Annotation of imach/src/imach.c, revision 1.325

1.325   ! brouard     1: /* $Id: imach.c,v 1.324 2022/07/23 17:44:26 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.325   ! brouard     4:   Revision 1.324  2022/07/23 17:44:26  brouard
        !             5:   *** empty log message ***
        !             6: 
1.324     brouard     7:   Revision 1.323  2022/07/22 12:30:08  brouard
                      8:   *  imach.c (Module): Output of Wald test in the htm file and not only in the log.
                      9: 
1.323     brouard    10:   Revision 1.322  2022/07/22 12:27:48  brouard
                     11:   *  imach.c (Module): Output of Wald test in the htm file and not only in the log.
                     12: 
1.322     brouard    13:   Revision 1.321  2022/07/22 12:04:24  brouard
                     14:   Summary: r28
                     15: 
                     16:   *  imach.c (Module): Output of Wald test in the htm file and not only in the log.
                     17: 
1.321     brouard    18:   Revision 1.320  2022/06/02 05:10:11  brouard
                     19:   *** empty log message ***
                     20: 
1.320     brouard    21:   Revision 1.319  2022/06/02 04:45:11  brouard
                     22:   * imach.c (Module): Adding the Wald tests from the log to the main
                     23:   htm for better display of the maximum likelihood estimators.
                     24: 
1.319     brouard    25:   Revision 1.318  2022/05/24 08:10:59  brouard
                     26:   * imach.c (Module): Some attempts to find a bug of wrong estimates
                     27:   of confidencce intervals with product in the equation modelC
                     28: 
1.318     brouard    29:   Revision 1.317  2022/05/15 15:06:23  brouard
                     30:   * imach.c (Module):  Some minor improvements
                     31: 
1.317     brouard    32:   Revision 1.316  2022/05/11 15:11:31  brouard
                     33:   Summary: r27
                     34: 
1.316     brouard    35:   Revision 1.315  2022/05/11 15:06:32  brouard
                     36:   *** empty log message ***
                     37: 
1.315     brouard    38:   Revision 1.314  2022/04/13 17:43:09  brouard
                     39:   * imach.c (Module): Adding link to text data files
                     40: 
1.314     brouard    41:   Revision 1.313  2022/04/11 15:57:42  brouard
                     42:   * imach.c (Module): Error in rewriting the 'r' file with yearsfproj or yearsbproj fixed
                     43: 
1.313     brouard    44:   Revision 1.312  2022/04/05 21:24:39  brouard
                     45:   *** empty log message ***
                     46: 
1.312     brouard    47:   Revision 1.311  2022/04/05 21:03:51  brouard
                     48:   Summary: Fixed quantitative covariates
                     49: 
                     50:          Fixed covariates (dummy or quantitative)
                     51:        with missing values have never been allowed but are ERRORS and
                     52:        program quits. Standard deviations of fixed covariates were
                     53:        wrongly computed. Mean and standard deviations of time varying
                     54:        covariates are still not computed.
                     55: 
1.311     brouard    56:   Revision 1.310  2022/03/17 08:45:53  brouard
                     57:   Summary: 99r25
                     58: 
                     59:   Improving detection of errors: result lines should be compatible with
                     60:   the model.
                     61: 
1.310     brouard    62:   Revision 1.309  2021/05/20 12:39:14  brouard
                     63:   Summary: Version 0.99r24
                     64: 
1.309     brouard    65:   Revision 1.308  2021/03/31 13:11:57  brouard
                     66:   Summary: Version 0.99r23
                     67: 
                     68: 
                     69:   * imach.c (Module): Still bugs in the result loop. Thank to Holly Benett
                     70: 
1.308     brouard    71:   Revision 1.307  2021/03/08 18:11:32  brouard
                     72:   Summary: 0.99r22 fixed bug on result:
                     73: 
1.307     brouard    74:   Revision 1.306  2021/02/20 15:44:02  brouard
                     75:   Summary: Version 0.99r21
                     76: 
                     77:   * imach.c (Module): Fix bug on quitting after result lines!
                     78:   (Module): Version 0.99r21
                     79: 
1.306     brouard    80:   Revision 1.305  2021/02/20 15:28:30  brouard
                     81:   * imach.c (Module): Fix bug on quitting after result lines!
                     82: 
1.305     brouard    83:   Revision 1.304  2021/02/12 11:34:20  brouard
                     84:   * imach.c (Module): The use of a Windows BOM (huge) file is now an error
                     85: 
1.304     brouard    86:   Revision 1.303  2021/02/11 19:50:15  brouard
                     87:   *  (Module): imach.c Someone entered 'results:' instead of 'result:'. Now it is an error which is printed.
                     88: 
1.303     brouard    89:   Revision 1.302  2020/02/22 21:00:05  brouard
                     90:   *  (Module): imach.c Update mle=-3 (for computing Life expectancy
                     91:   and life table from the data without any state)
                     92: 
1.302     brouard    93:   Revision 1.301  2019/06/04 13:51:20  brouard
                     94:   Summary: Error in 'r'parameter file backcast yearsbproj instead of yearsfproj
                     95: 
1.301     brouard    96:   Revision 1.300  2019/05/22 19:09:45  brouard
                     97:   Summary: version 0.99r19 of May 2019
                     98: 
1.300     brouard    99:   Revision 1.299  2019/05/22 18:37:08  brouard
                    100:   Summary: Cleaned 0.99r19
                    101: 
1.299     brouard   102:   Revision 1.298  2019/05/22 18:19:56  brouard
                    103:   *** empty log message ***
                    104: 
1.298     brouard   105:   Revision 1.297  2019/05/22 17:56:10  brouard
                    106:   Summary: Fix bug by moving date2dmy and nhstepm which gaefin=-1
                    107: 
1.297     brouard   108:   Revision 1.296  2019/05/20 13:03:18  brouard
                    109:   Summary: Projection syntax simplified
                    110: 
                    111: 
                    112:   We can now start projections, forward or backward, from the mean date
                    113:   of inteviews up to or down to a number of years of projection:
                    114:   prevforecast=1 yearsfproj=15.3 mobil_average=0
                    115:   or
                    116:   prevforecast=1 starting-proj-date=1/1/2007 final-proj-date=12/31/2017 mobil_average=0
                    117:   or
                    118:   prevbackcast=1 yearsbproj=12.3 mobil_average=1
                    119:   or
                    120:   prevbackcast=1 starting-back-date=1/10/1999 final-back-date=1/1/1985 mobil_average=1
                    121: 
1.296     brouard   122:   Revision 1.295  2019/05/18 09:52:50  brouard
                    123:   Summary: doxygen tex bug
                    124: 
1.295     brouard   125:   Revision 1.294  2019/05/16 14:54:33  brouard
                    126:   Summary: There was some wrong lines added
                    127: 
1.294     brouard   128:   Revision 1.293  2019/05/09 15:17:34  brouard
                    129:   *** empty log message ***
                    130: 
1.293     brouard   131:   Revision 1.292  2019/05/09 14:17:20  brouard
                    132:   Summary: Some updates
                    133: 
1.292     brouard   134:   Revision 1.291  2019/05/09 13:44:18  brouard
                    135:   Summary: Before ncovmax
                    136: 
1.291     brouard   137:   Revision 1.290  2019/05/09 13:39:37  brouard
                    138:   Summary: 0.99r18 unlimited number of individuals
                    139: 
                    140:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
                    141: 
1.290     brouard   142:   Revision 1.289  2018/12/13 09:16:26  brouard
                    143:   Summary: Bug for young ages (<-30) will be in r17
                    144: 
1.289     brouard   145:   Revision 1.288  2018/05/02 20:58:27  brouard
                    146:   Summary: Some bugs fixed
                    147: 
1.288     brouard   148:   Revision 1.287  2018/05/01 17:57:25  brouard
                    149:   Summary: Bug fixed by providing frequencies only for non missing covariates
                    150: 
1.287     brouard   151:   Revision 1.286  2018/04/27 14:27:04  brouard
                    152:   Summary: some minor bugs
                    153: 
1.286     brouard   154:   Revision 1.285  2018/04/21 21:02:16  brouard
                    155:   Summary: Some bugs fixed, valgrind tested
                    156: 
1.285     brouard   157:   Revision 1.284  2018/04/20 05:22:13  brouard
                    158:   Summary: Computing mean and stdeviation of fixed quantitative variables
                    159: 
1.284     brouard   160:   Revision 1.283  2018/04/19 14:49:16  brouard
                    161:   Summary: Some minor bugs fixed
                    162: 
1.283     brouard   163:   Revision 1.282  2018/02/27 22:50:02  brouard
                    164:   *** empty log message ***
                    165: 
1.282     brouard   166:   Revision 1.281  2018/02/27 19:25:23  brouard
                    167:   Summary: Adding second argument for quitting
                    168: 
1.281     brouard   169:   Revision 1.280  2018/02/21 07:58:13  brouard
                    170:   Summary: 0.99r15
                    171: 
                    172:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                    173: 
1.280     brouard   174:   Revision 1.279  2017/07/20 13:35:01  brouard
                    175:   Summary: temporary working
                    176: 
1.279     brouard   177:   Revision 1.278  2017/07/19 14:09:02  brouard
                    178:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                    179: 
1.278     brouard   180:   Revision 1.277  2017/07/17 08:53:49  brouard
                    181:   Summary: BOM files can be read now
                    182: 
1.277     brouard   183:   Revision 1.276  2017/06/30 15:48:31  brouard
                    184:   Summary: Graphs improvements
                    185: 
1.276     brouard   186:   Revision 1.275  2017/06/30 13:39:33  brouard
                    187:   Summary: Saito's color
                    188: 
1.275     brouard   189:   Revision 1.274  2017/06/29 09:47:08  brouard
                    190:   Summary: Version 0.99r14
                    191: 
1.274     brouard   192:   Revision 1.273  2017/06/27 11:06:02  brouard
                    193:   Summary: More documentation on projections
                    194: 
1.273     brouard   195:   Revision 1.272  2017/06/27 10:22:40  brouard
                    196:   Summary: Color of backprojection changed from 6 to 5(yellow)
                    197: 
1.272     brouard   198:   Revision 1.271  2017/06/27 10:17:50  brouard
                    199:   Summary: Some bug with rint
                    200: 
1.271     brouard   201:   Revision 1.270  2017/05/24 05:45:29  brouard
                    202:   *** empty log message ***
                    203: 
1.270     brouard   204:   Revision 1.269  2017/05/23 08:39:25  brouard
                    205:   Summary: Code into subroutine, cleanings
                    206: 
1.269     brouard   207:   Revision 1.268  2017/05/18 20:09:32  brouard
                    208:   Summary: backprojection and confidence intervals of backprevalence
                    209: 
1.268     brouard   210:   Revision 1.267  2017/05/13 10:25:05  brouard
                    211:   Summary: temporary save for backprojection
                    212: 
1.267     brouard   213:   Revision 1.266  2017/05/13 07:26:12  brouard
                    214:   Summary: Version 0.99r13 (improvements and bugs fixed)
                    215: 
1.266     brouard   216:   Revision 1.265  2017/04/26 16:22:11  brouard
                    217:   Summary: imach 0.99r13 Some bugs fixed
                    218: 
1.265     brouard   219:   Revision 1.264  2017/04/26 06:01:29  brouard
                    220:   Summary: Labels in graphs
                    221: 
1.264     brouard   222:   Revision 1.263  2017/04/24 15:23:15  brouard
                    223:   Summary: to save
                    224: 
1.263     brouard   225:   Revision 1.262  2017/04/18 16:48:12  brouard
                    226:   *** empty log message ***
                    227: 
1.262     brouard   228:   Revision 1.261  2017/04/05 10:14:09  brouard
                    229:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                    230: 
1.261     brouard   231:   Revision 1.260  2017/04/04 17:46:59  brouard
                    232:   Summary: Gnuplot indexations fixed (humm)
                    233: 
1.260     brouard   234:   Revision 1.259  2017/04/04 13:01:16  brouard
                    235:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    236: 
1.259     brouard   237:   Revision 1.258  2017/04/03 10:17:47  brouard
                    238:   Summary: Version 0.99r12
                    239: 
                    240:   Some cleanings, conformed with updated documentation.
                    241: 
1.258     brouard   242:   Revision 1.257  2017/03/29 16:53:30  brouard
                    243:   Summary: Temp
                    244: 
1.257     brouard   245:   Revision 1.256  2017/03/27 05:50:23  brouard
                    246:   Summary: Temporary
                    247: 
1.256     brouard   248:   Revision 1.255  2017/03/08 16:02:28  brouard
                    249:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    250: 
1.255     brouard   251:   Revision 1.254  2017/03/08 07:13:00  brouard
                    252:   Summary: Fixing data parameter line
                    253: 
1.254     brouard   254:   Revision 1.253  2016/12/15 11:59:41  brouard
                    255:   Summary: 0.99 in progress
                    256: 
1.253     brouard   257:   Revision 1.252  2016/09/15 21:15:37  brouard
                    258:   *** empty log message ***
                    259: 
1.252     brouard   260:   Revision 1.251  2016/09/15 15:01:13  brouard
                    261:   Summary: not working
                    262: 
1.251     brouard   263:   Revision 1.250  2016/09/08 16:07:27  brouard
                    264:   Summary: continue
                    265: 
1.250     brouard   266:   Revision 1.249  2016/09/07 17:14:18  brouard
                    267:   Summary: Starting values from frequencies
                    268: 
1.249     brouard   269:   Revision 1.248  2016/09/07 14:10:18  brouard
                    270:   *** empty log message ***
                    271: 
1.248     brouard   272:   Revision 1.247  2016/09/02 11:11:21  brouard
                    273:   *** empty log message ***
                    274: 
1.247     brouard   275:   Revision 1.246  2016/09/02 08:49:22  brouard
                    276:   *** empty log message ***
                    277: 
1.246     brouard   278:   Revision 1.245  2016/09/02 07:25:01  brouard
                    279:   *** empty log message ***
                    280: 
1.245     brouard   281:   Revision 1.244  2016/09/02 07:17:34  brouard
                    282:   *** empty log message ***
                    283: 
1.244     brouard   284:   Revision 1.243  2016/09/02 06:45:35  brouard
                    285:   *** empty log message ***
                    286: 
1.243     brouard   287:   Revision 1.242  2016/08/30 15:01:20  brouard
                    288:   Summary: Fixing a lots
                    289: 
1.242     brouard   290:   Revision 1.241  2016/08/29 17:17:25  brouard
                    291:   Summary: gnuplot problem in Back projection to fix
                    292: 
1.241     brouard   293:   Revision 1.240  2016/08/29 07:53:18  brouard
                    294:   Summary: Better
                    295: 
1.240     brouard   296:   Revision 1.239  2016/08/26 15:51:03  brouard
                    297:   Summary: Improvement in Powell output in order to copy and paste
                    298: 
                    299:   Author:
                    300: 
1.239     brouard   301:   Revision 1.238  2016/08/26 14:23:35  brouard
                    302:   Summary: Starting tests of 0.99
                    303: 
1.238     brouard   304:   Revision 1.237  2016/08/26 09:20:19  brouard
                    305:   Summary: to valgrind
                    306: 
1.237     brouard   307:   Revision 1.236  2016/08/25 10:50:18  brouard
                    308:   *** empty log message ***
                    309: 
1.236     brouard   310:   Revision 1.235  2016/08/25 06:59:23  brouard
                    311:   *** empty log message ***
                    312: 
1.235     brouard   313:   Revision 1.234  2016/08/23 16:51:20  brouard
                    314:   *** empty log message ***
                    315: 
1.234     brouard   316:   Revision 1.233  2016/08/23 07:40:50  brouard
                    317:   Summary: not working
                    318: 
1.233     brouard   319:   Revision 1.232  2016/08/22 14:20:21  brouard
                    320:   Summary: not working
                    321: 
1.232     brouard   322:   Revision 1.231  2016/08/22 07:17:15  brouard
                    323:   Summary: not working
                    324: 
1.231     brouard   325:   Revision 1.230  2016/08/22 06:55:53  brouard
                    326:   Summary: Not working
                    327: 
1.230     brouard   328:   Revision 1.229  2016/07/23 09:45:53  brouard
                    329:   Summary: Completing for func too
                    330: 
1.229     brouard   331:   Revision 1.228  2016/07/22 17:45:30  brouard
                    332:   Summary: Fixing some arrays, still debugging
                    333: 
1.227     brouard   334:   Revision 1.226  2016/07/12 18:42:34  brouard
                    335:   Summary: temp
                    336: 
1.226     brouard   337:   Revision 1.225  2016/07/12 08:40:03  brouard
                    338:   Summary: saving but not running
                    339: 
1.225     brouard   340:   Revision 1.224  2016/07/01 13:16:01  brouard
                    341:   Summary: Fixes
                    342: 
1.224     brouard   343:   Revision 1.223  2016/02/19 09:23:35  brouard
                    344:   Summary: temporary
                    345: 
1.223     brouard   346:   Revision 1.222  2016/02/17 08:14:50  brouard
                    347:   Summary: Probably last 0.98 stable version 0.98r6
                    348: 
1.222     brouard   349:   Revision 1.221  2016/02/15 23:35:36  brouard
                    350:   Summary: minor bug
                    351: 
1.220     brouard   352:   Revision 1.219  2016/02/15 00:48:12  brouard
                    353:   *** empty log message ***
                    354: 
1.219     brouard   355:   Revision 1.218  2016/02/12 11:29:23  brouard
                    356:   Summary: 0.99 Back projections
                    357: 
1.218     brouard   358:   Revision 1.217  2015/12/23 17:18:31  brouard
                    359:   Summary: Experimental backcast
                    360: 
1.217     brouard   361:   Revision 1.216  2015/12/18 17:32:11  brouard
                    362:   Summary: 0.98r4 Warning and status=-2
                    363: 
                    364:   Version 0.98r4 is now:
                    365:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    366:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    367:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    368: 
1.216     brouard   369:   Revision 1.215  2015/12/16 08:52:24  brouard
                    370:   Summary: 0.98r4 working
                    371: 
1.215     brouard   372:   Revision 1.214  2015/12/16 06:57:54  brouard
                    373:   Summary: temporary not working
                    374: 
1.214     brouard   375:   Revision 1.213  2015/12/11 18:22:17  brouard
                    376:   Summary: 0.98r4
                    377: 
1.213     brouard   378:   Revision 1.212  2015/11/21 12:47:24  brouard
                    379:   Summary: minor typo
                    380: 
1.212     brouard   381:   Revision 1.211  2015/11/21 12:41:11  brouard
                    382:   Summary: 0.98r3 with some graph of projected cross-sectional
                    383: 
                    384:   Author: Nicolas Brouard
                    385: 
1.211     brouard   386:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   387:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   388:   Summary: Adding ftolpl parameter
                    389:   Author: N Brouard
                    390: 
                    391:   We had difficulties to get smoothed confidence intervals. It was due
                    392:   to the period prevalence which wasn't computed accurately. The inner
                    393:   parameter ftolpl is now an outer parameter of the .imach parameter
                    394:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    395:   computation are long.
                    396: 
1.209     brouard   397:   Revision 1.208  2015/11/17 14:31:57  brouard
                    398:   Summary: temporary
                    399: 
1.208     brouard   400:   Revision 1.207  2015/10/27 17:36:57  brouard
                    401:   *** empty log message ***
                    402: 
1.207     brouard   403:   Revision 1.206  2015/10/24 07:14:11  brouard
                    404:   *** empty log message ***
                    405: 
1.206     brouard   406:   Revision 1.205  2015/10/23 15:50:53  brouard
                    407:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    408: 
1.205     brouard   409:   Revision 1.204  2015/10/01 16:20:26  brouard
                    410:   Summary: Some new graphs of contribution to likelihood
                    411: 
1.204     brouard   412:   Revision 1.203  2015/09/30 17:45:14  brouard
                    413:   Summary: looking at better estimation of the hessian
                    414: 
                    415:   Also a better criteria for convergence to the period prevalence And
                    416:   therefore adding the number of years needed to converge. (The
                    417:   prevalence in any alive state shold sum to one
                    418: 
1.203     brouard   419:   Revision 1.202  2015/09/22 19:45:16  brouard
                    420:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    421: 
1.202     brouard   422:   Revision 1.201  2015/09/15 17:34:58  brouard
                    423:   Summary: 0.98r0
                    424: 
                    425:   - Some new graphs like suvival functions
                    426:   - Some bugs fixed like model=1+age+V2.
                    427: 
1.201     brouard   428:   Revision 1.200  2015/09/09 16:53:55  brouard
                    429:   Summary: Big bug thanks to Flavia
                    430: 
                    431:   Even model=1+age+V2. did not work anymore
                    432: 
1.200     brouard   433:   Revision 1.199  2015/09/07 14:09:23  brouard
                    434:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    435: 
1.199     brouard   436:   Revision 1.198  2015/09/03 07:14:39  brouard
                    437:   Summary: 0.98q5 Flavia
                    438: 
1.198     brouard   439:   Revision 1.197  2015/09/01 18:24:39  brouard
                    440:   *** empty log message ***
                    441: 
1.197     brouard   442:   Revision 1.196  2015/08/18 23:17:52  brouard
                    443:   Summary: 0.98q5
                    444: 
1.196     brouard   445:   Revision 1.195  2015/08/18 16:28:39  brouard
                    446:   Summary: Adding a hack for testing purpose
                    447: 
                    448:   After reading the title, ftol and model lines, if the comment line has
                    449:   a q, starting with #q, the answer at the end of the run is quit. It
                    450:   permits to run test files in batch with ctest. The former workaround was
                    451:   $ echo q | imach foo.imach
                    452: 
1.195     brouard   453:   Revision 1.194  2015/08/18 13:32:00  brouard
                    454:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    455: 
1.194     brouard   456:   Revision 1.193  2015/08/04 07:17:42  brouard
                    457:   Summary: 0.98q4
                    458: 
1.193     brouard   459:   Revision 1.192  2015/07/16 16:49:02  brouard
                    460:   Summary: Fixing some outputs
                    461: 
1.192     brouard   462:   Revision 1.191  2015/07/14 10:00:33  brouard
                    463:   Summary: Some fixes
                    464: 
1.191     brouard   465:   Revision 1.190  2015/05/05 08:51:13  brouard
                    466:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    467: 
                    468:   Fix 1+age+.
                    469: 
1.190     brouard   470:   Revision 1.189  2015/04/30 14:45:16  brouard
                    471:   Summary: 0.98q2
                    472: 
1.189     brouard   473:   Revision 1.188  2015/04/30 08:27:53  brouard
                    474:   *** empty log message ***
                    475: 
1.188     brouard   476:   Revision 1.187  2015/04/29 09:11:15  brouard
                    477:   *** empty log message ***
                    478: 
1.187     brouard   479:   Revision 1.186  2015/04/23 12:01:52  brouard
                    480:   Summary: V1*age is working now, version 0.98q1
                    481: 
                    482:   Some codes had been disabled in order to simplify and Vn*age was
                    483:   working in the optimization phase, ie, giving correct MLE parameters,
                    484:   but, as usual, outputs were not correct and program core dumped.
                    485: 
1.186     brouard   486:   Revision 1.185  2015/03/11 13:26:42  brouard
                    487:   Summary: Inclusion of compile and links command line for Intel Compiler
                    488: 
1.185     brouard   489:   Revision 1.184  2015/03/11 11:52:39  brouard
                    490:   Summary: Back from Windows 8. Intel Compiler
                    491: 
1.184     brouard   492:   Revision 1.183  2015/03/10 20:34:32  brouard
                    493:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    494: 
                    495:   We use directest instead of original Powell test; probably no
                    496:   incidence on the results, but better justifications;
                    497:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    498:   wrong results.
                    499: 
1.183     brouard   500:   Revision 1.182  2015/02/12 08:19:57  brouard
                    501:   Summary: Trying to keep directest which seems simpler and more general
                    502:   Author: Nicolas Brouard
                    503: 
1.182     brouard   504:   Revision 1.181  2015/02/11 23:22:24  brouard
                    505:   Summary: Comments on Powell added
                    506: 
                    507:   Author:
                    508: 
1.181     brouard   509:   Revision 1.180  2015/02/11 17:33:45  brouard
                    510:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    511: 
1.180     brouard   512:   Revision 1.179  2015/01/04 09:57:06  brouard
                    513:   Summary: back to OS/X
                    514: 
1.179     brouard   515:   Revision 1.178  2015/01/04 09:35:48  brouard
                    516:   *** empty log message ***
                    517: 
1.178     brouard   518:   Revision 1.177  2015/01/03 18:40:56  brouard
                    519:   Summary: Still testing ilc32 on OSX
                    520: 
1.177     brouard   521:   Revision 1.176  2015/01/03 16:45:04  brouard
                    522:   *** empty log message ***
                    523: 
1.176     brouard   524:   Revision 1.175  2015/01/03 16:33:42  brouard
                    525:   *** empty log message ***
                    526: 
1.175     brouard   527:   Revision 1.174  2015/01/03 16:15:49  brouard
                    528:   Summary: Still in cross-compilation
                    529: 
1.174     brouard   530:   Revision 1.173  2015/01/03 12:06:26  brouard
                    531:   Summary: trying to detect cross-compilation
                    532: 
1.173     brouard   533:   Revision 1.172  2014/12/27 12:07:47  brouard
                    534:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    535: 
1.172     brouard   536:   Revision 1.171  2014/12/23 13:26:59  brouard
                    537:   Summary: Back from Visual C
                    538: 
                    539:   Still problem with utsname.h on Windows
                    540: 
1.171     brouard   541:   Revision 1.170  2014/12/23 11:17:12  brouard
                    542:   Summary: Cleaning some \%% back to %%
                    543: 
                    544:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    545: 
1.170     brouard   546:   Revision 1.169  2014/12/22 23:08:31  brouard
                    547:   Summary: 0.98p
                    548: 
                    549:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    550: 
1.169     brouard   551:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   552:   Summary: update
1.169     brouard   553: 
1.168     brouard   554:   Revision 1.167  2014/12/22 13:50:56  brouard
                    555:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    556: 
                    557:   Testing on Linux 64
                    558: 
1.167     brouard   559:   Revision 1.166  2014/12/22 11:40:47  brouard
                    560:   *** empty log message ***
                    561: 
1.166     brouard   562:   Revision 1.165  2014/12/16 11:20:36  brouard
                    563:   Summary: After compiling on Visual C
                    564: 
                    565:   * imach.c (Module): Merging 1.61 to 1.162
                    566: 
1.165     brouard   567:   Revision 1.164  2014/12/16 10:52:11  brouard
                    568:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    569: 
                    570:   * imach.c (Module): Merging 1.61 to 1.162
                    571: 
1.164     brouard   572:   Revision 1.163  2014/12/16 10:30:11  brouard
                    573:   * imach.c (Module): Merging 1.61 to 1.162
                    574: 
1.163     brouard   575:   Revision 1.162  2014/09/25 11:43:39  brouard
                    576:   Summary: temporary backup 0.99!
                    577: 
1.162     brouard   578:   Revision 1.1  2014/09/16 11:06:58  brouard
                    579:   Summary: With some code (wrong) for nlopt
                    580: 
                    581:   Author:
                    582: 
                    583:   Revision 1.161  2014/09/15 20:41:41  brouard
                    584:   Summary: Problem with macro SQR on Intel compiler
                    585: 
1.161     brouard   586:   Revision 1.160  2014/09/02 09:24:05  brouard
                    587:   *** empty log message ***
                    588: 
1.160     brouard   589:   Revision 1.159  2014/09/01 10:34:10  brouard
                    590:   Summary: WIN32
                    591:   Author: Brouard
                    592: 
1.159     brouard   593:   Revision 1.158  2014/08/27 17:11:51  brouard
                    594:   *** empty log message ***
                    595: 
1.158     brouard   596:   Revision 1.157  2014/08/27 16:26:55  brouard
                    597:   Summary: Preparing windows Visual studio version
                    598:   Author: Brouard
                    599: 
                    600:   In order to compile on Visual studio, time.h is now correct and time_t
                    601:   and tm struct should be used. difftime should be used but sometimes I
                    602:   just make the differences in raw time format (time(&now).
                    603:   Trying to suppress #ifdef LINUX
                    604:   Add xdg-open for __linux in order to open default browser.
                    605: 
1.157     brouard   606:   Revision 1.156  2014/08/25 20:10:10  brouard
                    607:   *** empty log message ***
                    608: 
1.156     brouard   609:   Revision 1.155  2014/08/25 18:32:34  brouard
                    610:   Summary: New compile, minor changes
                    611:   Author: Brouard
                    612: 
1.155     brouard   613:   Revision 1.154  2014/06/20 17:32:08  brouard
                    614:   Summary: Outputs now all graphs of convergence to period prevalence
                    615: 
1.154     brouard   616:   Revision 1.153  2014/06/20 16:45:46  brouard
                    617:   Summary: If 3 live state, convergence to period prevalence on same graph
                    618:   Author: Brouard
                    619: 
1.153     brouard   620:   Revision 1.152  2014/06/18 17:54:09  brouard
                    621:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    622: 
1.152     brouard   623:   Revision 1.151  2014/06/18 16:43:30  brouard
                    624:   *** empty log message ***
                    625: 
1.151     brouard   626:   Revision 1.150  2014/06/18 16:42:35  brouard
                    627:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    628:   Author: brouard
                    629: 
1.150     brouard   630:   Revision 1.149  2014/06/18 15:51:14  brouard
                    631:   Summary: Some fixes in parameter files errors
                    632:   Author: Nicolas Brouard
                    633: 
1.149     brouard   634:   Revision 1.148  2014/06/17 17:38:48  brouard
                    635:   Summary: Nothing new
                    636:   Author: Brouard
                    637: 
                    638:   Just a new packaging for OS/X version 0.98nS
                    639: 
1.148     brouard   640:   Revision 1.147  2014/06/16 10:33:11  brouard
                    641:   *** empty log message ***
                    642: 
1.147     brouard   643:   Revision 1.146  2014/06/16 10:20:28  brouard
                    644:   Summary: Merge
                    645:   Author: Brouard
                    646: 
                    647:   Merge, before building revised version.
                    648: 
1.146     brouard   649:   Revision 1.145  2014/06/10 21:23:15  brouard
                    650:   Summary: Debugging with valgrind
                    651:   Author: Nicolas Brouard
                    652: 
                    653:   Lot of changes in order to output the results with some covariates
                    654:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    655:   improve the code.
                    656:   No more memory valgrind error but a lot has to be done in order to
                    657:   continue the work of splitting the code into subroutines.
                    658:   Also, decodemodel has been improved. Tricode is still not
                    659:   optimal. nbcode should be improved. Documentation has been added in
                    660:   the source code.
                    661: 
1.144     brouard   662:   Revision 1.143  2014/01/26 09:45:38  brouard
                    663:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    664: 
                    665:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    666:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    667: 
1.143     brouard   668:   Revision 1.142  2014/01/26 03:57:36  brouard
                    669:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    670: 
                    671:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    672: 
1.142     brouard   673:   Revision 1.141  2014/01/26 02:42:01  brouard
                    674:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    675: 
1.141     brouard   676:   Revision 1.140  2011/09/02 10:37:54  brouard
                    677:   Summary: times.h is ok with mingw32 now.
                    678: 
1.140     brouard   679:   Revision 1.139  2010/06/14 07:50:17  brouard
                    680:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    681:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    682: 
1.139     brouard   683:   Revision 1.138  2010/04/30 18:19:40  brouard
                    684:   *** empty log message ***
                    685: 
1.138     brouard   686:   Revision 1.137  2010/04/29 18:11:38  brouard
                    687:   (Module): Checking covariates for more complex models
                    688:   than V1+V2. A lot of change to be done. Unstable.
                    689: 
1.137     brouard   690:   Revision 1.136  2010/04/26 20:30:53  brouard
                    691:   (Module): merging some libgsl code. Fixing computation
                    692:   of likelione (using inter/intrapolation if mle = 0) in order to
                    693:   get same likelihood as if mle=1.
                    694:   Some cleaning of code and comments added.
                    695: 
1.136     brouard   696:   Revision 1.135  2009/10/29 15:33:14  brouard
                    697:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    698: 
1.135     brouard   699:   Revision 1.134  2009/10/29 13:18:53  brouard
                    700:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    701: 
1.134     brouard   702:   Revision 1.133  2009/07/06 10:21:25  brouard
                    703:   just nforces
                    704: 
1.133     brouard   705:   Revision 1.132  2009/07/06 08:22:05  brouard
                    706:   Many tings
                    707: 
1.132     brouard   708:   Revision 1.131  2009/06/20 16:22:47  brouard
                    709:   Some dimensions resccaled
                    710: 
1.131     brouard   711:   Revision 1.130  2009/05/26 06:44:34  brouard
                    712:   (Module): Max Covariate is now set to 20 instead of 8. A
                    713:   lot of cleaning with variables initialized to 0. Trying to make
                    714:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    715: 
1.130     brouard   716:   Revision 1.129  2007/08/31 13:49:27  lievre
                    717:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    718: 
1.129     lievre    719:   Revision 1.128  2006/06/30 13:02:05  brouard
                    720:   (Module): Clarifications on computing e.j
                    721: 
1.128     brouard   722:   Revision 1.127  2006/04/28 18:11:50  brouard
                    723:   (Module): Yes the sum of survivors was wrong since
                    724:   imach-114 because nhstepm was no more computed in the age
                    725:   loop. Now we define nhstepma in the age loop.
                    726:   (Module): In order to speed up (in case of numerous covariates) we
                    727:   compute health expectancies (without variances) in a first step
                    728:   and then all the health expectancies with variances or standard
                    729:   deviation (needs data from the Hessian matrices) which slows the
                    730:   computation.
                    731:   In the future we should be able to stop the program is only health
                    732:   expectancies and graph are needed without standard deviations.
                    733: 
1.127     brouard   734:   Revision 1.126  2006/04/28 17:23:28  brouard
                    735:   (Module): Yes the sum of survivors was wrong since
                    736:   imach-114 because nhstepm was no more computed in the age
                    737:   loop. Now we define nhstepma in the age loop.
                    738:   Version 0.98h
                    739: 
1.126     brouard   740:   Revision 1.125  2006/04/04 15:20:31  lievre
                    741:   Errors in calculation of health expectancies. Age was not initialized.
                    742:   Forecasting file added.
                    743: 
                    744:   Revision 1.124  2006/03/22 17:13:53  lievre
                    745:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    746:   The log-likelihood is printed in the log file
                    747: 
                    748:   Revision 1.123  2006/03/20 10:52:43  brouard
                    749:   * imach.c (Module): <title> changed, corresponds to .htm file
                    750:   name. <head> headers where missing.
                    751: 
                    752:   * imach.c (Module): Weights can have a decimal point as for
                    753:   English (a comma might work with a correct LC_NUMERIC environment,
                    754:   otherwise the weight is truncated).
                    755:   Modification of warning when the covariates values are not 0 or
                    756:   1.
                    757:   Version 0.98g
                    758: 
                    759:   Revision 1.122  2006/03/20 09:45:41  brouard
                    760:   (Module): Weights can have a decimal point as for
                    761:   English (a comma might work with a correct LC_NUMERIC environment,
                    762:   otherwise the weight is truncated).
                    763:   Modification of warning when the covariates values are not 0 or
                    764:   1.
                    765:   Version 0.98g
                    766: 
                    767:   Revision 1.121  2006/03/16 17:45:01  lievre
                    768:   * imach.c (Module): Comments concerning covariates added
                    769: 
                    770:   * imach.c (Module): refinements in the computation of lli if
                    771:   status=-2 in order to have more reliable computation if stepm is
                    772:   not 1 month. Version 0.98f
                    773: 
                    774:   Revision 1.120  2006/03/16 15:10:38  lievre
                    775:   (Module): refinements in the computation of lli if
                    776:   status=-2 in order to have more reliable computation if stepm is
                    777:   not 1 month. Version 0.98f
                    778: 
                    779:   Revision 1.119  2006/03/15 17:42:26  brouard
                    780:   (Module): Bug if status = -2, the loglikelihood was
                    781:   computed as likelihood omitting the logarithm. Version O.98e
                    782: 
                    783:   Revision 1.118  2006/03/14 18:20:07  brouard
                    784:   (Module): varevsij Comments added explaining the second
                    785:   table of variances if popbased=1 .
                    786:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    787:   (Module): Function pstamp added
                    788:   (Module): Version 0.98d
                    789: 
                    790:   Revision 1.117  2006/03/14 17:16:22  brouard
                    791:   (Module): varevsij Comments added explaining the second
                    792:   table of variances if popbased=1 .
                    793:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    794:   (Module): Function pstamp added
                    795:   (Module): Version 0.98d
                    796: 
                    797:   Revision 1.116  2006/03/06 10:29:27  brouard
                    798:   (Module): Variance-covariance wrong links and
                    799:   varian-covariance of ej. is needed (Saito).
                    800: 
                    801:   Revision 1.115  2006/02/27 12:17:45  brouard
                    802:   (Module): One freematrix added in mlikeli! 0.98c
                    803: 
                    804:   Revision 1.114  2006/02/26 12:57:58  brouard
                    805:   (Module): Some improvements in processing parameter
                    806:   filename with strsep.
                    807: 
                    808:   Revision 1.113  2006/02/24 14:20:24  brouard
                    809:   (Module): Memory leaks checks with valgrind and:
                    810:   datafile was not closed, some imatrix were not freed and on matrix
                    811:   allocation too.
                    812: 
                    813:   Revision 1.112  2006/01/30 09:55:26  brouard
                    814:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    815: 
                    816:   Revision 1.111  2006/01/25 20:38:18  brouard
                    817:   (Module): Lots of cleaning and bugs added (Gompertz)
                    818:   (Module): Comments can be added in data file. Missing date values
                    819:   can be a simple dot '.'.
                    820: 
                    821:   Revision 1.110  2006/01/25 00:51:50  brouard
                    822:   (Module): Lots of cleaning and bugs added (Gompertz)
                    823: 
                    824:   Revision 1.109  2006/01/24 19:37:15  brouard
                    825:   (Module): Comments (lines starting with a #) are allowed in data.
                    826: 
                    827:   Revision 1.108  2006/01/19 18:05:42  lievre
                    828:   Gnuplot problem appeared...
                    829:   To be fixed
                    830: 
                    831:   Revision 1.107  2006/01/19 16:20:37  brouard
                    832:   Test existence of gnuplot in imach path
                    833: 
                    834:   Revision 1.106  2006/01/19 13:24:36  brouard
                    835:   Some cleaning and links added in html output
                    836: 
                    837:   Revision 1.105  2006/01/05 20:23:19  lievre
                    838:   *** empty log message ***
                    839: 
                    840:   Revision 1.104  2005/09/30 16:11:43  lievre
                    841:   (Module): sump fixed, loop imx fixed, and simplifications.
                    842:   (Module): If the status is missing at the last wave but we know
                    843:   that the person is alive, then we can code his/her status as -2
                    844:   (instead of missing=-1 in earlier versions) and his/her
                    845:   contributions to the likelihood is 1 - Prob of dying from last
                    846:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    847:   the healthy state at last known wave). Version is 0.98
                    848: 
                    849:   Revision 1.103  2005/09/30 15:54:49  lievre
                    850:   (Module): sump fixed, loop imx fixed, and simplifications.
                    851: 
                    852:   Revision 1.102  2004/09/15 17:31:30  brouard
                    853:   Add the possibility to read data file including tab characters.
                    854: 
                    855:   Revision 1.101  2004/09/15 10:38:38  brouard
                    856:   Fix on curr_time
                    857: 
                    858:   Revision 1.100  2004/07/12 18:29:06  brouard
                    859:   Add version for Mac OS X. Just define UNIX in Makefile
                    860: 
                    861:   Revision 1.99  2004/06/05 08:57:40  brouard
                    862:   *** empty log message ***
                    863: 
                    864:   Revision 1.98  2004/05/16 15:05:56  brouard
                    865:   New version 0.97 . First attempt to estimate force of mortality
                    866:   directly from the data i.e. without the need of knowing the health
                    867:   state at each age, but using a Gompertz model: log u =a + b*age .
                    868:   This is the basic analysis of mortality and should be done before any
                    869:   other analysis, in order to test if the mortality estimated from the
                    870:   cross-longitudinal survey is different from the mortality estimated
                    871:   from other sources like vital statistic data.
                    872: 
                    873:   The same imach parameter file can be used but the option for mle should be -3.
                    874: 
1.324     brouard   875:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   876:   former routines in order to include the new code within the former code.
                    877: 
                    878:   The output is very simple: only an estimate of the intercept and of
                    879:   the slope with 95% confident intervals.
                    880: 
                    881:   Current limitations:
                    882:   A) Even if you enter covariates, i.e. with the
                    883:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    884:   B) There is no computation of Life Expectancy nor Life Table.
                    885: 
                    886:   Revision 1.97  2004/02/20 13:25:42  lievre
                    887:   Version 0.96d. Population forecasting command line is (temporarily)
                    888:   suppressed.
                    889: 
                    890:   Revision 1.96  2003/07/15 15:38:55  brouard
                    891:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    892:   rewritten within the same printf. Workaround: many printfs.
                    893: 
                    894:   Revision 1.95  2003/07/08 07:54:34  brouard
                    895:   * imach.c (Repository):
                    896:   (Repository): Using imachwizard code to output a more meaningful covariance
                    897:   matrix (cov(a12,c31) instead of numbers.
                    898: 
                    899:   Revision 1.94  2003/06/27 13:00:02  brouard
                    900:   Just cleaning
                    901: 
                    902:   Revision 1.93  2003/06/25 16:33:55  brouard
                    903:   (Module): On windows (cygwin) function asctime_r doesn't
                    904:   exist so I changed back to asctime which exists.
                    905:   (Module): Version 0.96b
                    906: 
                    907:   Revision 1.92  2003/06/25 16:30:45  brouard
                    908:   (Module): On windows (cygwin) function asctime_r doesn't
                    909:   exist so I changed back to asctime which exists.
                    910: 
                    911:   Revision 1.91  2003/06/25 15:30:29  brouard
                    912:   * imach.c (Repository): Duplicated warning errors corrected.
                    913:   (Repository): Elapsed time after each iteration is now output. It
                    914:   helps to forecast when convergence will be reached. Elapsed time
                    915:   is stamped in powell.  We created a new html file for the graphs
                    916:   concerning matrix of covariance. It has extension -cov.htm.
                    917: 
                    918:   Revision 1.90  2003/06/24 12:34:15  brouard
                    919:   (Module): Some bugs corrected for windows. Also, when
                    920:   mle=-1 a template is output in file "or"mypar.txt with the design
                    921:   of the covariance matrix to be input.
                    922: 
                    923:   Revision 1.89  2003/06/24 12:30:52  brouard
                    924:   (Module): Some bugs corrected for windows. Also, when
                    925:   mle=-1 a template is output in file "or"mypar.txt with the design
                    926:   of the covariance matrix to be input.
                    927: 
                    928:   Revision 1.88  2003/06/23 17:54:56  brouard
                    929:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    930: 
                    931:   Revision 1.87  2003/06/18 12:26:01  brouard
                    932:   Version 0.96
                    933: 
                    934:   Revision 1.86  2003/06/17 20:04:08  brouard
                    935:   (Module): Change position of html and gnuplot routines and added
                    936:   routine fileappend.
                    937: 
                    938:   Revision 1.85  2003/06/17 13:12:43  brouard
                    939:   * imach.c (Repository): Check when date of death was earlier that
                    940:   current date of interview. It may happen when the death was just
                    941:   prior to the death. In this case, dh was negative and likelihood
                    942:   was wrong (infinity). We still send an "Error" but patch by
                    943:   assuming that the date of death was just one stepm after the
                    944:   interview.
                    945:   (Repository): Because some people have very long ID (first column)
                    946:   we changed int to long in num[] and we added a new lvector for
                    947:   memory allocation. But we also truncated to 8 characters (left
                    948:   truncation)
                    949:   (Repository): No more line truncation errors.
                    950: 
                    951:   Revision 1.84  2003/06/13 21:44:43  brouard
                    952:   * imach.c (Repository): Replace "freqsummary" at a correct
                    953:   place. It differs from routine "prevalence" which may be called
                    954:   many times. Probs is memory consuming and must be used with
                    955:   parcimony.
                    956:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    957: 
                    958:   Revision 1.83  2003/06/10 13:39:11  lievre
                    959:   *** empty log message ***
                    960: 
                    961:   Revision 1.82  2003/06/05 15:57:20  brouard
                    962:   Add log in  imach.c and  fullversion number is now printed.
                    963: 
                    964: */
                    965: /*
                    966:    Interpolated Markov Chain
                    967: 
                    968:   Short summary of the programme:
                    969:   
1.227     brouard   970:   This program computes Healthy Life Expectancies or State-specific
                    971:   (if states aren't health statuses) Expectancies from
                    972:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    973: 
                    974:   -1- a first survey ("cross") where individuals from different ages
                    975:   are interviewed on their health status or degree of disability (in
                    976:   the case of a health survey which is our main interest)
                    977: 
                    978:   -2- at least a second wave of interviews ("longitudinal") which
                    979:   measure each change (if any) in individual health status.  Health
                    980:   expectancies are computed from the time spent in each health state
                    981:   according to a model. More health states you consider, more time is
                    982:   necessary to reach the Maximum Likelihood of the parameters involved
                    983:   in the model.  The simplest model is the multinomial logistic model
                    984:   where pij is the probability to be observed in state j at the second
                    985:   wave conditional to be observed in state i at the first
                    986:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    987:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    988:   have a more complex model than "constant and age", you should modify
                    989:   the program where the markup *Covariates have to be included here
                    990:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   991:   convergence.
                    992: 
                    993:   The advantage of this computer programme, compared to a simple
                    994:   multinomial logistic model, is clear when the delay between waves is not
                    995:   identical for each individual. Also, if a individual missed an
                    996:   intermediate interview, the information is lost, but taken into
                    997:   account using an interpolation or extrapolation.  
                    998: 
                    999:   hPijx is the probability to be observed in state i at age x+h
                   1000:   conditional to the observed state i at age x. The delay 'h' can be
                   1001:   split into an exact number (nh*stepm) of unobserved intermediate
                   1002:   states. This elementary transition (by month, quarter,
                   1003:   semester or year) is modelled as a multinomial logistic.  The hPx
                   1004:   matrix is simply the matrix product of nh*stepm elementary matrices
                   1005:   and the contribution of each individual to the likelihood is simply
                   1006:   hPijx.
                   1007: 
                   1008:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard  1009:   of the life expectancies. It also computes the period (stable) prevalence.
                   1010: 
                   1011: Back prevalence and projections:
1.227     brouard  1012: 
                   1013:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                   1014:    double agemaxpar, double ftolpl, int *ncvyearp, double
                   1015:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                   1016:    mobilavproj)
                   1017: 
                   1018:     Computes the back prevalence limit for any combination of
                   1019:     covariate values k at any age between ageminpar and agemaxpar and
                   1020:     returns it in **bprlim. In the loops,
                   1021: 
                   1022:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                   1023:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                   1024: 
                   1025:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard  1026:    Computes for any combination of covariates k and any age between bage and fage 
                   1027:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   1028:                        oldm=oldms;savm=savms;
1.227     brouard  1029: 
1.267     brouard  1030:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard  1031:      Computes the transition matrix starting at age 'age' over
                   1032:      'nhstepm*hstepm*stepm' months (i.e. until
                   1033:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard  1034:      nhstepm*hstepm matrices. 
                   1035: 
                   1036:      Returns p3mat[i][j][h] after calling
                   1037:      p3mat[i][j][h]=matprod2(newm,
                   1038:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                   1039:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                   1040:      oldm);
1.226     brouard  1041: 
                   1042: Important routines
                   1043: 
                   1044: - func (or funcone), computes logit (pij) distinguishing
                   1045:   o fixed variables (single or product dummies or quantitative);
                   1046:   o varying variables by:
                   1047:    (1) wave (single, product dummies, quantitative), 
                   1048:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                   1049:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                   1050:        % varying dummy (not done) or quantitative (not done);
                   1051: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                   1052:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                   1053: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
1.325   ! brouard  1054:   o There are 2**cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
1.226     brouard  1055:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard  1056: 
1.226     brouard  1057: 
                   1058:   
1.324     brouard  1059:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                   1060:            Institut national d'études démographiques, Paris.
1.126     brouard  1061:   This software have been partly granted by Euro-REVES, a concerted action
                   1062:   from the European Union.
                   1063:   It is copyrighted identically to a GNU software product, ie programme and
                   1064:   software can be distributed freely for non commercial use. Latest version
                   1065:   can be accessed at http://euroreves.ined.fr/imach .
                   1066: 
                   1067:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                   1068:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                   1069:   
                   1070:   **********************************************************************/
                   1071: /*
                   1072:   main
                   1073:   read parameterfile
                   1074:   read datafile
                   1075:   concatwav
                   1076:   freqsummary
                   1077:   if (mle >= 1)
                   1078:     mlikeli
                   1079:   print results files
                   1080:   if mle==1 
                   1081:      computes hessian
                   1082:   read end of parameter file: agemin, agemax, bage, fage, estepm
                   1083:       begin-prev-date,...
                   1084:   open gnuplot file
                   1085:   open html file
1.145     brouard  1086:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                   1087:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                   1088:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                   1089:     freexexit2 possible for memory heap.
