:        
                   7738:        
                   7739:   /*3eme*/
                   7740:   for (k1=1; k1<= m ; k1 ++){
                   7741:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7742:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7743:        continue;
                   7744: 
                   7745:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7746:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7747:        strcpy(gplotlabel,"(");
1.238     brouard  7748:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7749:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7750:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7751:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7752:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7753:          vlv= nbcode[Tvaraff[k]][lv];
                   7754:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7755:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7756:        }
                   7757:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7758:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7759:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7760:        }       
1.264     brouard  7761:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7762:        fprintf(ficgp,"\n#\n");
                   7763:        if(invalidvarcomb[k1]){
                   7764:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7765:          continue;
                   7766:        }
                   7767:                        
                   7768:        /*       k=2+nlstate*(2*cpt-2); */
                   7769:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7770:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7771:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7772:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7773: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7774:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7775:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7776:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7777:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7778:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7779:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7780:                                
1.238     brouard  7781:        */
                   7782:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7783:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7784:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7785:                                
1.238     brouard  7786:        } 
1.261     brouard  7787:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7788:       }
1.264     brouard  7789:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7790:     } /* end nres */
                   7791:   } /* end kl 3eme */
1.126     brouard  7792:   
1.223     brouard  7793:   /* 4eme */
1.201     brouard  7794:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7795:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7796:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7797:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7798:        continue;
1.238     brouard  7799:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7800:        strcpy(gplotlabel,"(");
1.238     brouard  7801:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7802:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7803:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7804:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7805:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7806:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7807:          vlv= nbcode[Tvaraff[k]][lv];
                   7808:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7809:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7810:        }
                   7811:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7812:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7813:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7814:        }       
1.264     brouard  7815:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7816:        fprintf(ficgp,"\n#\n");
                   7817:        if(invalidvarcomb[k1]){
                   7818:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7819:          continue;
1.223     brouard  7820:        }
1.238     brouard  7821:       
1.241     brouard  7822:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7823:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7824:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7825: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7826:        k=3;
                   7827:        for (i=1; i<= nlstate ; i ++){
                   7828:          if(i==1){
                   7829:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7830:          }else{
                   7831:            fprintf(ficgp,", '' ");
                   7832:          }
                   7833:          l=(nlstate+ndeath)*(i-1)+1;
                   7834:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7835:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7836:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7837:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7838:        } /* nlstate */
1.264     brouard  7839:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7840:       } /* end cpt state*/ 
                   7841:     } /* end nres */
                   7842:   } /* end covariate k1 */  
                   7843: 
1.220     brouard  7844: /* 5eme */
1.201     brouard  7845:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7846:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7847:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7848:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7849:        continue;
1.238     brouard  7850:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7851:        strcpy(gplotlabel,"(");
1.238     brouard  7852:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7853:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7854:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7855:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7856:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7857:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7858:          vlv= nbcode[Tvaraff[k]][lv];
                   7859:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7860:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7861:        }
                   7862:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7863:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7864:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7865:        }       
1.264     brouard  7866:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7867:        fprintf(ficgp,"\n#\n");
                   7868:        if(invalidvarcomb[k1]){
                   7869:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7870:          continue;
                   7871:        }
1.227     brouard  7872:       
1.241     brouard  7873:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7874:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7875:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7876: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7877:        k=3;
                   7878:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7879:          if(j==1)
                   7880:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7881:          else
                   7882:            fprintf(ficgp,", '' ");
                   7883:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7884:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7885:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7886:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7887:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7888:        } /* nlstate */
                   7889:        fprintf(ficgp,", '' ");
                   7890:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7891:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7892:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7893:          if(j < nlstate)
                   7894:            fprintf(ficgp,"$%d +",k+l);
                   7895:          else
                   7896:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7897:        }
1.264     brouard  7898:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7899:       } /* end cpt state*/ 
                   7900:     } /* end covariate */  
                   7901:   } /* end nres */
1.227     brouard  7902:   
1.220     brouard  7903: /* 6eme */
1.202     brouard  7904:   /* CV preval stable (period) for each covariate */
1.237     brouard  7905:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7906:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7907:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7908:       continue;
1.255     brouard  7909:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7910:       strcpy(gplotlabel,"(");      
1.288     brouard  7911:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7912:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7913:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7914:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7915:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7916:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7917:        vlv= nbcode[Tvaraff[k]][lv];
                   7918:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7919:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7920:       }
1.237     brouard  7921:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7922:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7923:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7924:       }        
1.264     brouard  7925:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7926:       fprintf(ficgp,"\n#\n");
1.223     brouard  7927:       if(invalidvarcomb[k1]){
1.227     brouard  7928:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7929:        continue;
1.223     brouard  7930:       }
1.227     brouard  7931:       
1.241     brouard  7932:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7933:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7934:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7935: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7936:       k=3; /* Offset */
1.255     brouard  7937:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7938:        if(i==1)
                   7939:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7940:        else
                   7941:          fprintf(ficgp,", '' ");
1.255     brouard  7942:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7943:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7944:        for (j=2; j<= nlstate ; j ++)
                   7945:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7946:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7947:       } /* nlstate */
1.264     brouard  7948:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7949:     } /* end cpt state*/ 
                   7950:   } /* end covariate */  
1.227     brouard  7951:   
                   7952:   
1.220     brouard  7953: /* 7eme */
1.296     brouard  7954:   if(prevbcast == 1){
1.288     brouard  7955:     /* CV backward prevalence  for each covariate */
1.237     brouard  7956:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7957:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7958:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7959:        continue;
1.268     brouard  7960:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7961:        strcpy(gplotlabel,"(");      
1.288     brouard  7962:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7963:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7964:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7965:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7966:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7967:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7968:          vlv= nbcode[Tvaraff[k]][lv];
                   7969:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7970:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7971:        }
1.237     brouard  7972:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7973:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7974:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7975:        }       
1.264     brouard  7976:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7977:        fprintf(ficgp,"\n#\n");
                   7978:        if(invalidvarcomb[k1]){
                   7979:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7980:          continue;
                   7981:        }
                   7982:        
1.241     brouard  7983:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7984:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7985:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7986: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7987:        k=3; /* Offset */
1.268     brouard  7988:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7989:          if(i==1)
                   7990:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7991:          else
                   7992:            fprintf(ficgp,", '' ");
                   7993:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7994:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7995:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7996:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7997:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7998:          /* for (j=2; j<= nlstate ; j ++) */
                   7999:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   8000:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  8001:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  8002:        } /* nlstate */
1.264     brouard  8003:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  8004:       } /* end cpt state*/ 
                   8005:     } /* end covariate */  
1.296     brouard  8006:   } /* End if prevbcast */
1.218     brouard  8007:   
1.223     brouard  8008:   /* 8eme */
1.218     brouard  8009:   if(prevfcast==1){
1.288     brouard  8010:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  8011:     
1.237     brouard  8012:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   8013:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  8014:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  8015:        continue;
1.211     brouard  8016:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  8017:        strcpy(gplotlabel,"(");      
1.288     brouard  8018:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  8019:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8020:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8021:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8022:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8023:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8024:          vlv= nbcode[Tvaraff[k]][lv];
                   8025:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  8026:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  8027:        }
1.237     brouard  8028:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8029:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  8030:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  8031:        }       
1.264     brouard  8032:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  8033:        fprintf(ficgp,"\n#\n");
                   8034:        if(invalidvarcomb[k1]){
                   8035:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   8036:          continue;
                   8037:        }
                   8038:        
                   8039:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  8040:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  8041:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  8042:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  8043: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  8044: 
                   8045:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   8046:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8047:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8048:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  8049:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8050:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   8051:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8052:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  8053:          if(i==istart){
1.227     brouard  8054:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   8055:          }else{
                   8056:            fprintf(ficgp,",\\\n '' ");
                   8057:          }
                   8058:          if(cptcoveff ==0){ /* No covariate */
                   8059:            ioffset=2; /* Age is in 2 */
                   8060:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8061:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8062:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8063:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8064:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  8065:            if(i==nlstate+1){
1.270     brouard  8066:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  8067:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   8068:              fprintf(ficgp,",\\\n '' ");
                   8069:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  8070:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  8071:                     offyear,                           \
1.268     brouard  8072:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  8073:            }else
1.227     brouard  8074:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   8075:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   8076:          }else{ /* more than 2 covariates */
1.270     brouard  8077:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   8078:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8079:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   8080:            iyearc=ioffset-1;
                   8081:            iagec=ioffset;
1.227     brouard  8082:            fprintf(ficgp," u %d:(",ioffset); 
                   8083:            kl=0;
                   8084:            strcpy(gplotcondition,"(");
                   8085:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   8086:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   8087:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8088:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8089:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8090:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   8091:              kl++;
                   8092:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   8093:              kl++;
                   8094:              if(k <cptcoveff && cptcoveff>1)
                   8095:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   8096:            }
                   8097:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   8098:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   8099:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   8100:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   8101:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   8102:            if(i==nlstate+1){
1.270     brouard  8103:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   8104:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  8105:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  8106:              fprintf(ficgp," u %d:(",iagec); 
                   8107:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   8108:                      iyearc, iagec, offyear,                           \
                   8109:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  8110: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  8111:            }else{
                   8112:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   8113:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   8114:            }
                   8115:          } /* end if covariate */
                   8116:        } /* nlstate */
1.264     brouard  8117:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  8118:       } /* end cpt state*/
                   8119:     } /* end covariate */
                   8120:   } /* End if prevfcast */
1.227     brouard  8121:   
1.296     brouard  8122:   if(prevbcast==1){
1.268     brouard  8123:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   8124:     
                   8125:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   8126:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   8127:       if(m != 1 && TKresult[nres]!= k1)
                   8128:        continue;
                   8129:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   8130:        strcpy(gplotlabel,"(");      
                   8131:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   8132:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8133:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8134:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8135:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8136:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8137:          vlv= nbcode[Tvaraff[k]][lv];
                   8138:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   8139:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   8140:        }
                   8141:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8142:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8143:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8144:        }       
                   8145:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   8146:        fprintf(ficgp,"\n#\n");
                   8147:        if(invalidvarcomb[k1]){
                   8148:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   8149:          continue;
                   8150:        }
                   8151:        
                   8152:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   8153:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   8154:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   8155:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   8156: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   8157: 
                   8158:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   8159:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8160:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8161:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   8162:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8163:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   8164:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8165:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   8166:          if(i==istart){
                   8167:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   8168:          }else{
                   8169:            fprintf(ficgp,",\\\n '' ");
                   8170:          }
                   8171:          if(cptcoveff ==0){ /* No covariate */
                   8172:            ioffset=2; /* Age is in 2 */
                   8173:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8174:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8175:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8176:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8177:            fprintf(ficgp," u %d:(", ioffset); 
                   8178:            if(i==nlstate+1){
1.270     brouard  8179:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  8180:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   8181:              fprintf(ficgp,",\\\n '' ");
                   8182:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  8183:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  8184:                     offbyear,                          \
                   8185:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   8186:            }else
                   8187:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   8188:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   8189:          }else{ /* more than 2 covariates */
1.270     brouard  8190:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   8191:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8192:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   8193:            iyearc=ioffset-1;
                   8194:            iagec=ioffset;
1.268     brouard  8195:            fprintf(ficgp," u %d:(",ioffset); 
                   8196:            kl=0;
                   8197:            strcpy(gplotcondition,"(");
                   8198:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   8199:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   8200:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8201:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8202:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8203:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   8204:              kl++;
                   8205:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   8206:              kl++;
                   8207:              if(k <cptcoveff && cptcoveff>1)
                   8208:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   8209:            }
                   8210:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   8211:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   8212:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   8213:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   8214:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   8215:            if(i==nlstate+1){
1.270     brouard  8216:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   8217:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  8218:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  8219:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  8220:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  8221:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   8222:                      iyearc,iagec,offbyear,                            \
                   8223:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  8224: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   8225:            }else{
                   8226:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   8227:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   8228:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   8229:            }
                   8230:          } /* end if covariate */
                   8231:        } /* nlstate */
                   8232:        fprintf(ficgp,"\nset out; unset label;\n");
                   8233:       } /* end cpt state*/
                   8234:     } /* end covariate */
1.296     brouard  8235:   } /* End if prevbcast */
1.268     brouard  8236:   
1.227     brouard  8237:   
1.238     brouard  8238:   /* 9eme writing MLE parameters */
                   8239:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  8240:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  8241:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  8242:     for(k=1; k <=(nlstate+ndeath); k++){
                   8243:       if (k != i) {
1.227     brouard  8244:        fprintf(ficgp,"#   current state %d\n",k);
                   8245:        for(j=1; j <=ncovmodel; j++){
                   8246:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   8247:          jk++; 
                   8248:        }
                   8249:        fprintf(ficgp,"\n");
1.126     brouard  8250:       }
                   8251:     }
1.223     brouard  8252:   }
1.187     brouard  8253:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  8254:   
1.145     brouard  8255:   /*goto avoid;*/
1.238     brouard  8256:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   8257:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  8258:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   8259:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   8260:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   8261:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   8262:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8263:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8264:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8265:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8266:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   8267:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8268:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   8269:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   8270:   fprintf(ficgp,"#\n");
1.223     brouard  8271:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  8272:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  8273:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  8274:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  8275:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   8276:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  8277:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  8278:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  8279:        continue;
1.264     brouard  8280:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   8281:       strcpy(gplotlabel,"(");
1.276     brouard  8282:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  8283:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8284:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8285:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8286:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8287:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8288:        vlv= nbcode[Tvaraff[k]][lv];
                   8289:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   8290:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   8291:       }
1.237     brouard  8292:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8293:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  8294:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  8295:       }        
1.264     brouard  8296:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  8297:       fprintf(ficgp,"\n#\n");
1.264     brouard  8298:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  8299:       fprintf(ficgp,"\nset key outside ");
                   8300:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   8301:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  8302:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   8303:       if (ng==1){
                   8304:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   8305:        fprintf(ficgp,"\nunset log y");
                   8306:       }else if (ng==2){
                   8307:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   8308:        fprintf(ficgp,"\nset log y");
                   8309:       }else if (ng==3){
                   8310:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   8311:        fprintf(ficgp,"\nset log y");
                   8312:       }else
                   8313:        fprintf(ficgp,"\nunset title ");
                   8314:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   8315:       i=1;
                   8316:       for(k2=1; k2<=nlstate; k2++) {
                   8317:        k3=i;
                   8318:        for(k=1; k<=(nlstate+ndeath); k++) {
                   8319:          if (k != k2){
                   8320:            switch( ng) {
                   8321:            case 1:
                   8322:              if(nagesqr==0)
                   8323:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   8324:              else /* nagesqr =1 */
                   8325:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8326:              break;
                   8327:            case 2: /* ng=2 */
                   8328:              if(nagesqr==0)
                   8329:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   8330:              else /* nagesqr =1 */
                   8331:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8332:              break;
                   8333:            case 3:
                   8334:              if(nagesqr==0)
                   8335:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   8336:              else /* nagesqr =1 */
                   8337:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   8338:              break;
                   8339:            }
                   8340:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  8341:            ijp=1; /* product no age */
                   8342:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   8343:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  8344:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  8345:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8346:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   8347:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8348:                    if(DummyV[j]==0){
                   8349:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   8350:                    }else{ /* quantitative */
                   8351:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   8352:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8353:                    }
                   8354:                    ij++;
1.237     brouard  8355:                  }
1.268     brouard  8356:                } 
                   8357:              }else if(cptcovprod >0){
                   8358:                if(j==Tprod[ijp]) { /* */ 
                   8359:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   8360:                  if(ijp <=cptcovprod) { /* Product */
                   8361:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   8362:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   8363:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   8364:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   8365:                      }else{ /* Vn is dummy and Vm is quanti */
                   8366:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   8367:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8368:                      }
                   8369:                    }else{ /* Vn*Vm Vn is quanti */
                   8370:                      if(DummyV[Tvard[ijp][2]]==0){
                   8371:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   8372:                      }else{ /* Both quanti */
                   8373:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8374:                      }
1.237     brouard  8375:                    }
1.268     brouard  8376:                    ijp++;
1.237     brouard  8377:                  }
1.268     brouard  8378:                } /* end Tprod */
1.237     brouard  8379:              } else{  /* simple covariate */
1.264     brouard  8380:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  8381:                if(Dummy[j]==0){
                   8382:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   8383:                }else{ /* quantitative */
                   8384:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  8385:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  8386:                }
1.237     brouard  8387:              } /* end simple */
                   8388:            } /* end j */
1.223     brouard  8389:          }else{
                   8390:            i=i-ncovmodel;
                   8391:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   8392:              fprintf(ficgp," (1.");
                   8393:          }
1.227     brouard  8394:          
1.223     brouard  8395:          if(ng != 1){
                   8396:            fprintf(ficgp,")/(1");
1.227     brouard  8397:            
1.264     brouard  8398:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8399:              if(nagesqr==0)
1.264     brouard  8400:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8401:              else /* nagesqr =1 */
1.264     brouard  8402:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8403:               
1.223     brouard  8404:              ij=1;
                   8405:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8406:                 if(cptcovage >0){ 
                   8407:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8408:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8409:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8410:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8411:                       ij++;
                   8412:                     }
                   8413:                   }
                   8414:                 }else
                   8415:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8416:              }
                   8417:              fprintf(ficgp,")");
                   8418:            }
                   8419:            fprintf(ficgp,")");
                   8420:            if(ng ==2)
1.276     brouard  8421:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8422:            else /* ng= 3 */
1.276     brouard  8423:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8424:          }else{ /* end ng <> 1 */
                   8425:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8426:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8427:          }
                   8428:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8429:            fprintf(ficgp,",");
                   8430:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8431:            fprintf(ficgp,",");
                   8432:          i=i+ncovmodel;
                   8433:        } /* end k */
                   8434:       } /* end k2 */
1.276     brouard  8435:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8436:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8437:     } /* end k1 */
1.223     brouard  8438:   } /* end ng */
                   8439:   /* avoid: */
                   8440:   fflush(ficgp); 
1.126     brouard  8441: }  /* end gnuplot */
                   8442: 
                   8443: 
                   8444: /*************** Moving average **************/
1.219     brouard  8445: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8446:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8447:    
1.222     brouard  8448:    int i, cpt, cptcod;
                   8449:    int modcovmax =1;
                   8450:    int mobilavrange, mob;
                   8451:    int iage=0;
1.288     brouard  8452:    int firstA1=0, firstA2=0;
1.222     brouard  8453: 
1.266     brouard  8454:    double sum=0., sumr=0.;
1.222     brouard  8455:    double age;
1.266     brouard  8456:    double *sumnewp, *sumnewm, *sumnewmr;
                   8457:    double *agemingood, *agemaxgood; 
                   8458:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8459:   
                   8460:   
1.278     brouard  8461:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8462:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8463: 
                   8464:    sumnewp = vector(1,ncovcombmax);
                   8465:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8466:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8467:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8468:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8469:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8470:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8471: 
                   8472:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8473:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8474:      sumnewp[cptcod]=0.;
1.266     brouard  8475:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8476:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8477:    }
                   8478:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8479:   
1.266     brouard  8480:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8481:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8482:      else mobilavrange=mobilav;
                   8483:      for (age=bage; age<=fage; age++)
                   8484:        for (i=1; i<=nlstate;i++)
                   8485:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8486:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8487:      /* We keep the original values on the extreme ages bage, fage and for 
                   8488:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8489:        we use a 5 terms etc. until the borders are no more concerned. 
                   8490:      */ 
                   8491:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8492:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8493:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8494:           sumnewm[cptcod]=0.;
                   8495:           for (i=1; i<=nlstate;i++){
1.222     brouard  8496:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8497:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8498:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8499:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8500:             }
                   8501:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8502:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8503:           } /* end i */
                   8504:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8505:         } /* end cptcod */
1.222     brouard  8506:        }/* end age */
                   8507:      }/* end mob */
1.266     brouard  8508:    }else{
                   8509:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8510:      return -1;
1.266     brouard  8511:    }
                   8512: 
                   8513:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8514:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8515:      if(invalidvarcomb[cptcod]){
                   8516:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8517:        continue;
                   8518:      }
1.219     brouard  8519: 
1.266     brouard  8520:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8521:        sumnewm[cptcod]=0.;
                   8522:        sumnewmr[cptcod]=0.;
                   8523:        for (i=1; i<=nlstate;i++){
                   8524:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8525:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8526:        }
                   8527:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8528:         agemingoodr[cptcod]=age;
                   8529:        }
                   8530:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8531:           agemingood[cptcod]=age;
                   8532:        }
                   8533:      } /* age */
                   8534:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8535:        sumnewm[cptcod]=0.;
1.266     brouard  8536:        sumnewmr[cptcod]=0.;
1.222     brouard  8537:        for (i=1; i<=nlstate;i++){
                   8538:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8539:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8540:        }
                   8541:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8542:         agemaxgoodr[cptcod]=age;
1.222     brouard  8543:        }
                   8544:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8545:         agemaxgood[cptcod]=age;
                   8546:        }
                   8547:      } /* age */
                   8548:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8549:      /* but they will change */
1.288     brouard  8550:      firstA1=0;firstA2=0;
1.266     brouard  8551:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8552:        sumnewm[cptcod]=0.;
                   8553:        sumnewmr[cptcod]=0.;
                   8554:        for (i=1; i<=nlstate;i++){
                   8555:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8556:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8557:        }
                   8558:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8559:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8560:           agemaxgoodr[cptcod]=age;  /* age min */
                   8561:           for (i=1; i<=nlstate;i++)
                   8562:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8563:         }else{ /* bad we change the value with the values of good ages */
                   8564:           for (i=1; i<=nlstate;i++){
                   8565:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8566:           } /* i */
                   8567:         } /* end bad */
                   8568:        }else{
                   8569:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8570:           agemaxgood[cptcod]=age;
                   8571:         }else{ /* bad we change the value with the values of good ages */
                   8572:           for (i=1; i<=nlstate;i++){
                   8573:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8574:           } /* i */
                   8575:         } /* end bad */
                   8576:        }/* end else */
                   8577:        sum=0.;sumr=0.;
                   8578:        for (i=1; i<=nlstate;i++){
                   8579:         sum+=mobaverage[(int)age][i][cptcod];
                   8580:         sumr+=probs[(int)age][i][cptcod];
                   8581:        }
                   8582:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8583:         if(!firstA1){
                   8584:           firstA1=1;
                   8585:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8586:         }
                   8587:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8588:        } /* end bad */
                   8589:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8590:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8591:         if(!firstA2){
                   8592:           firstA2=1;
                   8593:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8594:         }
                   8595:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8596:        } /* end bad */
                   8597:      }/* age */
1.266     brouard  8598: 
                   8599:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8600:        sumnewm[cptcod]=0.;
1.266     brouard  8601:        sumnewmr[cptcod]=0.;
1.222     brouard  8602:        for (i=1; i<=nlstate;i++){
                   8603:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8604:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8605:        } 
                   8606:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8607:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8608:           agemingoodr[cptcod]=age;
                   8609:           for (i=1; i<=nlstate;i++)
                   8610:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8611:         }else{ /* bad we change the value with the values of good ages */
                   8612:           for (i=1; i<=nlstate;i++){
                   8613:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8614:           } /* i */
                   8615:         } /* end bad */
                   8616:        }else{
                   8617:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8618:           agemingood[cptcod]=age;
                   8619:         }else{ /* bad */
                   8620:           for (i=1; i<=nlstate;i++){
                   8621:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8622:           } /* i */
                   8623:         } /* end bad */
                   8624:        }/* end else */
                   8625:        sum=0.;sumr=0.;
                   8626:        for (i=1; i<=nlstate;i++){
                   8627:         sum+=mobaverage[(int)age][i][cptcod];
                   8628:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8629:        }
1.266     brouard  8630:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8631:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8632:        } /* end bad */
                   8633:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8634:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8635:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8636:        } /* end bad */
                   8637:      }/* age */
1.266     brouard  8638: 
1.222     brouard  8639:                
                   8640:      for (age=bage; age<=fage; age++){
1.235     brouard  8641:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8642:        sumnewp[cptcod]=0.;
                   8643:        sumnewm[cptcod]=0.;
                   8644:        for (i=1; i<=nlstate;i++){
                   8645:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8646:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8647:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8648:        }
                   8649:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8650:      }
                   8651:      /* printf("\n"); */
                   8652:      /* } */
1.266     brouard  8653: 
1.222     brouard  8654:      /* brutal averaging */
1.266     brouard  8655:      /* for (i=1; i<=nlstate;i++){ */
                   8656:      /*   for (age=1; age<=bage; age++){ */
                   8657:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8658:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8659:      /*   }     */
                   8660:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8661:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8662:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8663:      /*   } */
                   8664:      /* } /\* end i status *\/ */
                   8665:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8666:      /*   for (age=1; age<=AGESUP; age++){ */
                   8667:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8668:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8669:      /*   } */
                   8670:      /* } */
1.222     brouard  8671:    }/* end cptcod */
1.266     brouard  8672:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8673:    free_vector(agemaxgood,1, ncovcombmax);
                   8674:    free_vector(agemingood,1, ncovcombmax);
                   8675:    free_vector(agemingoodr,1, ncovcombmax);
                   8676:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8677:    free_vector(sumnewm,1, ncovcombmax);
                   8678:    free_vector(sumnewp,1, ncovcombmax);
                   8679:    return 0;
                   8680:  }/* End movingaverage */
1.218     brouard  8681:  
1.126     brouard  8682: 
1.296     brouard  8683:  
1.126     brouard  8684: /************** Forecasting ******************/
1.296     brouard  8685: /* void prevforecast(char fileres[], double dateintmean, double anprojd, double mprojd, double jprojd, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anprojf, double p[], int cptcoveff)*/
                   8686: void prevforecast(char fileres[], double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8687:   /* dateintemean, mean date of interviews
                   8688:      dateprojd, year, month, day of starting projection 
                   8689:      dateprojf date of end of projection;year of end of projection (same day and month as proj1).
