DESS IDP Paris I (N. Brouard)
14 juin 1995, 3 hours, without document
The original exam did consist in two exercises and a problem. Only the problem has been translated until now.
Questions are in italics and proposed solution in roman. This exam can be found on the WEB/Internet : http://sauvy.ined.fr/ brouard/enseignement
Problem: Force of mortality at very old ages
We are interested in analyzing mortality at very old ages and
particularly on the shape of the mortality force beyond age 90.
Let us take the example of a woman who is supposed to be
120. We will take into account the possibility of identity swap
between mother and daughter.
The daughter is supposed to be exactly 20 years younger than her
mother and to have died at age 40.
To simplify we use a recent period life table which is
far from the 1874 cohort life table but similar at high ages.
Mortality rate (or force) at age 40, , is about 2.28 per thousand per year and is about 75.39 per thousand per year at age 80. Give the expression of the force of the Gompertz law at age x:
and
from which:
Assuming that 6 billion humans are alive at age 90,
how many will reach age 120 using the Gompertz
assumption?
What can you infer from these results about the possibility for a
country like France (population: 58 million) to have a senior citizen
aged 120?
If six billion people are aged 90, only =0,0198 individual(s) could survive until age 120! The standard deviation of this binomial law , = 0,27 is also very small proving that there cannot be any human survivor.
In the case where force of mortality is constant, the survival function, sc, is a decreasing exponential:
Answer the previous questions with the hypothesis of a constant force instead of a Gompertz law.
From the 6 billion people, millions would now have reached age 120!
Result is straight forward:
Probability is easily derived:
The probability of living 60 more years differs if you are 40 or 60 years old. How significant is this difference in the case of the Gompertz assumption? Is this a proof of mistaken identity?
The probability for the 40 year old daughter to reach age 100 is 7 per thousand whereas there is no chance for the 60 year old mother to have reach age 120.
If the Gompertz law still holds after age 90, the mistaken hypothesis is validated: there was an identity swap.
Figure 1: Hypotheses concerning mortality forces beyond age 90: constant or Gompertz.
The computation of the new probabilities follows:
and
Figure 2: Conditional probability of surviving for a human aged
90 according to two hypotheses: constant mortality force or
extension of a Gompertz line.
Figures 1 and 2 summarize the hypotheses on the mortality force and on its consequences on the survival curves.
In the case of a constant mortality force beyond age 90, the probability for the mother to survive until age 120 is only 7 times lower than the probability of the daughter to reach age 100.
Research at high ages and in particular on centenarians is necessary to have better estimates on mortality at age hundred and above. Nevertheless, if the force of mortality at very old age was plateauing among humans, like it seems to be verified for insects like drosophila we should find many 120 year olds in China!