                   1090: 
                   1091:   h Pij x                         | pij_nom  ficrestpij
                   1092:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                   1093:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                   1094:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                   1095: 
                   1096:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                   1097:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                   1098:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                   1099:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                   1100:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                   1101: 
1.126     brouard  1102:   forecasting if prevfcast==1 prevforecast call prevalence()
                   1103:   health expectancies
                   1104:   Variance-covariance of DFLE
                   1105:   prevalence()
                   1106:    movingaverage()
                   1107:   varevsij() 
                   1108:   if popbased==1 varevsij(,popbased)
                   1109:   total life expectancies
                   1110:   Variance of period (stable) prevalence
                   1111:  end
                   1112: */
                   1113: 
1.187     brouard  1114: /* #define DEBUG */
                   1115: /* #define DEBUGBRENT */
1.203     brouard  1116: /* #define DEBUGLINMIN */
                   1117: /* #define DEBUGHESS */
                   1118: #define DEBUGHESSIJ
1.224     brouard  1119: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard  1120: #define POWELL /* Instead of NLOPT */
1.224     brouard  1121: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard  1122: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                   1123: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.319     brouard  1124: /* #define FLATSUP  *//* Suppresses directions where likelihood is flat */
1.126     brouard  1125: 
                   1126: #include <math.h>
                   1127: #include <stdio.h>
                   1128: #include <stdlib.h>
                   1129: #include <string.h>
1.226     brouard  1130: #include <ctype.h>
1.159     brouard  1131: 
                   1132: #ifdef _WIN32
                   1133: #include <io.h>
1.172     brouard  1134: #include <windows.h>
                   1135: #include <tchar.h>
1.159     brouard  1136: #else
1.126     brouard  1137: #include <unistd.h>
1.159     brouard  1138: #endif
1.126     brouard  1139: 
                   1140: #include <limits.h>
                   1141: #include <sys/types.h>
1.171     brouard  1142: 
                   1143: #if defined(__GNUC__)
                   1144: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1145: #endif
                   1146: 
1.126     brouard  1147: #include <sys/stat.h>
                   1148: #include <errno.h>
1.159     brouard  1149: /* extern int errno; */
1.126     brouard  1150: 
1.157     brouard  1151: /* #ifdef LINUX */
                   1152: /* #include <time.h> */
                   1153: /* #include "timeval.h" */
                   1154: /* #else */
                   1155: /* #include <sys/time.h> */
                   1156: /* #endif */
                   1157: 
1.126     brouard  1158: #include <time.h>
                   1159: 
1.136     brouard  1160: #ifdef GSL
                   1161: #include <gsl/gsl_errno.h>
                   1162: #include <gsl/gsl_multimin.h>
                   1163: #endif
                   1164: 
1.167     brouard  1165: 
1.162     brouard  1166: #ifdef NLOPT
                   1167: #include <nlopt.h>
                   1168: typedef struct {
                   1169:   double (* function)(double [] );
                   1170: } myfunc_data ;
                   1171: #endif
                   1172: 
1.126     brouard  1173: /* #include <libintl.h> */
                   1174: /* #define _(String) gettext (String) */
                   1175: 
1.251     brouard  1176: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1177: 
                   1178: #define GNUPLOTPROGRAM "gnuplot"
                   1179: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1180: #define FILENAMELENGTH 132
                   1181: 
                   1182: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1183: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1184: 
1.144     brouard  1185: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1186: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1187: 
                   1188: #define NINTERVMAX 8
1.144     brouard  1189: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1190: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.325   ! brouard  1191: #define NCOVMAX 30  /**< Maximum number of covariates used in the model, including generated covariates V1*V2 or V1*age */
1.197     brouard  1192: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1193: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1194: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1195: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1196: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1197: /* #define AGESUP 130 */
1.288     brouard  1198: /* #define AGESUP 150 */
                   1199: #define AGESUP 200
1.268     brouard  1200: #define AGEINF 0
1.218     brouard  1201: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1202: #define AGEBASE 40
1.194     brouard  1203: #define AGEOVERFLOW 1.e20
1.164     brouard  1204: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1205: #ifdef _WIN32
                   1206: #define DIRSEPARATOR '\\'
                   1207: #define CHARSEPARATOR "\\"
                   1208: #define ODIRSEPARATOR '/'
                   1209: #else
1.126     brouard  1210: #define DIRSEPARATOR '/'
                   1211: #define CHARSEPARATOR "/"
                   1212: #define ODIRSEPARATOR '\\'
                   1213: #endif
                   1214: 
1.325   ! brouard  1215: /* $Id: imach.c,v 1.324 2022/07/23 17:44:26 brouard Exp $ */
1.126     brouard  1216: /* $State: Exp $ */
1.196     brouard  1217: #include "version.h"
                   1218: char version[]=__IMACH_VERSION__;
1.323     brouard  1219: char copyright[]="July 2022,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2020, Nihon University 2021-202, INED 2000-2022";
1.325   ! brouard  1220: char fullversion[]="$Revision: 1.324 $ $Date: 2022/07/23 17:44:26 $"; 
1.126     brouard  1221: char strstart[80];
                   1222: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1223: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1224: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1225: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1226: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1227: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1228: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1229: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1230: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1231: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1232: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1233: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1234: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1235: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1236: int nsd=0; /**< Total number of single dummy variables (output) */
                   1237: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1238: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1239: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1240: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1241: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1242: int cptcov=0; /* Working variable */
1.290     brouard  1243: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1244: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.302     brouard  1245: int npar=NPARMAX; /* Number of parameters (nlstate+ndeath-1)*nlstate*ncovmodel; */
1.126     brouard  1246: int nlstate=2; /* Number of live states */
                   1247: int ndeath=1; /* Number of dead states */
1.130     brouard  1248: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1249: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1250: int popbased=0;
                   1251: 
                   1252: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1253: int maxwav=0; /* Maxim number of waves */
                   1254: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1255: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1256: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1257:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1258: int mle=1, weightopt=0;
1.126     brouard  1259: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1260: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1261: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1262:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1263: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1264: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1265: 
1.130     brouard  1266: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1267: double **matprod2(); /* test */
1.126     brouard  1268: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1269: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1270: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1271: 
1.136     brouard  1272: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1273: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1274: FILE *ficlog, *ficrespow;
1.130     brouard  1275: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1276: double fretone; /* Only one call to likelihood */
1.130     brouard  1277: long ipmx=0; /* Number of contributions */
1.126     brouard  1278: double sw; /* Sum of weights */
                   1279: char filerespow[FILENAMELENGTH];
                   1280: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1281: FILE *ficresilk;
                   1282: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1283: FILE *ficresprobmorprev;
                   1284: FILE *fichtm, *fichtmcov; /* Html File */
                   1285: FILE *ficreseij;
                   1286: char filerese[FILENAMELENGTH];
                   1287: FILE *ficresstdeij;
                   1288: char fileresstde[FILENAMELENGTH];
                   1289: FILE *ficrescveij;
                   1290: char filerescve[FILENAMELENGTH];
                   1291: FILE  *ficresvij;
                   1292: char fileresv[FILENAMELENGTH];
1.269     brouard  1293: 
1.126     brouard  1294: char title[MAXLINE];
1.234     brouard  1295: char model[MAXLINE]; /**< The model line */
1.217     brouard  1296: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1297: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1298: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1299: char command[FILENAMELENGTH];
                   1300: int  outcmd=0;
                   1301: 
1.217     brouard  1302: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1303: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1304: char filelog[FILENAMELENGTH]; /* Log file */
                   1305: char filerest[FILENAMELENGTH];
                   1306: char fileregp[FILENAMELENGTH];
                   1307: char popfile[FILENAMELENGTH];
                   1308: 
                   1309: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1310: 
1.157     brouard  1311: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1312: /* struct timezone tzp; */
                   1313: /* extern int gettimeofday(); */
                   1314: struct tm tml, *gmtime(), *localtime();
                   1315: 
                   1316: extern time_t time();
                   1317: 
                   1318: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1319: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1320: struct tm tm;
                   1321: 
1.126     brouard  1322: char strcurr[80], strfor[80];
                   1323: 
                   1324: char *endptr;
                   1325: long lval;
                   1326: double dval;
                   1327: 
                   1328: #define NR_END 1
                   1329: #define FREE_ARG char*
                   1330: #define FTOL 1.0e-10
                   1331: 
                   1332: #define NRANSI 
1.240     brouard  1333: #define ITMAX 200
                   1334: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1335: 
                   1336: #define TOL 2.0e-4 
                   1337: 
                   1338: #define CGOLD 0.3819660 
                   1339: #define ZEPS 1.0e-10 
                   1340: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1341: 
                   1342: #define GOLD 1.618034 
                   1343: #define GLIMIT 100.0 
                   1344: #define TINY 1.0e-20 
                   1345: 
                   1346: static double maxarg1,maxarg2;
                   1347: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1348: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1349:   
                   1350: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1351: #define rint(a) floor(a+0.5)
1.166     brouard  1352: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1353: #define mytinydouble 1.0e-16
1.166     brouard  1354: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1355: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1356: /* static double dsqrarg; */
                   1357: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1358: static double sqrarg;
                   1359: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1360: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1361: int agegomp= AGEGOMP;
                   1362: 
                   1363: int imx; 
                   1364: int stepm=1;
                   1365: /* Stepm, step in month: minimum step interpolation*/
                   1366: 
                   1367: int estepm;
                   1368: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1369: 
                   1370: int m,nb;
                   1371: long *num;
1.197     brouard  1372: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1373: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1374:                   covariate for which somebody answered excluding 
                   1375:                   undefined. Usually 2: 0 and 1. */
                   1376: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1377:                             covariate for which somebody answered including 
                   1378:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1379: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1380: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1381: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1382: double *ageexmed,*agecens;
                   1383: double dateintmean=0;
1.296     brouard  1384:   double anprojd, mprojd, jprojd; /* For eventual projections */
                   1385:   double anprojf, mprojf, jprojf;
1.126     brouard  1386: 
1.296     brouard  1387:   double anbackd, mbackd, jbackd; /* For eventual backprojections */
                   1388:   double anbackf, mbackf, jbackf;
                   1389:   double jintmean,mintmean,aintmean;  
1.126     brouard  1390: double *weight;
                   1391: int **s; /* Status */
1.141     brouard  1392: double *agedc;
1.145     brouard  1393: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1394:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1395:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1396: double **coqvar; /* Fixed quantitative covariate nqv */
                   1397: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1398: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1399: double  idx; 
                   1400: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.319     brouard  1401: /* Some documentation */
                   1402:       /*   Design original data
                   1403:        *  V1   V2   V3   V4  V5  V6  V7  V8  Weight ddb ddth d1st s1 V9 V10 V11 V12 s2 V9 V10 V11 V12 
                   1404:        *  <          ncovcol=6   >   nqv=2 (V7 V8)                   dv dv  dv  qtv    dv dv  dvv qtv
                   1405:        *                                                             ntv=3     nqtv=1
                   1406:        *  cptcovn number of covariates (not including constant and age) = # of + plus 1 = 10+1=11
                   1407:        * For time varying covariate, quanti or dummies
                   1408:        *       cotqvar[wav][iv(1 to nqtv)][i]= [1][12][i]=(V12) quanti
                   1409:        *       cotvar[wav][ntv+iv][i]= [3+(1 to nqtv)][i]=(V12) quanti
                   1410:        *       cotvar[wav][iv(1 to ntv)][i]= [1][1][i]=(V9) dummies at wav 1
                   1411:        *       cotvar[wav][iv(1 to ntv)][i]= [1][2][i]=(V10) dummies at wav 1
                   1412:        *       covar[k,i], value of kth fixed covariate dummy or quanti :
                   1413:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   1414:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8 + V9 + V9*age + V10
                   1415:        *   k=  1    2      3       4     5       6      7        8   9     10       11 
                   1416:        */
                   1417: /* According to the model, more columns can be added to covar by the product of covariates */
1.318     brouard  1418: /* ncovcol=1(Males=0 Females=1) nqv=1(raedyrs) ntv=2(withoutiadl=0 withiadl=1, witoutadl=0 withoutadl=1) nqtv=1(bmi) nlstate=3 ndeath=1
                   1419:   # States 1=Coresidence, 2 Living alone, 3 Institution
                   1420:   # V1=sex, V2=raedyrs Quant Fixed, State=livarnb4..livarnb11, V3=iadl4..iald11, V4=adlw4..adlw11, V5=r4bmi..r11bmi
                   1421: */
1.319     brouard  1422: /*             V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1423: /*    k        1  2   3   4     5    6    7     8    9 */
                   1424: /*Typevar[k]=  0  0   0   2     1    0    2     1    0 *//*0 for simple covariate (dummy, quantitative,*/
                   1425:                                                          /* fixed or varying), 1 for age product, 2 for*/
                   1426:                                                          /* product */
                   1427: /*Dummy[k]=    1  0   0   1     3    1    1     2    0 *//*Dummy[k] 0=dummy (0 1), 1 quantitative */
                   1428:                                                          /*(single or product without age), 2 dummy*/
                   1429:                                                          /* with age product, 3 quant with age product*/
                   1430: /*Tvar[k]=     5  4   3   6     5    2    7     1    1 */
                   1431: /*    nsd         1   2                              3 */ /* Counting single dummies covar fixed or tv */
                   1432: /*TvarsD[nsd]     4   3                              1 */ /* ID of single dummy cova fixed or timevary*/
                   1433: /*TvarsDind[k]    2   3                              9 */ /* position K of single dummy cova */
                   1434: /*    nsq      1                     2                 */ /* Counting single quantit tv */
                   1435: /* TvarsQ[k]   5                     2                 */ /* Number of single quantitative cova */
                   1436: /* TvarsQind   1                     6                 */ /* position K of single quantitative cova */
                   1437: /* Tprod[i]=k             1               2            */ /* Position in model of the ith prod without age */
                   1438: /* cptcovage                    1               2      */ /* Counting cov*age in the model equation */
                   1439: /* Tage[cptcovage]=k            5               8      */ /* Position in the model of ith cov*age */
                   1440: /* Tvard[1][1]@4={4,3,1,2}    V4*V3 V1*V2              */ /* Position in model of the ith prod without age */
                   1441: /* TvarF TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  ID of fixed covariates or product V2, V1*V2, V1 */
1.320     brouard  1442: /* TvarFind;  TvarFind[1]=6,  TvarFind[2]=7, TvarFind[3]=9 *//* Inverse V2(6) is first fixed (single or prod)  */
1.234     brouard  1443: /* Type                    */
                   1444: /* V         1  2  3  4  5 */
                   1445: /*           F  F  V  V  V */
                   1446: /*           D  Q  D  D  Q */
                   1447: /*                         */
                   1448: int *TvarsD;
                   1449: int *TvarsDind;
                   1450: int *TvarsQ;
                   1451: int *TvarsQind;
                   1452: 
1.318     brouard  1453: #define MAXRESULTLINESPONE 10+1
1.235     brouard  1454: int nresult=0;
1.258     brouard  1455: int parameterline=0; /* # of the parameter (type) line */
1.318     brouard  1456: int TKresult[MAXRESULTLINESPONE];
                   1457: int Tresult[MAXRESULTLINESPONE][NCOVMAX];/* For dummy variable , value (output) */
                   1458: int Tinvresult[MAXRESULTLINESPONE][NCOVMAX];/* For dummy variable , value (output) */
                   1459: int Tvresult[MAXRESULTLINESPONE][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1460: double Tqresult[MAXRESULTLINESPONE][NCOVMAX]; /* For quantitative variable , value (output) */
                   1461: double Tqinvresult[MAXRESULTLINESPONE][NCOVMAX]; /* For quantitative variable , value (output) */
                   1462: int Tvqresult[MAXRESULTLINESPONE][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1463: 
                   1464: /* ncovcol=1(Males=0 Females=1) nqv=1(raedyrs) ntv=2(withoutiadl=0 withiadl=1, witoutadl=0 withoutadl=1) nqtv=1(bmi) nlstate=3 ndeath=1
                   1465:   # States 1=Coresidence, 2 Living alone, 3 Institution
                   1466:   # V1=sex, V2=raedyrs Quant Fixed, State=livarnb4..livarnb11, V3=iadl4..iald11, V4=adlw4..adlw11, V5=r4bmi..r11bmi
                   1467: */
1.234     brouard  1468: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1469: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1470: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1471: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1472: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1473: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1474: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1475: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1476: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1477: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1478: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1479: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1480: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1481: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1482: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1483: 
1.230     brouard  1484: int *Tvarsel; /**< Selected covariates for output */
                   1485: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1486: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1487: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1488: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1489: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1490: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1491: int *Tage;
1.227     brouard  1492: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1493: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1494: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1495: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1496: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1497: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1498: int **Tvard;
                   1499: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1500: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1501: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1502:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1503:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1504: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1505: double *lsurv, *lpop, *tpop;
                   1506: 
1.231     brouard  1507: #define FD 1; /* Fixed dummy covariate */
                   1508: #define FQ 2; /* Fixed quantitative covariate */
                   1509: #define FP 3; /* Fixed product covariate */
                   1510: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1511: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1512: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1513: #define VD 10; /* Varying dummy covariate */
                   1514: #define VQ 11; /* Varying quantitative covariate */
                   1515: #define VP 12; /* Varying product covariate */
                   1516: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1517: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1518: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1519: #define APFD 16; /* Age product * fixed dummy covariate */
                   1520: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1521: #define APVD 18; /* Age product * varying dummy covariate */
                   1522: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1523: 
                   1524: #define FTYPE 1; /* Fixed covariate */
                   1525: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1526: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1527: 
                   1528: struct kmodel{
                   1529:        int maintype; /* main type */
                   1530:        int subtype; /* subtype */
                   1531: };
                   1532: struct kmodel modell[NCOVMAX];
                   1533: 
1.143     brouard  1534: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1535: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1536: 
                   1537: /**************** split *************************/
                   1538: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1539: {
                   1540:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1541:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1542:   */ 
                   1543:   char *ss;                            /* pointer */
1.186     brouard  1544:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1545: 
                   1546:   l1 = strlen(path );                  /* length of path */
                   1547:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1548:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1549:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1550:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1551:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1552:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1553:     /* get current working directory */
                   1554:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1555: #ifdef WIN32
                   1556:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1557: #else
                   1558:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1559: #endif
1.126     brouard  1560:       return( GLOCK_ERROR_GETCWD );
                   1561:     }
                   1562:     /* got dirc from getcwd*/
                   1563:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1564:   } else {                             /* strip directory from path */
1.126     brouard  1565:     ss++;                              /* after this, the filename */
                   1566:     l2 = strlen( ss );                 /* length of filename */
                   1567:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1568:     strcpy( name, ss );                /* save file name */
                   1569:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1570:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1571:     printf(" DIRC2 = %s \n",dirc);
                   1572:   }
                   1573:   /* We add a separator at the end of dirc if not exists */
                   1574:   l1 = strlen( dirc );                 /* length of directory */
                   1575:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1576:     dirc[l1] =  DIRSEPARATOR;
                   1577:     dirc[l1+1] = 0; 
                   1578:     printf(" DIRC3 = %s \n",dirc);
                   1579:   }
                   1580:   ss = strrchr( name, '.' );           /* find last / */
                   1581:   if (ss >0){
                   1582:     ss++;
                   1583:     strcpy(ext,ss);                    /* save extension */
                   1584:     l1= strlen( name);
                   1585:     l2= strlen(ss)+1;
                   1586:     strncpy( finame, name, l1-l2);
                   1587:     finame[l1-l2]= 0;
                   1588:   }
                   1589: 
                   1590:   return( 0 );                         /* we're done */
                   1591: }
                   1592: 
                   1593: 
                   1594: /******************************************/
                   1595: 
                   1596: void replace_back_to_slash(char *s, char*t)
                   1597: {
                   1598:   int i;
                   1599:   int lg=0;
                   1600:   i=0;
                   1601:   lg=strlen(t);
                   1602:   for(i=0; i<= lg; i++) {
                   1603:     (s[i] = t[i]);
                   1604:     if (t[i]== '\\') s[i]='/';
                   1605:   }
                   1606: }
                   1607: 
1.132     brouard  1608: char *trimbb(char *out, char *in)
1.137     brouard  1609: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1610:   char *s;
                   1611:   s=out;
                   1612:   while (*in != '\0'){
1.137     brouard  1613:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1614:       in++;
                   1615:     }
                   1616:     *out++ = *in++;
                   1617:   }
                   1618:   *out='\0';
                   1619:   return s;
                   1620: }
                   1621: 
1.187     brouard  1622: /* char *substrchaine(char *out, char *in, char *chain) */
                   1623: /* { */
                   1624: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1625: /*   char *s, *t; */
                   1626: /*   t=in;s=out; */
                   1627: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1628: /*     *out++ = *in++; */
                   1629: /*   } */
                   1630: 
                   1631: /*   /\* *in matches *chain *\/ */
                   1632: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1633: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1634: /*   } */
                   1635: /*   in--; chain--; */
                   1636: /*   while ( (*in != '\0')){ */
                   1637: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1638: /*     *out++ = *in++; */
                   1639: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1640: /*   } */
                   1641: /*   *out='\0'; */
                   1642: /*   out=s; */
                   1643: /*   return out; */
                   1644: /* } */
                   1645: char *substrchaine(char *out, char *in, char *chain)
                   1646: {
                   1647:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1648:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1649: 
                   1650:   char *strloc;
                   1651: 
                   1652:   strcpy (out, in); 
                   1653:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1654:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1655:   if(strloc != NULL){ 
                   1656:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1657:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1658:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1659:   }
                   1660:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1661:   return out;
                   1662: }
                   1663: 
                   1664: 
1.145     brouard  1665: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1666: {
1.187     brouard  1667:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1668:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.310     brouard  1669:      gives alocc="abcdef" and blocc="ghi2j".
1.145     brouard  1670:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1671:   */
1.160     brouard  1672:   char *s, *t;
1.145     brouard  1673:   t=in;s=in;
                   1674:   while ((*in != occ) && (*in != '\0')){
                   1675:     *alocc++ = *in++;
                   1676:   }
                   1677:   if( *in == occ){
                   1678:     *(alocc)='\0';
                   1679:     s=++in;
                   1680:   }
                   1681:  
                   1682:   if (s == t) {/* occ not found */
                   1683:     *(alocc-(in-s))='\0';
                   1684:     in=s;
                   1685:   }
                   1686:   while ( *in != '\0'){
                   1687:     *blocc++ = *in++;
                   1688:   }
                   1689: 
                   1690:   *blocc='\0';
                   1691:   return t;
                   1692: }
1.137     brouard  1693: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1694: {
1.187     brouard  1695:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1696:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1697:      gives blocc="abcdef2ghi" and alocc="j".
                   1698:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1699:   */
                   1700:   char *s, *t;
                   1701:   t=in;s=in;
                   1702:   while (*in != '\0'){
                   1703:     while( *in == occ){
                   1704:       *blocc++ = *in++;
                   1705:       s=in;
                   1706:     }
                   1707:     *blocc++ = *in++;
                   1708:   }
                   1709:   if (s == t) /* occ not found */
                   1710:     *(blocc-(in-s))='\0';
                   1711:   else
                   1712:     *(blocc-(in-s)-1)='\0';
                   1713:   in=s;
                   1714:   while ( *in != '\0'){
                   1715:     *alocc++ = *in++;
                   1716:   }
                   1717: 
                   1718:   *alocc='\0';
                   1719:   return s;
                   1720: }
                   1721: 
1.126     brouard  1722: int nbocc(char *s, char occ)
                   1723: {
                   1724:   int i,j=0;
                   1725:   int lg=20;
                   1726:   i=0;
                   1727:   lg=strlen(s);
                   1728:   for(i=0; i<= lg; i++) {
1.234     brouard  1729:     if  (s[i] == occ ) j++;
1.126     brouard  1730:   }
                   1731:   return j;
                   1732: }
                   1733: 
1.137     brouard  1734: /* void cutv(char *u,char *v, char*t, char occ) */
                   1735: /* { */
                   1736: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1737: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1738: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1739: /*   int i,lg,j,p=0; */
                   1740: /*   i=0; */
                   1741: /*   lg=strlen(t); */
                   1742: /*   for(j=0; j<=lg-1; j++) { */
                   1743: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1744: /*   } */
1.126     brouard  1745: 
1.137     brouard  1746: /*   for(j=0; j<p; j++) { */
                   1747: /*     (u[j] = t[j]); */
                   1748: /*   } */
                   1749: /*      u[p]='\0'; */
1.126     brouard  1750: 
1.137     brouard  1751: /*    for(j=0; j<= lg; j++) { */
                   1752: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1753: /*   } */
                   1754: /* } */
1.126     brouard  1755: 
1.160     brouard  1756: #ifdef _WIN32
                   1757: char * strsep(char **pp, const char *delim)
                   1758: {
                   1759:   char *p, *q;
                   1760:          
                   1761:   if ((p = *pp) == NULL)
                   1762:     return 0;
                   1763:   if ((q = strpbrk (p, delim)) != NULL)
                   1764:   {
                   1765:     *pp = q + 1;
                   1766:     *q = '\0';
                   1767:   }
                   1768:   else
                   1769:     *pp = 0;
                   1770:   return p;
                   1771: }
                   1772: #endif
                   1773: 
1.126     brouard  1774: /********************** nrerror ********************/
                   1775: 
                   1776: void nrerror(char error_text[])
                   1777: {
                   1778:   fprintf(stderr,"ERREUR ...\n");
                   1779:   fprintf(stderr,"%s\n",error_text);
                   1780:   exit(EXIT_FAILURE);
                   1781: }
                   1782: /*********************** vector *******************/
                   1783: double *vector(int nl, int nh)
                   1784: {
                   1785:   double *v;
                   1786:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1787:   if (!v) nrerror("allocation failure in vector");
                   1788:   return v-nl+NR_END;
                   1789: }
                   1790: 
                   1791: /************************ free vector ******************/
                   1792: void free_vector(double*v, int nl, int nh)
                   1793: {
                   1794:   free((FREE_ARG)(v+nl-NR_END));
                   1795: }
                   1796: 
                   1797: /************************ivector *******************************/
                   1798: int *ivector(long nl,long nh)
                   1799: {
                   1800:   int *v;
                   1801:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1802:   if (!v) nrerror("allocation failure in ivector");
                   1803:   return v-nl+NR_END;
                   1804: }
                   1805: 
                   1806: /******************free ivector **************************/
                   1807: void free_ivector(int *v, long nl, long nh)
                   1808: {
                   1809:   free((FREE_ARG)(v+nl-NR_END));
                   1810: }
                   1811: 
                   1812: /************************lvector *******************************/
                   1813: long *lvector(long nl,long nh)
                   1814: {
                   1815:   long *v;
                   1816:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1817:   if (!v) nrerror("allocation failure in ivector");
                   1818:   return v-nl+NR_END;
                   1819: }
                   1820: 
                   1821: /******************free lvector **************************/
                   1822: void free_lvector(long *v, long nl, long nh)
                   1823: {
                   1824:   free((FREE_ARG)(v+nl-NR_END));
                   1825: }
                   1826: 
                   1827: /******************* imatrix *******************************/
                   1828: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1829:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1830: { 
                   1831:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1832:   int **m; 
                   1833:   
                   1834:   /* allocate pointers to rows */ 
                   1835:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1836:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1837:   m += NR_END; 
                   1838:   m -= nrl; 
                   1839:   
                   1840:   
                   1841:   /* allocate rows and set pointers to them */ 
                   1842:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1843:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1844:   m[nrl] += NR_END; 
                   1845:   m[nrl] -= ncl; 
                   1846:   
                   1847:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1848:   
                   1849:   /* return pointer to array of pointers to rows */ 
                   1850:   return m; 
                   1851: } 
                   1852: 
                   1853: /****************** free_imatrix *************************/
                   1854: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1855:       int **m;
                   1856:       long nch,ncl,nrh,nrl; 
                   1857:      /* free an int matrix allocated by imatrix() */ 
                   1858: { 
                   1859:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1860:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1861: } 
                   1862: 
                   1863: /******************* matrix *******************************/
                   1864: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1865: {
                   1866:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1867:   double **m;
                   1868: 
                   1869:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1870:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1871:   m += NR_END;
                   1872:   m -= nrl;
                   1873: 
                   1874:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1875:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1876:   m[nrl] += NR_END;
                   1877:   m[nrl] -= ncl;
                   1878: 
                   1879:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1880:   return m;
1.145     brouard  1881:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1882: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1883: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1884:    */
                   1885: }
                   1886: 
                   1887: /*************************free matrix ************************/
                   1888: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1889: {
                   1890:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1891:   free((FREE_ARG)(m+nrl-NR_END));
                   1892: }
                   1893: 
                   1894: /******************* ma3x *******************************/
                   1895: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1896: {
                   1897:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1898:   double ***m;
                   1899: 
                   1900:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1901:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1902:   m += NR_END;
                   1903:   m -= nrl;
                   1904: 
                   1905:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1906:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1907:   m[nrl] += NR_END;
                   1908:   m[nrl] -= ncl;
                   1909: 
                   1910:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1911: 
                   1912:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1913:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1914:   m[nrl][ncl] += NR_END;
                   1915:   m[nrl][ncl] -= nll;
                   1916:   for (j=ncl+1; j<=nch; j++) 
                   1917:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1918:   
                   1919:   for (i=nrl+1; i<=nrh; i++) {
                   1920:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1921:     for (j=ncl+1; j<=nch; j++) 
                   1922:       m[i][j]=m[i][j-1]+nlay;
                   1923:   }
                   1924:   return m; 
                   1925:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1926:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1927:   */
                   1928: }
                   1929: 
                   1930: /*************************free ma3x ************************/
                   1931: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1932: {
                   1933:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1934:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1935:   free((FREE_ARG)(m+nrl-NR_END));
                   1936: }
                   1937: 
                   1938: /*************** function subdirf ***********/
                   1939: char *subdirf(char fileres[])
                   1940: {
                   1941:   /* Caution optionfilefiname is hidden */
                   1942:   strcpy(tmpout,optionfilefiname);
                   1943:   strcat(tmpout,"/"); /* Add to the right */
                   1944:   strcat(tmpout,fileres);
                   1945:   return tmpout;
                   1946: }
                   1947: 
                   1948: /*************** function subdirf2 ***********/
                   1949: char *subdirf2(char fileres[], char *preop)
                   1950: {
1.314     brouard  1951:   /* Example subdirf2(optionfilefiname,"FB_") with optionfilefiname="texte", result="texte/FB_texte"
                   1952:  Errors in subdirf, 2, 3 while printing tmpout is
1.315     brouard  1953:  rewritten within the same printf. Workaround: many printfs */
1.126     brouard  1954:   /* Caution optionfilefiname is hidden */
                   1955:   strcpy(tmpout,optionfilefiname);
                   1956:   strcat(tmpout,"/");
                   1957:   strcat(tmpout,preop);
                   1958:   strcat(tmpout,fileres);
                   1959:   return tmpout;
                   1960: }
                   1961: 
                   1962: /*************** function subdirf3 ***********/
                   1963: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1964: {
                   1965:   
                   1966:   /* Caution optionfilefiname is hidden */
                   1967:   strcpy(tmpout,optionfilefiname);
                   1968:   strcat(tmpout,"/");
                   1969:   strcat(tmpout,preop);
                   1970:   strcat(tmpout,preop2);
                   1971:   strcat(tmpout,fileres);
                   1972:   return tmpout;
                   1973: }
1.213     brouard  1974:  
                   1975: /*************** function subdirfext ***********/
                   1976: char *subdirfext(char fileres[], char *preop, char *postop)
                   1977: {
                   1978:   
                   1979:   strcpy(tmpout,preop);
                   1980:   strcat(tmpout,fileres);
                   1981:   strcat(tmpout,postop);
                   1982:   return tmpout;
                   1983: }
1.126     brouard  1984: 
1.213     brouard  1985: /*************** function subdirfext3 ***********/
                   1986: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1987: {
                   1988:   
                   1989:   /* Caution optionfilefiname is hidden */
                   1990:   strcpy(tmpout,optionfilefiname);
                   1991:   strcat(tmpout,"/");
                   1992:   strcat(tmpout,preop);
                   1993:   strcat(tmpout,fileres);
                   1994:   strcat(tmpout,postop);
                   1995:   return tmpout;
                   1996: }
                   1997:  
1.162     brouard  1998: char *asc_diff_time(long time_sec, char ascdiff[])
                   1999: {
                   2000:   long sec_left, days, hours, minutes;
                   2001:   days = (time_sec) / (60*60*24);
                   2002:   sec_left = (time_sec) % (60*60*24);
                   2003:   hours = (sec_left) / (60*60) ;
                   2004:   sec_left = (sec_left) %(60*60);
                   2005:   minutes = (sec_left) /60;
                   2006:   sec_left = (sec_left) % (60);
                   2007:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   2008:   return ascdiff;
                   2009: }
                   2010: 
1.126     brouard  2011: /***************** f1dim *************************/
                   2012: extern int ncom; 
                   2013: extern double *pcom,*xicom;
                   2014: extern double (*nrfunc)(double []); 
                   2015:  
                   2016: double f1dim(double x) 
                   2017: { 
                   2018:   int j; 
                   2019:   double f;
                   2020:   double *xt; 
                   2021:  
                   2022:   xt=vector(1,ncom); 
                   2023:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   2024:   f=(*nrfunc)(xt); 
                   2025:   free_vector(xt,1,ncom); 
                   2026:   return f; 
                   2027: } 
                   2028: 
                   2029: /*****************brent *************************/
                   2030: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  2031: {
                   2032:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   2033:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   2034:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   2035:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   2036:    * returned function value. 
                   2037:   */
1.126     brouard  2038:   int iter; 
                   2039:   double a,b,d,etemp;
1.159     brouard  2040:   double fu=0,fv,fw,fx;
1.164     brouard  2041:   double ftemp=0.;
1.126     brouard  2042:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   2043:   double e=0.0; 
                   2044:  
                   2045:   a=(ax < cx ? ax : cx); 
                   2046:   b=(ax > cx ? ax : cx); 
                   2047:   x=w=v=bx; 
                   2048:   fw=fv=fx=(*f)(x); 
                   2049:   for (iter=1;iter<=ITMAX;iter++) { 
                   2050:     xm=0.5*(a+b); 
                   2051:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   2052:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   2053:     printf(".");fflush(stdout);
                   2054:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  2055: #ifdef DEBUGBRENT
1.126     brouard  2056:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   2057:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   2058:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   2059: #endif
                   2060:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   2061:       *xmin=x; 
                   2062:       return fx; 
                   2063:     } 
                   2064:     ftemp=fu;
                   2065:     if (fabs(e) > tol1) { 
                   2066:       r=(x-w)*(fx-fv); 
                   2067:       q=(x-v)*(fx-fw); 
                   2068:       p=(x-v)*q-(x-w)*r; 
                   2069:       q=2.0*(q-r); 
                   2070:       if (q > 0.0) p = -p; 
                   2071:       q=fabs(q); 
                   2072:       etemp=e; 
                   2073:       e=d; 
                   2074:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  2075:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  2076:       else { 
1.224     brouard  2077:                                d=p/q; 
                   2078:                                u=x+d; 
                   2079:                                if (u-a < tol2 || b-u < tol2) 
                   2080:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  2081:       } 
                   2082:     } else { 
                   2083:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   2084:     } 
                   2085:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   2086:     fu=(*f)(u); 
                   2087:     if (fu <= fx) { 
                   2088:       if (u >= x) a=x; else b=x; 
                   2089:       SHFT(v,w,x,u) 
1.183     brouard  2090:       SHFT(fv,fw,fx,fu) 
                   2091:     } else { 
                   2092:       if (u < x) a=u; else b=u; 
                   2093:       if (fu <= fw || w == x) { 
1.224     brouard  2094:                                v=w; 
                   2095:                                w=u; 
                   2096:                                fv=fw; 
                   2097:                                fw=fu; 
1.183     brouard  2098:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  2099:                                v=u; 
                   2100:                                fv=fu; 
1.183     brouard  2101:       } 
                   2102:     } 
1.126     brouard  2103:   } 
                   2104:   nrerror("Too many iterations in brent"); 
                   2105:   *xmin=x; 
                   2106:   return fx; 
                   2107: } 
                   2108: 
                   2109: /****************** mnbrak ***********************/
                   2110: 
                   2111: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   2112:            double (*func)(double)) 
1.183     brouard  2113: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   2114: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   2115: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   2116: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   2117:    */
1.126     brouard  2118:   double ulim,u,r,q, dum;
                   2119:   double fu; 
1.187     brouard  2120: 
                   2121:   double scale=10.;
                   2122:   int iterscale=0;
                   2123: 
                   2124:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   2125:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   2126: 
                   2127: 
                   2128:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   2129:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   2130:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   2131:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   2132:   /* } */
                   2133: 
1.126     brouard  2134:   if (*fb > *fa) { 
                   2135:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  2136:     SHFT(dum,*fb,*fa,dum) 
                   2137:   } 
1.126     brouard  2138:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   2139:   *fc=(*func)(*cx); 
1.183     brouard  2140: #ifdef DEBUG
1.224     brouard  2141:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   2142:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  2143: #endif
1.224     brouard  2144:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  2145:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  2146:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  2147:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  2148:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   2149:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   2150:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  2151:       fu=(*func)(u); 
1.163     brouard  2152: #ifdef DEBUG
                   2153:       /* f(x)=A(x-u)**2+f(u) */
                   2154:       double A, fparabu; 
                   2155:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2156:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  2157:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   2158:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  2159:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   2160:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   2161:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   2162:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  2163: #endif 
1.184     brouard  2164: #ifdef MNBRAKORIGINAL
1.183     brouard  2165: #else
1.191     brouard  2166: /*       if (fu > *fc) { */
                   2167: /* #ifdef DEBUG */
                   2168: /*       printf("mnbrak4  fu > fc \n"); */
                   2169: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   2170: /* #endif */
                   2171: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   2172: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   2173: /*     dum=u; /\* Shifting c and u *\/ */
                   2174: /*     u = *cx; */
                   2175: /*     *cx = dum; */
                   2176: /*     dum = fu; */
                   2177: /*     fu = *fc; */
                   2178: /*     *fc =dum; */
                   2179: /*       } else { /\* end *\/ */
                   2180: /* #ifdef DEBUG */
                   2181: /*       printf("mnbrak3  fu < fc \n"); */
                   2182: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2183: /* #endif */
                   2184: /*     dum=u; /\* Shifting c and u *\/ */
                   2185: /*     u = *cx; */
                   2186: /*     *cx = dum; */
                   2187: /*     dum = fu; */
                   2188: /*     fu = *fc; */
                   2189: /*     *fc =dum; */
                   2190: /*       } */
1.224     brouard  2191: #ifdef DEBUGMNBRAK
                   2192:                 double A, fparabu; 
                   2193:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2194:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2195:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2196:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2197: #endif
1.191     brouard  2198:       dum=u; /* Shifting c and u */
                   2199:       u = *cx;
                   2200:       *cx = dum;
                   2201:       dum = fu;
                   2202:       fu = *fc;
                   2203:       *fc =dum;
1.183     brouard  2204: #endif
1.162     brouard  2205:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2206: #ifdef DEBUG
1.224     brouard  2207:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2208:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2209: #endif
1.126     brouard  2210:       fu=(*func)(u); 
                   2211:       if (fu < *fc) { 
1.183     brouard  2212: #ifdef DEBUG
1.224     brouard  2213:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2214:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2215: #endif
                   2216:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2217:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2218: #ifdef DEBUG
                   2219:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2220: #endif
                   2221:       } 
1.162     brouard  2222:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2223: #ifdef DEBUG
1.224     brouard  2224:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2225:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2226: #endif
1.126     brouard  2227:       u=ulim; 
                   2228:       fu=(*func)(u); 
1.183     brouard  2229:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2230: #ifdef DEBUG
1.224     brouard  2231:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2232:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2233: #endif
1.126     brouard  2234:       u=(*cx)+GOLD*(*cx-*bx); 
                   2235:       fu=(*func)(u); 
1.224     brouard  2236: #ifdef DEBUG
                   2237:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2238:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2239: #endif
1.183     brouard  2240:     } /* end tests */
1.126     brouard  2241:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2242:     SHFT(*fa,*fb,*fc,fu) 
                   2243: #ifdef DEBUG
1.224     brouard  2244:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2245:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2246: #endif
                   2247:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2248: } 
                   2249: 
                   2250: /*************** linmin ************************/
1.162     brouard  2251: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2252: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2253: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2254: the value of func at the returned location p . This is actually all accomplished by calling the
                   2255: routines mnbrak and brent .*/
1.126     brouard  2256: int ncom; 
                   2257: double *pcom,*xicom;
                   2258: double (*nrfunc)(double []); 
                   2259:  
1.224     brouard  2260: #ifdef LINMINORIGINAL
1.126     brouard  2261: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2262: #else
                   2263: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2264: #endif
1.126     brouard  2265: { 
                   2266:   double brent(double ax, double bx, double cx, 
                   2267:               double (*f)(double), double tol, double *xmin); 
                   2268:   double f1dim(double x); 
                   2269:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2270:              double *fc, double (*func)(double)); 
                   2271:   int j; 
                   2272:   double xx,xmin,bx,ax; 
                   2273:   double fx,fb,fa;
1.187     brouard  2274: 
1.203     brouard  2275: #ifdef LINMINORIGINAL
                   2276: #else
                   2277:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2278: #endif
                   2279:   
1.126     brouard  2280:   ncom=n; 
                   2281:   pcom=vector(1,n); 
                   2282:   xicom=vector(1,n); 
                   2283:   nrfunc=func; 
                   2284:   for (j=1;j<=n;j++) { 
                   2285:     pcom[j]=p[j]; 
1.202     brouard  2286:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2287:   } 
1.187     brouard  2288: 
1.203     brouard  2289: #ifdef LINMINORIGINAL
                   2290:   xx=1.;
                   2291: #else
                   2292:   axs=0.0;
                   2293:   xxs=1.;
                   2294:   do{
                   2295:     xx= xxs;
                   2296: #endif
1.187     brouard  2297:     ax=0.;
                   2298:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2299:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2300:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2301:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2302:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2303:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2304:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2305: #ifdef LINMINORIGINAL
                   2306: #else
                   2307:     if (fx != fx){
1.224     brouard  2308:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2309:                        printf("|");
                   2310:                        fprintf(ficlog,"|");
1.203     brouard  2311: #ifdef DEBUGLINMIN
1.224     brouard  2312:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2313: #endif
                   2314:     }
1.224     brouard  2315:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2316: #endif
                   2317:   
1.191     brouard  2318: #ifdef DEBUGLINMIN
                   2319:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2320:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2321: #endif
1.224     brouard  2322: #ifdef LINMINORIGINAL
                   2323: #else
1.317     brouard  2324:   if(fb == fx){ /* Flat function in the direction */
                   2325:     xmin=xx;
1.224     brouard  2326:     *flat=1;
1.317     brouard  2327:   }else{
1.224     brouard  2328:     *flat=0;
                   2329: #endif
                   2330:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2331:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2332:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2333:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2334:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2335:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2336: #ifdef DEBUG
1.224     brouard  2337:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2338:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2339: #endif
                   2340: #ifdef LINMINORIGINAL
                   2341: #else
                   2342:                        }
1.126     brouard  2343: #endif
1.191     brouard  2344: #ifdef DEBUGLINMIN
                   2345:   printf("linmin end ");
1.202     brouard  2346:   fprintf(ficlog,"linmin end ");
1.191     brouard  2347: #endif
1.126     brouard  2348:   for (j=1;j<=n;j++) { 
1.203     brouard  2349: #ifdef LINMINORIGINAL
                   2350:     xi[j] *= xmin; 
                   2351: #else
                   2352: #ifdef DEBUGLINMIN
                   2353:     if(xxs <1.0)
                   2354:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2355: #endif
                   2356:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2357: #ifdef DEBUGLINMIN
                   2358:     if(xxs <1.0)
                   2359:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2360: #endif
                   2361: #endif
1.187     brouard  2362:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2363:   } 
1.191     brouard  2364: #ifdef DEBUGLINMIN
1.203     brouard  2365:   printf("\n");
1.191     brouard  2366:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2367:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2368:   for (j=1;j<=n;j++) { 
1.202     brouard  2369:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2370:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2371:     if(j % ncovmodel == 0){
1.191     brouard  2372:       printf("\n");
1.202     brouard  2373:       fprintf(ficlog,"\n");
                   2374:     }
1.191     brouard  2375:   }
1.203     brouard  2376: #else
1.191     brouard  2377: #endif
1.126     brouard  2378:   free_vector(xicom,1,n); 
                   2379:   free_vector(pcom,1,n); 
                   2380: } 
                   2381: 
                   2382: 
                   2383: /*************** powell ************************/
1.162     brouard  2384: /*
1.317     brouard  2385: Minimization of a function func of n variables. Input consists in an initial starting point
                   2386: p[1..n] ; an initial matrix xi[1..n][1..n]  whose columns contain the initial set of di-
                   2387: rections (usually the n unit vectors); and ftol, the fractional tolerance in the function value
                   2388: such that failure to decrease by more than this amount in one iteration signals doneness. On
1.162     brouard  2389: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2390: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2391:  */
1.224     brouard  2392: #ifdef LINMINORIGINAL
                   2393: #else
                   2394:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2395:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2396: #endif
1.126     brouard  2397: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2398:            double (*func)(double [])) 
                   2399: { 
1.224     brouard  2400: #ifdef LINMINORIGINAL
                   2401:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2402:              double (*func)(double [])); 
1.224     brouard  2403: #else 
1.241     brouard  2404:  void linmin(double p[], double xi[], int n, double *fret,
                   2405:             double (*func)(double []),int *flat); 
1.224     brouard  2406: #endif
1.239     brouard  2407:  int i,ibig,j,jk,k; 
1.126     brouard  2408:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2409:   double directest;
1.126     brouard  2410:   double fp,fptt;
                   2411:   double *xits;
                   2412:   int niterf, itmp;
                   2413: 
                   2414:   pt=vector(1,n); 
                   2415:   ptt=vector(1,n); 
                   2416:   xit=vector(1,n); 
                   2417:   xits=vector(1,n); 
                   2418:   *fret=(*func)(p); 
                   2419:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2420:   rcurr_time = time(NULL);  
1.126     brouard  2421:   for (*iter=1;;++(*iter)) { 
                   2422:     ibig=0; 
                   2423:     del=0.0; 
1.157     brouard  2424:     rlast_time=rcurr_time;
                   2425:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2426:     rcurr_time = time(NULL);  
                   2427:     curr_time = *localtime(&rcurr_time);
1.324     brouard  2428:     printf("\nPowell iter=%d -2*LL=%.12f gain=%.12f=%.3g %ld sec. %ld sec.",*iter,*fret, fp-*fret,fp-*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2429:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f gain=%.12f=%.3g %ld sec. %ld sec.",*iter,*fret, fp-*fret,fp-*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
1.157     brouard  2430: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.324     brouard  2431:     fp=(*fret); /* From former iteration or initial value */
1.192     brouard  2432:     for (i=1;i<=n;i++) {
1.126     brouard  2433:       fprintf(ficrespow," %.12lf", p[i]);
                   2434:     }
1.239     brouard  2435:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2436:     printf("\n#model=  1      +     age ");
                   2437:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2438:     if(nagesqr==1){
1.241     brouard  2439:        printf("  + age*age  ");
                   2440:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2441:     }
                   2442:     for(j=1;j <=ncovmodel-2;j++){
                   2443:       if(Typevar[j]==0) {
                   2444:        printf("  +      V%d  ",Tvar[j]);
                   2445:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2446:       }else if(Typevar[j]==1) {
                   2447:        printf("  +    V%d*age ",Tvar[j]);
                   2448:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2449:       }else if(Typevar[j]==2) {
                   2450:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2451:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2452:       }
                   2453:     }
1.126     brouard  2454:     printf("\n");
1.239     brouard  2455: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2456: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2457:     fprintf(ficlog,"\n");
1.239     brouard  2458:     for(i=1,jk=1; i <=nlstate; i++){
                   2459:       for(k=1; k <=(nlstate+ndeath); k++){
                   2460:        if (k != i) {
                   2461:          printf("%d%d ",i,k);
                   2462:          fprintf(ficlog,"%d%d ",i,k);
                   2463:          for(j=1; j <=ncovmodel; j++){
                   2464:            printf("%12.7f ",p[jk]);
                   2465:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2466:            jk++; 
                   2467:          }
                   2468:          printf("\n");
                   2469:          fprintf(ficlog,"\n");
                   2470:        }
                   2471:       }
                   2472:     }
1.241     brouard  2473:     if(*iter <=3 && *iter >1){
1.157     brouard  2474:       tml = *localtime(&rcurr_time);
                   2475:       strcpy(strcurr,asctime(&tml));
                   2476:       rforecast_time=rcurr_time; 
1.126     brouard  2477:       itmp = strlen(strcurr);
                   2478:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2479:        strcurr[itmp-1]='\0';
1.162     brouard  2480:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2481:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2482:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2483:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2484:        forecast_time = *localtime(&rforecast_time);
                   2485:        strcpy(strfor,asctime(&forecast_time));
                   2486:        itmp = strlen(strfor);
                   2487:        if(strfor[itmp-1]=='\n')
                   2488:          strfor[itmp-1]='\0';
                   2489:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2490:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2491:       }
                   2492:     }
1.187     brouard  2493:     for (i=1;i<=n;i++) { /* For each direction i */
                   2494:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2495:       fptt=(*fret); 
                   2496: #ifdef DEBUG
1.203     brouard  2497:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2498:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2499: #endif
1.203     brouard  2500:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2501:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2502: #ifdef LINMINORIGINAL
1.188     brouard  2503:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2504: #else
                   2505:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2506:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2507: #endif
                   2508:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2509:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2510:                                /* because that direction will be replaced unless the gain del is small */
                   2511:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2512:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2513:                                /* with the new direction. */
                   2514:                                del=fabs(fptt-(*fret)); 
                   2515:                                ibig=i; 
1.126     brouard  2516:       } 
                   2517: #ifdef DEBUG
                   2518:       printf("%d %.12e",i,(*fret));
                   2519:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2520:       for (j=1;j<=n;j++) {
1.224     brouard  2521:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2522:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2523:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2524:       }
                   2525:       for(j=1;j<=n;j++) {
1.225     brouard  2526:                                printf(" p(%d)=%.12e",j,p[j]);
                   2527:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2528:       }
                   2529:       printf("\n");
                   2530:       fprintf(ficlog,"\n");
                   2531: #endif
1.187     brouard  2532:     } /* end loop on each direction i */
                   2533:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2534:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2535:     /* New value of last point Pn is not computed, P(n-1) */
1.319     brouard  2536:     for(j=1;j<=n;j++) {
                   2537:       if(flatdir[j] >0){
                   2538:         printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2539:         fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
1.302     brouard  2540:       }
1.319     brouard  2541:       /* printf("\n"); */
                   2542:       /* fprintf(ficlog,"\n"); */
                   2543:     }
1.243     brouard  2544:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2545:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2546:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2547:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2548:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2549:       /* decreased of more than 3.84  */
                   2550:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2551:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2552:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2553:                        
1.188     brouard  2554:       /* Starting the program with initial values given by a former maximization will simply change */
                   2555:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2556:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2557:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2558: #ifdef DEBUG
                   2559:       int k[2],l;
                   2560:       k[0]=1;
                   2561:       k[1]=-1;
                   2562:       printf("Max: %.12e",(*func)(p));
                   2563:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2564:       for (j=1;j<=n;j++) {
                   2565:        printf(" %.12e",p[j]);
                   2566:        fprintf(ficlog," %.12e",p[j]);
                   2567:       }
                   2568:       printf("\n");
                   2569:       fprintf(ficlog,"\n");
                   2570:       for(l=0;l<=1;l++) {
                   2571:        for (j=1;j<=n;j++) {
                   2572:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2573:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2574:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2575:        }
                   2576:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2577:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2578:       }
                   2579: #endif
                   2580: 
                   2581:       free_vector(xit,1,n); 
                   2582:       free_vector(xits,1,n); 
                   2583:       free_vector(ptt,1,n); 
                   2584:       free_vector(pt,1,n); 
                   2585:       return; 
1.192     brouard  2586:     } /* enough precision */ 
1.240     brouard  2587:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2588:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2589:       ptt[j]=2.0*p[j]-pt[j]; 
                   2590:       xit[j]=p[j]-pt[j]; 
                   2591:       pt[j]=p[j]; 
                   2592:     } 
1.181     brouard  2593:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2594: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2595:                if (*iter <=4) {
1.225     brouard  2596: #else
                   2597: #endif
1.224     brouard  2598: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2599: #else
1.161     brouard  2600:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2601: #endif
1.162     brouard  2602:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2603:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2604:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2605:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2606:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2607:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2608:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2609:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2610:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2611:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2612:       /* mu² and del² are equal when f3=f1 */
                   2613:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2614:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2615:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2616:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2617: #ifdef NRCORIGINAL
                   2618:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2619: #else
                   2620:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2621:       t= t- del*SQR(fp-fptt);
1.183     brouard  2622: #endif
1.202     brouard  2623:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2624: #ifdef DEBUG
1.181     brouard  2625:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2626:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2627:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2628:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2629:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2630:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2631:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2632:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2633: #endif
1.183     brouard  2634: #ifdef POWELLORIGINAL
                   2635:       if (t < 0.0) { /* Then we use it for new direction */
                   2636: #else
1.182     brouard  2637:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2638:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2639:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2640:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2641:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2642:       } 
1.181     brouard  2643:       if (directest < 0.0) { /* Then we use it for new direction */
                   2644: #endif
1.191     brouard  2645: #ifdef DEBUGLINMIN
1.234     brouard  2646:        printf("Before linmin in direction P%d-P0\n",n);
                   2647:        for (j=1;j<=n;j++) {
                   2648:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2649:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2650:          if(j % ncovmodel == 0){
                   2651:            printf("\n");
                   2652:            fprintf(ficlog,"\n");
                   2653:          }
                   2654:        }
1.224     brouard  2655: #endif
                   2656: #ifdef LINMINORIGINAL
1.234     brouard  2657:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2658: #else
1.234     brouard  2659:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2660:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2661: #endif
1.234     brouard  2662:        
1.191     brouard  2663: #ifdef DEBUGLINMIN
1.234     brouard  2664:        for (j=1;j<=n;j++) { 
                   2665:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2666:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2667:          if(j % ncovmodel == 0){
                   2668:            printf("\n");
                   2669:            fprintf(ficlog,"\n");
                   2670:          }
                   2671:        }
1.224     brouard  2672: #endif
1.234     brouard  2673:        for (j=1;j<=n;j++) { 
                   2674:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2675:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2676:        }
1.224     brouard  2677: #ifdef LINMINORIGINAL
                   2678: #else
1.234     brouard  2679:        for (j=1, flatd=0;j<=n;j++) {
                   2680:          if(flatdir[j]>0)
                   2681:            flatd++;
                   2682:        }
                   2683:        if(flatd >0){
1.255     brouard  2684:          printf("%d flat directions: ",flatd);
                   2685:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2686:          for (j=1;j<=n;j++) { 
                   2687:            if(flatdir[j]>0){
                   2688:              printf("%d ",j);
                   2689:              fprintf(ficlog,"%d ",j);
                   2690:            }
                   2691:          }
                   2692:          printf("\n");
                   2693:          fprintf(ficlog,"\n");
1.319     brouard  2694: #ifdef FLATSUP
                   2695:           free_vector(xit,1,n); 
                   2696:           free_vector(xits,1,n); 
                   2697:           free_vector(ptt,1,n); 
                   2698:           free_vector(pt,1,n); 
                   2699:           return;
                   2700: #endif
1.234     brouard  2701:        }
1.191     brouard  2702: #endif
1.234     brouard  2703:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2704:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2705:        
1.126     brouard  2706: #ifdef DEBUG
1.234     brouard  2707:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2708:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2709:        for(j=1;j<=n;j++){
                   2710:          printf(" %lf",xit[j]);
                   2711:          fprintf(ficlog," %lf",xit[j]);
                   2712:        }
                   2713:        printf("\n");
                   2714:        fprintf(ficlog,"\n");
1.126     brouard  2715: #endif
1.192     brouard  2716:       } /* end of t or directest negative */
1.224     brouard  2717: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2718: #else
1.234     brouard  2719:       } /* end if (fptt < fp)  */
1.192     brouard  2720: #endif
1.225     brouard  2721: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2722:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2723: #else
1.224     brouard  2724: #endif
1.234     brouard  2725:                } /* loop iteration */ 
1.126     brouard  2726: } 
1.234     brouard  2727:   
1.126     brouard  2728: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2729:   
1.235     brouard  2730:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2731:   {
1.279     brouard  2732:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2733:      *   (and selected quantitative values in nres)
                   2734:      *  by left multiplying the unit
                   2735:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2736:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2737:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2738:      * or prevalence in state 1, prevalence in state 2, 0
                   2739:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2740:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2741:      * Output is prlim.
                   2742:      * Initial matrix pimij 
                   2743:      */
1.206     brouard  2744:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2745:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2746:   /*  0,                   0                  , 1} */
                   2747:   /*
                   2748:    * and after some iteration: */
                   2749:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2750:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2751:   /*  0,                   0                  , 1} */
                   2752:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2753:   /* {0.51571254859325999, 0.4842874514067399, */
                   2754:   /*  0.51326036147820708, 0.48673963852179264} */
                   2755:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2756:     
1.126     brouard  2757:   int i, ii,j,k;
1.209     brouard  2758:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2759:   /* double **matprod2(); */ /* test */
1.218     brouard  2760:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2761:   double **newm;
1.209     brouard  2762:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2763:   int ncvloop=0;
1.288     brouard  2764:   int first=0;
1.169     brouard  2765:   
1.209     brouard  2766:   min=vector(1,nlstate);
                   2767:   max=vector(1,nlstate);
                   2768:   meandiff=vector(1,nlstate);
                   2769: 
1.218     brouard  2770:        /* Starting with matrix unity */
1.126     brouard  2771:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2772:     for (j=1;j<=nlstate+ndeath;j++){
                   2773:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2774:     }
1.169     brouard  2775:   
                   2776:   cov[1]=1.;
                   2777:   
                   2778:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2779:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2780:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2781:     ncvloop++;
1.126     brouard  2782:     newm=savm;
                   2783:     /* Covariates have to be included here again */
1.138     brouard  2784:     cov[2]=agefin;
1.319     brouard  2785:      if(nagesqr==1){
                   2786:       cov[3]= agefin*agefin;
                   2787:      }
1.234     brouard  2788:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2789:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2790:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.319     brouard  2791:       /* cov[++k1]=nbcode[TvarsD[k]][codtabm(ij,k)]; */
1.235     brouard  2792:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2793:     }
                   2794:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2795:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.319     brouard  2796:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k];
                   2797:       /* cov[++k1]=Tqresult[nres][k];  */
1.235     brouard  2798:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2799:     }
1.237     brouard  2800:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.319     brouard  2801:       if(Dummy[Tage[k]]==2){ /* dummy with age */
1.234     brouard  2802:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319     brouard  2803:        /* cov[++k1]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   2804:       } else if(Dummy[Tage[k]]==3){ /* quantitative with age */
                   2805:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k];
                   2806:        /* cov[++k1]=Tqresult[nres][k];  */
1.234     brouard  2807:       }
1.235     brouard  2808:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2809:     }
1.237     brouard  2810:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2811:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2812:       if(Dummy[Tvard[k][1]==0]){
                   2813:        if(Dummy[Tvard[k][2]==0]){
                   2814:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
1.319     brouard  2815:          /* cov[++k1]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.237     brouard  2816:        }else{
                   2817:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
1.319     brouard  2818:          /* cov[++k1]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k]; */
1.237     brouard  2819:        }
                   2820:       }else{
                   2821:        if(Dummy[Tvard[k][2]==0]){
                   2822:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
1.319     brouard  2823:          /* cov[++k1]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]]; */
1.237     brouard  2824:        }else{
                   2825:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
1.319     brouard  2826:          /* cov[++k1]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]]; */
1.237     brouard  2827:        }
                   2828:       }
1.234     brouard  2829:     }
1.138     brouard  2830:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2831:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2832:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2833:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2834:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.319     brouard  2835:     /* age and covariate values of ij are in 'cov' */
1.142     brouard  2836:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2837:     
1.126     brouard  2838:     savm=oldm;
                   2839:     oldm=newm;
1.209     brouard  2840: 
                   2841:     for(j=1; j<=nlstate; j++){
                   2842:       max[j]=0.;
                   2843:       min[j]=1.;
                   2844:     }
                   2845:     for(i=1;i<=nlstate;i++){
                   2846:       sumnew=0;
                   2847:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2848:       for(j=1; j<=nlstate; j++){ 
                   2849:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2850:        max[j]=FMAX(max[j],prlim[i][j]);
                   2851:        min[j]=FMIN(min[j],prlim[i][j]);
                   2852:       }
                   2853:     }
                   2854: 
1.126     brouard  2855:     maxmax=0.;
1.209     brouard  2856:     for(j=1; j<=nlstate; j++){
                   2857:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2858:       maxmax=FMAX(maxmax,meandiff[j]);
                   2859:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2860:     } /* j loop */
1.203     brouard  2861:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2862:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2863:     if(maxmax < ftolpl){
1.209     brouard  2864:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2865:       free_vector(min,1,nlstate);
                   2866:       free_vector(max,1,nlstate);
                   2867:       free_vector(meandiff,1,nlstate);
1.126     brouard  2868:       return prlim;
                   2869:     }
1.288     brouard  2870:   } /* agefin loop */
1.208     brouard  2871:     /* After some age loop it doesn't converge */
1.288     brouard  2872:   if(!first){
                   2873:     first=1;
                   2874:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
1.317     brouard  2875:     fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2876:   }else if (first >=1 && first <10){
                   2877:     fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2878:     first++;
                   2879:   }else if (first ==10){
                   2880:     fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2881:     printf("Warning: the stable prevalence dit not converge. This warning came too often, IMaCh will stop notifying, even in its log file. Look at the graphs to appreciate the non convergence.\n");
                   2882:     fprintf(ficlog,"Warning: the stable prevalence no convergence; too many cases, giving up noticing, even in log file\n");
                   2883:     first++;
1.288     brouard  2884:   }
                   2885: 
1.209     brouard  2886:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2887:   free_vector(min,1,nlstate);
                   2888:   free_vector(max,1,nlstate);
                   2889:   free_vector(meandiff,1,nlstate);
1.208     brouard  2890:   
1.169     brouard  2891:   return prlim; /* should not reach here */
1.126     brouard  2892: }
                   2893: 
1.217     brouard  2894: 
                   2895:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2896: 
1.218     brouard  2897:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2898:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2899:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2900: {
1.264     brouard  2901:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2902:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2903:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2904:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2905:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2906:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2907:   /* Initial matrix pimij */
                   2908:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2909:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2910:   /*  0,                   0                  , 1} */
                   2911:   /*
                   2912:    * and after some iteration: */
                   2913:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2914:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2915:   /*  0,                   0                  , 1} */
                   2916:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2917:   /* {0.51571254859325999, 0.4842874514067399, */
                   2918:   /*  0.51326036147820708, 0.48673963852179264} */
                   2919:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2920: 
                   2921:   int i, ii,j,k;
1.247     brouard  2922:   int first=0;
1.217     brouard  2923:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2924:   /* double **matprod2(); */ /* test */
                   2925:   double **out, cov[NCOVMAX+1], **bmij();
                   2926:   double **newm;
1.218     brouard  2927:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2928:   double        **oldm, **savm;  /* for use */
                   2929: 
1.217     brouard  2930:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2931:   int ncvloop=0;
                   2932:   
                   2933:   min=vector(1,nlstate);
                   2934:   max=vector(1,nlstate);
                   2935:   meandiff=vector(1,nlstate);
                   2936: 
1.266     brouard  2937:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2938:   oldm=oldms; savm=savms;
                   2939:   
                   2940:   /* Starting with matrix unity */
                   2941:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2942:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2943:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2944:     }
                   2945:   
                   2946:   cov[1]=1.;
                   2947:   
                   2948:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2949:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2950:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2951:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2952:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2953:     ncvloop++;
1.218     brouard  2954:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2955:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2956:     /* Covariates have to be included here again */
                   2957:     cov[2]=agefin;
1.319     brouard  2958:     if(nagesqr==1){
1.217     brouard  2959:       cov[3]= agefin*agefin;;
1.319     brouard  2960:     }
1.242     brouard  2961:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2962:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2963:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2964:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2965:     }
                   2966:     /* for (k=1; k<=cptcovn;k++) { */
                   2967:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2968:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2969:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2970:     /* } */
                   2971:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2972:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2973:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2974:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2975:     }
                   2976:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2977:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2978:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2979:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2980:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.319     brouard  2981:       /* if(Dummy[Tvar[Tage[k]]]== 2){ /\* dummy with age *\/ ERROR ???*/
                   2982:       if(Dummy[Tage[k]]== 2){ /* dummy with age */
1.242     brouard  2983:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319     brouard  2984:       } else if(Dummy[Tage[k]]== 3){ /* quantitative with age */
                   2985:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k];
1.242     brouard  2986:       }
                   2987:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2988:     }
                   2989:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2990:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2991:       if(Dummy[Tvard[k][1]==0]){
                   2992:        if(Dummy[Tvard[k][2]==0]){
                   2993:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2994:        }else{
                   2995:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2996:        }
                   2997:       }else{
                   2998:        if(Dummy[Tvard[k][2]==0]){
                   2999:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   3000:        }else{
                   3001:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   3002:        }
                   3003:       }
1.217     brouard  3004:     }
                   3005:     
                   3006:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   3007:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   3008:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   3009:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3010:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  3011:                /* ij should be linked to the correct index of cov */
                   3012:                /* age and covariate values ij are in 'cov', but we need to pass
                   3013:                 * ij for the observed prevalence at age and status and covariate
                   3014:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   3015:                 */
                   3016:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   3017:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   3018:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  3019:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  3020:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   3021:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   3022:     /*         printf("%d newm= ",i); */
                   3023:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3024:     /*           printf("%f ",newm[i][j]); */
                   3025:     /*         } */
                   3026:     /*         printf("oldm * "); */
                   3027:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3028:     /*           printf("%f ",oldm[i][j]); */
                   3029:     /*         } */
1.268     brouard  3030:     /*         printf(" bmmij "); */
1.266     brouard  3031:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3032:     /*           printf("%f ",pmmij[i][j]); */
                   3033:     /*         } */
                   3034:     /*         printf("\n"); */
                   3035:     /*   } */
                   3036:     /* } */
1.217     brouard  3037:     savm=oldm;
                   3038:     oldm=newm;
1.266     brouard  3039: 
1.217     brouard  3040:     for(j=1; j<=nlstate; j++){
                   3041:       max[j]=0.;
                   3042:       min[j]=1.;
                   3043:     }
                   3044:     for(j=1; j<=nlstate; j++){ 
                   3045:       for(i=1;i<=nlstate;i++){
1.234     brouard  3046:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   3047:        bprlim[i][j]= newm[i][j];
                   3048:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   3049:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  3050:       }
                   3051:     }
1.218     brouard  3052:                
1.217     brouard  3053:     maxmax=0.;
                   3054:     for(i=1; i<=nlstate; i++){
1.318     brouard  3055:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column, could be nan! */
1.217     brouard  3056:       maxmax=FMAX(maxmax,meandiff[i]);
                   3057:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  3058:     } /* i loop */
1.217     brouard  3059:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  3060:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  3061:     if(maxmax < ftolpl){
1.220     brouard  3062:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  3063:       free_vector(min,1,nlstate);
                   3064:       free_vector(max,1,nlstate);
                   3065:       free_vector(meandiff,1,nlstate);
                   3066:       return bprlim;
                   3067:     }
1.288     brouard  3068:   } /* agefin loop */
1.217     brouard  3069:     /* After some age loop it doesn't converge */
1.288     brouard  3070:   if(!first){
1.247     brouard  3071:     first=1;
                   3072:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   3073: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   3074:   }
                   3075:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  3076: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   3077:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   3078:   free_vector(min,1,nlstate);
                   3079:   free_vector(max,1,nlstate);
                   3080:   free_vector(meandiff,1,nlstate);
                   3081:   
                   3082:   return bprlim; /* should not reach here */
                   3083: }
                   3084: 
1.126     brouard  3085: /*************** transition probabilities ***************/ 
                   3086: 
                   3087: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   3088: {
1.138     brouard  3089:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  3090:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  3091:      model to the ncovmodel covariates (including constant and age).