1.126     brouard  8690:      agemin, agemax range of age
                   8691:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8692:   */
1.296     brouard  8693:   /* double anprojd, mprojd, jprojd; */
                   8694:   /* double anprojf, mprojf, jprojf; */
1.267     brouard  8695:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8696:   double agec; /* generic age */
1.296     brouard  8697:   double agelim, ppij, yp,yp1,yp2;
1.126     brouard  8698:   double *popeffectif,*popcount;
                   8699:   double ***p3mat;
1.218     brouard  8700:   /* double ***mobaverage; */
1.126     brouard  8701:   char fileresf[FILENAMELENGTH];
                   8702: 
                   8703:   agelim=AGESUP;
1.211     brouard  8704:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8705:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8706:      We still use firstpass and lastpass as another selection.
                   8707:   */
1.214     brouard  8708:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8709:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8710:  
1.201     brouard  8711:   strcpy(fileresf,"F_"); 
                   8712:   strcat(fileresf,fileresu);
1.126     brouard  8713:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8714:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8715:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8716:   }
1.235     brouard  8717:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8718:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8719: 
1.225     brouard  8720:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8721: 
                   8722: 
                   8723:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8724:   if (stepm<=12) stepsize=1;
                   8725:   if(estepm < stepm){
                   8726:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8727:   }
1.270     brouard  8728:   else{
                   8729:     hstepm=estepm;   
                   8730:   }
                   8731:   if(estepm > stepm){ /* Yes every two year */
                   8732:     stepsize=2;
                   8733:   }
1.296     brouard  8734:   hstepm=hstepm/stepm;
1.126     brouard  8735: 
1.296     brouard  8736:   
                   8737:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8738:   /*                              fractional in yp1 *\/ */
                   8739:   /* aintmean=yp; */
                   8740:   /* yp2=modf((yp1*12),&yp); */
                   8741:   /* mintmean=yp; */
                   8742:   /* yp1=modf((yp2*30.5),&yp); */
                   8743:   /* jintmean=yp; */
                   8744:   /* if(jintmean==0) jintmean=1; */
                   8745:   /* if(mintmean==0) mintmean=1; */
1.126     brouard  8746: 
1.296     brouard  8747: 
                   8748:   /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */
                   8749:   /* date2dmy(dateprojd,&jprojd, &mprojd, &anprojd); */
                   8750:   /* date2dmy(dateprojf,&jprojf, &mprojf, &anprojf); */
1.227     brouard  8751:   i1=pow(2,cptcoveff);
1.126     brouard  8752:   if (cptcovn < 1){i1=1;}
                   8753:   
1.296     brouard  8754:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2); 
1.126     brouard  8755:   
                   8756:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8757:   
1.126     brouard  8758: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8759:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8760:   for(k=1; k<=i1;k++){
1.253     brouard  8761:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8762:       continue;
1.227     brouard  8763:     if(invalidvarcomb[k]){
                   8764:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8765:       continue;
                   8766:     }
                   8767:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8768:     for(j=1;j<=cptcoveff;j++) {
                   8769:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8770:     }
1.235     brouard  8771:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8772:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8773:     }
1.227     brouard  8774:     fprintf(ficresf," yearproj age");
                   8775:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8776:       for(i=1; i<=nlstate;i++)               
                   8777:        fprintf(ficresf," p%d%d",i,j);
                   8778:       fprintf(ficresf," wp.%d",j);
                   8779:     }
1.296     brouard  8780:     for (yearp=0; yearp<=(anprojf-anprojd);yearp +=stepsize) {
1.227     brouard  8781:       fprintf(ficresf,"\n");
1.296     brouard  8782:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jprojd,mprojd,anprojd+yearp);   
1.270     brouard  8783:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8784:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8785:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8786:        nhstepm = nhstepm/hstepm; 
                   8787:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8788:        oldm=oldms;savm=savms;
1.268     brouard  8789:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8790:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8791:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8792:        for (h=0; h<=nhstepm; h++){
                   8793:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8794:            break;
                   8795:          }
                   8796:        }
                   8797:        fprintf(ficresf,"\n");
                   8798:        for(j=1;j<=cptcoveff;j++) 
                   8799:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8800:        fprintf(ficresf,"%.f %.f ",anprojd+yearp,agec+h*hstepm/YEARM*stepm);
1.268     brouard  8801:        
                   8802:        for(j=1; j<=nlstate+ndeath;j++) {
                   8803:          ppij=0.;
                   8804:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8805:            if (mobilav>=1)
                   8806:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8807:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8808:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8809:            }
1.268     brouard  8810:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8811:          } /* end i */
                   8812:          fprintf(ficresf," %.3f", ppij);
                   8813:        }/* end j */
1.227     brouard  8814:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8815:       } /* end agec */
1.266     brouard  8816:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8817:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8818:     } /* end yearp */
                   8819:   } /* end  k */
1.219     brouard  8820:        
1.126     brouard  8821:   fclose(ficresf);
1.215     brouard  8822:   printf("End of Computing forecasting \n");
                   8823:   fprintf(ficlog,"End of Computing forecasting\n");
                   8824: 
1.126     brouard  8825: }
                   8826: 
1.269     brouard  8827: /************** Back Forecasting ******************/
1.296     brouard  8828:  /* void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
                   8829:  void prevbackforecast(char fileres[], double ***prevacurrent, double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8830:   /* back1, year, month, day of starting backprojection
1.267     brouard  8831:      agemin, agemax range of age
                   8832:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8833:      anback2 year of end of backprojection (same day and month as back1).
                   8834:      prevacurrent and prev are prevalences.
1.267     brouard  8835:   */
                   8836:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8837:   double agec; /* generic age */
1.302     brouard  8838:   double agelim, ppij, ppi, yp,yp1,yp2; /* ,jintmean,mintmean,aintmean;*/
1.267     brouard  8839:   double *popeffectif,*popcount;
                   8840:   double ***p3mat;
                   8841:   /* double ***mobaverage; */
                   8842:   char fileresfb[FILENAMELENGTH];
                   8843:  
1.268     brouard  8844:   agelim=AGEINF;
1.267     brouard  8845:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8846:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8847:      We still use firstpass and lastpass as another selection.
                   8848:   */
                   8849:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8850:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8851: 
                   8852:   /*Do we need to compute prevalence again?*/
                   8853: 
                   8854:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8855:   
                   8856:   strcpy(fileresfb,"FB_");
                   8857:   strcat(fileresfb,fileresu);
                   8858:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8859:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8860:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8861:   }
                   8862:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8863:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8864:   
                   8865:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8866:   
                   8867:    
                   8868:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8869:   if (stepm<=12) stepsize=1;
                   8870:   if(estepm < stepm){
                   8871:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8872:   }
1.270     brouard  8873:   else{
                   8874:     hstepm=estepm;   
                   8875:   }
                   8876:   if(estepm >= stepm){ /* Yes every two year */
                   8877:     stepsize=2;
                   8878:   }
1.267     brouard  8879:   
                   8880:   hstepm=hstepm/stepm;
1.296     brouard  8881:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8882:   /*                              fractional in yp1 *\/ */
                   8883:   /* aintmean=yp; */
                   8884:   /* yp2=modf((yp1*12),&yp); */
                   8885:   /* mintmean=yp; */
                   8886:   /* yp1=modf((yp2*30.5),&yp); */
                   8887:   /* jintmean=yp; */
                   8888:   /* if(jintmean==0) jintmean=1; */
                   8889:   /* if(mintmean==0) jintmean=1; */
1.267     brouard  8890:   
                   8891:   i1=pow(2,cptcoveff);
                   8892:   if (cptcovn < 1){i1=1;}
                   8893:   
1.296     brouard  8894:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
                   8895:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8896:   
                   8897:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8898:   
                   8899:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8900:   for(k=1; k<=i1;k++){
                   8901:     if(i1 != 1 && TKresult[nres]!= k)
                   8902:       continue;
                   8903:     if(invalidvarcomb[k]){
                   8904:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8905:       continue;
                   8906:     }
1.268     brouard  8907:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8908:     for(j=1;j<=cptcoveff;j++) {
                   8909:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8910:     }
                   8911:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8912:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8913:     }
                   8914:     fprintf(ficresfb," yearbproj age");
                   8915:     for(j=1; j<=nlstate+ndeath;j++){
                   8916:       for(i=1; i<=nlstate;i++)
1.268     brouard  8917:        fprintf(ficresfb," b%d%d",i,j);
                   8918:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8919:     }
1.296     brouard  8920:     for (yearp=0; yearp>=(anbackf-anbackd);yearp -=stepsize) {
1.267     brouard  8921:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8922:       fprintf(ficresfb,"\n");
1.296     brouard  8923:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jbackd,mbackd,anbackd+yearp);
1.273     brouard  8924:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8925:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8926:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8927:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8928:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8929:        nhstepm = nhstepm/hstepm;
                   8930:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8931:        oldm=oldms;savm=savms;
1.268     brouard  8932:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8933:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8934:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8935:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8936:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8937:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8938:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8939:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8940:            break;
                   8941:          }
                   8942:        }
                   8943:        fprintf(ficresfb,"\n");
                   8944:        for(j=1;j<=cptcoveff;j++)
                   8945:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8946:        fprintf(ficresfb,"%.f %.f ",anbackd+yearp,agec-h*hstepm/YEARM*stepm);
1.268     brouard  8947:        for(i=1; i<=nlstate+ndeath;i++) {
                   8948:          ppij=0.;ppi=0.;
                   8949:          for(j=1; j<=nlstate;j++) {
                   8950:            /* if (mobilav==1) */
1.269     brouard  8951:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8952:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8953:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8954:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8955:              /* else { */
                   8956:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8957:              /* } */
1.268     brouard  8958:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8959:          } /* end j */
                   8960:          if(ppi <0.99){
                   8961:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8962:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8963:          }
                   8964:          fprintf(ficresfb," %.3f", ppij);
                   8965:        }/* end j */
1.267     brouard  8966:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8967:       } /* end agec */
                   8968:     } /* end yearp */
                   8969:   } /* end k */
1.217     brouard  8970:   
1.267     brouard  8971:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8972:   
1.267     brouard  8973:   fclose(ficresfb);
                   8974:   printf("End of Computing Back forecasting \n");
                   8975:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8976:        
1.267     brouard  8977: }
1.217     brouard  8978: 
1.269     brouard  8979: /* Variance of prevalence limit: varprlim */
                   8980:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8981:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8982:  
                   8983:    char fileresvpl[FILENAMELENGTH];  
                   8984:    FILE *ficresvpl;
                   8985:    double **oldm, **savm;
                   8986:    double **varpl; /* Variances of prevalence limits by age */   
                   8987:    int i1, k, nres, j ;
                   8988:    
                   8989:     strcpy(fileresvpl,"VPL_");
                   8990:     strcat(fileresvpl,fileresu);
                   8991:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8992:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8993:       exit(0);
                   8994:     }
1.288     brouard  8995:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8996:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8997:     
                   8998:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8999:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   9000:     
                   9001:     i1=pow(2,cptcoveff);
                   9002:     if (cptcovn < 1){i1=1;}
                   9003: 
                   9004:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9005:     for(k=1; k<=i1;k++){
                   9006:       if(i1 != 1 && TKresult[nres]!= k)
                   9007:        continue;
                   9008:       fprintf(ficresvpl,"\n#****** ");
                   9009:       printf("\n#****** ");
                   9010:       fprintf(ficlog,"\n#****** ");
                   9011:       for(j=1;j<=cptcoveff;j++) {
                   9012:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9013:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9014:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9015:       }
                   9016:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9017:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9018:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9019:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9020:       }        
                   9021:       fprintf(ficresvpl,"******\n");
                   9022:       printf("******\n");
                   9023:       fprintf(ficlog,"******\n");
                   9024:       
                   9025:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   9026:       oldm=oldms;savm=savms;
                   9027:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   9028:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   9029:       /*}*/
                   9030:     }
                   9031:     
                   9032:     fclose(ficresvpl);
1.288     brouard  9033:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   9034:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  9035: 
                   9036:  }
                   9037: /* Variance of back prevalence: varbprlim */
                   9038:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   9039:       /*------- Variance of back (stable) prevalence------*/
                   9040: 
                   9041:    char fileresvbl[FILENAMELENGTH];  
                   9042:    FILE  *ficresvbl;
                   9043: 
                   9044:    double **oldm, **savm;
                   9045:    double **varbpl; /* Variances of back prevalence limits by age */   
                   9046:    int i1, k, nres, j ;
                   9047: 
                   9048:    strcpy(fileresvbl,"VBL_");
                   9049:    strcat(fileresvbl,fileresu);
                   9050:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   9051:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   9052:      exit(0);
                   9053:    }
                   9054:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   9055:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   9056:    
                   9057:    
                   9058:    i1=pow(2,cptcoveff);
                   9059:    if (cptcovn < 1){i1=1;}
                   9060:    
                   9061:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9062:      for(k=1; k<=i1;k++){
                   9063:        if(i1 != 1 && TKresult[nres]!= k)
                   9064:         continue;
                   9065:        fprintf(ficresvbl,"\n#****** ");
                   9066:        printf("\n#****** ");
                   9067:        fprintf(ficlog,"\n#****** ");
                   9068:        for(j=1;j<=cptcoveff;j++) {
                   9069:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9070:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9071:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9072:        }
                   9073:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9074:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9075:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9076:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9077:        }
                   9078:        fprintf(ficresvbl,"******\n");
                   9079:        printf("******\n");
                   9080:        fprintf(ficlog,"******\n");
                   9081:        
                   9082:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   9083:        oldm=oldms;savm=savms;
                   9084:        
                   9085:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   9086:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   9087:        /*}*/
                   9088:      }
                   9089:    
                   9090:    fclose(ficresvbl);
                   9091:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   9092:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   9093: 
                   9094:  } /* End of varbprlim */
                   9095: 
1.126     brouard  9096: /************** Forecasting *****not tested NB*************/
1.227     brouard  9097: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  9098:   
1.227     brouard  9099: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   9100: /*   int *popage; */
                   9101: /*   double calagedatem, agelim, kk1, kk2; */
                   9102: /*   double *popeffectif,*popcount; */
                   9103: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   9104: /*   /\* double ***mobaverage; *\/ */
                   9105: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  9106: 
1.227     brouard  9107: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9108: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9109: /*   agelim=AGESUP; */
                   9110: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  9111:   
1.227     brouard  9112: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  9113:   
                   9114:   
1.227     brouard  9115: /*   strcpy(filerespop,"POP_");  */
                   9116: /*   strcat(filerespop,fileresu); */
                   9117: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   9118: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   9119: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   9120: /*   } */
                   9121: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   9122: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  9123: 
1.227     brouard  9124: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  9125: 
1.227     brouard  9126: /*   /\* if (mobilav!=0) { *\/ */
                   9127: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   9128: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   9129: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   9130: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   9131: /*   /\*   } *\/ */
                   9132: /*   /\* } *\/ */
1.126     brouard  9133: 
1.227     brouard  9134: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   9135: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  9136:   
1.227     brouard  9137: /*   agelim=AGESUP; */
1.126     brouard  9138:   
1.227     brouard  9139: /*   hstepm=1; */
                   9140: /*   hstepm=hstepm/stepm;  */
1.218     brouard  9141:        
1.227     brouard  9142: /*   if (popforecast==1) { */
                   9143: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   9144: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   9145: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   9146: /*     }  */
                   9147: /*     popage=ivector(0,AGESUP); */
                   9148: /*     popeffectif=vector(0,AGESUP); */
                   9149: /*     popcount=vector(0,AGESUP); */
1.126     brouard  9150:     
1.227     brouard  9151: /*     i=1;    */
                   9152: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  9153:     
1.227     brouard  9154: /*     imx=i; */
                   9155: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   9156: /*   } */
1.218     brouard  9157:   
1.227     brouard  9158: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   9159: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   9160: /*       k=k+1; */
                   9161: /*       fprintf(ficrespop,"\n#******"); */
                   9162: /*       for(j=1;j<=cptcoveff;j++) { */
                   9163: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   9164: /*       } */
                   9165: /*       fprintf(ficrespop,"******\n"); */
                   9166: /*       fprintf(ficrespop,"# Age"); */
                   9167: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   9168: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  9169:       
1.227     brouard  9170: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   9171: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  9172:        
1.227     brouard  9173: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   9174: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   9175: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  9176:          
1.227     brouard  9177: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9178: /*       oldm=oldms;savm=savms; */
                   9179: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  9180:          
1.227     brouard  9181: /*       for (h=0; h<=nhstepm; h++){ */
                   9182: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   9183: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   9184: /*         }  */
                   9185: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   9186: /*           kk1=0.;kk2=0; */
                   9187: /*           for(i=1; i<=nlstate;i++) {               */
                   9188: /*             if (mobilav==1)  */
                   9189: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   9190: /*             else { */
                   9191: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   9192: /*             } */
                   9193: /*           } */
                   9194: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   9195: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   9196: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   9197: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   9198: /*           } */
                   9199: /*         } */
                   9200: /*         for(i=1; i<=nlstate;i++){ */
                   9201: /*           kk1=0.; */
                   9202: /*           for(j=1; j<=nlstate;j++){ */
                   9203: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   9204: /*           } */
                   9205: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   9206: /*         } */
1.218     brouard  9207:            
1.227     brouard  9208: /*         if (h==(int)(calagedatem+12*cpt)) */
                   9209: /*           for(j=1; j<=nlstate;j++)  */
                   9210: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   9211: /*       } */
                   9212: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9213: /*     } */
                   9214: /*       } */
1.218     brouard  9215:       
1.227     brouard  9216: /*       /\******\/ */
1.218     brouard  9217:       
1.227     brouard  9218: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   9219: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   9220: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   9221: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   9222: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  9223:          
1.227     brouard  9224: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9225: /*       oldm=oldms;savm=savms; */
                   9226: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9227: /*       for (h=0; h<=nhstepm; h++){ */
                   9228: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   9229: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   9230: /*         }  */
                   9231: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   9232: /*           kk1=0.;kk2=0; */
                   9233: /*           for(i=1; i<=nlstate;i++) {               */
                   9234: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   9235: /*           } */
                   9236: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   9237: /*         } */
                   9238: /*       } */
                   9239: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9240: /*     } */
                   9241: /*       } */
                   9242: /*     }  */
                   9243: /*   } */
1.218     brouard  9244:   
1.227     brouard  9245: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  9246:   
1.227     brouard  9247: /*   if (popforecast==1) { */
                   9248: /*     free_ivector(popage,0,AGESUP); */
                   9249: /*     free_vector(popeffectif,0,AGESUP); */
                   9250: /*     free_vector(popcount,0,AGESUP); */
                   9251: /*   } */
                   9252: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9253: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9254: /*   fclose(ficrespop); */
                   9255: /* } /\* End of popforecast *\/ */
1.218     brouard  9256:  
1.126     brouard  9257: int fileappend(FILE *fichier, char *optionfich)
                   9258: {
                   9259:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   9260:     printf("Problem with file: %s\n", optionfich);
                   9261:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   9262:     return (0);
                   9263:   }
                   9264:   fflush(fichier);
                   9265:   return (1);
                   9266: }
                   9267: 
                   9268: 
                   9269: /**************** function prwizard **********************/
                   9270: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   9271: {
                   9272: 
                   9273:   /* Wizard to print covariance matrix template */
                   9274: 
1.164     brouard  9275:   char ca[32], cb[32];
                   9276:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  9277:   int numlinepar;
                   9278: 
                   9279:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9280:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9281:   for(i=1; i <=nlstate; i++){
                   9282:     jj=0;
                   9283:     for(j=1; j <=nlstate+ndeath; j++){
                   9284:       if(j==i) continue;
                   9285:       jj++;
                   9286:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   9287:       printf("%1d%1d",i,j);
                   9288:       fprintf(ficparo,"%1d%1d",i,j);
                   9289:       for(k=1; k<=ncovmodel;k++){
                   9290:        /*        printf(" %lf",param[i][j][k]); */
                   9291:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   9292:        printf(" 0.");
                   9293:        fprintf(ficparo," 0.");
                   9294:       }
                   9295:       printf("\n");
                   9296:       fprintf(ficparo,"\n");
                   9297:     }
                   9298:   }
                   9299:   printf("# Scales (for hessian or gradient estimation)\n");
                   9300:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   9301:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   9302:   for(i=1; i <=nlstate; i++){
                   9303:     jj=0;
                   9304:     for(j=1; j <=nlstate+ndeath; j++){
                   9305:       if(j==i) continue;
                   9306:       jj++;
                   9307:       fprintf(ficparo,"%1d%1d",i,j);
                   9308:       printf("%1d%1d",i,j);
                   9309:       fflush(stdout);
                   9310:       for(k=1; k<=ncovmodel;k++){
                   9311:        /*      printf(" %le",delti3[i][j][k]); */
                   9312:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   9313:        printf(" 0.");
                   9314:        fprintf(ficparo," 0.");
                   9315:       }
                   9316:       numlinepar++;
                   9317:       printf("\n");
                   9318:       fprintf(ficparo,"\n");
                   9319:     }
                   9320:   }
                   9321:   printf("# Covariance matrix\n");
                   9322: /* # 121 Var(a12)\n\ */
                   9323: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9324: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   9325: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   9326: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   9327: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   9328: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   9329: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   9330:   fflush(stdout);
                   9331:   fprintf(ficparo,"# Covariance matrix\n");
                   9332:   /* # 121 Var(a12)\n\ */
                   9333:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9334:   /* #   ...\n\ */
                   9335:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   9336:   
                   9337:   for(itimes=1;itimes<=2;itimes++){
                   9338:     jj=0;
                   9339:     for(i=1; i <=nlstate; i++){
                   9340:       for(j=1; j <=nlstate+ndeath; j++){
                   9341:        if(j==i) continue;
                   9342:        for(k=1; k<=ncovmodel;k++){
                   9343:          jj++;
                   9344:          ca[0]= k+'a'-1;ca[1]='\0';
                   9345:          if(itimes==1){
                   9346:            printf("#%1d%1d%d",i,j,k);
                   9347:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   9348:          }else{
                   9349:            printf("%1d%1d%d",i,j,k);
                   9350:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   9351:            /*  printf(" %.5le",matcov[i][j]); */
                   9352:          }
                   9353:          ll=0;
                   9354:          for(li=1;li <=nlstate; li++){
                   9355:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   9356:              if(lj==li) continue;
                   9357:              for(lk=1;lk<=ncovmodel;lk++){
                   9358:                ll++;
                   9359:                if(ll<=jj){
                   9360:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   9361:                  if(ll<jj){
                   9362:                    if(itimes==1){
                   9363:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9364:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9365:                    }else{
                   9366:                      printf(" 0.");
                   9367:                      fprintf(ficparo," 0.");
                   9368:                    }
                   9369:                  }else{
                   9370:                    if(itimes==1){
                   9371:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   9372:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   9373:                    }else{
                   9374:                      printf(" 0.");
                   9375:                      fprintf(ficparo," 0.");
                   9376:                    }
                   9377:                  }
                   9378:                }
                   9379:              } /* end lk */
                   9380:            } /* end lj */
                   9381:          } /* end li */
                   9382:          printf("\n");
                   9383:          fprintf(ficparo,"\n");
                   9384:          numlinepar++;
                   9385:        } /* end k*/
                   9386:       } /*end j */
                   9387:     } /* end i */
                   9388:   } /* end itimes */
                   9389: 
                   9390: } /* end of prwizard */
                   9391: /******************* Gompertz Likelihood ******************************/
                   9392: double gompertz(double x[])
                   9393: { 
1.302     brouard  9394:   double A=0.0,B=0.,L=0.0,sump=0.,num=0.;
1.126     brouard  9395:   int i,n=0; /* n is the size of the sample */
                   9396: 
1.220     brouard  9397:   for (i=1;i<=imx ; i++) {
1.126     brouard  9398:     sump=sump+weight[i];
                   9399:     /*    sump=sump+1;*/
                   9400:     num=num+1;
                   9401:   }
1.302     brouard  9402:   L=0.0;
                   9403:   /* agegomp=AGEGOMP; */
1.126     brouard  9404:   /* for (i=0; i<=imx; i++) 
                   9405:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9406: 
1.302     brouard  9407:   for (i=1;i<=imx ; i++) {
                   9408:     /* mu(a)=mu(agecomp)*exp(teta*(age-agegomp))
                   9409:        mu(a)=x[1]*exp(x[2]*(age-agegomp)); x[1] and x[2] are per year.