                   3092:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3093:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3094:      ncth covariate in the global vector x is given by the formula:
                   3095:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3096:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3097:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3098:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  3099:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  3100:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  3101:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  3102:   */
                   3103:   double s1, lnpijopii;
1.126     brouard  3104:   /*double t34;*/
1.164     brouard  3105:   int i,j, nc, ii, jj;
1.126     brouard  3106: 
1.223     brouard  3107:   for(i=1; i<= nlstate; i++){
                   3108:     for(j=1; j<i;j++){
                   3109:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3110:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3111:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3112:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3113:       }
                   3114:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3115:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3116:     }
                   3117:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3118:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3119:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3120:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3121:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3122:       }
                   3123:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3124:     }
                   3125:   }
1.218     brouard  3126:   
1.223     brouard  3127:   for(i=1; i<= nlstate; i++){
                   3128:     s1=0;
                   3129:     for(j=1; j<i; j++){
                   3130:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3131:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3132:     }
                   3133:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3134:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3135:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3136:     }
                   3137:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3138:     ps[i][i]=1./(s1+1.);
                   3139:     /* Computing other pijs */
                   3140:     for(j=1; j<i; j++)
1.325   ! brouard  3141:       ps[i][j]= exp(ps[i][j])*ps[i][i];/* Bug valgrind */
1.223     brouard  3142:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3143:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3144:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3145:   } /* end i */
1.218     brouard  3146:   
1.223     brouard  3147:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3148:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3149:       ps[ii][jj]=0;
                   3150:       ps[ii][ii]=1;
                   3151:     }
                   3152:   }
1.294     brouard  3153: 
                   3154: 
1.223     brouard  3155:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3156:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3157:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3158:   /*   } */
                   3159:   /*   printf("\n "); */
                   3160:   /* } */
                   3161:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3162:   /*
                   3163:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  3164:                goto end;*/
1.266     brouard  3165:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  3166: }
                   3167: 
1.218     brouard  3168: /*************** backward transition probabilities ***************/ 
                   3169: 
                   3170:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3171: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3172:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   3173: {
1.302     brouard  3174:   /* Computes the backward probability at age agefin, cov[2], and covariate combination 'ij'. In fact cov is already filled and x too.
1.266     brouard  3175:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  3176:    */
1.218     brouard  3177:   int i, ii, j,k;
1.222     brouard  3178:   
                   3179:   double **out, **pmij();
                   3180:   double sumnew=0.;
1.218     brouard  3181:   double agefin;
1.292     brouard  3182:   double k3=0.; /* constant of the w_x diagonal matrix (in order for B to sum to 1 even for death state) */
1.222     brouard  3183:   double **dnewm, **dsavm, **doldm;
                   3184:   double **bbmij;
                   3185:   
1.218     brouard  3186:   doldm=ddoldms; /* global pointers */
1.222     brouard  3187:   dnewm=ddnewms;
                   3188:   dsavm=ddsavms;
1.318     brouard  3189: 
                   3190:   /* Debug */
                   3191:   /* printf("Bmij ij=%d, cov[2}=%f\n", ij, cov[2]); */
1.222     brouard  3192:   agefin=cov[2];
1.268     brouard  3193:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3194:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3195:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3196:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3197: 
                   3198:   /* P_x */
1.325   ! brouard  3199:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm *//* Bug valgrind */
1.268     brouard  3200:   /* outputs pmmij which is a stochastic matrix in row */
                   3201: 
                   3202:   /* Diag(w_x) */
1.292     brouard  3203:   /* Rescaling the cross-sectional prevalence: Problem with prevacurrent which can be zero */
1.268     brouard  3204:   sumnew=0.;
1.269     brouard  3205:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3206:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.297     brouard  3207:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]); */
1.268     brouard  3208:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3209:   }
                   3210:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3211:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3212:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3213:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3214:     }
                   3215:   }else{
                   3216:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3217:       for (j=1;j<=nlstate+ndeath;j++)
                   3218:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3219:     }
                   3220:     /* if(sumnew <0.9){ */
                   3221:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3222:     /* } */
                   3223:   }
                   3224:   k3=0.0;  /* We put the last diagonal to 0 */
                   3225:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3226:       doldm[ii][ii]= k3;
                   3227:   }
                   3228:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3229:   
1.292     brouard  3230:   /* Left product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm): diag[(w_i)*Px */
                   3231:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* was a Bug Valgrind */
1.268     brouard  3232: 
1.292     brouard  3233:   /* Diag(Sum_i w^i_x p^ij_x, should be the prevalence at age x+stepm */
1.268     brouard  3234:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3235:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3236:     sumnew=0.;
1.222     brouard  3237:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3238:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3239:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3240:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3241:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3242:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3243:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3244:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3245:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3246:        /* }else */
1.268     brouard  3247:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3248:     } /*End ii */
                   3249:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3250: 
1.292     brouard  3251:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* was a Bug Valgrind */
1.268     brouard  3252:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3253:   /* end bmij */
1.266     brouard  3254:   return ps; /*pointer is unchanged */
1.218     brouard  3255: }
1.217     brouard  3256: /*************** transition probabilities ***************/ 
                   3257: 
1.218     brouard  3258: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3259: {
                   3260:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3261:      computes the probability to be observed in state j being in state i by appying the
                   3262:      model to the ncovmodel covariates (including constant and age).
                   3263:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3264:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3265:      ncth covariate in the global vector x is given by the formula:
                   3266:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3267:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3268:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3269:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3270:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3271:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3272:   */
                   3273:   double s1, lnpijopii;
                   3274:   /*double t34;*/
                   3275:   int i,j, nc, ii, jj;
                   3276: 
1.234     brouard  3277:   for(i=1; i<= nlstate; i++){
                   3278:     for(j=1; j<i;j++){
                   3279:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3280:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3281:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3282:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3283:       }
                   3284:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3285:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3286:     }
                   3287:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3288:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3289:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3290:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3291:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3292:       }
                   3293:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3294:     }
                   3295:   }
                   3296:   
                   3297:   for(i=1; i<= nlstate; i++){
                   3298:     s1=0;
                   3299:     for(j=1; j<i; j++){
                   3300:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3301:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3302:     }
                   3303:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3304:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3305:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3306:     }
                   3307:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3308:     ps[i][i]=1./(s1+1.);
                   3309:     /* Computing other pijs */
                   3310:     for(j=1; j<i; j++)
                   3311:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3312:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3313:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3314:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3315:   } /* end i */
                   3316:   
                   3317:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3318:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3319:       ps[ii][jj]=0;
                   3320:       ps[ii][ii]=1;
                   3321:     }
                   3322:   }
1.296     brouard  3323:   /* Added for prevbcast */ /* Transposed matrix too */
1.234     brouard  3324:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3325:     s1=0.;
                   3326:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3327:       s1+=ps[ii][jj];
                   3328:     }
                   3329:     for(ii=1; ii<= nlstate; ii++){
                   3330:       ps[ii][jj]=ps[ii][jj]/s1;
                   3331:     }
                   3332:   }
                   3333:   /* Transposition */
                   3334:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3335:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3336:       s1=ps[ii][jj];
                   3337:       ps[ii][jj]=ps[jj][ii];
                   3338:       ps[jj][ii]=s1;
                   3339:     }
                   3340:   }
                   3341:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3342:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3343:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3344:   /*   } */
                   3345:   /*   printf("\n "); */
                   3346:   /* } */
                   3347:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3348:   /*
                   3349:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3350:     goto end;*/
                   3351:   return ps;
1.217     brouard  3352: }
                   3353: 
                   3354: 
1.126     brouard  3355: /**************** Product of 2 matrices ******************/
                   3356: 
1.145     brouard  3357: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3358: {
                   3359:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3360:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3361:   /* in, b, out are matrice of pointers which should have been initialized 
                   3362:      before: only the contents of out is modified. The function returns
                   3363:      a pointer to pointers identical to out */
1.145     brouard  3364:   int i, j, k;
1.126     brouard  3365:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3366:     for(k=ncolol; k<=ncoloh; k++){
                   3367:       out[i][k]=0.;
                   3368:       for(j=ncl; j<=nch; j++)
                   3369:        out[i][k] +=in[i][j]*b[j][k];
                   3370:     }
1.126     brouard  3371:   return out;
                   3372: }
                   3373: 
                   3374: 
                   3375: /************* Higher Matrix Product ***************/
                   3376: 
1.235     brouard  3377: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3378: {
1.218     brouard  3379:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3380:      'nhstepm*hstepm*stepm' months (i.e. until
                   3381:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3382:      nhstepm*hstepm matrices. 
                   3383:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3384:      (typically every 2 years instead of every month which is too big 
                   3385:      for the memory).
                   3386:      Model is determined by parameters x and covariates have to be 
                   3387:      included manually here. 
                   3388: 
                   3389:      */
                   3390: 
                   3391:   int i, j, d, h, k;
1.131     brouard  3392:   double **out, cov[NCOVMAX+1];
1.126     brouard  3393:   double **newm;
1.187     brouard  3394:   double agexact;
1.214     brouard  3395:   double agebegin, ageend;
1.126     brouard  3396: 
                   3397:   /* Hstepm could be zero and should return the unit matrix */
                   3398:   for (i=1;i<=nlstate+ndeath;i++)
                   3399:     for (j=1;j<=nlstate+ndeath;j++){
                   3400:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3401:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3402:     }
                   3403:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3404:   for(h=1; h <=nhstepm; h++){
                   3405:     for(d=1; d <=hstepm; d++){
                   3406:       newm=savm;
                   3407:       /* Covariates have to be included here again */
                   3408:       cov[1]=1.;
1.214     brouard  3409:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3410:       cov[2]=agexact;
1.319     brouard  3411:       if(nagesqr==1){
1.227     brouard  3412:        cov[3]= agexact*agexact;
1.319     brouard  3413:       }
1.235     brouard  3414:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
1.319     brouard  3415: /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3416:        /* codtabm(ij,k)  (1 & (ij-1) >> (k-1))+1 */
                   3417: /*             V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   3418: /*    k        1  2   3   4     5    6    7     8    9 */
                   3419: /*Tvar[k]=     5  4   3   6     5    2    7     1    1 */
                   3420: /*    nsd         1   2                              3 */ /* Counting single dummies covar fixed or tv */
                   3421: /*TvarsD[nsd]     4   3                              1 */ /* ID of single dummy cova fixed or timevary*/
                   3422: /*TvarsDind[k]    2   3                              9 */ /* position K of single dummy cova */
1.235     brouard  3423:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3424:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3425:       }
                   3426:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3427:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.319     brouard  3428:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k];
1.235     brouard  3429:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3430:       }
1.319     brouard  3431:       for (k=1; k<=cptcovage;k++){ /* For product with age V1+V1*age +V4 +age*V3 */
                   3432:        /* 1+2 Tage[1]=2 TVar[2]=1 Dummy[2]=2, Tage[2]=4 TVar[4]=3 Dummy[4]=3 quant*/
                   3433:        /* */
                   3434:        if(Dummy[Tage[k]]== 2){ /* dummy with age */
                   3435:        /* if(Dummy[Tvar[Tage[k]]]== 2){ /\* dummy with age *\/ */
1.235     brouard  3436:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319     brouard  3437:        } else if(Dummy[Tage[k]]== 3){ /* quantitative with age */
                   3438:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k];
1.235     brouard  3439:        }
                   3440:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3441:       }
1.319     brouard  3442:       for (k=1; k<=cptcovprod;k++){ /*  For product without age */
1.235     brouard  3443:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.319     brouard  3444:        /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   3445:        if(Dummy[Tvard[k][1]==0]){
                   3446:          if(Dummy[Tvard[k][2]==0]){
                   3447:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3448:          }else{
                   3449:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   3450:          }
                   3451:        }else{
                   3452:          if(Dummy[Tvard[k][2]==0]){
                   3453:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   3454:          }else{
                   3455:            cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   3456:          }
                   3457:        }
1.235     brouard  3458:       }
                   3459:       /* for (k=1; k<=cptcovn;k++)  */
                   3460:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3461:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3462:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3463:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3464:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3465:       
                   3466:       
1.126     brouard  3467:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3468:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.319     brouard  3469:       /* right multiplication of oldm by the current matrix */
1.126     brouard  3470:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3471:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3472:       /* if((int)age == 70){ */
                   3473:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3474:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3475:       /*         printf("%d pmmij ",i); */
                   3476:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3477:       /*           printf("%f ",pmmij[i][j]); */
                   3478:       /*         } */
                   3479:       /*         printf(" oldm "); */
                   3480:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3481:       /*           printf("%f ",oldm[i][j]); */
                   3482:       /*         } */
                   3483:       /*         printf("\n"); */
                   3484:       /*       } */
                   3485:       /* } */
1.126     brouard  3486:       savm=oldm;
                   3487:       oldm=newm;
                   3488:     }
                   3489:     for(i=1; i<=nlstate+ndeath; i++)
                   3490:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3491:        po[i][j][h]=newm[i][j];
                   3492:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3493:       }
1.128     brouard  3494:     /*printf("h=%d ",h);*/
1.126     brouard  3495:   } /* end h */
1.267     brouard  3496:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3497:   return po;
                   3498: }
                   3499: 
1.217     brouard  3500: /************* Higher Back Matrix Product ***************/
1.218     brouard  3501: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3502: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3503: {
1.266     brouard  3504:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3505:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3506:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3507:      nhstepm*hstepm matrices.
                   3508:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3509:      (typically every 2 years instead of every month which is too big
1.217     brouard  3510:      for the memory).
1.218     brouard  3511:      Model is determined by parameters x and covariates have to be
1.266     brouard  3512:      included manually here. Then we use a call to bmij(x and cov)
                   3513:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3514:   */
1.217     brouard  3515: 
                   3516:   int i, j, d, h, k;
1.266     brouard  3517:   double **out, cov[NCOVMAX+1], **bmij();
                   3518:   double **newm, ***newmm;
1.217     brouard  3519:   double agexact;
                   3520:   double agebegin, ageend;
1.222     brouard  3521:   double **oldm, **savm;
1.217     brouard  3522: 
1.266     brouard  3523:   newmm=po; /* To be saved */
                   3524:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3525:   /* Hstepm could be zero and should return the unit matrix */
                   3526:   for (i=1;i<=nlstate+ndeath;i++)
                   3527:     for (j=1;j<=nlstate+ndeath;j++){
                   3528:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3529:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3530:     }
                   3531:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3532:   for(h=1; h <=nhstepm; h++){
                   3533:     for(d=1; d <=hstepm; d++){
                   3534:       newm=savm;
                   3535:       /* Covariates have to be included here again */
                   3536:       cov[1]=1.;
1.271     brouard  3537:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3538:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
1.318     brouard  3539:         /* Debug */
                   3540:       /* printf("hBxij age=%lf, agexact=%lf\n", age, agexact); */
1.217     brouard  3541:       cov[2]=agexact;
                   3542:       if(nagesqr==1)
1.222     brouard  3543:        cov[3]= agexact*agexact;
1.325   ! brouard  3544:       for (k=1; k<=nsd;k++){ /* For single dummy covariates only *//* cptcovn error */
1.266     brouard  3545:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3546:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
1.325   ! brouard  3547:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];/* Bug valgrind */
1.266     brouard  3548:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3549:       }
1.267     brouard  3550:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3551:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3552:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3553:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3554:       }
1.319     brouard  3555:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 *//* For product with age */
                   3556:        /* if(Dummy[Tvar[Tage[k]]]== 2){ /\* dummy with age error!!!*\/ */
                   3557:        if(Dummy[Tage[k]]== 2){ /* dummy with age */
1.267     brouard  3558:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.319     brouard  3559:        } else if(Dummy[Tage[k]]== 3){ /* quantitative with age */
1.267     brouard  3560:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3561:        }
                   3562:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3563:       }
                   3564:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3565:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.325   ! brouard  3566:        if(Dummy[Tvard[k][1]==0]){
        !          3567:          if(Dummy[Tvard[k][2]==0]){
        !          3568:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
        !          3569:          }else{
        !          3570:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
        !          3571:          }
        !          3572:        }else{
        !          3573:          if(Dummy[Tvard[k][2]==0]){
        !          3574:            cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
        !          3575:          }else{
        !          3576:            cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
        !          3577:          }
        !          3578:        }
1.267     brouard  3579:       }                        
1.217     brouard  3580:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3581:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3582: 
1.218     brouard  3583:       /* Careful transposed matrix */
1.266     brouard  3584:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3585:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3586:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3587:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.325   ! brouard  3588:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);/* Bug valgrind */
1.217     brouard  3589:       /* if((int)age == 70){ */
                   3590:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3591:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3592:       /*         printf("%d pmmij ",i); */
                   3593:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3594:       /*           printf("%f ",pmmij[i][j]); */
                   3595:       /*         } */
                   3596:       /*         printf(" oldm "); */
                   3597:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3598:       /*           printf("%f ",oldm[i][j]); */
                   3599:       /*         } */
                   3600:       /*         printf("\n"); */
                   3601:       /*       } */
                   3602:       /* } */
                   3603:       savm=oldm;
                   3604:       oldm=newm;
                   3605:     }
                   3606:     for(i=1; i<=nlstate+ndeath; i++)
                   3607:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3608:        po[i][j][h]=newm[i][j];
1.268     brouard  3609:        /* if(h==nhstepm) */
                   3610:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3611:       }
1.268     brouard  3612:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3613:   } /* end h */
1.268     brouard  3614:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3615:   return po;
                   3616: }
                   3617: 
                   3618: 
1.162     brouard  3619: #ifdef NLOPT
                   3620:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3621:   double fret;
                   3622:   double *xt;
                   3623:   int j;
                   3624:   myfunc_data *d2 = (myfunc_data *) pd;
                   3625: /* xt = (p1-1); */
                   3626:   xt=vector(1,n); 
                   3627:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3628: 
                   3629:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3630:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3631:   printf("Function = %.12lf ",fret);
                   3632:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3633:   printf("\n");
                   3634:  free_vector(xt,1,n);
                   3635:   return fret;
                   3636: }
                   3637: #endif
1.126     brouard  3638: 
                   3639: /*************** log-likelihood *************/
                   3640: double func( double *x)
                   3641: {
1.226     brouard  3642:   int i, ii, j, k, mi, d, kk;
                   3643:   int ioffset=0;
                   3644:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3645:   double **out;
                   3646:   double lli; /* Individual log likelihood */
                   3647:   int s1, s2;
1.228     brouard  3648:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3649:   double bbh, survp;
                   3650:   long ipmx;
                   3651:   double agexact;
                   3652:   /*extern weight */
                   3653:   /* We are differentiating ll according to initial status */
                   3654:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3655:   /*for(i=1;i<imx;i++) 
                   3656:     printf(" %d\n",s[4][i]);
                   3657:   */
1.162     brouard  3658: 
1.226     brouard  3659:   ++countcallfunc;
1.162     brouard  3660: 
1.226     brouard  3661:   cov[1]=1.;
1.126     brouard  3662: 
1.226     brouard  3663:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3664:   ioffset=0;
1.226     brouard  3665:   if(mle==1){
                   3666:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3667:       /* Computes the values of the ncovmodel covariates of the model
                   3668:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3669:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3670:         to be observed in j being in i according to the model.
                   3671:       */
1.243     brouard  3672:       ioffset=2+nagesqr ;
1.233     brouard  3673:    /* Fixed */
1.319     brouard  3674:       for (k=1; k<=ncovf;k++){ /* For each fixed covariate dummu or quant or prod */
                   3675:        /* # V1=sex, V2=raedyrs Quant Fixed, State=livarnb4..livarnb11, V3=iadl4..iald11, V4=adlw4..adlw11, V5=r4bmi..r11bmi */
                   3676:         /*             V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   3677:        /*  TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  ID of fixed covariates or product V2, V1*V2, V1 */
1.320     brouard  3678:         /* TvarFind;  TvarFind[1]=6,  TvarFind[2]=7, TvarFind[3]=9 *//* Inverse V2(6) is first fixed (single or prod)  */
1.319     brouard  3679:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (TvarFind[1]=6)*/
                   3680:        /* V1*V2 (7)  TvarFind[2]=7, TvarFind[3]=9 */
1.234     brouard  3681:       }
1.226     brouard  3682:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
1.319     brouard  3683:         is 5, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2]=6 
1.226     brouard  3684:         has been calculated etc */
                   3685:       /* For an individual i, wav[i] gives the number of effective waves */
                   3686:       /* We compute the contribution to Likelihood of each effective transition
                   3687:         mw[mi][i] is real wave of the mi th effectve wave */
                   3688:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3689:         s2=s[mw[mi+1][i]][i];
                   3690:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3691:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3692:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3693:       */
                   3694:       for(mi=1; mi<= wav[i]-1; mi++){
1.319     brouard  3695:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates in the model (single and product but no age )"V5+V4+V3+V4*V3+V5*age+V1*age+V1" +TvarVind 1,2,3,4(V4*V3)  Tvar[1]@7{5, 4, 3, 6, 5, 1, 1 ; 6 because the created covar is after V5 and is 6, minus 1+1, 3,2,1,4 positions in cotvar*/
                   3696:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; but where is the crossproduct? */
1.242     brouard  3697:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3698:        }
                   3699:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3700:          for (j=1;j<=nlstate+ndeath;j++){
                   3701:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3702:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3703:          }
                   3704:        for(d=0; d<dh[mi][i]; d++){
                   3705:          newm=savm;
                   3706:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3707:          cov[2]=agexact;
                   3708:          if(nagesqr==1)
                   3709:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3710:          for (kk=1; kk<=cptcovage;kk++) {
1.318     brouard  3711:            if(!FixedV[Tvar[Tage[kk]]])
                   3712:              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
                   3713:            else
                   3714:              cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3715:          }
                   3716:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3717:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3718:          savm=oldm;
                   3719:          oldm=newm;
                   3720:        } /* end mult */
                   3721:        
                   3722:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3723:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3724:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3725:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3726:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3727:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3728:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3729:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3730:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3731:                                 * -stepm/2 to stepm/2 .
                   3732:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3733:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3734:                                 */
1.234     brouard  3735:        s1=s[mw[mi][i]][i];
                   3736:        s2=s[mw[mi+1][i]][i];
                   3737:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3738:        /* bias bh is positive if real duration
                   3739:         * is higher than the multiple of stepm and negative otherwise.
                   3740:         */
                   3741:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3742:        if( s2 > nlstate){ 
                   3743:          /* i.e. if s2 is a death state and if the date of death is known 
                   3744:             then the contribution to the likelihood is the probability to 
                   3745:             die between last step unit time and current  step unit time, 
                   3746:             which is also equal to probability to die before dh 
                   3747:             minus probability to die before dh-stepm . 
                   3748:             In version up to 0.92 likelihood was computed
                   3749:             as if date of death was unknown. Death was treated as any other
                   3750:             health state: the date of the interview describes the actual state
                   3751:             and not the date of a change in health state. The former idea was
                   3752:             to consider that at each interview the state was recorded
                   3753:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3754:             introduced the exact date of death then we should have modified
                   3755:             the contribution of an exact death to the likelihood. This new
                   3756:             contribution is smaller and very dependent of the step unit
                   3757:             stepm. It is no more the probability to die between last interview
                   3758:             and month of death but the probability to survive from last
                   3759:             interview up to one month before death multiplied by the
                   3760:             probability to die within a month. Thanks to Chris
                   3761:             Jackson for correcting this bug.  Former versions increased
                   3762:             mortality artificially. The bad side is that we add another loop
                   3763:             which slows down the processing. The difference can be up to 10%
                   3764:             lower mortality.
                   3765:          */
                   3766:          /* If, at the beginning of the maximization mostly, the
                   3767:             cumulative probability or probability to be dead is
                   3768:             constant (ie = 1) over time d, the difference is equal to
                   3769:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3770:             s1 at precedent wave, to be dead a month before current
                   3771:             wave is equal to probability, being at state s1 at
                   3772:             precedent wave, to be dead at mont of the current
                   3773:             wave. Then the observed probability (that this person died)
                   3774:             is null according to current estimated parameter. In fact,
                   3775:             it should be very low but not zero otherwise the log go to
                   3776:             infinity.
                   3777:          */
1.183     brouard  3778: /* #ifdef INFINITYORIGINAL */
                   3779: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3780: /* #else */
                   3781: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3782: /*         lli=log(mytinydouble); */
                   3783: /*       else */
                   3784: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3785: /* #endif */
1.226     brouard  3786:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3787:          
1.226     brouard  3788:        } else if  ( s2==-1 ) { /* alive */
                   3789:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3790:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3791:          /*survp += out[s1][j]; */
                   3792:          lli= log(survp);
                   3793:        }
                   3794:        else if  (s2==-4) { 
                   3795:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3796:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3797:          lli= log(survp); 
                   3798:        } 
                   3799:        else if  (s2==-5) { 
                   3800:          for (j=1,survp=0. ; j<=2; j++)  
                   3801:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3802:          lli= log(survp); 
                   3803:        } 
                   3804:        else{
                   3805:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3806:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3807:        } 
                   3808:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3809:        /*if(lli ==000.0)*/
                   3810:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3811:        ipmx +=1;
                   3812:        sw += weight[i];
                   3813:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3814:        /* if (lli < log(mytinydouble)){ */
                   3815:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3816:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3817:        /* } */
                   3818:       } /* end of wave */
                   3819:     } /* end of individual */
                   3820:   }  else if(mle==2){
                   3821:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.319     brouard  3822:       ioffset=2+nagesqr ;
                   3823:       for (k=1; k<=ncovf;k++)
                   3824:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];
1.226     brouard  3825:       for(mi=1; mi<= wav[i]-1; mi++){
1.319     brouard  3826:        for(k=1; k <= ncovv ; k++){
                   3827:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3828:        }
1.226     brouard  3829:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3830:          for (j=1;j<=nlstate+ndeath;j++){
                   3831:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3832:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3833:          }
                   3834:        for(d=0; d<=dh[mi][i]; d++){
                   3835:          newm=savm;
                   3836:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3837:          cov[2]=agexact;
                   3838:          if(nagesqr==1)
                   3839:            cov[3]= agexact*agexact;
                   3840:          for (kk=1; kk<=cptcovage;kk++) {
                   3841:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3842:          }
                   3843:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3844:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3845:          savm=oldm;
                   3846:          oldm=newm;
                   3847:        } /* end mult */
                   3848:       
                   3849:        s1=s[mw[mi][i]][i];
                   3850:        s2=s[mw[mi+1][i]][i];
                   3851:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3852:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3853:        ipmx +=1;
                   3854:        sw += weight[i];
                   3855:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3856:       } /* end of wave */
                   3857:     } /* end of individual */
                   3858:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3859:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3860:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3861:       for(mi=1; mi<= wav[i]-1; mi++){
                   3862:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3863:          for (j=1;j<=nlstate+ndeath;j++){
                   3864:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3865:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3866:          }
                   3867:        for(d=0; d<dh[mi][i]; d++){
                   3868:          newm=savm;
                   3869:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3870:          cov[2]=agexact;
                   3871:          if(nagesqr==1)
                   3872:            cov[3]= agexact*agexact;
                   3873:          for (kk=1; kk<=cptcovage;kk++) {
                   3874:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3875:          }
                   3876:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3877:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3878:          savm=oldm;
                   3879:          oldm=newm;
                   3880:        } /* end mult */
                   3881:       
                   3882:        s1=s[mw[mi][i]][i];
                   3883:        s2=s[mw[mi+1][i]][i];
                   3884:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3885:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3886:        ipmx +=1;
                   3887:        sw += weight[i];
                   3888:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3889:       } /* end of wave */
                   3890:     } /* end of individual */
                   3891:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3892:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3893:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3894:       for(mi=1; mi<= wav[i]-1; mi++){
                   3895:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3896:          for (j=1;j<=nlstate+ndeath;j++){
                   3897:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3898:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3899:          }
                   3900:        for(d=0; d<dh[mi][i]; d++){
                   3901:          newm=savm;
                   3902:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3903:          cov[2]=agexact;
                   3904:          if(nagesqr==1)
                   3905:            cov[3]= agexact*agexact;
                   3906:          for (kk=1; kk<=cptcovage;kk++) {
                   3907:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3908:          }
1.126     brouard  3909:        
1.226     brouard  3910:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3911:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3912:          savm=oldm;
                   3913:          oldm=newm;
                   3914:        } /* end mult */
                   3915:       
                   3916:        s1=s[mw[mi][i]][i];
                   3917:        s2=s[mw[mi+1][i]][i];
                   3918:        if( s2 > nlstate){ 
                   3919:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3920:        } else if  ( s2==-1 ) { /* alive */
                   3921:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3922:            survp += out[s1][j];
                   3923:          lli= log(survp);
                   3924:        }else{
                   3925:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3926:        }
                   3927:        ipmx +=1;
                   3928:        sw += weight[i];
                   3929:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3930: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3931:       } /* end of wave */
                   3932:     } /* end of individual */
                   3933:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3934:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3935:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3936:       for(mi=1; mi<= wav[i]-1; mi++){
                   3937:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3938:          for (j=1;j<=nlstate+ndeath;j++){
                   3939:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3940:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3941:          }
                   3942:        for(d=0; d<dh[mi][i]; d++){
                   3943:          newm=savm;
                   3944:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3945:          cov[2]=agexact;
                   3946:          if(nagesqr==1)
                   3947:            cov[3]= agexact*agexact;
                   3948:          for (kk=1; kk<=cptcovage;kk++) {
                   3949:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3950:          }
1.126     brouard  3951:        
1.226     brouard  3952:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3953:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3954:          savm=oldm;
                   3955:          oldm=newm;
                   3956:        } /* end mult */
                   3957:       
                   3958:        s1=s[mw[mi][i]][i];
                   3959:        s2=s[mw[mi+1][i]][i];
                   3960:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3961:        ipmx +=1;
                   3962:        sw += weight[i];
                   3963:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3964:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3965:       } /* end of wave */
                   3966:     } /* end of individual */
                   3967:   } /* End of if */
                   3968:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3969:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3970:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3971:   return -l;
1.126     brouard  3972: }
                   3973: 
                   3974: /*************** log-likelihood *************/
                   3975: double funcone( double *x)
                   3976: {
1.228     brouard  3977:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3978:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3979:   int ioffset=0;
1.131     brouard  3980:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3981:   double **out;
                   3982:   double lli; /* Individual log likelihood */
                   3983:   double llt;
                   3984:   int s1, s2;
1.228     brouard  3985:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3986: 
1.126     brouard  3987:   double bbh, survp;
1.187     brouard  3988:   double agexact;
1.214     brouard  3989:   double agebegin, ageend;
1.126     brouard  3990:   /*extern weight */
                   3991:   /* We are differentiating ll according to initial status */
                   3992:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3993:   /*for(i=1;i<imx;i++) 
                   3994:     printf(" %d\n",s[4][i]);
                   3995:   */
                   3996:   cov[1]=1.;
                   3997: 
                   3998:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3999:   ioffset=0;
                   4000:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  4001:     /* ioffset=2+nagesqr+cptcovage; */
                   4002:     ioffset=2+nagesqr;
1.232     brouard  4003:     /* Fixed */
1.224     brouard  4004:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  4005:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
1.311     brouard  4006:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products *//* Missing values are set to -1 but should be dropped */
1.232     brouard  4007:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   4008: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   4009: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   4010: /*    cov[2+6]=covar[2][i]; V2  */
                   4011: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   4012: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   4013: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   4014: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   4015: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   4016: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  4017:     }
1.232     brouard  4018:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   4019:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   4020:     /* } */
1.231     brouard  4021:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   4022:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   4023:     /* } */
1.225     brouard  4024:     
1.233     brouard  4025: 
                   4026:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  4027:     /* Wave varying (but not age varying) */
                   4028:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  4029:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   4030:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   4031:       }
1.232     brouard  4032:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  4033:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   4034:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   4035:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   4036:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   4037:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  4038:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  4039:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   4040:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   4041:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  4042:       /* } */
1.126     brouard  4043:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  4044:        for (j=1;j<=nlstate+ndeath;j++){
                   4045:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   4046:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   4047:        }
1.214     brouard  4048:       
                   4049:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   4050:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   4051:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  4052:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  4053:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4054:          and mw[mi+1][i]. dh depends on stepm.*/
                   4055:        newm=savm;
1.247     brouard  4056:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  4057:        cov[2]=agexact;
                   4058:        if(nagesqr==1)
                   4059:          cov[3]= agexact*agexact;
                   4060:        for (kk=1; kk<=cptcovage;kk++) {
                   4061:          if(!FixedV[Tvar[Tage[kk]]])
                   4062:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   4063:          else
                   4064:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   4065:        }
                   4066:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   4067:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   4068:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   4069:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   4070:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   4071:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   4072:        savm=oldm;
                   4073:        oldm=newm;
1.126     brouard  4074:       } /* end mult */
                   4075:       
                   4076:       s1=s[mw[mi][i]][i];
                   4077:       s2=s[mw[mi+1][i]][i];
1.217     brouard  4078:       /* if(s2==-1){ */
1.268     brouard  4079:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  4080:       /*       /\* exit(1); *\/ */
                   4081:       /* } */
1.126     brouard  4082:       bbh=(double)bh[mi][i]/(double)stepm; 
                   4083:       /* bias is positive if real duration
                   4084:        * is higher than the multiple of stepm and negative otherwise.
                   4085:        */
                   4086:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  4087:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  4088:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  4089:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   4090:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   4091:        lli= log(survp);
1.126     brouard  4092:       }else if (mle==1){
1.242     brouard  4093:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  4094:       } else if(mle==2){
1.242     brouard  4095:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  4096:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  4097:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  4098:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  4099:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  4100:       } else{  /* mle=0 back to 1 */
1.242     brouard  4101:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   4102:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  4103:       } /* End of if */
                   4104:       ipmx +=1;
                   4105:       sw += weight[i];
                   4106:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  4107:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  4108:       if(globpr){
1.246     brouard  4109:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  4110:  %11.6f %11.6f %11.6f ", \
1.242     brouard  4111:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  4112:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  4113:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   4114:          llt +=ll[k]*gipmx/gsw;
                   4115:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   4116:        }
                   4117:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  4118:       }
1.232     brouard  4119:        } /* end of wave */
                   4120: } /* end of individual */
                   4121: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   4122: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   4123: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   4124: if(globpr==0){ /* First time we count the contributions and weights */
                   4125:        gipmx=ipmx;
                   4126:        gsw=sw;
                   4127: }
                   4128: return -l;
1.126     brouard  4129: }
                   4130: 
                   4131: 
                   4132: /*************** function likelione ***********/
1.292     brouard  4133: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*func)(double []))
1.126     brouard  4134: {
                   4135:   /* This routine should help understanding what is done with 
                   4136:      the selection of individuals/waves and
                   4137:      to check the exact contribution to the likelihood.
                   4138:      Plotting could be done.
                   4139:    */
                   4140:   int k;
                   4141: 
                   4142:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  4143:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  4144:     strcat(fileresilk,fileresu);
1.126     brouard  4145:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   4146:       printf("Problem with resultfile: %s\n", fileresilk);
                   4147:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   4148:     }
1.214     brouard  4149:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   4150:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  4151:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   4152:     for(k=1; k<=nlstate; k++) 
                   4153:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   4154:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   4155:   }
                   4156: 
1.292     brouard  4157:   *fretone=(*func)(p);
1.126     brouard  4158:   if(*globpri !=0){
                   4159:     fclose(ficresilk);
1.205     brouard  4160:     if (mle ==0)
                   4161:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   4162:     else if(mle >=1)
                   4163:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   4164:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  4165:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  4166:       
                   4167:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  4168:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  4169: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   4170:     }
1.207     brouard  4171:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  4172: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4173:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  4174: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4175:     fflush(fichtm);
1.205     brouard  4176:   }
1.126     brouard  4177:   return;
                   4178: }
                   4179: 
                   4180: 
                   4181: /*********** Maximum Likelihood Estimation ***************/
                   4182: 
                   4183: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   4184: {
1.319     brouard  4185:   int i,j,k, jk, jkk=0, iter=0;
1.126     brouard  4186:   double **xi;
                   4187:   double fret;
                   4188:   double fretone; /* Only one call to likelihood */
                   4189:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  4190: 
                   4191: #ifdef NLOPT
                   4192:   int creturn;
                   4193:   nlopt_opt opt;
                   4194:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   4195:   double *lb;
                   4196:   double minf; /* the minimum objective value, upon return */
                   4197:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   4198:   myfunc_data dinst, *d = &dinst;
                   4199: #endif
                   4200: 
                   4201: 
1.126     brouard  4202:   xi=matrix(1,npar,1,npar);
                   4203:   for (i=1;i<=npar;i++)
                   4204:     for (j=1;j<=npar;j++)
                   4205:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   4206:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  4207:   strcpy(filerespow,"POW_"); 
1.126     brouard  4208:   strcat(filerespow,fileres);
                   4209:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   4210:     printf("Problem with resultfile: %s\n", filerespow);
                   4211:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   4212:   }
                   4213:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   4214:   for (i=1;i<=nlstate;i++)
                   4215:     for(j=1;j<=nlstate+ndeath;j++)
                   4216:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   4217:   fprintf(ficrespow,"\n");
1.162     brouard  4218: #ifdef POWELL
1.319     brouard  4219: #ifdef LINMINORIGINAL
                   4220: #else /* LINMINORIGINAL */
                   4221:   
                   4222:   flatdir=ivector(1,npar); 
                   4223:   for (j=1;j<=npar;j++) flatdir[j]=0; 
                   4224: #endif /*LINMINORIGINAL */
                   4225: 
                   4226: #ifdef FLATSUP
                   4227:   powell(p,xi,npar,ftol,&iter,&fret,flatdir,func);
                   4228:   /* reorganizing p by suppressing flat directions */
                   4229:   for(i=1, jk=1; i <=nlstate; i++){
                   4230:     for(k=1; k <=(nlstate+ndeath); k++){
                   4231:       if (k != i) {
                   4232:         printf("%d%d flatdir[%d]=%d",i,k,jk, flatdir[jk]);
                   4233:         if(flatdir[jk]==1){
                   4234:           printf(" To be skipped %d%d flatdir[%d]=%d ",i,k,jk, flatdir[jk]);
                   4235:         }
                   4236:         for(j=1; j <=ncovmodel; j++){
                   4237:           printf("%12.7f ",p[jk]);
                   4238:           jk++; 
                   4239:         }
                   4240:         printf("\n");
                   4241:       }
                   4242:     }
                   4243:   }
                   4244: /* skipping */
                   4245:   /* for(i=1, jk=1, jkk=1;(flatdir[jk]==0)&& (i <=nlstate); i++){ */
                   4246:   for(i=1, jk=1, jkk=1;i <=nlstate; i++){
                   4247:     for(k=1; k <=(nlstate+ndeath); k++){
                   4248:       if (k != i) {
                   4249:         printf("%d%d flatdir[%d]=%d",i,k,jk, flatdir[jk]);
                   4250:         if(flatdir[jk]==1){
                   4251:           printf(" To be skipped %d%d flatdir[%d]=%d jk=%d p[%d] ",i,k,jk, flatdir[jk],jk, jk);
                   4252:           for(j=1; j <=ncovmodel;  jk++,j++){
                   4253:             printf(" p[%d]=%12.7f",jk, p[jk]);
                   4254:             /*q[jjk]=p[jk];*/
                   4255:           }
                   4256:         }else{
                   4257:           printf(" To be kept %d%d flatdir[%d]=%d jk=%d q[%d]=p[%d] ",i,k,jk, flatdir[jk],jk, jkk, jk);
                   4258:           for(j=1; j <=ncovmodel;  jk++,jkk++,j++){
                   4259:             printf(" p[%d]=%12.7f=q[%d]",jk, p[jk],jkk);
                   4260:             /*q[jjk]=p[jk];*/
                   4261:           }
                   4262:         }
                   4263:         printf("\n");
                   4264:       }
                   4265:       fflush(stdout);
                   4266:     }
                   4267:   }
                   4268:   powell(p,xi,npar,ftol,&iter,&fret,flatdir,func);
                   4269: #else  /* FLATSUP */
1.126     brouard  4270:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.319     brouard  4271: #endif  /* FLATSUP */
                   4272: 
                   4273: #ifdef LINMINORIGINAL
                   4274: #else
                   4275:       free_ivector(flatdir,1,npar); 
                   4276: #endif  /* LINMINORIGINAL*/
                   4277: #endif /* POWELL */
1.126     brouard  4278: 
1.162     brouard  4279: #ifdef NLOPT
                   4280: #ifdef NEWUOA
                   4281:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   4282: #else
                   4283:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   4284: #endif
                   4285:   lb=vector(0,npar-1);
                   4286:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   4287:   nlopt_set_lower_bounds(opt, lb);
                   4288:   nlopt_set_initial_step1(opt, 0.1);
                   4289:   
                   4290:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   4291:   d->function = func;
                   4292:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   4293:   nlopt_set_min_objective(opt, myfunc, d);
                   4294:   nlopt_set_xtol_rel(opt, ftol);
                   4295:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   4296:     printf("nlopt failed! %d\n",creturn); 
                   4297:   }
                   4298:   else {
                   4299:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4300:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4301:     iter=1; /* not equal */
                   4302:   }
                   4303:   nlopt_destroy(opt);
                   4304: #endif
1.319     brouard  4305: #ifdef FLATSUP
                   4306:   /* npared = npar -flatd/ncovmodel; */
                   4307:   /* xired= matrix(1,npared,1,npared); */
                   4308:   /* paramred= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */
                   4309:   /* powell(pred,xired,npared,ftol,&iter,&fret,flatdir,func); */
                   4310:   /* free_matrix(xire,1,npared,1,npared); */
                   4311: #else  /* FLATSUP */
                   4312: #endif /* FLATSUP */
1.126     brouard  4313:   free_matrix(xi,1,npar,1,npar);
                   4314:   fclose(ficrespow);
1.203     brouard  4315:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4316:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4317:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4318: 
                   4319: }
                   4320: 
                   4321: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4322: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4323: {
                   4324:   double  **a,**y,*x,pd;
1.203     brouard  4325:   /* double **hess; */
1.164     brouard  4326:   int i, j;
1.126     brouard  4327:   int *indx;
                   4328: 
                   4329:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4330:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4331:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4332:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4333:   double gompertz(double p[]);
1.203     brouard  4334:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4335: 
                   4336:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4337:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4338:   for (i=1;i<=npar;i++){
1.203     brouard  4339:     printf("%d-",i);fflush(stdout);
                   4340:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4341:    
                   4342:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4343:     
                   4344:     /*  printf(" %f ",p[i]);
                   4345:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4346:   }
                   4347:   
                   4348:   for (i=1;i<=npar;i++) {
                   4349:     for (j=1;j<=npar;j++)  {
                   4350:       if (j>i) { 
1.203     brouard  4351:        printf(".%d-%d",i,j);fflush(stdout);
                   4352:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4353:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4354:        
                   4355:        hess[j][i]=hess[i][j];    
                   4356:        /*printf(" %lf ",hess[i][j]);*/
                   4357:       }
                   4358:     }
                   4359:   }
                   4360:   printf("\n");
                   4361:   fprintf(ficlog,"\n");
                   4362: 
                   4363:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4364:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4365:   
                   4366:   a=matrix(1,npar,1,npar);
                   4367:   y=matrix(1,npar,1,npar);
                   4368:   x=vector(1,npar);
                   4369:   indx=ivector(1,npar);
                   4370:   for (i=1;i<=npar;i++)
                   4371:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4372:   ludcmp(a,npar,indx,&pd);
                   4373: 
                   4374:   for (j=1;j<=npar;j++) {
                   4375:     for (i=1;i<=npar;i++) x[i]=0;
                   4376:     x[j]=1;
                   4377:     lubksb(a,npar,indx,x);
                   4378:     for (i=1;i<=npar;i++){ 
                   4379:       matcov[i][j]=x[i];
                   4380:     }
                   4381:   }
                   4382: 
                   4383:   printf("\n#Hessian matrix#\n");
                   4384:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4385:   for (i=1;i<=npar;i++) { 
                   4386:     for (j=1;j<=npar;j++) { 
1.203     brouard  4387:       printf("%.6e ",hess[i][j]);
                   4388:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4389:     }
                   4390:     printf("\n");
                   4391:     fprintf(ficlog,"\n");
                   4392:   }
                   4393: 
1.203     brouard  4394:   /* printf("\n#Covariance matrix#\n"); */
                   4395:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4396:   /* for (i=1;i<=npar;i++) {  */
                   4397:   /*   for (j=1;j<=npar;j++) {  */
                   4398:   /*     printf("%.6e ",matcov[i][j]); */
                   4399:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4400:   /*   } */
                   4401:   /*   printf("\n"); */
                   4402:   /*   fprintf(ficlog,"\n"); */
                   4403:   /* } */
                   4404: 
1.126     brouard  4405:   /* Recompute Inverse */
1.203     brouard  4406:   /* for (i=1;i<=npar;i++) */
                   4407:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4408:   /* ludcmp(a,npar,indx,&pd); */
                   4409: 
                   4410:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4411: 
                   4412:   /* for (j=1;j<=npar;j++) { */
                   4413:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4414:   /*   x[j]=1; */
                   4415:   /*   lubksb(a,npar,indx,x); */
                   4416:   /*   for (i=1;i<=npar;i++){  */
                   4417:   /*     y[i][j]=x[i]; */
                   4418:   /*     printf("%.3e ",y[i][j]); */
                   4419:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4420:   /*   } */
                   4421:   /*   printf("\n"); */
                   4422:   /*   fprintf(ficlog,"\n"); */
                   4423:   /* } */
                   4424: 
                   4425:   /* Verifying the inverse matrix */
                   4426: #ifdef DEBUGHESS
                   4427:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4428: 
1.203     brouard  4429:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4430:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4431: 
                   4432:   for (j=1;j<=npar;j++) {
                   4433:     for (i=1;i<=npar;i++){ 
1.203     brouard  4434:       printf("%.2f ",y[i][j]);
                   4435:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4436:     }
                   4437:     printf("\n");
                   4438:     fprintf(ficlog,"\n");
                   4439:   }
1.203     brouard  4440: #endif
1.126     brouard  4441: 
                   4442:   free_matrix(a,1,npar,1,npar);
                   4443:   free_matrix(y,1,npar,1,npar);
                   4444:   free_vector(x,1,npar);
                   4445:   free_ivector(indx,1,npar);
1.203     brouard  4446:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4447: 
                   4448: 
                   4449: }
                   4450: 
                   4451: /*************** hessian matrix ****************/
                   4452: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4453: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4454:   int i;
                   4455:   int l=1, lmax=20;
1.203     brouard  4456:   double k1,k2, res, fx;
1.132     brouard  4457:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4458:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4459:   int k=0,kmax=10;
                   4460:   double l1;
                   4461: 
                   4462:   fx=func(x);
                   4463:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4464:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4465:     l1=pow(10,l);
                   4466:     delts=delt;
                   4467:     for(k=1 ; k <kmax; k=k+1){
                   4468:       delt = delta*(l1*k);
                   4469:       p2[theta]=x[theta] +delt;
1.145     brouard  4470:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4471:       p2[theta]=x[theta]-delt;
                   4472:       k2=func(p2)-fx;
                   4473:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4474:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4475:       
1.203     brouard  4476: #ifdef DEBUGHESSII
1.126     brouard  4477:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4478:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4479: #endif
                   4480:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4481:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4482:        k=kmax;
                   4483:       }
                   4484:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4485:        k=kmax; l=lmax*10;
1.126     brouard  4486:       }
                   4487:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4488:        delts=delt;
                   4489:       }
1.203     brouard  4490:     } /* End loop k */
1.126     brouard  4491:   }
                   4492:   delti[theta]=delts;
                   4493:   return res; 
                   4494:   
                   4495: }
                   4496: 
1.203     brouard  4497: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4498: {
                   4499:   int i;
1.164     brouard  4500:   int l=1, lmax=20;
1.126     brouard  4501:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4502:   double p2[MAXPARM+1];
1.203     brouard  4503:   int k, kmax=1;
                   4504:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4505: 
                   4506:   int firstime=0;
1.203     brouard  4507:   
1.126     brouard  4508:   fx=func(x);
1.203     brouard  4509:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4510:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4511:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4512:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4513:     k1=func(p2)-fx;
                   4514:   
1.203     brouard  4515:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4516:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4517:     k2=func(p2)-fx;
                   4518:   
1.203     brouard  4519:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4520:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4521:     k3=func(p2)-fx;
                   4522:   
1.203     brouard  4523:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4524:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4525:     k4=func(p2)-fx;
1.203     brouard  4526:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4527:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4528:       firstime=1;
1.203     brouard  4529:       kmax=kmax+10;
1.208     brouard  4530:     }
                   4531:     if(kmax >=10 || firstime ==1){
1.246     brouard  4532:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4533:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4534:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4535:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4536:     }
                   4537: #ifdef DEBUGHESSIJ
                   4538:     v1=hess[thetai][thetai];
                   4539:     v2=hess[thetaj][thetaj];
                   4540:     cv12=res;
                   4541:     /* Computing eigen value of Hessian matrix */
                   4542:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4543:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4544:     if ((lc2 <0) || (lc1 <0) ){
                   4545:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4546:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4547:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4548:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4549:     }
1.126     brouard  4550: #endif
                   4551:   }
                   4552:   return res;
                   4553: }
                   4554: 
1.203     brouard  4555:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4556: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4557: /* { */
                   4558: /*   int i; */
                   4559: /*   int l=1, lmax=20; */
                   4560: /*   double k1,k2,k3,k4,res,fx; */
                   4561: /*   double p2[MAXPARM+1]; */
                   4562: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4563: /*   int k=0,kmax=10; */
                   4564: /*   double l1; */
                   4565:   
                   4566: /*   fx=func(x); */
                   4567: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4568: /*     l1=pow(10,l); */
                   4569: /*     delts=delt; */
                   4570: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4571: /*       delt = delti*(l1*k); */
                   4572: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4573: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4574: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4575: /*       k1=func(p2)-fx; */
                   4576:       
                   4577: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4578: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4579: /*       k2=func(p2)-fx; */
                   4580:       
                   4581: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4582: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4583: /*       k3=func(p2)-fx; */
                   4584:       
                   4585: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4586: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4587: /*       k4=func(p2)-fx; */
                   4588: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4589: /* #ifdef DEBUGHESSIJ */
                   4590: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4591: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4592: /* #endif */
                   4593: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4594: /*     k=kmax; */
                   4595: /*       } */
                   4596: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4597: /*     k=kmax; l=lmax*10; */
                   4598: /*       } */
                   4599: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4600: /*     delts=delt; */
                   4601: /*       } */
                   4602: /*     } /\* End loop k *\/ */
                   4603: /*   } */
                   4604: /*   delti[theta]=delts; */
                   4605: /*   return res;  */
                   4606: /* } */
                   4607: 
                   4608: 
1.126     brouard  4609: /************** Inverse of matrix **************/
                   4610: void ludcmp(double **a, int n, int *indx, double *d) 
                   4611: { 
                   4612:   int i,imax,j,k; 
                   4613:   double big,dum,sum,temp; 
                   4614:   double *vv; 
                   4615:  
                   4616:   vv=vector(1,n); 
                   4617:   *d=1.0; 
                   4618:   for (i=1;i<=n;i++) { 
                   4619:     big=0.0; 
                   4620:     for (j=1;j<=n;j++) 
                   4621:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4622:     if (big == 0.0){
                   4623:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4624:       for (j=1;j<=n;j++) {
                   4625:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4626:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4627:       }
                   4628:       fflush(ficlog);
                   4629:       fclose(ficlog);
                   4630:       nrerror("Singular matrix in routine ludcmp"); 
                   4631:     }
1.126     brouard  4632:     vv[i]=1.0/big; 
                   4633:   } 
                   4634:   for (j=1;j<=n;j++) { 
                   4635:     for (i=1;i<j;i++) { 
                   4636:       sum=a[i][j]; 
                   4637:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4638:       a[i][j]=sum; 
                   4639:     } 
                   4640:     big=0.0; 
                   4641:     for (i=j;i<=n;i++) { 
                   4642:       sum=a[i][j]; 
                   4643:       for (k=1;k<j;k++) 
                   4644:        sum -= a[i][k]*a[k][j]; 
                   4645:       a[i][j]=sum; 
                   4646:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4647:        big=dum; 
                   4648:        imax=i; 
                   4649:       } 
                   4650:     } 
                   4651:     if (j != imax) { 
                   4652:       for (k=1;k<=n;k++) { 
                   4653:        dum=a[imax][k]; 
                   4654:        a[imax][k]=a[j][k]; 
                   4655:        a[j][k]=dum; 
                   4656:       } 
                   4657:       *d = -(*d); 
                   4658:       vv[imax]=vv[j]; 
                   4659:     } 
                   4660:     indx[j]=imax; 
                   4661:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4662:     if (j != n) { 
                   4663:       dum=1.0/(a[j][j]); 
                   4664:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4665:     } 
                   4666:   } 
                   4667:   free_vector(vv,1,n);  /* Doesn't work */
                   4668: ;
                   4669: } 
                   4670: 
                   4671: void lubksb(double **a, int n, int *indx, double b[]) 
                   4672: { 
                   4673:   int i,ii=0,ip,j; 
                   4674:   double sum; 
                   4675:  
                   4676:   for (i=1;i<=n;i++) { 
                   4677:     ip=indx[i]; 
                   4678:     sum=b[ip]; 
                   4679:     b[ip]=b[i]; 
                   4680:     if (ii) 
                   4681:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4682:     else if (sum) ii=i; 
                   4683:     b[i]=sum; 
                   4684:   } 
                   4685:   for (i=n;i>=1;i--) { 
                   4686:     sum=b[i]; 
                   4687:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4688:     b[i]=sum/a[i][i]; 
                   4689:   } 
                   4690: } 
                   4691: 
                   4692: void pstamp(FILE *fichier)
                   4693: {
1.196     brouard  4694:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4695: }
                   4696: 
1.297     brouard  4697: void date2dmy(double date,double *day, double *month, double *year){
                   4698:   double yp=0., yp1=0., yp2=0.;
                   4699:   
                   4700:   yp1=modf(date,&yp);/* extracts integral of date in yp  and
                   4701:                        fractional in yp1 */
                   4702:   *year=yp;
                   4703:   yp2=modf((yp1*12),&yp);
                   4704:   *month=yp;
                   4705:   yp1=modf((yp2*30.5),&yp);
                   4706:   *day=yp;
                   4707:   if(*day==0) *day=1;
                   4708:   if(*month==0) *month=1;
                   4709: }
                   4710: 
1.253     brouard  4711: 
                   4712: 
1.126     brouard  4713: /************ Frequencies ********************/
1.251     brouard  4714: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4715:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4716:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4717: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4718:   
1.265     brouard  4719:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4720:   int iind=0, iage=0;
                   4721:   int mi; /* Effective wave */
                   4722:   int first;
                   4723:   double ***freq; /* Frequencies */
1.268     brouard  4724:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4725:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4726:   double *meanq, *stdq, *idq;
1.226     brouard  4727:   double **meanqt;
                   4728:   double *pp, **prop, *posprop, *pospropt;
                   4729:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4730:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4731:   double agebegin, ageend;
                   4732:     
                   4733:   pp=vector(1,nlstate);
1.251     brouard  4734:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4735:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4736:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4737:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4738:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4739:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4740:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4741:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4742:   strcpy(fileresp,"P_");
                   4743:   strcat(fileresp,fileresu);
                   4744:   /*strcat(fileresphtm,fileresu);*/
                   4745:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4746:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4747:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4748:     exit(0);
                   4749:   }
1.240     brouard  4750:   
1.226     brouard  4751:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4752:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4753:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4754:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4755:     fflush(ficlog);
                   4756:     exit(70); 
                   4757:   }
                   4758:   else{
                   4759:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4760: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4761: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4762:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4763:   }
1.319     brouard  4764:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies (weight=%d) and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm, weightopt);
1.240     brouard  4765:   
1.226     brouard  4766:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4767:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4768:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4769:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4770:     fflush(ficlog);
                   4771:     exit(70); 
1.240     brouard  4772:   } else{
1.226     brouard  4773:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.319     brouard  4774: ,<hr size=\"2\" color=\"#EC5E5E\"> \n                                  \
1.214     brouard  4775: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4776:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4777:   }
1.319     brouard  4778:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>(weight=%d) frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr,weightopt);
1.240     brouard  4779:   
1.253     brouard  4780:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4781:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4782:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4783:   j1=0;
1.126     brouard  4784:   
1.227     brouard  4785:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4786:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4787:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4788:   
                   4789:   
1.226     brouard  4790:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4791:      reference=low_education V1=0,V2=0
                   4792:      med_educ                V1=1 V2=0, 
                   4793:      high_educ               V1=0 V2=1
                   4794:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4795:   */
1.249     brouard  4796:   dateintsum=0;
                   4797:   k2cpt=0;
                   4798: 
1.253     brouard  4799:   if(cptcoveff == 0 )
1.265     brouard  4800:     nl=1;  /* Constant and age model only */
1.253     brouard  4801:   else
                   4802:     nl=2;
1.265     brouard  4803: 
                   4804:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4805:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4806:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4807:    *     freq[s1][s2][iage] =0.