                   9410:      * L= Product mu(agedeces)exp(-\int_ageexam^agedc mu(u) du ) for a death between agedc (in month) 
                   9411:      *   and agedc +1 month, cens[i]=0: log(x[1]/YEARM)
                   9412:      * +
                   9413:      * exp(-\int_ageexam^agecens mu(u) du ) when censored, cens[i]=1
                   9414:      */
                   9415:      if (wav[i] > 1 || agedc[i] < AGESUP) {
                   9416:        if (cens[i] == 1){
                   9417:         A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   9418:        } else if (cens[i] == 0){
1.126     brouard  9419:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
1.302     brouard  9420:          +log(x[1]/YEARM) +x[2]*(agedc[i]-agegomp)+log(YEARM);
                   9421:       } else
                   9422:         printf("Gompertz cens[%d] neither 1 nor 0\n",i);
1.126     brouard  9423:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
1.302     brouard  9424:        L=L+A*weight[i];
1.126     brouard  9425:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
1.302     brouard  9426:      }
                   9427:   }
1.126     brouard  9428: 
1.302     brouard  9429:   /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
1.126     brouard  9430:  
                   9431:   return -2*L*num/sump;
                   9432: }
                   9433: 
1.136     brouard  9434: #ifdef GSL
                   9435: /******************* Gompertz_f Likelihood ******************************/
                   9436: double gompertz_f(const gsl_vector *v, void *params)
                   9437: { 
1.302     brouard  9438:   double A=0.,B=0.,LL=0.0,sump=0.,num=0.;
1.136     brouard  9439:   double *x= (double *) v->data;
                   9440:   int i,n=0; /* n is the size of the sample */
                   9441: 
                   9442:   for (i=0;i<=imx-1 ; i++) {
                   9443:     sump=sump+weight[i];
                   9444:     /*    sump=sump+1;*/
                   9445:     num=num+1;
                   9446:   }
                   9447:  
                   9448:  
                   9449:   /* for (i=0; i<=imx; i++) 
                   9450:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9451:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9452:   for (i=1;i<=imx ; i++)
                   9453:     {
                   9454:       if (cens[i] == 1 && wav[i]>1)
                   9455:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9456:       
                   9457:       if (cens[i] == 0 && wav[i]>1)
                   9458:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9459:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9460:       
                   9461:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9462:       if (wav[i] > 1 ) { /* ??? */
                   9463:        LL=LL+A*weight[i];
                   9464:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9465:       }
                   9466:     }
                   9467: 
                   9468:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9469:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9470:  
                   9471:   return -2*LL*num/sump;
                   9472: }
                   9473: #endif
                   9474: 
1.126     brouard  9475: /******************* Printing html file ***********/
1.201     brouard  9476: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9477:                  int lastpass, int stepm, int weightopt, char model[],\
                   9478:                  int imx,  double p[],double **matcov,double agemortsup){
                   9479:   int i,k;
                   9480: 
                   9481:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9482:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9483:   for (i=1;i<=2;i++) 
                   9484:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9485:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9486:   fprintf(fichtm,"</ul>");
                   9487: 
                   9488: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9489: 
                   9490:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9491: 
                   9492:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9493:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9494: 
                   9495:  
                   9496:   fflush(fichtm);
                   9497: }
                   9498: 
                   9499: /******************* Gnuplot file **************/
1.201     brouard  9500: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9501: 
                   9502:   char dirfileres[132],optfileres[132];
1.164     brouard  9503: 
1.126     brouard  9504:   int ng;
                   9505: 
                   9506: 
                   9507:   /*#ifdef windows */
                   9508:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9509:     /*#endif */
                   9510: 
                   9511: 
                   9512:   strcpy(dirfileres,optionfilefiname);
                   9513:   strcpy(optfileres,"vpl");
1.199     brouard  9514:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9515:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9516:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9517:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9518:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9519: 
                   9520: } 
                   9521: 
1.136     brouard  9522: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9523: {
1.126     brouard  9524: 
1.136     brouard  9525:   /*-------- data file ----------*/
                   9526:   FILE *fic;
                   9527:   char dummy[]="                         ";
1.240     brouard  9528:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9529:   int lstra;
1.136     brouard  9530:   int linei, month, year,iout;
1.302     brouard  9531:   int noffset=0; /* This is the offset if BOM data file */
1.136     brouard  9532:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9533:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9534:   char *stratrunc;
1.223     brouard  9535: 
1.240     brouard  9536:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9537:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9538: 
1.240     brouard  9539:   for(v=1; v <=ncovcol;v++){
                   9540:     DummyV[v]=0;
                   9541:     FixedV[v]=0;
                   9542:   }
                   9543:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9544:     DummyV[v]=1;
                   9545:     FixedV[v]=0;
                   9546:   }
                   9547:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9548:     DummyV[v]=0;
                   9549:     FixedV[v]=1;
                   9550:   }
                   9551:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9552:     DummyV[v]=1;
                   9553:     FixedV[v]=1;
                   9554:   }
                   9555:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9556:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9557:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9558:   }
1.126     brouard  9559: 
1.136     brouard  9560:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9561:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9562:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9563:   }
1.126     brouard  9564: 
1.302     brouard  9565:     /* Is it a BOM UTF-8 Windows file? */
                   9566:   /* First data line */
                   9567:   linei=0;
                   9568:   while(fgets(line, MAXLINE, fic)) {
                   9569:     noffset=0;
                   9570:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   9571:     {
                   9572:       noffset=noffset+3;
                   9573:       printf("# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);fflush(stdout);
                   9574:       fprintf(ficlog,"# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);
                   9575:       fflush(ficlog); return 1;
                   9576:     }
                   9577:     /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   9578:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
                   9579:     {
                   9580:       noffset=noffset+2;
1.304     brouard  9581:       printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9582:       fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9583:       fflush(ficlog); return 1;
                   9584:     }
                   9585:     else if( line[0] == 0 && line[1] == 0)
                   9586:     {
                   9587:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   9588:        noffset=noffset+4;
1.304     brouard  9589:        printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9590:        fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9591:        fflush(ficlog); return 1;
                   9592:       }
                   9593:     } else{
                   9594:       ;/*printf(" Not a BOM file\n");*/
                   9595:     }
                   9596:         /* If line starts with a # it is a comment */
                   9597:     if (line[noffset] == '#') {
                   9598:       linei=linei+1;
                   9599:       break;
                   9600:     }else{
                   9601:       break;
                   9602:     }
                   9603:   }
                   9604:   fclose(fic);
                   9605:   if((fic=fopen(datafile,"r"))==NULL)    {
                   9606:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9607:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
                   9608:   }
                   9609:   /* Not a Bom file */
                   9610:   
1.136     brouard  9611:   i=1;
                   9612:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9613:     linei=linei+1;
                   9614:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9615:       if(line[j] == '\t')
                   9616:        line[j] = ' ';
                   9617:     }
                   9618:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9619:       ;
                   9620:     };
                   9621:     line[j+1]=0;  /* Trims blanks at end of line */
                   9622:     if(line[0]=='#'){
                   9623:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9624:       printf("Comment line\n%s\n",line);
                   9625:       continue;
                   9626:     }
                   9627:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9628:     strcpy(line, linetmp);
1.223     brouard  9629:     
                   9630:     /* Loops on waves */
                   9631:     for (j=maxwav;j>=1;j--){
                   9632:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9633:        cutv(stra, strb, line, ' '); 
                   9634:        if(strb[0]=='.') { /* Missing value */
                   9635:          lval=-1;
                   9636:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9637:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9638:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9639:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9640:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9641:            return 1;
                   9642:          }
                   9643:        }else{
                   9644:          errno=0;
                   9645:          /* what_kind_of_number(strb); */
                   9646:          dval=strtod(strb,&endptr); 
                   9647:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9648:          /* if(strb != endptr && *endptr == '\0') */
                   9649:          /*    dval=dlval; */
                   9650:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9651:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9652:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9653:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9654:            return 1;
                   9655:          }
                   9656:          cotqvar[j][iv][i]=dval; 
                   9657:          cotvar[j][ntv+iv][i]=dval; 
                   9658:        }
                   9659:        strcpy(line,stra);
1.223     brouard  9660:       }/* end loop ntqv */
1.225     brouard  9661:       
1.223     brouard  9662:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9663:        cutv(stra, strb, line, ' '); 
                   9664:        if(strb[0]=='.') { /* Missing value */
                   9665:          lval=-1;
                   9666:        }else{
                   9667:          errno=0;
                   9668:          lval=strtol(strb,&endptr,10); 
                   9669:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9670:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9671:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9672:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9673:            return 1;
                   9674:          }
                   9675:        }
                   9676:        if(lval <-1 || lval >1){
                   9677:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.319     brouard  9678:  Should be a value of %d(nth) covariate of wave %d (0 should be the value for the reference and 1\n \
1.223     brouard  9679:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9680:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9681:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9682:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9683:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9684:  output of IMaCh is often meaningless.\n                               \
1.319     brouard  9685:  Exiting.\n",lval,linei, i,line,iv,j);
1.238     brouard  9686:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.319     brouard  9687:  Should be a value of %d(nth) covariate of wave %d (0 should be the value for the reference and 1\n \
1.223     brouard  9688:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9689:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9690:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9691:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9692:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9693:  output of IMaCh is often meaningless.\n                               \
1.319     brouard  9694:  Exiting.\n",lval,linei, i,line,iv,j);fflush(ficlog);
1.238     brouard  9695:          return 1;
                   9696:        }
                   9697:        cotvar[j][iv][i]=(double)(lval);
                   9698:        strcpy(line,stra);
1.223     brouard  9699:       }/* end loop ntv */
1.225     brouard  9700:       
1.223     brouard  9701:       /* Statuses  at wave */
1.137     brouard  9702:       cutv(stra, strb, line, ' '); 
1.223     brouard  9703:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9704:        lval=-1;
1.136     brouard  9705:       }else{
1.238     brouard  9706:        errno=0;
                   9707:        lval=strtol(strb,&endptr,10); 
                   9708:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9709:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9710:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9711:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9712:          return 1;
                   9713:        }
1.136     brouard  9714:       }
1.225     brouard  9715:       
1.136     brouard  9716:       s[j][i]=lval;
1.225     brouard  9717:       
1.223     brouard  9718:       /* Date of Interview */
1.136     brouard  9719:       strcpy(line,stra);
                   9720:       cutv(stra, strb,line,' ');
1.169     brouard  9721:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9722:       }
1.169     brouard  9723:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9724:        month=99;
                   9725:        year=9999;
1.136     brouard  9726:       }else{
1.225     brouard  9727:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9728:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9729:        return 1;
1.136     brouard  9730:       }
                   9731:       anint[j][i]= (double) year; 
1.302     brouard  9732:       mint[j][i]= (double)month;
                   9733:       /* if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){ */
                   9734:       /*       printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9735:       /*       fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9736:       /* } */
1.136     brouard  9737:       strcpy(line,stra);
1.223     brouard  9738:     } /* End loop on waves */
1.225     brouard  9739:     
1.223     brouard  9740:     /* Date of death */
1.136     brouard  9741:     cutv(stra, strb,line,' '); 
1.169     brouard  9742:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9743:     }
1.169     brouard  9744:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9745:       month=99;
                   9746:       year=9999;
                   9747:     }else{
1.141     brouard  9748:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9749:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9750:       return 1;
1.136     brouard  9751:     }
                   9752:     andc[i]=(double) year; 
                   9753:     moisdc[i]=(double) month; 
                   9754:     strcpy(line,stra);
                   9755:     
1.223     brouard  9756:     /* Date of birth */
1.136     brouard  9757:     cutv(stra, strb,line,' '); 
1.169     brouard  9758:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9759:     }
1.169     brouard  9760:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9761:       month=99;
                   9762:       year=9999;
                   9763:     }else{
1.141     brouard  9764:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9765:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9766:       return 1;
1.136     brouard  9767:     }
                   9768:     if (year==9999) {
1.141     brouard  9769:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9770:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9771:       return 1;
                   9772:       
1.136     brouard  9773:     }
                   9774:     annais[i]=(double)(year);
1.302     brouard  9775:     moisnais[i]=(double)(month);
                   9776:     for (j=1;j<=maxwav;j++){
                   9777:       if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){
                   9778:        printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j,(int)moisnais[i],(int)annais[i]);
                   9779:        fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j, (int)moisnais[i],(int)annais[i]);
                   9780:       }
                   9781:     }
                   9782: 
1.136     brouard  9783:     strcpy(line,stra);
1.225     brouard  9784:     
1.223     brouard  9785:     /* Sample weight */
1.136     brouard  9786:     cutv(stra, strb,line,' '); 
                   9787:     errno=0;
                   9788:     dval=strtod(strb,&endptr); 
                   9789:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9790:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9791:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9792:       fflush(ficlog);
                   9793:       return 1;
                   9794:     }
                   9795:     weight[i]=dval; 
                   9796:     strcpy(line,stra);
1.225     brouard  9797:     
1.223     brouard  9798:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9799:       cutv(stra, strb, line, ' '); 
                   9800:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9801:        lval=-1;
1.311     brouard  9802:        coqvar[iv][i]=NAN; 
                   9803:        covar[ncovcol+iv][i]=NAN; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9804:       }else{
1.225     brouard  9805:        errno=0;
                   9806:        /* what_kind_of_number(strb); */
                   9807:        dval=strtod(strb,&endptr);
                   9808:        /* if(strb != endptr && *endptr == '\0') */
                   9809:        /*   dval=dlval; */
                   9810:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9811:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9812:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9813:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9814:          return 1;
                   9815:        }
                   9816:        coqvar[iv][i]=dval; 
1.226     brouard  9817:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9818:       }
                   9819:       strcpy(line,stra);
                   9820:     }/* end loop nqv */
1.136     brouard  9821:     
1.223     brouard  9822:     /* Covariate values */
1.136     brouard  9823:     for (j=ncovcol;j>=1;j--){
                   9824:       cutv(stra, strb,line,' '); 
1.223     brouard  9825:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9826:        lval=-1;
1.136     brouard  9827:       }else{
1.225     brouard  9828:        errno=0;
                   9829:        lval=strtol(strb,&endptr,10); 
                   9830:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9831:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9832:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9833:          return 1;
                   9834:        }
1.136     brouard  9835:       }
                   9836:       if(lval <-1 || lval >1){
1.225     brouard  9837:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9838:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9839:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9840:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9841:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9842:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9843:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9844:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9845:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9846:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9847:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9848:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9849:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9850:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9851:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9852:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9853:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9854:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9855:        return 1;
1.136     brouard  9856:       }
                   9857:       covar[j][i]=(double)(lval);
                   9858:       strcpy(line,stra);
                   9859:     }  
                   9860:     lstra=strlen(stra);
1.225     brouard  9861:     
1.136     brouard  9862:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9863:       stratrunc = &(stra[lstra-9]);
                   9864:       num[i]=atol(stratrunc);
                   9865:     }
                   9866:     else
                   9867:       num[i]=atol(stra);
                   9868:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9869:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9870:     
                   9871:     i=i+1;
                   9872:   } /* End loop reading  data */
1.225     brouard  9873:   
1.136     brouard  9874:   *imax=i-1; /* Number of individuals */
                   9875:   fclose(fic);
1.225     brouard  9876:   
1.136     brouard  9877:   return (0);
1.164     brouard  9878:   /* endread: */
1.225     brouard  9879:   printf("Exiting readdata: ");
                   9880:   fclose(fic);
                   9881:   return (1);
1.223     brouard  9882: }
1.126     brouard  9883: 
1.234     brouard  9884: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9885:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9886:   while (*p2 == ' ')
1.234     brouard  9887:     p2++; 
                   9888:   /* while ((*p1++ = *p2++) !=0) */
                   9889:   /*   ; */
                   9890:   /* do */
                   9891:   /*   while (*p2 == ' ') */
                   9892:   /*     p2++; */
                   9893:   /* while (*p1++ == *p2++); */
                   9894:   *stri=p2; 
1.145     brouard  9895: }
                   9896: 
1.235     brouard  9897: int decoderesult ( char resultline[], int nres)
1.230     brouard  9898: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9899: {
1.235     brouard  9900:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9901:   char resultsav[MAXLINE];
1.234     brouard  9902:   int resultmodel[MAXLINE];
                   9903:   int modelresult[MAXLINE];
1.230     brouard  9904:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9905: 
1.234     brouard  9906:   removefirstspace(&resultline);
1.230     brouard  9907: 
                   9908:   if (strstr(resultline,"v") !=0){
                   9909:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9910:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9911:     return 1;
                   9912:   }
                   9913:   trimbb(resultsav, resultline);
                   9914:   if (strlen(resultsav) >1){
                   9915:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9916:   }
1.253     brouard  9917:   if(j == 0){ /* Resultline but no = */
                   9918:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9919:     return (0);
                   9920:   }
1.234     brouard  9921:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
1.318     brouard  9922:     printf("ERROR: the number of variables in this result line, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
1.310     brouard  9923:     fprintf(ficlog,"ERROR: the number of variables in the resultline, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
1.234     brouard  9924:   }
                   9925:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9926:     if(nbocc(resultsav,'=') >1){
1.318     brouard  9927:       cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' (stra is the rest of the resultline to be analyzed in the next loop *//*     resultsav= "V4=1 V5=25.1 V3=0" stra= "V5=25.1 V3=0" strb= "V4=1" */
                   9928:       cutl(strc,strd,strb,'=');  /* strb:"V4=1" strc="1" strd="V4" */
1.234     brouard  9929:     }else
                   9930:       cutl(strc,strd,resultsav,'=');
1.318     brouard  9931:     Tvalsel[k]=atof(strc); /* 1 */ /* Tvalsel of k is the float value of the kth covariate appearing in this result line */
1.234     brouard  9932:     
1.230     brouard  9933:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
1.318     brouard  9934:     Tvarsel[k]=atoi(strc);  /* 4 */ /* Tvarsel is the id of the kth covariate in the result line Tvarsel[1] in "V4=1.." is 4.*/
1.230     brouard  9935:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9936:     /* cptcovsel++;     */
                   9937:     if (nbocc(stra,'=') >0)
                   9938:       strcpy(resultsav,stra); /* and analyzes it */
                   9939:   }
1.235     brouard  9940:   /* Checking for missing or useless values in comparison of current model needs */
1.318     brouard  9941:   for(k1=1; k1<= cptcovt ;k1++){ /* Loop on model. model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9942:     if(Typevar[k1]==0){ /* Single covariate in model *//*0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.234     brouard  9943:       match=0;
1.318     brouard  9944:       for(k2=1; k2 <=j;k2++){/* Loop on resultline. In result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9945:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar is coming from the model, Tvarsel from the result. Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9946:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.318     brouard  9947:          match=1; /* modelresult of k2 variable of resultline is identical to k1 variable of the model good */
1.234     brouard  9948:          break;
                   9949:        }
                   9950:       }
                   9951:       if(match == 0){
1.310     brouard  9952:        printf("Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9953:        fprintf(ficlog,"Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9954:        return 1;
1.234     brouard  9955:       }
                   9956:     }
                   9957:   }
1.235     brouard  9958:   /* Checking for missing or useless values in comparison of current model needs */
1.318     brouard  9959:   for(k2=1; k2 <=j;k2++){ /* Loop on resultline variables: result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9960:     match=0;
1.318     brouard  9961:     for(k1=1; k1<= cptcovt ;k1++){ /* loop on model: model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.235     brouard  9962:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9963:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.318     brouard  9964:          resultmodel[k1]=k2;  /* k2th variable of the model corresponds to k1 variable of the model. resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9965:          ++match;
                   9966:        }
                   9967:       }
                   9968:     }
                   9969:     if(match == 0){
                   9970:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
1.310     brouard  9971:       fprintf(ficlog,"Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9972:       return 1;
1.234     brouard  9973:     }else if(match > 1){
                   9974:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
1.310     brouard  9975:       fprintf(ficlog,"Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9976:       return 1;
1.234     brouard  9977:     }
                   9978:   }
1.235     brouard  9979:       
1.234     brouard  9980:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9981:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9982:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9983:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9984:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9985:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9986:   /*    1 0 0 0 */
                   9987:   /*    2 1 0 0 */
                   9988:   /*    3 0 1 0 */ 
                   9989:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9990:   /*    5 0 0 1 */
                   9991:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9992:   /*    7 0 1 1 */
                   9993:   /*    8 1 1 1 */
1.237     brouard  9994:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9995:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9996:   /* V5*age V5 known which value for nres?  */
                   9997:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.318     brouard  9998:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* loop on model line */
1.235     brouard  9999:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  10000:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  10001:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   10002:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  10003:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   10004:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   10005:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  10006:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   10007:       k4++;;
                   10008:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
1.318     brouard  10009:       k3q= resultmodel[k1]; /* resultmodel[1(V5)] = 25.1=k3q */
                   10010:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[1]]= Tvarsel[1] = 4=k2 */
1.237     brouard  10011:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   10012:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   10013:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  10014:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   10015:       k4q++;;
                   10016:     }
                   10017:   }
1.234     brouard  10018:   
1.235     brouard  10019:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  10020:   return (0);
                   10021: }
1.235     brouard  10022: 
1.230     brouard  10023: int decodemodel( char model[], int lastobs)
                   10024:  /**< This routine decodes the model and returns:
1.224     brouard  10025:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   10026:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   10027:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   10028:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   10029:        * - cptcovage number of covariates with age*products =2
                   10030:        * - cptcovs number of simple covariates
                   10031:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   10032:        *     which is a new column after the 9 (ncovcol) variables. 