                   4808:    *     Loop on iind
                   4809:    *       ++freq[s1][s2][iage] weighted
                   4810:    *     end iind
                   4811:    *     if covariate and j!0
                   4812:    *       headers Variable on one line
                   4813:    *     endif cov j!=0
                   4814:    *     header of frequency table by age
                   4815:    *     Loop on age
                   4816:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4817:    *       pos+=freq[s1][s2][iage] weighted
                   4818:    *       Loop on s1 initial state
                   4819:    *         fprintf(ficresp
                   4820:    *       end s1
                   4821:    *     end age
                   4822:    *     if j!=0 computes starting values
                   4823:    *     end compute starting values
                   4824:    *   end j1
                   4825:    * end nl 
                   4826:    */
1.253     brouard  4827:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4828:     if(nj==1)
                   4829:       j=0;  /* First pass for the constant */
1.265     brouard  4830:     else{
1.253     brouard  4831:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4832:     }
1.251     brouard  4833:     first=1;
1.265     brouard  4834:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4835:       posproptt=0.;
                   4836:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4837:        scanf("%d", i);*/
                   4838:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4839:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4840:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4841:            freq[i][s2][m]=0;
1.251     brouard  4842:       
                   4843:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4844:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4845:          prop[i][m]=0;
                   4846:        posprop[i]=0;
                   4847:        pospropt[i]=0;
                   4848:       }
1.283     brouard  4849:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4850:         idq[z1]=0.;
                   4851:         meanq[z1]=0.;
                   4852:         stdq[z1]=0.;
1.283     brouard  4853:       }
                   4854:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4855:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4856:       /*         meanqt[m][z1]=0.; */
                   4857:       /*       } */
                   4858:       /* }       */
1.251     brouard  4859:       /* dateintsum=0; */
                   4860:       /* k2cpt=0; */
                   4861:       
1.265     brouard  4862:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4863:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4864:        bool=1;
                   4865:        if(j !=0){
                   4866:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4867:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4868:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4869:                /* if(Tvaraff[z1] ==-20){ */
                   4870:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4871:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4872:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4873:                /* }else  */
                   4874:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4875:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4876:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4877:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4878:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4879:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4880:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4881:                } /* Onlyf fixed */
                   4882:              } /* end z1 */
                   4883:            } /* cptcovn > 0 */
                   4884:          } /* end any */
                   4885:        }/* end j==0 */
1.265     brouard  4886:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4887:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4888:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4889:            m=mw[mi][iind];
                   4890:            if(j!=0){
                   4891:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4892:                for (z1=1; z1<=cptcoveff; z1++) {
                   4893:                  if( Fixed[Tmodelind[z1]]==1){
                   4894:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4895:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4896:                                                                                      value is -1, we don't select. It differs from the 
                   4897:                                                                                      constant and age model which counts them. */
                   4898:                      bool=0; /* not selected */
                   4899:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4900:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4901:                      bool=0;
                   4902:                    }
                   4903:                  }
                   4904:                }
                   4905:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4906:            } /* end j==0 */
                   4907:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4908:            if(bool==1){ /*Selected */
1.251     brouard  4909:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4910:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4911:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4912:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4913:              if(m >=firstpass && m <=lastpass){
                   4914:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4915:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4916:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4917:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4918:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4919:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4920:                if (m<lastpass) {
                   4921:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4922:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4923:                  if(s[m][iind]==-1)
                   4924:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4925:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.311     brouard  4926:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean on known values only */
                   4927:                    if(!isnan(covar[ncovcol+z1][iind])){
                   4928:                        idq[z1]=idq[z1]+weight[iind];
                   4929:                        meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4930:                        /* stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; *//*error*/
                   4931:                        stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4932:                    }
1.284     brouard  4933:                  }
1.251     brouard  4934:                  /* if((int)agev[m][iind] == 55) */
                   4935:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4936:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4937:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4938:                }
1.251     brouard  4939:              } /* end if between passes */  
                   4940:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4941:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4942:                k2cpt++;
                   4943:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4944:              }
1.251     brouard  4945:            }else{
                   4946:              bool=1;
                   4947:            }/* end bool 2 */
                   4948:          } /* end m */
1.284     brouard  4949:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4950:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4951:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4952:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4953:          /* } */
1.251     brouard  4954:        } /* end bool */
                   4955:       } /* end iind = 1 to imx */
1.319     brouard  4956:       /* prop[s][age] is fed for any initial and valid live state as well as
1.251     brouard  4957:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4958:       
                   4959:       
                   4960:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4961:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4962:         pstamp(ficresp);
1.251     brouard  4963:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4964:         pstamp(ficresp);
1.251     brouard  4965:        printf( "\n#********** Variable "); 
                   4966:        fprintf(ficresp, "\n#********** Variable "); 
                   4967:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4968:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4969:        fprintf(ficlog, "\n#********** Variable "); 
                   4970:        for (z1=1; z1<=cptcoveff; z1++){
                   4971:          if(!FixedV[Tvaraff[z1]]){
                   4972:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4973:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4974:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4975:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4976:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4977:          }else{
1.251     brouard  4978:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4979:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4980:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4981:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4982:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4983:          }
                   4984:        }
                   4985:        printf( "**********\n#");
                   4986:        fprintf(ficresp, "**********\n#");
                   4987:        fprintf(ficresphtm, "**********</h3>\n");
                   4988:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4989:        fprintf(ficlog, "**********\n");
                   4990:       }
1.284     brouard  4991:       /*
                   4992:        Printing means of quantitative variables if any
                   4993:       */
                   4994:       for (z1=1; z1<= nqfveff; z1++) {
1.311     brouard  4995:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.3g (weighted) individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.312     brouard  4996:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
1.284     brouard  4997:        if(weightopt==1){
                   4998:          printf(" Weighted mean and standard deviation of");
                   4999:          fprintf(ficlog," Weighted mean and standard deviation of");
                   5000:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   5001:        }
1.311     brouard  5002:        /* mu = \frac{w x}{\sum w}
                   5003:            var = \frac{\sum w (x-mu)^2}{\sum w} = \frac{w x^2}{\sum w} - mu^2 
                   5004:        */
                   5005:        printf(" fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   5006:        fprintf(ficlog," fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   5007:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.3g (weighted) representatives of the population : %8.5g (%8.5g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
1.284     brouard  5008:       }
                   5009:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   5010:       /*       for(m=1;m<=lastpass;m++){ */
                   5011:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   5012:       /*   } */
                   5013:       /* } */
1.283     brouard  5014: 
1.251     brouard  5015:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  5016:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   5017:         fprintf(ficresp, " Age");
                   5018:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  5019:       for(i=1; i<=nlstate;i++) {
1.265     brouard  5020:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  5021:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   5022:       }
1.265     brouard  5023:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  5024:       fprintf(ficresphtm, "\n");
                   5025:       
                   5026:       /* Header of frequency table by age */
                   5027:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   5028:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  5029:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  5030:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  5031:          if(s2!=0 && m!=0)
                   5032:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  5033:        }
1.226     brouard  5034:       }
1.251     brouard  5035:       fprintf(ficresphtmfr, "\n");
                   5036:     
                   5037:       /* For each age */
                   5038:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   5039:        fprintf(ficresphtm,"<tr>");
                   5040:        if(iage==iagemax+1){
                   5041:          fprintf(ficlog,"1");
                   5042:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   5043:        }else if(iage==iagemax+2){
                   5044:          fprintf(ficlog,"0");
                   5045:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   5046:        }else if(iage==iagemax+3){
                   5047:          fprintf(ficlog,"Total");
                   5048:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   5049:        }else{
1.240     brouard  5050:          if(first==1){
1.251     brouard  5051:            first=0;
                   5052:            printf("See log file for details...\n");
                   5053:          }
                   5054:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   5055:          fprintf(ficlog,"Age %d", iage);
                   5056:        }
1.265     brouard  5057:        for(s1=1; s1 <=nlstate ; s1++){
                   5058:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   5059:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  5060:        }
1.265     brouard  5061:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  5062:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  5063:            pos += freq[s1][m][iage];
                   5064:          if(pp[s1]>=1.e-10){
1.251     brouard  5065:            if(first==1){
1.265     brouard  5066:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  5067:            }
1.265     brouard  5068:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  5069:          }else{
                   5070:            if(first==1)
1.265     brouard  5071:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   5072:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  5073:          }
                   5074:        }
                   5075:       
1.265     brouard  5076:        for(s1=1; s1 <=nlstate ; s1++){ 
                   5077:          /* posprop[s1]=0; */
                   5078:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   5079:            pp[s1] += freq[s1][m][iage];
                   5080:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   5081:       
                   5082:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   5083:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   5084:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   5085:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   5086:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   5087:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   5088:        }
                   5089:        
                   5090:        /* Writing ficresp */
                   5091:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   5092:           if( iage <= iagemax){
                   5093:            fprintf(ficresp," %d",iage);
                   5094:           }
                   5095:         }else if( nj==2){
                   5096:           if( iage <= iagemax){
                   5097:            fprintf(ficresp," %d",iage);
                   5098:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   5099:           }
1.240     brouard  5100:        }
1.265     brouard  5101:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  5102:          if(pos>=1.e-5){
1.251     brouard  5103:            if(first==1)
1.265     brouard  5104:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   5105:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  5106:          }else{
                   5107:            if(first==1)
1.265     brouard  5108:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   5109:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  5110:          }
                   5111:          if( iage <= iagemax){
                   5112:            if(pos>=1.e-5){
1.265     brouard  5113:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   5114:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   5115:               }else if( nj==2){
                   5116:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   5117:               }
                   5118:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   5119:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   5120:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   5121:            } else{
                   5122:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   5123:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  5124:            }
1.240     brouard  5125:          }
1.265     brouard  5126:          pospropt[s1] +=posprop[s1];
                   5127:        } /* end loop s1 */
1.251     brouard  5128:        /* pospropt=0.; */
1.265     brouard  5129:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  5130:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  5131:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  5132:              if(first==1){
1.265     brouard  5133:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  5134:              }
1.265     brouard  5135:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   5136:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  5137:            }
1.265     brouard  5138:            if(s1!=0 && m!=0)
                   5139:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  5140:          }
1.265     brouard  5141:        } /* end loop s1 */
1.251     brouard  5142:        posproptt=0.; 
1.265     brouard  5143:        for(s1=1; s1 <=nlstate; s1++){
                   5144:          posproptt += pospropt[s1];
1.251     brouard  5145:        }
                   5146:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  5147:        fprintf(ficresphtm,"</tr>\n");
                   5148:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   5149:          if(iage <= iagemax)
                   5150:            fprintf(ficresp,"\n");
1.240     brouard  5151:        }
1.251     brouard  5152:        if(first==1)
                   5153:          printf("Others in log...\n");
                   5154:        fprintf(ficlog,"\n");
                   5155:       } /* end loop age iage */
1.265     brouard  5156:       
1.251     brouard  5157:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  5158:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  5159:        if(posproptt < 1.e-5){
1.265     brouard  5160:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  5161:        }else{
1.265     brouard  5162:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  5163:        }
1.226     brouard  5164:       }
1.251     brouard  5165:       fprintf(ficresphtm,"</tr>\n");
                   5166:       fprintf(ficresphtm,"</table>\n");
                   5167:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  5168:       if(posproptt < 1.e-5){
1.251     brouard  5169:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   5170:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  5171:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   5172:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  5173:        invalidvarcomb[j1]=1;
1.226     brouard  5174:       }else{
1.251     brouard  5175:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   5176:        invalidvarcomb[j1]=0;
1.226     brouard  5177:       }
1.251     brouard  5178:       fprintf(ficresphtmfr,"</table>\n");
                   5179:       fprintf(ficlog,"\n");
                   5180:       if(j!=0){
                   5181:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  5182:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  5183:          for(k=1; k <=(nlstate+ndeath); k++){
                   5184:            if (k != i) {
1.265     brouard  5185:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  5186:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  5187:                  if(j1==1){ /* All dummy covariates to zero */
                   5188:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   5189:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  5190:                    printf("%d%d ",i,k);
                   5191:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  5192:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   5193:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   5194:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  5195:                  }
1.253     brouard  5196:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   5197:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   5198:                    x[iage]= (double)iage;
                   5199:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  5200:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  5201:                  }
1.268     brouard  5202:                  /* Some are not finite, but linreg will ignore these ages */
                   5203:                  no=0;
1.253     brouard  5204:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  5205:                  pstart[s1]=b;
                   5206:                  pstart[s1-1]=a;
1.252     brouard  5207:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   5208:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   5209:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  5210:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  5211:                  printf("%d%d ",i,k);
                   5212:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  5213:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  5214:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   5215:                  ;
                   5216:                }
                   5217:                /* printf("%12.7f )", param[i][jj][k]); */
                   5218:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5219:                s1++; 
1.251     brouard  5220:              } /* end jj */
                   5221:            } /* end k!= i */
                   5222:          } /* end k */
1.265     brouard  5223:        } /* end i, s1 */
1.251     brouard  5224:       } /* end j !=0 */
                   5225:     } /* end selected combination of covariate j1 */
                   5226:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   5227:       printf("#Freqsummary: Starting values for the constants:\n");
                   5228:       fprintf(ficlog,"\n");
1.265     brouard  5229:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  5230:        for(k=1; k <=(nlstate+ndeath); k++){
                   5231:          if (k != i) {
                   5232:            printf("%d%d ",i,k);
                   5233:            fprintf(ficlog,"%d%d ",i,k);
                   5234:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  5235:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  5236:              if(jj==1){ /* Age has to be done */
1.265     brouard  5237:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   5238:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   5239:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  5240:              }
                   5241:              /* printf("%12.7f )", param[i][jj][k]); */
                   5242:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5243:              s1++; 
1.250     brouard  5244:            }
1.251     brouard  5245:            printf("\n");
                   5246:            fprintf(ficlog,"\n");
1.250     brouard  5247:          }
                   5248:        }
1.284     brouard  5249:       } /* end of state i */
1.251     brouard  5250:       printf("#Freqsummary\n");
                   5251:       fprintf(ficlog,"\n");
1.265     brouard  5252:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   5253:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   5254:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   5255:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5256:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5257:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   5258:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   5259:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  5260:          /* } */
                   5261:        }
1.265     brouard  5262:       } /* end loop s1 */
1.251     brouard  5263:       
                   5264:       printf("\n");
                   5265:       fprintf(ficlog,"\n");
                   5266:     } /* end j=0 */
1.249     brouard  5267:   } /* end j */
1.252     brouard  5268: 
1.253     brouard  5269:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  5270:     for(i=1, jk=1; i <=nlstate; i++){
                   5271:       for(j=1; j <=nlstate+ndeath; j++){
                   5272:        if(j!=i){
                   5273:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   5274:          printf("%1d%1d",i,j);
                   5275:          fprintf(ficparo,"%1d%1d",i,j);
                   5276:          for(k=1; k<=ncovmodel;k++){
                   5277:            /*    printf(" %lf",param[i][j][k]); */
                   5278:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   5279:            p[jk]=pstart[jk];
                   5280:            printf(" %f ",pstart[jk]);
                   5281:            fprintf(ficparo," %f ",pstart[jk]);
                   5282:            jk++;
                   5283:          }
                   5284:          printf("\n");
                   5285:          fprintf(ficparo,"\n");
                   5286:        }
                   5287:       }
                   5288:     }
                   5289:   } /* end mle=-2 */
1.226     brouard  5290:   dateintmean=dateintsum/k2cpt; 
1.296     brouard  5291:   date2dmy(dateintmean,&jintmean,&mintmean,&aintmean);
1.240     brouard  5292:   
1.226     brouard  5293:   fclose(ficresp);
                   5294:   fclose(ficresphtm);
                   5295:   fclose(ficresphtmfr);
1.283     brouard  5296:   free_vector(idq,1,nqfveff);
1.226     brouard  5297:   free_vector(meanq,1,nqfveff);
1.284     brouard  5298:   free_vector(stdq,1,nqfveff);
1.226     brouard  5299:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  5300:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   5301:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  5302:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5303:   free_vector(pospropt,1,nlstate);
                   5304:   free_vector(posprop,1,nlstate);
1.251     brouard  5305:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5306:   free_vector(pp,1,nlstate);
                   5307:   /* End of freqsummary */
                   5308: }
1.126     brouard  5309: 
1.268     brouard  5310: /* Simple linear regression */
                   5311: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   5312: 
                   5313:   /* y=a+bx regression */
                   5314:   double   sumx = 0.0;                        /* sum of x                      */
                   5315:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   5316:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   5317:   double   sumy = 0.0;                        /* sum of y                      */
                   5318:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   5319:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   5320:   double yhat;
                   5321:   
                   5322:   double denom=0;
                   5323:   int i;
                   5324:   int ne=*no;
                   5325:   
                   5326:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5327:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5328:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5329:       continue;
                   5330:     }
                   5331:     ne=ne+1;
                   5332:     sumx  += x[i];       
                   5333:     sumx2 += x[i]*x[i];  
                   5334:     sumxy += x[i] * y[i];
                   5335:     sumy  += y[i];      
                   5336:     sumy2 += y[i]*y[i]; 
                   5337:     denom = (ne * sumx2 - sumx*sumx);
                   5338:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5339:   } 
                   5340:   
                   5341:   denom = (ne * sumx2 - sumx*sumx);
                   5342:   if (denom == 0) {
                   5343:     // vertical, slope m is infinity
                   5344:     *b = INFINITY;
                   5345:     *a = 0;
                   5346:     if (r) *r = 0;
                   5347:     return 1;
                   5348:   }
                   5349:   
                   5350:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5351:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5352:   if (r!=NULL) {
                   5353:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5354:       sqrt((sumx2 - sumx*sumx/ne) *
                   5355:           (sumy2 - sumy*sumy/ne));
                   5356:   }
                   5357:   *no=ne;
                   5358:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5359:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5360:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5361:       continue;
                   5362:     }
                   5363:     ne=ne+1;
                   5364:     yhat = y[i] - *a -*b* x[i];
                   5365:     sume2  += yhat * yhat ;       
                   5366:     
                   5367:     denom = (ne * sumx2 - sumx*sumx);
                   5368:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5369:   } 
                   5370:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5371:   *sa= *sb * sqrt(sumx2/ne);
                   5372:   
                   5373:   return 0; 
                   5374: }
                   5375: 
1.126     brouard  5376: /************ Prevalence ********************/
1.227     brouard  5377: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5378: {  
                   5379:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5380:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5381:      We still use firstpass and lastpass as another selection.
                   5382:   */
1.126     brouard  5383:  
1.227     brouard  5384:   int i, m, jk, j1, bool, z1,j, iv;
                   5385:   int mi; /* Effective wave */
                   5386:   int iage;
                   5387:   double agebegin, ageend;
                   5388: 
                   5389:   double **prop;
                   5390:   double posprop; 
                   5391:   double  y2; /* in fractional years */
                   5392:   int iagemin, iagemax;
                   5393:   int first; /** to stop verbosity which is redirected to log file */
                   5394: 
                   5395:   iagemin= (int) agemin;
                   5396:   iagemax= (int) agemax;
                   5397:   /*pp=vector(1,nlstate);*/
1.251     brouard  5398:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5399:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5400:   j1=0;
1.222     brouard  5401:   
1.227     brouard  5402:   /*j=cptcoveff;*/
                   5403:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5404:   
1.288     brouard  5405:   first=0;
1.227     brouard  5406:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5407:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5408:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5409:        prop[i][iage]=0.0;
                   5410:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5411:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5412:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5413:     
                   5414:     for (i=1; i<=imx; i++) { /* Each individual */
                   5415:       bool=1;
                   5416:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5417:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5418:        m=mw[mi][i];
                   5419:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5420:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5421:        for (z1=1; z1<=cptcoveff; z1++){
                   5422:          if( Fixed[Tmodelind[z1]]==1){
                   5423:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5424:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5425:              bool=0;
                   5426:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5427:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5428:              bool=0;
                   5429:            }
                   5430:        }
                   5431:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5432:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5433:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5434:          if(m >=firstpass && m <=lastpass){
                   5435:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5436:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5437:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5438:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5439:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5440:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5441:                exit(1);
                   5442:              }
                   5443:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5444:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5445:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5446:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5447:              } /* end valid statuses */ 
                   5448:            } /* end selection of dates */
                   5449:          } /* end selection of waves */
                   5450:        } /* end bool */
                   5451:       } /* end wave */
                   5452:     } /* end individual */
                   5453:     for(i=iagemin; i <= iagemax+3; i++){  
                   5454:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5455:        posprop += prop[jk][i]; 
                   5456:       } 
                   5457:       
                   5458:       for(jk=1; jk <=nlstate ; jk++){      
                   5459:        if( i <=  iagemax){ 
                   5460:          if(posprop>=1.e-5){ 
                   5461:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5462:          } else{
1.288     brouard  5463:            if(!first){
                   5464:              first=1;
1.266     brouard  5465:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5466:            }else{
1.288     brouard  5467:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5468:            }
                   5469:          }
                   5470:        } 
                   5471:       }/* end jk */ 
                   5472:     }/* end i */ 
1.222     brouard  5473:      /*} *//* end i1 */
1.227     brouard  5474:   } /* end j1 */
1.222     brouard  5475:   
1.227     brouard  5476:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5477:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5478:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5479: }  /* End of prevalence */
1.126     brouard  5480: 
                   5481: /************* Waves Concatenation ***************/
                   5482: 
                   5483: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5484: {
1.298     brouard  5485:   /* Concatenates waves: wav[i] is the number of effective (useful waves in the sense that a non interview is useless) of individual i.
1.126     brouard  5486:      Death is a valid wave (if date is known).
                   5487:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5488:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
1.298     brouard  5489:      and mw[mi+1][i]. dh depends on stepm. s[m][i] exists for any wave from firstpass to lastpass
1.227     brouard  5490:   */
1.126     brouard  5491: 
1.224     brouard  5492:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5493:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5494:      double sum=0., jmean=0.;*/
1.224     brouard  5495:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5496:   int j, k=0,jk, ju, jl;
                   5497:   double sum=0.;
                   5498:   first=0;
1.214     brouard  5499:   firstwo=0;
1.217     brouard  5500:   firsthree=0;
1.218     brouard  5501:   firstfour=0;
1.164     brouard  5502:   jmin=100000;
1.126     brouard  5503:   jmax=-1;
                   5504:   jmean=0.;
1.224     brouard  5505: 
                   5506: /* Treating live states */
1.214     brouard  5507:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5508:     mi=0;  /* First valid wave */
1.227     brouard  5509:     mli=0; /* Last valid wave */
1.309     brouard  5510:     m=firstpass;  /* Loop on waves */
                   5511:     while(s[m][i] <= nlstate){  /* a live state or unknown state  */
1.227     brouard  5512:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5513:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5514:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
1.309     brouard  5515:        mw[++mi][i]=m; /* Valid wave: incrementing mi and updating mi; mw[mi] is the wave number of mi_th valid transition   */
1.227     brouard  5516:        mli=m;
1.224     brouard  5517:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5518:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5519:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5520:       }
1.309     brouard  5521:       else{ /* m = lastpass, eventual special issue with warning */
1.224     brouard  5522: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5523:        break;
1.224     brouard  5524: #else
1.317     brouard  5525:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){ /* no death date and known date of interview, case -2 (vital status unknown is warned later */
1.227     brouard  5526:          if(firsthree == 0){
1.302     brouard  5527:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5528:            firsthree=1;
1.317     brouard  5529:          }else if(firsthree >=1 && firsthree < 10){
                   5530:            fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
                   5531:            firsthree++;
                   5532:          }else if(firsthree == 10){
                   5533:            printf("Information, too many Information flags: no more reported to log either\n");
                   5534:            fprintf(ficlog,"Information, too many Information flags: no more reported to log either\n");
                   5535:            firsthree++;
                   5536:          }else{
                   5537:            firsthree++;
1.227     brouard  5538:          }
1.309     brouard  5539:          mw[++mi][i]=m; /* Valid transition with unknown status */
1.227     brouard  5540:          mli=m;
                   5541:        }
                   5542:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5543:          nbwarn++;
1.309     brouard  5544:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified?not a transition */
1.227     brouard  5545:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5546:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5547:          }
                   5548:          break;
                   5549:        }
                   5550:        break;
1.224     brouard  5551: #endif
1.227     brouard  5552:       }/* End m >= lastpass */
1.126     brouard  5553:     }/* end while */
1.224     brouard  5554: 
1.227     brouard  5555:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5556:     /* After last pass */
1.224     brouard  5557: /* Treating death states */
1.214     brouard  5558:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5559:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5560:       /* } */
1.126     brouard  5561:       mi++;    /* Death is another wave */
                   5562:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5563:       /* Only death is a correct wave */
1.126     brouard  5564:       mw[mi][i]=m;
1.257     brouard  5565:     } /* else not in a death state */
1.224     brouard  5566: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5567:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5568:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.309     brouard  5569:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* month of death occured before last wave month and status should have been death instead of -1 */
1.227     brouard  5570:          nbwarn++;
                   5571:          if(firstfiv==0){
1.309     brouard  5572:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5573:            firstfiv=1;
                   5574:          }else{
1.309     brouard  5575:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5576:          }
1.309     brouard  5577:            s[m][i]=nlstate+1; /* Fixing the status as death. Be careful if multiple death states */
                   5578:        }else{ /* Month of Death occured afer last wave month, potential bias */
1.227     brouard  5579:          nberr++;
                   5580:          if(firstwo==0){
1.309     brouard  5581:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5582:            firstwo=1;
                   5583:          }
1.309     brouard  5584:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5585:        }
1.257     brouard  5586:       }else{ /* if date of interview is unknown */
1.227     brouard  5587:        /* death is known but not confirmed by death status at any wave */
                   5588:        if(firstfour==0){
1.309     brouard  5589:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5590:          firstfour=1;
                   5591:        }
1.309     brouard  5592:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d  with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.214     brouard  5593:       }
1.224     brouard  5594:     } /* end if date of death is known */
                   5595: #endif
1.309     brouard  5596:     wav[i]=mi; /* mi should be the last effective wave (or mli),  */
                   5597:     /* wav[i]=mw[mi][i];   */
1.126     brouard  5598:     if(mi==0){
                   5599:       nbwarn++;
                   5600:       if(first==0){
1.227     brouard  5601:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5602:        first=1;
1.126     brouard  5603:       }
                   5604:       if(first==1){
1.227     brouard  5605:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5606:       }
                   5607:     } /* end mi==0 */
                   5608:   } /* End individuals */
1.214     brouard  5609:   /* wav and mw are no more changed */
1.223     brouard  5610:        
1.317     brouard  5611:   printf("Information, you have to check %d informations which haven't been logged!\n",firsthree);
                   5612:   fprintf(ficlog,"Information, you have to check %d informations which haven't been logged!\n",firsthree);
                   5613: 
                   5614: 
1.126     brouard  5615:   for(i=1; i<=imx; i++){
                   5616:     for(mi=1; mi<wav[i];mi++){
                   5617:       if (stepm <=0)
1.227     brouard  5618:        dh[mi][i]=1;
1.126     brouard  5619:       else{
1.260     brouard  5620:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5621:          if (agedc[i] < 2*AGESUP) {
                   5622:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5623:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5624:            else if(j<0){
                   5625:              nberr++;
                   5626:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5627:              j=1; /* Temporary Dangerous patch */
                   5628:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5629:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5630:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5631:            }
                   5632:            k=k+1;
                   5633:            if (j >= jmax){
                   5634:              jmax=j;
                   5635:              ijmax=i;
                   5636:            }
                   5637:            if (j <= jmin){
                   5638:              jmin=j;
                   5639:              ijmin=i;
                   5640:            }
                   5641:            sum=sum+j;
                   5642:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5643:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5644:          }
                   5645:        }
                   5646:        else{
                   5647:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5648: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5649:                                        
1.227     brouard  5650:          k=k+1;
                   5651:          if (j >= jmax) {
                   5652:            jmax=j;
                   5653:            ijmax=i;
                   5654:          }
                   5655:          else if (j <= jmin){
                   5656:            jmin=j;
                   5657:            ijmin=i;
                   5658:          }
                   5659:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5660:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5661:          if(j<0){
                   5662:            nberr++;
                   5663:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5664:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5665:          }
                   5666:          sum=sum+j;
                   5667:        }
                   5668:        jk= j/stepm;
                   5669:        jl= j -jk*stepm;
                   5670:        ju= j -(jk+1)*stepm;
                   5671:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5672:          if(jl==0){
                   5673:            dh[mi][i]=jk;
                   5674:            bh[mi][i]=0;
                   5675:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5676:                  * to avoid the price of an extra matrix product in likelihood */
                   5677:            dh[mi][i]=jk+1;
                   5678:            bh[mi][i]=ju;
                   5679:          }
                   5680:        }else{
                   5681:          if(jl <= -ju){
                   5682:            dh[mi][i]=jk;
                   5683:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5684:                                 * is higher than the multiple of stepm and negative otherwise.
                   5685:                                 */
                   5686:          }
                   5687:          else{
                   5688:            dh[mi][i]=jk+1;
                   5689:            bh[mi][i]=ju;
                   5690:          }
                   5691:          if(dh[mi][i]==0){
                   5692:            dh[mi][i]=1; /* At least one step */
                   5693:            bh[mi][i]=ju; /* At least one step */
                   5694:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5695:          }
                   5696:        } /* end if mle */
1.126     brouard  5697:       }
                   5698:     } /* end wave */
                   5699:   }
                   5700:   jmean=sum/k;
                   5701:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5702:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5703: }
1.126     brouard  5704: 
                   5705: /*********** Tricode ****************************/
1.220     brouard  5706:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5707:  {
                   5708:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5709:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5710:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5711:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5712:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5713:     */
1.130     brouard  5714: 
1.242     brouard  5715:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5716:    int modmaxcovj=0; /* Modality max of covariates j */
                   5717:    int cptcode=0; /* Modality max of covariates j */
                   5718:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5719: 
                   5720: 
1.242     brouard  5721:    /* cptcoveff=0;  */
                   5722:    /* *cptcov=0; */
1.126     brouard  5723:  
1.242     brouard  5724:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5725:    for (k=1; k <= maxncov; k++)
                   5726:      for(j=1; j<=2; j++)
                   5727:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5728: 
1.242     brouard  5729:    /* Loop on covariates without age and products and no quantitative variable */
                   5730:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5731:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5732:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5733:        switch(Fixed[k]) {
                   5734:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
1.311     brouard  5735:         modmaxcovj=0;
                   5736:         modmincovj=0;
1.242     brouard  5737:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5738:           ij=(int)(covar[Tvar[k]][i]);
                   5739:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5740:            * If product of Vn*Vm, still boolean *:
                   5741:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5742:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5743:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5744:              modality of the nth covariate of individual i. */
                   5745:           if (ij > modmaxcovj)
                   5746:             modmaxcovj=ij; 
                   5747:           else if (ij < modmincovj) 
                   5748:             modmincovj=ij; 
1.287     brouard  5749:           if (ij <0 || ij >1 ){
1.311     brouard  5750:             printf("ERROR, IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5751:             fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5752:             fflush(ficlog);
                   5753:             exit(1);
1.287     brouard  5754:           }
                   5755:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5756:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5757:             exit(1);
                   5758:           }else
                   5759:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5760:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5761:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5762:           /* getting the maximum value of the modality of the covariate
                   5763:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5764:              female ies 1, then modmaxcovj=1.
                   5765:           */
                   5766:         } /* end for loop on individuals i */
                   5767:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5768:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5769:         cptcode=modmaxcovj;
                   5770:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5771:         /*for (i=0; i<=cptcode; i++) {*/
                   5772:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5773:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5774:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5775:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5776:             if( j != -1){
                   5777:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5778:                                  covariate for which somebody answered excluding 
                   5779:                                  undefined. Usually 2: 0 and 1. */
                   5780:             }
                   5781:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5782:                                     covariate for which somebody answered including 
                   5783:                                     undefined. Usually 3: -1, 0 and 1. */
                   5784:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5785:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5786:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5787:                        
1.242     brouard  5788:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5789:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5790:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5791:         /* modmincovj=3; modmaxcovj = 7; */
                   5792:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5793:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5794:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5795:         /* nbcode[Tvar[j]][ij]=k; */
                   5796:         /* nbcode[Tvar[j]][1]=0; */
                   5797:         /* nbcode[Tvar[j]][2]=1; */
                   5798:         /* nbcode[Tvar[j]][3]=2; */
                   5799:         /* To be continued (not working yet). */
                   5800:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5801: 
                   5802:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5803:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5804:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5805:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5806:         /*, could be restored in the future */
                   5807:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5808:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5809:             break;
                   5810:           }
                   5811:           ij++;
1.287     brouard  5812:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5813:           cptcode = ij; /* New max modality for covar j */
                   5814:         } /* end of loop on modality i=-1 to 1 or more */
                   5815:         break;
                   5816:        case 1: /* Testing on varying covariate, could be simple and
                   5817:                * should look at waves or product of fixed *
                   5818:                * varying. No time to test -1, assuming 0 and 1 only */
                   5819:         ij=0;
                   5820:         for(i=0; i<=1;i++){
                   5821:           nbcode[Tvar[k]][++ij]=i;
                   5822:         }
                   5823:         break;
                   5824:        default:
                   5825:         break;
                   5826:        } /* end switch */
                   5827:      } /* end dummy test */
1.311     brouard  5828:      if(Dummy[k]==1 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5829:        for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5830:         if(isnan(covar[Tvar[k]][i])){
                   5831:           printf("ERROR, IMaCh doesn't treat fixed quantitative covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5832:           fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5833:           fflush(ficlog);
                   5834:           exit(1);
                   5835:          }
                   5836:        }
                   5837:      }
1.287     brouard  5838:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5839:   
                   5840:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5841:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5842:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5843:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5844:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5845:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5846:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5847:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5848:   
                   5849:    ij=0;
                   5850:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5851:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5852:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5853:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5854:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5855:        /* If product not in single variable we don't print results */
                   5856:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5857:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5858:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5859:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5860:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5861:        if(Fixed[k]!=0)
                   5862:         anyvaryingduminmodel=1;
                   5863:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5864:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5865:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5866:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5867:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5868:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5869:      } 
                   5870:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5871:    /* ij--; */
                   5872:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5873:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5874:                * because they can be excluded from the model and real
                   5875:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5876:    for(j=ij+1; j<= cptcovt; j++){
                   5877:      Tvaraff[j]=0;
                   5878:      Tmodelind[j]=0;
                   5879:    }
                   5880:    for(j=ntveff+1; j<= cptcovt; j++){
                   5881:      TmodelInvind[j]=0;
                   5882:    }
                   5883:    /* To be sorted */
                   5884:    ;
                   5885:  }
1.126     brouard  5886: 
1.145     brouard  5887: 
1.126     brouard  5888: /*********** Health Expectancies ****************/
                   5889: 
1.235     brouard  5890:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5891: 
                   5892: {
                   5893:   /* Health expectancies, no variances */
1.164     brouard  5894:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5895:   int nhstepma, nstepma; /* Decreasing with age */
                   5896:   double age, agelim, hf;
                   5897:   double ***p3mat;
                   5898:   double eip;
                   5899: 
1.238     brouard  5900:   /* pstamp(ficreseij); */
1.126     brouard  5901:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5902:   fprintf(ficreseij,"# Age");
                   5903:   for(i=1; i<=nlstate;i++){
                   5904:     for(j=1; j<=nlstate;j++){
                   5905:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5906:     }
                   5907:     fprintf(ficreseij," e%1d. ",i);
                   5908:   }
                   5909:   fprintf(ficreseij,"\n");
                   5910: 
                   5911:   
                   5912:   if(estepm < stepm){
                   5913:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5914:   }
                   5915:   else  hstepm=estepm;   
                   5916:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5917:    * This is mainly to measure the difference between two models: for example
                   5918:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5919:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5920:    * progression in between and thus overestimating or underestimating according
                   5921:    * to the curvature of the survival function. If, for the same date, we 
                   5922:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5923:    * to compare the new estimate of Life expectancy with the same linear 
                   5924:    * hypothesis. A more precise result, taking into account a more precise
                   5925:    * curvature will be obtained if estepm is as small as stepm. */
                   5926: 
                   5927:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5928:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5929:      nhstepm is the number of hstepm from age to agelim 
                   5930:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5931:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5932:      and note for a fixed period like estepm months */
                   5933:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5934:      survival function given by stepm (the optimization length). Unfortunately it
                   5935:      means that if the survival funtion is printed only each two years of age and if
                   5936:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5937:      results. So we changed our mind and took the option of the best precision.
                   5938:   */
                   5939:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5940: 
                   5941:   agelim=AGESUP;
                   5942:   /* If stepm=6 months */
                   5943:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5944:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5945:     
                   5946: /* nhstepm age range expressed in number of stepm */
                   5947:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5948:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5949:   /* if (stepm >= YEARM) hstepm=1;*/
                   5950:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5951:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5952: 
                   5953:   for (age=bage; age<=fage; age ++){ 
                   5954:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5955:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5956:     /* if (stepm >= YEARM) hstepm=1;*/
                   5957:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5958: 
                   5959:     /* If stepm=6 months */
                   5960:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5961:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5962:     
1.235     brouard  5963:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5964:     
                   5965:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5966:     
                   5967:     printf("%d|",(int)age);fflush(stdout);
                   5968:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5969:     
                   5970:     /* Computing expectancies */
                   5971:     for(i=1; i<=nlstate;i++)
                   5972:       for(j=1; j<=nlstate;j++)
                   5973:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5974:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5975:          
                   5976:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5977: 
                   5978:        }
                   5979: 
                   5980:     fprintf(ficreseij,"%3.0f",age );
                   5981:     for(i=1; i<=nlstate;i++){
                   5982:       eip=0;
                   5983:       for(j=1; j<=nlstate;j++){
                   5984:        eip +=eij[i][j][(int)age];
                   5985:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5986:       }
                   5987:       fprintf(ficreseij,"%9.4f", eip );
                   5988:     }
                   5989:     fprintf(ficreseij,"\n");
                   5990:     
                   5991:   }
                   5992:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5993:   printf("\n");
                   5994:   fprintf(ficlog,"\n");
                   5995:   
                   5996: }
                   5997: 
1.235     brouard  5998:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5999: 
                   6000: {
                   6001:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  6002:      to initial status i, ei. .
1.126     brouard  6003:   */
                   6004:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   6005:   int nhstepma, nstepma; /* Decreasing with age */
                   6006:   double age, agelim, hf;
                   6007:   double ***p3matp, ***p3matm, ***varhe;
                   6008:   double **dnewm,**doldm;
                   6009:   double *xp, *xm;
                   6010:   double **gp, **gm;
                   6011:   double ***gradg, ***trgradg;
                   6012:   int theta;
                   6013: 
                   6014:   double eip, vip;
                   6015: 
                   6016:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   6017:   xp=vector(1,npar);
                   6018:   xm=vector(1,npar);
                   6019:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   6020:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   6021:   
                   6022:   pstamp(ficresstdeij);
                   6023:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   6024:   fprintf(ficresstdeij,"# Age");
                   6025:   for(i=1; i<=nlstate;i++){
                   6026:     for(j=1; j<=nlstate;j++)
                   6027:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   6028:     fprintf(ficresstdeij," e%1d. ",i);
                   6029:   }
                   6030:   fprintf(ficresstdeij,"\n");
                   6031: 
                   6032:   pstamp(ficrescveij);
                   6033:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   6034:   fprintf(ficrescveij,"# Age");
                   6035:   for(i=1; i<=nlstate;i++)
                   6036:     for(j=1; j<=nlstate;j++){
                   6037:       cptj= (j-1)*nlstate+i;
                   6038:       for(i2=1; i2<=nlstate;i2++)
                   6039:        for(j2=1; j2<=nlstate;j2++){
                   6040:          cptj2= (j2-1)*nlstate+i2;
                   6041:          if(cptj2 <= cptj)
                   6042:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   6043:        }
                   6044:     }
                   6045:   fprintf(ficrescveij,"\n");
                   6046:   
                   6047:   if(estepm < stepm){
                   6048:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   6049:   }
                   6050:   else  hstepm=estepm;   
                   6051:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   6052:    * This is mainly to measure the difference between two models: for example
                   6053:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   6054:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   6055:    * progression in between and thus overestimating or underestimating according
                   6056:    * to the curvature of the survival function. If, for the same date, we 
                   6057:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   6058:    * to compare the new estimate of Life expectancy with the same linear 
                   6059:    * hypothesis. A more precise result, taking into account a more precise
                   6060:    * curvature will be obtained if estepm is as small as stepm. */
                   6061: 
                   6062:   /* For example we decided to compute the life expectancy with the smallest unit */
                   6063:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6064:      nhstepm is the number of hstepm from age to agelim 
                   6065:      nstepm is the number of stepm from age to agelin. 
                   6066:      Look at hpijx to understand the reason of that which relies in memory size
                   6067:      and note for a fixed period like estepm months */
                   6068:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   6069:      survival function given by stepm (the optimization length). Unfortunately it
                   6070:      means that if the survival funtion is printed only each two years of age and if
                   6071:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6072:      results. So we changed our mind and took the option of the best precision.
                   6073:   */
                   6074:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6075: 
                   6076:   /* If stepm=6 months */
                   6077:   /* nhstepm age range expressed in number of stepm */
                   6078:   agelim=AGESUP;
                   6079:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   6080:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   6081:   /* if (stepm >= YEARM) hstepm=1;*/
                   6082:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6083:   
                   6084:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6085:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6086:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   6087:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   6088:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   6089:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   6090: 
                   6091:   for (age=bage; age<=fage; age ++){ 
                   6092:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   6093:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   6094:     /* if (stepm >= YEARM) hstepm=1;*/
                   6095:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  6096:                
1.126     brouard  6097:     /* If stepm=6 months */
                   6098:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   6099:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   6100:     
                   6101:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  6102:                
1.126     brouard  6103:     /* Computing  Variances of health expectancies */
                   6104:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   6105:        decrease memory allocation */
                   6106:     for(theta=1; theta <=npar; theta++){
                   6107:       for(i=1; i<=npar; i++){ 
1.222     brouard  6108:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6109:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  6110:       }
1.235     brouard  6111:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   6112:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  6113:                        
1.126     brouard  6114:       for(j=1; j<= nlstate; j++){
1.222     brouard  6115:        for(i=1; i<=nlstate; i++){
                   6116:          for(h=0; h<=nhstepm-1; h++){
                   6117:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   6118:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   6119:          }
                   6120:        }
1.126     brouard  6121:       }
1.218     brouard  6122:                        
1.126     brouard  6123:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  6124:        for(h=0; h<=nhstepm-1; h++){
                   6125:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   6126:        }
1.126     brouard  6127:     }/* End theta */
                   6128:     
                   6129:     
                   6130:     for(h=0; h<=nhstepm-1; h++)
                   6131:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  6132:        for(theta=1; theta <=npar; theta++)
                   6133:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  6134:     
1.218     brouard  6135:                
1.222     brouard  6136:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  6137:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  6138:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  6139:                
1.222     brouard  6140:     printf("%d|",(int)age);fflush(stdout);
                   6141:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   6142:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  6143:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  6144:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   6145:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   6146:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   6147:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   6148:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  6149:       }
                   6150:     }
1.320     brouard  6151:     /* if((int)age ==50){ */
                   6152:     /*   printf(" age=%d cij=%d nres=%d varhe[%d][%d]=%f ",(int)age, cij, nres, 1,2,varhe[1][2]); */
                   6153:     /* } */
1.126     brouard  6154:     /* Computing expectancies */
1.235     brouard  6155:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  6156:     for(i=1; i<=nlstate;i++)
                   6157:       for(j=1; j<=nlstate;j++)
1.222     brouard  6158:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   6159:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  6160:                                        
1.222     brouard  6161:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  6162:                                        
1.222     brouard  6163:        }
1.269     brouard  6164: 
                   6165:     /* Standard deviation of expectancies ij */                
1.126     brouard  6166:     fprintf(ficresstdeij,"%3.0f",age );
                   6167:     for(i=1; i<=nlstate;i++){
                   6168:       eip=0.;
                   6169:       vip=0.;
                   6170:       for(j=1; j<=nlstate;j++){
1.222     brouard  6171:        eip += eij[i][j][(int)age];
                   6172:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   6173:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   6174:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  6175:       }
                   6176:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   6177:     }
                   6178:     fprintf(ficresstdeij,"\n");
1.218     brouard  6179:                
1.269     brouard  6180:     /* Variance of expectancies ij */          
1.126     brouard  6181:     fprintf(ficrescveij,"%3.0f",age );
                   6182:     for(i=1; i<=nlstate;i++)
                   6183:       for(j=1; j<=nlstate;j++){
1.222     brouard  6184:        cptj= (j-1)*nlstate+i;
                   6185:        for(i2=1; i2<=nlstate;i2++)
                   6186:          for(j2=1; j2<=nlstate;j2++){
                   6187:            cptj2= (j2-1)*nlstate+i2;
                   6188:            if(cptj2 <= cptj)
                   6189:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   6190:          }
1.126     brouard  6191:       }
                   6192:     fprintf(ficrescveij,"\n");
1.218     brouard  6193:                
1.126     brouard  6194:   }
                   6195:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   6196:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   6197:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   6198:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   6199:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6200:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6201:   printf("\n");
                   6202:   fprintf(ficlog,"\n");
1.218     brouard  6203:        
1.126     brouard  6204:   free_vector(xm,1,npar);
                   6205:   free_vector(xp,1,npar);
                   6206:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   6207:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   6208:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   6209: }
1.218     brouard  6210:  
1.126     brouard  6211: /************ Variance ******************/
1.235     brouard  6212:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  6213:  {
1.279     brouard  6214:    /** Variance of health expectancies 
                   6215:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   6216:     * double **newm;
                   6217:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   6218:     */
1.218     brouard  6219:   
                   6220:    /* int movingaverage(); */
                   6221:    double **dnewm,**doldm;
                   6222:    double **dnewmp,**doldmp;
                   6223:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  6224:    int first=0;
1.218     brouard  6225:    int k;
                   6226:    double *xp;
1.279     brouard  6227:    double **gp, **gm;  /**< for var eij */
                   6228:    double ***gradg, ***trgradg; /**< for var eij */
                   6229:    double **gradgp, **trgradgp; /**< for var p point j */
                   6230:    double *gpp, *gmp; /**< for var p point j */
                   6231:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  6232:    double ***p3mat;
                   6233:    double age,agelim, hf;
                   6234:    /* double ***mobaverage; */
                   6235:    int theta;
                   6236:    char digit[4];
                   6237:    char digitp[25];
                   6238: 
                   6239:    char fileresprobmorprev[FILENAMELENGTH];
                   6240: 
                   6241:    if(popbased==1){
                   6242:      if(mobilav!=0)
                   6243:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   6244:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   6245:    }
                   6246:    else 
                   6247:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  6248: 
1.218     brouard  6249:    /* if (mobilav!=0) { */
                   6250:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6251:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   6252:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   6253:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   6254:    /*   } */
                   6255:    /* } */
                   6256: 
                   6257:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   6258:    sprintf(digit,"%-d",ij);
                   6259:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   6260:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   6261:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   6262:    strcat(fileresprobmorprev,fileresu);
                   6263:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   6264:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   6265:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   6266:    }
                   6267:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6268:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6269:    pstamp(ficresprobmorprev);
                   6270:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  6271:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   6272:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   6273:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   6274:    }
                   6275:    for(j=1;j<=cptcoveff;j++) 
                   6276:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   6277:    fprintf(ficresprobmorprev,"\n");
                   6278: 
1.218     brouard  6279:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   6280:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6281:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   6282:      for(i=1; i<=nlstate;i++)
                   6283:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   6284:    }  
                   6285:    fprintf(ficresprobmorprev,"\n");
                   6286:   
                   6287:    fprintf(ficgp,"\n# Routine varevsij");
                   6288:    fprintf(ficgp,"\nunset title \n");
                   6289:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   6290:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   6291:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  6292: 
1.218     brouard  6293:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6294:    pstamp(ficresvij);
                   6295:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   6296:    if(popbased==1)
                   6297:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   6298:    else
                   6299:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   6300:    fprintf(ficresvij,"# Age");
                   6301:    for(i=1; i<=nlstate;i++)
                   6302:      for(j=1; j<=nlstate;j++)
                   6303:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   6304:    fprintf(ficresvij,"\n");
                   6305: 
                   6306:    xp=vector(1,npar);
                   6307:    dnewm=matrix(1,nlstate,1,npar);
                   6308:    doldm=matrix(1,nlstate,1,nlstate);
                   6309:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   6310:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6311: 
                   6312:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   6313:    gpp=vector(nlstate+1,nlstate+ndeath);
                   6314:    gmp=vector(nlstate+1,nlstate+ndeath);
                   6315:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  6316:   
1.218     brouard  6317:    if(estepm < stepm){
                   6318:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   6319:    }
                   6320:    else  hstepm=estepm;   
                   6321:    /* For example we decided to compute the life expectancy with the smallest unit */
                   6322:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6323:       nhstepm is the number of hstepm from age to agelim 
                   6324:       nstepm is the number of stepm from age to agelim. 
                   6325:       Look at function hpijx to understand why because of memory size limitations, 
                   6326:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   6327:       survival function given by stepm (the optimization length). Unfortunately it
                   6328:       means that if the survival funtion is printed every two years of age and if
                   6329:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6330:       results. So we changed our mind and took the option of the best precision.
                   6331:    */
                   6332:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6333:    agelim = AGESUP;
                   6334:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6335:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6336:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6337:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6338:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   6339:      gp=matrix(0,nhstepm,1,nlstate);
                   6340:      gm=matrix(0,nhstepm,1,nlstate);
                   6341:                
                   6342:                
                   6343:      for(theta=1; theta <=npar; theta++){
                   6344:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   6345:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6346:        }
1.279     brouard  6347:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   6348:        * returns into prlim .
1.288     brouard  6349:        */
1.242     brouard  6350:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  6351: 
                   6352:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  6353:        if (popbased==1) {
                   6354:         if(mobilav ==0){
                   6355:           for(i=1; i<=nlstate;i++)
                   6356:             prlim[i][i]=probs[(int)age][i][ij];
                   6357:         }else{ /* mobilav */ 
                   6358:           for(i=1; i<=nlstate;i++)
                   6359:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6360:         }
                   6361:        }
1.295     brouard  6362:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}x\f$ at horizon h.
1.279     brouard  6363:        */                      
                   6364:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
1.292     brouard  6365:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}x\f$, which are the probability
1.279     brouard  6366:        * at horizon h in state j including mortality.
                   6367:        */
1.218     brouard  6368:        for(j=1; j<= nlstate; j++){
                   6369:         for(h=0; h<=nhstepm; h++){
                   6370:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6371:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6372:         }
                   6373:        }
1.279     brouard  6374:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6375:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6376:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6377:        */
                   6378:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6379:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6380:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6381:        }
                   6382:        
                   6383:        /* Again with minus shift */
1.218     brouard  6384:                        
                   6385:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6386:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6387: 
1.242     brouard  6388:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6389:                        
                   6390:        if (popbased==1) {
                   6391:         if(mobilav ==0){
                   6392:           for(i=1; i<=nlstate;i++)
                   6393:             prlim[i][i]=probs[(int)age][i][ij];
                   6394:         }else{ /* mobilav */ 
                   6395:           for(i=1; i<=nlstate;i++)
                   6396:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6397:         }
                   6398:        }
                   6399:                        
1.235     brouard  6400:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6401:                        
                   6402:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6403:         for(h=0; h<=nhstepm; h++){
                   6404:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6405:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6406:         }
                   6407:        }
                   6408:        /* This for computing probability of death (h=1 means
                   6409:          computed over hstepm matrices product = hstepm*stepm months) 
                   6410:          as a weighted average of prlim.
                   6411:        */
                   6412:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6413:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6414:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6415:        }    
1.279     brouard  6416:        /* end shifting computations */
                   6417: 
                   6418:        /**< Computing gradient matrix at horizon h 
                   6419:        */
1.218     brouard  6420:        for(j=1; j<= nlstate; j++) /* vareij */
                   6421:         for(h=0; h<=nhstepm; h++){
                   6422:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6423:         }
1.279     brouard  6424:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6425:        */
                   6426:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6427:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6428:        }
                   6429:                        
                   6430:      } /* End theta */
1.279     brouard  6431:      
                   6432:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6433:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6434:                
                   6435:      for(h=0; h<=nhstepm; h++) /* veij */
                   6436:        for(j=1; j<=nlstate;j++)
                   6437:         for(theta=1; theta <=npar; theta++)
                   6438:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6439:                
                   6440:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6441:        for(theta=1; theta <=npar; theta++)
                   6442:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6443:      /**< as well as its transposed matrix 
                   6444:       */               
1.218     brouard  6445:                
                   6446:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6447:      for(i=1;i<=nlstate;i++)
                   6448:        for(j=1;j<=nlstate;j++)
                   6449:         vareij[i][j][(int)age] =0.;
1.279     brouard  6450: 
                   6451:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6452:       * and k (nhstepm) formula 15 of article
                   6453:       * Lievre-Brouard-Heathcote
                   6454:       */
                   6455:      
1.218     brouard  6456:      for(h=0;h<=nhstepm;h++){
                   6457:        for(k=0;k<=nhstepm;k++){
                   6458:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6459:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6460:         for(i=1;i<=nlstate;i++)
                   6461:           for(j=1;j<=nlstate;j++)
                   6462:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6463:        }
                   6464:      }
                   6465:                
1.279     brouard  6466:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6467:       * p.j overall mortality formula 49 but computed directly because
                   6468:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6469:       * wix is independent of theta.
                   6470:       */
1.218     brouard  6471:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6472:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6473:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6474:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6475:         varppt[j][i]=doldmp[j][i];
                   6476:      /* end ppptj */
                   6477:      /*  x centered again */
                   6478:                
1.242     brouard  6479:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6480:                
                   6481:      if (popbased==1) {
                   6482:        if(mobilav ==0){
                   6483:         for(i=1; i<=nlstate;i++)
                   6484:           prlim[i][i]=probs[(int)age][i][ij];
                   6485:        }else{ /* mobilav */ 
                   6486:         for(i=1; i<=nlstate;i++)
                   6487:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6488:        }
                   6489:      }
                   6490:                
                   6491:      /* This for computing probability of death (h=1 means
                   6492:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6493:        as a weighted average of prlim.