1.319     brouard  10033:        * - if k is a product Vn*Vm, covar[k][i] is filled with correct values for each individual
1.224     brouard  10034:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   10035:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   10036:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   10037:        */
1.319     brouard  10038: /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1, Tage[1]=2 */
1.136     brouard  10039: {
1.238     brouard  10040:   int i, j, k, ks, v;
1.227     brouard  10041:   int  j1, k1, k2, k3, k4;
1.136     brouard  10042:   char modelsav[80];
1.145     brouard  10043:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  10044:   char *strpt;
1.136     brouard  10045: 
1.145     brouard  10046:   /*removespace(model);*/
1.136     brouard  10047:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  10048:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  10049:     if (strstr(model,"AGE") !=0){
1.192     brouard  10050:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   10051:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  10052:       return 1;
                   10053:     }
1.141     brouard  10054:     if (strstr(model,"v") !=0){
                   10055:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   10056:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   10057:       return 1;
                   10058:     }
1.187     brouard  10059:     strcpy(modelsav,model); 
                   10060:     if ((strpt=strstr(model,"age*age")) !=0){
                   10061:       printf(" strpt=%s, model=%s\n",strpt, model);
                   10062:       if(strpt != model){
1.234     brouard  10063:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  10064:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  10065:  corresponding column of parameters.\n",model);
1.234     brouard  10066:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  10067:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  10068:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  10069:        return 1;
1.225     brouard  10070:       }
1.187     brouard  10071:       nagesqr=1;
                   10072:       if (strstr(model,"+age*age") !=0)
1.234     brouard  10073:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  10074:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  10075:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  10076:       else 
1.234     brouard  10077:        substrchaine(modelsav, model, "age*age");
1.187     brouard  10078:     }else
                   10079:       nagesqr=0;
                   10080:     if (strlen(modelsav) >1){
                   10081:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   10082:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  10083:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  10084:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  10085:                     * cst, age and age*age 
                   10086:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   10087:       /* including age products which are counted in cptcovage.
                   10088:        * but the covariates which are products must be treated 
                   10089:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  10090:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   10091:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  10092:       
                   10093:       
1.187     brouard  10094:       /*   Design
                   10095:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   10096:        *  <          ncovcol=8                >
                   10097:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   10098:        *   k=  1    2      3       4     5       6      7        8
                   10099:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   10100:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  10101:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   10102:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  10103:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   10104:        *  Tage[++cptcovage]=k
                   10105:        *       if products, new covar are created after ncovcol with k1
                   10106:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   10107:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   10108:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   10109:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   10110:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   10111:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   10112:        *  <          ncovcol=8                >
                   10113:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   10114:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   10115:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
1.319     brouard  10116:        * p Tvar[1]@12={2,   1,     3,      3,  11,     10,     8,       8,   7,   8,   5,  6}
1.187     brouard  10117:        * p Tprod[1]@2={                         6, 5}
                   10118:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   10119:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   10120:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
1.319     brouard  10121:        *How to reorganize? Tvars(orted)
1.187     brouard  10122:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   10123:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   10124:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   10125:        * Struct []
                   10126:        */
1.225     brouard  10127:       
1.187     brouard  10128:       /* This loop fills the array Tvar from the string 'model'.*/
                   10129:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   10130:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   10131:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   10132:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   10133:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   10134:       /*       k=1 Tvar[1]=2 (from V2) */
                   10135:       /*       k=5 Tvar[5] */
                   10136:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  10137:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  10138:       /*       } */
1.198     brouard  10139:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  10140:       /*
                   10141:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  10142:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   10143:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   10144:       }
1.187     brouard  10145:       cptcovage=0;
1.319     brouard  10146:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model line */
                   10147:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' cutl from left to right
                   10148:                                         modelsav==V2+V1+V5*age+V4+V3*age strb=V3*age stra=V2+V1V5*age+V4 */    /* <model> "V5+V4+V3+V4*V3+V5*age+V1*age+V1" strb="V5" stra="V4+V3+V4*V3+V5*age+V1*age+V1" */
                   10149:        if (nbocc(modelsav,'+')==0)
                   10150:          strcpy(strb,modelsav); /* and analyzes it */
1.234     brouard  10151:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   10152:        /*scanf("%d",i);*/
1.319     brouard  10153:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V5*age+ V4+V3*age strb=V3*age */
                   10154:          cutl(strc,strd,strb,'*'); /**< k=1 strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
1.234     brouard  10155:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   10156:            /* covar is not filled and then is empty */
                   10157:            cptcovprod--;
                   10158:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
1.319     brouard  10159:            Tvar[k]=atoi(stre);  /* V2+V1+V5*age+V4+V3*age Tvar[5]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
1.234     brouard  10160:            Typevar[k]=1;  /* 1 for age product */
1.319     brouard  10161:            cptcovage++; /* Counts the number of covariates which include age as a product */
                   10162:            Tage[cptcovage]=k;  /*  V2+V1+V4+V3*age Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
1.234     brouard  10163:            /*printf("stre=%s ", stre);*/
                   10164:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   10165:            cptcovprod--;
                   10166:            cutl(stre,strb,strc,'V');
                   10167:            Tvar[k]=atoi(stre);
                   10168:            Typevar[k]=1;  /* 1 for age product */
                   10169:            cptcovage++;
                   10170:            Tage[cptcovage]=k;
                   10171:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   10172:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   10173:            cptcovn++;
                   10174:            cptcovprodnoage++;k1++;
                   10175:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   10176:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   10177:                                                because this model-covariate is a construction we invent a new column
                   10178:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
1.319     brouard  10179:                                                If already ncovcol=4 and model=V2 + V1 +V1*V4 +age*V3 +V3*V2
                   10180:                                                thus after V4 we invent V5 and V6 because age*V3 will be computed in 4
                   10181:                                                Tvar[3=V1*V4]=4+1=5 Tvar[5=V3*V2]=4 + 2= 6, Tvar[4=age*V3]=4 etc */
1.234     brouard  10182:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   10183:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   10184:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
1.319     brouard  10185:            Tposprod[k]=k1; /* Tposprod[3]=1, Tposprod[2]=5 */
1.234     brouard  10186:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   10187:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   10188:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   10189:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   10190:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  10191:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  10192:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   10193:            for (i=1; i<=lastobs;i++){
                   10194:              /* Computes the new covariate which is a product of
                   10195:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   10196:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   10197:            }
                   10198:          } /* End age is not in the model */
                   10199:        } /* End if model includes a product */
1.319     brouard  10200:        else { /* not a product */
1.234     brouard  10201:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   10202:          /*  scanf("%d",i);*/
                   10203:          cutl(strd,strc,strb,'V');
                   10204:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   10205:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   10206:          Tvar[k]=atoi(strd);
                   10207:          Typevar[k]=0;  /* 0 for simple covariates */
                   10208:        }
                   10209:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  10210:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  10211:                                  scanf("%d",i);*/
1.187     brouard  10212:       } /* end of loop + on total covariates */
                   10213:     } /* end if strlen(modelsave == 0) age*age might exist */
                   10214:   } /* end if strlen(model == 0) */
1.136     brouard  10215:   
                   10216:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   10217:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  10218:   
1.136     brouard  10219:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  10220:      printf("cptcovprod=%d ", cptcovprod);
                   10221:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   10222:      scanf("%d ",i);*/
                   10223: 
                   10224: 
1.230     brouard  10225: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   10226:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  10227: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   10228:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   10229:    k =           1    2   3     4       5       6      7      8        9
                   10230:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
1.319     brouard  10231:    Typevar[k]=   0    0   0     2       1       0      2      1        0
1.227     brouard  10232:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   10233:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   10234:          Tmodelind[combination of covar]=k;
1.225     brouard  10235: */  
                   10236: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  10237:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  10238:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  10239:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.318     brouard  10240:   printf("Model=1+age+%s\n\
1.227     brouard  10241: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   10242: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   10243: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.318     brouard  10244:   fprintf(ficlog,"Model=1+age+%s\n\
1.227     brouard  10245: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   10246: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   10247: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  10248:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  10249:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   10250:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  10251:       Fixed[k]= 0;
                   10252:       Dummy[k]= 0;
1.225     brouard  10253:       ncoveff++;
1.232     brouard  10254:       ncovf++;
1.234     brouard  10255:       nsd++;
                   10256:       modell[k].maintype= FTYPE;
                   10257:       TvarsD[nsd]=Tvar[k];
                   10258:       TvarsDind[nsd]=k;
                   10259:       TvarF[ncovf]=Tvar[k];
                   10260:       TvarFind[ncovf]=k;
                   10261:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10262:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10263:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   10264:       Fixed[k]= 0;
                   10265:       Dummy[k]= 0;
                   10266:       ncoveff++;
                   10267:       ncovf++;
                   10268:       modell[k].maintype= FTYPE;
                   10269:       TvarF[ncovf]=Tvar[k];
                   10270:       TvarFind[ncovf]=k;
1.230     brouard  10271:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  10272:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  10273:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  10274:       Fixed[k]= 0;
                   10275:       Dummy[k]= 1;
1.230     brouard  10276:       nqfveff++;
1.234     brouard  10277:       modell[k].maintype= FTYPE;
                   10278:       modell[k].subtype= FQ;
                   10279:       nsq++;
                   10280:       TvarsQ[nsq]=Tvar[k];
                   10281:       TvarsQind[nsq]=k;
1.232     brouard  10282:       ncovf++;
1.234     brouard  10283:       TvarF[ncovf]=Tvar[k];
                   10284:       TvarFind[ncovf]=k;
1.231     brouard  10285:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  10286:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  10287:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  10288:       Fixed[k]= 1;
                   10289:       Dummy[k]= 0;
1.225     brouard  10290:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  10291:       modell[k].maintype= VTYPE;
                   10292:       modell[k].subtype= VD;
                   10293:       nsd++;
                   10294:       TvarsD[nsd]=Tvar[k];
                   10295:       TvarsDind[nsd]=k;
                   10296:       ncovv++; /* Only simple time varying variables */
                   10297:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10298:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10299:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   10300:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  10301:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   10302:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  10303:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  10304:       Fixed[k]= 1;
                   10305:       Dummy[k]= 1;
                   10306:       nqtveff++;
                   10307:       modell[k].maintype= VTYPE;
                   10308:       modell[k].subtype= VQ;
                   10309:       ncovv++; /* Only simple time varying variables */
                   10310:       nsq++;
1.319     brouard  10311:       TvarsQ[nsq]=Tvar[k]; /* k=1 Tvar=5 nsq=1 TvarsQ[1]=5 */
1.234     brouard  10312:       TvarsQind[nsq]=k;
                   10313:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10314:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10315:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   10316:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  10317:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   10318:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   10319:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  10320:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  10321:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  10322:       ncova++;
                   10323:       TvarA[ncova]=Tvar[k];
                   10324:       TvarAind[ncova]=k;
1.231     brouard  10325:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  10326:        Fixed[k]= 2;
                   10327:        Dummy[k]= 2;
                   10328:        modell[k].maintype= ATYPE;
                   10329:        modell[k].subtype= APFD;
                   10330:        /* ncoveff++; */
1.227     brouard  10331:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  10332:        Fixed[k]= 2;
                   10333:        Dummy[k]= 3;
                   10334:        modell[k].maintype= ATYPE;
                   10335:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   10336:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  10337:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  10338:        Fixed[k]= 3;
                   10339:        Dummy[k]= 2;
                   10340:        modell[k].maintype= ATYPE;
                   10341:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   10342:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  10343:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10344:        Fixed[k]= 3;
                   10345:        Dummy[k]= 3;
                   10346:        modell[k].maintype= ATYPE;
                   10347:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   10348:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  10349:       }
                   10350:     }else if (Typevar[k] == 2) {  /* product without age */
                   10351:       k1=Tposprod[k];
                   10352:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  10353:        if(Tvard[k1][2] <=ncovcol){
                   10354:          Fixed[k]= 1;
                   10355:          Dummy[k]= 0;
                   10356:          modell[k].maintype= FTYPE;
                   10357:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   10358:          ncovf++; /* Fixed variables without age */
                   10359:          TvarF[ncovf]=Tvar[k];
                   10360:          TvarFind[ncovf]=k;
                   10361:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10362:          Fixed[k]= 0;  /* or 2 ?*/
                   10363:          Dummy[k]= 1;
                   10364:          modell[k].maintype= FTYPE;
                   10365:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   10366:          ncovf++; /* Varying variables without age */
                   10367:          TvarF[ncovf]=Tvar[k];
                   10368:          TvarFind[ncovf]=k;
                   10369:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10370:          Fixed[k]= 1;
                   10371:          Dummy[k]= 0;
                   10372:          modell[k].maintype= VTYPE;
                   10373:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   10374:          ncovv++; /* Varying variables without age */
                   10375:          TvarV[ncovv]=Tvar[k];
                   10376:          TvarVind[ncovv]=k;
                   10377:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10378:          Fixed[k]= 1;
                   10379:          Dummy[k]= 1;
                   10380:          modell[k].maintype= VTYPE;
                   10381:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   10382:          ncovv++; /* Varying variables without age */
                   10383:          TvarV[ncovv]=Tvar[k];
                   10384:          TvarVind[ncovv]=k;
                   10385:        }
1.227     brouard  10386:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  10387:        if(Tvard[k1][2] <=ncovcol){
                   10388:          Fixed[k]= 0;  /* or 2 ?*/
                   10389:          Dummy[k]= 1;
                   10390:          modell[k].maintype= FTYPE;
                   10391:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   10392:          ncovf++; /* Fixed variables without age */
                   10393:          TvarF[ncovf]=Tvar[k];
                   10394:          TvarFind[ncovf]=k;
                   10395:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10396:          Fixed[k]= 1;
                   10397:          Dummy[k]= 1;
                   10398:          modell[k].maintype= VTYPE;
                   10399:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   10400:          ncovv++; /* Varying variables without age */
                   10401:          TvarV[ncovv]=Tvar[k];
                   10402:          TvarVind[ncovv]=k;
                   10403:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10404:          Fixed[k]= 1;
                   10405:          Dummy[k]= 1;
                   10406:          modell[k].maintype= VTYPE;
                   10407:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   10408:          ncovv++; /* Varying variables without age */
                   10409:          TvarV[ncovv]=Tvar[k];
                   10410:          TvarVind[ncovv]=k;
                   10411:          ncovv++; /* Varying variables without age */
                   10412:          TvarV[ncovv]=Tvar[k];
                   10413:          TvarVind[ncovv]=k;
                   10414:        }
1.227     brouard  10415:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  10416:        if(Tvard[k1][2] <=ncovcol){
                   10417:          Fixed[k]= 1;
                   10418:          Dummy[k]= 1;
                   10419:          modell[k].maintype= VTYPE;
                   10420:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   10421:          ncovv++; /* Varying variables without age */
                   10422:          TvarV[ncovv]=Tvar[k];
                   10423:          TvarVind[ncovv]=k;
                   10424:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10425:          Fixed[k]= 1;
                   10426:          Dummy[k]= 1;
                   10427:          modell[k].maintype= VTYPE;
                   10428:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   10429:          ncovv++; /* Varying variables without age */
                   10430:          TvarV[ncovv]=Tvar[k];
                   10431:          TvarVind[ncovv]=k;
                   10432:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10433:          Fixed[k]= 1;
                   10434:          Dummy[k]= 0;
                   10435:          modell[k].maintype= VTYPE;
                   10436:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   10437:          ncovv++; /* Varying variables without age */
                   10438:          TvarV[ncovv]=Tvar[k];
                   10439:          TvarVind[ncovv]=k;
                   10440:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10441:          Fixed[k]= 1;
                   10442:          Dummy[k]= 1;
                   10443:          modell[k].maintype= VTYPE;
                   10444:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   10445:          ncovv++; /* Varying variables without age */
                   10446:          TvarV[ncovv]=Tvar[k];
                   10447:          TvarVind[ncovv]=k;
                   10448:        }
1.227     brouard  10449:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10450:        if(Tvard[k1][2] <=ncovcol){
                   10451:          Fixed[k]= 1;
                   10452:          Dummy[k]= 1;
                   10453:          modell[k].maintype= VTYPE;
                   10454:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   10455:          ncovv++; /* Varying variables without age */
                   10456:          TvarV[ncovv]=Tvar[k];
                   10457:          TvarVind[ncovv]=k;
                   10458:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10459:          Fixed[k]= 1;
                   10460:          Dummy[k]= 1;
                   10461:          modell[k].maintype= VTYPE;
                   10462:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   10463:          ncovv++; /* Varying variables without age */
                   10464:          TvarV[ncovv]=Tvar[k];
                   10465:          TvarVind[ncovv]=k;
                   10466:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10467:          Fixed[k]= 1;
                   10468:          Dummy[k]= 1;
                   10469:          modell[k].maintype= VTYPE;
                   10470:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   10471:          ncovv++; /* Varying variables without age */
                   10472:          TvarV[ncovv]=Tvar[k];
                   10473:          TvarVind[ncovv]=k;
                   10474:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10475:          Fixed[k]= 1;
                   10476:          Dummy[k]= 1;
                   10477:          modell[k].maintype= VTYPE;
                   10478:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10479:          ncovv++; /* Varying variables without age */
                   10480:          TvarV[ncovv]=Tvar[k];
                   10481:          TvarVind[ncovv]=k;
                   10482:        }
1.227     brouard  10483:       }else{
1.240     brouard  10484:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10485:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10486:       } /*end k1*/
1.225     brouard  10487:     }else{
1.226     brouard  10488:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10489:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10490:     }
1.227     brouard  10491:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10492:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10493:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10494:   }
                   10495:   /* Searching for doublons in the model */
                   10496:   for(k1=1; k1<= cptcovt;k1++){
                   10497:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10498:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10499:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10500:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10501:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10502:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10503:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10504:            return(1);
                   10505:          }
                   10506:        }else if (Typevar[k1] ==2){
                   10507:          k3=Tposprod[k1];
                   10508:          k4=Tposprod[k2];
                   10509:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10510:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10511:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10512:            return(1);
                   10513:          }
                   10514:        }
1.227     brouard  10515:       }
                   10516:     }
1.225     brouard  10517:   }
                   10518:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10519:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10520:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10521:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10522:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10523:   /*endread:*/
1.225     brouard  10524:   printf("Exiting decodemodel: ");
                   10525:   return (1);
1.136     brouard  10526: }
                   10527: 
1.169     brouard  10528: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10529: {/* Check ages at death */
1.136     brouard  10530:   int i, m;
1.218     brouard  10531:   int firstone=0;
                   10532:   
1.136     brouard  10533:   for (i=1; i<=imx; i++) {
                   10534:     for(m=2; (m<= maxwav); m++) {
                   10535:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10536:        anint[m][i]=9999;
1.216     brouard  10537:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10538:          s[m][i]=-1;
1.136     brouard  10539:       }
                   10540:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10541:        *nberr = *nberr + 1;
1.218     brouard  10542:        if(firstone == 0){
                   10543:          firstone=1;
1.260     brouard  10544:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10545:        }
1.262     brouard  10546:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10547:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10548:       }
                   10549:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10550:        (*nberr)++;
1.259     brouard  10551:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10552:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10553:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10554:       }
                   10555:     }
                   10556:   }
                   10557: 
                   10558:   for (i=1; i<=imx; i++)  {
                   10559:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10560:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10561:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10562:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10563:          if(agedc[i]>0){
                   10564:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10565:              agev[m][i]=agedc[i];
1.214     brouard  10566:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10567:            }else {
1.136     brouard  10568:              if ((int)andc[i]!=9999){
                   10569:                nbwarn++;
                   10570:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10571:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10572:                agev[m][i]=-1;
                   10573:              }
                   10574:            }
1.169     brouard  10575:          } /* agedc > 0 */
1.214     brouard  10576:        } /* end if */
1.136     brouard  10577:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10578:                                 years but with the precision of a month */
                   10579:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10580:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10581:            agev[m][i]=1;
                   10582:          else if(agev[m][i] < *agemin){ 
                   10583:            *agemin=agev[m][i];
                   10584:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10585:          }
                   10586:          else if(agev[m][i] >*agemax){
                   10587:            *agemax=agev[m][i];
1.156     brouard  10588:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10589:          }
                   10590:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10591:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10592:        } /* en if 9*/
1.136     brouard  10593:        else { /* =9 */
1.214     brouard  10594:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10595:          agev[m][i]=1;
                   10596:          s[m][i]=-1;
                   10597:        }
                   10598:       }
1.214     brouard  10599:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10600:        agev[m][i]=1;
1.214     brouard  10601:       else{
                   10602:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10603:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10604:        agev[m][i]=0;
                   10605:       }
                   10606:     } /* End for lastpass */
                   10607:   }
1.136     brouard  10608:     
                   10609:   for (i=1; i<=imx; i++)  {
                   10610:     for(m=firstpass; (m<=lastpass); m++){
                   10611:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10612:        (*nberr)++;
1.136     brouard  10613:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10614:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10615:        return 1;
                   10616:       }
                   10617:     }
                   10618:   }
                   10619: 
                   10620:   /*for (i=1; i<=imx; i++){
                   10621:   for (m=firstpass; (m<lastpass); m++){
                   10622:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10623: }
                   10624: 
                   10625: }*/
                   10626: 
                   10627: 
1.139     brouard  10628:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10629:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10630: 
                   10631:   return (0);
1.164     brouard  10632:  /* endread:*/
1.136     brouard  10633:     printf("Exiting calandcheckages: ");
                   10634:     return (1);
                   10635: }
                   10636: 
1.172     brouard  10637: #if defined(_MSC_VER)
                   10638: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10639: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10640: //#include "stdafx.h"
                   10641: //#include <stdio.h>
                   10642: //#include <tchar.h>
                   10643: //#include <windows.h>
                   10644: //#include <iostream>
                   10645: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10646: 
                   10647: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10648: 
                   10649: BOOL IsWow64()
                   10650: {
                   10651:        BOOL bIsWow64 = FALSE;
                   10652: 
                   10653:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10654:        //  (HANDLE, PBOOL);
                   10655: 
                   10656:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10657: 
                   10658:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10659:        const char funcName[] = "IsWow64Process";
                   10660:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10661:                GetProcAddress(module, funcName);
                   10662: 
                   10663:        if (NULL != fnIsWow64Process)
                   10664:        {
                   10665:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10666:                        &bIsWow64))
                   10667:                        //throw std::exception("Unknown error");
                   10668:                        printf("Unknown error\n");
                   10669:        }
                   10670:        return bIsWow64 != FALSE;
                   10671: }
                   10672: #endif
1.177     brouard  10673: 
1.191     brouard  10674: void syscompilerinfo(int logged)
1.292     brouard  10675: {
                   10676: #include <stdint.h>
                   10677: 
                   10678:   /* #include "syscompilerinfo.h"*/
1.185     brouard  10679:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10680:    /* /GS /W3 /Gy