                   6494:      */
1.235     brouard  6495:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6496:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6497:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6498:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6499:      }    
                   6500:      /* end probability of death */
                   6501:                
                   6502:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6503:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6504:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6505:        for(i=1; i<=nlstate;i++){
                   6506:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6507:        }
                   6508:      } 
                   6509:      fprintf(ficresprobmorprev,"\n");
                   6510:                
                   6511:      fprintf(ficresvij,"%.0f ",age );
                   6512:      for(i=1; i<=nlstate;i++)
                   6513:        for(j=1; j<=nlstate;j++){
                   6514:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6515:        }
                   6516:      fprintf(ficresvij,"\n");
                   6517:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6518:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6519:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6520:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6521:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6522:    } /* End age */
                   6523:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6524:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6525:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6526:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6527:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6528:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6529:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6530:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6531:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6532:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6533:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6534:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6535:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6536:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6537:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6538:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6539:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6540:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6541:     */
1.218     brouard  6542:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6543:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6544: 
1.218     brouard  6545:    free_vector(xp,1,npar);
                   6546:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6547:    free_matrix(dnewm,1,nlstate,1,npar);
                   6548:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6549:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6550:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6551:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6552:    fclose(ficresprobmorprev);
                   6553:    fflush(ficgp);
                   6554:    fflush(fichtm); 
                   6555:  }  /* end varevsij */
1.126     brouard  6556: 
                   6557: /************ Variance of prevlim ******************/
1.269     brouard  6558:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6559: {
1.205     brouard  6560:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6561:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6562: 
1.268     brouard  6563:   double **dnewmpar,**doldm;
1.126     brouard  6564:   int i, j, nhstepm, hstepm;
                   6565:   double *xp;
                   6566:   double *gp, *gm;
                   6567:   double **gradg, **trgradg;
1.208     brouard  6568:   double **mgm, **mgp;
1.126     brouard  6569:   double age,agelim;
                   6570:   int theta;
                   6571:   
                   6572:   pstamp(ficresvpl);
1.288     brouard  6573:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6574:   fprintf(ficresvpl,"# Age ");
                   6575:   if(nresult >=1)
                   6576:     fprintf(ficresvpl," Result# ");
1.126     brouard  6577:   for(i=1; i<=nlstate;i++)
                   6578:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6579:   fprintf(ficresvpl,"\n");
                   6580: 
                   6581:   xp=vector(1,npar);
1.268     brouard  6582:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6583:   doldm=matrix(1,nlstate,1,nlstate);
                   6584:   
                   6585:   hstepm=1*YEARM; /* Every year of age */
                   6586:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6587:   agelim = AGESUP;
                   6588:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6589:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6590:     if (stepm >= YEARM) hstepm=1;
                   6591:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6592:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6593:     mgp=matrix(1,npar,1,nlstate);
                   6594:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6595:     gp=vector(1,nlstate);
                   6596:     gm=vector(1,nlstate);
                   6597: 
                   6598:     for(theta=1; theta <=npar; theta++){
                   6599:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6600:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6601:       }
1.288     brouard  6602:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6603:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6604:       /* else */
                   6605:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6606:       for(i=1;i<=nlstate;i++){
1.126     brouard  6607:        gp[i] = prlim[i][i];
1.208     brouard  6608:        mgp[theta][i] = prlim[i][i];
                   6609:       }
1.126     brouard  6610:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6611:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6612:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6613:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6614:       /* else */
                   6615:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6616:       for(i=1;i<=nlstate;i++){
1.126     brouard  6617:        gm[i] = prlim[i][i];
1.208     brouard  6618:        mgm[theta][i] = prlim[i][i];
                   6619:       }
1.126     brouard  6620:       for(i=1;i<=nlstate;i++)
                   6621:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6622:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6623:     } /* End theta */
                   6624: 
                   6625:     trgradg =matrix(1,nlstate,1,npar);
                   6626: 
                   6627:     for(j=1; j<=nlstate;j++)
                   6628:       for(theta=1; theta <=npar; theta++)
                   6629:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6630:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6631:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6632:     /*   for(j=1; j<=nlstate;j++){ */
                   6633:     /*         printf(" %d ",j); */
                   6634:     /*         for(theta=1; theta <=npar; theta++) */
                   6635:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6636:     /*         printf("\n "); */
                   6637:     /*   } */
                   6638:     /* } */
                   6639:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6640:     /*   printf("\n gradg %d ",(int)age); */
                   6641:     /*   for(j=1; j<=nlstate;j++){ */
                   6642:     /*         printf("%d ",j); */
                   6643:     /*         for(theta=1; theta <=npar; theta++) */
                   6644:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6645:     /*         printf("\n "); */
                   6646:     /*   } */
                   6647:     /* } */
1.126     brouard  6648: 
                   6649:     for(i=1;i<=nlstate;i++)
                   6650:       varpl[i][(int)age] =0.;
1.209     brouard  6651:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6652:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6653:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6654:     }else{
1.268     brouard  6655:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6656:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6657:     }
1.126     brouard  6658:     for(i=1;i<=nlstate;i++)
                   6659:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6660: 
                   6661:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6662:     if(nresult >=1)
                   6663:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6664:     for(i=1; i<=nlstate;i++){
1.126     brouard  6665:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6666:       /* for(j=1;j<=nlstate;j++) */
                   6667:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6668:     }
1.126     brouard  6669:     fprintf(ficresvpl,"\n");
                   6670:     free_vector(gp,1,nlstate);
                   6671:     free_vector(gm,1,nlstate);
1.208     brouard  6672:     free_matrix(mgm,1,npar,1,nlstate);
                   6673:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6674:     free_matrix(gradg,1,npar,1,nlstate);
                   6675:     free_matrix(trgradg,1,nlstate,1,npar);
                   6676:   } /* End age */
                   6677: 
                   6678:   free_vector(xp,1,npar);
                   6679:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6680:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6681: 
                   6682: }
                   6683: 
                   6684: 
                   6685: /************ Variance of backprevalence limit ******************/
1.269     brouard  6686:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6687: {
                   6688:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6689:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6690: 
                   6691:   double **dnewmpar,**doldm;
                   6692:   int i, j, nhstepm, hstepm;
                   6693:   double *xp;
                   6694:   double *gp, *gm;
                   6695:   double **gradg, **trgradg;
                   6696:   double **mgm, **mgp;
                   6697:   double age,agelim;
                   6698:   int theta;
                   6699:   
                   6700:   pstamp(ficresvbl);
                   6701:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6702:   fprintf(ficresvbl,"# Age ");
                   6703:   if(nresult >=1)
                   6704:     fprintf(ficresvbl," Result# ");
                   6705:   for(i=1; i<=nlstate;i++)
                   6706:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6707:   fprintf(ficresvbl,"\n");
                   6708: 
                   6709:   xp=vector(1,npar);
                   6710:   dnewmpar=matrix(1,nlstate,1,npar);
                   6711:   doldm=matrix(1,nlstate,1,nlstate);
                   6712:   
                   6713:   hstepm=1*YEARM; /* Every year of age */
                   6714:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6715:   agelim = AGEINF;
                   6716:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6717:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6718:     if (stepm >= YEARM) hstepm=1;
                   6719:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6720:     gradg=matrix(1,npar,1,nlstate);
                   6721:     mgp=matrix(1,npar,1,nlstate);
                   6722:     mgm=matrix(1,npar,1,nlstate);
                   6723:     gp=vector(1,nlstate);
                   6724:     gm=vector(1,nlstate);
                   6725: 
                   6726:     for(theta=1; theta <=npar; theta++){
                   6727:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6728:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6729:       }
                   6730:       if(mobilavproj > 0 )
                   6731:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6732:       else
                   6733:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6734:       for(i=1;i<=nlstate;i++){
                   6735:        gp[i] = bprlim[i][i];
                   6736:        mgp[theta][i] = bprlim[i][i];
                   6737:       }
                   6738:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6739:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6740:        if(mobilavproj > 0 )
                   6741:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6742:        else
                   6743:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6744:       for(i=1;i<=nlstate;i++){
                   6745:        gm[i] = bprlim[i][i];
                   6746:        mgm[theta][i] = bprlim[i][i];
                   6747:       }
                   6748:       for(i=1;i<=nlstate;i++)
                   6749:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6750:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6751:     } /* End theta */
                   6752: 
                   6753:     trgradg =matrix(1,nlstate,1,npar);
                   6754: 
                   6755:     for(j=1; j<=nlstate;j++)
                   6756:       for(theta=1; theta <=npar; theta++)
                   6757:        trgradg[j][theta]=gradg[theta][j];
                   6758:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6759:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6760:     /*   for(j=1; j<=nlstate;j++){ */
                   6761:     /*         printf(" %d ",j); */
                   6762:     /*         for(theta=1; theta <=npar; theta++) */
                   6763:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6764:     /*         printf("\n "); */
                   6765:     /*   } */
                   6766:     /* } */
                   6767:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6768:     /*   printf("\n gradg %d ",(int)age); */
                   6769:     /*   for(j=1; j<=nlstate;j++){ */
                   6770:     /*         printf("%d ",j); */
                   6771:     /*         for(theta=1; theta <=npar; theta++) */
                   6772:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6773:     /*         printf("\n "); */
                   6774:     /*   } */
                   6775:     /* } */
                   6776: 
                   6777:     for(i=1;i<=nlstate;i++)
                   6778:       varbpl[i][(int)age] =0.;
                   6779:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6780:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6781:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6782:     }else{
                   6783:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6784:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6785:     }
                   6786:     for(i=1;i<=nlstate;i++)
                   6787:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6788: 
                   6789:     fprintf(ficresvbl,"%.0f ",age );
                   6790:     if(nresult >=1)
                   6791:       fprintf(ficresvbl,"%d ",nres );
                   6792:     for(i=1; i<=nlstate;i++)
                   6793:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6794:     fprintf(ficresvbl,"\n");
                   6795:     free_vector(gp,1,nlstate);
                   6796:     free_vector(gm,1,nlstate);
                   6797:     free_matrix(mgm,1,npar,1,nlstate);
                   6798:     free_matrix(mgp,1,npar,1,nlstate);
                   6799:     free_matrix(gradg,1,npar,1,nlstate);
                   6800:     free_matrix(trgradg,1,nlstate,1,npar);
                   6801:   } /* End age */
                   6802: 
                   6803:   free_vector(xp,1,npar);
                   6804:   free_matrix(doldm,1,nlstate,1,npar);
                   6805:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6806: 
                   6807: }
                   6808: 
                   6809: /************ Variance of one-step probabilities  ******************/
                   6810: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6811:  {
                   6812:    int i, j=0,  k1, l1, tj;
                   6813:    int k2, l2, j1,  z1;
                   6814:    int k=0, l;
                   6815:    int first=1, first1, first2;
                   6816:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6817:    double **dnewm,**doldm;
                   6818:    double *xp;
                   6819:    double *gp, *gm;
                   6820:    double **gradg, **trgradg;
                   6821:    double **mu;
                   6822:    double age, cov[NCOVMAX+1];
                   6823:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6824:    int theta;
                   6825:    char fileresprob[FILENAMELENGTH];
                   6826:    char fileresprobcov[FILENAMELENGTH];
                   6827:    char fileresprobcor[FILENAMELENGTH];
                   6828:    double ***varpij;
                   6829: 
                   6830:    strcpy(fileresprob,"PROB_"); 
                   6831:    strcat(fileresprob,fileres);
                   6832:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6833:      printf("Problem with resultfile: %s\n", fileresprob);
                   6834:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6835:    }
                   6836:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6837:    strcat(fileresprobcov,fileresu);
                   6838:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6839:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6840:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6841:    }
                   6842:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6843:    strcat(fileresprobcor,fileresu);
                   6844:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6845:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6846:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6847:    }
                   6848:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6849:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6850:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6851:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6852:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6853:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6854:    pstamp(ficresprob);
                   6855:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6856:    fprintf(ficresprob,"# Age");
                   6857:    pstamp(ficresprobcov);
                   6858:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6859:    fprintf(ficresprobcov,"# Age");
                   6860:    pstamp(ficresprobcor);
                   6861:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6862:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6863: 
                   6864: 
1.222     brouard  6865:    for(i=1; i<=nlstate;i++)
                   6866:      for(j=1; j<=(nlstate+ndeath);j++){
                   6867:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6868:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6869:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6870:      }  
                   6871:    /* fprintf(ficresprob,"\n");
                   6872:       fprintf(ficresprobcov,"\n");
                   6873:       fprintf(ficresprobcor,"\n");
                   6874:    */
                   6875:    xp=vector(1,npar);
                   6876:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6877:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6878:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6879:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6880:    first=1;
                   6881:    fprintf(ficgp,"\n# Routine varprob");
                   6882:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6883:    fprintf(fichtm,"\n");
                   6884: 
1.288     brouard  6885:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6886:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6887:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6888: and drawn. It helps understanding how is the covariance between two incidences.\
                   6889:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6890:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6891: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6892: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6893: standard deviations wide on each axis. <br>\
                   6894:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6895:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6896: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6897: 
1.222     brouard  6898:    cov[1]=1;
                   6899:    /* tj=cptcoveff; */
1.225     brouard  6900:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6901:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6902:    j1=0;
1.224     brouard  6903:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6904:      if  (cptcovn>0) {
                   6905:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6906:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6907:        fprintf(ficresprob, "**********\n#\n");
                   6908:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6909:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6910:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6911:                        
1.222     brouard  6912:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6913:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6914:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6915:                        
                   6916:                        
1.222     brouard  6917:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.319     brouard  6918:        /* for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]); */
                   6919:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtmcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6920:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6921:                        
1.222     brouard  6922:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6923:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6924:        fprintf(ficresprobcor, "**********\n#");    
                   6925:        if(invalidvarcomb[j1]){
                   6926:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6927:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6928:         continue;
                   6929:        }
                   6930:      }
                   6931:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6932:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6933:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6934:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6935:      for (age=bage; age<=fage; age ++){ 
                   6936:        cov[2]=age;
                   6937:        if(nagesqr==1)
                   6938:         cov[3]= age*age;
                   6939:        for (k=1; k<=cptcovn;k++) {
                   6940:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6941:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6942:                                                                    * 1  1 1 1 1
                   6943:                                                                    * 2  2 1 1 1
                   6944:                                                                    * 3  1 2 1 1
                   6945:                                                                    */
                   6946:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6947:        }
1.319     brouard  6948:        /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   6949:        /* ) p nbcode[Tvar[Tage[k]]][(1 & (ij-1) >> (k-1))+1] */
                   6950:        /*for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6951:        for (k=1; k<=cptcovage;k++)
                   6952:         cov[2+Tage[k]+nagesqr]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
1.222     brouard  6953:        for (k=1; k<=cptcovprod;k++)
                   6954:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6955:                        
                   6956:                        
1.222     brouard  6957:        for(theta=1; theta <=npar; theta++){
                   6958:         for(i=1; i<=npar; i++)
                   6959:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6960:                                
1.222     brouard  6961:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6962:                                
1.222     brouard  6963:         k=0;
                   6964:         for(i=1; i<= (nlstate); i++){
                   6965:           for(j=1; j<=(nlstate+ndeath);j++){
                   6966:             k=k+1;
                   6967:             gp[k]=pmmij[i][j];
                   6968:           }
                   6969:         }
1.220     brouard  6970:                                
1.222     brouard  6971:         for(i=1; i<=npar; i++)
                   6972:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6973:                                
1.222     brouard  6974:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6975:         k=0;
                   6976:         for(i=1; i<=(nlstate); i++){
                   6977:           for(j=1; j<=(nlstate+ndeath);j++){
                   6978:             k=k+1;
                   6979:             gm[k]=pmmij[i][j];
                   6980:           }
                   6981:         }
1.220     brouard  6982:                                
1.222     brouard  6983:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6984:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6985:        }
1.126     brouard  6986: 
1.222     brouard  6987:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6988:         for(theta=1; theta <=npar; theta++)
                   6989:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6990:                        
1.222     brouard  6991:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6992:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6993:                        
1.222     brouard  6994:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6995:                        
1.222     brouard  6996:        k=0;
                   6997:        for(i=1; i<=(nlstate); i++){
                   6998:         for(j=1; j<=(nlstate+ndeath);j++){
                   6999:           k=k+1;
                   7000:           mu[k][(int) age]=pmmij[i][j];
                   7001:         }
                   7002:        }
                   7003:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   7004:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   7005:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  7006:                        
1.222     brouard  7007:        /*printf("\n%d ",(int)age);
                   7008:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   7009:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   7010:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   7011:         }*/
1.220     brouard  7012:                        
1.222     brouard  7013:        fprintf(ficresprob,"\n%d ",(int)age);
                   7014:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   7015:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  7016:                        
1.222     brouard  7017:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   7018:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   7019:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   7020:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   7021:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   7022:        }
                   7023:        i=0;
                   7024:        for (k=1; k<=(nlstate);k++){
                   7025:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   7026:           i++;
                   7027:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   7028:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   7029:           for (j=1; j<=i;j++){
                   7030:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   7031:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   7032:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   7033:           }
                   7034:         }
                   7035:        }/* end of loop for state */
                   7036:      } /* end of loop for age */
                   7037:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   7038:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   7039:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   7040:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   7041:     
                   7042:      /* Confidence intervalle of pij  */
                   7043:      /*
                   7044:        fprintf(ficgp,"\nunset parametric;unset label");
                   7045:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   7046:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   7047:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   7048:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   7049:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   7050:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   7051:      */
                   7052:                
                   7053:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   7054:      first1=1;first2=2;
                   7055:      for (k2=1; k2<=(nlstate);k2++){
                   7056:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   7057:         if(l2==k2) continue;
                   7058:         j=(k2-1)*(nlstate+ndeath)+l2;
                   7059:         for (k1=1; k1<=(nlstate);k1++){
                   7060:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   7061:             if(l1==k1) continue;
                   7062:             i=(k1-1)*(nlstate+ndeath)+l1;
                   7063:             if(i<=j) continue;
                   7064:             for (age=bage; age<=fage; age ++){ 
                   7065:               if ((int)age %5==0){
                   7066:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   7067:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   7068:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   7069:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   7070:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   7071:                 c12=cv12/sqrt(v1*v2);
                   7072:                 /* Computing eigen value of matrix of covariance */
                   7073:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   7074:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   7075:                 if ((lc2 <0) || (lc1 <0) ){
                   7076:                   if(first2==1){
                   7077:                     first1=0;
                   7078:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   7079:                   }
                   7080:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   7081:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   7082:                   /* lc2=fabs(lc2); */
                   7083:                 }
1.220     brouard  7084:                                                                
1.222     brouard  7085:                 /* Eigen vectors */
1.280     brouard  7086:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   7087:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   7088:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   7089:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   7090:                 }else
                   7091:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  7092:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   7093:                 v21=(lc1-v1)/cv12*v11;
                   7094:                 v12=-v21;
                   7095:                 v22=v11;
                   7096:                 tnalp=v21/v11;
                   7097:                 if(first1==1){
                   7098:                   first1=0;
                   7099:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   7100:                 }
                   7101:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   7102:                 /*printf(fignu*/
                   7103:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   7104:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   7105:                 if(first==1){
                   7106:                   first=0;
                   7107:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   7108:                   fprintf(ficgp,"\nset parametric;unset label");
                   7109:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   7110:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  7111:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  7112:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  7113: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  7114:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   7115:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7116:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7117:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   7118:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7119:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   7120:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   7121:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  7122:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   7123:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  7124:                 }else{
                   7125:                   first=0;
                   7126:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   7127:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   7128:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   7129:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  7130:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   7131:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  7132:                 }/* if first */
                   7133:               } /* age mod 5 */
                   7134:             } /* end loop age */
                   7135:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   7136:             first=1;
                   7137:           } /*l12 */
                   7138:         } /* k12 */
                   7139:        } /*l1 */
                   7140:      }/* k1 */
                   7141:    }  /* loop on combination of covariates j1 */
                   7142:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   7143:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   7144:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   7145:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   7146:    free_vector(xp,1,npar);
                   7147:    fclose(ficresprob);
                   7148:    fclose(ficresprobcov);
                   7149:    fclose(ficresprobcor);
                   7150:    fflush(ficgp);
                   7151:    fflush(fichtmcov);
                   7152:  }
1.126     brouard  7153: 
                   7154: 
                   7155: /******************* Printing html file ***********/
1.201     brouard  7156: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  7157:                  int lastpass, int stepm, int weightopt, char model[],\
                   7158:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.296     brouard  7159:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int prevbcast, int estepm , \
                   7160:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateprojd, double dateback1, \
                   7161:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateprojf, double dateback2){
1.237     brouard  7162:   int jj1, k1, i1, cpt, k4, nres;
1.319     brouard  7163:   /* In fact some results are already printed in fichtm which is open */
1.126     brouard  7164:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   7165:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   7166: </ul>");
1.319     brouard  7167: /*    fprintf(fichtm,"<ul><li> model=1+age+%s\n \ */
                   7168: /* </ul>", model); */
1.214     brouard  7169:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   7170:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   7171:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   7172:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  7173:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   7174:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  7175:    fprintf(fichtm,"\
                   7176:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  7177:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  7178:    fprintf(fichtm,"\
1.217     brouard  7179:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   7180:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   7181:    fprintf(fichtm,"\
1.288     brouard  7182:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  7183:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  7184:    fprintf(fichtm,"\
1.288     brouard  7185:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  7186:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   7187:    fprintf(fichtm,"\
1.211     brouard  7188:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  7189:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  7190:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  7191:    if(prevfcast==1){
                   7192:      fprintf(fichtm,"\
                   7193:  - Prevalence projections by age and states:                           \
1.201     brouard  7194:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  7195:    }
1.126     brouard  7196: 
                   7197: 
1.225     brouard  7198:    m=pow(2,cptcoveff);
1.222     brouard  7199:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7200: 
1.317     brouard  7201:    fprintf(fichtm," \n<ul><li><b>Graphs (first order)</b></li><p>");
1.264     brouard  7202: 
                   7203:    jj1=0;
                   7204: 
                   7205:    fprintf(fichtm," \n<ul>");
                   7206:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7207:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   7208:      if(m != 1 && TKresult[nres]!= k1)
                   7209:        continue;
                   7210:      jj1++;
                   7211:      if (cptcovn > 0) {
                   7212:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   7213:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7214:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7215:        }
                   7216:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7217:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7218:        }
                   7219:        fprintf(fichtm,"\">");
                   7220:        
                   7221:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   7222:        fprintf(fichtm,"************ Results for covariates");
                   7223:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7224:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7225:        }
                   7226:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7227:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7228:        }
                   7229:        if(invalidvarcomb[k1]){
                   7230:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   7231:         continue;
                   7232:        }
                   7233:        fprintf(fichtm,"</a></li>");
                   7234:      } /* cptcovn >0 */
                   7235:    }
1.317     brouard  7236:    fprintf(fichtm," \n</ul>");
1.264     brouard  7237: 
1.222     brouard  7238:    jj1=0;
1.237     brouard  7239: 
                   7240:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  7241:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  7242:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7243:        continue;
1.220     brouard  7244: 
1.222     brouard  7245:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7246:      jj1++;
                   7247:      if (cptcovn > 0) {
1.264     brouard  7248:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   7249:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7250:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7251:        }
                   7252:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7253:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7254:        }
                   7255:        fprintf(fichtm,"\"</a>");
                   7256:  
1.222     brouard  7257:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7258:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  7259:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7260:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   7261:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7262:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  7263:        }
1.237     brouard  7264:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7265:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7266:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   7267:       }
                   7268:        
1.230     brouard  7269:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.321     brouard  7270:        fprintf(fichtm," (model=%s) ************\n<hr size=\"2\" color=\"#EC5E5E\">",model);
1.222     brouard  7271:        if(invalidvarcomb[k1]){
                   7272:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   7273:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   7274:         continue;
                   7275:        }
                   7276:      }
                   7277:      /* aij, bij */
1.259     brouard  7278:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  7279: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  7280:      /* Pij */
1.241     brouard  7281:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   7282: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  7283:      /* Quasi-incidences */
                   7284:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  7285:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  7286:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  7287: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   7288: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  7289:      /* Survival functions (period) in state j */
                   7290:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7291:        fprintf(fichtm,"<br>\n- Survival functions in state %d. And probability to be observed in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7292: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  7293:      }
                   7294:      /* State specific survival functions (period) */
                   7295:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7296:        fprintf(fichtm,"<br>\n- Survival functions in state %d and in any other live state (total).\
                   7297:  And probability to be observed in various states (up to %d) being in state %d at different ages.      \
1.283     brouard  7298:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  7299:      }
1.288     brouard  7300:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  7301:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7302:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7303: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  7304:      }
1.296     brouard  7305:      if(prevbcast==1){
1.288     brouard  7306:        /* Backward prevalence in each health state */
1.222     brouard  7307:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7308:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7309: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  7310:        }
1.217     brouard  7311:      }
1.222     brouard  7312:      if(prevfcast==1){
1.288     brouard  7313:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  7314:        for(cpt=1; cpt<=nlstate;cpt++){
1.314     brouard  7315:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>", dateprev1, dateprev2, mobilavproj, dateprojd, dateprojf, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
                   7316:         fprintf(fichtm," (data from text file  <a href=\"%s.txt\">%s.txt</a>)\n<br>",subdirf2(optionfilefiname,"F_"),subdirf2(optionfilefiname,"F_"));
                   7317:         fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">",
                   7318:                 subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  7319:        }
                   7320:      }
1.296     brouard  7321:      if(prevbcast==1){
1.268     brouard  7322:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   7323:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  7324:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   7325:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   7326:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
1.314     brouard  7327: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7328:         fprintf(fichtm," (data from text file  <a href=\"%s.txt\">%s.txt</a>)\n<br>",subdirf2(optionfilefiname,"FB_"),subdirf2(optionfilefiname,"FB_"));
                   7329:         fprintf(fichtm," <img src=\"%s_%d-%d-%d.svg\">", subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  7330:        }
                   7331:      }
1.220     brouard  7332:         
1.222     brouard  7333:      for(cpt=1; cpt<=nlstate;cpt++) {
1.314     brouard  7334:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
                   7335:        fprintf(fichtm," (data from text file  <a href=\"%s.txt\"> %s.txt</a>)\n<br>",subdirf2(optionfilefiname,"E_"),subdirf2(optionfilefiname,"E_"));
                   7336:        fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">", subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres );
1.222     brouard  7337:      }
                   7338:      /* } /\* end i1 *\/ */
                   7339:    }/* End k1 */
                   7340:    fprintf(fichtm,"</ul>");
1.126     brouard  7341: 
1.222     brouard  7342:    fprintf(fichtm,"\
1.126     brouard  7343: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  7344:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  7345:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  7346: But because parameters are usually highly correlated (a higher incidence of disability \
                   7347: and a higher incidence of recovery can give very close observed transition) it might \
                   7348: be very useful to look not only at linear confidence intervals estimated from the \
                   7349: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   7350: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   7351: covariance matrix of the one-step probabilities. \
                   7352: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  7353: 
1.222     brouard  7354:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   7355:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   7356:    fprintf(fichtm,"\
1.126     brouard  7357:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7358:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  7359: 
1.222     brouard  7360:    fprintf(fichtm,"\
1.126     brouard  7361:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7362:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   7363:    fprintf(fichtm,"\
1.126     brouard  7364:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7365:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7366:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7367:    fprintf(fichtm,"\
1.126     brouard  7368:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7369:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7370:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7371:    fprintf(fichtm,"\
1.288     brouard  7372:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7373:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7374:    fprintf(fichtm,"\
1.128     brouard  7375:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7376:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7377:    fprintf(fichtm,"\
1.288     brouard  7378:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7379:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7380: 
                   7381: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7382: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7383: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7384: /*     <br>",fileres,fileres,fileres,fileres); */
                   7385: /*  else  */
                   7386: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7387:    fflush(fichtm);
1.126     brouard  7388: 
1.225     brouard  7389:    m=pow(2,cptcoveff);
1.222     brouard  7390:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7391: 
1.317     brouard  7392:    fprintf(fichtm," <ul><li><b>Graphs (second order)</b></li><p>");
                   7393: 
                   7394:   jj1=0;
                   7395: 
                   7396:    fprintf(fichtm," \n<ul>");
                   7397:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7398:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   7399:      if(m != 1 && TKresult[nres]!= k1)
                   7400:        continue;
                   7401:      jj1++;
                   7402:      if (cptcovn > 0) {
                   7403:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescovsecond");
                   7404:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7405:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7406:        }
                   7407:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7408:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7409:        }
                   7410:        fprintf(fichtm,"\">");
                   7411:        
                   7412:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   7413:        fprintf(fichtm,"************ Results for covariates");
                   7414:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7415:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7416:        }
                   7417:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7418:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7419:        }
                   7420:        if(invalidvarcomb[k1]){
                   7421:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   7422:         continue;
                   7423:        }
                   7424:        fprintf(fichtm,"</a></li>");
                   7425:      } /* cptcovn >0 */
                   7426:    }
                   7427:    fprintf(fichtm," \n</ul>");
                   7428: 
1.222     brouard  7429:    jj1=0;
1.237     brouard  7430: 
1.241     brouard  7431:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7432:    for(k1=1; k1<=m;k1++){
1.253     brouard  7433:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7434:        continue;
1.222     brouard  7435:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7436:      jj1++;
1.126     brouard  7437:      if (cptcovn > 0) {
1.317     brouard  7438:        fprintf(fichtm,"\n<p><a name=\"rescovsecond");
                   7439:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7440:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7441:        }
                   7442:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7443:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7444:        }
                   7445:        fprintf(fichtm,"\"</a>");
                   7446:        
1.126     brouard  7447:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.317     brouard  7448:        for (cpt=1; cpt<=cptcoveff;cpt++){  /**< cptcoveff number of variables */
1.237     brouard  7449:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
1.317     brouard  7450:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
1.237     brouard  7451:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
1.317     brouard  7452:        }
1.237     brouard  7453:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7454:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7455:       }
                   7456: 
1.321     brouard  7457:        fprintf(fichtm," (model=%s) ************\n<hr size=\"2\" color=\"#EC5E5E\">",model);
1.220     brouard  7458: 
1.222     brouard  7459:        if(invalidvarcomb[k1]){
                   7460:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7461:         continue;
                   7462:        }
1.126     brouard  7463:      }
                   7464:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7465:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.314     brouard  7466: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7467:        fprintf(fichtm," (data from text file  <a href=\"%s\">%s</a>)\n <br>",subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
                   7468:        fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">",subdirf2(optionfilefiname,"V_"), cpt,k1,nres);
1.126     brouard  7469:      }
                   7470:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.314     brouard  7471: health expectancies in each live states (1 to %d). If popbased=1 the smooth (due to the model) \
1.128     brouard  7472: true period expectancies (those weighted with period prevalences are also\
                   7473:  drawn in addition to the population based expectancies computed using\
1.314     brouard  7474:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>",nlstate, subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
                   7475:      fprintf(fichtm," (data from text file <a href=\"%s.txt\">%s.txt</a>) \n<br>",subdirf2(optionfilefiname,"T_"),subdirf2(optionfilefiname,"T_"));
                   7476:      fprintf(fichtm,"<img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7477:      /* } /\* end i1 *\/ */
                   7478:    }/* End k1 */
1.241     brouard  7479:   }/* End nres */
1.222     brouard  7480:    fprintf(fichtm,"</ul>");
                   7481:    fflush(fichtm);
1.126     brouard  7482: }
                   7483: 
                   7484: /******************* Gnuplot file **************/
1.296     brouard  7485: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int prevbcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7486: 
                   7487:   char dirfileres[132],optfileres[132];
1.264     brouard  7488:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7489:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7490:   int lv=0, vlv=0, kl=0;
1.130     brouard  7491:   int ng=0;
1.201     brouard  7492:   int vpopbased;
1.223     brouard  7493:   int ioffset; /* variable offset for columns */
1.270     brouard  7494:   int iyearc=1; /* variable column for year of projection  */
                   7495:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7496:   int nres=0; /* Index of resultline */
1.266     brouard  7497:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7498: 
1.126     brouard  7499: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7500: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7501: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7502: /*   } */
                   7503: 
                   7504:   /*#ifdef windows */
                   7505:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7506:   /*#endif */
1.225     brouard  7507:   m=pow(2,cptcoveff);
1.126     brouard  7508: 
1.274     brouard  7509:   /* diagram of the model */
                   7510:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7511:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7512:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7513:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7514: 
                   7515:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7516:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7517:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7518:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7519:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7520:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7521:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7522: 
1.202     brouard  7523:   /* Contribution to likelihood */
                   7524:   /* Plot the probability implied in the likelihood */
1.223     brouard  7525:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7526:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7527:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7528:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7529: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7530:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7531: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7532:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7533:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7534:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7535:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7536:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7537:   for (i=1; i<= nlstate ; i ++) {
                   7538:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7539:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7540:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7541:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7542:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7543:     }
                   7544:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7545:   }
                   7546:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7547:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7548:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7549:   fprintf(ficgp,"\nset out;unset log\n");
                   7550:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7551: 
1.126     brouard  7552:   strcpy(dirfileres,optionfilefiname);
                   7553:   strcpy(optfileres,"vpl");
1.223     brouard  7554:   /* 1eme*/
1.238     brouard  7555:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7556:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7557:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7558:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7559:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7560:          continue;
                   7561:        /* We are interested in selected combination by the resultline */
1.246     brouard  7562:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7563:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7564:        strcpy(gplotlabel,"(");
1.238     brouard  7565:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7566:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7567:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7568:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7569:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7570:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7571:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7572:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7573:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7574:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7575:        }
                   7576:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7577:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7578:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7579:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7580:        }
                   7581:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7582:        /* printf("\n#\n"); */
1.238     brouard  7583:        fprintf(ficgp,"\n#\n");
                   7584:        if(invalidvarcomb[k1]){
1.260     brouard  7585:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7586:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7587:          continue;
                   7588:        }
1.235     brouard  7589:       
1.241     brouard  7590:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7591:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7592:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
1.321     brouard  7593:        fprintf(ficgp,"set title \"Alive state %d %s model=%s\" font \"Helvetica,12\"\n",cpt,gplotlabel,model);
1.260     brouard  7594:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7595:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7596:       /* k1-1 error should be nres-1*/
1.238     brouard  7597:        for (i=1; i<= nlstate ; i ++) {
                   7598:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7599:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7600:        }
1.288     brouard  7601:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7602:        for (i=1; i<= nlstate ; i ++) {
                   7603:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7604:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7605:        } 
1.260     brouard  7606:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7607:        for (i=1; i<= nlstate ; i ++) {
                   7608:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7609:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7610:        }  
1.265     brouard  7611:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7612:        
                   7613:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7614:         if(cptcoveff ==0){
1.271     brouard  7615:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7616:        }else{
                   7617:          kl=0;
                   7618:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7619:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7620:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7621:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7622:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7623:            vlv= nbcode[Tvaraff[k]][lv];
                   7624:            kl++;
                   7625:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7626:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7627:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7628:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7629:            if(k==cptcoveff){
                   7630:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7631:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7632:            }else{
                   7633:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7634:              kl++;
                   7635:            }
                   7636:          } /* end covariate */
                   7637:        } /* end if no covariate */
                   7638: 
1.296     brouard  7639:        if(prevbcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
1.238     brouard  7640:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7641:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7642:          if(cptcoveff ==0){
1.245     brouard  7643:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7644:          }else{
                   7645:            kl=0;
                   7646:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7647:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7648:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7649:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7650:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7651:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7652:              kl++;
1.238     brouard  7653:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7654:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7655:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7656:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7657:              if(k==cptcoveff){
1.245     brouard  7658:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7659:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7660:              }else{
                   7661:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7662:                kl++;
                   7663:              }
                   7664:            } /* end covariate */
                   7665:          } /* end if no covariate */
1.296     brouard  7666:          if(prevbcast == 1){
1.268     brouard  7667:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7668:            /* k1-1 error should be nres-1*/
                   7669:            for (i=1; i<= nlstate ; i ++) {
                   7670:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7671:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7672:            }
1.271     brouard  7673:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7674:            for (i=1; i<= nlstate ; i ++) {
                   7675:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7676:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7677:            } 
1.276     brouard  7678:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7679:            for (i=1; i<= nlstate ; i ++) {
                   7680:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7681:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7682:            } 
1.274     brouard  7683:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7684:          } /* end if backprojcast */
1.296     brouard  7685:        } /* end if prevbcast */
1.276     brouard  7686:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7687:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7688:       } /* nres */
1.201     brouard  7689:     } /* k1 */
                   7690:   } /* cpt */
1.235     brouard  7691: 
                   7692:   
1.126     brouard  7693:   /*2 eme*/
1.238     brouard  7694:   for (k1=1; k1<= m ; k1 ++){  
                   7695:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7696:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7697:        continue;
                   7698:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7699:       strcpy(gplotlabel,"(");
1.238     brouard  7700:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7701:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7702:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7703:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7704:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7705:        vlv= nbcode[Tvaraff[k]][lv];
                   7706:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7707:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7708:       }
1.237     brouard  7709:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7710:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7711:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7712:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7713:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7714:       }
1.264     brouard  7715:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7716:       fprintf(ficgp,"\n#\n");
1.223     brouard  7717:       if(invalidvarcomb[k1]){
                   7718:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7719:        continue;
                   7720:       }
1.219     brouard  7721:                        
1.241     brouard  7722:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7723:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7724:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7725:        if(vpopbased==0){
1.238     brouard  7726:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7727:        }else
1.238     brouard  7728:          fprintf(ficgp,"\nreplot ");
                   7729:        for (i=1; i<= nlstate+1 ; i ++) {
                   7730:          k=2*i;
1.261     brouard  7731:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7732:          for (j=1; j<= nlstate+1 ; j ++) {
                   7733:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7734:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7735:          }   
                   7736:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7737:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7738:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7739:          for (j=1; j<= nlstate+1 ; j ++) {
                   7740:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7741:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7742:          }   
                   7743:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7744:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7745:          for (j=1; j<= nlstate+1 ; j ++) {
                   7746:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7747:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7748:          }   
                   7749:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7750:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7751:        } /* state */
                   7752:       } /* vpopbased */
1.264     brouard  7753:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7754:     } /* end nres */
                   7755:   } /* k1 end 2 eme*/
                   7756:        
                   7757:        
                   7758:   /*3eme*/
                   7759:   for (k1=1; k1<= m ; k1 ++){
                   7760:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7761:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7762:        continue;
                   7763: 
                   7764:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7765:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7766:        strcpy(gplotlabel,"(");
1.238     brouard  7767:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7768:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7769:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7770:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7771:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7772:          vlv= nbcode[Tvaraff[k]][lv];
                   7773:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7774:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7775:        }
                   7776:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7777:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7778:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7779:        }       
1.264     brouard  7780:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7781:        fprintf(ficgp,"\n#\n");
                   7782:        if(invalidvarcomb[k1]){
                   7783:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7784:          continue;
                   7785:        }
                   7786:                        
                   7787:        /*       k=2+nlstate*(2*cpt-2); */
                   7788:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7789:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7790:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7791:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7792: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7793:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7794:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7795:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7796:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7797:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7798:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7799:                                
1.238     brouard  7800:        */
                   7801:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7802:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7803:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7804:                                
1.238     brouard  7805:        } 
1.261     brouard  7806:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7807:       }
1.264     brouard  7808:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7809:     } /* end nres */
                   7810:   } /* end kl 3eme */
1.126     brouard  7811:   
1.223     brouard  7812:   /* 4eme */
1.201     brouard  7813:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7814:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7815:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7816:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7817:        continue;
1.238     brouard  7818:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7819:        strcpy(gplotlabel,"(");
1.238     brouard  7820:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7821:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7822:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7823:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7824:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7825:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7826:          vlv= nbcode[Tvaraff[k]][lv];
                   7827:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7828:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7829:        }
                   7830:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7831:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7832:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7833:        }       
1.264     brouard  7834:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7835:        fprintf(ficgp,"\n#\n");
                   7836:        if(invalidvarcomb[k1]){
                   7837:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7838:          continue;
1.223     brouard  7839:        }
1.238     brouard  7840:       
1.241     brouard  7841:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7842:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7843:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7844: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7845:        k=3;
                   7846:        for (i=1; i<= nlstate ; i ++){
                   7847:          if(i==1){
                   7848:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7849:          }else{
                   7850:            fprintf(ficgp,", '' ");
                   7851:          }
                   7852:          l=(nlstate+ndeath)*(i-1)+1;
                   7853:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7854:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7855:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7856:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7857:        } /* nlstate */
1.264     brouard  7858:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7859:       } /* end cpt state*/ 
                   7860:     } /* end nres */
                   7861:   } /* end covariate k1 */  
                   7862: 
1.220     brouard  7863: /* 5eme */
1.201     brouard  7864:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7865:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7866:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7867:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7868:        continue;
1.238     brouard  7869:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7870:        strcpy(gplotlabel,"(");
1.238     brouard  7871:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7872:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7873:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7874:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7875:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7876:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7877:          vlv= nbcode[Tvaraff[k]][lv];
                   7878:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7879:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7880:        }
                   7881:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7882:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7883:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7884:        }       
1.264     brouard  7885:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7886:        fprintf(ficgp,"\n#\n");
                   7887:        if(invalidvarcomb[k1]){
                   7888:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7889:          continue;
                   7890:        }
1.227     brouard  7891:       
1.241     brouard  7892:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7893:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7894:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7895: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7896:        k=3;
                   7897:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7898:          if(j==1)
                   7899:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7900:          else
                   7901:            fprintf(ficgp,", '' ");
                   7902:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7903:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7904:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7905:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7906:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7907:        } /* nlstate */
                   7908:        fprintf(ficgp,", '' ");
                   7909:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7910:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7911:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7912:          if(j < nlstate)
                   7913:            fprintf(ficgp,"$%d +",k+l);
                   7914:          else
                   7915:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7916:        }
1.264     brouard  7917:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7918:       } /* end cpt state*/ 
                   7919:     } /* end covariate */  
                   7920:   } /* end nres */
1.227     brouard  7921:   
1.220     brouard  7922: /* 6eme */
1.202     brouard  7923:   /* CV preval stable (period) for each covariate */
1.237     brouard  7924:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7925:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7926:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7927:       continue;
1.255     brouard  7928:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7929:       strcpy(gplotlabel,"(");      
1.288     brouard  7930:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7931:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7932:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7933:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7934:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7935:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7936:        vlv= nbcode[Tvaraff[k]][lv];
                   7937:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7938:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7939:       }
1.237     brouard  7940:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7941:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7942:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7943:       }        
1.264     brouard  7944:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7945:       fprintf(ficgp,"\n#\n");
1.223     brouard  7946:       if(invalidvarcomb[k1]){
1.227     brouard  7947:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7948:        continue;
1.223     brouard  7949:       }
1.227     brouard  7950:       
1.241     brouard  7951:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7952:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7953:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7954: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7955:       k=3; /* Offset */
1.255     brouard  7956:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7957:        if(i==1)
                   7958:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7959:        else
                   7960:          fprintf(ficgp,", '' ");
1.255     brouard  7961:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7962:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7963:        for (j=2; j<= nlstate ; j ++)
                   7964:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7965:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7966:       } /* nlstate */
1.264     brouard  7967:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7968:     } /* end cpt state*/ 
                   7969:   } /* end covariate */  
1.227     brouard  7970:   
                   7971:   
1.220     brouard  7972: /* 7eme */
1.296     brouard  7973:   if(prevbcast == 1){
1.288     brouard  7974:     /* CV backward prevalence  for each covariate */
1.237     brouard  7975:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7976:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7977:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7978:        continue;
1.268     brouard  7979:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7980:        strcpy(gplotlabel,"(");      
1.288     brouard  7981:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7982:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7983:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7984:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7985:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7986:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7987:          vlv= nbcode[Tvaraff[k]][lv];
                   7988:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7989:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7990:        }
1.237     brouard  7991:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7992:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7993:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7994:        }       
1.264     brouard  7995:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7996:        fprintf(ficgp,"\n#\n");
                   7997:        if(invalidvarcomb[k1]){
                   7998:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7999:          continue;
                   8000:        }
                   8001:        
1.241     brouard  8002:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  8003:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  8004:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  8005: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  8006:        k=3; /* Offset */
1.268     brouard  8007:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  8008:          if(i==1)
                   8009:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   8010:          else
                   8011:            fprintf(ficgp,", '' ");
                   8012:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  8013:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.324     brouard  8014:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   8015:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  8016:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  8017:          /* for (j=2; j<= nlstate ; j ++) */
                   8018:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   8019:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  8020:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  8021:        } /* nlstate */
1.264     brouard  8022:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  8023:       } /* end cpt state*/ 
                   8024:     } /* end covariate */  
1.296     brouard  8025:   } /* End if prevbcast */
1.218     brouard  8026:   
1.223     brouard  8027:   /* 8eme */
1.218     brouard  8028:   if(prevfcast==1){
1.288     brouard  8029:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  8030:     
1.237     brouard  8031:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   8032:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  8033:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  8034:        continue;
1.211     brouard  8035:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  8036:        strcpy(gplotlabel,"(");      
1.288     brouard  8037:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  8038:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8039:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8040:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8041:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8042:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8043:          vlv= nbcode[Tvaraff[k]][lv];
                   8044:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  8045:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  8046:        }
1.237     brouard  8047:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8048:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  8049:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  8050:        }       
1.264     brouard  8051:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  8052:        fprintf(ficgp,"\n#\n");
                   8053:        if(invalidvarcomb[k1]){
                   8054:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   8055:          continue;
                   8056:        }
                   8057:        
                   8058:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  8059:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  8060:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  8061:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  8062: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  8063: 
                   8064:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   8065:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8066:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8067:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  8068:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8069:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   8070:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8071:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  8072:          if(i==istart){
1.227     brouard  8073:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   8074:          }else{
                   8075:            fprintf(ficgp,",\\\n '' ");
                   8076:          }
                   8077:          if(cptcoveff ==0){ /* No covariate */
                   8078:            ioffset=2; /* Age is in 2 */
                   8079:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8080:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8081:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8082:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8083:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  8084:            if(i==nlstate+1){
1.270     brouard  8085:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  8086:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   8087:              fprintf(ficgp,",\\\n '' ");
                   8088:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  8089:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  8090:                     offyear,                           \
1.268     brouard  8091:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  8092:            }else
1.227     brouard  8093:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   8094:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   8095:          }else{ /* more than 2 covariates */
1.270     brouard  8096:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   8097:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8098:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   8099:            iyearc=ioffset-1;
                   8100:            iagec=ioffset;
1.227     brouard  8101:            fprintf(ficgp," u %d:(",ioffset); 
                   8102:            kl=0;
                   8103:            strcpy(gplotcondition,"(");
                   8104:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   8105:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   8106:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8107:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8108:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8109:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   8110:              kl++;
                   8111:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   8112:              kl++;
                   8113:              if(k <cptcoveff && cptcoveff>1)
                   8114:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   8115:            }
                   8116:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   8117:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   8118:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   8119:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   8120:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   8121:            if(i==nlstate+1){
1.270     brouard  8122:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   8123:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  8124:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  8125:              fprintf(ficgp," u %d:(",iagec); 
                   8126:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   8127:                      iyearc, iagec, offyear,                           \
                   8128:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  8129: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  8130:            }else{
                   8131:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   8132:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   8133:            }
                   8134:          } /* end if covariate */
                   8135:        } /* nlstate */
1.264     brouard  8136:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  8137:       } /* end cpt state*/
                   8138:     } /* end covariate */
                   8139:   } /* End if prevfcast */
1.227     brouard  8140:   
1.296     brouard  8141:   if(prevbcast==1){
1.268     brouard  8142:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   8143:     
                   8144:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   8145:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   8146:       if(m != 1 && TKresult[nres]!= k1)
                   8147:        continue;
                   8148:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   8149:        strcpy(gplotlabel,"(");      
                   8150:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   8151:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8152:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8153:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8154:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8155:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8156:          vlv= nbcode[Tvaraff[k]][lv];
                   8157:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   8158:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   8159:        }
                   8160:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8161:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8162:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8163:        }       
                   8164:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   8165:        fprintf(ficgp,"\n#\n");
                   8166:        if(invalidvarcomb[k1]){
                   8167:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   8168:          continue;
                   8169:        }
                   8170:        
                   8171:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   8172:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   8173:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   8174:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   8175: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   8176: 
                   8177:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   8178:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8179:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   8180:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   8181:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8182:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   8183:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8184:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   8185:          if(i==istart){
                   8186:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   8187:          }else{
                   8188:            fprintf(ficgp,",\\\n '' ");
                   8189:          }
                   8190:          if(cptcoveff ==0){ /* No covariate */
                   8191:            ioffset=2; /* Age is in 2 */
                   8192:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8193:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8194:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   8195:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   8196:            fprintf(ficgp," u %d:(", ioffset); 
                   8197:            if(i==nlstate+1){
1.270     brouard  8198:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  8199:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   8200:              fprintf(ficgp,",\\\n '' ");
                   8201:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  8202:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  8203:                     offbyear,                          \
                   8204:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   8205:            }else
                   8206:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   8207:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   8208:          }else{ /* more than 2 covariates */
1.270     brouard  8209:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   8210:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   8211:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   8212:            iyearc=ioffset-1;
                   8213:            iagec=ioffset;
1.268     brouard  8214:            fprintf(ficgp," u %d:(",ioffset); 
                   8215:            kl=0;
                   8216:            strcpy(gplotcondition,"(");
                   8217:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   8218:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   8219:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8220:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8221:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8222:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   8223:              kl++;
                   8224:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   8225:              kl++;
                   8226:              if(k <cptcoveff && cptcoveff>1)
                   8227:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   8228:            }
                   8229:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   8230:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   8231:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   8232:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   8233:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   8234:            if(i==nlstate+1){
1.270     brouard  8235:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   8236:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  8237:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  8238:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  8239:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  8240:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   8241:                      iyearc,iagec,offbyear,                            \
                   8242:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  8243: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   8244:            }else{
                   8245:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   8246:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   8247:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   8248:            }
                   8249:          } /* end if covariate */
                   8250:        } /* nlstate */
                   8251:        fprintf(ficgp,"\nset out; unset label;\n");
                   8252:       } /* end cpt state*/
                   8253:     } /* end covariate */
1.296     brouard  8254:   } /* End if prevbcast */
1.268     brouard  8255:   
1.227     brouard  8256:   
1.238     brouard  8257:   /* 9eme writing MLE parameters */
                   8258:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  8259:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  8260:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  8261:     for(k=1; k <=(nlstate+ndeath); k++){
                   8262:       if (k != i) {
1.227     brouard  8263:        fprintf(ficgp,"#   current state %d\n",k);
                   8264:        for(j=1; j <=ncovmodel; j++){
                   8265:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   8266:          jk++; 
                   8267:        }
                   8268:        fprintf(ficgp,"\n");
1.126     brouard  8269:       }
                   8270:     }
1.223     brouard  8271:   }
1.187     brouard  8272:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  8273:   
1.145     brouard  8274:   /*goto avoid;*/
1.238     brouard  8275:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   8276:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  8277:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   8278:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   8279:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   8280:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   8281:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8282:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8283:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8284:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8285:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   8286:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8287:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   8288:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   8289:   fprintf(ficgp,"#\n");
1.223     brouard  8290:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  8291:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  8292:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  8293:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  8294:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   8295:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  8296:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  8297:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  8298:        continue;
1.264     brouard  8299:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   8300:       strcpy(gplotlabel,"(");
1.276     brouard  8301:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  8302:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8303:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8304:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8305:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8306:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8307:        vlv= nbcode[Tvaraff[k]][lv];
                   8308:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   8309:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   8310:       }
1.237     brouard  8311:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8312:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  8313:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  8314:       }        
1.264     brouard  8315:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  8316:       fprintf(ficgp,"\n#\n");
1.264     brouard  8317:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  8318:       fprintf(ficgp,"\nset key outside ");
                   8319:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   8320:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  8321:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   8322:       if (ng==1){
                   8323:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   8324:        fprintf(ficgp,"\nunset log y");
                   8325:       }else if (ng==2){
                   8326:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   8327:        fprintf(ficgp,"\nset log y");
                   8328:       }else if (ng==3){
                   8329:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   8330:        fprintf(ficgp,"\nset log y");
                   8331:       }else
                   8332:        fprintf(ficgp,"\nunset title ");
                   8333:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   8334:       i=1;
                   8335:       for(k2=1; k2<=nlstate; k2++) {
                   8336:        k3=i;
                   8337:        for(k=1; k<=(nlstate+ndeath); k++) {
                   8338:          if (k != k2){
                   8339:            switch( ng) {
                   8340:            case 1:
                   8341:              if(nagesqr==0)
                   8342:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   8343:              else /* nagesqr =1 */
                   8344:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8345:              break;
                   8346:            case 2: /* ng=2 */
                   8347:              if(nagesqr==0)
                   8348:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   8349:              else /* nagesqr =1 */
                   8350:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8351:              break;
                   8352:            case 3:
                   8353:              if(nagesqr==0)
                   8354:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   8355:              else /* nagesqr =1 */
                   8356:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   8357:              break;
                   8358:            }
                   8359:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  8360:            ijp=1; /* product no age */
                   8361:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   8362:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  8363:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  8364:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.325   ! brouard  8365:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*//* Bug valgrind */
1.268     brouard  8366:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.325   ! brouard  8367:                    if(DummyV[j]==0){/* Bug valgrind */
1.268     brouard  8368:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   8369:                    }else{ /* quantitative */
                   8370:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   8371:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8372:                    }
                   8373:                    ij++;
1.237     brouard  8374:                  }
1.268     brouard  8375:                } 
                   8376:              }else if(cptcovprod >0){
                   8377:                if(j==Tprod[ijp]) { /* */ 
                   8378:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   8379:                  if(ijp <=cptcovprod) { /* Product */
                   8380:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   8381:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   8382:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   8383:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   8384:                      }else{ /* Vn is dummy and Vm is quanti */
                   8385:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   8386:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8387:                      }
                   8388:                    }else{ /* Vn*Vm Vn is quanti */
                   8389:                      if(DummyV[Tvard[ijp][2]]==0){
                   8390:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   8391:                      }else{ /* Both quanti */
                   8392:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8393:                      }
1.237     brouard  8394:                    }
1.268     brouard  8395:                    ijp++;
1.237     brouard  8396:                  }
1.268     brouard  8397:                } /* end Tprod */
1.237     brouard  8398:              } else{  /* simple covariate */
1.264     brouard  8399:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  8400:                if(Dummy[j]==0){
                   8401:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   8402:                }else{ /* quantitative */
                   8403:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  8404:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  8405:                }
1.237     brouard  8406:              } /* end simple */
                   8407:            } /* end j */
1.223     brouard  8408:          }else{
                   8409:            i=i-ncovmodel;
                   8410:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   8411:              fprintf(ficgp," (1.");
                   8412:          }
1.227     brouard  8413:          
1.223     brouard  8414:          if(ng != 1){
                   8415:            fprintf(ficgp,")/(1");
1.227     brouard  8416:            
1.264     brouard  8417:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8418:              if(nagesqr==0)
1.264     brouard  8419:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8420:              else /* nagesqr =1 */
1.264     brouard  8421:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8422:               
1.223     brouard  8423:              ij=1;
                   8424:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8425:                 if(cptcovage >0){ 
                   8426:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8427:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8428:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8429:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8430:                       ij++;
                   8431:                     }
                   8432:                   }
                   8433:                 }else
                   8434:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8435:              }
                   8436:              fprintf(ficgp,")");
                   8437:            }
                   8438:            fprintf(ficgp,")");
                   8439:            if(ng ==2)
1.276     brouard  8440:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8441:            else /* ng= 3 */
1.276     brouard  8442:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8443:          }else{ /* end ng <> 1 */
                   8444:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8445:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8446:          }
                   8447:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8448:            fprintf(ficgp,",");
                   8449:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8450:            fprintf(ficgp,",");
                   8451:          i=i+ncovmodel;
                   8452:        } /* end k */
                   8453:       } /* end k2 */
1.276     brouard  8454:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8455:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8456:     } /* end k1 */
1.223     brouard  8457:   } /* end ng */
                   8458:   /* avoid: */
                   8459:   fflush(ficgp); 
1.126     brouard  8460: }  /* end gnuplot */
                   8461: 
                   8462: 
                   8463: /*************** Moving average **************/
1.219     brouard  8464: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8465:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8466:    
1.222     brouard  8467:    int i, cpt, cptcod;
                   8468:    int modcovmax =1;
                   8469:    int mobilavrange, mob;
                   8470:    int iage=0;
1.288     brouard  8471:    int firstA1=0, firstA2=0;
1.222     brouard  8472: 
1.266     brouard  8473:    double sum=0., sumr=0.;
1.222     brouard  8474:    double age;
1.266     brouard  8475:    double *sumnewp, *sumnewm, *sumnewmr;
                   8476:    double *agemingood, *agemaxgood; 
                   8477:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8478:   
                   8479:   
1.278     brouard  8480:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8481:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8482: 
                   8483:    sumnewp = vector(1,ncovcombmax);
                   8484:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8485:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8486:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8487:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8488:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8489:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8490: 
                   8491:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8492:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8493:      sumnewp[cptcod]=0.;
1.266     brouard  8494:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8495:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8496:    }
                   8497:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8498:   
1.266     brouard  8499:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8500:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8501:      else mobilavrange=mobilav;
                   8502:      for (age=bage; age<=fage; age++)
                   8503:        for (i=1; i<=nlstate;i++)
                   8504:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8505:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8506:      /* We keep the original values on the extreme ages bage, fage and for 
                   8507:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8508:        we use a 5 terms etc. until the borders are no more concerned. 