                   10681:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10682:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10683:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10684:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10685:    */ 
                   10686:    /* 64 bits */
1.185     brouard  10687:    /*
                   10688:      /GS /W3 /Gy
                   10689:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10690:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10691:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10692:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10693:    /* Optimization are useless and O3 is slower than O2 */
                   10694:    /*
                   10695:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10696:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10697:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10698:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10699:    */
1.186     brouard  10700:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10701:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10702:       /PDB:"visual studio
                   10703:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10704:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10705:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10706:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10707:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10708:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10709:       uiAccess='false'"
                   10710:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10711:       /NOLOGO /TLBID:1
                   10712:    */
1.292     brouard  10713: 
                   10714: 
1.177     brouard  10715: #if defined __INTEL_COMPILER
1.178     brouard  10716: #if defined(__GNUC__)
                   10717:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10718: #endif
1.177     brouard  10719: #elif defined(__GNUC__) 
1.179     brouard  10720: #ifndef  __APPLE__
1.174     brouard  10721: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10722: #endif
1.177     brouard  10723:    struct utsname sysInfo;
1.178     brouard  10724:    int cross = CROSS;
                   10725:    if (cross){
                   10726:           printf("Cross-");
1.191     brouard  10727:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10728:    }
1.174     brouard  10729: #endif
                   10730: 
1.191     brouard  10731:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10732: #if defined(__clang__)
1.191     brouard  10733:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10734: #endif
                   10735: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10736:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10737: #endif
                   10738: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10739:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10740: #endif
                   10741: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10742:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10743: #endif
                   10744: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10745:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10746: #endif
                   10747: #if defined(_MSC_VER)
1.191     brouard  10748:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10749: #endif
                   10750: #if defined(__PGI)
1.191     brouard  10751:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10752: #endif
                   10753: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10754:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10755: #endif
1.191     brouard  10756:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10757:    
1.167     brouard  10758: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10759: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10760:     // Windows (x64 and x86)
1.191     brouard  10761:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10762: #elif __unix__ // all unices, not all compilers
                   10763:     // Unix
1.191     brouard  10764:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10765: #elif __linux__
                   10766:     // linux
1.191     brouard  10767:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10768: #elif __APPLE__
1.174     brouard  10769:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10770:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10771: #endif
                   10772: 
                   10773: /*  __MINGW32__          */
                   10774: /*  __CYGWIN__  */
                   10775: /* __MINGW64__  */
                   10776: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10777: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10778: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10779: /* _WIN64  // Defined for applications for Win64. */
                   10780: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10781: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10782: 
1.167     brouard  10783: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10784:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10785: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10786:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10787: #else
1.191     brouard  10788:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10789: #endif
                   10790: 
1.169     brouard  10791: #if defined(__GNUC__)
                   10792: # if defined(__GNUC_PATCHLEVEL__)
                   10793: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10794:                             + __GNUC_MINOR__ * 100 \
                   10795:                             + __GNUC_PATCHLEVEL__)
                   10796: # else
                   10797: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10798:                             + __GNUC_MINOR__ * 100)
                   10799: # endif
1.174     brouard  10800:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10801:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10802: 
                   10803:    if (uname(&sysInfo) != -1) {
                   10804:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10805:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10806:    }
                   10807:    else
                   10808:       perror("uname() error");
1.179     brouard  10809:    //#ifndef __INTEL_COMPILER 
                   10810: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10811:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10812:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10813: #endif
1.169     brouard  10814: #endif
1.172     brouard  10815: 
1.286     brouard  10816:    //   void main ()
1.172     brouard  10817:    //   {
1.169     brouard  10818: #if defined(_MSC_VER)
1.174     brouard  10819:    if (IsWow64()){
1.191     brouard  10820:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10821:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10822:    }
                   10823:    else{
1.191     brouard  10824:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10825:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10826:    }
1.172     brouard  10827:    //     printf("\nPress Enter to continue...");
                   10828:    //     getchar();
                   10829:    //   }
                   10830: 
1.169     brouard  10831: #endif
                   10832:    
1.167     brouard  10833: 
1.219     brouard  10834: }
1.136     brouard  10835: 
1.219     brouard  10836: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10837:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10838:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10839:   /* double ftolpl = 1.e-10; */
1.180     brouard  10840:   double age, agebase, agelim;
1.203     brouard  10841:   double tot;
1.180     brouard  10842: 
1.202     brouard  10843:   strcpy(filerespl,"PL_");
                   10844:   strcat(filerespl,fileresu);
                   10845:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10846:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10847:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10848:   }
1.288     brouard  10849:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10850:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10851:   pstamp(ficrespl);
1.288     brouard  10852:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10853:   fprintf(ficrespl,"#Age ");
                   10854:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10855:   fprintf(ficrespl,"\n");
1.180     brouard  10856:   
1.219     brouard  10857:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10858: 
1.219     brouard  10859:   agebase=ageminpar;
                   10860:   agelim=agemaxpar;
1.180     brouard  10861: 
1.227     brouard  10862:   /* i1=pow(2,ncoveff); */
1.234     brouard  10863:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10864:   if (cptcovn < 1){i1=1;}
1.180     brouard  10865: 
1.238     brouard  10866:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10867:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10868:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10869:        continue;
1.235     brouard  10870: 
1.238     brouard  10871:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10872:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10873:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10874:       /* k=k+1; */
                   10875:       /* to clean */
                   10876:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10877:       fprintf(ficrespl,"#******");
                   10878:       printf("#******");
                   10879:       fprintf(ficlog,"#******");
                   10880:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10881:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10882:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10883:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10884:       }
                   10885:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10886:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10887:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10888:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10889:       }
                   10890:       fprintf(ficrespl,"******\n");
                   10891:       printf("******\n");
                   10892:       fprintf(ficlog,"******\n");
                   10893:       if(invalidvarcomb[k]){
                   10894:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10895:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10896:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10897:        continue;
                   10898:       }
1.219     brouard  10899: 
1.238     brouard  10900:       fprintf(ficrespl,"#Age ");
                   10901:       for(j=1;j<=cptcoveff;j++) {
                   10902:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10903:       }
                   10904:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10905:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10906:     
1.238     brouard  10907:       for (age=agebase; age<=agelim; age++){
                   10908:        /* for (age=agebase; age<=agebase; age++){ */
                   10909:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10910:        fprintf(ficrespl,"%.0f ",age );
                   10911:        for(j=1;j<=cptcoveff;j++)
                   10912:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10913:        tot=0.;
                   10914:        for(i=1; i<=nlstate;i++){
                   10915:          tot +=  prlim[i][i];
                   10916:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10917:        }
                   10918:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10919:       } /* Age */
                   10920:       /* was end of cptcod */
                   10921:     } /* cptcov */
                   10922:   } /* nres */
1.219     brouard  10923:   return 0;
1.180     brouard  10924: }
                   10925: 
1.218     brouard  10926: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10927:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10928:        
                   10929:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10930:    * at any age between ageminpar and agemaxpar
                   10931:         */
1.235     brouard  10932:   int i, j, k, i1, nres=0 ;
1.217     brouard  10933:   /* double ftolpl = 1.e-10; */
                   10934:   double age, agebase, agelim;
                   10935:   double tot;
1.218     brouard  10936:   /* double ***mobaverage; */
                   10937:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10938: 
                   10939:   strcpy(fileresplb,"PLB_");
                   10940:   strcat(fileresplb,fileresu);
                   10941:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10942:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10943:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10944:   }
1.288     brouard  10945:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10946:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10947:   pstamp(ficresplb);
1.288     brouard  10948:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10949:   fprintf(ficresplb,"#Age ");
                   10950:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10951:   fprintf(ficresplb,"\n");
                   10952:   
1.218     brouard  10953:   
                   10954:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10955:   
                   10956:   agebase=ageminpar;
                   10957:   agelim=agemaxpar;
                   10958:   
                   10959:   
1.227     brouard  10960:   i1=pow(2,cptcoveff);
1.218     brouard  10961:   if (cptcovn < 1){i1=1;}
1.227     brouard  10962:   
1.238     brouard  10963:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10964:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10965:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10966:        continue;
                   10967:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10968:       fprintf(ficresplb,"#******");
                   10969:       printf("#******");
                   10970:       fprintf(ficlog,"#******");
                   10971:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10972:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10973:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10974:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10975:       }
                   10976:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10977:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10978:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10979:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10980:       }
                   10981:       fprintf(ficresplb,"******\n");
                   10982:       printf("******\n");
                   10983:       fprintf(ficlog,"******\n");
                   10984:       if(invalidvarcomb[k]){
                   10985:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10986:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10987:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10988:        continue;
                   10989:       }
1.218     brouard  10990:     
1.238     brouard  10991:       fprintf(ficresplb,"#Age ");
                   10992:       for(j=1;j<=cptcoveff;j++) {
                   10993:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10994:       }
                   10995:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10996:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10997:     
                   10998:     
1.238     brouard  10999:       for (age=agebase; age<=agelim; age++){
                   11000:        /* for (age=agebase; age<=agebase; age++){ */
                   11001:        if(mobilavproj > 0){
                   11002:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   11003:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  11004:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  11005:        }else if (mobilavproj == 0){
                   11006:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   11007:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   11008:          exit(1);
                   11009:        }else{
                   11010:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  11011:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  11012:          /* printf("TOTOT\n"); */
                   11013:           /* exit(1); */
1.238     brouard  11014:        }
                   11015:        fprintf(ficresplb,"%.0f ",age );
                   11016:        for(j=1;j<=cptcoveff;j++)
                   11017:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11018:        tot=0.;
                   11019:        for(i=1; i<=nlstate;i++){
                   11020:          tot +=  bprlim[i][i];
                   11021:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   11022:        }
                   11023:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   11024:       } /* Age */
                   11025:       /* was end of cptcod */
1.255     brouard  11026:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  11027:     } /* end of any combination */
                   11028:   } /* end of nres */  
1.218     brouard  11029:   /* hBijx(p, bage, fage); */
                   11030:   /* fclose(ficrespijb); */
                   11031:   
                   11032:   return 0;
1.217     brouard  11033: }
1.218     brouard  11034:  
1.180     brouard  11035: int hPijx(double *p, int bage, int fage){
                   11036:     /*------------- h Pij x at various ages ------------*/
                   11037: 
                   11038:   int stepsize;
                   11039:   int agelim;
                   11040:   int hstepm;
                   11041:   int nhstepm;
1.235     brouard  11042:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  11043: 
                   11044:   double agedeb;
                   11045:   double ***p3mat;
                   11046: 
1.201     brouard  11047:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  11048:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   11049:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   11050:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   11051:     }
                   11052:     printf("Computing pij: result on file '%s' \n", filerespij);
                   11053:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   11054:   
                   11055:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   11056:     /*if (stepm<=24) stepsize=2;*/
                   11057: 
                   11058:     agelim=AGESUP;
                   11059:     hstepm=stepsize*YEARM; /* Every year of age */
                   11060:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  11061:                
1.180     brouard  11062:     /* hstepm=1;   aff par mois*/
                   11063:     pstamp(ficrespij);
                   11064:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  11065:     i1= pow(2,cptcoveff);
1.218     brouard  11066:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   11067:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   11068:                /*      k=k+1;  */
1.235     brouard  11069:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11070:     for(k=1; k<=i1;k++){
1.253     brouard  11071:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11072:        continue;
1.183     brouard  11073:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  11074:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  11075:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11076:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   11077:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   11078:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   11079:       }
1.183     brouard  11080:       fprintf(ficrespij,"******\n");
                   11081:       
                   11082:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   11083:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   11084:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   11085:        
                   11086:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  11087:        
1.183     brouard  11088:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   11089:        oldm=oldms;savm=savms;
1.235     brouard  11090:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  11091:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   11092:        for(i=1; i<=nlstate;i++)
                   11093:          for(j=1; j<=nlstate+ndeath;j++)
                   11094:            fprintf(ficrespij," %1d-%1d",i,j);
                   11095:        fprintf(ficrespij,"\n");
                   11096:        for (h=0; h<=nhstepm; h++){
                   11097:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   11098:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  11099:          for(i=1; i<=nlstate;i++)
                   11100:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  11101:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  11102:          fprintf(ficrespij,"\n");
                   11103:        }
1.183     brouard  11104:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   11105:        fprintf(ficrespij,"\n");
                   11106:       }
1.180     brouard  11107:       /*}*/
                   11108:     }
1.218     brouard  11109:     return 0;
1.180     brouard  11110: }
1.218     brouard  11111:  
                   11112:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  11113:     /*------------- h Bij x at various ages ------------*/
                   11114: 
                   11115:   int stepsize;
1.218     brouard  11116:   /* int agelim; */
                   11117:        int ageminl;
1.217     brouard  11118:   int hstepm;
                   11119:   int nhstepm;
1.238     brouard  11120:   int h, i, i1, j, k, nres;
1.218     brouard  11121:        
1.217     brouard  11122:   double agedeb;
                   11123:   double ***p3mat;
1.218     brouard  11124:        
                   11125:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   11126:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   11127:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   11128:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   11129:   }
                   11130:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   11131:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   11132:   
                   11133:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   11134:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  11135:   
1.218     brouard  11136:   /* agelim=AGESUP; */
1.289     brouard  11137:   ageminl=AGEINF; /* was 30 */
1.218     brouard  11138:   hstepm=stepsize*YEARM; /* Every year of age */
                   11139:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   11140:   
                   11141:   /* hstepm=1;   aff par mois*/
                   11142:   pstamp(ficrespijb);
1.255     brouard  11143:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  11144:   i1= pow(2,cptcoveff);
1.218     brouard  11145:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   11146:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   11147:   /*   k=k+1;  */
1.238     brouard  11148:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   11149:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11150:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  11151:        continue;
                   11152:       fprintf(ficrespijb,"\n#****** ");
                   11153:       for(j=1;j<=cptcoveff;j++)
                   11154:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11155:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11156:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11157:       }
                   11158:       fprintf(ficrespijb,"******\n");
1.264     brouard  11159:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  11160:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   11161:        continue;
                   11162:       }
                   11163:       
                   11164:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   11165:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   11166:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
1.297     brouard  11167:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm+0.1)-1; /* Typically 20 years = 20*12/6=40 or 55*12/24=27.5-1.1=>27 */
                   11168:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 or 28*/
1.238     brouard  11169:        
                   11170:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   11171:        
1.266     brouard  11172:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   11173:        /* and memory limitations if stepm is small */
                   11174: 
1.238     brouard  11175:        /* oldm=oldms;savm=savms; */
                   11176:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  11177:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  11178:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  11179:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  11180:        for(i=1; i<=nlstate;i++)
                   11181:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  11182:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  11183:        fprintf(ficrespijb,"\n");
1.238     brouard  11184:        for (h=0; h<=nhstepm; h++){
                   11185:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   11186:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   11187:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   11188:          for(i=1; i<=nlstate;i++)
                   11189:            for(j=1; j<=nlstate+ndeath;j++)
                   11190:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   11191:          fprintf(ficrespijb,"\n");
                   11192:        }
                   11193:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   11194:        fprintf(ficrespijb,"\n");
                   11195:       } /* end age deb */
                   11196:     } /* end combination */
                   11197:   } /* end nres */
1.218     brouard  11198:   return 0;
                   11199:  } /*  hBijx */
1.217     brouard  11200: 
1.180     brouard  11201: 
1.136     brouard  11202: /***********************************************/
                   11203: /**************** Main Program *****************/
                   11204: /***********************************************/
                   11205: 
                   11206: int main(int argc, char *argv[])
                   11207: {
                   11208: #ifdef GSL
                   11209:   const gsl_multimin_fminimizer_type *T;
                   11210:   size_t iteri = 0, it;
                   11211:   int rval = GSL_CONTINUE;
                   11212:   int status = GSL_SUCCESS;
                   11213:   double ssval;
                   11214: #endif
                   11215:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  11216:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   11217:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  11218:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  11219:   int jj, ll, li, lj, lk;
1.136     brouard  11220:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  11221:   int num_filled;
1.136     brouard  11222:   int itimes;
                   11223:   int NDIM=2;
                   11224:   int vpopbased=0;
1.235     brouard  11225:   int nres=0;
1.258     brouard  11226:   int endishere=0;
1.277     brouard  11227:   int noffset=0;
1.274     brouard  11228:   int ncurrv=0; /* Temporary variable */
                   11229:   
1.164     brouard  11230:   char ca[32], cb[32];
1.136     brouard  11231:   /*  FILE *fichtm; *//* Html File */
                   11232:   /* FILE *ficgp;*/ /*Gnuplot File */
                   11233:   struct stat info;
1.191     brouard  11234:   double agedeb=0.;
1.194     brouard  11235: 
                   11236:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  11237:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  11238: 
1.165     brouard  11239:   double fret;
1.191     brouard  11240:   double dum=0.; /* Dummy variable */
1.136     brouard  11241:   double ***p3mat;
1.218     brouard  11242:   /* double ***mobaverage; */
1.319     brouard  11243:   double wald;
1.164     brouard  11244: 
                   11245:   char line[MAXLINE];
1.197     brouard  11246:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   11247: 
1.234     brouard  11248:   char  modeltemp[MAXLINE];
1.230     brouard  11249:   char resultline[MAXLINE];
                   11250:   
1.136     brouard  11251:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  11252:   char *tok, *val; /* pathtot */
1.290     brouard  11253:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  11254:   int c,  h , cpt, c2;
1.191     brouard  11255:   int jl=0;
                   11256:   int i1, j1, jk, stepsize=0;
1.194     brouard  11257:   int count=0;
                   11258: 
1.164     brouard  11259:   int *tab; 
1.136     brouard  11260:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.296     brouard  11261:   /* double anprojd, mprojd, jprojd; /\* For eventual projections *\/ */
                   11262:   /* double anprojf, mprojf, jprojf; */
                   11263:   /* double jintmean,mintmean,aintmean;   */
                   11264:   int prvforecast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11265:   int prvbackcast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11266:   double yrfproj= 10.0; /* Number of years of forward projections */
                   11267:   double yrbproj= 10.0; /* Number of years of backward projections */
                   11268:   int prevbcast=0; /* defined as global for mlikeli and mle, replacing backcast */
1.136     brouard  11269:   int mobilav=0,popforecast=0;
1.191     brouard  11270:   int hstepm=0, nhstepm=0;
1.136     brouard  11271:   int agemortsup;
                   11272:   float  sumlpop=0.;
                   11273:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   11274:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   11275: 
1.191     brouard  11276:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  11277:   double ftolpl=FTOL;
                   11278:   double **prlim;
1.217     brouard  11279:   double **bprlim;
1.317     brouard  11280:   double ***param; /* Matrix of parameters, param[i][j][k] param=ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel) 
                   11281:                     state of origin, state of destination including death, for each covariate: constante, age, and V1 V2 etc. */
1.251     brouard  11282:   double ***paramstart; /* Matrix of starting parameter values */
                   11283:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  11284:   double **matcov; /* Matrix of covariance */
1.203     brouard  11285:   double **hess; /* Hessian matrix */
1.136     brouard  11286:   double ***delti3; /* Scale */
                   11287:   double *delti; /* Scale */
                   11288:   double ***eij, ***vareij;
                   11289:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  11290: 
1.136     brouard  11291:   double *epj, vepp;
1.164     brouard  11292: 
1.273     brouard  11293:   double dateprev1, dateprev2;
1.296     brouard  11294:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0, dateprojd=0, dateprojf=0;
                   11295:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0, datebackd=0, datebackf=0;
                   11296: 
1.217     brouard  11297: 
1.136     brouard  11298:   double **ximort;
1.145     brouard  11299:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  11300:   int *dcwave;
                   11301: 
1.164     brouard  11302:   char z[1]="c";
1.136     brouard  11303: 
                   11304:   /*char  *strt;*/
                   11305:   char strtend[80];
1.126     brouard  11306: 
1.164     brouard  11307: 
1.126     brouard  11308: /*   setlocale (LC_ALL, ""); */
                   11309: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   11310: /*   textdomain (PACKAGE); */
                   11311: /*   setlocale (LC_CTYPE, ""); */
                   11312: /*   setlocale (LC_MESSAGES, ""); */
                   11313: 
                   11314:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  11315:   rstart_time = time(NULL);  
                   11316:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   11317:   start_time = *localtime(&rstart_time);
1.126     brouard  11318:   curr_time=start_time;
1.157     brouard  11319:   /*tml = *localtime(&start_time.tm_sec);*/
                   11320:   /* strcpy(strstart,asctime(&tml)); */
                   11321:   strcpy(strstart,asctime(&start_time));
1.126     brouard  11322: 
                   11323: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  11324: /*  tp.tm_sec = tp.tm_sec +86400; */
                   11325: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  11326: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   11327: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   11328: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  11329: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  11330: /*   strt=asctime(&tmg); */
                   11331: /*   printf("Time(after) =%s",strstart);  */
                   11332: /*  (void) time (&time_value);
                   11333: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   11334: *  tm = *localtime(&time_value);
                   11335: *  strstart=asctime(&tm);
                   11336: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   11337: */
                   11338: 
                   11339:   nberr=0; /* Number of errors and warnings */
                   11340:   nbwarn=0;
1.184     brouard  11341: #ifdef WIN32
                   11342:   _getcwd(pathcd, size);
                   11343: #else
1.126     brouard  11344:   getcwd(pathcd, size);
1.184     brouard  11345: #endif
1.191     brouard  11346:   syscompilerinfo(0);
1.196     brouard  11347:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  11348:   if(argc <=1){
                   11349:     printf("\nEnter the parameter file name: ");
1.205     brouard  11350:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   11351:       printf("ERROR Empty parameter file name\n");
                   11352:       goto end;
                   11353:     }
1.126     brouard  11354:     i=strlen(pathr);
                   11355:     if(pathr[i-1]=='\n')
                   11356:       pathr[i-1]='\0';
1.156     brouard  11357:     i=strlen(pathr);
1.205     brouard  11358:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  11359:       pathr[i-1]='\0';
1.205     brouard  11360:     }
                   11361:     i=strlen(pathr);
                   11362:     if( i==0 ){
                   11363:       printf("ERROR Empty parameter file name\n");
                   11364:       goto end;
                   11365:     }
                   11366:     for (tok = pathr; tok != NULL; ){
1.126     brouard  11367:       printf("Pathr |%s|\n",pathr);
                   11368:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   11369:       printf("val= |%s| pathr=%s\n",val,pathr);
                   11370:       strcpy (pathtot, val);
                   11371:       if(pathr[0] == '\0') break; /* Dirty */
                   11372:     }
                   11373:   }
1.281     brouard  11374:   else if (argc<=2){
                   11375:     strcpy(pathtot,argv[1]);
                   11376:   }
1.126     brouard  11377:   else{
                   11378:     strcpy(pathtot,argv[1]);
1.281     brouard  11379:     strcpy(z,argv[2]);
                   11380:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  11381:   }
                   11382:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   11383:   /*cygwin_split_path(pathtot,path,optionfile);
                   11384:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   11385:   /* cutv(path,optionfile,pathtot,'\\');*/
                   11386: 
                   11387:   /* Split argv[0], imach program to get pathimach */
                   11388:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   11389:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11390:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11391:  /*   strcpy(pathimach,argv[0]); */
                   11392:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   11393:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   11394:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  11395: #ifdef WIN32