                   8509:      */ 
                   8510:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8511:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8512:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8513:           sumnewm[cptcod]=0.;
                   8514:           for (i=1; i<=nlstate;i++){
1.222     brouard  8515:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8516:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8517:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8518:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8519:             }
                   8520:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8521:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8522:           } /* end i */
                   8523:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8524:         } /* end cptcod */
1.222     brouard  8525:        }/* end age */
                   8526:      }/* end mob */
1.266     brouard  8527:    }else{
                   8528:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8529:      return -1;
1.266     brouard  8530:    }
                   8531: 
                   8532:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8533:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8534:      if(invalidvarcomb[cptcod]){
                   8535:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8536:        continue;
                   8537:      }
1.219     brouard  8538: 
1.266     brouard  8539:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8540:        sumnewm[cptcod]=0.;
                   8541:        sumnewmr[cptcod]=0.;
                   8542:        for (i=1; i<=nlstate;i++){
                   8543:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8544:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8545:        }
                   8546:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8547:         agemingoodr[cptcod]=age;
                   8548:        }
                   8549:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8550:           agemingood[cptcod]=age;
                   8551:        }
                   8552:      } /* age */
                   8553:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8554:        sumnewm[cptcod]=0.;
1.266     brouard  8555:        sumnewmr[cptcod]=0.;
1.222     brouard  8556:        for (i=1; i<=nlstate;i++){
                   8557:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8558:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8559:        }
                   8560:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8561:         agemaxgoodr[cptcod]=age;
1.222     brouard  8562:        }
                   8563:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8564:         agemaxgood[cptcod]=age;
                   8565:        }
                   8566:      } /* age */
                   8567:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8568:      /* but they will change */
1.288     brouard  8569:      firstA1=0;firstA2=0;
1.266     brouard  8570:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8571:        sumnewm[cptcod]=0.;
                   8572:        sumnewmr[cptcod]=0.;
                   8573:        for (i=1; i<=nlstate;i++){
                   8574:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8575:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8576:        }
                   8577:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8578:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8579:           agemaxgoodr[cptcod]=age;  /* age min */
                   8580:           for (i=1; i<=nlstate;i++)
                   8581:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8582:         }else{ /* bad we change the value with the values of good ages */
                   8583:           for (i=1; i<=nlstate;i++){
                   8584:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8585:           } /* i */
                   8586:         } /* end bad */
                   8587:        }else{
                   8588:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8589:           agemaxgood[cptcod]=age;
                   8590:         }else{ /* bad we change the value with the values of good ages */
                   8591:           for (i=1; i<=nlstate;i++){
                   8592:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8593:           } /* i */
                   8594:         } /* end bad */
                   8595:        }/* end else */
                   8596:        sum=0.;sumr=0.;
                   8597:        for (i=1; i<=nlstate;i++){
                   8598:         sum+=mobaverage[(int)age][i][cptcod];
                   8599:         sumr+=probs[(int)age][i][cptcod];
                   8600:        }
                   8601:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8602:         if(!firstA1){
                   8603:           firstA1=1;
                   8604:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8605:         }
                   8606:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8607:        } /* end bad */
                   8608:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8609:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8610:         if(!firstA2){
                   8611:           firstA2=1;
                   8612:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8613:         }
                   8614:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8615:        } /* end bad */
                   8616:      }/* age */
1.266     brouard  8617: 
                   8618:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8619:        sumnewm[cptcod]=0.;
1.266     brouard  8620:        sumnewmr[cptcod]=0.;
1.222     brouard  8621:        for (i=1; i<=nlstate;i++){
                   8622:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8623:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8624:        } 
                   8625:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8626:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8627:           agemingoodr[cptcod]=age;
                   8628:           for (i=1; i<=nlstate;i++)
                   8629:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8630:         }else{ /* bad we change the value with the values of good ages */
                   8631:           for (i=1; i<=nlstate;i++){
                   8632:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8633:           } /* i */
                   8634:         } /* end bad */
                   8635:        }else{
                   8636:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8637:           agemingood[cptcod]=age;
                   8638:         }else{ /* bad */
                   8639:           for (i=1; i<=nlstate;i++){
                   8640:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8641:           } /* i */
                   8642:         } /* end bad */
                   8643:        }/* end else */
                   8644:        sum=0.;sumr=0.;
                   8645:        for (i=1; i<=nlstate;i++){
                   8646:         sum+=mobaverage[(int)age][i][cptcod];
                   8647:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8648:        }
1.266     brouard  8649:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8650:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8651:        } /* end bad */
                   8652:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8653:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8654:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8655:        } /* end bad */
                   8656:      }/* age */
1.266     brouard  8657: 
1.222     brouard  8658:                
                   8659:      for (age=bage; age<=fage; age++){
1.235     brouard  8660:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8661:        sumnewp[cptcod]=0.;
                   8662:        sumnewm[cptcod]=0.;
                   8663:        for (i=1; i<=nlstate;i++){
                   8664:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8665:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8666:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8667:        }
                   8668:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8669:      }
                   8670:      /* printf("\n"); */
                   8671:      /* } */
1.266     brouard  8672: 
1.222     brouard  8673:      /* brutal averaging */
1.266     brouard  8674:      /* for (i=1; i<=nlstate;i++){ */
                   8675:      /*   for (age=1; age<=bage; age++){ */
                   8676:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8677:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8678:      /*   }     */
                   8679:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8680:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8681:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8682:      /*   } */
                   8683:      /* } /\* end i status *\/ */
                   8684:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8685:      /*   for (age=1; age<=AGESUP; age++){ */
                   8686:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8687:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8688:      /*   } */
                   8689:      /* } */
1.222     brouard  8690:    }/* end cptcod */
1.266     brouard  8691:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8692:    free_vector(agemaxgood,1, ncovcombmax);
                   8693:    free_vector(agemingood,1, ncovcombmax);
                   8694:    free_vector(agemingoodr,1, ncovcombmax);
                   8695:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8696:    free_vector(sumnewm,1, ncovcombmax);
                   8697:    free_vector(sumnewp,1, ncovcombmax);
                   8698:    return 0;
                   8699:  }/* End movingaverage */
1.218     brouard  8700:  
1.126     brouard  8701: 
1.296     brouard  8702:  
1.126     brouard  8703: /************** Forecasting ******************/
1.296     brouard  8704: /* void prevforecast(char fileres[], double dateintmean, double anprojd, double mprojd, double jprojd, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anprojf, double p[], int cptcoveff)*/
                   8705: void prevforecast(char fileres[], double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8706:   /* dateintemean, mean date of interviews
                   8707:      dateprojd, year, month, day of starting projection 
                   8708:      dateprojf date of end of projection;year of end of projection (same day and month as proj1).
1.126     brouard  8709:      agemin, agemax range of age
                   8710:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8711:   */
1.296     brouard  8712:   /* double anprojd, mprojd, jprojd; */
                   8713:   /* double anprojf, mprojf, jprojf; */
1.267     brouard  8714:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8715:   double agec; /* generic age */
1.296     brouard  8716:   double agelim, ppij, yp,yp1,yp2;
1.126     brouard  8717:   double *popeffectif,*popcount;
                   8718:   double ***p3mat;
1.218     brouard  8719:   /* double ***mobaverage; */
1.126     brouard  8720:   char fileresf[FILENAMELENGTH];
                   8721: 
                   8722:   agelim=AGESUP;
1.211     brouard  8723:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8724:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8725:      We still use firstpass and lastpass as another selection.
                   8726:   */
1.214     brouard  8727:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8728:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8729:  
1.201     brouard  8730:   strcpy(fileresf,"F_"); 
                   8731:   strcat(fileresf,fileresu);
1.126     brouard  8732:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8733:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8734:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8735:   }
1.235     brouard  8736:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8737:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8738: 
1.225     brouard  8739:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8740: 
                   8741: 
                   8742:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8743:   if (stepm<=12) stepsize=1;
                   8744:   if(estepm < stepm){
                   8745:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8746:   }
1.270     brouard  8747:   else{
                   8748:     hstepm=estepm;   
                   8749:   }
                   8750:   if(estepm > stepm){ /* Yes every two year */
                   8751:     stepsize=2;
                   8752:   }
1.296     brouard  8753:   hstepm=hstepm/stepm;
1.126     brouard  8754: 
1.296     brouard  8755:   
                   8756:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8757:   /*                              fractional in yp1 *\/ */
                   8758:   /* aintmean=yp; */
                   8759:   /* yp2=modf((yp1*12),&yp); */
                   8760:   /* mintmean=yp; */
                   8761:   /* yp1=modf((yp2*30.5),&yp); */
                   8762:   /* jintmean=yp; */
                   8763:   /* if(jintmean==0) jintmean=1; */
                   8764:   /* if(mintmean==0) mintmean=1; */
1.126     brouard  8765: 
1.296     brouard  8766: 
                   8767:   /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */
                   8768:   /* date2dmy(dateprojd,&jprojd, &mprojd, &anprojd); */
                   8769:   /* date2dmy(dateprojf,&jprojf, &mprojf, &anprojf); */
1.227     brouard  8770:   i1=pow(2,cptcoveff);
1.126     brouard  8771:   if (cptcovn < 1){i1=1;}
                   8772:   
1.296     brouard  8773:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2); 
1.126     brouard  8774:   
                   8775:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8776:   
1.126     brouard  8777: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8778:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8779:   for(k=1; k<=i1;k++){
1.253     brouard  8780:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8781:       continue;
1.227     brouard  8782:     if(invalidvarcomb[k]){
                   8783:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8784:       continue;
                   8785:     }
                   8786:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8787:     for(j=1;j<=cptcoveff;j++) {
                   8788:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8789:     }
1.235     brouard  8790:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8791:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8792:     }
1.227     brouard  8793:     fprintf(ficresf," yearproj age");
                   8794:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8795:       for(i=1; i<=nlstate;i++)               
                   8796:        fprintf(ficresf," p%d%d",i,j);
                   8797:       fprintf(ficresf," wp.%d",j);
                   8798:     }
1.296     brouard  8799:     for (yearp=0; yearp<=(anprojf-anprojd);yearp +=stepsize) {
1.227     brouard  8800:       fprintf(ficresf,"\n");
1.296     brouard  8801:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jprojd,mprojd,anprojd+yearp);   
1.270     brouard  8802:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8803:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8804:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8805:        nhstepm = nhstepm/hstepm; 
                   8806:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8807:        oldm=oldms;savm=savms;
1.268     brouard  8808:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8809:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8810:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8811:        for (h=0; h<=nhstepm; h++){
                   8812:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8813:            break;
                   8814:          }
                   8815:        }
                   8816:        fprintf(ficresf,"\n");
                   8817:        for(j=1;j<=cptcoveff;j++) 
                   8818:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8819:        fprintf(ficresf,"%.f %.f ",anprojd+yearp,agec+h*hstepm/YEARM*stepm);
1.268     brouard  8820:        
                   8821:        for(j=1; j<=nlstate+ndeath;j++) {
                   8822:          ppij=0.;
                   8823:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8824:            if (mobilav>=1)
                   8825:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8826:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8827:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8828:            }
1.268     brouard  8829:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8830:          } /* end i */
                   8831:          fprintf(ficresf," %.3f", ppij);
                   8832:        }/* end j */
1.227     brouard  8833:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8834:       } /* end agec */
1.266     brouard  8835:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8836:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8837:     } /* end yearp */
                   8838:   } /* end  k */
1.219     brouard  8839:        
1.126     brouard  8840:   fclose(ficresf);
1.215     brouard  8841:   printf("End of Computing forecasting \n");
                   8842:   fprintf(ficlog,"End of Computing forecasting\n");
                   8843: 
1.126     brouard  8844: }
                   8845: 
1.269     brouard  8846: /************** Back Forecasting ******************/
1.296     brouard  8847:  /* void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
                   8848:  void prevbackforecast(char fileres[], double ***prevacurrent, double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8849:   /* back1, year, month, day of starting backprojection
1.267     brouard  8850:      agemin, agemax range of age
                   8851:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8852:      anback2 year of end of backprojection (same day and month as back1).
                   8853:      prevacurrent and prev are prevalences.
1.267     brouard  8854:   */
                   8855:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8856:   double agec; /* generic age */
1.302     brouard  8857:   double agelim, ppij, ppi, yp,yp1,yp2; /* ,jintmean,mintmean,aintmean;*/
1.267     brouard  8858:   double *popeffectif,*popcount;
                   8859:   double ***p3mat;
                   8860:   /* double ***mobaverage; */
                   8861:   char fileresfb[FILENAMELENGTH];
                   8862:  
1.268     brouard  8863:   agelim=AGEINF;
1.267     brouard  8864:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8865:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8866:      We still use firstpass and lastpass as another selection.
                   8867:   */
                   8868:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8869:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8870: 
                   8871:   /*Do we need to compute prevalence again?*/
                   8872: 
                   8873:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8874:   
                   8875:   strcpy(fileresfb,"FB_");
                   8876:   strcat(fileresfb,fileresu);
                   8877:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8878:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8879:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8880:   }
                   8881:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8882:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8883:   
                   8884:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8885:   
                   8886:    
                   8887:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8888:   if (stepm<=12) stepsize=1;
                   8889:   if(estepm < stepm){
                   8890:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8891:   }
1.270     brouard  8892:   else{
                   8893:     hstepm=estepm;   
                   8894:   }
                   8895:   if(estepm >= stepm){ /* Yes every two year */
                   8896:     stepsize=2;
                   8897:   }
1.267     brouard  8898:   
                   8899:   hstepm=hstepm/stepm;
1.296     brouard  8900:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8901:   /*                              fractional in yp1 *\/ */
                   8902:   /* aintmean=yp; */
                   8903:   /* yp2=modf((yp1*12),&yp); */
                   8904:   /* mintmean=yp; */
                   8905:   /* yp1=modf((yp2*30.5),&yp); */
                   8906:   /* jintmean=yp; */
                   8907:   /* if(jintmean==0) jintmean=1; */
                   8908:   /* if(mintmean==0) jintmean=1; */
1.267     brouard  8909:   
                   8910:   i1=pow(2,cptcoveff);
                   8911:   if (cptcovn < 1){i1=1;}
                   8912:   
1.296     brouard  8913:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
                   8914:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8915:   
                   8916:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8917:   
                   8918:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8919:   for(k=1; k<=i1;k++){
                   8920:     if(i1 != 1 && TKresult[nres]!= k)
                   8921:       continue;
                   8922:     if(invalidvarcomb[k]){
                   8923:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8924:       continue;
                   8925:     }
1.268     brouard  8926:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8927:     for(j=1;j<=cptcoveff;j++) {
                   8928:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8929:     }
                   8930:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8931:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8932:     }
                   8933:     fprintf(ficresfb," yearbproj age");
                   8934:     for(j=1; j<=nlstate+ndeath;j++){
                   8935:       for(i=1; i<=nlstate;i++)
1.268     brouard  8936:        fprintf(ficresfb," b%d%d",i,j);
                   8937:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8938:     }
1.296     brouard  8939:     for (yearp=0; yearp>=(anbackf-anbackd);yearp -=stepsize) {
1.267     brouard  8940:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8941:       fprintf(ficresfb,"\n");
1.296     brouard  8942:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jbackd,mbackd,anbackd+yearp);
1.273     brouard  8943:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8944:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8945:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8946:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8947:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8948:        nhstepm = nhstepm/hstepm;
                   8949:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8950:        oldm=oldms;savm=savms;
1.268     brouard  8951:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8952:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8953:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8954:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8955:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8956:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8957:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8958:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8959:            break;
                   8960:          }
                   8961:        }
                   8962:        fprintf(ficresfb,"\n");
                   8963:        for(j=1;j<=cptcoveff;j++)
                   8964:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8965:        fprintf(ficresfb,"%.f %.f ",anbackd+yearp,agec-h*hstepm/YEARM*stepm);
1.268     brouard  8966:        for(i=1; i<=nlstate+ndeath;i++) {
                   8967:          ppij=0.;ppi=0.;
                   8968:          for(j=1; j<=nlstate;j++) {
                   8969:            /* if (mobilav==1) */
1.269     brouard  8970:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8971:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8972:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8973:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8974:              /* else { */
                   8975:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8976:              /* } */
1.268     brouard  8977:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8978:          } /* end j */
                   8979:          if(ppi <0.99){
                   8980:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8981:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8982:          }
                   8983:          fprintf(ficresfb," %.3f", ppij);
                   8984:        }/* end j */
1.267     brouard  8985:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8986:       } /* end agec */
                   8987:     } /* end yearp */
                   8988:   } /* end k */
1.217     brouard  8989:   
1.267     brouard  8990:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8991:   
1.267     brouard  8992:   fclose(ficresfb);
                   8993:   printf("End of Computing Back forecasting \n");
                   8994:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8995:        
1.267     brouard  8996: }
1.217     brouard  8997: 
1.269     brouard  8998: /* Variance of prevalence limit: varprlim */
                   8999:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  9000:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  9001:  
                   9002:    char fileresvpl[FILENAMELENGTH];  
                   9003:    FILE *ficresvpl;
                   9004:    double **oldm, **savm;
                   9005:    double **varpl; /* Variances of prevalence limits by age */   
                   9006:    int i1, k, nres, j ;
                   9007:    
                   9008:     strcpy(fileresvpl,"VPL_");
                   9009:     strcat(fileresvpl,fileresu);
                   9010:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  9011:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  9012:       exit(0);
                   9013:     }
1.288     brouard  9014:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   9015:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  9016:     
                   9017:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   9018:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   9019:     
                   9020:     i1=pow(2,cptcoveff);
                   9021:     if (cptcovn < 1){i1=1;}
                   9022: 
                   9023:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9024:     for(k=1; k<=i1;k++){
                   9025:       if(i1 != 1 && TKresult[nres]!= k)
                   9026:        continue;
                   9027:       fprintf(ficresvpl,"\n#****** ");
                   9028:       printf("\n#****** ");
                   9029:       fprintf(ficlog,"\n#****** ");
                   9030:       for(j=1;j<=cptcoveff;j++) {
                   9031:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9032:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9033:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9034:       }
                   9035:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9036:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9037:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9038:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9039:       }        
                   9040:       fprintf(ficresvpl,"******\n");
                   9041:       printf("******\n");
                   9042:       fprintf(ficlog,"******\n");
                   9043:       
                   9044:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   9045:       oldm=oldms;savm=savms;
                   9046:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   9047:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   9048:       /*}*/
                   9049:     }
                   9050:     
                   9051:     fclose(ficresvpl);
1.288     brouard  9052:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   9053:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  9054: 
                   9055:  }
                   9056: /* Variance of back prevalence: varbprlim */
                   9057:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   9058:       /*------- Variance of back (stable) prevalence------*/
                   9059: 
                   9060:    char fileresvbl[FILENAMELENGTH];  
                   9061:    FILE  *ficresvbl;
                   9062: 
                   9063:    double **oldm, **savm;
                   9064:    double **varbpl; /* Variances of back prevalence limits by age */   
                   9065:    int i1, k, nres, j ;
                   9066: 
                   9067:    strcpy(fileresvbl,"VBL_");
                   9068:    strcat(fileresvbl,fileresu);
                   9069:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   9070:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   9071:      exit(0);
                   9072:    }
                   9073:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   9074:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   9075:    
                   9076:    
                   9077:    i1=pow(2,cptcoveff);
                   9078:    if (cptcovn < 1){i1=1;}
                   9079:    
                   9080:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9081:      for(k=1; k<=i1;k++){
                   9082:        if(i1 != 1 && TKresult[nres]!= k)
                   9083:         continue;
                   9084:        fprintf(ficresvbl,"\n#****** ");
                   9085:        printf("\n#****** ");
                   9086:        fprintf(ficlog,"\n#****** ");
                   9087:        for(j=1;j<=cptcoveff;j++) {
                   9088:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9089:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9090:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9091:        }
                   9092:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9093:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9094:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9095:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9096:        }
                   9097:        fprintf(ficresvbl,"******\n");
                   9098:        printf("******\n");
                   9099:        fprintf(ficlog,"******\n");
                   9100:        
                   9101:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   9102:        oldm=oldms;savm=savms;
                   9103:        
                   9104:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   9105:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   9106:        /*}*/
                   9107:      }
                   9108:    
                   9109:    fclose(ficresvbl);
                   9110:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   9111:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   9112: 
                   9113:  } /* End of varbprlim */
                   9114: 
1.126     brouard  9115: /************** Forecasting *****not tested NB*************/
1.227     brouard  9116: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  9117:   
1.227     brouard  9118: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   9119: /*   int *popage; */
                   9120: /*   double calagedatem, agelim, kk1, kk2; */
                   9121: /*   double *popeffectif,*popcount; */
                   9122: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   9123: /*   /\* double ***mobaverage; *\/ */
                   9124: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  9125: 
1.227     brouard  9126: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9127: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9128: /*   agelim=AGESUP; */
                   9129: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  9130:   
1.227     brouard  9131: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  9132:   
                   9133:   
1.227     brouard  9134: /*   strcpy(filerespop,"POP_");  */
                   9135: /*   strcat(filerespop,fileresu); */
                   9136: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   9137: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   9138: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   9139: /*   } */
                   9140: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   9141: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  9142: 
1.227     brouard  9143: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  9144: 
1.227     brouard  9145: /*   /\* if (mobilav!=0) { *\/ */
                   9146: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   9147: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   9148: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   9149: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   9150: /*   /\*   } *\/ */
                   9151: /*   /\* } *\/ */
1.126     brouard  9152: 
1.227     brouard  9153: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   9154: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  9155:   
1.227     brouard  9156: /*   agelim=AGESUP; */
1.126     brouard  9157:   
1.227     brouard  9158: /*   hstepm=1; */
                   9159: /*   hstepm=hstepm/stepm;  */
1.218     brouard  9160:        
1.227     brouard  9161: /*   if (popforecast==1) { */
                   9162: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   9163: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   9164: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   9165: /*     }  */
                   9166: /*     popage=ivector(0,AGESUP); */
                   9167: /*     popeffectif=vector(0,AGESUP); */
                   9168: /*     popcount=vector(0,AGESUP); */
1.126     brouard  9169:     
1.227     brouard  9170: /*     i=1;    */
                   9171: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  9172:     
1.227     brouard  9173: /*     imx=i; */
                   9174: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   9175: /*   } */
1.218     brouard  9176:   
1.227     brouard  9177: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   9178: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   9179: /*       k=k+1; */
                   9180: /*       fprintf(ficrespop,"\n#******"); */
                   9181: /*       for(j=1;j<=cptcoveff;j++) { */
                   9182: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   9183: /*       } */
                   9184: /*       fprintf(ficrespop,"******\n"); */
                   9185: /*       fprintf(ficrespop,"# Age"); */
                   9186: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   9187: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  9188:       
1.227     brouard  9189: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   9190: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  9191:        
1.227     brouard  9192: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   9193: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   9194: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  9195:          
1.227     brouard  9196: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9197: /*       oldm=oldms;savm=savms; */
                   9198: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  9199:          
1.227     brouard  9200: /*       for (h=0; h<=nhstepm; h++){ */
                   9201: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   9202: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   9203: /*         }  */
                   9204: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   9205: /*           kk1=0.;kk2=0; */
                   9206: /*           for(i=1; i<=nlstate;i++) {               */
                   9207: /*             if (mobilav==1)  */
                   9208: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   9209: /*             else { */
                   9210: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   9211: /*             } */
                   9212: /*           } */
                   9213: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   9214: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   9215: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   9216: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   9217: /*           } */
                   9218: /*         } */
                   9219: /*         for(i=1; i<=nlstate;i++){ */
                   9220: /*           kk1=0.; */
                   9221: /*           for(j=1; j<=nlstate;j++){ */
                   9222: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   9223: /*           } */
                   9224: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   9225: /*         } */
1.218     brouard  9226:            
1.227     brouard  9227: /*         if (h==(int)(calagedatem+12*cpt)) */
                   9228: /*           for(j=1; j<=nlstate;j++)  */
                   9229: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   9230: /*       } */
                   9231: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9232: /*     } */
                   9233: /*       } */
1.218     brouard  9234:       
1.227     brouard  9235: /*       /\******\/ */
1.218     brouard  9236:       
1.227     brouard  9237: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   9238: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   9239: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   9240: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   9241: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  9242:          
1.227     brouard  9243: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9244: /*       oldm=oldms;savm=savms; */
                   9245: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9246: /*       for (h=0; h<=nhstepm; h++){ */
                   9247: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   9248: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   9249: /*         }  */
                   9250: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   9251: /*           kk1=0.;kk2=0; */
                   9252: /*           for(i=1; i<=nlstate;i++) {               */
                   9253: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   9254: /*           } */
                   9255: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   9256: /*         } */
                   9257: /*       } */
                   9258: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   9259: /*     } */
                   9260: /*       } */
                   9261: /*     }  */
                   9262: /*   } */
1.218     brouard  9263:   
1.227     brouard  9264: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  9265:   
1.227     brouard  9266: /*   if (popforecast==1) { */
                   9267: /*     free_ivector(popage,0,AGESUP); */
                   9268: /*     free_vector(popeffectif,0,AGESUP); */
                   9269: /*     free_vector(popcount,0,AGESUP); */
                   9270: /*   } */
                   9271: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9272: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9273: /*   fclose(ficrespop); */
                   9274: /* } /\* End of popforecast *\/ */
1.218     brouard  9275:  
1.126     brouard  9276: int fileappend(FILE *fichier, char *optionfich)
                   9277: {
                   9278:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   9279:     printf("Problem with file: %s\n", optionfich);
                   9280:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   9281:     return (0);
                   9282:   }
                   9283:   fflush(fichier);
                   9284:   return (1);
                   9285: }
                   9286: 
                   9287: 
                   9288: /**************** function prwizard **********************/
                   9289: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   9290: {
                   9291: 
                   9292:   /* Wizard to print covariance matrix template */
                   9293: 
1.164     brouard  9294:   char ca[32], cb[32];
                   9295:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  9296:   int numlinepar;
                   9297: 
                   9298:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9299:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9300:   for(i=1; i <=nlstate; i++){
                   9301:     jj=0;
                   9302:     for(j=1; j <=nlstate+ndeath; j++){
                   9303:       if(j==i) continue;
                   9304:       jj++;
                   9305:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   9306:       printf("%1d%1d",i,j);
                   9307:       fprintf(ficparo,"%1d%1d",i,j);
                   9308:       for(k=1; k<=ncovmodel;k++){
                   9309:        /*        printf(" %lf",param[i][j][k]); */
                   9310:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   9311:        printf(" 0.");
                   9312:        fprintf(ficparo," 0.");
                   9313:       }
                   9314:       printf("\n");
                   9315:       fprintf(ficparo,"\n");
                   9316:     }
                   9317:   }
                   9318:   printf("# Scales (for hessian or gradient estimation)\n");
                   9319:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   9320:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   9321:   for(i=1; i <=nlstate; i++){
                   9322:     jj=0;
                   9323:     for(j=1; j <=nlstate+ndeath; j++){
                   9324:       if(j==i) continue;
                   9325:       jj++;
                   9326:       fprintf(ficparo,"%1d%1d",i,j);
                   9327:       printf("%1d%1d",i,j);
                   9328:       fflush(stdout);
                   9329:       for(k=1; k<=ncovmodel;k++){
                   9330:        /*      printf(" %le",delti3[i][j][k]); */
                   9331:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   9332:        printf(" 0.");
                   9333:        fprintf(ficparo," 0.");
                   9334:       }
                   9335:       numlinepar++;
                   9336:       printf("\n");
                   9337:       fprintf(ficparo,"\n");
                   9338:     }
                   9339:   }
                   9340:   printf("# Covariance matrix\n");
                   9341: /* # 121 Var(a12)\n\ */
                   9342: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9343: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   9344: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   9345: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   9346: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   9347: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   9348: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   9349:   fflush(stdout);
                   9350:   fprintf(ficparo,"# Covariance matrix\n");
                   9351:   /* # 121 Var(a12)\n\ */
                   9352:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9353:   /* #   ...\n\ */
                   9354:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   9355:   
                   9356:   for(itimes=1;itimes<=2;itimes++){
                   9357:     jj=0;
                   9358:     for(i=1; i <=nlstate; i++){
                   9359:       for(j=1; j <=nlstate+ndeath; j++){
                   9360:        if(j==i) continue;
                   9361:        for(k=1; k<=ncovmodel;k++){
                   9362:          jj++;
                   9363:          ca[0]= k+'a'-1;ca[1]='\0';
                   9364:          if(itimes==1){
                   9365:            printf("#%1d%1d%d",i,j,k);
                   9366:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   9367:          }else{
                   9368:            printf("%1d%1d%d",i,j,k);
                   9369:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   9370:            /*  printf(" %.5le",matcov[i][j]); */
                   9371:          }
                   9372:          ll=0;
                   9373:          for(li=1;li <=nlstate; li++){
                   9374:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   9375:              if(lj==li) continue;
                   9376:              for(lk=1;lk<=ncovmodel;lk++){
                   9377:                ll++;
                   9378:                if(ll<=jj){
                   9379:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   9380:                  if(ll<jj){
                   9381:                    if(itimes==1){
                   9382:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9383:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9384:                    }else{
                   9385:                      printf(" 0.");
                   9386:                      fprintf(ficparo," 0.");
                   9387:                    }
                   9388:                  }else{
                   9389:                    if(itimes==1){
                   9390:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   9391:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   9392:                    }else{
                   9393:                      printf(" 0.");
                   9394:                      fprintf(ficparo," 0.");
                   9395:                    }
                   9396:                  }
                   9397:                }
                   9398:              } /* end lk */
                   9399:            } /* end lj */
                   9400:          } /* end li */
                   9401:          printf("\n");
                   9402:          fprintf(ficparo,"\n");
                   9403:          numlinepar++;
                   9404:        } /* end k*/
                   9405:       } /*end j */
                   9406:     } /* end i */
                   9407:   } /* end itimes */
                   9408: 
                   9409: } /* end of prwizard */
                   9410: /******************* Gompertz Likelihood ******************************/
                   9411: double gompertz(double x[])
                   9412: { 
1.302     brouard  9413:   double A=0.0,B=0.,L=0.0,sump=0.,num=0.;
1.126     brouard  9414:   int i,n=0; /* n is the size of the sample */
                   9415: 
1.220     brouard  9416:   for (i=1;i<=imx ; i++) {
1.126     brouard  9417:     sump=sump+weight[i];
                   9418:     /*    sump=sump+1;*/
                   9419:     num=num+1;
                   9420:   }
1.302     brouard  9421:   L=0.0;
                   9422:   /* agegomp=AGEGOMP; */
1.126     brouard  9423:   /* for (i=0; i<=imx; i++) 
                   9424:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9425: 
1.302     brouard  9426:   for (i=1;i<=imx ; i++) {
                   9427:     /* mu(a)=mu(agecomp)*exp(teta*(age-agegomp))
                   9428:        mu(a)=x[1]*exp(x[2]*(age-agegomp)); x[1] and x[2] are per year.
                   9429:      * L= Product mu(agedeces)exp(-\int_ageexam^agedc mu(u) du ) for a death between agedc (in month) 
                   9430:      *   and agedc +1 month, cens[i]=0: log(x[1]/YEARM)
                   9431:      * +
                   9432:      * exp(-\int_ageexam^agecens mu(u) du ) when censored, cens[i]=1
                   9433:      */
                   9434:      if (wav[i] > 1 || agedc[i] < AGESUP) {
                   9435:        if (cens[i] == 1){
                   9436:         A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   9437:        } else if (cens[i] == 0){
1.126     brouard  9438:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
1.302     brouard  9439:          +log(x[1]/YEARM) +x[2]*(agedc[i]-agegomp)+log(YEARM);
                   9440:       } else
                   9441:         printf("Gompertz cens[%d] neither 1 nor 0\n",i);
1.126     brouard  9442:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
1.302     brouard  9443:        L=L+A*weight[i];
1.126     brouard  9444:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
1.302     brouard  9445:      }
                   9446:   }
1.126     brouard  9447: 
1.302     brouard  9448:   /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
1.126     brouard  9449:  
                   9450:   return -2*L*num/sump;
                   9451: }
                   9452: 
1.136     brouard  9453: #ifdef GSL
                   9454: /******************* Gompertz_f Likelihood ******************************/
                   9455: double gompertz_f(const gsl_vector *v, void *params)
                   9456: { 
1.302     brouard  9457:   double A=0.,B=0.,LL=0.0,sump=0.,num=0.;
1.136     brouard  9458:   double *x= (double *) v->data;
                   9459:   int i,n=0; /* n is the size of the sample */
                   9460: 
                   9461:   for (i=0;i<=imx-1 ; i++) {
                   9462:     sump=sump+weight[i];
                   9463:     /*    sump=sump+1;*/
                   9464:     num=num+1;
                   9465:   }
                   9466:  
                   9467:  
                   9468:   /* for (i=0; i<=imx; i++) 
                   9469:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9470:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9471:   for (i=1;i<=imx ; i++)
                   9472:     {
                   9473:       if (cens[i] == 1 && wav[i]>1)
                   9474:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9475:       
                   9476:       if (cens[i] == 0 && wav[i]>1)
                   9477:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9478:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9479:       
                   9480:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9481:       if (wav[i] > 1 ) { /* ??? */
                   9482:        LL=LL+A*weight[i];
                   9483:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9484:       }
                   9485:     }
                   9486: 
                   9487:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9488:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9489:  
                   9490:   return -2*LL*num/sump;
                   9491: }
                   9492: #endif
                   9493: 
1.126     brouard  9494: /******************* Printing html file ***********/
1.201     brouard  9495: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9496:                  int lastpass, int stepm, int weightopt, char model[],\
                   9497:                  int imx,  double p[],double **matcov,double agemortsup){
                   9498:   int i,k;
                   9499: 
                   9500:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9501:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9502:   for (i=1;i<=2;i++) 
                   9503:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9504:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9505:   fprintf(fichtm,"</ul>");
                   9506: 
                   9507: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9508: 
                   9509:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9510: 
                   9511:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9512:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9513: 
                   9514:  
                   9515:   fflush(fichtm);
                   9516: }
                   9517: 
                   9518: /******************* Gnuplot file **************/
1.201     brouard  9519: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9520: 
                   9521:   char dirfileres[132],optfileres[132];
1.164     brouard  9522: 
1.126     brouard  9523:   int ng;
                   9524: 
                   9525: 
                   9526:   /*#ifdef windows */
                   9527:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9528:     /*#endif */
                   9529: 
                   9530: 
                   9531:   strcpy(dirfileres,optionfilefiname);
                   9532:   strcpy(optfileres,"vpl");
1.199     brouard  9533:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9534:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9535:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9536:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9537:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9538: 
                   9539: } 
                   9540: 
1.136     brouard  9541: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9542: {
1.126     brouard  9543: 
1.136     brouard  9544:   /*-------- data file ----------*/
                   9545:   FILE *fic;
                   9546:   char dummy[]="                         ";
1.240     brouard  9547:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9548:   int lstra;
1.136     brouard  9549:   int linei, month, year,iout;
1.302     brouard  9550:   int noffset=0; /* This is the offset if BOM data file */
1.136     brouard  9551:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9552:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9553:   char *stratrunc;
1.223     brouard  9554: 
1.240     brouard  9555:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9556:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9557: 
1.240     brouard  9558:   for(v=1; v <=ncovcol;v++){
                   9559:     DummyV[v]=0;
                   9560:     FixedV[v]=0;
                   9561:   }
                   9562:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9563:     DummyV[v]=1;
                   9564:     FixedV[v]=0;
                   9565:   }
                   9566:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9567:     DummyV[v]=0;
                   9568:     FixedV[v]=1;
                   9569:   }
                   9570:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9571:     DummyV[v]=1;
                   9572:     FixedV[v]=1;
                   9573:   }
                   9574:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9575:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9576:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9577:   }
1.126     brouard  9578: 
1.136     brouard  9579:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9580:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9581:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9582:   }
1.126     brouard  9583: 
1.302     brouard  9584:     /* Is it a BOM UTF-8 Windows file? */
                   9585:   /* First data line */
                   9586:   linei=0;
                   9587:   while(fgets(line, MAXLINE, fic)) {
                   9588:     noffset=0;
                   9589:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   9590:     {
                   9591:       noffset=noffset+3;
                   9592:       printf("# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);fflush(stdout);
                   9593:       fprintf(ficlog,"# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);
                   9594:       fflush(ficlog); return 1;
                   9595:     }
                   9596:     /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   9597:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
                   9598:     {
                   9599:       noffset=noffset+2;
1.304     brouard  9600:       printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9601:       fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9602:       fflush(ficlog); return 1;
                   9603:     }
                   9604:     else if( line[0] == 0 && line[1] == 0)
                   9605:     {
                   9606:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   9607:        noffset=noffset+4;
1.304     brouard  9608:        printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9609:        fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9610:        fflush(ficlog); return 1;
                   9611:       }
                   9612:     } else{
                   9613:       ;/*printf(" Not a BOM file\n");*/
                   9614:     }
                   9615:         /* If line starts with a # it is a comment */
                   9616:     if (line[noffset] == '#') {
                   9617:       linei=linei+1;
                   9618:       break;
                   9619:     }else{
                   9620:       break;
                   9621:     }
                   9622:   }
                   9623:   fclose(fic);
                   9624:   if((fic=fopen(datafile,"r"))==NULL)    {
                   9625:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9626:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
                   9627:   }
                   9628:   /* Not a Bom file */
                   9629:   
1.136     brouard  9630:   i=1;
                   9631:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9632:     linei=linei+1;
                   9633:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9634:       if(line[j] == '\t')
                   9635:        line[j] = ' ';
                   9636:     }
                   9637:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9638:       ;
                   9639:     };
                   9640:     line[j+1]=0;  /* Trims blanks at end of line */
                   9641:     if(line[0]=='#'){
                   9642:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9643:       printf("Comment line\n%s\n",line);
                   9644:       continue;
                   9645:     }
                   9646:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9647:     strcpy(line, linetmp);
1.223     brouard  9648:     
                   9649:     /* Loops on waves */
                   9650:     for (j=maxwav;j>=1;j--){
                   9651:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9652:        cutv(stra, strb, line, ' '); 
                   9653:        if(strb[0]=='.') { /* Missing value */
                   9654:          lval=-1;
                   9655:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9656:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9657:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9658:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9659:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9660:            return 1;
                   9661:          }
                   9662:        }else{
                   9663:          errno=0;
                   9664:          /* what_kind_of_number(strb); */
                   9665:          dval=strtod(strb,&endptr); 
                   9666:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9667:          /* if(strb != endptr && *endptr == '\0') */
                   9668:          /*    dval=dlval; */
                   9669:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9670:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9671:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9672:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9673:            return 1;
                   9674:          }
                   9675:          cotqvar[j][iv][i]=dval; 
                   9676:          cotvar[j][ntv+iv][i]=dval; 
                   9677:        }
                   9678:        strcpy(line,stra);
1.223     brouard  9679:       }/* end loop ntqv */
1.225     brouard  9680:       
1.223     brouard  9681:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9682:        cutv(stra, strb, line, ' '); 
                   9683:        if(strb[0]=='.') { /* Missing value */
                   9684:          lval=-1;
                   9685:        }else{
                   9686:          errno=0;
                   9687:          lval=strtol(strb,&endptr,10); 
                   9688:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9689:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9690:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9691:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9692:            return 1;
                   9693:          }
                   9694:        }
                   9695:        if(lval <-1 || lval >1){
                   9696:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.319     brouard  9697:  Should be a value of %d(nth) covariate of wave %d (0 should be the value for the reference and 1\n \
1.223     brouard  9698:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9699:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9700:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9701:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9702:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9703:  output of IMaCh is often meaningless.\n                               \
1.319     brouard  9704:  Exiting.\n",lval,linei, i,line,iv,j);
1.238     brouard  9705:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.319     brouard  9706:  Should be a value of %d(nth) covariate of wave %d (0 should be the value for the reference and 1\n \
1.223     brouard  9707:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9708:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9709:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9710:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9711:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9712:  output of IMaCh is often meaningless.\n                               \
1.319     brouard  9713:  Exiting.\n",lval,linei, i,line,iv,j);fflush(ficlog);
1.238     brouard  9714:          return 1;
                   9715:        }
                   9716:        cotvar[j][iv][i]=(double)(lval);
                   9717:        strcpy(line,stra);
1.223     brouard  9718:       }/* end loop ntv */
1.225     brouard  9719:       
1.223     brouard  9720:       /* Statuses  at wave */
1.137     brouard  9721:       cutv(stra, strb, line, ' '); 
1.223     brouard  9722:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9723:        lval=-1;
1.136     brouard  9724:       }else{
1.238     brouard  9725:        errno=0;
                   9726:        lval=strtol(strb,&endptr,10); 
                   9727:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9728:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9729:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9730:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9731:          return 1;
                   9732:        }
1.136     brouard  9733:       }
1.225     brouard  9734:       
1.136     brouard  9735:       s[j][i]=lval;
1.225     brouard  9736:       
1.223     brouard  9737:       /* Date of Interview */
1.136     brouard  9738:       strcpy(line,stra);
                   9739:       cutv(stra, strb,line,' ');
1.169     brouard  9740:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9741:       }
1.169     brouard  9742:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9743:        month=99;
                   9744:        year=9999;
1.136     brouard  9745:       }else{
1.225     brouard  9746:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9747:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9748:        return 1;
1.136     brouard  9749:       }
                   9750:       anint[j][i]= (double) year; 
1.302     brouard  9751:       mint[j][i]= (double)month;
                   9752:       /* if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){ */
                   9753:       /*       printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9754:       /*       fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9755:       /* } */
1.136     brouard  9756:       strcpy(line,stra);
1.223     brouard  9757:     } /* End loop on waves */
1.225     brouard  9758:     
1.223     brouard  9759:     /* Date of death */
1.136     brouard  9760:     cutv(stra, strb,line,' '); 
1.169     brouard  9761:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9762:     }
1.169     brouard  9763:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9764:       month=99;
                   9765:       year=9999;
                   9766:     }else{
1.141     brouard  9767:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9768:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9769:       return 1;
1.136     brouard  9770:     }
                   9771:     andc[i]=(double) year; 
                   9772:     moisdc[i]=(double) month; 
                   9773:     strcpy(line,stra);
                   9774:     
1.223     brouard  9775:     /* Date of birth */
1.136     brouard  9776:     cutv(stra, strb,line,' '); 
1.169     brouard  9777:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9778:     }
1.169     brouard  9779:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9780:       month=99;
                   9781:       year=9999;
                   9782:     }else{
1.141     brouard  9783:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9784:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9785:       return 1;
1.136     brouard  9786:     }
                   9787:     if (year==9999) {
1.141     brouard  9788:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9789:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9790:       return 1;
                   9791:       
1.136     brouard  9792:     }
                   9793:     annais[i]=(double)(year);
1.302     brouard  9794:     moisnais[i]=(double)(month);
                   9795:     for (j=1;j<=maxwav;j++){
                   9796:       if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){
                   9797:        printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j,(int)moisnais[i],(int)annais[i]);
                   9798:        fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j, (int)moisnais[i],(int)annais[i]);
                   9799:       }
                   9800:     }
                   9801: 
1.136     brouard  9802:     strcpy(line,stra);
1.225     brouard  9803:     
1.223     brouard  9804:     /* Sample weight */
1.136     brouard  9805:     cutv(stra, strb,line,' '); 
                   9806:     errno=0;
                   9807:     dval=strtod(strb,&endptr); 
                   9808:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9809:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9810:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9811:       fflush(ficlog);
                   9812:       return 1;
                   9813:     }
                   9814:     weight[i]=dval; 
                   9815:     strcpy(line,stra);
1.225     brouard  9816:     
1.223     brouard  9817:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9818:       cutv(stra, strb, line, ' '); 
                   9819:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9820:        lval=-1;
1.311     brouard  9821:        coqvar[iv][i]=NAN; 
                   9822:        covar[ncovcol+iv][i]=NAN; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9823:       }else{
1.225     brouard  9824:        errno=0;
                   9825:        /* what_kind_of_number(strb); */
                   9826:        dval=strtod(strb,&endptr);
                   9827:        /* if(strb != endptr && *endptr == '\0') */
                   9828:        /*   dval=dlval; */
                   9829:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9830:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9831:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9832:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9833:          return 1;
                   9834:        }
                   9835:        coqvar[iv][i]=dval; 
1.226     brouard  9836:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9837:       }
                   9838:       strcpy(line,stra);
                   9839:     }/* end loop nqv */
1.136     brouard  9840:     
1.223     brouard  9841:     /* Covariate values */
1.136     brouard  9842:     for (j=ncovcol;j>=1;j--){
                   9843:       cutv(stra, strb,line,' '); 
1.223     brouard  9844:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9845:        lval=-1;
1.136     brouard  9846:       }else{
1.225     brouard  9847:        errno=0;
                   9848:        lval=strtol(strb,&endptr,10); 
                   9849:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9850:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9851:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9852:          return 1;
                   9853:        }
1.136     brouard  9854:       }
                   9855:       if(lval <-1 || lval >1){
1.225     brouard  9856:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9857:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9858:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9859:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9860:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9861:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9862:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9863:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9864:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9865:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9866:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9867:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9868:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9869:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9870:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9871:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9872:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9873:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9874:        return 1;
1.136     brouard  9875:       }
                   9876:       covar[j][i]=(double)(lval);
                   9877:       strcpy(line,stra);
                   9878:     }  
                   9879:     lstra=strlen(stra);
1.225     brouard  9880:     
1.136     brouard  9881:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9882:       stratrunc = &(stra[lstra-9]);
                   9883:       num[i]=atol(stratrunc);
                   9884:     }
                   9885:     else
                   9886:       num[i]=atol(stra);
                   9887:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9888:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9889:     
                   9890:     i=i+1;
                   9891:   } /* End loop reading  data */
1.225     brouard  9892:   
1.136     brouard  9893:   *imax=i-1; /* Number of individuals */
                   9894:   fclose(fic);
1.225     brouard  9895:   
1.136     brouard  9896:   return (0);
1.164     brouard  9897:   /* endread: */
1.225     brouard  9898:   printf("Exiting readdata: ");
                   9899:   fclose(fic);
                   9900:   return (1);
1.223     brouard  9901: }
1.126     brouard  9902: 
1.234     brouard  9903: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9904:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9905:   while (*p2 == ' ')
1.234     brouard  9906:     p2++; 
                   9907:   /* while ((*p1++ = *p2++) !=0) */
                   9908:   /*   ; */
                   9909:   /* do */
                   9910:   /*   while (*p2 == ' ') */
                   9911:   /*     p2++; */
                   9912:   /* while (*p1++ == *p2++); */
                   9913:   *stri=p2; 
1.145     brouard  9914: }
                   9915: 
1.235     brouard  9916: int decoderesult ( char resultline[], int nres)
1.230     brouard  9917: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9918: {
1.235     brouard  9919:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9920:   char resultsav[MAXLINE];
1.234     brouard  9921:   int resultmodel[MAXLINE];
                   9922:   int modelresult[MAXLINE];
1.230     brouard  9923:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9924: 
1.234     brouard  9925:   removefirstspace(&resultline);
1.230     brouard  9926: 
                   9927:   if (strstr(resultline,"v") !=0){
                   9928:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9929:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9930:     return 1;
                   9931:   }
                   9932:   trimbb(resultsav, resultline);
                   9933:   if (strlen(resultsav) >1){
                   9934:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9935:   }
1.253     brouard  9936:   if(j == 0){ /* Resultline but no = */
                   9937:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9938:     return (0);
                   9939:   }
1.234     brouard  9940:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
1.318     brouard  9941:     printf("ERROR: the number of variables in this result line, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
1.310     brouard  9942:     fprintf(ficlog,"ERROR: the number of variables in the resultline, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
1.234     brouard  9943:   }
                   9944:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9945:     if(nbocc(resultsav,'=') >1){
1.318     brouard  9946:       cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' (stra is the rest of the resultline to be analyzed in the next loop *//*     resultsav= "V4=1 V5=25.1 V3=0" stra= "V5=25.1 V3=0" strb= "V4=1" */
                   9947:       cutl(strc,strd,strb,'=');  /* strb:"V4=1" strc="1" strd="V4" */
1.234     brouard  9948:     }else
                   9949:       cutl(strc,strd,resultsav,'=');
1.318     brouard  9950:     Tvalsel[k]=atof(strc); /* 1 */ /* Tvalsel of k is the float value of the kth covariate appearing in this result line */
1.234     brouard  9951:     
1.230     brouard  9952:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
1.318     brouard  9953:     Tvarsel[k]=atoi(strc);  /* 4 */ /* Tvarsel is the id of the kth covariate in the result line Tvarsel[1] in "V4=1.." is 4.*/
1.230     brouard  9954:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9955:     /* cptcovsel++;     */
                   9956:     if (nbocc(stra,'=') >0)
                   9957:       strcpy(resultsav,stra); /* and analyzes it */
                   9958:   }
1.235     brouard  9959:   /* Checking for missing or useless values in comparison of current model needs */
1.318     brouard  9960:   for(k1=1; k1<= cptcovt ;k1++){ /* Loop on model. model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9961:     if(Typevar[k1]==0){ /* Single covariate in model *//*0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.234     brouard  9962:       match=0;
1.318     brouard  9963:       for(k2=1; k2 <=j;k2++){/* Loop on resultline. In result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9964:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar is coming from the model, Tvarsel from the result. Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9965:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.318     brouard  9966:          match=1; /* modelresult of k2 variable of resultline is identical to k1 variable of the model good */
1.234     brouard  9967:          break;
                   9968:        }
                   9969:       }
                   9970:       if(match == 0){
1.310     brouard  9971:        printf("Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9972:        fprintf(ficlog,"Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9973:        return 1;
1.234     brouard  9974:       }
                   9975:     }
                   9976:   }
1.235     brouard  9977:   /* Checking for missing or useless values in comparison of current model needs */
1.318     brouard  9978:   for(k2=1; k2 <=j;k2++){ /* Loop on resultline variables: result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9979:     match=0;
1.318     brouard  9980:     for(k1=1; k1<= cptcovt ;k1++){ /* loop on model: model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.235     brouard  9981:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9982:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.318     brouard  9983:          resultmodel[k1]=k2;  /* k2th variable of the model corresponds to k1 variable of the model. resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9984:          ++match;
                   9985:        }
                   9986:       }
                   9987:     }
                   9988:     if(match == 0){
                   9989:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
1.310     brouard  9990:       fprintf(ficlog,"Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9991:       return 1;
1.234     brouard  9992:     }else if(match > 1){
                   9993:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
1.310     brouard  9994:       fprintf(ficlog,"Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9995:       return 1;
1.234     brouard  9996:     }
                   9997:   }
1.235     brouard  9998:       
1.234     brouard  9999:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  10000:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10001:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   10002:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   10003:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   10004:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   10005:   /*    1 0 0 0 */
                   10006:   /*    2 1 0 0 */
                   10007:   /*    3 0 1 0 */ 
                   10008:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   10009:   /*    5 0 0 1 */
                   10010:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   10011:   /*    7 0 1 1 */
                   10012:   /*    8 1 1 1 */
1.237     brouard  10013:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   10014:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   10015:   /* V5*age V5 known which value for nres?  */
                   10016:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.318     brouard  10017:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* loop on model line */
1.235     brouard  10018:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  10019:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  10020:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   10021:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  10022:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   10023:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   10024:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  10025:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   10026:       k4++;;
                   10027:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
1.318     brouard  10028:       k3q= resultmodel[k1]; /* resultmodel[1(V5)] = 25.1=k3q */
                   10029:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[1]]= Tvarsel[1] = 4=k2 */
1.237     brouard  10030:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   10031:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   10032:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  10033:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   10034:       k4q++;;
                   10035:     }
                   10036:   }
1.234     brouard  10037:   
1.235     brouard  10038:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  10039:   return (0);
                   10040: }
1.235     brouard  10041: 
1.230     brouard  10042: int decodemodel( char model[], int lastobs)
                   10043:  /**< This routine decodes the model and returns:
1.224     brouard  10044:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   10045:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   10046:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   10047:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   10048:        * - cptcovage number of covariates with age*products =2
                   10049:        * - cptcovs number of simple covariates
                   10050:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   10051:        *     which is a new column after the 9 (ncovcol) variables. 
1.319     brouard  10052:        * - if k is a product Vn*Vm, covar[k][i] is filled with correct values for each individual
1.224     brouard  10053:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   10054:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   10055:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   10056:        */
1.319     brouard  10057: /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1, Tage[1]=2 */
1.136     brouard  10058: {
1.238     brouard  10059:   int i, j, k, ks, v;
1.227     brouard  10060:   int  j1, k1, k2, k3, k4;
1.136     brouard  10061:   char modelsav[80];
1.145     brouard  10062:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  10063:   char *strpt;
1.136     brouard  10064: 
1.145     brouard  10065:   /*removespace(model);*/
1.136     brouard  10066:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  10067:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  10068:     if (strstr(model,"AGE") !=0){
1.192     brouard  10069:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   10070:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  10071:       return 1;
                   10072:     }
1.141     brouard  10073:     if (strstr(model,"v") !=0){
                   10074:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   10075:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   10076:       return 1;
                   10077:     }
1.187     brouard  10078:     strcpy(modelsav,model); 
                   10079:     if ((strpt=strstr(model,"age*age")) !=0){
                   10080:       printf(" strpt=%s, model=%s\n",strpt, model);
                   10081:       if(strpt != model){
1.234     brouard  10082:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  10083:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  10084:  corresponding column of parameters.\n",model);
1.234     brouard  10085:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  10086:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  10087:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  10088:        return 1;
1.225     brouard  10089:       }
1.187     brouard  10090:       nagesqr=1;
                   10091:       if (strstr(model,"+age*age") !=0)
1.234     brouard  10092:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  10093:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  10094:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  10095:       else 
1.234     brouard  10096:        substrchaine(modelsav, model, "age*age");
1.187     brouard  10097:     }else
                   10098:       nagesqr=0;
                   10099:     if (strlen(modelsav) >1){
                   10100:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   10101:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  10102:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  10103:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  10104:                     * cst, age and age*age 
                   10105:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   10106:       /* including age products which are counted in cptcovage.
                   10107:        * but the covariates which are products must be treated 
                   10108:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  10109:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   10110:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  10111:       
                   10112:       
1.187     brouard  10113:       /*   Design
                   10114:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   10115:        *  <          ncovcol=8                >
                   10116:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   10117:        *   k=  1    2      3       4     5       6      7        8
                   10118:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   10119:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  10120:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   10121:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  10122:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   10123:        *  Tage[++cptcovage]=k
                   10124:        *       if products, new covar are created after ncovcol with k1
                   10125:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   10126:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   10127:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   10128:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   10129:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   10130:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   10131:        *  <          ncovcol=8                >
                   10132:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   10133:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   10134:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
1.319     brouard  10135:        * p Tvar[1]@12={2,   1,     3,      3,  11,     10,     8,       8,   7,   8,   5,  6}
1.187     brouard  10136:        * p Tprod[1]@2={                         6, 5}
                   10137:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   10138:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   10139:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
1.319     brouard  10140:        *How to reorganize? Tvars(orted)
1.187     brouard  10141:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   10142:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   10143:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   10144:        * Struct []
                   10145:        */
1.225     brouard  10146:       
1.187     brouard  10147:       /* This loop fills the array Tvar from the string 'model'.*/
                   10148:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   10149:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   10150:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   10151:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   10152:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   10153:       /*       k=1 Tvar[1]=2 (from V2) */
                   10154:       /*       k=5 Tvar[5] */
                   10155:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  10156:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  10157:       /*       } */
1.198     brouard  10158:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  10159:       /*
                   10160:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  10161:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   10162:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   10163:       }
1.187     brouard  10164:       cptcovage=0;
1.319     brouard  10165:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model line */
                   10166:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' cutl from left to right
                   10167:                                         modelsav==V2+V1+V5*age+V4+V3*age strb=V3*age stra=V2+V1V5*age+V4 */    /* <model> "V5+V4+V3+V4*V3+V5*age+V1*age+V1" strb="V5" stra="V4+V3+V4*V3+V5*age+V1*age+V1" */
                   10168:        if (nbocc(modelsav,'+')==0)
                   10169:          strcpy(strb,modelsav); /* and analyzes it */
1.234     brouard  10170:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   10171:        /*scanf("%d",i);*/
1.319     brouard  10172:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V5*age+ V4+V3*age strb=V3*age */
                   10173:          cutl(strc,strd,strb,'*'); /**< k=1 strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
1.234     brouard  10174:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   10175:            /* covar is not filled and then is empty */
                   10176:            cptcovprod--;
                   10177:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
1.319     brouard  10178:            Tvar[k]=atoi(stre);  /* V2+V1+V5*age+V4+V3*age Tvar[5]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
1.234     brouard  10179:            Typevar[k]=1;  /* 1 for age product */
1.319     brouard  10180:            cptcovage++; /* Counts the number of covariates which include age as a product */
                   10181:            Tage[cptcovage]=k;  /*  V2+V1+V4+V3*age Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
1.234     brouard  10182:            /*printf("stre=%s ", stre);*/
                   10183:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   10184:            cptcovprod--;
                   10185:            cutl(stre,strb,strc,'V');
                   10186:            Tvar[k]=atoi(stre);
                   10187:            Typevar[k]=1;  /* 1 for age product */
                   10188:            cptcovage++;
                   10189:            Tage[cptcovage]=k;
                   10190:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   10191:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   10192:            cptcovn++;
                   10193:            cptcovprodnoage++;k1++;
                   10194:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   10195:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   10196:                                                because this model-covariate is a construction we invent a new column
                   10197:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
1.319     brouard  10198:                                                If already ncovcol=4 and model=V2 + V1 +V1*V4 +age*V3 +V3*V2
                   10199:                                                thus after V4 we invent V5 and V6 because age*V3 will be computed in 4
                   10200:                                                Tvar[3=V1*V4]=4+1=5 Tvar[5=V3*V2]=4 + 2= 6, Tvar[4=age*V3]=4 etc */
1.234     brouard  10201:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   10202:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   10203:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
1.319     brouard  10204:            Tposprod[k]=k1; /* Tposprod[3]=1, Tposprod[2]=5 */
1.234     brouard  10205:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   10206:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   10207:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   10208:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   10209:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  10210:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  10211:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   10212:            for (i=1; i<=lastobs;i++){
                   10213:              /* Computes the new covariate which is a product of
                   10214:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   10215:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   10216:            }
                   10217:          } /* End age is not in the model */
                   10218:        } /* End if model includes a product */
1.319     brouard  10219:        else { /* not a product */
1.234     brouard  10220:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   10221:          /*  scanf("%d",i);*/
                   10222:          cutl(strd,strc,strb,'V');
                   10223:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   10224:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   10225:          Tvar[k]=atoi(strd);
                   10226:          Typevar[k]=0;  /* 0 for simple covariates */
                   10227:        }
                   10228:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  10229:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  10230:                                  scanf("%d",i);*/
1.187     brouard  10231:       } /* end of loop + on total covariates */
                   10232:     } /* end if strlen(modelsave == 0) age*age might exist */
                   10233:   } /* end if strlen(model == 0) */
1.136     brouard  10234:   
                   10235:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   10236:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  10237:   
1.136     brouard  10238:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  10239:      printf("cptcovprod=%d ", cptcovprod);
                   10240:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   10241:      scanf("%d ",i);*/
                   10242: 
                   10243: 
1.230     brouard  10244: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   10245:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  10246: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   10247:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   10248:    k =           1    2   3     4       5       6      7      8        9
                   10249:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
1.319     brouard  10250:    Typevar[k]=   0    0   0     2       1       0      2      1        0
1.227     brouard  10251:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   10252:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   10253:          Tmodelind[combination of covar]=k;
1.225     brouard  10254: */  
                   10255: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  10256:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  10257:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  10258:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.318     brouard  10259:   printf("Model=1+age+%s\n\
1.227     brouard  10260: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   10261: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   10262: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.318     brouard  10263:   fprintf(ficlog,"Model=1+age+%s\n\
1.227     brouard  10264: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   10265: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   10266: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  10267:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  10268:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   10269:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  10270:       Fixed[k]= 0;
                   10271:       Dummy[k]= 0;
1.225     brouard  10272:       ncoveff++;
1.232     brouard  10273:       ncovf++;
1.234     brouard  10274:       nsd++;
                   10275:       modell[k].maintype= FTYPE;
                   10276:       TvarsD[nsd]=Tvar[k];
                   10277:       TvarsDind[nsd]=k;
                   10278:       TvarF[ncovf]=Tvar[k];
                   10279:       TvarFind[ncovf]=k;
                   10280:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10281:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10282:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   10283:       Fixed[k]= 0;
                   10284:       Dummy[k]= 0;
                   10285:       ncoveff++;
                   10286:       ncovf++;
                   10287:       modell[k].maintype= FTYPE;
                   10288:       TvarF[ncovf]=Tvar[k];
                   10289:       TvarFind[ncovf]=k;
1.230     brouard  10290:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  10291:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  10292:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  10293:       Fixed[k]= 0;
                   10294:       Dummy[k]= 1;
1.230     brouard  10295:       nqfveff++;
1.234     brouard  10296:       modell[k].maintype= FTYPE;
                   10297:       modell[k].subtype= FQ;
                   10298:       nsq++;
                   10299:       TvarsQ[nsq]=Tvar[k];
                   10300:       TvarsQind[nsq]=k;
1.232     brouard  10301:       ncovf++;
1.234     brouard  10302:       TvarF[ncovf]=Tvar[k];
                   10303:       TvarFind[ncovf]=k;
1.231     brouard  10304:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  10305:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  10306:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  10307:       Fixed[k]= 1;
                   10308:       Dummy[k]= 0;
1.225     brouard  10309:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  10310:       modell[k].maintype= VTYPE;
                   10311:       modell[k].subtype= VD;
                   10312:       nsd++;
                   10313:       TvarsD[nsd]=Tvar[k];
                   10314:       TvarsDind[nsd]=k;
                   10315:       ncovv++; /* Only simple time varying variables */
                   10316:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10317:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10318:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   10319:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  10320:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   10321:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  10322:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  10323:       Fixed[k]= 1;
                   10324:       Dummy[k]= 1;
                   10325:       nqtveff++;
                   10326:       modell[k].maintype= VTYPE;
                   10327:       modell[k].subtype= VQ;
                   10328:       ncovv++; /* Only simple time varying variables */
                   10329:       nsq++;
1.319     brouard  10330:       TvarsQ[nsq]=Tvar[k]; /* k=1 Tvar=5 nsq=1 TvarsQ[1]=5 */
1.234     brouard  10331:       TvarsQind[nsq]=k;
                   10332:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10333:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10334:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   10335:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  10336:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   10337:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   10338:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  10339:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  10340:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  10341:       ncova++;
                   10342:       TvarA[ncova]=Tvar[k];
                   10343:       TvarAind[ncova]=k;
1.231     brouard  10344:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  10345:        Fixed[k]= 2;
                   10346:        Dummy[k]= 2;
                   10347:        modell[k].maintype= ATYPE;
                   10348:        modell[k].subtype= APFD;
                   10349:        /* ncoveff++; */
1.227     brouard  10350:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  10351:        Fixed[k]= 2;
                   10352:        Dummy[k]= 3;
                   10353:        modell[k].maintype= ATYPE;
                   10354:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   10355:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  10356:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  10357:        Fixed[k]= 3;
                   10358:        Dummy[k]= 2;
                   10359:        modell[k].maintype= ATYPE;
                   10360:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   10361:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  10362:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10363:        Fixed[k]= 3;
                   10364:        Dummy[k]= 3;
                   10365:        modell[k].maintype= ATYPE;
                   10366:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   10367:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  10368:       }
                   10369:     }else if (Typevar[k] == 2) {  /* product without age */
                   10370:       k1=Tposprod[k];
                   10371:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  10372:        if(Tvard[k1][2] <=ncovcol){
                   10373:          Fixed[k]= 1;
                   10374:          Dummy[k]= 0;
                   10375:          modell[k].maintype= FTYPE;
                   10376:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   10377:          ncovf++; /* Fixed variables without age */
                   10378:          TvarF[ncovf]=Tvar[k];
                   10379:          TvarFind[ncovf]=k;
                   10380:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10381:          Fixed[k]= 0;  /* or 2 ?*/
                   10382:          Dummy[k]= 1;
                   10383:          modell[k].maintype= FTYPE;
                   10384:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   10385:          ncovf++; /* Varying variables without age */
                   10386:          TvarF[ncovf]=Tvar[k];
                   10387:          TvarFind[ncovf]=k;
                   10388:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10389:          Fixed[k]= 1;
                   10390:          Dummy[k]= 0;
                   10391:          modell[k].maintype= VTYPE;
                   10392:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   10393:          ncovv++; /* Varying variables without age */
                   10394:          TvarV[ncovv]=Tvar[k];
                   10395:          TvarVind[ncovv]=k;
                   10396:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10397:          Fixed[k]= 1;
                   10398:          Dummy[k]= 1;
                   10399:          modell[k].maintype= VTYPE;
                   10400:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   10401:          ncovv++; /* Varying variables without age */
                   10402:          TvarV[ncovv]=Tvar[k];
                   10403:          TvarVind[ncovv]=k;
                   10404:        }
1.227     brouard  10405:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  10406:        if(Tvard[k1][2] <=ncovcol){
                   10407:          Fixed[k]= 0;  /* or 2 ?*/
                   10408:          Dummy[k]= 1;
                   10409:          modell[k].maintype= FTYPE;
                   10410:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   10411:          ncovf++; /* Fixed variables without age */
                   10412:          TvarF[ncovf]=Tvar[k];
                   10413:          TvarFind[ncovf]=k;
                   10414:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10415:          Fixed[k]= 1;
                   10416:          Dummy[k]= 1;
                   10417:          modell[k].maintype= VTYPE;
                   10418:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   10419:          ncovv++; /* Varying variables without age */
                   10420:          TvarV[ncovv]=Tvar[k];
                   10421:          TvarVind[ncovv]=k;
                   10422:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10423:          Fixed[k]= 1;
                   10424:          Dummy[k]= 1;
                   10425:          modell[k].maintype= VTYPE;
                   10426:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   10427:          ncovv++; /* Varying variables without age */
                   10428:          TvarV[ncovv]=Tvar[k];
                   10429:          TvarVind[ncovv]=k;
                   10430:          ncovv++; /* Varying variables without age */
                   10431:          TvarV[ncovv]=Tvar[k];
                   10432:          TvarVind[ncovv]=k;
                   10433:        }
1.227     brouard  10434:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  10435:        if(Tvard[k1][2] <=ncovcol){
                   10436:          Fixed[k]= 1;
                   10437:          Dummy[k]= 1;
                   10438:          modell[k].maintype= VTYPE;
                   10439:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   10440:          ncovv++; /* Varying variables without age */
                   10441:          TvarV[ncovv]=Tvar[k];
                   10442:          TvarVind[ncovv]=k;
                   10443:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10444:          Fixed[k]= 1;
                   10445:          Dummy[k]= 1;
                   10446:          modell[k].maintype= VTYPE;
                   10447:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   10448:          ncovv++; /* Varying variables without age */
                   10449:          TvarV[ncovv]=Tvar[k];
                   10450:          TvarVind[ncovv]=k;
                   10451:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10452:          Fixed[k]= 1;
                   10453:          Dummy[k]= 0;
                   10454:          modell[k].maintype= VTYPE;
                   10455:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   10456:          ncovv++; /* Varying variables without age */
                   10457:          TvarV[ncovv]=Tvar[k];
                   10458:          TvarVind[ncovv]=k;
                   10459:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10460:          Fixed[k]= 1;
                   10461:          Dummy[k]= 1;
                   10462:          modell[k].maintype= VTYPE;
                   10463:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   10464:          ncovv++; /* Varying variables without age */
                   10465:          TvarV[ncovv]=Tvar[k];
                   10466:          TvarVind[ncovv]=k;
                   10467:        }
1.227     brouard  10468:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10469:        if(Tvard[k1][2] <=ncovcol){
                   10470:          Fixed[k]= 1;
                   10471:          Dummy[k]= 1;
                   10472:          modell[k].maintype= VTYPE;
                   10473:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   10474:          ncovv++; /* Varying variables without age */
                   10475:          TvarV[ncovv]=Tvar[k];
                   10476:          TvarVind[ncovv]=k;
                   10477:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10478:          Fixed[k]= 1;
                   10479:          Dummy[k]= 1;
                   10480:          modell[k].maintype= VTYPE;
                   10481:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   10482:          ncovv++; /* Varying variables without age */
                   10483:          TvarV[ncovv]=Tvar[k];
                   10484:          TvarVind[ncovv]=k;
                   10485:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10486:          Fixed[k]= 1;
                   10487:          Dummy[k]= 1;
                   10488:          modell[k].maintype= VTYPE;
                   10489:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   10490:          ncovv++; /* Varying variables without age */
                   10491:          TvarV[ncovv]=Tvar[k];
                   10492:          TvarVind[ncovv]=k;
                   10493:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10494:          Fixed[k]= 1;
                   10495:          Dummy[k]= 1;
                   10496:          modell[k].maintype= VTYPE;
                   10497:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10498:          ncovv++; /* Varying variables without age */
                   10499:          TvarV[ncovv]=Tvar[k];
                   10500:          TvarVind[ncovv]=k;
                   10501:        }
1.227     brouard  10502:       }else{
1.240     brouard  10503:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10504:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10505:       } /*end k1*/
1.225     brouard  10506:     }else{
1.226     brouard  10507:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10508:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10509:     }
1.227     brouard  10510:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10511:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10512:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10513:   }
                   10514:   /* Searching for doublons in the model */
                   10515:   for(k1=1; k1<= cptcovt;k1++){
                   10516:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10517:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10518:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10519:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10520:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10521:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10522:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10523:            return(1);
                   10524:          }
                   10525:        }else if (Typevar[k1] ==2){
                   10526:          k3=Tposprod[k1];
                   10527:          k4=Tposprod[k2];
                   10528:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10529:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10530:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10531:            return(1);
                   10532:          }
                   10533:        }
1.227     brouard  10534:       }
                   10535:     }
1.225     brouard  10536:   }
                   10537:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10538:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10539:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10540:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10541:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10542:   /*endread:*/
1.225     brouard  10543:   printf("Exiting decodemodel: ");
                   10544:   return (1);
1.136     brouard  10545: }
                   10546: 
1.169     brouard  10547: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10548: {/* Check ages at death */
1.136     brouard  10549:   int i, m;
1.218     brouard  10550:   int firstone=0;
                   10551:   
1.136     brouard  10552:   for (i=1; i<=imx; i++) {
                   10553:     for(m=2; (m<= maxwav); m++) {
                   10554:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10555:        anint[m][i]=9999;
1.216     brouard  10556:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10557:          s[m][i]=-1;
1.136     brouard  10558:       }
                   10559:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10560:        *nberr = *nberr + 1;
1.218     brouard  10561:        if(firstone == 0){
                   10562:          firstone=1;
1.260     brouard  10563:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10564:        }
1.262     brouard  10565:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10566:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10567:       }
                   10568:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10569:        (*nberr)++;
1.259     brouard  10570:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10571:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10572:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10573:       }
                   10574:     }
                   10575:   }
                   10576: 
                   10577:   for (i=1; i<=imx; i++)  {
                   10578:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10579:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10580:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10581:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10582:          if(agedc[i]>0){
                   10583:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10584:              agev[m][i]=agedc[i];
1.214     brouard  10585:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10586:            }else {
1.136     brouard  10587:              if ((int)andc[i]!=9999){
                   10588:                nbwarn++;
                   10589:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10590:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10591:                agev[m][i]=-1;
                   10592:              }
                   10593:            }
1.169     brouard  10594:          } /* agedc > 0 */
1.214     brouard  10595:        } /* end if */
1.136     brouard  10596:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10597:                                 years but with the precision of a month */
                   10598:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10599:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10600:            agev[m][i]=1;
                   10601:          else if(agev[m][i] < *agemin){ 
                   10602:            *agemin=agev[m][i];
                   10603:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10604:          }
                   10605:          else if(agev[m][i] >*agemax){
                   10606:            *agemax=agev[m][i];
1.156     brouard  10607:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10608:          }
                   10609:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10610:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10611:        } /* en if 9*/
1.136     brouard  10612:        else { /* =9 */
1.214     brouard  10613:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10614:          agev[m][i]=1;
                   10615:          s[m][i]=-1;
                   10616:        }
                   10617:       }
1.214     brouard  10618:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10619:        agev[m][i]=1;
1.214     brouard  10620:       else{
                   10621:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10622:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10623:        agev[m][i]=0;
                   10624:       }
                   10625:     } /* End for lastpass */
                   10626:   }
1.136     brouard  10627:     
                   10628:   for (i=1; i<=imx; i++)  {
                   10629:     for(m=firstpass; (m<=lastpass); m++){
                   10630:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10631:        (*nberr)++;
1.136     brouard  10632:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10633:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10634:        return 1;
                   10635:       }
                   10636:     }
                   10637:   }
                   10638: 
                   10639:   /*for (i=1; i<=imx; i++){
                   10640:   for (m=firstpass; (m<lastpass); m++){
                   10641:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10642: }
                   10643: 
                   10644: }*/
                   10645: 
                   10646: 
1.139     brouard  10647:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10648:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10649: 
                   10650:   return (0);
1.164     brouard  10651:  /* endread:*/
1.136     brouard  10652:     printf("Exiting calandcheckages: ");
                   10653:     return (1);
                   10654: }
                   10655: 
1.172     brouard  10656: #if defined(_MSC_VER)
                   10657: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10658: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10659: //#include "stdafx.h"
                   10660: //#include <stdio.h>
                   10661: //#include <tchar.h>
                   10662: //#include <windows.h>
                   10663: //#include <iostream>
                   10664: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10665: 
                   10666: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10667: 
                   10668: BOOL IsWow64()
                   10669: {
                   10670:        BOOL bIsWow64 = FALSE;
                   10671: 
                   10672:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10673:        //  (HANDLE, PBOOL);
                   10674: 
                   10675:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10676: 
                   10677:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10678:        const char funcName[] = "IsWow64Process";
                   10679:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10680:                GetProcAddress(module, funcName);
                   10681: 
                   10682:        if (NULL != fnIsWow64Process)
                   10683:        {
                   10684:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10685:                        &bIsWow64))
                   10686:                        //throw std::exception("Unknown error");
                   10687:                        printf("Unknown error\n");
                   10688:        }
                   10689:        return bIsWow64 != FALSE;
                   10690: }
                   10691: #endif
1.177     brouard  10692: 
1.191     brouard  10693: void syscompilerinfo(int logged)
1.292     brouard  10694: {
                   10695: #include <stdint.h>
                   10696: 
                   10697:   /* #include "syscompilerinfo.h"*/
1.185     brouard  10698:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10699:    /* /GS /W3 /Gy
                   10700:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10701:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10702:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10703:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10704:    */ 
                   10705:    /* 64 bits */
1.185     brouard  10706:    /*
                   10707:      /GS /W3 /Gy
                   10708:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10709:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10710:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10711:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10712:    /* Optimization are useless and O3 is slower than O2 */
                   10713:    /*
                   10714:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10715:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10716:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10717:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10718:    */
1.186     brouard  10719:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10720:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10721:       /PDB:"visual studio
                   10722:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10723:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10724:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10725:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10726:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10727:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10728:       uiAccess='false'"
                   10729:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10730:       /NOLOGO /TLBID:1
                   10731:    */
1.292     brouard  10732: 
                   10733: 
1.177     brouard  10734: #if defined __INTEL_COMPILER
1.178     brouard  10735: #if defined(__GNUC__)
                   10736:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10737: #endif
1.177     brouard  10738: #elif defined(__GNUC__) 
1.179     brouard  10739: #ifndef  __APPLE__
1.174     brouard  10740: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10741: #endif
1.177     brouard  10742:    struct utsname sysInfo;
1.178     brouard  10743:    int cross = CROSS;
                   10744:    if (cross){
                   10745:           printf("Cross-");
1.191     brouard  10746:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10747:    }
1.174     brouard  10748: #endif
                   10749: 
1.191     brouard  10750:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10751: #if defined(__clang__)
1.191     brouard  10752:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10753: #endif
                   10754: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10755:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10756: #endif
                   10757: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10758:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10759: #endif
                   10760: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10761:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10762: #endif
                   10763: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10764:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10765: #endif
                   10766: #if defined(_MSC_VER)
1.191     brouard  10767:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10768: #endif
                   10769: #if defined(__PGI)
1.191     brouard  10770:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10771: #endif
                   10772: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10773:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10774: #endif
1.191     brouard  10775:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10776:    
1.167     brouard  10777: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10778: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10779:     // Windows (x64 and x86)
1.191     brouard  10780:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10781: #elif __unix__ // all unices, not all compilers
                   10782:     // Unix
1.191     brouard  10783:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10784: #elif __linux__
                   10785:     // linux
1.191     brouard  10786:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10787: #elif __APPLE__
1.174     brouard  10788:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10789:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10790: #endif
                   10791: 
                   10792: /*  __MINGW32__          */
                   10793: /*  __CYGWIN__  */
                   10794: /* __MINGW64__  */
                   10795: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10796: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10797: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10798: /* _WIN64  // Defined for applications for Win64. */
                   10799: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10800: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10801: 
1.167     brouard  10802: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10803:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10804: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10805:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10806: #else
1.191     brouard  10807:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10808: #endif
                   10809: 
1.169     brouard  10810: #if defined(__GNUC__)
                   10811: # if defined(__GNUC_PATCHLEVEL__)
                   10812: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10813:                             + __GNUC_MINOR__ * 100 \
                   10814:                             + __GNUC_PATCHLEVEL__)
                   10815: # else
                   10816: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10817:                             + __GNUC_MINOR__ * 100)
                   10818: # endif
1.174     brouard  10819:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10820:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10821: 
                   10822:    if (uname(&sysInfo) != -1) {
                   10823:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10824:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10825:    }
                   10826:    else
                   10827:       perror("uname() error");
1.179     brouard  10828:    //#ifndef __INTEL_COMPILER 
                   10829: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10830:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10831:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10832: #endif
1.169     brouard  10833: #endif
1.172     brouard  10834: 
1.286     brouard  10835:    //   void main ()
1.172     brouard  10836:    //   {
1.169     brouard  10837: #if defined(_MSC_VER)
1.174     brouard  10838:    if (IsWow64()){
1.191     brouard  10839:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10840:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10841:    }
                   10842:    else{
1.191     brouard  10843:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10844:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10845:    }
1.172     brouard  10846:    //     printf("\nPress Enter to continue...");
                   10847:    //     getchar();
                   10848:    //   }
                   10849: 
1.169     brouard  10850: #endif
                   10851:    
1.167     brouard  10852: 
1.219     brouard  10853: }
1.136     brouard  10854: 
1.219     brouard  10855: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10856:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10857:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10858:   /* double ftolpl = 1.e-10; */
1.180     brouard  10859:   double age, agebase, agelim;
1.203     brouard  10860:   double tot;
1.180     brouard  10861: 
1.202     brouard  10862:   strcpy(filerespl,"PL_");
                   10863:   strcat(filerespl,fileresu);
                   10864:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10865:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10866:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10867:   }
1.288     brouard  10868:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10869:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10870:   pstamp(ficrespl);
1.288     brouard  10871:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10872:   fprintf(ficrespl,"#Age ");
                   10873:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10874:   fprintf(ficrespl,"\n");
1.180     brouard  10875:   
1.219     brouard  10876:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10877: 
1.219     brouard  10878:   agebase=ageminpar;
                   10879:   agelim=agemaxpar;
1.180     brouard  10880: 
1.227     brouard  10881:   /* i1=pow(2,ncoveff); */
1.234     brouard  10882:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10883:   if (cptcovn < 1){i1=1;}
1.180     brouard  10884: 
1.238     brouard  10885:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10886:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10887:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10888:        continue;
1.235     brouard  10889: 
1.238     brouard  10890:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10891:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10892:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10893:       /* k=k+1; */
                   10894:       /* to clean */
                   10895:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10896:       fprintf(ficrespl,"#******");
                   10897:       printf("#******");
                   10898:       fprintf(ficlog,"#******");
                   10899:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10900:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10901:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10902:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10903:       }
                   10904:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10905:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10906:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10907:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10908:       }
                   10909:       fprintf(ficrespl,"******\n");
                   10910:       printf("******\n");
                   10911:       fprintf(ficlog,"******\n");
                   10912:       if(invalidvarcomb[k]){
                   10913:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10914:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10915:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10916:        continue;
                   10917:       }
1.219     brouard  10918: 
1.238     brouard  10919:       fprintf(ficrespl,"#Age ");
                   10920:       for(j=1;j<=cptcoveff;j++) {
                   10921:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10922:       }
                   10923:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10924:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10925:     
1.238     brouard  10926:       for (age=agebase; age<=agelim; age++){
                   10927:        /* for (age=agebase; age<=agebase; age++){ */
                   10928:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10929:        fprintf(ficrespl,"%.0f ",age );
                   10930:        for(j=1;j<=cptcoveff;j++)
                   10931:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10932:        tot=0.;
                   10933:        for(i=1; i<=nlstate;i++){
                   10934:          tot +=  prlim[i][i];
                   10935:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10936:        }
                   10937:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10938:       } /* Age */
                   10939:       /* was end of cptcod */
                   10940:     } /* cptcov */
                   10941:   } /* nres */
1.219     brouard  10942:   return 0;
1.180     brouard  10943: }
                   10944: 
1.218     brouard  10945: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10946:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10947:        
                   10948:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10949:    * at any age between ageminpar and agemaxpar
                   10950:         */
1.235     brouard  10951:   int i, j, k, i1, nres=0 ;
1.217     brouard  10952:   /* double ftolpl = 1.e-10; */
                   10953:   double age, agebase, agelim;
                   10954:   double tot;
1.218     brouard  10955:   /* double ***mobaverage; */
                   10956:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10957: 
                   10958:   strcpy(fileresplb,"PLB_");
                   10959:   strcat(fileresplb,fileresu);
                   10960:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10961:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10962:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10963:   }
1.288     brouard  10964:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10965:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10966:   pstamp(ficresplb);
1.288     brouard  10967:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10968:   fprintf(ficresplb,"#Age ");
                   10969:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10970:   fprintf(ficresplb,"\n");
                   10971:   
1.218     brouard  10972:   
                   10973:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10974:   
                   10975:   agebase=ageminpar;
                   10976:   agelim=agemaxpar;
                   10977:   
                   10978:   
1.227     brouard  10979:   i1=pow(2,cptcoveff);
1.218     brouard  10980:   if (cptcovn < 1){i1=1;}
1.227     brouard  10981:   
1.238     brouard  10982:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10983:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10984:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10985:        continue;
                   10986:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10987:       fprintf(ficresplb,"#******");
                   10988:       printf("#******");
                   10989:       fprintf(ficlog,"#******");
                   10990:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10991:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10992:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10993:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10994:       }
                   10995:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10996:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10997:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10998:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10999:       }
                   11000:       fprintf(ficresplb,"******\n");
                   11001:       printf("******\n");
                   11002:       fprintf(ficlog,"******\n");
                   11003:       if(invalidvarcomb[k]){
                   11004:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   11005:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   11006:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   11007:        continue;
                   11008:       }
1.218     brouard  11009:     
1.238     brouard  11010:       fprintf(ficresplb,"#Age ");
                   11011:       for(j=1;j<=cptcoveff;j++) {
                   11012:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11013:       }
                   11014:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   11015:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  11016:     
                   11017:     
1.238     brouard  11018:       for (age=agebase; age<=agelim; age++){
                   11019:        /* for (age=agebase; age<=agebase; age++){ */
                   11020:        if(mobilavproj > 0){
                   11021:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   11022:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  11023:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  11024:        }else if (mobilavproj == 0){
                   11025:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   11026:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   11027:          exit(1);
                   11028:        }else{
                   11029:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  11030:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  11031:          /* printf("TOTOT\n"); */
                   11032:           /* exit(1); */
1.238     brouard  11033:        }
                   11034:        fprintf(ficresplb,"%.0f ",age );
                   11035:        for(j=1;j<=cptcoveff;j++)
                   11036:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11037:        tot=0.;
                   11038:        for(i=1; i<=nlstate;i++){
                   11039:          tot +=  bprlim[i][i];
                   11040:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   11041:        }
                   11042:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   11043:       } /* Age */
                   11044:       /* was end of cptcod */
1.255     brouard  11045:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  11046:     } /* end of any combination */
                   11047:   } /* end of nres */  
1.218     brouard  11048:   /* hBijx(p, bage, fage); */
                   11049:   /* fclose(ficrespijb); */
                   11050:   
                   11051:   return 0;
1.217     brouard  11052: }
1.218     brouard  11053:  
1.180     brouard  11054: int hPijx(double *p, int bage, int fage){
                   11055:     /*------------- h Pij x at various ages ------------*/
                   11056: 
                   11057:   int stepsize;
                   11058:   int agelim;
                   11059:   int hstepm;
                   11060:   int nhstepm;
1.235     brouard  11061:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  11062: 
                   11063:   double agedeb;
                   11064:   double ***p3mat;
                   11065: 
1.201     brouard  11066:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  11067:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   11068:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   11069:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   11070:     }
                   11071:     printf("Computing pij: result on file '%s' \n", filerespij);
                   11072:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   11073:   
                   11074:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   11075:     /*if (stepm<=24) stepsize=2;*/
                   11076: 
                   11077:     agelim=AGESUP;
                   11078:     hstepm=stepsize*YEARM; /* Every year of age */
                   11079:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  11080:                
1.180     brouard  11081:     /* hstepm=1;   aff par mois*/
                   11082:     pstamp(ficrespij);
                   11083:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  11084:     i1= pow(2,cptcoveff);
1.218     brouard  11085:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   11086:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   11087:                /*      k=k+1;  */
1.235     brouard  11088:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11089:     for(k=1; k<=i1;k++){
1.253     brouard  11090:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11091:        continue;
1.183     brouard  11092:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  11093:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  11094:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11095:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   11096:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   11097:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   11098:       }
1.183     brouard  11099:       fprintf(ficrespij,"******\n");
                   11100:       
                   11101:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   11102:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   11103:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   11104:        
                   11105:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  11106:        
1.183     brouard  11107:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   11108:        oldm=oldms;savm=savms;
1.235     brouard  11109:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  11110:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   11111:        for(i=1; i<=nlstate;i++)
                   11112:          for(j=1; j<=nlstate+ndeath;j++)
                   11113:            fprintf(ficrespij," %1d-%1d",i,j);
                   11114:        fprintf(ficrespij,"\n");
                   11115:        for (h=0; h<=nhstepm; h++){
                   11116:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   11117:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  11118:          for(i=1; i<=nlstate;i++)
                   11119:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  11120:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  11121:          fprintf(ficrespij,"\n");
                   11122:        }
1.183     brouard  11123:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   11124:        fprintf(ficrespij,"\n");
                   11125:       }
1.180     brouard  11126:       /*}*/
                   11127:     }
1.218     brouard  11128:     return 0;
1.180     brouard  11129: }
1.218     brouard  11130:  
                   11131:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  11132:     /*------------- h Bij x at various ages ------------*/
                   11133: 
                   11134:   int stepsize;
1.218     brouard  11135:   /* int agelim; */
                   11136:        int ageminl;
1.217     brouard  11137:   int hstepm;
                   11138:   int nhstepm;
1.238     brouard  11139:   int h, i, i1, j, k, nres;
1.218     brouard  11140:        
1.217     brouard  11141:   double agedeb;
                   11142:   double ***p3mat;
1.218     brouard  11143:        
                   11144:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   11145:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   11146:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   11147:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   11148:   }
                   11149:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   11150:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   11151:   
                   11152:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   11153:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  11154:   
1.218     brouard  11155:   /* agelim=AGESUP; */
1.289     brouard  11156:   ageminl=AGEINF; /* was 30 */
1.218     brouard  11157:   hstepm=stepsize*YEARM; /* Every year of age */
                   11158:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   11159:   
                   11160:   /* hstepm=1;   aff par mois*/
                   11161:   pstamp(ficrespijb);
1.255     brouard  11162:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  11163:   i1= pow(2,cptcoveff);
1.218     brouard  11164:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   11165:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   11166:   /*   k=k+1;  */
1.238     brouard  11167:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   11168:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11169:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  11170:        continue;
                   11171:       fprintf(ficrespijb,"\n#****** ");
                   11172:       for(j=1;j<=cptcoveff;j++)
                   11173:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11174:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11175:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11176:       }
                   11177:       fprintf(ficrespijb,"******\n");
1.264     brouard  11178:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  11179:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   11180:        continue;
                   11181:       }
                   11182:       
                   11183:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   11184:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   11185:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
1.297     brouard  11186:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm+0.1)-1; /* Typically 20 years = 20*12/6=40 or 55*12/24=27.5-1.1=>27 */
                   11187:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 or 28*/
1.238     brouard  11188:        
                   11189:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   11190:        
1.266     brouard  11191:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   11192:        /* and memory limitations if stepm is small */
                   11193: 
1.238     brouard  11194:        /* oldm=oldms;savm=savms; */
                   11195:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.325   ! brouard  11196:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);/* Bug valgrind */
1.238     brouard  11197:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  11198:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  11199:        for(i=1; i<=nlstate;i++)
                   11200:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  11201:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  11202:        fprintf(ficrespijb,"\n");
1.238     brouard  11203:        for (h=0; h<=nhstepm; h++){
                   11204:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   11205:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   11206:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   11207:          for(i=1; i<=nlstate;i++)
                   11208:            for(j=1; j<=nlstate+ndeath;j++)
1.325   ! brouard  11209:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);/* Bug valgrind */
1.238     brouard  11210:          fprintf(ficrespijb,"\n");
                   11211:        }
                   11212:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   11213:        fprintf(ficrespijb,"\n");
                   11214:       } /* end age deb */
                   11215:     } /* end combination */
                   11216:   } /* end nres */
1.218     brouard  11217:   return 0;
                   11218:  } /*  hBijx */
1.217     brouard  11219: 
1.180     brouard  11220: 
1.136     brouard  11221: /***********************************************/
                   11222: /**************** Main Program *****************/
                   11223: /***********************************************/
                   11224: 
                   11225: int main(int argc, char *argv[])
                   11226: {
                   11227: #ifdef GSL
                   11228:   const gsl_multimin_fminimizer_type *T;
                   11229:   size_t iteri = 0, it;
                   11230:   int rval = GSL_CONTINUE;
                   11231:   int status = GSL_SUCCESS;
                   11232:   double ssval;
                   11233: #endif
                   11234:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  11235:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   11236:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  11237:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  11238:   int jj, ll, li, lj, lk;
1.136     brouard  11239:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  11240:   int num_filled;
1.136     brouard  11241:   int itimes;
                   11242:   int NDIM=2;
                   11243:   int vpopbased=0;
1.235     brouard  11244:   int nres=0;
1.258     brouard  11245:   int endishere=0;
1.277     brouard  11246:   int noffset=0;
1.274     brouard  11247:   int ncurrv=0; /* Temporary variable */
                   11248:   
1.164     brouard  11249:   char ca[32], cb[32];
1.136     brouard  11250:   /*  FILE *fichtm; *//* Html File */
                   11251:   /* FILE *ficgp;*/ /*Gnuplot File */
                   11252:   struct stat info;
1.191     brouard  11253:   double agedeb=0.;
1.194     brouard  11254: 
                   11255:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  11256:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  11257: 
1.165     brouard  11258:   double fret;
1.191     brouard  11259:   double dum=0.; /* Dummy variable */
1.136     brouard  11260:   double ***p3mat;
1.218     brouard  11261:   /* double ***mobaverage; */
1.319     brouard  11262:   double wald;
1.164     brouard  11263: 
                   11264:   char line[MAXLINE];
1.197     brouard  11265:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   11266: 
1.234     brouard  11267:   char  modeltemp[MAXLINE];
1.230     brouard  11268:   char resultline[MAXLINE];
                   11269:   
1.136     brouard  11270:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  11271:   char *tok, *val; /* pathtot */
1.290     brouard  11272:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  11273:   int c,  h , cpt, c2;
1.191     brouard  11274:   int jl=0;
                   11275:   int i1, j1, jk, stepsize=0;
1.194     brouard  11276:   int count=0;
                   11277: 
1.164     brouard  11278:   int *tab; 
1.136     brouard  11279:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.296     brouard  11280:   /* double anprojd, mprojd, jprojd; /\* For eventual projections *\/ */
                   11281:   /* double anprojf, mprojf, jprojf; */
                   11282:   /* double jintmean,mintmean,aintmean;   */
                   11283:   int prvforecast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11284:   int prvbackcast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11285:   double yrfproj= 10.0; /* Number of years of forward projections */
                   11286:   double yrbproj= 10.0; /* Number of years of backward projections */
                   11287:   int prevbcast=0; /* defined as global for mlikeli and mle, replacing backcast */
1.136     brouard  11288:   int mobilav=0,popforecast=0;
1.191     brouard  11289:   int hstepm=0, nhstepm=0;
1.136     brouard  11290:   int agemortsup;
                   11291:   float  sumlpop=0.;
                   11292:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   11293:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   11294: 
1.191     brouard  11295:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  11296:   double ftolpl=FTOL;
                   11297:   double **prlim;
1.217     brouard  11298:   double **bprlim;
1.317     brouard  11299:   double ***param; /* Matrix of parameters, param[i][j][k] param=ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel) 
                   11300:                     state of origin, state of destination including death, for each covariate: constante, age, and V1 V2 etc. */
1.251     brouard  11301:   double ***paramstart; /* Matrix of starting parameter values */
                   11302:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  11303:   double **matcov; /* Matrix of covariance */
1.203     brouard  11304:   double **hess; /* Hessian matrix */
1.136     brouard  11305:   double ***delti3; /* Scale */
                   11306:   double *delti; /* Scale */
                   11307:   double ***eij, ***vareij;
                   11308:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  11309: 
1.136     brouard  11310:   double *epj, vepp;
1.164     brouard  11311: 
1.273     brouard  11312:   double dateprev1, dateprev2;
1.296     brouard  11313:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0, dateprojd=0, dateprojf=0;
                   11314:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0, datebackd=0, datebackf=0;
                   11315: 
1.217     brouard  11316: 
1.136     brouard  11317:   double **ximort;
1.145     brouard  11318:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  11319:   int *dcwave;
                   11320: 
1.164     brouard  11321:   char z[1]="c";
1.136     brouard  11322: 
                   11323:   /*char  *strt;*/
                   11324:   char strtend[80];
1.126     brouard  11325: 
1.164     brouard  11326: 
1.126     brouard  11327: /*   setlocale (LC_ALL, ""); */
                   11328: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   11329: /*   textdomain (PACKAGE); */
                   11330: /*   setlocale (LC_CTYPE, ""); */
                   11331: /*   setlocale (LC_MESSAGES, ""); */
                   11332: 
                   11333:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  11334:   rstart_time = time(NULL);  
                   11335:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   11336:   start_time = *localtime(&rstart_time);
1.126     brouard  11337:   curr_time=start_time;
1.157     brouard  11338:   /*tml = *localtime(&start_time.tm_sec);*/
                   11339:   /* strcpy(strstart,asctime(&tml)); */
                   11340:   strcpy(strstart,asctime(&start_time));
1.126     brouard  11341: 
                   11342: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  11343: /*  tp.tm_sec = tp.tm_sec +86400; */
                   11344: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  11345: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   11346: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   11347: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  11348: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  11349: /*   strt=asctime(&tmg); */
                   11350: /*   printf("Time(after) =%s",strstart);  */
                   11351: /*  (void) time (&time_value);
                   11352: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   11353: *  tm = *localtime(&time_value);
                   11354: *  strstart=asctime(&tm);
                   11355: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   11356: */
                   11357: 
                   11358:   nberr=0; /* Number of errors and warnings */
                   11359:   nbwarn=0;
1.184     brouard  11360: #ifdef WIN32
                   11361:   _getcwd(pathcd, size);
                   11362: #else
1.126     brouard  11363:   getcwd(pathcd, size);
1.184     brouard  11364: #endif
1.191     brouard  11365:   syscompilerinfo(0);
1.196     brouard  11366:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  11367:   if(argc <=1){
                   11368:     printf("\nEnter the parameter file name: ");
1.205     brouard  11369:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   11370:       printf("ERROR Empty parameter file name\n");
                   11371:       goto end;
                   11372:     }
1.126     brouard  11373:     i=strlen(pathr);
                   11374:     if(pathr[i-1]=='\n')
                   11375:       pathr[i-1]='\0';
1.156     brouard  11376:     i=strlen(pathr);
1.205     brouard  11377:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  11378:       pathr[i-1]='\0';
1.205     brouard  11379:     }
                   11380:     i=strlen(pathr);
                   11381:     if( i==0 ){
                   11382:       printf("ERROR Empty parameter file name\n");
                   11383:       goto end;
                   11384:     }
                   11385:     for (tok = pathr; tok != NULL; ){
1.126     brouard  11386:       printf("Pathr |%s|\n",pathr);
                   11387:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   11388:       printf("val= |%s| pathr=%s\n",val,pathr);
                   11389:       strcpy (pathtot, val);
                   11390:       if(pathr[0] == '\0') break; /* Dirty */
                   11391:     }
                   11392:   }
1.281     brouard  11393:   else if (argc<=2){
                   11394:     strcpy(pathtot,argv[1]);
                   11395:   }
1.126     brouard  11396:   else{
                   11397:     strcpy(pathtot,argv[1]);
1.281     brouard  11398:     strcpy(z,argv[2]);
                   11399:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  11400:   }
                   11401:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   11402:   /*cygwin_split_path(pathtot,path,optionfile);
                   11403:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   11404:   /* cutv(path,optionfile,pathtot,'\\');*/
                   11405: 
                   11406:   /* Split argv[0], imach program to get pathimach */
                   11407:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   11408:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11409:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11410:  /*   strcpy(pathimach,argv[0]); */
                   11411:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   11412:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   11413:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  11414: #ifdef WIN32
                   11415:   _chdir(path); /* Can be a relative path */
                   11416:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   11417: #else
1.126     brouard  11418:   chdir(path); /* Can be a relative path */
1.184     brouard  11419:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   11420: #endif
                   11421:   printf("Current directory %s!\n",pathcd);
1.126     brouard  11422:   strcpy(command,"mkdir ");
                   11423:   strcat(command,optionfilefiname);
                   11424:   if((outcmd=system(command)) != 0){
1.169     brouard  11425:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  11426:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   11427:     /* fclose(ficlog); */
                   11428: /*     exit(1); */
                   11429:   }
                   11430: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   11431: /*     perror("mkdir"); */
                   11432: /*   } */
                   11433: 
                   11434:   /*-------- arguments in the command line --------*/
                   11435: 
1.186     brouard  11436:   /* Main Log file */
1.126     brouard  11437:   strcat(filelog, optionfilefiname);
                   11438:   strcat(filelog,".log");    /* */
                   11439:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   11440:     printf("Problem with logfile %s\n",filelog);
                   11441:     goto end;
                   11442:   }
                   11443:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  11444:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  11445:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   11446:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   11447:  path=%s \n\
                   11448:  optionfile=%s\n\
                   11449:  optionfilext=%s\n\
1.156     brouard  11450:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  11451: 
1.197     brouard  11452:   syscompilerinfo(1);
1.167     brouard  11453: 
1.126     brouard  11454:   printf("Local time (at start):%s",strstart);
                   11455:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   11456:   fflush(ficlog);
                   11457: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  11458: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  11459: 
                   11460:   /* */
                   11461:   strcpy(fileres,"r");
                   11462:   strcat(fileres, optionfilefiname);
1.201     brouard  11463:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  11464:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  11465:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  11466: 
1.186     brouard  11467:   /* Main ---------arguments file --------*/
1.126     brouard  11468: 
                   11469:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  11470:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   11471:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  11472:     fflush(ficlog);
1.149     brouard  11473:     /* goto end; */
                   11474:     exit(70); 
1.126     brouard  11475:   }
                   11476: 
                   11477:   strcpy(filereso,"o");
1.201     brouard  11478:   strcat(filereso,fileresu);
1.126     brouard  11479:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   11480:     printf("Problem with Output resultfile: %s\n", filereso);
                   11481:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   11482:     fflush(ficlog);
                   11483:     goto end;
                   11484:   }
1.278     brouard  11485:       /*-------- Rewriting parameter file ----------*/
                   11486:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   11487:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   11488:   strcat(rfileres,".");    /* */
                   11489:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11490:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   11491:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11492:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   11493:     fflush(ficlog);
                   11494:     goto end;
                   11495:   }
                   11496:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  11497: 
1.278     brouard  11498:                                      
1.126     brouard  11499:   /* Reads comments: lines beginning with '#' */
                   11500:   numlinepar=0;
1.277     brouard  11501:   /* Is it a BOM UTF-8 Windows file? */
                   11502:   /* First parameter line */
1.197     brouard  11503:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  11504:     noffset=0;
                   11505:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   11506:     {
                   11507:       noffset=noffset+3;
                   11508:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11509:     }
1.302     brouard  11510: /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   11511:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
1.277     brouard  11512:     {
                   11513:       noffset=noffset+2;
                   11514:       printf("# File is an UTF16BE BOM file\n");
                   11515:     }
                   11516:     else if( line[0] == 0 && line[1] == 0)
                   11517:     {
                   11518:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11519:        noffset=noffset+4;
                   11520:        printf("# File is an UTF16BE BOM file\n");
                   11521:       }
                   11522:     } else{
                   11523:       ;/*printf(" Not a BOM file\n");*/
                   11524:     }
                   11525:   
1.197     brouard  11526:     /* If line starts with a # it is a comment */
1.277     brouard  11527:     if (line[noffset] == '#') {
1.197     brouard  11528:       numlinepar++;
                   11529:       fputs(line,stdout);
                   11530:       fputs(line,ficparo);
1.278     brouard  11531:       fputs(line,ficres);
1.197     brouard  11532:       fputs(line,ficlog);
                   11533:       continue;
                   11534:     }else
                   11535:       break;
                   11536:   }
                   11537:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11538:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11539:     if (num_filled != 5) {
                   11540:       printf("Should be 5 parameters\n");
1.283     brouard  11541:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11542:     }
1.126     brouard  11543:     numlinepar++;
1.197     brouard  11544:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11545:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11546:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11547:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11548:   }
                   11549:   /* Second parameter line */
                   11550:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11551:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11552:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11553:     if (line[0] == '#') {
                   11554:       numlinepar++;
1.283     brouard  11555:       printf("%s",line);
                   11556:       fprintf(ficres,"%s",line);
                   11557:       fprintf(ficparo,"%s",line);
                   11558:       fprintf(ficlog,"%s",line);
1.197     brouard  11559:       continue;
                   11560:     }else
                   11561:       break;
                   11562:   }
1.223     brouard  11563:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11564:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11565:     if (num_filled != 11) {
                   11566:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11567:       printf("but line=%s\n",line);
1.283     brouard  11568:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11569:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11570:     }
1.286     brouard  11571:     if( lastpass > maxwav){
                   11572:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11573:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11574:       fflush(ficlog);
                   11575:       goto end;
                   11576:     }
                   11577:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11578:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11579:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11580:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11581:   }
1.203     brouard  11582:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11583:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11584:   /* Third parameter line */
                   11585:   while(fgets(line, MAXLINE, ficpar)) {
                   11586:     /* If line starts with a # it is a comment */
                   11587:     if (line[0] == '#') {
                   11588:       numlinepar++;
1.283     brouard  11589:       printf("%s",line);
                   11590:       fprintf(ficres,"%s",line);
                   11591:       fprintf(ficparo,"%s",line);
                   11592:       fprintf(ficlog,"%s",line);
1.197     brouard  11593:       continue;
                   11594:     }else
                   11595:       break;
                   11596:   }
1.201     brouard  11597:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11598:     if (num_filled != 1){
1.302     brouard  11599:       printf("ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
                   11600:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
1.197     brouard  11601:       model[0]='\0';
                   11602:       goto end;
                   11603:     }
                   11604:     else{
                   11605:       if (model[0]=='+'){
                   11606:        for(i=1; i<=strlen(model);i++)
                   11607:          modeltemp[i-1]=model[i];
1.201     brouard  11608:        strcpy(model,modeltemp); 
1.197     brouard  11609:       }
                   11610:     }
1.199     brouard  11611:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11612:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11613:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11614:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11615:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11616:   }
                   11617:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11618:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11619:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11620:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11621:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11622:   fflush(ficlog);
1.190     brouard  11623:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11624:   if(model[0]=='#'){
1.279     brouard  11625:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11626:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11627:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11628:     if(mle != -1){
1.279     brouard  11629:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11630:       exit(1);
                   11631:     }
                   11632:   }
1.126     brouard  11633:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11634:     ungetc(c,ficpar);
                   11635:     fgets(line, MAXLINE, ficpar);
                   11636:     numlinepar++;
1.195     brouard  11637:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11638:       z[0]=line[1];
                   11639:     }
                   11640:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11641:     fputs(line, stdout);
                   11642:     //puts(line);
1.126     brouard  11643:     fputs(line,ficparo);
                   11644:     fputs(line,ficlog);
                   11645:   }
                   11646:   ungetc(c,ficpar);
                   11647: 
                   11648:    
1.290     brouard  11649:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11650:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11651:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11652:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11653:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11654:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11655:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11656:   */
                   11657:   if (strlen(model)>1) 
1.187     brouard  11658:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11659:   else
1.187     brouard  11660:     ncovmodel=2; /* Constant and age */
1.133     brouard  11661:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11662:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11663:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11664:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11665:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11666:     fflush(stdout);
                   11667:     fclose (ficlog);
                   11668:     goto end;
                   11669:   }
1.126     brouard  11670:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11671:   delti=delti3[1][1];
                   11672:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11673:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11674: /* We could also provide initial parameters values giving by simple logistic regression 
                   11675:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11676:       /* for(i=1;i<nlstate;i++){ */
                   11677:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11678:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11679:       /* } */
1.126     brouard  11680:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11681:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11682:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11683:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11684:     fclose (ficparo);
                   11685:     fclose (ficlog);
                   11686:     goto end;
                   11687:     exit(0);
1.220     brouard  11688:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11689:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11690:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11691:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11692:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11693:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11694:     hess=matrix(1,npar,1,npar);
1.220     brouard  11695:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11696:     /* Read guessed parameters */
1.126     brouard  11697:     /* Reads comments: lines beginning with '#' */
                   11698:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11699:       ungetc(c,ficpar);
                   11700:       fgets(line, MAXLINE, ficpar);
                   11701:       numlinepar++;
1.141     brouard  11702:       fputs(line,stdout);
1.126     brouard  11703:       fputs(line,ficparo);
                   11704:       fputs(line,ficlog);
                   11705:     }
                   11706:     ungetc(c,ficpar);
                   11707:     
                   11708:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11709:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11710:     for(i=1; i <=nlstate; i++){
1.234     brouard  11711:       j=0;
1.126     brouard  11712:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11713:        if(jj==i) continue;
                   11714:        j++;
1.292     brouard  11715:        while((c=getc(ficpar))=='#' && c!= EOF){
                   11716:          ungetc(c,ficpar);
                   11717:          fgets(line, MAXLINE, ficpar);
                   11718:          numlinepar++;
                   11719:          fputs(line,stdout);
                   11720:          fputs(line,ficparo);
                   11721:          fputs(line,ficlog);
                   11722:        }
                   11723:        ungetc(c,ficpar);
1.234     brouard  11724:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11725:        if ((i1 != i) || (j1 != jj)){
                   11726:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11727: It might be a problem of design; if ncovcol and the model are correct\n \
                   11728: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11729:          exit(1);
                   11730:        }
                   11731:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11732:        if(mle==1)
                   11733:          printf("%1d%1d",i,jj);
                   11734:        fprintf(ficlog,"%1d%1d",i,jj);
                   11735:        for(k=1; k<=ncovmodel;k++){
                   11736:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11737:          if(mle==1){
                   11738:            printf(" %lf",param[i][j][k]);
                   11739:            fprintf(ficlog," %lf",param[i][j][k]);
                   11740:          }
                   11741:          else
                   11742:            fprintf(ficlog," %lf",param[i][j][k]);
                   11743:          fprintf(ficparo," %lf",param[i][j][k]);
                   11744:        }
                   11745:        fscanf(ficpar,"\n");
                   11746:        numlinepar++;
                   11747:        if(mle==1)
                   11748:          printf("\n");
                   11749:        fprintf(ficlog,"\n");
                   11750:        fprintf(ficparo,"\n");
1.126     brouard  11751:       }
                   11752:     }  
                   11753:     fflush(ficlog);
1.234     brouard  11754:     
1.251     brouard  11755:     /* Reads parameters values */
1.126     brouard  11756:     p=param[1][1];
1.251     brouard  11757:     pstart=paramstart[1][1];
1.126     brouard  11758:     
                   11759:     /* Reads comments: lines beginning with '#' */
                   11760:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11761:       ungetc(c,ficpar);
                   11762:       fgets(line, MAXLINE, ficpar);
                   11763:       numlinepar++;
1.141     brouard  11764:       fputs(line,stdout);
1.126     brouard  11765:       fputs(line,ficparo);
                   11766:       fputs(line,ficlog);
                   11767:     }
                   11768:     ungetc(c,ficpar);
                   11769: 
                   11770:     for(i=1; i <=nlstate; i++){
                   11771:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11772:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11773:        if ( (i1-i) * (j1-j) != 0){
                   11774:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11775:          exit(1);
                   11776:        }
                   11777:        printf("%1d%1d",i,j);
                   11778:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11779:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11780:        for(k=1; k<=ncovmodel;k++){
                   11781:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11782:          printf(" %le",delti3[i][j][k]);
                   11783:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11784:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11785:        }
                   11786:        fscanf(ficpar,"\n");
                   11787:        numlinepar++;
                   11788:        printf("\n");
                   11789:        fprintf(ficparo,"\n");
                   11790:        fprintf(ficlog,"\n");
1.126     brouard  11791:       }
                   11792:     }
                   11793:     fflush(ficlog);
1.234     brouard  11794:     
1.145     brouard  11795:     /* Reads covariance matrix */
1.126     brouard  11796:     delti=delti3[1][1];
1.220     brouard  11797:                
                   11798:                
1.126     brouard  11799:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11800:                
1.126     brouard  11801:     /* Reads comments: lines beginning with '#' */
                   11802:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11803:       ungetc(c,ficpar);
                   11804:       fgets(line, MAXLINE, ficpar);
                   11805:       numlinepar++;
1.141     brouard  11806:       fputs(line,stdout);
1.126     brouard  11807:       fputs(line,ficparo);
                   11808:       fputs(line,ficlog);
                   11809:     }
                   11810:     ungetc(c,ficpar);
1.220     brouard  11811:                
1.126     brouard  11812:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11813:     hess=matrix(1,npar,1,npar);
1.131     brouard  11814:     for(i=1; i <=npar; i++)
                   11815:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11816:                
1.194     brouard  11817:     /* Scans npar lines */
1.126     brouard  11818:     for(i=1; i <=npar; i++){
1.226     brouard  11819:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11820:       if(count != 3){
1.226     brouard  11821:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11822: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11823: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11824:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11825: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11826: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11827:        exit(1);
1.220     brouard  11828:       }else{
1.226     brouard  11829:        if(mle==1)
                   11830:          printf("%1d%1d%d",i1,j1,jk);
                   11831:       }
                   11832:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11833:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11834:       for(j=1; j <=i; j++){
1.226     brouard  11835:        fscanf(ficpar," %le",&matcov[i][j]);
                   11836:        if(mle==1){
                   11837:          printf(" %.5le",matcov[i][j]);
                   11838:        }
                   11839:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11840:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11841:       }
                   11842:       fscanf(ficpar,"\n");
                   11843:       numlinepar++;
                   11844:       if(mle==1)
1.220     brouard  11845:                                printf("\n");
1.126     brouard  11846:       fprintf(ficlog,"\n");
                   11847:       fprintf(ficparo,"\n");
                   11848:     }
1.194     brouard  11849:     /* End of read covariance matrix npar lines */
1.126     brouard  11850:     for(i=1; i <=npar; i++)
                   11851:       for(j=i+1;j<=npar;j++)
1.226     brouard  11852:        matcov[i][j]=matcov[j][i];
1.126     brouard  11853:     
                   11854:     if(mle==1)
                   11855:       printf("\n");
                   11856:     fprintf(ficlog,"\n");
                   11857:     
                   11858:     fflush(ficlog);
                   11859:     
                   11860:   }    /* End of mle != -3 */
1.218     brouard  11861:   
1.186     brouard  11862:   /*  Main data
                   11863:    */
1.290     brouard  11864:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11865:   /* num=lvector(1,n); */
                   11866:   /* moisnais=vector(1,n); */
                   11867:   /* annais=vector(1,n); */
                   11868:   /* moisdc=vector(1,n); */
                   11869:   /* andc=vector(1,n); */
                   11870:   /* weight=vector(1,n); */
                   11871:   /* agedc=vector(1,n); */
                   11872:   /* cod=ivector(1,n); */
                   11873:   /* for(i=1;i<=n;i++){ */
                   11874:   num=lvector(firstobs,lastobs);
                   11875:   moisnais=vector(firstobs,lastobs);
                   11876:   annais=vector(firstobs,lastobs);
                   11877:   moisdc=vector(firstobs,lastobs);
                   11878:   andc=vector(firstobs,lastobs);
                   11879:   weight=vector(firstobs,lastobs);
                   11880:   agedc=vector(firstobs,lastobs);
                   11881:   cod=ivector(firstobs,lastobs);
                   11882:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11883:     num[i]=0;
                   11884:     moisnais[i]=0;
                   11885:     annais[i]=0;
                   11886:     moisdc[i]=0;
                   11887:     andc[i]=0;
                   11888:     agedc[i]=0;
                   11889:     cod[i]=0;
                   11890:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11891:   }
1.290     brouard  11892:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11893:   anint=matrix(1,maxwav,firstobs,lastobs);
1.325   ! brouard  11894:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */
        !          11895:   printf("BUG ncovmodel=%d NCOVMAX=%d 2**ncovmodel=%f BUG\n",ncovmodel,NCOVMAX,pow(2,ncovmodel));
1.126     brouard  11896:   tab=ivector(1,NCOVMAX);
1.144     brouard  11897:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11898:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11899: 
1.136     brouard  11900:   /* Reads data from file datafile */
                   11901:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11902:     goto end;
                   11903: 
                   11904:   /* Calculation of the number of parameters from char model */
1.234     brouard  11905:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11906:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11907:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11908:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11909:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11910:   */
                   11911:   
                   11912:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11913:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11914:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11915:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11916:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11917:   TvarF=ivector(1,NCOVMAX); /*  */
                   11918:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11919:   TvarV=ivector(1,NCOVMAX); /*  */
                   11920:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11921:   TvarA=ivector(1,NCOVMAX); /*  */
                   11922:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11923:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11924:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11925:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11926:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11927:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11928:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11929:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11930:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11931: 
1.230     brouard  11932:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11933:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11934:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11935:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11936:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11937:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11938:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11939:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11940:   */
                   11941:   /* For model-covariate k tells which data-covariate to use but
                   11942:     because this model-covariate is a construction we invent a new column
                   11943:     ncovcol + k1
                   11944:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11945:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11946:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11947:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11948:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11949:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11950:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11951:   */
1.145     brouard  11952:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11953:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11954:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11955:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11956:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11957:                         4 covariates (3 plus signs)
                   11958:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11959:                      */  
1.230     brouard  11960:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11961:                                * individual dummy, fixed or varying:
                   11962:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11963:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11964:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11965:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11966:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11967:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11968:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11969:                                * individual quantitative, fixed or varying:
                   11970:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11971:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11972:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11973: /* Main decodemodel */
                   11974: 
1.187     brouard  11975: 
1.223     brouard  11976:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11977:     goto end;
                   11978: 
1.137     brouard  11979:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11980:     nbwarn++;
                   11981:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11982:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11983:   }
1.136     brouard  11984:     /*  if(mle==1){*/
1.137     brouard  11985:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11986:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11987:   }
                   11988: 
                   11989:     /*-calculation of age at interview from date of interview and age at death -*/
                   11990:   agev=matrix(1,maxwav,1,imx);
                   11991: 
                   11992:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11993:     goto end;
                   11994: 
1.126     brouard  11995: 
1.136     brouard  11996:   agegomp=(int)agemin;
1.290     brouard  11997:   free_vector(moisnais,firstobs,lastobs);
                   11998:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11999:   /* free_matrix(mint,1,maxwav,1,n);
                   12000:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  12001:   /* free_vector(moisdc,1,n); */
                   12002:   /* free_vector(andc,1,n); */
1.145     brouard  12003:   /* */
                   12004:   
1.126     brouard  12005:   wav=ivector(1,imx);
1.214     brouard  12006:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   12007:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   12008:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   12009:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   12010:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   12011:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  12012:    
                   12013:   /* Concatenates waves */
1.214     brouard  12014:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   12015:      Death is a valid wave (if date is known).