                   11396:   _chdir(path); /* Can be a relative path */
                   11397:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   11398: #else
1.126     brouard  11399:   chdir(path); /* Can be a relative path */
1.184     brouard  11400:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   11401: #endif
                   11402:   printf("Current directory %s!\n",pathcd);
1.126     brouard  11403:   strcpy(command,"mkdir ");
                   11404:   strcat(command,optionfilefiname);
                   11405:   if((outcmd=system(command)) != 0){
1.169     brouard  11406:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  11407:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   11408:     /* fclose(ficlog); */
                   11409: /*     exit(1); */
                   11410:   }
                   11411: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   11412: /*     perror("mkdir"); */
                   11413: /*   } */
                   11414: 
                   11415:   /*-------- arguments in the command line --------*/
                   11416: 
1.186     brouard  11417:   /* Main Log file */
1.126     brouard  11418:   strcat(filelog, optionfilefiname);
                   11419:   strcat(filelog,".log");    /* */
                   11420:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   11421:     printf("Problem with logfile %s\n",filelog);
                   11422:     goto end;
                   11423:   }
                   11424:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  11425:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  11426:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   11427:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   11428:  path=%s \n\
                   11429:  optionfile=%s\n\
                   11430:  optionfilext=%s\n\
1.156     brouard  11431:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  11432: 
1.197     brouard  11433:   syscompilerinfo(1);
1.167     brouard  11434: 
1.126     brouard  11435:   printf("Local time (at start):%s",strstart);
                   11436:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   11437:   fflush(ficlog);
                   11438: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  11439: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  11440: 
                   11441:   /* */
                   11442:   strcpy(fileres,"r");
                   11443:   strcat(fileres, optionfilefiname);
1.201     brouard  11444:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  11445:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  11446:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  11447: 
1.186     brouard  11448:   /* Main ---------arguments file --------*/
1.126     brouard  11449: 
                   11450:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  11451:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   11452:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  11453:     fflush(ficlog);
1.149     brouard  11454:     /* goto end; */
                   11455:     exit(70); 
1.126     brouard  11456:   }
                   11457: 
                   11458:   strcpy(filereso,"o");
1.201     brouard  11459:   strcat(filereso,fileresu);
1.126     brouard  11460:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   11461:     printf("Problem with Output resultfile: %s\n", filereso);
                   11462:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   11463:     fflush(ficlog);
                   11464:     goto end;
                   11465:   }
1.278     brouard  11466:       /*-------- Rewriting parameter file ----------*/
                   11467:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   11468:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   11469:   strcat(rfileres,".");    /* */
                   11470:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11471:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   11472:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11473:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   11474:     fflush(ficlog);
                   11475:     goto end;
                   11476:   }
                   11477:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  11478: 
1.278     brouard  11479:                                      
1.126     brouard  11480:   /* Reads comments: lines beginning with '#' */
                   11481:   numlinepar=0;
1.277     brouard  11482:   /* Is it a BOM UTF-8 Windows file? */
                   11483:   /* First parameter line */
1.197     brouard  11484:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  11485:     noffset=0;
                   11486:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   11487:     {
                   11488:       noffset=noffset+3;
                   11489:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11490:     }
1.302     brouard  11491: /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   11492:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
1.277     brouard  11493:     {
                   11494:       noffset=noffset+2;
                   11495:       printf("# File is an UTF16BE BOM file\n");
                   11496:     }
                   11497:     else if( line[0] == 0 && line[1] == 0)
                   11498:     {
                   11499:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11500:        noffset=noffset+4;
                   11501:        printf("# File is an UTF16BE BOM file\n");
                   11502:       }
                   11503:     } else{
                   11504:       ;/*printf(" Not a BOM file\n");*/
                   11505:     }
                   11506:   
1.197     brouard  11507:     /* If line starts with a # it is a comment */
1.277     brouard  11508:     if (line[noffset] == '#') {
1.197     brouard  11509:       numlinepar++;
                   11510:       fputs(line,stdout);
                   11511:       fputs(line,ficparo);
1.278     brouard  11512:       fputs(line,ficres);
1.197     brouard  11513:       fputs(line,ficlog);
                   11514:       continue;
                   11515:     }else
                   11516:       break;
                   11517:   }
                   11518:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11519:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11520:     if (num_filled != 5) {
                   11521:       printf("Should be 5 parameters\n");
1.283     brouard  11522:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11523:     }
1.126     brouard  11524:     numlinepar++;
1.197     brouard  11525:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11526:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11527:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11528:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11529:   }
                   11530:   /* Second parameter line */
                   11531:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11532:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11533:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11534:     if (line[0] == '#') {
                   11535:       numlinepar++;
1.283     brouard  11536:       printf("%s",line);
                   11537:       fprintf(ficres,"%s",line);
                   11538:       fprintf(ficparo,"%s",line);
                   11539:       fprintf(ficlog,"%s",line);
1.197     brouard  11540:       continue;
                   11541:     }else
                   11542:       break;
                   11543:   }
1.223     brouard  11544:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11545:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11546:     if (num_filled != 11) {
                   11547:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11548:       printf("but line=%s\n",line);
1.283     brouard  11549:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11550:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11551:     }
1.286     brouard  11552:     if( lastpass > maxwav){
                   11553:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11554:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11555:       fflush(ficlog);
                   11556:       goto end;
                   11557:     }
                   11558:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11559:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11560:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11561:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11562:   }
1.203     brouard  11563:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11564:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11565:   /* Third parameter line */
                   11566:   while(fgets(line, MAXLINE, ficpar)) {
                   11567:     /* If line starts with a # it is a comment */
                   11568:     if (line[0] == '#') {
                   11569:       numlinepar++;
1.283     brouard  11570:       printf("%s",line);
                   11571:       fprintf(ficres,"%s",line);
                   11572:       fprintf(ficparo,"%s",line);
                   11573:       fprintf(ficlog,"%s",line);
1.197     brouard  11574:       continue;
                   11575:     }else
                   11576:       break;
                   11577:   }
1.201     brouard  11578:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11579:     if (num_filled != 1){
1.302     brouard  11580:       printf("ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
                   11581:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
1.197     brouard  11582:       model[0]='\0';
                   11583:       goto end;
                   11584:     }
                   11585:     else{
                   11586:       if (model[0]=='+'){
                   11587:        for(i=1; i<=strlen(model);i++)
                   11588:          modeltemp[i-1]=model[i];
1.201     brouard  11589:        strcpy(model,modeltemp); 
1.197     brouard  11590:       }
                   11591:     }
1.199     brouard  11592:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11593:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11594:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11595:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11596:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11597:   }
                   11598:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11599:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11600:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11601:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11602:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11603:   fflush(ficlog);
1.190     brouard  11604:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11605:   if(model[0]=='#'){
1.279     brouard  11606:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11607:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11608:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11609:     if(mle != -1){
1.279     brouard  11610:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11611:       exit(1);
                   11612:     }
                   11613:   }
1.126     brouard  11614:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11615:     ungetc(c,ficpar);
                   11616:     fgets(line, MAXLINE, ficpar);
                   11617:     numlinepar++;
1.195     brouard  11618:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11619:       z[0]=line[1];
                   11620:     }
                   11621:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11622:     fputs(line, stdout);
                   11623:     //puts(line);
1.126     brouard  11624:     fputs(line,ficparo);
                   11625:     fputs(line,ficlog);
                   11626:   }
                   11627:   ungetc(c,ficpar);
                   11628: 
                   11629:    
1.290     brouard  11630:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11631:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11632:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11633:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11634:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11635:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11636:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11637:   */
                   11638:   if (strlen(model)>1) 
1.187     brouard  11639:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11640:   else
1.187     brouard  11641:     ncovmodel=2; /* Constant and age */
1.133     brouard  11642:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11643:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11644:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11645:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11646:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11647:     fflush(stdout);
                   11648:     fclose (ficlog);
                   11649:     goto end;
                   11650:   }
1.126     brouard  11651:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11652:   delti=delti3[1][1];
                   11653:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11654:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11655: /* We could also provide initial parameters values giving by simple logistic regression 
                   11656:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11657:       /* for(i=1;i<nlstate;i++){ */
                   11658:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11659:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11660:       /* } */
1.126     brouard  11661:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11662:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11663:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11664:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11665:     fclose (ficparo);
                   11666:     fclose (ficlog);
                   11667:     goto end;
                   11668:     exit(0);
1.220     brouard  11669:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11670:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11671:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11672:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11673:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11674:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11675:     hess=matrix(1,npar,1,npar);
1.220     brouard  11676:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11677:     /* Read guessed parameters */
1.126     brouard  11678:     /* Reads comments: lines beginning with '#' */
                   11679:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11680:       ungetc(c,ficpar);
                   11681:       fgets(line, MAXLINE, ficpar);
                   11682:       numlinepar++;
1.141     brouard  11683:       fputs(line,stdout);
1.126     brouard  11684:       fputs(line,ficparo);
                   11685:       fputs(line,ficlog);
                   11686:     }
                   11687:     ungetc(c,ficpar);
                   11688:     
                   11689:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11690:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11691:     for(i=1; i <=nlstate; i++){
1.234     brouard  11692:       j=0;
1.126     brouard  11693:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11694:        if(jj==i) continue;
                   11695:        j++;
1.292     brouard  11696:        while((c=getc(ficpar))=='#' && c!= EOF){
                   11697:          ungetc(c,ficpar);
                   11698:          fgets(line, MAXLINE, ficpar);
                   11699:          numlinepar++;
                   11700:          fputs(line,stdout);
                   11701:          fputs(line,ficparo);
                   11702:          fputs(line,ficlog);
                   11703:        }
                   11704:        ungetc(c,ficpar);
1.234     brouard  11705:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11706:        if ((i1 != i) || (j1 != jj)){
                   11707:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11708: It might be a problem of design; if ncovcol and the model are correct\n \
                   11709: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11710:          exit(1);
                   11711:        }
                   11712:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11713:        if(mle==1)
                   11714:          printf("%1d%1d",i,jj);
                   11715:        fprintf(ficlog,"%1d%1d",i,jj);
                   11716:        for(k=1; k<=ncovmodel;k++){
                   11717:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11718:          if(mle==1){
                   11719:            printf(" %lf",param[i][j][k]);
                   11720:            fprintf(ficlog," %lf",param[i][j][k]);
                   11721:          }
                   11722:          else
                   11723:            fprintf(ficlog," %lf",param[i][j][k]);
                   11724:          fprintf(ficparo," %lf",param[i][j][k]);
                   11725:        }
                   11726:        fscanf(ficpar,"\n");
                   11727:        numlinepar++;
                   11728:        if(mle==1)
                   11729:          printf("\n");
                   11730:        fprintf(ficlog,"\n");
                   11731:        fprintf(ficparo,"\n");
1.126     brouard  11732:       }
                   11733:     }  
                   11734:     fflush(ficlog);
1.234     brouard  11735:     
1.251     brouard  11736:     /* Reads parameters values */
1.126     brouard  11737:     p=param[1][1];
1.251     brouard  11738:     pstart=paramstart[1][1];
1.126     brouard  11739:     
                   11740:     /* Reads comments: lines beginning with '#' */
                   11741:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11742:       ungetc(c,ficpar);
                   11743:       fgets(line, MAXLINE, ficpar);
                   11744:       numlinepar++;
1.141     brouard  11745:       fputs(line,stdout);
1.126     brouard  11746:       fputs(line,ficparo);
                   11747:       fputs(line,ficlog);
                   11748:     }
                   11749:     ungetc(c,ficpar);
                   11750: 
                   11751:     for(i=1; i <=nlstate; i++){
                   11752:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11753:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11754:        if ( (i1-i) * (j1-j) != 0){
                   11755:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11756:          exit(1);
                   11757:        }
                   11758:        printf("%1d%1d",i,j);
                   11759:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11760:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11761:        for(k=1; k<=ncovmodel;k++){
                   11762:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11763:          printf(" %le",delti3[i][j][k]);
                   11764:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11765:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11766:        }
                   11767:        fscanf(ficpar,"\n");
                   11768:        numlinepar++;
                   11769:        printf("\n");
                   11770:        fprintf(ficparo,"\n");
                   11771:        fprintf(ficlog,"\n");
1.126     brouard  11772:       }
                   11773:     }
                   11774:     fflush(ficlog);
1.234     brouard  11775:     
1.145     brouard  11776:     /* Reads covariance matrix */
1.126     brouard  11777:     delti=delti3[1][1];
1.220     brouard  11778:                
                   11779:                
1.126     brouard  11780:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11781:                
1.126     brouard  11782:     /* Reads comments: lines beginning with '#' */
                   11783:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11784:       ungetc(c,ficpar);
                   11785:       fgets(line, MAXLINE, ficpar);
                   11786:       numlinepar++;
1.141     brouard  11787:       fputs(line,stdout);
1.126     brouard  11788:       fputs(line,ficparo);
                   11789:       fputs(line,ficlog);
                   11790:     }
                   11791:     ungetc(c,ficpar);
1.220     brouard  11792:                
1.126     brouard  11793:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11794:     hess=matrix(1,npar,1,npar);
1.131     brouard  11795:     for(i=1; i <=npar; i++)
                   11796:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11797:                
1.194     brouard  11798:     /* Scans npar lines */
1.126     brouard  11799:     for(i=1; i <=npar; i++){
1.226     brouard  11800:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11801:       if(count != 3){
1.226     brouard  11802:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11803: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11804: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11805:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11806: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11807: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11808:        exit(1);
1.220     brouard  11809:       }else{
1.226     brouard  11810:        if(mle==1)
                   11811:          printf("%1d%1d%d",i1,j1,jk);
                   11812:       }
                   11813:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11814:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11815:       for(j=1; j <=i; j++){
1.226     brouard  11816:        fscanf(ficpar," %le",&matcov[i][j]);
                   11817:        if(mle==1){
                   11818:          printf(" %.5le",matcov[i][j]);
                   11819:        }
                   11820:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11821:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11822:       }
                   11823:       fscanf(ficpar,"\n");
                   11824:       numlinepar++;
                   11825:       if(mle==1)
1.220     brouard  11826:                                printf("\n");
1.126     brouard  11827:       fprintf(ficlog,"\n");
                   11828:       fprintf(ficparo,"\n");
                   11829:     }
1.194     brouard  11830:     /* End of read covariance matrix npar lines */
1.126     brouard  11831:     for(i=1; i <=npar; i++)
                   11832:       for(j=i+1;j<=npar;j++)
1.226     brouard  11833:        matcov[i][j]=matcov[j][i];
1.126     brouard  11834:     
                   11835:     if(mle==1)
                   11836:       printf("\n");
                   11837:     fprintf(ficlog,"\n");
                   11838:     
                   11839:     fflush(ficlog);
                   11840:     
                   11841:   }    /* End of mle != -3 */
1.218     brouard  11842:   
1.186     brouard  11843:   /*  Main data
                   11844:    */
1.290     brouard  11845:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11846:   /* num=lvector(1,n); */
                   11847:   /* moisnais=vector(1,n); */
                   11848:   /* annais=vector(1,n); */
                   11849:   /* moisdc=vector(1,n); */
                   11850:   /* andc=vector(1,n); */
                   11851:   /* weight=vector(1,n); */
                   11852:   /* agedc=vector(1,n); */
                   11853:   /* cod=ivector(1,n); */
                   11854:   /* for(i=1;i<=n;i++){ */
                   11855:   num=lvector(firstobs,lastobs);
                   11856:   moisnais=vector(firstobs,lastobs);
                   11857:   annais=vector(firstobs,lastobs);
                   11858:   moisdc=vector(firstobs,lastobs);
                   11859:   andc=vector(firstobs,lastobs);
                   11860:   weight=vector(firstobs,lastobs);
                   11861:   agedc=vector(firstobs,lastobs);
                   11862:   cod=ivector(firstobs,lastobs);
                   11863:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11864:     num[i]=0;
                   11865:     moisnais[i]=0;
                   11866:     annais[i]=0;
                   11867:     moisdc[i]=0;
                   11868:     andc[i]=0;
                   11869:     agedc[i]=0;
                   11870:     cod[i]=0;
                   11871:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11872:   }
1.290     brouard  11873:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11874:   anint=matrix(1,maxwav,firstobs,lastobs);
                   11875:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11876:   tab=ivector(1,NCOVMAX);
1.144     brouard  11877:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11878:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11879: 
1.136     brouard  11880:   /* Reads data from file datafile */
                   11881:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11882:     goto end;
                   11883: 
                   11884:   /* Calculation of the number of parameters from char model */
1.234     brouard  11885:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11886:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11887:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11888:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11889:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11890:   */
                   11891:   
                   11892:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11893:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11894:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11895:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11896:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11897:   TvarF=ivector(1,NCOVMAX); /*  */
                   11898:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11899:   TvarV=ivector(1,NCOVMAX); /*  */
                   11900:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11901:   TvarA=ivector(1,NCOVMAX); /*  */
                   11902:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11903:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11904:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11905:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11906:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11907:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11908:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11909:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11910:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11911: 
1.230     brouard  11912:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11913:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11914:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11915:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11916:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11917:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11918:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11919:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11920:   */
                   11921:   /* For model-covariate k tells which data-covariate to use but
                   11922:     because this model-covariate is a construction we invent a new column
                   11923:     ncovcol + k1
                   11924:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11925:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11926:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11927:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11928:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11929:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11930:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11931:   */
1.145     brouard  11932:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11933:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11934:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11935:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11936:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11937:                         4 covariates (3 plus signs)
                   11938:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11939:                      */  
1.230     brouard  11940:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11941:                                * individual dummy, fixed or varying:
                   11942:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11943:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11944:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11945:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11946:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11947:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11948:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11949:                                * individual quantitative, fixed or varying:
                   11950:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11951:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11952:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11953: /* Main decodemodel */
                   11954: 
1.187     brouard  11955: 
1.223     brouard  11956:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11957:     goto end;
                   11958: 
1.137     brouard  11959:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11960:     nbwarn++;
                   11961:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11962:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11963:   }
1.136     brouard  11964:     /*  if(mle==1){*/
1.137     brouard  11965:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11966:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11967:   }
                   11968: 
                   11969:     /*-calculation of age at interview from date of interview and age at death -*/
                   11970:   agev=matrix(1,maxwav,1,imx);
                   11971: 
                   11972:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11973:     goto end;
                   11974: 
1.126     brouard  11975: 
1.136     brouard  11976:   agegomp=(int)agemin;
1.290     brouard  11977:   free_vector(moisnais,firstobs,lastobs);
                   11978:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11979:   /* free_matrix(mint,1,maxwav,1,n);
                   11980:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11981:   /* free_vector(moisdc,1,n); */
                   11982:   /* free_vector(andc,1,n); */
1.145     brouard  11983:   /* */
                   11984:   
1.126     brouard  11985:   wav=ivector(1,imx);
1.214     brouard  11986:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11987:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11988:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11989:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11990:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11991:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11992:    
                   11993:   /* Concatenates waves */
1.214     brouard  11994:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11995:      Death is a valid wave (if date is known).
                   11996:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11997:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11998:      and mw[mi+1][i]. dh depends on stepm.
                   11999:   */
                   12000: 
1.126     brouard  12001:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  12002:   /* Concatenates waves */
1.145     brouard  12003:  
1.290     brouard  12004:   free_vector(moisdc,firstobs,lastobs);
                   12005:   free_vector(andc,firstobs,lastobs);
1.215     brouard  12006: 
1.126     brouard  12007:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   12008:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   12009:   ncodemax[1]=1;
1.145     brouard  12010:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  12011:   cptcoveff=0;
1.220     brouard  12012:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   12013:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  12014:   }
                   12015:   
                   12016:   ncovcombmax=pow(2,cptcoveff);
                   12017:   invalidvarcomb=ivector(1, ncovcombmax); 
                   12018:   for(i=1;i<ncovcombmax;i++)
                   12019:     invalidvarcomb[i]=0;
                   12020:   
1.211     brouard  12021:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  12022:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  12023:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  12024:   
1.200     brouard  12025:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  12026:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  12027:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  12028:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   12029:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   12030:    * (currently 0 or 1) in the data.
                   12031:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   12032:    * corresponding modality (h,j).
                   12033:    */
                   12034: 
1.145     brouard  12035:   h=0;
                   12036:   /*if (cptcovn > 0) */
1.126     brouard  12037:   m=pow(2,cptcoveff);
                   12038:  
1.144     brouard  12039:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  12040:           * For k=4 covariates, h goes from 1 to m=2**k
                   12041:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   12042:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  12043:           *     h\k   1     2     3     4
1.143     brouard  12044:           *______________________________  
                   12045:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   12046:           *     2     2     1     1     1
                   12047:           *     3 i=2 1     2     1     1
                   12048:           *     4     2     2     1     1
                   12049:           *     5 i=3 1 i=2 1     2     1
                   12050:           *     6     2     1     2     1
                   12051:           *     7 i=4 1     2     2     1
                   12052:           *     8     2     2     2     1
1.197     brouard  12053:           *     9 i=5 1 i=3 1 i=2 1     2
                   12054:           *    10     2     1     1     2
                   12055:           *    11 i=6 1     2     1     2
                   12056:           *    12     2     2     1     2
                   12057:           *    13 i=7 1 i=4 1     2     2    
                   12058:           *    14     2     1     2     2
                   12059:           *    15 i=8 1     2     2     2
                   12060:           *    16     2     2     2     2
1.143     brouard  12061:           */
1.212     brouard  12062:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  12063:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   12064:      * and the value of each covariate?
                   12065:      * V1=1, V2=1, V3=2, V4=1 ?
                   12066:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   12067:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   12068:      * In order to get the real value in the data, we use nbcode
                   12069:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   12070:      * We are keeping this crazy system in order to be able (in the future?) 
                   12071:      * to have more than 2 values (0 or 1) for a covariate.
                   12072:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   12073:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   12074:      *              bbbbbbbb
                   12075:      *              76543210     
                   12076:      *   h-1        00000101 (6-1=5)
1.219     brouard  12077:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  12078:      *           &
                   12079:      *     1        00000001 (1)
1.219     brouard  12080:      *              00000000        = 1 & ((h-1) >> (k-1))
                   12081:      *          +1= 00000001 =1 
1.211     brouard  12082:      *
                   12083:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   12084:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   12085:      *    >>k'            11
                   12086:      *          &   00000001
                   12087:      *            = 00000001
                   12088:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   12089:      * Reverse h=6 and m=16?
                   12090:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   12091:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   12092:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   12093:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   12094:      * V3=decodtabm(14,3,2**4)=2
                   12095:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   12096:      *(h-1) >> (j-1)    0011 =13 >> 2
                   12097:      *          &1 000000001
                   12098:      *           = 000000001
                   12099:      *         +1= 000000010 =2
                   12100:      *                  2211
                   12101:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   12102:      *                  V3=2
1.220     brouard  12103:                 * codtabm and decodtabm are identical
1.211     brouard  12104:      */
                   12105: 
1.145     brouard  12106: 
                   12107:  free_ivector(Ndum,-1,NCOVMAX);
                   12108: 
                   12109: 
1.126     brouard  12110:     
1.186     brouard  12111:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  12112:   strcpy(optionfilegnuplot,optionfilefiname);
                   12113:   if(mle==-3)
1.201     brouard  12114:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  12115:   strcat(optionfilegnuplot,".gp");
                   12116: 
                   12117:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   12118:     printf("Problem with file %s",optionfilegnuplot);
                   12119:   }
                   12120:   else{
1.204     brouard  12121:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  12122:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  12123:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   12124:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  12125:   }
                   12126:   /*  fclose(ficgp);*/
1.186     brouard  12127: 
                   12128: 
                   12129:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  12130: 
                   12131:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   12132:   if(mle==-3)
1.201     brouard  12133:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  12134:   strcat(optionfilehtm,".htm");
                   12135:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  12136:     printf("Problem with %s \n",optionfilehtm);
                   12137:     exit(0);
1.126     brouard  12138:   }
                   12139: 
                   12140:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   12141:   strcat(optionfilehtmcov,"-cov.htm");
                   12142:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   12143:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   12144:   }
                   12145:   else{
                   12146:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   12147: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  12148: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  12149:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   12150:   }
                   12151: 
1.213     brouard  12152:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  12153: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   12154: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  12155: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  12156: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  12157: \n\
                   12158: <hr  size=\"2\" color=\"#EC5E5E\">\
                   12159:  <ul><li><h4>Parameter files</h4>\n\
                   12160:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   12161:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   12162:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   12163:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   12164:  - Date and time at start: %s</ul>\n",\
                   12165:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   12166:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   12167:          fileres,fileres,\
                   12168:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   12169:   fflush(fichtm);
                   12170: 
                   12171:   strcpy(pathr,path);
                   12172:   strcat(pathr,optionfilefiname);
1.184     brouard  12173: #ifdef WIN32
                   12174:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   12175: #else
1.126     brouard  12176:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  12177: #endif
                   12178:          
1.126     brouard  12179:   
1.220     brouard  12180:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   12181:                 and for any valid combination of covariates
1.126     brouard  12182:      and prints on file fileres'p'. */
1.251     brouard  12183:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  12184:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  12185: 
                   12186:   fprintf(fichtm,"\n");
1.286     brouard  12187:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  12188:          ftol, stepm);
                   12189:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   12190:   ncurrv=1;
                   12191:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   12192:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   12193:   ncurrv=i;
                   12194:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  12195:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  12196:   ncurrv=i;
                   12197:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  12198:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  12199:   ncurrv=i;
                   12200:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   12201:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   12202:           nlstate, ndeath, maxwav, mle, weightopt);
                   12203: 
                   12204:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   12205: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   12206: 
                   12207:   
1.317     brouard  12208:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Number of (used) observations=%d <br>\n\
1.126     brouard  12209: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   12210: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  12211:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  12212:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  12213:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   12214:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   12215:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   12216:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  12217: 
1.126     brouard  12218:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   12219:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   12220:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   12221: 
                   12222:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  12223:   /* For mortality only */
1.126     brouard  12224:   if (mle==-3){
1.136     brouard  12225:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  12226:     for(i=1;i<=NDIM;i++)
                   12227:       for(j=1;j<=NDIM;j++)
                   12228:        ximort[i][j]=0.;
1.186     brouard  12229:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  12230:     cens=ivector(firstobs,lastobs);
                   12231:     ageexmed=vector(firstobs,lastobs);
                   12232:     agecens=vector(firstobs,lastobs);
                   12233:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  12234:                
1.126     brouard  12235:     for (i=1; i<=imx; i++){
                   12236:       dcwave[i]=-1;
                   12237:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  12238:        if (s[m][i]>nlstate) {
                   12239:          dcwave[i]=m;
                   12240:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   12241:          break;
                   12242:        }
1.126     brouard  12243:     }
1.226     brouard  12244:     
1.126     brouard  12245:     for (i=1; i<=imx; i++) {
                   12246:       if (wav[i]>0){
1.226     brouard  12247:        ageexmed[i]=agev[mw[1][i]][i];
                   12248:        j=wav[i];
                   12249:        agecens[i]=1.; 
                   12250:        
                   12251:        if (ageexmed[i]> 1 && wav[i] > 0){
                   12252:          agecens[i]=agev[mw[j][i]][i];
                   12253:          cens[i]= 1;
                   12254:        }else if (ageexmed[i]< 1) 
                   12255:          cens[i]= -1;
                   12256:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   12257:          cens[i]=0 ;
1.126     brouard  12258:       }
                   12259:       else cens[i]=-1;
                   12260:     }
                   12261:     
                   12262:     for (i=1;i<=NDIM;i++) {
                   12263:       for (j=1;j<=NDIM;j++)
1.226     brouard  12264:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  12265:     }
                   12266:     
1.302     brouard  12267:     p[1]=0.0268; p[NDIM]=0.083;
                   12268:     /* printf("%lf %lf", p[1], p[2]); */
1.126     brouard  12269:     
                   12270:     
1.136     brouard  12271: #ifdef GSL
                   12272:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  12273: #else
1.126     brouard  12274:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  12275: #endif
1.201     brouard  12276:     strcpy(filerespow,"POW-MORT_"); 
                   12277:     strcat(filerespow,fileresu);
1.126     brouard  12278:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   12279:       printf("Problem with resultfile: %s\n", filerespow);
                   12280:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   12281:     }
1.136     brouard  12282: #ifdef GSL
                   12283:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  12284: #else
1.126     brouard  12285:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  12286: #endif
1.126     brouard  12287:     /*  for (i=1;i<=nlstate;i++)
                   12288:        for(j=1;j<=nlstate+ndeath;j++)
                   12289:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   12290:     */
                   12291:     fprintf(ficrespow,"\n");
1.136     brouard  12292: #ifdef GSL
                   12293:     /* gsl starts here */ 
                   12294:     T = gsl_multimin_fminimizer_nmsimplex;
                   12295:     gsl_multimin_fminimizer *sfm = NULL;
                   12296:     gsl_vector *ss, *x;
                   12297:     gsl_multimin_function minex_func;
                   12298: 
                   12299:     /* Initial vertex size vector */
                   12300:     ss = gsl_vector_alloc (NDIM);
                   12301:     
                   12302:     if (ss == NULL){
                   12303:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   12304:     }
                   12305:     /* Set all step sizes to 1 */
                   12306:     gsl_vector_set_all (ss, 0.001);
                   12307: 
                   12308:     /* Starting point */
1.126     brouard  12309:     
1.136     brouard  12310:     x = gsl_vector_alloc (NDIM);
                   12311:     
                   12312:     if (x == NULL){
                   12313:       gsl_vector_free(ss);
                   12314:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   12315:     }
                   12316:   
                   12317:     /* Initialize method and iterate */
                   12318:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  12319:     /*     gsl_vector_set(x, 0, 0.0268); */
                   12320:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  12321:     gsl_vector_set(x, 0, p[1]);
                   12322:     gsl_vector_set(x, 1, p[2]);
                   12323: 
                   12324:     minex_func.f = &gompertz_f;
                   12325:     minex_func.n = NDIM;
                   12326:     minex_func.params = (void *)&p; /* ??? */
                   12327:     
                   12328:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   12329:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   12330:     
                   12331:     printf("Iterations beginning .....\n\n");
                   12332:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   12333: 
                   12334:     iteri=0;
                   12335:     while (rval == GSL_CONTINUE){
                   12336:       iteri++;
                   12337:       status = gsl_multimin_fminimizer_iterate(sfm);
                   12338:       
                   12339:       if (status) printf("error: %s\n", gsl_strerror (status));
                   12340:       fflush(0);
                   12341:       
                   12342:       if (status) 
                   12343:         break;
                   12344:       
                   12345:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   12346:       ssval = gsl_multimin_fminimizer_size (sfm);
                   12347:       
                   12348:       if (rval == GSL_SUCCESS)
                   12349:         printf ("converged to a local maximum at\n");
                   12350:       
                   12351:       printf("%5d ", iteri);
                   12352:       for (it = 0; it < NDIM; it++){
                   12353:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   12354:       }
                   12355:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   12356:     }
                   12357:     
                   12358:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   12359:     
                   12360:     gsl_vector_free(x); /* initial values */
                   12361:     gsl_vector_free(ss); /* inital step size */
                   12362:     for (it=0; it<NDIM; it++){
                   12363:       p[it+1]=gsl_vector_get(sfm->x,it);
                   12364:       fprintf(ficrespow," %.12lf", p[it]);
                   12365:     }
                   12366:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   12367: #endif
                   12368: #ifdef POWELL
                   12369:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   12370: #endif  
1.126     brouard  12371:     fclose(ficrespow);
                   12372:     
1.203     brouard  12373:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  12374: 
                   12375:     for(i=1; i <=NDIM; i++)
                   12376:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  12377:                                matcov[i][j]=matcov[j][i];
1.126     brouard  12378:     
                   12379:     printf("\nCovariance matrix\n ");
1.203     brouard  12380:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  12381:     for(i=1; i <=NDIM; i++) {
                   12382:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  12383:                                printf("%f ",matcov[i][j]);
                   12384:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  12385:       }
1.203     brouard  12386:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  12387:     }
                   12388:     
                   12389:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  12390:     for (i=1;i<=NDIM;i++) {
1.126     brouard  12391:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  12392:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   12393:     }
1.302     brouard  12394:     lsurv=vector(agegomp,AGESUP);
                   12395:     lpop=vector(agegomp,AGESUP);
                   12396:     tpop=vector(agegomp,AGESUP);
1.126     brouard  12397:     lsurv[agegomp]=100000;
                   12398:     
                   12399:     for (k=agegomp;k<=AGESUP;k++) {
                   12400:       agemortsup=k;
                   12401:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   12402:     }
                   12403:     
                   12404:     for (k=agegomp;k<agemortsup;k++)
                   12405:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   12406:     
                   12407:     for (k=agegomp;k<agemortsup;k++){
                   12408:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   12409:       sumlpop=sumlpop+lpop[k];
                   12410:     }
                   12411:     
                   12412:     tpop[agegomp]=sumlpop;
                   12413:     for (k=agegomp;k<(agemortsup-3);k++){
                   12414:       /*  tpop[k+1]=2;*/
                   12415:       tpop[k+1]=tpop[k]-lpop[k];
                   12416:     }
                   12417:     
                   12418:     
                   12419:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   12420:     for (k=agegomp;k<(agemortsup-2);k++) 
                   12421:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   12422:     
                   12423:     
                   12424:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  12425:                ageminpar=50;
                   12426:                agemaxpar=100;
1.194     brouard  12427:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   12428:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12429: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12430: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   12431:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12432: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12433: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12434:     }else{
                   12435:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   12436:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  12437:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  12438:                }
1.201     brouard  12439:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  12440:                     stepm, weightopt,\
                   12441:                     model,imx,p,matcov,agemortsup);
                   12442:     
1.302     brouard  12443:     free_vector(lsurv,agegomp,AGESUP);
                   12444:     free_vector(lpop,agegomp,AGESUP);
                   12445:     free_vector(tpop,agegomp,AGESUP);
1.220     brouard  12446:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  12447:     free_ivector(dcwave,firstobs,lastobs);
                   12448:     free_vector(agecens,firstobs,lastobs);
                   12449:     free_vector(ageexmed,firstobs,lastobs);
                   12450:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  12451: #ifdef GSL
1.136     brouard  12452: #endif
1.186     brouard  12453:   } /* Endof if mle==-3 mortality only */
1.205     brouard  12454:   /* Standard  */
                   12455:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   12456:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12457:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  12458:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  12459:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12460:     for (k=1; k<=npar;k++)
                   12461:       printf(" %d %8.5f",k,p[k]);
                   12462:     printf("\n");
1.205     brouard  12463:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   12464:       /* mlikeli uses func not funcone */
1.247     brouard  12465:       /* for(i=1;i<nlstate;i++){ */
                   12466:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   12467:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   12468:       /* } */
1.205     brouard  12469:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   12470:     }
                   12471:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   12472:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12473:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   12474:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12475:     }
                   12476:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  12477:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12478:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12479:     for (k=1; k<=npar;k++)
                   12480:       printf(" %d %8.5f",k,p[k]);
                   12481:     printf("\n");
                   12482:     
                   12483:     /*--------- results files --------------*/
1.283     brouard  12484:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  12485:     
                   12486:     
                   12487:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
1.319     brouard  12488:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n"); /* Printing model equation */
1.126     brouard  12489:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
1.319     brouard  12490: 
                   12491:     printf("#model=  1      +     age ");
                   12492:     fprintf(ficres,"#model=  1      +     age ");
                   12493:     fprintf(ficlog,"#model=  1      +     age ");
                   12494:     fprintf(fichtm,"\n<ul><li> model=1+age+%s\n \
                   12495: </ul>", model);
                   12496: 
                   12497:     fprintf(fichtm,"\n<table style=\"text-align:center; border: 1px solid\">\n");
                   12498:     fprintf(fichtm, "<tr><th>Model=</th><th>1</th><th>+ age</th>");
                   12499:     if(nagesqr==1){
                   12500:       printf("  + age*age  ");
                   12501:       fprintf(ficres,"  + age*age  ");
                   12502:       fprintf(ficlog,"  + age*age  ");
                   12503:       fprintf(fichtm, "<th>+ age*age</th>");
                   12504:     }
                   12505:     for(j=1;j <=ncovmodel-2;j++){
                   12506:       if(Typevar[j]==0) {
                   12507:        printf("  +      V%d  ",Tvar[j]);
                   12508:        fprintf(ficres,"  +      V%d  ",Tvar[j]);
                   12509:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   12510:        fprintf(fichtm, "<th>+ V%d</th>",Tvar[j]);
                   12511:       }else if(Typevar[j]==1) {
                   12512:        printf("  +    V%d*age ",Tvar[j]);
                   12513:        fprintf(ficres,"  +    V%d*age ",Tvar[j]);
                   12514:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   12515:        fprintf(fichtm, "<th>+  V%d*age</th>",Tvar[j]);
                   12516:       }else if(Typevar[j]==2) {
                   12517:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12518:        fprintf(ficres,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12519:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12520:        fprintf(fichtm, "<th>+  V%d*V%d</th>",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12521:       }
                   12522:     }
                   12523:     printf("\n");
                   12524:     fprintf(ficres,"\n");
                   12525:     fprintf(ficlog,"\n");
                   12526:     fprintf(fichtm, "</tr>");
                   12527:     fprintf(fichtm, "\n");
                   12528:     
                   12529:     
1.126     brouard  12530:     for(i=1,jk=1; i <=nlstate; i++){
                   12531:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  12532:        if (k != i) {
1.319     brouard  12533:          fprintf(fichtm, "<tr>");
1.225     brouard  12534:          printf("%d%d ",i,k);
                   12535:          fprintf(ficlog,"%d%d ",i,k);
                   12536:          fprintf(ficres,"%1d%1d ",i,k);
1.319     brouard  12537:          fprintf(fichtm, "<td>%1d%1d</td>",i,k);
1.225     brouard  12538:          for(j=1; j <=ncovmodel; j++){
                   12539:            printf("%12.7f ",p[jk]);
                   12540:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12541:            fprintf(ficres,"%12.7f ",p[jk]);
1.319     brouard  12542:            fprintf(fichtm, "<td>%12.7f</td>",p[jk]);
1.225     brouard  12543:            jk++; 
                   12544:          }
                   12545:          printf("\n");
                   12546:          fprintf(ficlog,"\n");
                   12547:          fprintf(ficres,"\n");
1.319     brouard  12548:          fprintf(fichtm, "</tr>\n");
1.225     brouard  12549:        }
1.126     brouard  12550:       }
                   12551:     }
1.319     brouard  12552:     /* fprintf(fichtm,"</tr>\n"); */
                   12553:     fprintf(fichtm,"</table>\n");
                   12554:     fprintf(fichtm, "\n");
                   12555: 
1.203     brouard  12556:     if(mle != 0){
                   12557:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12558:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12559:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12560:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12561:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
1.322     brouard  12562:       fprintf(fichtm, "\n<p>The Wald test results are output only if the maximimzation of the Likelihood is performed (mle=1)\n</br>Parameters, Wald tests and Wald-based confidence intervals\n</br> W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n</br> And Wald-based confidence intervals plus and minus 1.96 * W \n </br> It might be better to visualize the covariance matrix. See the page '<a href=\"%s\">Matrix of variance-covariance of one-step probabilities and its graphs</a>'.\n</br>",optionfilehtmcov);
1.319     brouard  12563:       fprintf(fichtm,"\n<table style=\"text-align:center; border: 1px solid\">");
                   12564:       fprintf(fichtm, "\n<tr><th>Model=</th><th>1</th><th>+ age</th>");
                   12565:       if(nagesqr==1){
                   12566:        printf("  + age*age  ");
                   12567:        fprintf(ficres,"  + age*age  ");
                   12568:        fprintf(ficlog,"  + age*age  ");
                   12569:        fprintf(fichtm, "<th>+ age*age</th>");
                   12570:       }
                   12571:       for(j=1;j <=ncovmodel-2;j++){
                   12572:        if(Typevar[j]==0) {
                   12573:          printf("  +      V%d  ",Tvar[j]);
                   12574:          fprintf(fichtm, "<th>+ V%d</th>",Tvar[j]);
                   12575:        }else if(Typevar[j]==1) {
                   12576:          printf("  +    V%d*age ",Tvar[j]);
                   12577:          fprintf(fichtm, "<th>+  V%d*age</th>",Tvar[j]);
                   12578:        }else if(Typevar[j]==2) {
                   12579:          fprintf(fichtm, "<th>+  V%d*V%d</th>",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12580:        }
                   12581:       }
                   12582:       fprintf(fichtm, "</tr>\n");
                   12583:  
1.203     brouard  12584:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12585:        for(k=1; k <=(nlstate+ndeath); k++){
                   12586:          if (k != i) {
1.319     brouard  12587:            fprintf(fichtm, "<tr valign=top>");
1.225     brouard  12588:            printf("%d%d ",i,k);
                   12589:            fprintf(ficlog,"%d%d ",i,k);
1.319     brouard  12590:            fprintf(fichtm, "<td>%1d%1d</td>",i,k);
1.225     brouard  12591:            for(j=1; j <=ncovmodel; j++){
1.319     brouard  12592:              wald=p[jk]/sqrt(matcov[jk][jk]);
1.321     brouard  12593:              printf("%12.7f(%12.7f) sqrt(W)=%8.3f CI=[%12.7f ; %12.7f] ",p[jk],sqrt(matcov[jk][jk]), p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12594:              fprintf(ficlog,"%12.7f(%12.7f) sqrt(W)=%8.3f CI=[%12.7f ; %12.7f] ",p[jk],sqrt(matcov[jk][jk]), p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
1.319     brouard  12595:              if(fabs(wald) > 1.96){
1.321     brouard  12596:                fprintf(fichtm, "<td><b>%12.7f</b></br> (%12.7f)</br>",p[jk],sqrt(matcov[jk][jk]));
1.319     brouard  12597:              }else{
                   12598:                fprintf(fichtm, "<td>%12.7f (%12.7f)</br>",p[jk],sqrt(matcov[jk][jk]));
                   12599:              }
1.321     brouard  12600:              fprintf(fichtm,"sqrt(W)=%8.3f</br>",wald);
1.319     brouard  12601:              fprintf(fichtm,"[%12.7f;%12.7f]</br></td>", p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
1.225     brouard  12602:              jk++; 
                   12603:            }
                   12604:            printf("\n");
                   12605:            fprintf(ficlog,"\n");
1.319     brouard  12606:            fprintf(fichtm, "</tr>\n");
1.225     brouard  12607:          }
                   12608:        }
1.193     brouard  12609:       }
1.203     brouard  12610:     } /* end of hesscov and Wald tests */
1.319     brouard  12611:     fprintf(fichtm,"</table>\n");
1.225     brouard  12612:     
1.203     brouard  12613:     /*  */
1.126     brouard  12614:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12615:     printf("# Scales (for hessian or gradient estimation)\n");
                   12616:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12617:     for(i=1,jk=1; i <=nlstate; i++){
                   12618:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12619:        if (j!=i) {
                   12620:          fprintf(ficres,"%1d%1d",i,j);
                   12621:          printf("%1d%1d",i,j);
                   12622:          fprintf(ficlog,"%1d%1d",i,j);
                   12623:          for(k=1; k<=ncovmodel;k++){
                   12624:            printf(" %.5e",delti[jk]);
                   12625:            fprintf(ficlog," %.5e",delti[jk]);
                   12626:            fprintf(ficres," %.5e",delti[jk]);
                   12627:            jk++;
                   12628:          }
                   12629:          printf("\n");
                   12630:          fprintf(ficlog,"\n");
                   12631:          fprintf(ficres,"\n");
                   12632:        }
1.126     brouard  12633:       }
                   12634:     }
                   12635:     
                   12636:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12637:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12638:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12639:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12640:     /* # 121 Var(a12)\n\ */
                   12641:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12642:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12643:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12644:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12645:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12646:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12647:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12648:     
                   12649:     
                   12650:     /* Just to have a covariance matrix which will be more understandable
                   12651:        even is we still don't want to manage dictionary of variables
                   12652:     */
                   12653:     for(itimes=1;itimes<=2;itimes++){
                   12654:       jj=0;
                   12655:       for(i=1; i <=nlstate; i++){
1.225     brouard  12656:        for(j=1; j <=nlstate+ndeath; j++){
                   12657:          if(j==i) continue;
                   12658:          for(k=1; k<=ncovmodel;k++){
                   12659:            jj++;
                   12660:            ca[0]= k+'a'-1;ca[1]='\0';
                   12661:            if(itimes==1){
                   12662:              if(mle>=1)
                   12663:                printf("#%1d%1d%d",i,j,k);
                   12664:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12665:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12666:            }else{
                   12667:              if(mle>=1)
                   12668:                printf("%1d%1d%d",i,j,k);
                   12669:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12670:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12671:            }
                   12672:            ll=0;
                   12673:            for(li=1;li <=nlstate; li++){
                   12674:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12675:                if(lj==li) continue;
                   12676:                for(lk=1;lk<=ncovmodel;lk++){
                   12677:                  ll++;
                   12678:                  if(ll<=jj){
                   12679:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12680:                    if(ll<jj){
                   12681:                      if(itimes==1){
                   12682:                        if(mle>=1)
                   12683:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12684:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12685:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12686:                      }else{
                   12687:                        if(mle>=1)
                   12688:                          printf(" %.5e",matcov[jj][ll]); 
                   12689:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12690:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12691:                      }
                   12692:                    }else{
                   12693:                      if(itimes==1){
                   12694:                        if(mle>=1)
                   12695:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12696:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12697:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12698:                      }else{
                   12699:                        if(mle>=1)
                   12700:                          printf(" %.7e",matcov[jj][ll]); 
                   12701:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12702:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12703:                      }
                   12704:                    }
                   12705:                  }
                   12706:                } /* end lk */
                   12707:              } /* end lj */
                   12708:            } /* end li */
                   12709:            if(mle>=1)
                   12710:              printf("\n");
                   12711:            fprintf(ficlog,"\n");
                   12712:            fprintf(ficres,"\n");
                   12713:            numlinepar++;
                   12714:          } /* end k*/
                   12715:        } /*end j */
1.126     brouard  12716:       } /* end i */
                   12717:     } /* end itimes */
                   12718:     
                   12719:     fflush(ficlog);
                   12720:     fflush(ficres);
1.225     brouard  12721:     while(fgets(line, MAXLINE, ficpar)) {
                   12722:       /* If line starts with a # it is a comment */
                   12723:       if (line[0] == '#') {
                   12724:        numlinepar++;
                   12725:        fputs(line,stdout);
                   12726:        fputs(line,ficparo);
                   12727:        fputs(line,ficlog);
1.299     brouard  12728:        fputs(line,ficres);
1.225     brouard  12729:        continue;
                   12730:       }else
                   12731:        break;
                   12732:     }
                   12733:     
1.209     brouard  12734:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12735:     /*   ungetc(c,ficpar); */
                   12736:     /*   fgets(line, MAXLINE, ficpar); */
                   12737:     /*   fputs(line,stdout); */
                   12738:     /*   fputs(line,ficparo); */
                   12739:     /* } */
                   12740:     /* ungetc(c,ficpar); */
1.126     brouard  12741:     
                   12742:     estepm=0;
1.209     brouard  12743:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12744:       
                   12745:       if (num_filled != 6) {
                   12746:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12747:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12748:        goto end;
                   12749:       }
                   12750:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12751:     }
                   12752:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12753:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12754:     
1.209     brouard  12755:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12756:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12757:     if (fage <= 2) {
                   12758:       bage = ageminpar;
                   12759:       fage = agemaxpar;
                   12760:     }
                   12761:     
                   12762:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12763:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12764:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12765:                
1.186     brouard  12766:     /* Other stuffs, more or less useful */    
1.254     brouard  12767:     while(fgets(line, MAXLINE, ficpar)) {
                   12768:       /* If line starts with a # it is a comment */
                   12769:       if (line[0] == '#') {
                   12770:        numlinepar++;
                   12771:        fputs(line,stdout);
                   12772:        fputs(line,ficparo);
                   12773:        fputs(line,ficlog);
1.299     brouard  12774:        fputs(line,ficres);
1.254     brouard  12775:        continue;
                   12776:       }else
                   12777:        break;
                   12778:     }
                   12779: 
                   12780:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12781:       
                   12782:       if (num_filled != 7) {
                   12783:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12784:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12785:        goto end;
                   12786:       }
                   12787:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12788:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12789:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12790:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12791:     }
1.254     brouard  12792: 
                   12793:     while(fgets(line, MAXLINE, ficpar)) {
                   12794:       /* If line starts with a # it is a comment */
                   12795:       if (line[0] == '#') {
                   12796:        numlinepar++;
                   12797:        fputs(line,stdout);
                   12798:        fputs(line,ficparo);
                   12799:        fputs(line,ficlog);
1.299     brouard  12800:        fputs(line,ficres);
1.254     brouard  12801:        continue;
                   12802:       }else
                   12803:        break;
1.126     brouard  12804:     }
                   12805:     
                   12806:     
                   12807:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12808:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12809:     
1.254     brouard  12810:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12811:       if (num_filled != 1) {
                   12812:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12813:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12814:        goto end;
                   12815:       }
                   12816:       printf("pop_based=%d\n",popbased);