                   12016:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   12017:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   12018:      and mw[mi+1][i]. dh depends on stepm.
                   12019:   */
                   12020: 
1.126     brouard  12021:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  12022:   /* Concatenates waves */
1.145     brouard  12023:  
1.290     brouard  12024:   free_vector(moisdc,firstobs,lastobs);
                   12025:   free_vector(andc,firstobs,lastobs);
1.215     brouard  12026: 
1.126     brouard  12027:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   12028:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   12029:   ncodemax[1]=1;
1.145     brouard  12030:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  12031:   cptcoveff=0;
1.220     brouard  12032:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   12033:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  12034:   }
                   12035:   
                   12036:   ncovcombmax=pow(2,cptcoveff);
                   12037:   invalidvarcomb=ivector(1, ncovcombmax); 
                   12038:   for(i=1;i<ncovcombmax;i++)
                   12039:     invalidvarcomb[i]=0;
                   12040:   
1.211     brouard  12041:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  12042:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  12043:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  12044:   
1.200     brouard  12045:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  12046:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  12047:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  12048:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   12049:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   12050:    * (currently 0 or 1) in the data.
                   12051:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   12052:    * corresponding modality (h,j).
                   12053:    */
                   12054: 
1.145     brouard  12055:   h=0;
                   12056:   /*if (cptcovn > 0) */
1.126     brouard  12057:   m=pow(2,cptcoveff);
                   12058:  
1.144     brouard  12059:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  12060:           * For k=4 covariates, h goes from 1 to m=2**k
                   12061:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   12062:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  12063:           *     h\k   1     2     3     4
1.143     brouard  12064:           *______________________________  
                   12065:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   12066:           *     2     2     1     1     1
                   12067:           *     3 i=2 1     2     1     1
                   12068:           *     4     2     2     1     1
                   12069:           *     5 i=3 1 i=2 1     2     1
                   12070:           *     6     2     1     2     1
                   12071:           *     7 i=4 1     2     2     1
                   12072:           *     8     2     2     2     1
1.197     brouard  12073:           *     9 i=5 1 i=3 1 i=2 1     2
                   12074:           *    10     2     1     1     2
                   12075:           *    11 i=6 1     2     1     2
                   12076:           *    12     2     2     1     2
                   12077:           *    13 i=7 1 i=4 1     2     2    
                   12078:           *    14     2     1     2     2
                   12079:           *    15 i=8 1     2     2     2
                   12080:           *    16     2     2     2     2
1.143     brouard  12081:           */
1.212     brouard  12082:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  12083:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   12084:      * and the value of each covariate?
                   12085:      * V1=1, V2=1, V3=2, V4=1 ?
                   12086:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   12087:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   12088:      * In order to get the real value in the data, we use nbcode
                   12089:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   12090:      * We are keeping this crazy system in order to be able (in the future?) 
                   12091:      * to have more than 2 values (0 or 1) for a covariate.
                   12092:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   12093:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   12094:      *              bbbbbbbb
                   12095:      *              76543210     
                   12096:      *   h-1        00000101 (6-1=5)
1.219     brouard  12097:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  12098:      *           &
                   12099:      *     1        00000001 (1)
1.219     brouard  12100:      *              00000000        = 1 & ((h-1) >> (k-1))
                   12101:      *          +1= 00000001 =1 
1.211     brouard  12102:      *
                   12103:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   12104:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   12105:      *    >>k'            11
                   12106:      *          &   00000001
                   12107:      *            = 00000001
                   12108:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   12109:      * Reverse h=6 and m=16?
                   12110:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   12111:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   12112:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   12113:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   12114:      * V3=decodtabm(14,3,2**4)=2
                   12115:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   12116:      *(h-1) >> (j-1)    0011 =13 >> 2
                   12117:      *          &1 000000001
                   12118:      *           = 000000001
                   12119:      *         +1= 000000010 =2
                   12120:      *                  2211
                   12121:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   12122:      *                  V3=2
1.220     brouard  12123:                 * codtabm and decodtabm are identical
1.211     brouard  12124:      */
                   12125: 
1.145     brouard  12126: 
                   12127:  free_ivector(Ndum,-1,NCOVMAX);
                   12128: 
                   12129: 
1.126     brouard  12130:     
1.186     brouard  12131:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  12132:   strcpy(optionfilegnuplot,optionfilefiname);
                   12133:   if(mle==-3)
1.201     brouard  12134:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  12135:   strcat(optionfilegnuplot,".gp");
                   12136: 
                   12137:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   12138:     printf("Problem with file %s",optionfilegnuplot);
                   12139:   }
                   12140:   else{
1.204     brouard  12141:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  12142:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  12143:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   12144:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  12145:   }
                   12146:   /*  fclose(ficgp);*/
1.186     brouard  12147: 
                   12148: 
                   12149:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  12150: 
                   12151:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   12152:   if(mle==-3)
1.201     brouard  12153:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  12154:   strcat(optionfilehtm,".htm");
                   12155:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  12156:     printf("Problem with %s \n",optionfilehtm);
                   12157:     exit(0);
1.126     brouard  12158:   }
                   12159: 
                   12160:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   12161:   strcat(optionfilehtmcov,"-cov.htm");
                   12162:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   12163:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   12164:   }
                   12165:   else{
                   12166:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   12167: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  12168: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  12169:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   12170:   }
                   12171: 
1.324     brouard  12172:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  12173: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   12174: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  12175: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  12176: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  12177: \n\
                   12178: <hr  size=\"2\" color=\"#EC5E5E\">\
                   12179:  <ul><li><h4>Parameter files</h4>\n\
                   12180:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   12181:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   12182:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   12183:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   12184:  - Date and time at start: %s</ul>\n",\
                   12185:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   12186:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   12187:          fileres,fileres,\
                   12188:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   12189:   fflush(fichtm);
                   12190: 
                   12191:   strcpy(pathr,path);
                   12192:   strcat(pathr,optionfilefiname);
1.184     brouard  12193: #ifdef WIN32
                   12194:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   12195: #else
1.126     brouard  12196:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  12197: #endif
                   12198:          
1.126     brouard  12199:   
1.220     brouard  12200:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   12201:                 and for any valid combination of covariates
1.126     brouard  12202:      and prints on file fileres'p'. */
1.251     brouard  12203:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  12204:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  12205: 
                   12206:   fprintf(fichtm,"\n");
1.286     brouard  12207:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  12208:          ftol, stepm);
                   12209:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   12210:   ncurrv=1;
                   12211:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   12212:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   12213:   ncurrv=i;
                   12214:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  12215:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  12216:   ncurrv=i;
                   12217:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  12218:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  12219:   ncurrv=i;
                   12220:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   12221:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   12222:           nlstate, ndeath, maxwav, mle, weightopt);
                   12223: 
                   12224:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   12225: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   12226: 
                   12227:   
1.317     brouard  12228:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Number of (used) observations=%d <br>\n\
1.126     brouard  12229: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   12230: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  12231:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  12232:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  12233:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   12234:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   12235:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   12236:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  12237: 
1.126     brouard  12238:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   12239:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   12240:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   12241: 
                   12242:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  12243:   /* For mortality only */
1.126     brouard  12244:   if (mle==-3){
1.136     brouard  12245:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  12246:     for(i=1;i<=NDIM;i++)
                   12247:       for(j=1;j<=NDIM;j++)
                   12248:        ximort[i][j]=0.;
1.186     brouard  12249:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  12250:     cens=ivector(firstobs,lastobs);
                   12251:     ageexmed=vector(firstobs,lastobs);
                   12252:     agecens=vector(firstobs,lastobs);
                   12253:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  12254:                
1.126     brouard  12255:     for (i=1; i<=imx; i++){
                   12256:       dcwave[i]=-1;
                   12257:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  12258:        if (s[m][i]>nlstate) {
                   12259:          dcwave[i]=m;
                   12260:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   12261:          break;
                   12262:        }
1.126     brouard  12263:     }
1.226     brouard  12264:     
1.126     brouard  12265:     for (i=1; i<=imx; i++) {
                   12266:       if (wav[i]>0){
1.226     brouard  12267:        ageexmed[i]=agev[mw[1][i]][i];
                   12268:        j=wav[i];
                   12269:        agecens[i]=1.; 
                   12270:        
                   12271:        if (ageexmed[i]> 1 && wav[i] > 0){
                   12272:          agecens[i]=agev[mw[j][i]][i];
                   12273:          cens[i]= 1;
                   12274:        }else if (ageexmed[i]< 1) 
                   12275:          cens[i]= -1;
                   12276:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   12277:          cens[i]=0 ;
1.126     brouard  12278:       }
                   12279:       else cens[i]=-1;
                   12280:     }
                   12281:     
                   12282:     for (i=1;i<=NDIM;i++) {
                   12283:       for (j=1;j<=NDIM;j++)
1.226     brouard  12284:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  12285:     }
                   12286:     
1.302     brouard  12287:     p[1]=0.0268; p[NDIM]=0.083;
                   12288:     /* printf("%lf %lf", p[1], p[2]); */
1.126     brouard  12289:     
                   12290:     
1.136     brouard  12291: #ifdef GSL
                   12292:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  12293: #else
1.126     brouard  12294:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  12295: #endif
1.201     brouard  12296:     strcpy(filerespow,"POW-MORT_"); 
                   12297:     strcat(filerespow,fileresu);
1.126     brouard  12298:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   12299:       printf("Problem with resultfile: %s\n", filerespow);
                   12300:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   12301:     }
1.136     brouard  12302: #ifdef GSL
                   12303:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  12304: #else
1.126     brouard  12305:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  12306: #endif
1.126     brouard  12307:     /*  for (i=1;i<=nlstate;i++)
                   12308:        for(j=1;j<=nlstate+ndeath;j++)
                   12309:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   12310:     */
                   12311:     fprintf(ficrespow,"\n");
1.136     brouard  12312: #ifdef GSL
                   12313:     /* gsl starts here */ 
                   12314:     T = gsl_multimin_fminimizer_nmsimplex;
                   12315:     gsl_multimin_fminimizer *sfm = NULL;
                   12316:     gsl_vector *ss, *x;
                   12317:     gsl_multimin_function minex_func;
                   12318: 
                   12319:     /* Initial vertex size vector */
                   12320:     ss = gsl_vector_alloc (NDIM);
                   12321:     
                   12322:     if (ss == NULL){
                   12323:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   12324:     }
                   12325:     /* Set all step sizes to 1 */
                   12326:     gsl_vector_set_all (ss, 0.001);
                   12327: 
                   12328:     /* Starting point */
1.126     brouard  12329:     
1.136     brouard  12330:     x = gsl_vector_alloc (NDIM);
                   12331:     
                   12332:     if (x == NULL){
                   12333:       gsl_vector_free(ss);
                   12334:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   12335:     }
                   12336:   
                   12337:     /* Initialize method and iterate */
                   12338:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  12339:     /*     gsl_vector_set(x, 0, 0.0268); */
                   12340:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  12341:     gsl_vector_set(x, 0, p[1]);
                   12342:     gsl_vector_set(x, 1, p[2]);
                   12343: 
                   12344:     minex_func.f = &gompertz_f;
                   12345:     minex_func.n = NDIM;
                   12346:     minex_func.params = (void *)&p; /* ??? */
                   12347:     
                   12348:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   12349:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   12350:     
                   12351:     printf("Iterations beginning .....\n\n");
                   12352:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   12353: 
                   12354:     iteri=0;
                   12355:     while (rval == GSL_CONTINUE){
                   12356:       iteri++;
                   12357:       status = gsl_multimin_fminimizer_iterate(sfm);
                   12358:       
                   12359:       if (status) printf("error: %s\n", gsl_strerror (status));
                   12360:       fflush(0);
                   12361:       
                   12362:       if (status) 
                   12363:         break;
                   12364:       
                   12365:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   12366:       ssval = gsl_multimin_fminimizer_size (sfm);
                   12367:       
                   12368:       if (rval == GSL_SUCCESS)
                   12369:         printf ("converged to a local maximum at\n");
                   12370:       
                   12371:       printf("%5d ", iteri);
                   12372:       for (it = 0; it < NDIM; it++){
                   12373:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   12374:       }
                   12375:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   12376:     }
                   12377:     
                   12378:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   12379:     
                   12380:     gsl_vector_free(x); /* initial values */
                   12381:     gsl_vector_free(ss); /* inital step size */
                   12382:     for (it=0; it<NDIM; it++){
                   12383:       p[it+1]=gsl_vector_get(sfm->x,it);
                   12384:       fprintf(ficrespow," %.12lf", p[it]);
                   12385:     }
                   12386:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   12387: #endif
                   12388: #ifdef POWELL
                   12389:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   12390: #endif  
1.126     brouard  12391:     fclose(ficrespow);
                   12392:     
1.203     brouard  12393:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  12394: 
                   12395:     for(i=1; i <=NDIM; i++)
                   12396:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  12397:                                matcov[i][j]=matcov[j][i];
1.126     brouard  12398:     
                   12399:     printf("\nCovariance matrix\n ");
1.203     brouard  12400:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  12401:     for(i=1; i <=NDIM; i++) {
                   12402:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  12403:                                printf("%f ",matcov[i][j]);
                   12404:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  12405:       }
1.203     brouard  12406:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  12407:     }
                   12408:     
                   12409:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  12410:     for (i=1;i<=NDIM;i++) {
1.126     brouard  12411:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  12412:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   12413:     }
1.302     brouard  12414:     lsurv=vector(agegomp,AGESUP);
                   12415:     lpop=vector(agegomp,AGESUP);
                   12416:     tpop=vector(agegomp,AGESUP);
1.126     brouard  12417:     lsurv[agegomp]=100000;
                   12418:     
                   12419:     for (k=agegomp;k<=AGESUP;k++) {
                   12420:       agemortsup=k;
                   12421:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   12422:     }
                   12423:     
                   12424:     for (k=agegomp;k<agemortsup;k++)
                   12425:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   12426:     
                   12427:     for (k=agegomp;k<agemortsup;k++){
                   12428:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   12429:       sumlpop=sumlpop+lpop[k];
                   12430:     }
                   12431:     
                   12432:     tpop[agegomp]=sumlpop;
                   12433:     for (k=agegomp;k<(agemortsup-3);k++){
                   12434:       /*  tpop[k+1]=2;*/
                   12435:       tpop[k+1]=tpop[k]-lpop[k];
                   12436:     }
                   12437:     
                   12438:     
                   12439:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   12440:     for (k=agegomp;k<(agemortsup-2);k++) 
                   12441:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   12442:     
                   12443:     
                   12444:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  12445:                ageminpar=50;
                   12446:                agemaxpar=100;
1.194     brouard  12447:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   12448:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12449: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12450: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   12451:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12452: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12453: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12454:     }else{
                   12455:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   12456:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  12457:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  12458:                }
1.201     brouard  12459:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  12460:                     stepm, weightopt,\
                   12461:                     model,imx,p,matcov,agemortsup);
                   12462:     
1.302     brouard  12463:     free_vector(lsurv,agegomp,AGESUP);
                   12464:     free_vector(lpop,agegomp,AGESUP);
                   12465:     free_vector(tpop,agegomp,AGESUP);
1.220     brouard  12466:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  12467:     free_ivector(dcwave,firstobs,lastobs);
                   12468:     free_vector(agecens,firstobs,lastobs);
                   12469:     free_vector(ageexmed,firstobs,lastobs);
                   12470:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  12471: #ifdef GSL
1.136     brouard  12472: #endif
1.186     brouard  12473:   } /* Endof if mle==-3 mortality only */
1.205     brouard  12474:   /* Standard  */
                   12475:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   12476:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12477:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  12478:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  12479:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12480:     for (k=1; k<=npar;k++)
                   12481:       printf(" %d %8.5f",k,p[k]);
                   12482:     printf("\n");
1.205     brouard  12483:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   12484:       /* mlikeli uses func not funcone */
1.247     brouard  12485:       /* for(i=1;i<nlstate;i++){ */
                   12486:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   12487:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   12488:       /* } */
1.205     brouard  12489:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   12490:     }
                   12491:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   12492:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12493:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   12494:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12495:     }
                   12496:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  12497:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12498:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12499:     for (k=1; k<=npar;k++)
                   12500:       printf(" %d %8.5f",k,p[k]);
                   12501:     printf("\n");
                   12502:     
                   12503:     /*--------- results files --------------*/
1.283     brouard  12504:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  12505:     
                   12506:     
                   12507:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
1.319     brouard  12508:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n"); /* Printing model equation */
1.126     brouard  12509:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
1.319     brouard  12510: 
                   12511:     printf("#model=  1      +     age ");
                   12512:     fprintf(ficres,"#model=  1      +     age ");
                   12513:     fprintf(ficlog,"#model=  1      +     age ");
                   12514:     fprintf(fichtm,"\n<ul><li> model=1+age+%s\n \
                   12515: </ul>", model);
                   12516: 
                   12517:     fprintf(fichtm,"\n<table style=\"text-align:center; border: 1px solid\">\n");
                   12518:     fprintf(fichtm, "<tr><th>Model=</th><th>1</th><th>+ age</th>");
                   12519:     if(nagesqr==1){
                   12520:       printf("  + age*age  ");
                   12521:       fprintf(ficres,"  + age*age  ");
                   12522:       fprintf(ficlog,"  + age*age  ");
                   12523:       fprintf(fichtm, "<th>+ age*age</th>");
                   12524:     }
                   12525:     for(j=1;j <=ncovmodel-2;j++){
                   12526:       if(Typevar[j]==0) {
                   12527:        printf("  +      V%d  ",Tvar[j]);
                   12528:        fprintf(ficres,"  +      V%d  ",Tvar[j]);
                   12529:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   12530:        fprintf(fichtm, "<th>+ V%d</th>",Tvar[j]);
                   12531:       }else if(Typevar[j]==1) {
                   12532:        printf("  +    V%d*age ",Tvar[j]);
                   12533:        fprintf(ficres,"  +    V%d*age ",Tvar[j]);
                   12534:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   12535:        fprintf(fichtm, "<th>+  V%d*age</th>",Tvar[j]);
                   12536:       }else if(Typevar[j]==2) {
                   12537:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12538:        fprintf(ficres,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12539:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12540:        fprintf(fichtm, "<th>+  V%d*V%d</th>",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12541:       }
                   12542:     }
                   12543:     printf("\n");
                   12544:     fprintf(ficres,"\n");
                   12545:     fprintf(ficlog,"\n");
                   12546:     fprintf(fichtm, "</tr>");
                   12547:     fprintf(fichtm, "\n");
                   12548:     
                   12549:     
1.126     brouard  12550:     for(i=1,jk=1; i <=nlstate; i++){
                   12551:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  12552:        if (k != i) {
1.319     brouard  12553:          fprintf(fichtm, "<tr>");
1.225     brouard  12554:          printf("%d%d ",i,k);
                   12555:          fprintf(ficlog,"%d%d ",i,k);
                   12556:          fprintf(ficres,"%1d%1d ",i,k);
1.319     brouard  12557:          fprintf(fichtm, "<td>%1d%1d</td>",i,k);
1.225     brouard  12558:          for(j=1; j <=ncovmodel; j++){
                   12559:            printf("%12.7f ",p[jk]);
                   12560:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12561:            fprintf(ficres,"%12.7f ",p[jk]);
1.319     brouard  12562:            fprintf(fichtm, "<td>%12.7f</td>",p[jk]);
1.225     brouard  12563:            jk++; 
                   12564:          }
                   12565:          printf("\n");
                   12566:          fprintf(ficlog,"\n");
                   12567:          fprintf(ficres,"\n");
1.319     brouard  12568:          fprintf(fichtm, "</tr>\n");
1.225     brouard  12569:        }
1.126     brouard  12570:       }
                   12571:     }
1.319     brouard  12572:     /* fprintf(fichtm,"</tr>\n"); */
                   12573:     fprintf(fichtm,"</table>\n");
                   12574:     fprintf(fichtm, "\n");
                   12575: 
1.203     brouard  12576:     if(mle != 0){
                   12577:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12578:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12579:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12580:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12581:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
1.322     brouard  12582:       fprintf(fichtm, "\n<p>The Wald test results are output only if the maximimzation of the Likelihood is performed (mle=1)\n</br>Parameters, Wald tests and Wald-based confidence intervals\n</br> W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n</br> And Wald-based confidence intervals plus and minus 1.96 * W \n </br> It might be better to visualize the covariance matrix. See the page '<a href=\"%s\">Matrix of variance-covariance of one-step probabilities and its graphs</a>'.\n</br>",optionfilehtmcov);
1.319     brouard  12583:       fprintf(fichtm,"\n<table style=\"text-align:center; border: 1px solid\">");
                   12584:       fprintf(fichtm, "\n<tr><th>Model=</th><th>1</th><th>+ age</th>");
                   12585:       if(nagesqr==1){
                   12586:        printf("  + age*age  ");
                   12587:        fprintf(ficres,"  + age*age  ");
                   12588:        fprintf(ficlog,"  + age*age  ");
                   12589:        fprintf(fichtm, "<th>+ age*age</th>");
                   12590:       }
                   12591:       for(j=1;j <=ncovmodel-2;j++){
                   12592:        if(Typevar[j]==0) {
                   12593:          printf("  +      V%d  ",Tvar[j]);
                   12594:          fprintf(fichtm, "<th>+ V%d</th>",Tvar[j]);
                   12595:        }else if(Typevar[j]==1) {
                   12596:          printf("  +    V%d*age ",Tvar[j]);
                   12597:          fprintf(fichtm, "<th>+  V%d*age</th>",Tvar[j]);
                   12598:        }else if(Typevar[j]==2) {
                   12599:          fprintf(fichtm, "<th>+  V%d*V%d</th>",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   12600:        }
                   12601:       }
                   12602:       fprintf(fichtm, "</tr>\n");
                   12603:  
1.203     brouard  12604:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12605:        for(k=1; k <=(nlstate+ndeath); k++){
                   12606:          if (k != i) {
1.319     brouard  12607:            fprintf(fichtm, "<tr valign=top>");
1.225     brouard  12608:            printf("%d%d ",i,k);
                   12609:            fprintf(ficlog,"%d%d ",i,k);
1.319     brouard  12610:            fprintf(fichtm, "<td>%1d%1d</td>",i,k);
1.225     brouard  12611:            for(j=1; j <=ncovmodel; j++){
1.319     brouard  12612:              wald=p[jk]/sqrt(matcov[jk][jk]);
1.324     brouard  12613:              printf("%12.7f(%12.7f) W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk],sqrt(matcov[jk][jk]), p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12614:              fprintf(ficlog,"%12.7f(%12.7f) W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk],sqrt(matcov[jk][jk]), p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
1.319     brouard  12615:              if(fabs(wald) > 1.96){
1.321     brouard  12616:                fprintf(fichtm, "<td><b>%12.7f</b></br> (%12.7f)</br>",p[jk],sqrt(matcov[jk][jk]));
1.319     brouard  12617:              }else{
                   12618:                fprintf(fichtm, "<td>%12.7f (%12.7f)</br>",p[jk],sqrt(matcov[jk][jk]));
                   12619:              }
1.324     brouard  12620:              fprintf(fichtm,"W=%8.3f</br>",wald);
1.319     brouard  12621:              fprintf(fichtm,"[%12.7f;%12.7f]</br></td>", p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
1.225     brouard  12622:              jk++; 
                   12623:            }
                   12624:            printf("\n");
                   12625:            fprintf(ficlog,"\n");
1.319     brouard  12626:            fprintf(fichtm, "</tr>\n");
1.225     brouard  12627:          }
                   12628:        }
1.193     brouard  12629:       }
1.203     brouard  12630:     } /* end of hesscov and Wald tests */
1.319     brouard  12631:     fprintf(fichtm,"</table>\n");
1.225     brouard  12632:     
1.203     brouard  12633:     /*  */
1.126     brouard  12634:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12635:     printf("# Scales (for hessian or gradient estimation)\n");
                   12636:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12637:     for(i=1,jk=1; i <=nlstate; i++){
                   12638:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12639:        if (j!=i) {
                   12640:          fprintf(ficres,"%1d%1d",i,j);
                   12641:          printf("%1d%1d",i,j);
                   12642:          fprintf(ficlog,"%1d%1d",i,j);
                   12643:          for(k=1; k<=ncovmodel;k++){
                   12644:            printf(" %.5e",delti[jk]);
                   12645:            fprintf(ficlog," %.5e",delti[jk]);
                   12646:            fprintf(ficres," %.5e",delti[jk]);
                   12647:            jk++;
                   12648:          }
                   12649:          printf("\n");
                   12650:          fprintf(ficlog,"\n");
                   12651:          fprintf(ficres,"\n");
                   12652:        }
1.126     brouard  12653:       }
                   12654:     }
                   12655:     
                   12656:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12657:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12658:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12659:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12660:     /* # 121 Var(a12)\n\ */
                   12661:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12662:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12663:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12664:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12665:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12666:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12667:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12668:     
                   12669:     
                   12670:     /* Just to have a covariance matrix which will be more understandable
                   12671:        even is we still don't want to manage dictionary of variables
                   12672:     */
                   12673:     for(itimes=1;itimes<=2;itimes++){
                   12674:       jj=0;
                   12675:       for(i=1; i <=nlstate; i++){
1.225     brouard  12676:        for(j=1; j <=nlstate+ndeath; j++){
                   12677:          if(j==i) continue;
                   12678:          for(k=1; k<=ncovmodel;k++){
                   12679:            jj++;
                   12680:            ca[0]= k+'a'-1;ca[1]='\0';
                   12681:            if(itimes==1){
                   12682:              if(mle>=1)
                   12683:                printf("#%1d%1d%d",i,j,k);
                   12684:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12685:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12686:            }else{
                   12687:              if(mle>=1)
                   12688:                printf("%1d%1d%d",i,j,k);
                   12689:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12690:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12691:            }
                   12692:            ll=0;
                   12693:            for(li=1;li <=nlstate; li++){
                   12694:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12695:                if(lj==li) continue;
                   12696:                for(lk=1;lk<=ncovmodel;lk++){
                   12697:                  ll++;
                   12698:                  if(ll<=jj){
                   12699:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12700:                    if(ll<jj){
                   12701:                      if(itimes==1){
                   12702:                        if(mle>=1)
                   12703:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12704:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12705:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12706:                      }else{
                   12707:                        if(mle>=1)
                   12708:                          printf(" %.5e",matcov[jj][ll]); 
                   12709:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12710:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12711:                      }
                   12712:                    }else{
                   12713:                      if(itimes==1){
                   12714:                        if(mle>=1)
                   12715:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12716:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12717:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12718:                      }else{
                   12719:                        if(mle>=1)
                   12720:                          printf(" %.7e",matcov[jj][ll]); 
                   12721:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12722:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12723:                      }
                   12724:                    }
                   12725:                  }
                   12726:                } /* end lk */
                   12727:              } /* end lj */
                   12728:            } /* end li */
                   12729:            if(mle>=1)
                   12730:              printf("\n");
                   12731:            fprintf(ficlog,"\n");
                   12732:            fprintf(ficres,"\n");
                   12733:            numlinepar++;
                   12734:          } /* end k*/
                   12735:        } /*end j */
1.126     brouard  12736:       } /* end i */
                   12737:     } /* end itimes */
                   12738:     
                   12739:     fflush(ficlog);
                   12740:     fflush(ficres);
1.225     brouard  12741:     while(fgets(line, MAXLINE, ficpar)) {
                   12742:       /* If line starts with a # it is a comment */
                   12743:       if (line[0] == '#') {
                   12744:        numlinepar++;
                   12745:        fputs(line,stdout);
                   12746:        fputs(line,ficparo);
                   12747:        fputs(line,ficlog);
1.299     brouard  12748:        fputs(line,ficres);
1.225     brouard  12749:        continue;
                   12750:       }else
                   12751:        break;
                   12752:     }
                   12753:     
1.209     brouard  12754:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12755:     /*   ungetc(c,ficpar); */
                   12756:     /*   fgets(line, MAXLINE, ficpar); */
                   12757:     /*   fputs(line,stdout); */
                   12758:     /*   fputs(line,ficparo); */
                   12759:     /* } */
                   12760:     /* ungetc(c,ficpar); */
1.126     brouard  12761:     
                   12762:     estepm=0;
1.209     brouard  12763:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12764:       
                   12765:       if (num_filled != 6) {
                   12766:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12767:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12768:        goto end;
                   12769:       }
                   12770:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12771:     }
                   12772:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12773:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12774:     
1.209     brouard  12775:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12776:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12777:     if (fage <= 2) {
                   12778:       bage = ageminpar;
                   12779:       fage = agemaxpar;
                   12780:     }
                   12781:     
                   12782:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12783:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12784:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12785:                
1.186     brouard  12786:     /* Other stuffs, more or less useful */    
1.254     brouard  12787:     while(fgets(line, MAXLINE, ficpar)) {
                   12788:       /* If line starts with a # it is a comment */
                   12789:       if (line[0] == '#') {
                   12790:        numlinepar++;
                   12791:        fputs(line,stdout);
                   12792:        fputs(line,ficparo);
                   12793:        fputs(line,ficlog);
1.299     brouard  12794:        fputs(line,ficres);
1.254     brouard  12795:        continue;
                   12796:       }else
                   12797:        break;
                   12798:     }
                   12799: 
                   12800:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12801:       
                   12802:       if (num_filled != 7) {
                   12803:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12804:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12805:        goto end;
                   12806:       }
                   12807:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12808:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12809:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12810:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12811:     }
1.254     brouard  12812: 
                   12813:     while(fgets(line, MAXLINE, ficpar)) {
                   12814:       /* If line starts with a # it is a comment */
                   12815:       if (line[0] == '#') {
                   12816:        numlinepar++;
                   12817:        fputs(line,stdout);
                   12818:        fputs(line,ficparo);
                   12819:        fputs(line,ficlog);
1.299     brouard  12820:        fputs(line,ficres);
1.254     brouard  12821:        continue;
                   12822:       }else
                   12823:        break;
1.126     brouard  12824:     }
                   12825:     
                   12826:     
                   12827:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12828:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12829:     
1.254     brouard  12830:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12831:       if (num_filled != 1) {
                   12832:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12833:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12834:        goto end;
                   12835:       }
                   12836:       printf("pop_based=%d\n",popbased);
                   12837:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12838:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12839:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12840:     }
                   12841:      
1.258     brouard  12842:     /* Results */
1.307     brouard  12843:     endishere=0;
1.258     brouard  12844:     nresult=0;
1.308     brouard  12845:     parameterline=0;
1.258     brouard  12846:     do{
                   12847:       if(!fgets(line, MAXLINE, ficpar)){
                   12848:        endishere=1;
1.308     brouard  12849:        parameterline=15;
1.258     brouard  12850:       }else if (line[0] == '#') {
                   12851:        /* If line starts with a # it is a comment */
1.254     brouard  12852:        numlinepar++;
                   12853:        fputs(line,stdout);
                   12854:        fputs(line,ficparo);
                   12855:        fputs(line,ficlog);
1.299     brouard  12856:        fputs(line,ficres);
1.254     brouard  12857:        continue;
1.258     brouard  12858:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12859:        parameterline=11;
1.296     brouard  12860:       else if(sscanf(line,"prevbackcast=%[^\n]\n",modeltemp))
1.258     brouard  12861:        parameterline=12;
1.307     brouard  12862:       else if(sscanf(line,"result:%[^\n]\n",modeltemp)){
1.258     brouard  12863:        parameterline=13;
1.307     brouard  12864:       }
1.258     brouard  12865:       else{
                   12866:        parameterline=14;
1.254     brouard  12867:       }
1.308     brouard  12868:       switch (parameterline){ /* =0 only if only comments */
1.258     brouard  12869:       case 11:
1.296     brouard  12870:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12871:                  fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.258     brouard  12872:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12873:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12874:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12875:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12876:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12877:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
1.296     brouard  12878:           prvforecast = 1;
                   12879:        } 
                   12880:        else if((num_filled=sscanf(line,"prevforecast=%d yearsfproj=%lf mobil_average=%d\n",&prevfcast,&yrfproj,&mobilavproj)) !=EOF){/* && (num_filled == 3))*/
1.313     brouard  12881:          printf("prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12882:          fprintf(ficlog,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12883:          fprintf(ficres,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
1.296     brouard  12884:           prvforecast = 2;
                   12885:        }
                   12886:        else {
                   12887:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearsfproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12888:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12889:          goto end;
1.258     brouard  12890:        }
1.254     brouard  12891:        break;
1.258     brouard  12892:       case 12:
1.296     brouard  12893:        if((num_filled=sscanf(line,"prevbackcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&prevbcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12894:           fprintf(ficparo,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12895:          printf("prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12896:          fprintf(ficlog,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12897:          fprintf(ficres,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12898:          /* day and month of back2 are not used but only year anback2.*/
1.273     brouard  12899:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12900:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.296     brouard  12901:           prvbackcast = 1;
                   12902:        } 
                   12903:        else if((num_filled=sscanf(line,"prevbackcast=%d yearsbproj=%lf mobil_average=%d\n",&prevbcast,&yrbproj,&mobilavproj)) ==3){/* && (num_filled == 3))*/
1.313     brouard  12904:          printf("prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12905:          fprintf(ficlog,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12906:          fprintf(ficres,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
1.296     brouard  12907:           prvbackcast = 2;
                   12908:        }
                   12909:        else {
                   12910:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearsbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12911:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12912:          goto end;
1.258     brouard  12913:        }
1.230     brouard  12914:        break;
1.258     brouard  12915:       case 13:
1.307     brouard  12916:        num_filled=sscanf(line,"result:%[^\n]\n",resultline);
                   12917:        nresult++; /* Sum of resultlines */
                   12918:        printf("Result %d: result:%s\n",nresult, resultline);
1.318     brouard  12919:        if(nresult > MAXRESULTLINESPONE-1){
                   12920:          printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINESPONE-1,nresult,rfileres);
                   12921:          fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINESPONE-1,nresult,rfileres);
1.307     brouard  12922:          goto end;
                   12923:        }
1.310     brouard  12924:        if(!decoderesult(resultline, nresult)){ /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.314     brouard  12925:          fprintf(ficparo,"result: %s\n",resultline);
                   12926:          fprintf(ficres,"result: %s\n",resultline);
                   12927:          fprintf(ficlog,"result: %s\n",resultline);
1.310     brouard  12928:        } else
                   12929:          goto end;
1.307     brouard  12930:        break;
                   12931:       case 14:
                   12932:        printf("Error: Unknown command '%s'\n",line);
                   12933:        fprintf(ficlog,"Error: Unknown command '%s'\n",line);
1.314     brouard  12934:        if(line[0] == ' ' || line[0] == '\n'){
                   12935:          printf("It should not be an empty line '%s'\n",line);
                   12936:          fprintf(ficlog,"It should not be an empty line '%s'\n",line);
                   12937:        }         
1.307     brouard  12938:        if(ncovmodel >=2 && nresult==0 ){
                   12939:          printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
                   12940:          fprintf(ficlog,"ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12941:        }
1.307     brouard  12942:        /* goto end; */
                   12943:        break;
1.308     brouard  12944:       case 15:
                   12945:        printf("End of resultlines.\n");
                   12946:        fprintf(ficlog,"End of resultlines.\n");
                   12947:        break;
                   12948:       default: /* parameterline =0 */
1.307     brouard  12949:        nresult=1;
                   12950:        decoderesult(".",nresult ); /* No covariate */
1.258     brouard  12951:       } /* End switch parameterline */
                   12952:     }while(endishere==0); /* End do */
1.126     brouard  12953:     
1.230     brouard  12954:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12955:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12956:     
                   12957:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12958:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12959:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12960: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12961: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12962:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12963: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12964: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12965:     }else{
1.270     brouard  12966:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
1.296     brouard  12967:       /* It seems that anprojd which is computed from the mean year at interview which is known yet because of freqsummary */
                   12968:       /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */ /* Done in freqsummary */
                   12969:       if(prvforecast==1){
                   12970:         dateprojd=(jproj1+12*mproj1+365*anproj1)/365;
                   12971:         jprojd=jproj1;
                   12972:         mprojd=mproj1;
                   12973:         anprojd=anproj1;
                   12974:         dateprojf=(jproj2+12*mproj2+365*anproj2)/365;
                   12975:         jprojf=jproj2;
                   12976:         mprojf=mproj2;
                   12977:         anprojf=anproj2;
                   12978:       } else if(prvforecast == 2){
                   12979:         dateprojd=dateintmean;
                   12980:         date2dmy(dateprojd,&jprojd, &mprojd, &anprojd);
                   12981:         dateprojf=dateintmean+yrfproj;
                   12982:         date2dmy(dateprojf,&jprojf, &mprojf, &anprojf);
                   12983:       }
                   12984:       if(prvbackcast==1){
                   12985:         datebackd=(jback1+12*mback1+365*anback1)/365;
                   12986:         jbackd=jback1;
                   12987:         mbackd=mback1;
                   12988:         anbackd=anback1;
                   12989:         datebackf=(jback2+12*mback2+365*anback2)/365;
                   12990:         jbackf=jback2;
                   12991:         mbackf=mback2;
                   12992:         anbackf=anback2;
                   12993:       } else if(prvbackcast == 2){
                   12994:         datebackd=dateintmean;
                   12995:         date2dmy(datebackd,&jbackd, &mbackd, &anbackd);
                   12996:         datebackf=dateintmean-yrbproj;
                   12997:         date2dmy(datebackf,&jbackf, &mbackf, &anbackf);
                   12998:       }
                   12999:       
                   13000:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, prevbcast, pathc,p, (int)anprojd-bage, (int)anbackd-fage);
1.220     brouard  13001:     }
                   13002:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.296     brouard  13003:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,prevbcast, estepm, \
                   13004:                 jprev1,mprev1,anprev1,dateprev1, dateprojd, datebackd,jprev2,mprev2,anprev2,dateprev2,dateprojf, datebackf);
1.220     brouard  13005:                
1.225     brouard  13006:     /*------------ free_vector  -------------*/
                   13007:     /*  chdir(path); */
1.220     brouard  13008:                
1.215     brouard  13009:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   13010:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   13011:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   13012:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  13013:     free_lvector(num,firstobs,lastobs);
                   13014:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  13015:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   13016:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   13017:     fclose(ficparo);
                   13018:     fclose(ficres);
1.220     brouard  13019:                
                   13020:                
1.186     brouard  13021:     /* Other results (useful)*/
1.220     brouard  13022:                
                   13023:                
1.126     brouard  13024:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  13025:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   13026:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  13027:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  13028:     fclose(ficrespl);
                   13029: 
                   13030:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  13031:     /*#include "hpijx.h"*/
                   13032:     hPijx(p, bage, fage);
1.145     brouard  13033:     fclose(ficrespij);
1.227     brouard  13034:     
1.220     brouard  13035:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  13036:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  13037:     k=1;
1.126     brouard  13038:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  13039:     
1.269     brouard  13040:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   13041:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   13042:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  13043:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  13044:        for(k=1;k<=ncovcombmax;k++)
                   13045:          probs[i][j][k]=0.;
1.269     brouard  13046:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   13047:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  13048:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  13049:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   13050:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  13051:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  13052:          for(k=1;k<=ncovcombmax;k++)
                   13053:            mobaverages[i][j][k]=0.;
1.219     brouard  13054:       mobaverage=mobaverages;
                   13055:       if (mobilav!=0) {
1.235     brouard  13056:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  13057:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  13058:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   13059:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   13060:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   13061:        }
1.269     brouard  13062:       } else if (mobilavproj !=0) {
1.235     brouard  13063:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  13064:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  13065:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   13066:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   13067:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   13068:        }
1.269     brouard  13069:       }else{
                   13070:        printf("Internal error moving average\n");
                   13071:        fflush(stdout);
                   13072:        exit(1);
1.219     brouard  13073:       }
                   13074:     }/* end if moving average */
1.227     brouard  13075:     
1.126     brouard  13076:     /*---------- Forecasting ------------------*/
1.296     brouard  13077:     if(prevfcast==1){ 
                   13078:       /*   /\*    if(stepm ==1){*\/ */
                   13079:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   13080:       /*This done previously after freqsummary.*/
                   13081:       /*   dateprojd=(jproj1+12*mproj1+365*anproj1)/365; */
                   13082:       /*   dateprojf=(jproj2+12*mproj2+365*anproj2)/365; */
                   13083:       
                   13084:       /* } else if (prvforecast==2){ */
                   13085:       /*   /\*    if(stepm ==1){*\/ */
                   13086:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   13087:       /* } */
                   13088:       /*prevforecast(fileresu, dateintmean, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);*/
                   13089:       prevforecast(fileresu,dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, p, cptcoveff);
1.126     brouard  13090:     }
1.269     brouard  13091: 
1.296     brouard  13092:     /* Prevbcasting */
                   13093:     if(prevbcast==1){
1.219     brouard  13094:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   13095:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   13096:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   13097: 
                   13098:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   13099: 
                   13100:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  13101: 
1.219     brouard  13102:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   13103:       fclose(ficresplb);
                   13104: 
1.222     brouard  13105:       hBijx(p, bage, fage, mobaverage);
                   13106:       fclose(ficrespijb);
1.219     brouard  13107: 
1.296     brouard  13108:       /* /\* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, *\/ */
                   13109:       /* /\*                  mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); *\/ */
                   13110:       /* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, */
                   13111:       /*                      mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
                   13112:       prevbackforecast(fileresu, mobaverage, dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2,
                   13113:                       mobilavproj, bage, fage, firstpass, lastpass, p, cptcoveff);
                   13114: 
                   13115:       
1.269     brouard  13116:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  13117: 
                   13118:       
1.269     brouard  13119:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  13120:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   13121:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   13122:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.296     brouard  13123:     }    /* end  Prevbcasting */
1.268     brouard  13124:  
1.186     brouard  13125:  
                   13126:     /* ------ Other prevalence ratios------------ */
1.126     brouard  13127: 
1.215     brouard  13128:     free_ivector(wav,1,imx);
                   13129:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   13130:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   13131:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  13132:                
                   13133:                
1.127     brouard  13134:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  13135:                
1.201     brouard  13136:     strcpy(filerese,"E_");
                   13137:     strcat(filerese,fileresu);
1.126     brouard  13138:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   13139:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   13140:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   13141:     }
1.208     brouard  13142:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   13143:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  13144: 
                   13145:     pstamp(ficreseij);
1.219     brouard  13146:                
1.235     brouard  13147:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   13148:     if (cptcovn < 1){i1=1;}
                   13149:     
                   13150:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   13151:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  13152:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  13153:        continue;
1.219     brouard  13154:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  13155:       printf("\n#****** ");
1.225     brouard  13156:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  13157:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  13158:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13159:       }
                   13160:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13161:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13162:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  13163:       }
                   13164:       fprintf(ficreseij,"******\n");
1.235     brouard  13165:       printf("******\n");
1.219     brouard  13166:       
                   13167:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   13168:       oldm=oldms;savm=savms;
1.235     brouard  13169:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  13170:       
1.219     brouard  13171:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  13172:     }
                   13173:     fclose(ficreseij);
1.208     brouard  13174:     printf("done evsij\n");fflush(stdout);
                   13175:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  13176: 
1.218     brouard  13177:                
1.227     brouard  13178:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  13179:                
1.201     brouard  13180:     strcpy(filerest,"T_");
                   13181:     strcat(filerest,fileresu);
1.127     brouard  13182:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   13183:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   13184:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   13185:     }
1.208     brouard  13186:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   13187:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  13188:     strcpy(fileresstde,"STDE_");
                   13189:     strcat(fileresstde,fileresu);
1.126     brouard  13190:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  13191:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   13192:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  13193:     }
1.227     brouard  13194:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   13195:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  13196: 
1.201     brouard  13197:     strcpy(filerescve,"CVE_");
                   13198:     strcat(filerescve,fileresu);
1.126     brouard  13199:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  13200:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   13201:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  13202:     }
1.227     brouard  13203:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   13204:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  13205: 
1.201     brouard  13206:     strcpy(fileresv,"V_");
                   13207:     strcat(fileresv,fileresu);
1.126     brouard  13208:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   13209:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   13210:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   13211:     }
1.227     brouard  13212:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   13213:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  13214: 
1.235     brouard  13215:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   13216:     if (cptcovn < 1){i1=1;}
                   13217:     
                   13218:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   13219:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  13220:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  13221:        continue;
1.321     brouard  13222:       printf("\n# model %s \n#****** Result for:", model);
                   13223:       fprintf(ficrest,"\n# model %s \n#****** Result for:", model);
                   13224:       fprintf(ficlog,"\n# model %s \n#****** Result for:", model);
1.227     brouard  13225:       for(j=1;j<=cptcoveff;j++){ 
                   13226:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13227:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13228:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13229:       }
1.235     brouard  13230:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13231:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13232:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13233:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13234:       }        
1.208     brouard  13235:       fprintf(ficrest,"******\n");
1.227     brouard  13236:       fprintf(ficlog,"******\n");
                   13237:       printf("******\n");
1.208     brouard  13238:       
                   13239:       fprintf(ficresstdeij,"\n#****** ");
                   13240:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  13241:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  13242:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   13243:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  13244:       }
1.235     brouard  13245:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13246:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13247:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13248:       }        
1.208     brouard  13249:       fprintf(ficresstdeij,"******\n");
                   13250:       fprintf(ficrescveij,"******\n");
                   13251:       
                   13252:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  13253:       /* pstamp(ficresvij); */
1.225     brouard  13254:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  13255:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  13256:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   13257:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   13258:       }        
1.208     brouard  13259:       fprintf(ficresvij,"******\n");
                   13260:       
                   13261:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   13262:       oldm=oldms;savm=savms;
1.235     brouard  13263:       printf(" cvevsij ");
                   13264:       fprintf(ficlog, " cvevsij ");
                   13265:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  13266:       printf(" end cvevsij \n ");
                   13267:       fprintf(ficlog, " end cvevsij \n ");
                   13268:       
                   13269:       /*
                   13270:        */
                   13271:       /* goto endfree; */
                   13272:       
                   13273:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   13274:       pstamp(ficrest);
                   13275:       
1.269     brouard  13276:       epj=vector(1,nlstate+1);
1.208     brouard  13277:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  13278:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   13279:        cptcod= 0; /* To be deleted */
                   13280:        printf("varevsij vpopbased=%d \n",vpopbased);
                   13281:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  13282:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  13283:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   13284:        if(vpopbased==1)
                   13285:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   13286:        else
1.288     brouard  13287:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  13288:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   13289:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   13290:        fprintf(ficrest,"\n");
                   13291:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  13292:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   13293:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  13294:        for(age=bage; age <=fage ;age++){
1.235     brouard  13295:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  13296:          if (vpopbased==1) {
                   13297:            if(mobilav ==0){
                   13298:              for(i=1; i<=nlstate;i++)
                   13299:                prlim[i][i]=probs[(int)age][i][k];
                   13300:            }else{ /* mobilav */ 
                   13301:              for(i=1; i<=nlstate;i++)
                   13302:                prlim[i][i]=mobaverage[(int)age][i][k];
                   13303:            }
                   13304:          }
1.219     brouard  13305:          
1.227     brouard  13306:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   13307:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   13308:          /* printf(" age %4.0f ",age); */
                   13309:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   13310:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   13311:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   13312:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   13313:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   13314:            }
                   13315:            epj[nlstate+1] +=epj[j];
                   13316:          }
                   13317:          /* printf(" age %4.0f \n",age); */
1.219     brouard  13318:          
1.227     brouard  13319:          for(i=1, vepp=0.;i <=nlstate;i++)
                   13320:            for(j=1;j <=nlstate;j++)
                   13321:              vepp += vareij[i][j][(int)age];
                   13322:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   13323:          for(j=1;j <=nlstate;j++){
                   13324:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   13325:          }
                   13326:          fprintf(ficrest,"\n");
                   13327:        }
1.208     brouard  13328:       } /* End vpopbased */
1.269     brouard  13329:       free_vector(epj,1,nlstate+1);
1.208     brouard  13330:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   13331:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  13332:       printf("done selection\n");fflush(stdout);
                   13333:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  13334:       
1.235     brouard  13335:     } /* End k selection */
1.227     brouard  13336: 
                   13337:     printf("done State-specific expectancies\n");fflush(stdout);
                   13338:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   13339: 
1.288     brouard  13340:     /* variance-covariance of forward period prevalence*/
1.269     brouard  13341:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  13342: 
1.227     brouard  13343:     
1.290     brouard  13344:     free_vector(weight,firstobs,lastobs);
1.227     brouard  13345:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  13346:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   13347:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   13348:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   13349:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  13350:     free_ivector(tab,1,NCOVMAX);
                   13351:     fclose(ficresstdeij);
                   13352:     fclose(ficrescveij);
                   13353:     fclose(ficresvij);
                   13354:     fclose(ficrest);
                   13355:     fclose(ficpar);
                   13356:     
                   13357:     
1.126     brouard  13358:     /*---------- End : free ----------------*/
1.219     brouard  13359:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  13360:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   13361:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  13362:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   13363:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  13364:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  13365:   /* endfree:*/
                   13366:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   13367:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   13368:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  13369:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   13370:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   13371:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   13372:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  13373:   free_matrix(matcov,1,npar,1,npar);
                   13374:   free_matrix(hess,1,npar,1,npar);
                   13375:   /*free_vector(delti,1,npar);*/
                   13376:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   13377:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  13378:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  13379:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   13380:   
                   13381:   free_ivector(ncodemax,1,NCOVMAX);
                   13382:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   13383:   free_ivector(Dummy,-1,NCOVMAX);
                   13384:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  13385:   free_ivector(DummyV,1,NCOVMAX);
                   13386:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  13387:   free_ivector(Typevar,-1,NCOVMAX);
                   13388:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  13389:   free_ivector(TvarsQ,1,NCOVMAX);
                   13390:   free_ivector(TvarsQind,1,NCOVMAX);
                   13391:   free_ivector(TvarsD,1,NCOVMAX);
                   13392:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  13393:   free_ivector(TvarFD,1,NCOVMAX);
                   13394:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  13395:   free_ivector(TvarF,1,NCOVMAX);
                   13396:   free_ivector(TvarFind,1,NCOVMAX);
                   13397:   free_ivector(TvarV,1,NCOVMAX);
                   13398:   free_ivector(TvarVind,1,NCOVMAX);
                   13399:   free_ivector(TvarA,1,NCOVMAX);
                   13400:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  13401:   free_ivector(TvarFQ,1,NCOVMAX);
                   13402:   free_ivector(TvarFQind,1,NCOVMAX);
                   13403:   free_ivector(TvarVD,1,NCOVMAX);
                   13404:   free_ivector(TvarVDind,1,NCOVMAX);
                   13405:   free_ivector(TvarVQ,1,NCOVMAX);
                   13406:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  13407:   free_ivector(Tvarsel,1,NCOVMAX);
                   13408:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  13409:   free_ivector(Tposprod,1,NCOVMAX);
                   13410:   free_ivector(Tprod,1,NCOVMAX);
                   13411:   free_ivector(Tvaraff,1,NCOVMAX);
                   13412:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   13413:   free_ivector(Tage,1,NCOVMAX);
                   13414:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  13415:   free_ivector(TmodelInvind,1,NCOVMAX);
                   13416:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  13417:   
                   13418:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   13419:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  13420:   fflush(fichtm);
                   13421:   fflush(ficgp);
                   13422:   
1.227     brouard  13423:   
1.126     brouard  13424:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  13425:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   13426:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  13427:   }else{
                   13428:     printf("End of Imach\n");
                   13429:     fprintf(ficlog,"End of Imach\n");
                   13430:   }
                   13431:   printf("See log file on %s\n",filelog);
                   13432:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  13433:   /*(void) gettimeofday(&end_time,&tzp);*/
                   13434:   rend_time = time(NULL);  
                   13435:   end_time = *localtime(&rend_time);
                   13436:   /* tml = *localtime(&end_time.tm_sec); */
                   13437:   strcpy(strtend,asctime(&end_time));
1.126     brouard  13438:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   13439:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  13440:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  13441:   
1.157     brouard  13442:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   13443:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   13444:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  13445:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   13446: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   13447:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13448:   fclose(fichtm);
                   13449:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13450:   fclose(fichtmcov);
                   13451:   fclose(ficgp);
                   13452:   fclose(ficlog);
                   13453:   /*------ End -----------*/
1.227     brouard  13454:   
1.281     brouard  13455: 
                   13456: /* Executes gnuplot */
1.227     brouard  13457:   
                   13458:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  13459: #ifdef WIN32
1.227     brouard  13460:   if (_chdir(pathcd) != 0)
                   13461:     printf("Can't move to directory %s!\n",path);
                   13462:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  13463: #else
1.227     brouard  13464:     if(chdir(pathcd) != 0)
                   13465:       printf("Can't move to directory %s!\n", path);
                   13466:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  13467: #endif 
1.126     brouard  13468:     printf("Current directory %s!\n",pathcd);
                   13469:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   13470:   sprintf(plotcmd,"gnuplot");
1.157     brouard  13471: #ifdef _WIN32
1.126     brouard  13472:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   13473: #endif
                   13474:   if(!stat(plotcmd,&info)){
1.158     brouard  13475:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13476:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  13477:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  13478:     }else
                   13479:       strcpy(pplotcmd,plotcmd);
1.157     brouard  13480: #ifdef __unix
1.126     brouard  13481:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   13482:     if(!stat(plotcmd,&info)){
1.158     brouard  13483:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13484:     }else
                   13485:       strcpy(pplotcmd,plotcmd);
                   13486: #endif
                   13487:   }else
                   13488:     strcpy(pplotcmd,plotcmd);
                   13489:   
                   13490:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  13491:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.292     brouard  13492:   strcpy(pplotcmd,plotcmd);
1.227     brouard  13493:   
1.126     brouard  13494:   if((outcmd=system(plotcmd)) != 0){
1.292     brouard  13495:     printf("Error in gnuplot, command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  13496:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  13497:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.292     brouard  13498:     if((outcmd=system(plotcmd)) != 0){
1.153     brouard  13499:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.292     brouard  13500:       strcpy(plotcmd,pplotcmd);
                   13501:     }
1.126     brouard  13502:   }
1.158     brouard  13503:   printf(" Successful, please wait...");
1.126     brouard  13504:   while (z[0] != 'q') {
                   13505:     /* chdir(path); */
1.154     brouard  13506:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  13507:     scanf("%s",z);
                   13508: /*     if (z[0] == 'c') system("./imach"); */
                   13509:     if (z[0] == 'e') {
1.158     brouard  13510: #ifdef __APPLE__
1.152     brouard  13511:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  13512: #elif __linux
                   13513:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  13514: #else
1.152     brouard  13515:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  13516: #endif
                   13517:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   13518:       system(pplotcmd);
1.126     brouard  13519:     }
                   13520:     else if (z[0] == 'g') system(plotcmd);
                   13521:     else if (z[0] == 'q') exit(0);
                   13522:   }
1.227     brouard  13523: end:
1.126     brouard  13524:   while (z[0] != 'q') {
1.195     brouard  13525:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  13526:     scanf("%s",z);
                   13527:   }
1.283     brouard  13528:   printf("End\n");
1.282     brouard  13529:   exit(0);
1.126     brouard  13530: }

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