                   12817:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12818:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12819:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12820:     }
                   12821:      
1.258     brouard  12822:     /* Results */
1.307     brouard  12823:     endishere=0;
1.258     brouard  12824:     nresult=0;
1.308     brouard  12825:     parameterline=0;
1.258     brouard  12826:     do{
                   12827:       if(!fgets(line, MAXLINE, ficpar)){
                   12828:        endishere=1;
1.308     brouard  12829:        parameterline=15;
1.258     brouard  12830:       }else if (line[0] == '#') {
                   12831:        /* If line starts with a # it is a comment */
1.254     brouard  12832:        numlinepar++;
                   12833:        fputs(line,stdout);
                   12834:        fputs(line,ficparo);
                   12835:        fputs(line,ficlog);
1.299     brouard  12836:        fputs(line,ficres);
1.254     brouard  12837:        continue;
1.258     brouard  12838:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12839:        parameterline=11;
1.296     brouard  12840:       else if(sscanf(line,"prevbackcast=%[^\n]\n",modeltemp))
1.258     brouard  12841:        parameterline=12;
1.307     brouard  12842:       else if(sscanf(line,"result:%[^\n]\n",modeltemp)){
1.258     brouard  12843:        parameterline=13;
1.307     brouard  12844:       }
1.258     brouard  12845:       else{
                   12846:        parameterline=14;
1.254     brouard  12847:       }
1.308     brouard  12848:       switch (parameterline){ /* =0 only if only comments */
1.258     brouard  12849:       case 11:
1.296     brouard  12850:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12851:                  fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.258     brouard  12852:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12853:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12854:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12855:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12856:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12857:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
1.296     brouard  12858:           prvforecast = 1;
                   12859:        } 
                   12860:        else if((num_filled=sscanf(line,"prevforecast=%d yearsfproj=%lf mobil_average=%d\n",&prevfcast,&yrfproj,&mobilavproj)) !=EOF){/* && (num_filled == 3))*/
1.313     brouard  12861:          printf("prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12862:          fprintf(ficlog,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12863:          fprintf(ficres,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
1.296     brouard  12864:           prvforecast = 2;
                   12865:        }
                   12866:        else {
                   12867:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearsfproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12868:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12869:          goto end;
1.258     brouard  12870:        }
1.254     brouard  12871:        break;
1.258     brouard  12872:       case 12:
1.296     brouard  12873:        if((num_filled=sscanf(line,"prevbackcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&prevbcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12874:           fprintf(ficparo,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12875:          printf("prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12876:          fprintf(ficlog,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12877:          fprintf(ficres,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12878:          /* day and month of back2 are not used but only year anback2.*/
1.273     brouard  12879:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12880:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.296     brouard  12881:           prvbackcast = 1;
                   12882:        } 
                   12883:        else if((num_filled=sscanf(line,"prevbackcast=%d yearsbproj=%lf mobil_average=%d\n",&prevbcast,&yrbproj,&mobilavproj)) ==3){/* && (num_filled == 3))*/
1.313     brouard  12884:          printf("prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12885:          fprintf(ficlog,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12886:          fprintf(ficres,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
1.296     brouard  12887:           prvbackcast = 2;
                   12888:        }
                   12889:        else {
                   12890:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearsbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12891:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12892:          goto end;
1.258     brouard  12893:        }
1.230     brouard  12894:        break;
1.258     brouard  12895:       case 13:
1.307     brouard  12896:        num_filled=sscanf(line,"result:%[^\n]\n",resultline);
                   12897:        nresult++; /* Sum of resultlines */
                   12898:        printf("Result %d: result:%s\n",nresult, resultline);
1.318     brouard  12899:        if(nresult > MAXRESULTLINESPONE-1){
                   12900:          printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINESPONE-1,nresult,rfileres);
                   12901:          fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINESPONE-1,nresult,rfileres);
1.307     brouard  12902:          goto end;
                   12903:        }
1.310     brouard  12904:        if(!decoderesult(resultline, nresult)){ /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.314     brouard  12905:          fprintf(ficparo,"result: %s\n",resultline);
                   12906:          fprintf(ficres,"result: %s\n",resultline);
                   12907:          fprintf(ficlog,"result: %s\n",resultline);
1.310     brouard  12908:        } else
                   12909:          goto end;
1.307     brouard  12910:        break;
                   12911:       case 14:
                   12912:        printf("Error: Unknown command '%s'\n",line);
                   12913:        fprintf(ficlog,"Error: Unknown command '%s'\n",line);
1.314     brouard  12914:        if(line[0] == ' ' || line[0] == '\n'){
                   12915:          printf("It should not be an empty line '%s'\n",line);
                   12916:          fprintf(ficlog,"It should not be an empty line '%s'\n",line);
                   12917:        }         
1.307     brouard  12918:        if(ncovmodel >=2 && nresult==0 ){
                   12919:          printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
                   12920:          fprintf(ficlog,"ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12921:        }
1.307     brouard  12922:        /* goto end; */
                   12923:        break;
1.308     brouard  12924:       case 15:
                   12925:        printf("End of resultlines.\n");
                   12926:        fprintf(ficlog,"End of resultlines.\n");
                   12927:        break;
                   12928:       default: /* parameterline =0 */
1.307     brouard  12929:        nresult=1;
                   12930:        decoderesult(".",nresult ); /* No covariate */
1.258     brouard  12931:       } /* End switch parameterline */
                   12932:     }while(endishere==0); /* End do */
1.126     brouard  12933:     
1.230     brouard  12934:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12935:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12936:     
                   12937:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12938:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12939:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12940: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12941: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12942:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12943: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12944: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12945:     }else{
1.270     brouard  12946:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
1.296     brouard  12947:       /* It seems that anprojd which is computed from the mean year at interview which is known yet because of freqsummary */
                   12948:       /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */ /* Done in freqsummary */
                   12949:       if(prvforecast==1){
                   12950:         dateprojd=(jproj1+12*mproj1+365*anproj1)/365;
                   12951:         jprojd=jproj1;
                   12952:         mprojd=mproj1;
                   12953:         anprojd=anproj1;
                   12954:         dateprojf=(jproj2+12*mproj2+365*anproj2)/365;
                   12955:         jprojf=jproj2;
                   12956:         mprojf=mproj2;
                   12957:         anprojf=anproj2;
                   12958:       } else if(prvforecast == 2){
                   12959:         dateprojd=dateintmean;
                   12960:         date2dmy(dateprojd,&jprojd, &mprojd, &anprojd);
                   12961:         dateprojf=dateintmean+yrfproj;
                   12962:         date2dmy(dateprojf,&jprojf, &mprojf, &anprojf);
                   12963:       }
                   12964:       if(prvbackcast==1){
                   12965:         datebackd=(jback1+12*mback1+365*anback1)/365;
                   12966:         jbackd=jback1;
                   12967:         mbackd=mback1;
                   12968:         anbackd=anback1;
                   12969:         datebackf=(jback2+12*mback2+365*anback2)/365;
                   12970:         jbackf=jback2;
                   12971:         mbackf=mback2;
                   12972:         anbackf=anback2;
                   12973:       } else if(prvbackcast == 2){
                   12974:         datebackd=dateintmean;
                   12975:         date2dmy(datebackd,&jbackd, &mbackd, &anbackd);
                   12976:         datebackf=dateintmean-yrbproj;
                   12977:         date2dmy(datebackf,&jbackf, &mbackf, &anbackf);
                   12978:       }
                   12979:       
                   12980:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, prevbcast, pathc,p, (int)anprojd-bage, (int)anbackd-fage);
1.220     brouard  12981:     }
                   12982:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.296     brouard  12983:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,prevbcast, estepm, \
                   12984:                 jprev1,mprev1,anprev1,dateprev1, dateprojd, datebackd,jprev2,mprev2,anprev2,dateprev2,dateprojf, datebackf);
1.220     brouard  12985:                
1.225     brouard  12986:     /*------------ free_vector  -------------*/
                   12987:     /*  chdir(path); */
1.220     brouard  12988:                
1.215     brouard  12989:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12990:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12991:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12992:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  12993:     free_lvector(num,firstobs,lastobs);
                   12994:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  12995:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12996:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12997:     fclose(ficparo);
                   12998:     fclose(ficres);
1.220     brouard  12999:                
                   13000:                
1.186     brouard  13001:     /* Other results (useful)*/
1.220     brouard  13002:                
                   13003:                
1.126     brouard  13004:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  13005:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   13006:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  13007:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  13008:     fclose(ficrespl);
                   13009: 
                   13010:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  13011:     /*#include "hpijx.h"*/
                   13012:     hPijx(p, bage, fage);
1.145     brouard  13013:     fclose(ficrespij);
1.227     brouard  13014:     
1.220     brouard  13015:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  13016:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  13017:     k=1;
1.126     brouard  13018:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  13019:     
1.269     brouard  13020:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   13021:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   13022:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  13023:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  13024:        for(k=1;k<=ncovcombmax;k++)
                   13025:          probs[i][j][k]=0.;
1.269     brouard  13026:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   13027:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  13028:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  13029:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   13030:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  13031:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  13032:          for(k=1;k<=ncovcombmax;k++)
                   13033:            mobaverages[i][j][k]=0.;
1.219     brouard  13034:       mobaverage=mobaverages;
                   13035:       if (mobilav!=0) {
1.235     brouard  13036:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  13037:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  13038:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   13039:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   13040:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   13041:        }
1.269     brouard  13042:       } else if (mobilavproj !=0) {
1.235     brouard  13043:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  13044:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  13045:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   13046:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   13047:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   13048:        }
1.269     brouard  13049:       }else{
                   13050:        printf("Internal error moving average\n");
                   13051:        fflush(stdout);
                   13052:        exit(1);
1.219     brouard  13053:       }
                   13054:     }/* end if moving average */
1.227     brouard  13055:     
1.126     brouard  13056:     /*---------- Forecasting ------------------*/
1.296     brouard  13057:     if(prevfcast==1){ 
                   13058:       /*   /\*    if(stepm ==1){*\/ */
                   13059:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   13060:       /*This done previously after freqsummary.*/
                   13061:       /*   dateprojd=(jproj1+12*mproj1+365*anproj1)/365; */
                   13062:       /*   dateprojf=(jproj2+12*mproj2+365*anproj2)/365; */
                   13063:       
                   13064:       /* } else if (prvforecast==2){ */
                   13065:       /*   /\*    if(stepm ==1){*\/ */
                   13066:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   13067:       /* } */
                   13068:       /*prevforecast(fileresu, dateintmean, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);*/
                   13069:       prevforecast(fileresu,dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, p, cptcoveff);
1.126     brouard  13070:     }
1.269     brouard  13071: 
1.296     brouard  13072:     /* Prevbcasting */
                   13073:     if(prevbcast==1){
1.219     brouard  13074:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   13075:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   13076:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   13077: 
                   13078:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   13079: 
                   13080:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  13081: 
1.219     brouard  13082:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   13083:       fclose(ficresplb);
                   13084: 
1.222     brouard  13085:       hBijx(p, bage, fage, mobaverage);
                   13086:       fclose(ficrespijb);
1.219     brouard  13087: 
1.296     brouard  13088:       /* /\* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, *\/ */
                   13089:       /* /\*                  mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); *\/ */
                   13090:       /* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, */
                   13091:       /*                      mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
                   13092:       prevbackforecast(fileresu, mobaverage, dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2,
                   13093:                       mobilavproj, bage, fage, firstpass, lastpass, p, cptcoveff);
                   13094: 
                   13095:       
1.269     brouard  13096:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  13097: 
                   13098:       
1.269     brouard  13099:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  13100:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   13101:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   13102:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.296     brouard  13103:     }    /* end  Prevbcasting */
1.268     brouard  13104:  
1.186     brouard  13105:  
                   13106:     /* ------ Other prevalence ratios------------ */
1.126     brouard  13107: 
1.215     brouard  13108:     free_ivector(wav,1,imx);
                   13109:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   13110:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   13111:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  13112:                
                   13113:                
1.127     brouard  13114:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  13115:                
1.201     brouard  13116:     strcpy(filerese,"E_");
                   13117:     strcat(filerese,fileresu);
1.126     brouard  13118:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   13119:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   13120:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   13121:     }
1.208     brouard  13122:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   13123:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  13124: 
                   13125:     pstamp(ficreseij);
1.219     brouard  13126:                
1.235     brouard  13127:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   13128:     if (cptcovn < 1){i1=1;}
                   13129:     
                   13130:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   13131:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  13132:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  13133:        continue;
1.219     brouard  13134:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  13135:       printf("\n#****** ");
1.225     brouard  13136:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  13137:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  13138:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13139:       }
                   13140:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13141:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13142:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  13143:       }
                   13144:       fprintf(ficreseij,"******\n");
1.235     brouard  13145:       printf("******\n");
1.219     brouard  13146:       
                   13147:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   13148:       oldm=oldms;savm=savms;
1.235     brouard  13149:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  13150:       
1.219     brouard  13151:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  13152:     }
                   13153:     fclose(ficreseij);
1.208     brouard  13154:     printf("done evsij\n");fflush(stdout);
                   13155:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  13156: 
1.218     brouard  13157:                
1.227     brouard  13158:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  13159:                
1.201     brouard  13160:     strcpy(filerest,"T_");
                   13161:     strcat(filerest,fileresu);
1.127     brouard  13162:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   13163:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   13164:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   13165:     }
1.208     brouard  13166:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   13167:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  13168:     strcpy(fileresstde,"STDE_");
                   13169:     strcat(fileresstde,fileresu);
1.126     brouard  13170:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  13171:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   13172:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  13173:     }
1.227     brouard  13174:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   13175:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  13176: 
1.201     brouard  13177:     strcpy(filerescve,"CVE_");
                   13178:     strcat(filerescve,fileresu);
1.126     brouard  13179:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  13180:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   13181:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  13182:     }
1.227     brouard  13183:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   13184:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  13185: 
1.201     brouard  13186:     strcpy(fileresv,"V_");
                   13187:     strcat(fileresv,fileresu);
1.126     brouard  13188:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   13189:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   13190:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   13191:     }
1.227     brouard  13192:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   13193:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  13194: 
1.235     brouard  13195:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   13196:     if (cptcovn < 1){i1=1;}
                   13197:     
                   13198:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   13199:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  13200:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  13201:        continue;
1.321     brouard  13202:       printf("\n# model %s \n#****** Result for:", model);
                   13203:       fprintf(ficrest,"\n# model %s \n#****** Result for:", model);
                   13204:       fprintf(ficlog,"\n# model %s \n#****** Result for:", model);
1.227     brouard  13205:       for(j=1;j<=cptcoveff;j++){ 
                   13206:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13207:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13208:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13209:       }
1.235     brouard  13210:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13211:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13212:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13213:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13214:       }        
1.208     brouard  13215:       fprintf(ficrest,"******\n");
1.227     brouard  13216:       fprintf(ficlog,"******\n");
                   13217:       printf("******\n");
1.208     brouard  13218:       
                   13219:       fprintf(ficresstdeij,"\n#****** ");
                   13220:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  13221:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  13222:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13223:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  13224:       }
1.235     brouard  13225:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13226:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13227:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13228:       }        
1.208     brouard  13229:       fprintf(ficresstdeij,"******\n");
                   13230:       fprintf(ficrescveij,"******\n");
                   13231:       
                   13232:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  13233:       /* pstamp(ficresvij); */
1.225     brouard  13234:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  13235:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  13236:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13237:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13238:       }        
1.208     brouard  13239:       fprintf(ficresvij,"******\n");
                   13240:       
                   13241:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   13242:       oldm=oldms;savm=savms;
1.235     brouard  13243:       printf(" cvevsij ");
                   13244:       fprintf(ficlog, " cvevsij ");
                   13245:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  13246:       printf(" end cvevsij \n ");
                   13247:       fprintf(ficlog, " end cvevsij \n ");
                   13248:       
                   13249:       /*
                   13250:        */
                   13251:       /* goto endfree; */
                   13252:       
                   13253:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   13254:       pstamp(ficrest);
                   13255:       
1.269     brouard  13256:       epj=vector(1,nlstate+1);
1.208     brouard  13257:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  13258:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   13259:        cptcod= 0; /* To be deleted */
                   13260:        printf("varevsij vpopbased=%d \n",vpopbased);
                   13261:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  13262:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  13263:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   13264:        if(vpopbased==1)
                   13265:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   13266:        else
1.288     brouard  13267:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  13268:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   13269:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   13270:        fprintf(ficrest,"\n");
                   13271:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  13272:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   13273:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  13274:        for(age=bage; age <=fage ;age++){
1.235     brouard  13275:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  13276:          if (vpopbased==1) {
                   13277:            if(mobilav ==0){
                   13278:              for(i=1; i<=nlstate;i++)
                   13279:                prlim[i][i]=probs[(int)age][i][k];
                   13280:            }else{ /* mobilav */ 
                   13281:              for(i=1; i<=nlstate;i++)
                   13282:                prlim[i][i]=mobaverage[(int)age][i][k];
                   13283:            }
                   13284:          }
1.219     brouard  13285:          
1.227     brouard  13286:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   13287:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   13288:          /* printf(" age %4.0f ",age); */
                   13289:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   13290:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   13291:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   13292:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   13293:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   13294:            }
                   13295:            epj[nlstate+1] +=epj[j];
                   13296:          }
                   13297:          /* printf(" age %4.0f \n",age); */
1.219     brouard  13298:          
1.227     brouard  13299:          for(i=1, vepp=0.;i <=nlstate;i++)
                   13300:            for(j=1;j <=nlstate;j++)
                   13301:              vepp += vareij[i][j][(int)age];
                   13302:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   13303:          for(j=1;j <=nlstate;j++){
                   13304:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   13305:          }
                   13306:          fprintf(ficrest,"\n");
                   13307:        }
1.208     brouard  13308:       } /* End vpopbased */
1.269     brouard  13309:       free_vector(epj,1,nlstate+1);
1.208     brouard  13310:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   13311:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  13312:       printf("done selection\n");fflush(stdout);
                   13313:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  13314:       
1.235     brouard  13315:     } /* End k selection */
1.227     brouard  13316: 
                   13317:     printf("done State-specific expectancies\n");fflush(stdout);
                   13318:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   13319: 
1.288     brouard  13320:     /* variance-covariance of forward period prevalence*/
1.269     brouard  13321:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  13322: 
1.227     brouard  13323:     
1.290     brouard  13324:     free_vector(weight,firstobs,lastobs);
1.227     brouard  13325:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  13326:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   13327:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   13328:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   13329:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  13330:     free_ivector(tab,1,NCOVMAX);
                   13331:     fclose(ficresstdeij);
                   13332:     fclose(ficrescveij);
                   13333:     fclose(ficresvij);
                   13334:     fclose(ficrest);
                   13335:     fclose(ficpar);
                   13336:     
                   13337:     
1.126     brouard  13338:     /*---------- End : free ----------------*/
1.219     brouard  13339:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  13340:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   13341:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  13342:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   13343:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  13344:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  13345:   /* endfree:*/
                   13346:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   13347:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   13348:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  13349:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   13350:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   13351:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   13352:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  13353:   free_matrix(matcov,1,npar,1,npar);
                   13354:   free_matrix(hess,1,npar,1,npar);
                   13355:   /*free_vector(delti,1,npar);*/
                   13356:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   13357:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  13358:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  13359:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   13360:   
                   13361:   free_ivector(ncodemax,1,NCOVMAX);
                   13362:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   13363:   free_ivector(Dummy,-1,NCOVMAX);
                   13364:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  13365:   free_ivector(DummyV,1,NCOVMAX);
                   13366:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  13367:   free_ivector(Typevar,-1,NCOVMAX);
                   13368:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  13369:   free_ivector(TvarsQ,1,NCOVMAX);
                   13370:   free_ivector(TvarsQind,1,NCOVMAX);
                   13371:   free_ivector(TvarsD,1,NCOVMAX);
                   13372:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  13373:   free_ivector(TvarFD,1,NCOVMAX);
                   13374:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  13375:   free_ivector(TvarF,1,NCOVMAX);
                   13376:   free_ivector(TvarFind,1,NCOVMAX);
                   13377:   free_ivector(TvarV,1,NCOVMAX);
                   13378:   free_ivector(TvarVind,1,NCOVMAX);
                   13379:   free_ivector(TvarA,1,NCOVMAX);
                   13380:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  13381:   free_ivector(TvarFQ,1,NCOVMAX);
                   13382:   free_ivector(TvarFQind,1,NCOVMAX);
                   13383:   free_ivector(TvarVD,1,NCOVMAX);
                   13384:   free_ivector(TvarVDind,1,NCOVMAX);
                   13385:   free_ivector(TvarVQ,1,NCOVMAX);
                   13386:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  13387:   free_ivector(Tvarsel,1,NCOVMAX);
                   13388:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  13389:   free_ivector(Tposprod,1,NCOVMAX);
                   13390:   free_ivector(Tprod,1,NCOVMAX);
                   13391:   free_ivector(Tvaraff,1,NCOVMAX);
                   13392:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   13393:   free_ivector(Tage,1,NCOVMAX);
                   13394:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  13395:   free_ivector(TmodelInvind,1,NCOVMAX);
                   13396:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  13397:   
                   13398:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   13399:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  13400:   fflush(fichtm);
                   13401:   fflush(ficgp);
                   13402:   
1.227     brouard  13403:   
1.126     brouard  13404:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  13405:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   13406:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  13407:   }else{
                   13408:     printf("End of Imach\n");
                   13409:     fprintf(ficlog,"End of Imach\n");
                   13410:   }
                   13411:   printf("See log file on %s\n",filelog);
                   13412:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  13413:   /*(void) gettimeofday(&end_time,&tzp);*/
                   13414:   rend_time = time(NULL);  
                   13415:   end_time = *localtime(&rend_time);
                   13416:   /* tml = *localtime(&end_time.tm_sec); */
                   13417:   strcpy(strtend,asctime(&end_time));
1.126     brouard  13418:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   13419:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  13420:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  13421:   
1.157     brouard  13422:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   13423:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   13424:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  13425:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   13426: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   13427:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13428:   fclose(fichtm);
                   13429:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13430:   fclose(fichtmcov);
                   13431:   fclose(ficgp);
                   13432:   fclose(ficlog);
                   13433:   /*------ End -----------*/
1.227     brouard  13434:   
1.281     brouard  13435: 
                   13436: /* Executes gnuplot */
1.227     brouard  13437:   
                   13438:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  13439: #ifdef WIN32
1.227     brouard  13440:   if (_chdir(pathcd) != 0)
                   13441:     printf("Can't move to directory %s!\n",path);
                   13442:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  13443: #else
1.227     brouard  13444:     if(chdir(pathcd) != 0)
                   13445:       printf("Can't move to directory %s!\n", path);
                   13446:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  13447: #endif 
1.126     brouard  13448:     printf("Current directory %s!\n",pathcd);
                   13449:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   13450:   sprintf(plotcmd,"gnuplot");
1.157     brouard  13451: #ifdef _WIN32
1.126     brouard  13452:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   13453: #endif
                   13454:   if(!stat(plotcmd,&info)){
1.158     brouard  13455:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13456:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  13457:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  13458:     }else
                   13459:       strcpy(pplotcmd,plotcmd);
1.157     brouard  13460: #ifdef __unix
1.126     brouard  13461:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   13462:     if(!stat(plotcmd,&info)){
1.158     brouard  13463:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13464:     }else
                   13465:       strcpy(pplotcmd,plotcmd);
                   13466: #endif
                   13467:   }else
                   13468:     strcpy(pplotcmd,plotcmd);
                   13469:   
                   13470:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  13471:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.292     brouard  13472:   strcpy(pplotcmd,plotcmd);
1.227     brouard  13473:   
1.126     brouard  13474:   if((outcmd=system(plotcmd)) != 0){
1.292     brouard  13475:     printf("Error in gnuplot, command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  13476:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  13477:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.292     brouard  13478:     if((outcmd=system(plotcmd)) != 0){
1.153     brouard  13479:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.292     brouard  13480:       strcpy(plotcmd,pplotcmd);
                   13481:     }
1.126     brouard  13482:   }
1.158     brouard  13483:   printf(" Successful, please wait...");
1.126     brouard  13484:   while (z[0] != 'q') {
                   13485:     /* chdir(path); */
1.154     brouard  13486:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  13487:     scanf("%s",z);
                   13488: /*     if (z[0] == 'c') system("./imach"); */
                   13489:     if (z[0] == 'e') {
1.158     brouard  13490: #ifdef __APPLE__
1.152     brouard  13491:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  13492: #elif __linux
                   13493:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  13494: #else
1.152     brouard  13495:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  13496: #endif
                   13497:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   13498:       system(pplotcmd);
1.126     brouard  13499:     }
                   13500:     else if (z[0] == 'g') system(plotcmd);
                   13501:     else if (z[0] == 'q') exit(0);
                   13502:   }
1.227     brouard  13503: end:
1.126     brouard  13504:   while (z[0] != 'q') {
1.195     brouard  13505:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  13506:     scanf("%s",z);
                   13507:   }
1.283     brouard  13508:   printf("End\n");
1.282     brouard  13509:   exit(0);
1.126     brouard  13510: }

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